Page last updated: 2024-08-18

thiophenes and n-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide

thiophenes has been researched along with n-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (75.00)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Aguilar, HR; Bachoo, RM; Frantz, DE; Hsieh, J; Hsu, T; Li, P; Schneider, JW; Zhang, L1
Birnbaum, SG; Eisch, AJ; Hsieh, J; Jiang, Y; Kim, MS; Petrik, D; Powell, CM1
Bettio, LE; Christie, BR; Gil-Mohapel, J; Gopalakrishnan, K; Hanley, RP; Kennedy, S; O'Rourke, NF; Patten, AR; Rodrigues, AL; Wulff, J1
Chaing, S; Fannon-Pavlich, MJ; Galinato, MH; Ghofranian, A; Heyser, C; Janda, KD; Joea, A; Koob, GF; Lockner, JW; Luikart, BW; Mandyam, CD; Navarro, AI; Sobieraj, JC; Somkuwar, SS; Staples, MC1
Ali, A; Ashraf, M; Hu, H; Maienschein-Cline, M; Tang, Y; Wang, Y; Xuan, W1
Chen, JJ; Chen, LF; Si, SY; Wang, Z; Zhao, XL1
Lee, C; Robinson, M; Willerth, SM1
Battiprolu, PK; De Marchi, U; Dioum, EHM; Hajibeigi, A; Heikkila, E; Öz, OK; Pujol, JB; Savoia, C1
Bewick, GA; Fonseca Pedro, P; Hayee, B; Pavlidis, P; Tsakmaki, A1
Avchalumov, Y; Herman, MA; Janda, KD; Kharidia, KM; Lockner, JW; Mandyam, CD; Roberto, M; Staples, MC1
Chang, HC; Li, H; Li, Q; Li, Y; Ou, J; Peng, C; Tang, YC; Wu, P; Xu, N1

Other Studies

12 other study(ies) available for thiophenes and n-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide

ArticleYear
Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression.
    Differentiation; research in biological diversity, 2011, Volume: 81, Issue:4

    Topics: Animals; Astrocytes; Cell Dedifferentiation; Cell Proliferation; Cells, Cultured; Cellular Reprogramming; Epigenesis, Genetic; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioma; Histone Deacetylase Inhibitors; Isoxazoles; Mice; Neoplastic Stem Cells; Neurogenesis; Neurons; Thiophenes; Tumor Suppressor Proteins

2011
Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:8

    Topics: Animals; Blood-Brain Barrier; Cell Proliferation; Dendritic Cells; Dentate Gyrus; Hippocampus; Isoxazoles; Maze Learning; MEF2 Transcription Factors; Memory; Mice; Mice, Transgenic; Myogenic Regulatory Factors; Neural Stem Cells; Neurogenesis; Thiophenes

2012
ISX-9 can potentiate cell proliferation and neuronal commitment in the rat dentate gyrus.
    Neuroscience, 2016, 09-22, Volume: 332

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Cell Proliferation; Central Nervous System Agents; Corticosterone; Dentate Gyrus; Drug Evaluation, Preclinical; Immunohistochemistry; Isoxazoles; Male; Molecular Structure; Neurogenesis; Neurons; Rats, Sprague-Dawley; Stress, Psychological; Thiophenes

2016
Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.
    Nature neuroscience, 2017, Volume: 20, Issue:5

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cognitive Dysfunction; Corpus Striatum; Epigenomics; Gene Expression; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Humans; Huntingtin Protein; Huntington Disease; Induced Pluripotent Stem Cells; Isoxazoles; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurogenesis; Neurons; Peptides; Signal Transduction; Thiophenes

2017
A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse.
    Molecular psychiatry, 2018, Volume: 23, Issue:3

    Topics: Animals; Brain; Dentate Gyrus; Drug-Seeking Behavior; Individuality; Isoxazoles; Learning; Male; Memory; Methamphetamine; Neurogenesis; Neurons; Rats; Rats, Wistar; Recurrence; Self Administration; Substance-Related Disorders; Thiophenes

2018
Cardiac Progenitors Induced from Human Induced Pluripotent Stem Cells with Cardiogenic Small Molecule Effectively Regenerate Infarcted Hearts and Attenuate Fibrosis.
    Shock (Augusta, Ga.), 2018, Volume: 50, Issue:6

    Topics: Animals; Cell Differentiation; Disease Models, Animal; Fibrosis; Humans; Induced Pluripotent Stem Cells; Isoxazoles; Mice; Myocardial Infarction; Myocytes, Cardiac; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stem Cell Transplantation; Thiophenes

2018
T63 inhibits osteoclast differentiation through regulating MAPKs and Akt signaling pathways.
    European journal of pharmacology, 2018, Sep-05, Volume: 834

    Topics: Actins; Animals; Cell Differentiation; Enzyme Activation; Gene Expression Regulation; Isoxazoles; MAP Kinase Signaling System; Mice; Osteoblasts; Osteoclasts; Proto-Oncogene Proteins c-akt; RANK Ligand; RAW 264.7 Cells; Thiophenes

2018
Direct Reprogramming of Glioblastoma Cells into Neurons Using Small Molecules.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cellular Reprogramming; Cellular Reprogramming Techniques; Colforsin; Diamines; Glioblastoma; Heterocyclic Compounds, 4 or More Rings; Homeodomain Proteins; Humans; Isoxazoles; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; POU Domain Factors; Pyridines; Pyrimidines; Thiazoles; Thiophenes; Up-Regulation

2018
Isx9 Regulates Calbindin D28K Expression in Pancreatic β Cells and Promotes β Cell Survival and Function.
    International journal of molecular sciences, 2018, Aug-27, Volume: 19, Issue:9

    Topics: Animals; Calbindins; Cell Line, Tumor; Cell Survival; Diabetes Mellitus, Experimental; Gene Expression Regulation, Neoplastic; Humans; Insulin-Secreting Cells; Islets of Langerhans; Islets of Langerhans Transplantation; Isoxazoles; Mice, Inbred NOD; Mice, SCID; NFATC Transcription Factors; Rats; Thiophenes

2018
ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoids.
    Molecular metabolism, 2020, Volume: 34

    Topics: Animals; Cell Differentiation; Cell Lineage; Enteroendocrine Cells; Humans; Intestines; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organ Culture Techniques; Organoids; Stem Cells; Thiophenes

2020
Isoxazole-9 reduces enhanced fear responses and retrieval in ethanol-dependent male rats.
    Journal of neuroscience research, 2021, Volume: 99, Issue:11

    Topics: Animals; Dentate Gyrus; Ethanol; Fear; Isoxazoles; Male; Rats; Rats, Wistar; Thiophenes

2021
ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude.
    Communications biology, 2022, 07-28, Volume: 5, Issue:1

    Topics: Aging; Animals; ARNTL Transcription Factors; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Circadian Rhythm; Homeostasis; Isoxazoles; Mice; Sleep; Thiophenes

2022