thiophenes has been researched along with oxidopamine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 4 (16.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, KX; Jin, GZ; Sun, BC | 1 |
| de Boer, P; den Daas, I; Horn, AS; Rollema, H; Tepper, PG | 1 |
| de Vries, JB; den Daas, I; Horn, AS; Jansen, JM; Rollema, H; Swart, PJ; Tepper, PG | 1 |
| Bickford-Wimer, P; Strömberg, I | 1 |
| den Daas, I; Horn, AS; Tepper, PG | 1 |
| den Daas, I; Horn, AS; Rollema, H; Tepper, PG | 1 |
| De Vries, JB; Horn, AS; Tepper, PG; Van der Weide, J | 1 |
| De Vries, JB; Dubocovich, ML; Horn, AS; Krause, DN; Tepper, PG; Van der Weide, J | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Bankiewicz, KS; Belluzzi, JD; Domino, EF; May, JM; McAfee, DA | 1 |
| Asin, KE; Bednarz, L; Britton, DR; Giardina, WJ; Mahan, L; Mikusa, J; Nikkel, A; Shiosaki, K; Wismer, C | 1 |
| Asin, KE; Bayburt, EK; Britton, DR; DiDomenico, S; Hong, Y; Lin, CW; Michaelides, MR; Shiosaki, K | 1 |
| Bymaster, FP; Dreshfield-Ahmad, LJ; Hemrick-Luecke, SK; Nelson, DL; Shaw, JL; Thompson, L; Threlkeld, PG; Wong, DT | 1 |
| Jia, Z; Li, Y; Misra, HP; Zhu, H | 2 |
| Gerlach, M; Gruenblatt, E; Heindl, M; Lebsanft, H; Mayerhofer, A; Riederer, P; Scheller, DK; Schmidt, WJ | 1 |
| Mabrouk, OS; Marti, M; Morari, M; Volta, M | 1 |
| Li, Y; Liu, W; Sha, C; Sun, K; Wang, A; Wang, L | 1 |
| Alvarez-Fischer, D; Arias-Carrión, O; Borta, A; Djufri, M; Höglinger, GU; Keber, U; Oertel, WH; Ries, V; Scheller, D; Schwarting, RK; Windolph, A | 1 |
| Hiratochi, M; Ijiro, T; Kaidoh, K; Oana, F; Suzuki, T; Tsuchioka, A; Yamauchi, Y | 1 |
| Di Chiara, G; Espa, E; Fenu, S; Pisanu, A | 1 |
| Asanuma, M; Isooka, N; Kikuoka, R; Kitamura, Y; Miyazaki, I; Nakayama, E; Shin, K; Wada, K; Yamamoto, D | 1 |
| Alhakamy, NA; Anwer, MK; Bhattamisra, SK; Choudhury, H; Lim, WM; Md, S; Radhakrishnan, AK; Safian, NH; Shahzad, N; Shak, AT; Xi, LW | 1 |
| Abe-Takahashi, Y; Chiba, H; Higuchi, M; Kitta, T; Ouchi, M; Shinohara, N; Togo, M | 1 |
| Choe, HK; Choe, Y; Choi, JW; Choi, M; Jang, S; Kim, D; Kim, J; Kim, K; Moon, C; Park, I; Park, SH; Sun, W | 1 |
25 other study(ies) available for thiophenes and oxidopamine
| Article | Year |
|---|---|
Dual actions of (-)-stepholidine on dopamine receptor subtypes after substantia nigra lesion.
Topics: Animals; Apomorphine; Berberine; Dopamine Antagonists; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stereoisomerism; Stereotyped Behavior; Substantia Nigra; Tetrahydronaphthalenes; Thiophenes | 1992 |
Orally active carbamate prodrugs of the selective dopamine agonist N-0437: in-vivo activities in the 6-OHDA turning model and in-vitro activities.
Topics: Administration, Oral; Animals; Behavior, Animal; Carbamates; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Dopamine Agents; Hydrolysis; Hydroxydopamines; Male; Oxidopamine; Prodrugs; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Thiophenes | 1991 |
Pharmacological profile of non-hydroxylated and ether derivatives of the potent D2-selective agonist N-0437.
Topics: Animals; Brain; Dialysis; Dopamine Agents; Ethers; Hydroxydopamines; Hydroxylation; Male; Models, Biological; Molecular Structure; Motor Activity; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Rotation; Tetrahydronaphthalenes; Thiophenes | 1991 |
Effects of locally applied D1 and D2 agonists on striatal neurons with 6-OHDA and pertussis toxin lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caudate Nucleus; Corpus Striatum; Dopamine Agents; Female; Nervous System Diseases; Neurons; Oxidopamine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotaxic Techniques; Sympathectomy, Chemical; Tetrahydronaphthalenes; Thiophenes; Up-Regulation; Virulence Factors, Bordetella | 1991 |
Improvement of the oral bioavailability of the selective dopamine agonist N-0437 in rats: the in vitro and in vivo activity of eight ester prodrugs.
Topics: Animals; Behavior, Animal; Biological Availability; Dopamine Agents; Dose-Response Relationship, Drug; Half-Life; Hydrolysis; Hydroxydopamines; Male; Naphthalenes; Oxidopamine; Prodrugs; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Stereotyped Behavior; Tetrahydronaphthalenes; Thiophenes | 1990 |
Transdermal administration of the dopamine agonist N-0437 and seven ester prodrugs: comparison with oral administration in the 6-OHDA turning model.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Dopamine; Dopamine Agents; Hydroxydopamines; Male; Oxidopamine; Prodrugs; Rats; Rats, Inbred Strains; Synapses; Tetrahydronaphthalenes; Thiophenes | 1990 |
The effects of kainic acid and 6-hydroxydopamine lesions, metal ions and GTP on in vitro binding of the D-2 dopamine agonist, [3H]N-0437, to striatal membranes.
Topics: Animals; Corpus Striatum; Guanosine Triphosphate; Hydroxydopamines; In Vitro Techniques; Kainic Acid; Male; Metals; Naphthalenes; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sympathectomy, Chemical; Tetrahydronaphthalenes; Thiophenes | 1987 |
N-0437: a selective D-2 dopamine receptor agonist in in vitro and in vivo models.
Topics: Acetylcholine; Animals; Brain; Calcium; Cattle; Corpus Striatum; Dopamine; Electric Stimulation; Hydroxydopamines; In Vitro Techniques; Male; Mice; Motor Activity; Naphthalenes; Oxidopamine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Stereotyped Behavior; Sympathectomy, Chemical; Tetrahydronaphthalenes; Thiophenes | 1988 |
Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Dopamine; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Neurotransmitter Uptake Inhibitors; Norepinephrine; Oxidopamine; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes | 1994 |
N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Bromocriptine; Disease Models, Animal; Dominance, Cerebral; Dopamine Agents; Female; Injections, Intramuscular; Macaca nemestrina; Male; Oxazines; Oxidopamine; Parkinson Disease, Secondary; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Substantia Nigra; Tetrahydronaphthalenes; Thiophenes | 1994 |
Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431.
Topics: Animals; Behavior, Animal; Benzazepines; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Oxidopamine; Prodrugs; Pyridines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Seizures; Sympathectomy, Chemical; Tetrahydronaphthalenes; Thiophenes | 1996 |
Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo.
Topics: Adenylyl Cyclases; Animals; Benzazepines; Binding, Competitive; Cell Membrane; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Fishes; Mice; Molecular Structure; Oxidopamine; Parkinson Disease, Secondary; Quinolones; Receptors, Dopamine; Retina; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Tritium; Yohimbine | 1997 |
Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors.
Topics: Animals; Biogenic Monoamines; Carrier Proteins; Cell Line; Cyclohexanols; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase; Nerve Tissue Proteins; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; p-Chloroamphetamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Sympatholytics; Symporters; Thiophenes; Venlafaxine Hydrochloride | 2001 |
Potent induction of total cellular GSH and NQO1 as well as mitochondrial GSH by 3H-1,2-dithiole-3-thione in SH-SY5Y neuroblastoma cells and primary human neurons: protection against neurocytotoxicity elicited by dopamine, 6-hydroxydopamine, 4-hydroxy-2-no
Topics: Aldehydes; Antioxidants; Cell Line, Tumor; Cells, Cultured; Dopamine; Glutathione; Humans; Hydrogen Peroxide; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiones; Thiophenes | 2008 |
Continuous versus pulsatile administration of rotigotine in 6-OHDA-lesioned rats: contralateral rotations and abnormal involuntary movements.
Topics: Adrenergic Agents; Animals; Dopamine Agonists; Dyskinesia, Drug-Induced; Dyskinesias; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Tetrahydronaphthalenes; Thiophenes | 2008 |
Stimulation of delta opioid receptors located in substantia nigra reticulata but not globus pallidus or striatum restores motor activity in 6-hydroxydopamine lesioned rats: new insights into the role of delta receptors in parkinsonism.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzamides; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hindlimb Suspension; Male; Microdialysis; Motor Activity; Oxidopamine; Parkinsonian Disorders; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substantia Nigra; Thiophenes; Time Factors | 2008 |
Cruciferous nutraceutical 3H-1,2-dithiole-3-thione protects human primary astrocytes against neurocytotoxicity elicited by MPTP, MPP(+), 6-OHDA, HNE and acrolein.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acrolein; Aldehydes; Astrocytes; Brassicaceae; Cells, Cultured; Glutathione; Glutathione Reductase; Humans; NAD(P)H Dehydrogenase (Quinone); Oxidants; Oxidopamine; RNA, Messenger; Thiones; Thiophenes | 2009 |
Preparation of rotigotine-loaded microspheres and their combination use with L-DOPA to modify dyskinesias in 6-OHDA-lesioned rats.
Topics: Animals; Dopamine Agonists; Drug Carriers; Drug Therapy, Combination; Dyskinesias; Levodopa; Male; Microspheres; Oxidopamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thiophenes | 2012 |
A new dopaminergic nigro-olfactory projection.
Topics: Animals; Dopamine; Dopamine Agonists; Immunohistochemistry; Male; Neural Pathways; Neural Stem Cells; Neuroanatomical Tract-Tracing Techniques; Neurogenesis; Neuronal Tract-Tracers; Neurons; Olfaction Disorders; Olfactory Bulb; Oxidopamine; Parkinsonian Disorders; Rats, Wistar; Substantia Nigra; Tetrahydronaphthalenes; Thiophenes | 2015 |
Duration of drug action of dopamine D2 agonists in mice with 6-hydroxydopamine-induced lesions.
Topics: Animals; Antiparkinson Agents; Apomorphine; Azepines; Benzothiazoles; Cabergoline; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Ergolines; Indoles; Injections, Intraventricular; Male; Mice; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pramipexole; Quinolines; Receptors, Dopamine D2; Tetrahydronaphthalenes; Thiophenes | 2015 |
In vivo dopamine agonist properties of rotigotine: Role of D1 and D2 receptors.
Topics: Animals; Behavior, Animal; Benzothiazoles; Dopamine; Dopamine Agonists; Gene Expression Regulation; Male; Oxidopamine; Pramipexole; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Tetrahydronaphthalenes; Thiophenes | 2016 |
Dopaminergic neuroprotective effects of rotigotine via 5-HT1A receptors: Possibly involvement of metallothionein expression in astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Dopamine Agonists; Female; Male; Metallothionein; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Antagonists; Tetrahydronaphthalenes; Thiophenes | 2020 |
Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease.
Topics: Administration, Intranasal; alpha-Synuclein; Animals; Blood-Brain Barrier; Cell Line, Tumor; Chitosan; Disease Models, Animal; Dopamine Agonists; Drug Carriers; Female; Haloperidol; Humans; Male; Nanoparticles; Neurons; Oxidopamine; Parkinson Disease, Secondary; Particle Size; Rats; Tetrahydronaphthalenes; Thiophenes; Toxicity Tests, Acute | 2020 |
Mechanisms of D1/D2-like dopaminergic agonist, rotigotine, on lower urinary tract function in rat model of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Female; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tetrahydronaphthalenes; Thiophenes; Urinary Bladder | 2022 |
Pharmacological Rescue with SR8278, a Circadian Nuclear Receptor REV-ERBα Antagonist as a Therapy for Mood Disorders in Parkinson's Disease.
Topics: Animals; Humans; Isoquinolines; Mice; Mood Disorders; Neurodegenerative Diseases; Nuclear Receptor Subfamily 1, Group D, Member 1; Oxidopamine; Parkinson Disease; Quality of Life; Thiophenes; Tyrosine 3-Monooxygenase | 2022 |