thiophenes has been researched along with org 9935 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furman, BL; Pyne, NJ; Shafiee-Nick, R | 1 |
| El-Metwally, M; Furman, BL; Pyne, NJ; Shafiee-Nick, R | 1 |
| Blease, K; Burke-Gaffney, A; Hellewell, PG | 1 |
| Conti, M; Hanssen, RG; Hirsch, B; Hsueh, AJ; Kloosterboer, HJ; Tsafriri, A; Van de Kant, M; Wiersma, A | 1 |
| Adcock, IM; Barnes, PJ; Robichaud, A; Seybold, J; Wright, LC | 1 |
| Conti, M; DePaolo, LV; Jensen, JT; Schwinof, KM; Stouffer, RL; Zelinski-Wooten, MB | 1 |
| Adriaenssens, T; Albano, C; Bourgain, C; Cortvrindt, R; Devroey, P; Nogueira, D; Smitz, J | 1 |
| Cortvrindt, R; De Matos, DG; Nogueira, D; Smitz, J; Vanhoutte, L | 1 |
| Jensen, JT; Schwinof, KM; Stouffer, RL; Vance, JE; Zelinski-Wooten, MB | 1 |
| Cortvrindt, R; Everaerdt, B; Nogueira, D; Smitz, J | 1 |
| Fanton, JW; Jensen, JT; Stanley, JE; Stouffer, RL; Zelinski, MB | 1 |
| Romero, S; Smitz, J | 1 |
| Jensen, JT; Stanley, JE; Stouffer, RL; Zelinski, MB | 1 |
| Hsueh, AJ; Li, M; Li, R; Liu, P; Qiao, J; Yan, J; Yan, LY; Yu, Y; Zhao, Y | 1 |
14 other study(ies) available for thiophenes and org 9935
| Article | Year |
|---|---|
Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Guanidines; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazines; Pyridazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Thiophenes | 1995 |
The effect of selective phosphodiesterase inhibitors on plasma insulin concentrations and insulin secretion in vitro in the rat.
Topics: Animals; Blood Glucose; Blood Pressure; Cardiotonic Agents; Heart Rate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organic Chemicals; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Thiophenes | 1997 |
Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Albuterol; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Endothelium, Vascular; Eosinophils; Humans; Lung; Neutrophils; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Thiophenes; Tumor Necrosis Factor-alpha | 1998 |
Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Contraceptive Agents, Female; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Estrus; Female; Fertilization; Heart Rate; Hypoxanthine; Isoenzymes; Meiosis; Menotropins; Mice; Mice, Inbred C57BL; Milrinone; Oogenesis; Ovarian Follicle; Ovulation; Ovulation Induction; Phosphodiesterase Inhibitors; Pregnancy; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Rolipram; Second Messenger Systems; Substrate Specificity; Thiophenes | 1998 |
Phosphodiesterase expression in human epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Cell Line; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 1; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Lung; Phosphodiesterase Inhibitors; Purinones; Pyrrolidinones; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Thiophenes | 1998 |
Phosphodiesterase 3 inhibitors selectively block the spontaneous resumption of meiosis by macaque oocytes in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Feasibility Studies; Female; Macaca mulatta; Meiosis; Milrinone; Oocytes; Phosphodiesterase Inhibitors; Quinolones; Rolipram; Thiophenes | 2002 |
Human oocytes reversibly arrested in prophase I by phosphodiesterase type 3 inhibitor in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Meiosis; Oocytes; Ovarian Follicle; Prophase; Random Allocation; RNA, Messenger; Thiophenes | 2003 |
Effect of phosphodiesterase type 3 inhibitor on developmental competence of immature mouse oocytes in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blastocyst; Cells, Cultured; Chromatin; Cyclic Nucleotide Phosphodiesterases, Type 3; Embryonic and Fetal Development; Female; Fertilization in Vitro; Male; Meiosis; Mice; Mice, Inbred Strains; Oocytes; Phosphodiesterase Inhibitors; Thiophenes | 2003 |
The phosphodiesterase 3 inhibitor ORG 9935 inhibits oocyte maturation during gonadotropin-stimulated ovarian cycles in rhesus macaques.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Gonadotropins; Macaca mulatta; Meiosis; Menstrual Cycle; Oocytes; Thiophenes | 2005 |
Effects of long-term in vitro exposure to phosphodiesterase type-3 inhibitors on follicle and oocyte development.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Follicular Phase; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microscopy, Fluorescence; Oocytes; Oogenesis; Ovarian Follicle; Ovulation; Quinolones; Thiophenes; Time Factors | 2005 |
The phosphodiesterase 3 inhibitor ORG 9935 inhibits oocyte maturation in the naturally selected dominant follicle in rhesus macaques.
Topics: Animals; Contraceptive Agents, Female; Female; Macaca mulatta; Meiosis; Oocytes; Ovulation; Phosphodiesterase 3 Inhibitors; Phosphodiesterase Inhibitors; Thiophenes | 2008 |
Improvement of in vitro culture of mouse cumulus-oocyte complexes using PDE3-inhibitor followed by meiosis induction with epiregulin.
Topics: Animals; Cell Survival; Chorionic Gonadotropin; Culture Media, Conditioned; Cumulus Cells; Epidermal Growth Factor; Epiregulin; Estradiol; Female; Meiosis; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Oocytes; Organ Culture Techniques; Ovarian Follicle; Phosphodiesterase 3 Inhibitors; Progesterone; Reproductive Control Agents; Thiophenes | 2010 |
Evaluation of the phosphodiesterase 3 inhibitor ORG 9935 as a contraceptive in female macaques: initial trials.
Topics: Animals; Contraceptive Agents, Female; Dose-Response Relationship, Drug; Female; Fertility; Macaca fascicularis; Male; Phosphodiesterase Inhibitors; Pregnancy; Thiophenes; Treatment Outcome | 2010 |
The role of cilostazol, a phosphodiesterase 3 inhibitor, on oocyte maturation and subsequent pregnancy in mice.
Topics: Animals; Cells, Cultured; Cilostazol; Contraceptive Agents, Female; Dose-Response Relationship, Drug; Drug Administration Schedule; Embryo, Mammalian; Female; Fertilization; Male; Meiosis; Mice; Mice, Inbred ICR; Oocytes; Oogenesis; Phosphodiesterase 3 Inhibitors; Pregnancy; Tetrazoles; Thiophenes | 2012 |