Page last updated: 2024-08-18

thiophenes and naphthalimides

thiophenes has been researched along with naphthalimides in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Abradelo, C; Báñez-Coronel, M; Braña, MF; Cacho, M; de Pascual-Teresa, B; Domínguez, MT; García, MA; Lacal, JC; Pozuelo, JM; Ramos, A; Rey-Stolle, MF; Yuste, M1
Cai, YJ; Chen, Y; Ding, J; Geng, MY; Huang, M; Luo, HB; Miao, ZH; Qian, XH; Qin, YX; Shen, X; Xu, YF; Yang, F; Zhu, H1
Ding, J; Feng, JM; Miao, ZH; Zhang, XW; Zhu, H1
Cai, YJ; Ding, J; Feng, JM; Huang, M; Lu, JJ; Miao, ZH; Qian, XH; Tong, LJ; Xu, YF; Zhang, ZX; Zhu, H1
Carpentier, S; Courtoy, PJ; Gueuning, MA; Horman, S; Hue, L; Hussain, N; Miranda, L; Ozkan, Y; Platek, A; Rider, MH; Sid, B; Vertommen, D1
Ott, I; Qian, X; Xu, Y1
Dai, G; Jiang, H; Jin, Z; Liu, S; Lu, J; Wang, C; Wu, J1
Jia, Y; Lee, JH; Lee, SJ; Seo, WD; Wu, C1
Johnson, SW; Munhall, AC; Yang, W1

Other Studies

9 other study(ies) available for thiophenes and naphthalimides

ArticleYear
New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Adenine; Amides; Animals; Cell Line, Tumor; DNA; Drug Screening Assays, Antitumor; Furans; Humans; Imides; Intercalating Agents; Isoquinolines; Mice; Mice, Nude; Models, Molecular; Naphthalimides; Neoplasm Transplantation; Organophosphonates; Structure-Activity Relationship; Thiophenes; Transplantation, Heterologous

2004
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:2

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Division; Cell Proliferation; Cytochromes c; DNA Topoisomerases, Type II; Enzyme Inhibitors; Female; Flow Cytometry; G2 Phase; Humans; Imides; In Situ Nick-End Labeling; Isoquinolines; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Naphthalimides; Organophosphonates; Poly(ADP-ribose) Polymerases; Sarcoma, Experimental; Thiophenes; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2007
Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity.
    Cancer biology & therapy, 2008, Volume: 7, Issue:11

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Enzyme Inhibitors; Flow Cytometry; HSP90 Heat-Shock Proteins; Humans; Leupeptins; Naphthalimides; Proteasome Endopeptidase Complex; Protein Kinases; Thiophenes; Time Factors; Topoisomerase II Inhibitors; Ubiquitin

2008
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:11

    Topics: Adenine; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Breaks, Double-Stranded; DNA-Binding Proteins; Flow Cytometry; Fluorescent Antibody Technique; G2 Phase; HCT116 Cells; Humans; Naphthalimides; Organophosphonates; Protein Serine-Threonine Kinases; RNA, Small Interfering; Signal Transduction; Thiophenes; Transfection; Tumor Suppressor Proteins

2009
AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells.
    Biochemical and biophysical research communications, 2010, Jun-04, Volume: 396, Issue:3

    Topics: Actin Depolymerizing Factors; Actins; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line; Cytoskeleton; Dogs; Epithelial Cells; Naphthalimides; Osmotic Pressure; Paxillin; Phosphorylation; Pyrones; rho-Associated Kinases; Ribonucleotides; Saline Solution, Hypertonic; Thiophenes

2010
Fluorescence properties and antiproliferative effects of mono-, bis-, and tris- thiophenylnaphthalimides: results of a comparative pilot study.
    Journal of photochemistry and photobiology. B, Biology, 2011, Oct-05, Volume: 105, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Microscopy, Fluorescence; Naphthalimides; Pilot Projects; Spectrometry, Fluorescence; Thiophenes

2011
Novel fluorescent 1,8-naphthalimide derivatives containing thiophene and pyrazole moieties: synthesis by direct C-H arylation and evaluation of photophysical and electrochemical properties.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Jan-03, Volume: 117

    Topics: Benzene Derivatives; Electrochemistry; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Naphthalimides; Photochemistry; Pyrazoles; Quantum Theory; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Thiophenes

2014
Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: AMP-Activated Protein Kinases; Apigenin; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cyclic AMP Response Element-Binding Protein; Enzyme Activators; Forkhead Box Protein O1; Forkhead Transcription Factors; Gluconeogenesis; Glucose; Glucose Transporter Type 4; Glucosides; Hep G2 Cells; Histone Deacetylases; Humans; Insulin Resistance; Metformin; Naphthalimides; Phosphorylation; Pyrones; Thiophenes; Transcription Factors

2015
Dopamine Evokes a Trace Amine Receptor-dependent Inward Current that is Regulated by AMP Kinase in Substantia Nigra Dopamine Neurons.
    Neuroscience, 2020, 02-10, Volume: 427

    Topics: AMP-Activated Protein Kinases; Animals; Benzamides; Benzazepines; Benzimidazoles; Biphenyl Compounds; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Naphthalimides; Pars Compacta; Patch-Clamp Techniques; Piperazines; Pyrazoles; Pyrimidines; Pyrones; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Sulpiride; Thiophenes

2020