thiophenes has been researched along with purmorphamine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bee, WL; Copeland, RA; Davenport, EA; Gilmartin, A; Gontarek, R; Hornberger, KR; Kallal, LA; Lai, Z; Lawrie, K; Lu, Q; McMillan, L; Rominger, CM; Rominger, DH; Truong, M; Tummino, PJ; Turunen, B; Will, M; Zuercher, WJ | 1 |
| Ames, RS; Bee, WT; Davenport, EA; Hornberger, KR; Kallal, LA; Li, H; McMillan, L; Truong, M; Turunen, B; Will, M; Xie, W; Zuercher, WJ | 1 |
| Krieg, PA; Lewis, C | 1 |
| Baumann, M; Brause, A; Eickhoff, J; Flegel, J; Hennes, E; Inoue, T; Janning, P; Kordes, S; Kremer, L; Matsubayashi, HT; Mejdrová, I; Nencka, R; Nihongaki, Y; Robke, L; Schöler, HR; Sterneckert, J; Ursu, A; Waldmann, H; Ziegler, S | 1 |
| Bowin, CF; Cañizal, MCA; Hoffmann, C; Inoue, A; Kozielewicz, P; Ono, Y; Petersen, J; Schulte, G; Turku, A; Valnohova, J | 1 |
1 review(s) available for thiophenes and purmorphamine
| Article | Year |
|---|---|
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cilia; Gene Expression; Hedgehog Proteins; Humans; Mice; Minor Histocompatibility Antigens; Morpholines; Osteogenesis; Phosphotransferases (Alcohol Group Acceptor); Purines; RNA Interference; RNA, Small Interfering; Signal Transduction; Smoothened Receptor; Structure-Activity Relationship; Thiophenes | 2019 |
4 other study(ies) available for thiophenes and purmorphamine
| Article | Year |
|---|---|
Evidence for allosteric interactions of antagonist binding to the smoothened receptor.
Topics: Anilides; Animals; Benzamides; Benzimidazoles; beta-Lactamases; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Cyclohexylamines; Genes, Reporter; Humans; Kinetics; Mice; Molecular Structure; Morpholines; NIH 3T3 Cells; Piperazines; Purines; Pyrazoles; Pyridines; Radioligand Assay; Receptors, G-Protein-Coupled; Recombinant Proteins; Smoothened Receptor; Thiophenes; Tomatine; Transfection; Veratrum Alkaloids | 2009 |
The development of a high-content screening binding assay for the smoothened receptor.
Topics: Algorithms; Baculoviridae; Benzamides; Benzimidazoles; Cell Line; Cyclohexylamines; Drug Evaluation, Preclinical; Fluorescent Dyes; Genes, Reporter; HEK293 Cells; High-Throughput Screening Assays; Humans; Morpholines; Piperazines; Protein Binding; Purines; Pyrazoles; Receptors, G-Protein-Coupled; Smoothened Receptor; Thiophenes | 2012 |
Reagents for developmental regulation of Hedgehog signaling.
Topics: Animals; Cyclohexylamines; Embryo Culture Techniques; Embryonic Development; Gene Expression Regulation, Developmental; Hedgehog Proteins; Morpholines; Purines; Signal Transduction; Thiophenes; Veratrum Alkaloids; Xenopus | 2014 |
Structural insight into small molecule action on Frizzleds.
Topics: Cell Membrane; Dishevelled Proteins; Drug Discovery; Frizzled Receptors; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Targeted Therapy; Morpholines; Proof of Concept Study; Protein Interaction Domains and Motifs; Purines; Pyridines; Smoothened Receptor; Structure-Activity Relationship; Thiophenes; Wnt Signaling Pathway | 2020 |