Page last updated: 2024-08-18

thiophenes and rep8839

thiophenes has been researched along with rep8839 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Critchley, IA; Ochsner, UA1
Ayers, DF; Bullard, JM; Dean, F; Green, LS; Janjic, N; Jarvis, TC; Ochsner, UA; Ribble, W1
Bell, SJ; Colagiovanni, DB; Faqi, AS; Gill, S1
Hussain, T; Sharma, A; Yogavel, M1
Jirgensons, A; O'Neill, AJ; Randall, CP; Rasina, D1

Reviews

1 review(s) available for thiophenes and rep8839

ArticleYear
Recent advances in the preclinical evaluation of the topical antibacterial agent REP8839.
    Current opinion in chemical biology, 2008, Volume: 12, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Diamines; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Humans; Methionine-tRNA Ligase; Thiophenes

2008

Other Studies

4 other study(ies) available for thiophenes and rep8839

ArticleYear
Inhibition of methionyl-tRNA synthetase by REP8839 and effects of resistance mutations on enzyme activity.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Diamines; Humans; Methionine; Methionine-tRNA Ligase; Molecular Structure; Mutation; Staphylococcus aureus; Structure-Activity Relationship; Thiophenes

2009
An intranasal irritation assessment of antibacterial ointment alone or in combination with mupirocin versus Bactroban Nasal in rabbits.
    Regulatory toxicology and pharmacology : RTP, 2009, Volume: 55, Issue:1

    Topics: Administration, Intranasal; Animals; Anti-Bacterial Agents; Biological Availability; Diamines; Dose-Response Relationship, Drug; Drug Combinations; Edema; Erythema; Female; Irritants; Male; Mupirocin; Nasal Mucosa; Nose; Ointments; Rabbits; Thiophenes

2009
Inhibition of protein synthesis and malaria parasite development by drug targeting of methionyl-tRNA synthetases.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:4

    Topics: Animals; Antimalarials; Benzopyrans; Computer Simulation; Cytoplasm; Diamines; Drug Discovery; Drug Evaluation, Preclinical; Erythrocytes; Humans; Methionine-tRNA Ligase; Models, Molecular; Plasmodium falciparum; Protein Synthesis Inhibitors; Thiophenes

2015
Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10

    Topics: Amino Acyl-tRNA Synthetases; Anti-Bacterial Agents; Boron Compounds; Diamines; Drug Resistance, Bacterial; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Targeted Therapy; Mupirocin; Mutation Rate; Staphylococcus aureus; Thiophenes

2016