Page last updated: 2024-08-18

thiophenes and phencyclidine

thiophenes has been researched along with phencyclidine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's2 (12.50)18.2507
2000's7 (43.75)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailey, K; Gagné, DR; Pike, RK1
Casalotti, SO; Fauq, A; Kozikowski, AP; Krueger, KE; Tückmantel, W1
Radermecker, M1
Hamm, M; Klein, G; Matthys, H; Urbanek, R1
Hashimoto, A; Maeda, M; Nishikawa, T; Orita, K; Sasaki, S; Umezu, K; Yugami, T1
Arias, HR; Bhumireddy, P; Bouzat, C; Spitzmaul, G; Trudell, JR1
Kopjar, N; Petek, MJ; Radić, B; Vrdoljak, AL; Zeljezić, D1
Bloomquist, JR; Geldenhuys, WJ; Malan, SF; Van der Schyf, CJ1
Itoh, H; Kurachi, M; Matsuoka, T; Seo, T; Sumiyoshi, T; Tanaka, K; Tsunoda, M; Uehara, T1
Berend, S; Kopjar, N; Mladinić, M; Petek, MJ; Radić, B; Vrdoljak, AL; Zeljezić, D1
Fairlamb, AH; Frearson, JA; Gilbert, IH; Jones, DC; Patterson, S; Shanks, EJ; Wyatt, PG1
Kristie, TM; Liang, Y; Narayanan, A; Peng, H; Vogel, JL1
Mrsić, G; Petek, MJ; Vrdoljak, AL1
Fujita, Y; Futamura, T; Hashimoto, K; Kikuchi, T; Ohgi, Y; Yoshimi, N1
Parachikova, AI; Pedersen, CS; Plath, N; Sørensen, DB1
Anderson, WH; Bui, HH; Falcone, JF; Gleason, SD; Kato, A; Kuo, MS; Li, X; Stutz, PV; Thompson, LK; Valli, SN; Witkin, JM1

Trials

1 trial(s) available for thiophenes and phencyclidine

ArticleYear
[Protective effect of ketotifen and disodium cromoglycate in bronchial challenge tests with allergens (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Sep-19, Volume: 105, Issue:38

    Topics: Adolescent; Asthma; Child; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Dust; Female; Humans; Ketotifen; Male; Mites; Piperidines; Pollen; Thiophenes

1980

Other Studies

15 other study(ies) available for thiophenes and phencyclidine

ArticleYear
Identification of some analogs of the hallucinogen phencyclidine.
    Journal - Association of Official Analytical Chemists, 1976, Volume: 59, Issue:1

    Topics: Chromatography; Magnetic Resonance Spectroscopy; Mass Spectrometry; Morpholines; Phencyclidine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiophenes

1976
Design of an irreversible affinity ligand for the phencyclidine recognition site on N-methyl-D-aspartate-type glutamate receptors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Affinity Labels; Alkylation; Animals; Binding Sites; Binding, Competitive; Cattle; Dizocilpine Maleate; Female; Kinetics; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Thiocyanates; Thiophenes

1992
Inhibition of allergen-mediated histamine release from human cells by ketotifen and oxatomide. Comparison with other H1 antihistamines.
    Respiration; international review of thoracic diseases, 1981, Volume: 41, Issue:1

    Topics: Allergens; Cells, Cultured; Depression, Chemical; Dust; Histamine H1 Antagonists; Histamine Release; Humans; Ketotifen; Leukocytes; Lung; Piperazines; Piperidines; Pollen; Thiophenes

1981
Synthesis and evaluation of 1-(1-[5-(2'-[18F]fluoroethyl)-2-thienyl]-cyclohexyl)piperidine as a potential in vivo radioligand for the NMDA receptor-channel complex.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:7

    Topics: Animals; Fluorine Radioisotopes; Male; Phencyclidine; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thiophenes; Tissue Distribution; Tomography, Emission-Computed

1993
Molecular mechanisms and binding site location for the noncompetitive antagonist crystal violet on nicotinic acetylcholine receptors.
    Biochemistry, 2006, Feb-21, Volume: 45, Issue:7

    Topics: Allosteric Regulation; Amobarbital; Animals; Binding Sites; Fluorescent Dyes; Gentian Violet; Ion Channels; Models, Molecular; Nicotinic Agonists; Nicotinic Antagonists; Pentobarbital; Phencyclidine; Protein Binding; Protein Conformation; Quaternary Ammonium Compounds; Receptors, Nicotinic; Temperature; Tetracaine; Thiophenes; Torpedo; Tritium

2006
In vitro biological efficiency of tenocyclidine-TCP and its adamantane derivative TAMORF.
    Toxicology in vitro : an international journal published in association with BIBRA, 2006, Volume: 20, Issue:8

    Topics: Adamantane; Cell Survival; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chromosome Aberrations; Comet Assay; Erythrocytes; Gamma Rays; Humans; In Vitro Techniques; Lethal Dose 50; Leukocytes; Lymphocytes; Morpholines; Mutagens; Phencyclidine; Piperidines; Radiation-Protective Agents; Soman; Structure-Activity Relationship; Thiophenes; Trypan Blue

2006
Structure-activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor.
    Bioorganic & medicinal chemistry, 2007, Feb-01, Volume: 15, Issue:3

    Topics: Amines; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ion Channels; Male; Mice; Mice, Inbred ICR; Models, Molecular; Phencyclidine; Piperidines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptosomes; Thiophenes

2007
T-817MA, a novel neurotrophic compound, ameliorates phencyclidine-induced disruption of sensorimotor gating.
    Psychopharmacology, 2008, Volume: 197, Issue:3

    Topics: Acoustic Stimulation; Animals; Attention; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Inhibition, Psychological; Injections, Intraperitoneal; Male; Maleates; Neuroprotective Agents; Phencyclidine; Rats; Rats, Wistar; Reflex, Startle; Thiophenes

2008
Tenocyclidine treatment in soman-poisoned rats--intriguing results on genotoxicity versus protection.
    Acta biochimica Polonica, 2008, Volume: 55, Issue:1

    Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Comet Assay; Leukocytes; Male; Models, Chemical; Mutagens; Phencyclidine; Piperidines; Rats; Rats, Wistar; Soman; Thiophenes

2008
Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.
    ChemMedChem, 2009, Volume: 4, Issue:8

    Topics: Animals; Cell Line; Enzyme Inhibitors; Humans; NADH, NADPH Oxidoreductases; Phencyclidine; Piperidines; Structure-Activity Relationship; Thiophenes; Trypanocidal Agents; Trypanosoma brucei brucei

2009
Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency.
    Nature medicine, 2009, Volume: 15, Issue:11

    Topics: Animals; Cell Line, Transformed; Chromatin Immunoprecipitation; DNA Replication; Enzyme Activation; Ganglia; Gene Expression Regulation, Viral; Green Fluorescent Proteins; Herpesvirus 1, Human; Herpesvirus 3, Human; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Host Cell Factor C1; Humans; Lysine; Mice; Monoamine Oxidase Inhibitors; Mutation; Neurons; Pargyline; Phencyclidine; Piperidines; Promoter Regions, Genetic; Reaction Time; RNA, Small Interfering; Simplexvirus; Thiophenes; Time Factors; Transfection; Virus Replication

2009
Qualitative GC-MS assessment of TCP and TAMORF elimination in rats.
    Arhiv za higijenu rada i toksikologiju, 2010, Volume: 61, Issue:1

    Topics: Adamantane; Animals; Gas Chromatography-Mass Spectrometry; Male; Morpholines; Organophosphate Poisoning; Phencyclidine; Piperidines; Rats; Rats, Wistar; Thiophenes

2010
Effects of brexpiprazole, a novel serotonin-dopamine activity modulator, on phencyclidine-induced cognitive deficits in mice: a role for serotonin 5-HT1A receptors.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 124

    Topics: Animals; Cognition Disorders; Male; Mice; Mice, Inbred ICR; Phencyclidine; Quinolones; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine; Thiophenes

2014
PCP-induced deficits in murine nest building activity: employment of an ethological rodent behavior to mimic negative-like symptoms of schizophrenia.
    Behavioural brain research, 2014, Oct-15, Volume: 273

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzofurans; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Phencyclidine; Quinuclidines; Rotarod Performance Test; Schizophrenia; Schizophrenic Psychology; Social Behavior; Thiophenes

2014
Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8 Through Investigations of TARP γ-8 Null Mice§.
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:5

    Topics: Acetylcholine; Amphetamines; Animals; Biogenic Monoamines; Body Temperature; Brain; Calcium Channels; Central Nervous System Stimulants; Cyclic AMP; Excitatory Amino Acid Antagonists; Exploratory Behavior; Histamine; Hyperkinesis; Lipids; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Pentylenetetrazole; Phencyclidine; Receptors, AMPA; Seizures; Sulfonamides; Swimming; Thiophenes; Time Factors

2015