Page last updated: 2024-08-18

thiophenes and rp 40749

thiophenes has been researched along with rp 40749 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199013 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berstad, S; Hanssen, LE; Larsen, S; Linnestad, P; Lorentzen-Lund, S; Mosvold, J; Myren, J; Osnes, M; Stave, R; Valnes, K1
Chayvialle, JA; Couture, E; Forichon, J; Minaire, Y1
Barthélémy, C; Forichon, J; Minaire, Y; Simon, J; Woehrlé, R1
Bonfils, S; Denis, P; Frydman, A; Galmiche, JP; Garcia del Risco, F; Mignon, M; Piat, M; Teule, M1
Barthélemy, C; Simon, J; Woehrlé, R1
Ranløv, PJ; Rosetzsky, A; Stubgaard, M1
Cunningham, MG; De Peyer, R; Frydman, AM; Garoflid-Oprescu, NA; Griessen, M; Loizeau, E; Malè, PJ1
Lamers, CB; Nelis, GF; Pals, G1
Forichon, J; Minaire, Y; Woehrle, R1
Nelis, GF1
Bosc, F; Pagniez, R; Toulet, J; Vienne, JL; Viteau, JM1
Blancafort, E; Bonfils, S; Garcia del Risco, F; Mignon, M; Renard, A; Sauvage, M; Simon, J1
Derégnaucort, J; Hardy-Houis, M1

Trials

6 trial(s) available for thiophenes and rp 40749

ArticleYear
The antisecretory effects of RP 40 749 in patients with previous duodenal ulcer.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:8

    Topics: Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Gastric Acid; Gastrins; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Pancreatic Polypeptide; Pepsin A; Placebos; Somatostatin; Thiophenes; Time Factors

1985
Inhibition of histalog-stimulated gastric secretion by 40 749 RP, a new long-acting gastric antisecretory agent.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:10

    Topics: Adult; Betazole; Gastric Acid; Gastric Juice; Humans; Kinetics; Male; Placebos; Pyrazoles; Thiophenes; Time Factors

1985
A new H+ suppressor: RP 40 749 versus placebo and cimetidine. Ambulatory 48-hour intragastric pH monitoring in normal men.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:8

    Topics: Adult; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Gastric Acid; Humans; Hydrogen-Ion Concentration; Male; Monitoring, Physiologic; Placebos; Random Allocation; Tablets; Thiophenes

1985
Inhibition of pentagastrin-stimulated gastric secretion by pyridyl-2-tetrahydrothiophene derivative (RP 40749)
    Lancet (London, England), 1982, May-22, Volume: 1, Issue:8282

    Topics: Adult; Double-Blind Method; Gastric Juice; Humans; Male; Pentagastrin; Secretory Rate; Thiophenes

1982
RP 40749 in treatment of duodenal ulcer.
    Lancet (London, England), 1984, Apr-07, Volume: 1, Issue:8380

    Topics: Acute Disease; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Thiophenes

1984
[Efficacy of a new antisecretory agent (40 749 RP) on human gastric secretion induced by a meal (intragastric titration)].
    Gastroenterologie clinique et biologique, 1984, Volume: 8, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Eating; Female; Gastric Acid; Gastric Emptying; Humans; Male; Thiophenes; Time Factors

1984

Other Studies

7 other study(ies) available for thiophenes and rp 40749

ArticleYear
Effect of 40749 RP on basal and sham feeding stimulated gastric secretion in man.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:5

    Topics: Adult; Anti-Ulcer Agents; Double-Blind Method; Gastric Acid; Gastric Mucosa; Gastrointestinal Hormones; Humans; Male; Pepsin A; Random Allocation; Thiophenes

1987
Increased effect of multiple doses of 40 749 RP a new long acting gastric antisecretory agent.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Depression, Chemical; Double-Blind Method; Female; Gastric Acid; Humans; Male; Pentagastrin; Random Allocation; Thiophenes; Time Factors

1986
Acute and chronic 24-hour gastric pH and pharmacokinetic studies with a long acting antisecretory drug (40749 RP) in peptic ulcer.
    Gastroenterologie clinique et biologique, 1986, Volume: 10, Issue:5

    Topics: Adult; Aged; Anti-Ulcer Agents; Drug Evaluation; Duodenal Ulcer; Female; Gastric Acid; Gastrins; Humans; Kinetics; Male; Middle Aged; Thiophenes; Time Factors

1986
Effects of single daily doses of a pyridil-2-tetrahydrothiophene derivative (40749 RP) on 24 hour H+ activity, nocturnal acid output, gastrin and pepsinogen I profiles in duodenal ulcer patients.
    Gut, 1986, Volume: 27, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Cimetidine; Depression, Chemical; Drug Evaluation; Duodenal Ulcer; Gastric Acid; Gastric Juice; Gastrins; Humans; Hydrogen-Ion Concentration; Male; Pepsinogens; Thiophenes; Time Factors

1986
Influence of RP 40749 on basal and meal-stimulated serum-gastrin, serum-pepsinogen I, and gastrin-content of the antral mucosa in duodenal ulcer patients.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:7

    Topics: Adult; Aged; Anti-Ulcer Agents; Creatinine; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenoscopy; Female; Gastric Mucosa; Gastrins; Humans; Male; Middle Aged; Pepsinogens; Pyloric Antrum; Thiophenes

1985
[Inhibition by a 2-pyridyltetrahydrothiophene derivative (40749 RP) of gastric secretion stimulated by pentagastrin. Results in 30 duodenal ulcer patients].
    Gastroenterologie clinique et biologique, 1984, Volume: 8, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Duodenal Ulcer; Female; Gastric Juice; Humans; Male; Pentagastrin; Thiophenes

1984
[Antisecretory and antiulcer activities of N-methyl-2-(2-pyridyl)-2,3,4,5,-tetrahydro-2-thiophene-carbothioamide (R.P. .40, 749) (author's transl)].
    Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982, Mar-22, Volume: 294, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Juice; Rats; Stomach Ulcer; Thiophenes

1982