Page last updated: 2024-08-18

thiophenes and osteoprotegerin

thiophenes has been researched along with osteoprotegerin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's8 (57.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Biskobing, DM; Downs, R; Novy, AM1
Geusens, P; Reid, D1
Atkins, GJ; Findlay, DM; Halbout, P; Welldon, KJ1
Masuda, H; Tanaka, S1
Atwa, S; Brennan, TC; Conigrave, AD; Green, W; Mason, RS; Rybchyn, MS1
Goëb, V; Trouvin, AP1
Brzeziańska, E; Cegłowska, A; Liberski, PP; Rieske, P; Sewerynek, E; Stêpień-Kłos, W; Stuss, M1
Cui, J; Geng, D; Liu, X; Shao, H; Xu, Y; Yang, H; Yu, L; Zhang, W; Zhu, S1
Khlusov, IA; Nechaev, KA; Vengerovskiĭ, AI1
Jędrzejczyk, S; Król, I; Sewerynek, E; Stępień-Kłos, W; Stuss, M1
Akpınar, A; Göze, F; Karakan, NC; Poyraz, Ö1
Chen, X; Geng, T; Guo, H; Jin, Q; Sun, S; Wang, B; Zhang, S1
Chen, X; Geng, T; Guo, H; Jin, Q; Sun, S; Yu, H; Zhang, S; Zheng, M1
da Silva, HDP; Duarte, PM; Franco, BDST; Malta, FS; Marins, LM; Miranda, TS; Nani, EP; Napimoga, MH1

Reviews

5 review(s) available for thiophenes and osteoprotegerin

ArticleYear
Novel therapeutic options for osteoporosis.
    Current opinion in rheumatology, 2002, Volume: 14, Issue:4

    Topics: Animals; Controlled Clinical Trials as Topic; Diphosphonates; Disease Models, Animal; Evidence-Based Medicine; Fractures, Spontaneous; Glycoproteins; Humans; Ibandronic Acid; Imidazoles; Norpregnenes; Osteoporosis; Osteoprotegerin; Piperidines; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Selective Estrogen Receptor Modulators; Thiophenes; Zoledronic Acid

2002
Newer drug treatments: their effects on fracture prevention.
    Best practice & research. Clinical rheumatology, 2005, Volume: 19, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density; Bone Density Conservation Agents; Calcitonin; Denosumab; Diphosphonates; Fractures, Bone; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibandronic Acid; Imidazoles; Organometallic Compounds; Osteoporosis; Osteoprotegerin; Parathyroid Hormone; RANK Ligand; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Thiophenes; Zoledronic Acid

2005
[Drugs under development for osteoporosis ].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Cathepsin K; Cathepsins; Denosumab; Diphosphonates; Drug Design; Humans; Ibandronic Acid; Imidazoles; Organometallic Compounds; Osteoporosis; Osteoprotegerin; RANK Ligand; Selective Estrogen Receptor Modulators; Teriparatide; Thiophenes

2009
Receptor activator of nuclear factor-κB ligand and osteoprotegerin: maintaining the balance to prevent bone loss.
    Clinical interventions in aging, 2010, Nov-19, Volume: 5

    Topics: Aging; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Denosumab; Female; Humans; Male; Mice; NF-kappa B; Organometallic Compounds; Osteoblasts; Osteoclasts; Osteoporosis; Osteoprotegerin; RANK Ligand; Rats; Thiophenes

2010
[Molecular mechanisms of action of bisphosphonates and strontium ranelate].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:9

    Topics: Apoptosis; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Gene Expression Regulation; Geranyltranstransferase; Humans; Osteoblasts; Osteoclasts; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction; Thiophenes; Wnt Proteins

2014

Trials

1 trial(s) available for thiophenes and osteoprotegerin

ArticleYear
Assessment of OPG/RANK/RANKL gene expression levels in peripheral blood mononuclear cells (PBMC) after treatment with strontium ranelate and ibandronate in patients with postmenopausal osteoporosis.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:5

    Topics: Aged; Aged, 80 and over; Bone Density; Bone Density Conservation Agents; Calcium, Dietary; Cholecalciferol; Combined Modality Therapy; Dietary Supplements; Diphosphonates; Female; Gene Expression Regulation; Humans; Ibandronic Acid; Leukocytes, Mononuclear; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; RNA, Messenger; Thiophenes

2013

Other Studies

8 other study(ies) available for thiophenes and osteoprotegerin

ArticleYear
Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:4

    Topics: Apoptosis; Bone Density Conservation Agents; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Organometallic Compounds; Osteoblasts; Osteocytes; Osteoprotegerin; Phenotype; Thiophenes

2009
Osteoblasts play key roles in the mechanisms of action of strontium ranelate.
    British journal of pharmacology, 2009, Volume: 157, Issue:7

    Topics: Anabolic Agents; Bone Density Conservation Agents; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Gene Knockdown Techniques; Humans; Organometallic Compounds; Osteoblasts; Osteoclasts; Osteoprotegerin; RANK Ligand; Receptors, Calcium-Sensing; RNA, Messenger; RNA, Small Interfering; Thiophenes

2009
Strontium ranelate inhibits titanium-particle-induced osteolysis by restraining inflammatory osteoclastogenesis in vivo.
    Acta biomaterialia, 2014, Volume: 10, Issue:11

    Topics: Acid Phosphatase; Animals; Inflammation; Interleukin-1beta; Isoenzymes; Male; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; RNA, Messenger; Skull; Staining and Labeling; Tartrate-Resistant Acid Phosphatase; Thiophenes; Titanium; Tumor Necrosis Factor-alpha; X-Ray Microtomography

2014
Assessment of OPG, RANKL, bone turnover markers serum levels and BMD after treatment with strontium ranelate and ibandronate in patients with postmenopausal osteoporosis.
    Endokrynologia Polska, 2016, Volume: 67, Issue:2

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Bone Remodeling; Diphosphonates; Drug Therapy, Combination; Female; Humans; Ibandronic Acid; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Osteoprotegerin; RANK Ligand; Thiophenes

2016
Investigating the Effects of Systemically Administered Strontium Ranelate on Alveolar Bone Loss Histomorphometrically and Histopathologically on Experimental Periodontitis in Rats.
    Journal of periodontology, 2017, Volume: 88, Issue:2

    Topics: Alkaline Phosphatase; Alveolar Bone Loss; Animals; Biomarkers; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-1beta; Male; Osteoclasts; Osteoprotegerin; Periodontitis; Random Allocation; RANK Ligand; Rats; Rats, Wistar; Thiophenes

2017
Strontium ranelate reduces the progression of titanium particle-induced osteolysis by increasing the ratio of osteoprotegerin to receptor activator of nuclear factor-κB ligand in vivo.
    Molecular medicine reports, 2018, Volume: 17, Issue:3

    Topics: Administration, Oral; Alloys; Animals; Biomarkers; Bone Density Conservation Agents; Bone-Implant Interface; Dose-Response Relationship, Drug; Female; Gene Expression; Mice; Mice, Inbred C57BL; Osteolysis; Osteoprotegerin; Particulate Matter; Prostheses and Implants; Prosthesis Failure; RANK Ligand; Thiophenes; Tibia; Titanium

2018
Effects of strontium ranelate on wear particle‑induced aseptic loosening in female ovariectomized mice.
    Molecular medicine reports, 2018, Volume: 18, Issue:2

    Topics: Aged; Alendronate; Animals; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Female; Humans; Mice; Osteocalcin; Osteoclasts; Osteogenesis; Osteolysis; Osteoporosis; Osteoprotegerin; Prosthesis Failure; Thiophenes

2018
Effects of strontium ranelate on ligature-induced periodontitis in estrogen-deficient and estrogen-sufficient rats.
    Journal of periodontal research, 2020, Volume: 55, Issue:1

    Topics: Alveolar Bone Loss; Animals; Estrogens; Osteocalcin; Osteopontin; Osteoprotegerin; Ovariectomy; Periodontitis; RANK Ligand; Rats; Rats, Wistar; Thiophenes

2020