Page last updated: 2024-08-18

thiophenes and pentylenetetrazole

thiophenes has been researched along with pentylenetetrazole in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersen, ME; Jenkins, LJ; Jones, RA; Kurlansik, L; Mehl, RG1
Eigyo, M; Matsushita, A; Murata, S; Shindo, H; Takada, S1
Eigyo, M; Kawasaki, K; Matsushita, A; Murata, S; Sasatani, T; Shindo, H; Takada, S1
Araki, K; Nakanishi, M; Shiroki, M; Tahara, T; Tsumagari, T1
Nogas, JA; Sanchez, JP; Tinney, FJ1
Blackburn, T; Kennett, G; Middlemiss, D; Stean, T; Upton, N1
ABREU, BE; ALEXANDER, WM; BURCH, GR; WEAVER, LC1
Aladag, MA; Armutcu, F; Boluk, A; Gurel, A; Ilhan, A; Kocer, A1
Adhikari, AV; Kulandasamy, R; Stables, JP2
Anderson, WH; Bui, HH; Falcone, JF; Gleason, SD; Kato, A; Kuo, MS; Li, X; Stutz, PV; Thompson, LK; Valli, SN; Witkin, JM1
Moghimi, A; Roohbakhsh, A; Zandi, N; Zaniani, NR1
Ahmad, G; Imran, I; Rashid, U; Rasool, N; Rizwan, K; Sadiq, A; Zahoor, AF; Zubair, M1

Other Studies

13 other study(ies) available for thiophenes and pentylenetetrazole

ArticleYear
Sulfolane-induced convulsions in rodents.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 15, Issue:3

    Topics: Administration, Oral; Animals; Cyclic S-Oxides; Dogs; Drug Interactions; Guinea Pigs; Haplorhini; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Lethal Dose 50; Male; Mice; Pentobarbital; Pentylenetetrazole; Rabbits; Rats; Saimiri; Seizures; Sleep; Thiophenes; Time Factors

1976
Thienylpyrazoloquinolines with high affinity to benzodiazepine receptors: continuous shift from inverse agonist to agonist properties depending on the size of the alkyl substituent.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Chemical Phenomena; Chemistry; Diazepam; Drug Synergism; Male; Mice; Molecular Structure; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thiophenes

1989
A new thienylpyrazoloquinoline: a potent and orally active inverse agonist to benzodiazepine receptors.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:3

    Topics: Administration, Oral; Animals; Anticonvulsants; Indicators and Reagents; Male; Mice; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Thiophenes

1987
Studies on psychotropic drugs. 18. Synthesis and structure-activity relationships of 5-phenyl-1,3-dihydro-2H-thieno(2,3-e) (1,4) diazepin-2-ones.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:3

    Topics: Aggression; Animals; Azepines; Behavior, Animal; Central Nervous System; Depression, Chemical; Electroshock; Female; Humans; Ketones; Lethal Dose 50; Male; Mice; Motor Activity; Olfactory Bulb; Pentylenetetrazole; Rats; Sleep; Structure-Activity Relationship; Thiophenes; Tranquilizing Agents

1973
Synthesis and pharmacological evaluation of 2,3-dihydro-1H-thieno(2,3-e)(1,4)diazepines.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:6

    Topics: Animals; Anticonvulsants; Appetite; Azepines; Behavior, Animal; Central Nervous System; Drinking Behavior; Male; Pentylenetetrazole; Rats; Structure-Activity Relationship; Thiophenes; Tranquilizing Agents

1974
Studies on the role of 5-HT2C and 5-HT2B receptors in regulating generalised seizure threshold in rodents.
    European journal of pharmacology, 1998, Oct-16, Volume: 359, Issue:1

    Topics: Animals; Drug Interactions; Electric Stimulation; Indoles; Male; Mice; Pentylenetetrazole; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Seizures; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1998
The evaluation of two halogenated sulfolanes and pentylenetetrazol as antagonists to pentobarbital.
    The Journal of pharmacology and experimental therapeutics, 1956, Volume: 116, Issue:3

    Topics: Barbiturates; Humans; Pentobarbital; Pentylenetetrazole; Sulfones; Thiophenes

1956
Erdosteine ameliorates PTZ-induced oxidative stress in mice seizure model.
    Brain research bulletin, 2005, May-30, Volume: 65, Issue:6

    Topics: Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Convulsants; Disease Models, Animal; Drug Interactions; Female; Malondialdehyde; Mice; Nitric Oxide; Oxidative Stress; Pentylenetetrazole; Reaction Time; Seizures; Superoxide Dismutase; Thioglycolates; Thiophenes; Xanthine Oxidase

2005
Synthesis and anticonvulsant activity of some new bishydrazones derived from 3,4-dipropyloxythiophene.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Animals; Anticonvulsants; Electroshock; Hydrazones; Male; Mice; Pentylenetetrazole; Rotarod Performance Test; Seizures; Thiophenes

2009
A new class of anticonvulsants possessing 6 Hz activity: 3,4-dialkyloxy thiophene bishydrazones.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Animals; Anticonvulsants; Electroshock; Hydrazones; Male; Mice; Molecular Structure; Motor Activity; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiophenes

2009
Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8 Through Investigations of TARP γ-8 Null Mice§.
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:5

    Topics: Acetylcholine; Amphetamines; Animals; Biogenic Monoamines; Body Temperature; Brain; Calcium Channels; Central Nervous System Stimulants; Cyclic AMP; Excitatory Amino Acid Antagonists; Exploratory Behavior; Histamine; Hyperkinesis; Lipids; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Pentylenetetrazole; Phencyclidine; Receptors, AMPA; Seizures; Sulfonamides; Swimming; Thiophenes; Time Factors

2015
Protective effects of M8‑B, a TRPM8 antagonist, on febrile‑ and pentylenetetrazol‑induced seizures.
    Acta neurobiologiae experimentalis, 2019, Volume: 79, Issue:1

    Topics: Animals; Animals, Newborn; Anticonvulsants; Body Temperature; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Seizures, Febrile; Thiophenes; Time Factors; TRPM Cation Channels

2019
Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs.
    Bioorganic chemistry, 2019, Volume: 92

    Topics: Acetylcholinesterase; Animals; Anticonvulsants; Butyrylcholinesterase; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Electrophorus; Female; Horses; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiophenes

2019