thiophenes has been researched along with prostaglandin d2 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barr, RM; Black, AK; Dowd, PM; Greaves, MW; Isaacs, JL; Koro, O; Mistry, K | 1 |
| Abbate, R; Breschi, C; Costanzo, G; Favilla, S; Gensini, GF; Neri Serneri, GG | 1 |
| Bonta, IL; de Wit, CM; Vincent, JE; Zijlstra, FJ | 1 |
| Arimura, A; Asanuma, F; Hashizume, H; Hiramatsu, Y; Honma, T; Inagaki, M; Kida, S; Kishino, J; Mitsumori, S; Ohtani, M; Okada, T; Tsuri, T; Yasui, K | 1 |
| Arimura, A; Deguchi, M; Hattori, M; Hirano, Y; Nagira, M; Nishitani, Y; Shichijo, M; Suzuki, N | 1 |
| Arimura, A; Asanuma, F; Deguchi, M; Hirano, Y; Shichijo, M; Yasui, K | 1 |
| Arnold, B; Kolaczkowska, E; Opdenakker, G; Piccard, H; Plytycz, B | 1 |
| Abraham, WM; Arimura, A; Deguchi, M; Hirano, Y; Shichijo, M; Suzuki, N; Yasui, K | 1 |
| Kaur, S; Liebel, FT; Southall, MD; Sur, R | 1 |
| Aoyagi, H; Choi, YH; Lee, SN; Park, B; Shin, DM; Yamasaki, Y; Yoo, JY; Yoon, HG; Yoon, JH | 1 |
| Christman, JW; van Breemen, RB; Xiao, L; Yu, R; Zhao, G | 1 |
| Cao, H; Christman, JW; Deng, J; Li, Y; Ornatowska, M; Sadikot, RT; Xiao, L; Yu, R; Zhao, G; Zhao, Q | 1 |
| Chen, C; Du, J; Li, HH; Meng, Y; Tian, C | 1 |
1 trial(s) available for thiophenes and prostaglandin d2
| Article | Year |
|---|---|
Ticlopidine activity on platelet function in patients with enhanced platelet aggregation. A short-term crossover study.
Topics: Adenosine Diphosphate; Adult; Aged; beta-Thromboglobulin; Bleeding Time; Blood Platelets; Collagen; Epoprostenol; Humans; Male; Middle Aged; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Thiophenes; Thromboxane B2; Ticlopidine | 1983 |
12 other study(ies) available for thiophenes and prostaglandin d2
| Article | Year |
|---|---|
The in vitro 5-lipoxygenase and cyclo-oxygenase inhibitor L-652,343 does not inhibit 5-lipoxygenase in vivo in human skin.
Topics: Adult; Arachidonate Lipoxygenases; Cyclooxygenase Inhibitors; Dinoprostone; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Psoriasis; Skin; Thiophenes | 1988 |
The effect of 5-(2-chlorobenzyl)-5,6,7,7a-tetrahydro 4H-thieno (3.2-C)-pyridine-2-one hydrochloride (PCR 3787), a metabolite of ticlopidine, on the aggregation of human platelets in vitro and on the aggregation inhibiting action of PGI2 and PGD2.
Topics: Collagen; Epoprostenol; Humans; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Thiophenes; Ticlopidine | 1984 |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives.
Topics: Administration, Oral; Airway Obstruction; Animals; Anti-Allergic Agents; Asthma; Blood Platelets; Bridged Bicyclo Compounds; Capillary Permeability; Conjunctiva; Cyclic AMP; Eosinophils; Guinea Pigs; Heptanes; Humans; Prostaglandin D2; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial; Stereoisomerism; Structure-Activity Relationship; Thiophenes | 2003 |
Synergistic effect of PGD2 via prostanoid DP receptor on TNF-alpha-induced production of MCP-1 and IL-8 in human monocytic THP-1 cells.
Topics: Cell Line, Tumor; Chemokine CCL2; Chemokines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Heptanoic Acids; Humans; Interleukin-8; Monocytes; Prostaglandin D2; Protein Kinases; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction; Thiophenes; Tumor Necrosis Factor-alpha | 2007 |
Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Intranasal; Allergens; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Male; Nasal Mucosa; Nasal Obstruction; Nose; Ovalbumin; Pressure; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial; Thiophenes; Time Factors | 2008 |
Increased cyclooxygenase activity impairs apoptosis of inflammatory neutrophils in mice lacking gelatinase B/matrix metalloproteinase-9.
Topics: Animals; Apoptosis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Male; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Knockout; Neutrophil Infiltration; Neutrophils; Peritonitis; Prostaglandin D2; Pyrazoles; Thiophenes; Zymosan | 2009 |
A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cyclic AMP; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Prostaglandin D2; Quinolines; Receptors, Immunologic; Receptors, Prostaglandin; Sulfides; Thiophenes; Time Factors | 2009 |
Induction of prostaglandin D2 through the p38 MAPK pathway is responsible for the antipruritic activity of sertaconazole nitrate.
Topics: Administration, Topical; Animals; Antifungal Agents; Cell Degranulation; Cell Line; Drug Interactions; Histamine; Imidazoles; Indoles; Macrophages; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Pruritus; Rats; Receptors, Prostaglandin; Thiophenes | 2010 |
The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling.
Topics: Cell Line; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Intramolecular Oxidoreductases; Lipocalins; MAP Kinase Signaling System; Mucin-5B; Phosphorylation; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Respiratory Mucosa; Response Elements; Ribosomal Protein S6 Kinases, 90-kDa; Thiophenes | 2011 |
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2.
Topics: 4-Butyrolactone; Animals; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dibenzocycloheptenes; Dinoprostone; Enzyme Assays; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Isomerases; Lipocalins; Macrophages; Mice; Mice, Inbred C57BL; Piperidines; Prostaglandin D2; Prostaglandin H2; Prostaglandin-E Synthases; Sheep; Thiophenes | 2011 |
Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages.
Topics: 4-Butyrolactone; Animals; Cyclooxygenase 1; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Intramolecular Oxidoreductases; Lipocalins; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Microsomes; Nitric Oxide Synthase Type II; Primary Cell Culture; Prostaglandin D2; Prostaglandin-E Synthases; Proto-Oncogene Proteins; RNA, Small Interfering; Thiophenes; Trans-Activators | 2012 |
Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages.
Topics: Acrylates; Angiotensin II; Animals; Anthracenes; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Imidazoles; Macrophages; Male; MAP Kinase Signaling System; Mice; Prostaglandin D2; Thiophenes; Up-Regulation | 2015 |