thiophenes has been researched along with pf 00868554 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beigelman, L; Blatt, L; Cai, H; Deval, J; Fan, B; Kao, CC; Ranjith-Kumar, CT; Smith, DB; Soulard, C; Yi, G | 1 |
| Appleby, TC; Bidgood, AM; Byun, D; Canales, E; Clarke, MO; Doerffler, E; Eng, S; Fenaux, M; Hashash, A; Krawczyk, SH; Lazerwith, SE; Leavitt, SA; Lee, YJ; Lew, W; Liu, Q; Mabery, EM; Matles, M; Mertzman, M; Morganelli, P; Murray, BP; Mwangi, J; Tian, Y; Watkins, WJ; Xu, L; Ye, H; Zhang, J | 1 |
| Douglas, MW; Eltahla, AA; Tay, E; White, PA | 1 |
| Deredge, D; Johnson, KA; Li, J; Wintrode, PL | 1 |
1 trial(s) available for thiophenes and pf 00868554
| Article | Year |
|---|---|
Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Dogs; Drug Resistance, Viral; Furans; Hepacivirus; Humans; Interferon-alpha; Male; Mutation; Polymorphism, Single Nucleotide; Pyrones; Rats; Rats, Sprague-Dawley; Ribavirin; RNA-Dependent RNA Polymerase; Thiophenes; Triazoles; Viral Nonstructural Proteins | 2013 |
3 other study(ies) available for thiophenes and pf 00868554
| Article | Year |
|---|---|
Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir.
Topics: Antiviral Agents; Binding Sites; Cell Line, Tumor; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Hepacivirus; Humans; Models, Molecular; Mutation; Pyrones; Replicon; RNA-Dependent RNA Polymerase; RNA, Viral; Templates, Genetic; Thiophenes; Triazoles | 2012 |
Cross-genotypic examination of hepatitis C virus polymerase inhibitors reveals a novel mechanism of action for thumb binders.
Topics: Antiviral Agents; Benzimidazoles; Benzofurans; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Genotype; Hepacivirus; Humans; Purines; Pyridazines; Pyrones; Recombinant Proteins; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Sulfonamides; Thiophenes; Triazoles; Viral Proteins | 2014 |
Hydrogen/Deuterium Exchange Kinetics Demonstrate Long Range Allosteric Effects of Thumb Site 2 Inhibitors of Hepatitis C Viral RNA-dependent RNA Polymerase.
Topics: Allosteric Regulation; Binding Sites; Deuterium Exchange Measurement; Furans; Hepacivirus; Kinetics; Pyrones; RNA-Dependent RNA Polymerase; RNA, Viral; Thiophenes; Triazoles; Viral Nonstructural Proteins | 2016 |