Compounds > thiophenes
Page last updated: 2024-08-18

thiophenes and n(6)-cyclopentyladenosine

thiophenes has been researched along with n(6)-cyclopentyladenosine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eglen, RM; Flippin, LA; Kim, EJ; Lazar, DA; Leung, E; Seran, CS; Walsh, LK; Wong, EH1
Bruns, RF; Montamat, SC; Mudumbi, RV; Vestal, RE1
Bhattacharya, S; Linden, J1
IJzerman, AP; Kourounakis, AP; van der Klein, PA1
de Ligt, RA; IJzerman, AP; Klaasse, E; Leurs, R; Lorenzen, A; Milligan, G; Roerink, SF1
de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA1
Halenda, SP; Shen, J; Sturek, M; Wilden, PA1
Beukers, MW; de Grip, WJ; Ijzerman, AP; Klaasse, EC; Roerink, SF; van den Hout, G1
Bhattacharya, S; Ghartey, K; Leonard, M; Linden, J; Tucker, AL; Youkey, RL1

Other Studies

9 other study(ies) available for thiophenes and n(6)-cyclopentyladenosine

ArticleYear
Enhancement of adenosine A1 receptor functions by benzoylthiophenes in guinea pig tissues in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Muscle Contraction; Myocardial Contraction; Peptides; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Purinergic P1; Ribonucleosides; Thienopyridines; Thiophenes; Wasp Venoms

1995
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2

    Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines

1993
Effects of long-term treatment with the allosteric enhancer, PD81,723, on Chinese hamster ovary cells expressing recombinant human A1 adenosine receptors.
    Molecular pharmacology, 1996, Volume: 50, Issue:1

    Topics: Adenosine; Allosteric Regulation; Animals; CHO Cells; Cricetinae; Cyclic AMP; Down-Regulation; Humans; Kinetics; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptors, Purinergic P1; Recombinant Proteins; Thiophenes; Transfection

1996
Allosteric modulation of the adenosine A(1) receptor. Synthesis and biological evaluation of novel 2-amino-3-benzoylthiophenes as allosteric enhancers of agonist binding.
    Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18

    Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; Brain; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Thiophenes; Xanthines

1999
Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Adenosine; Allosteric Site; Animals; Binding, Competitive; Cell Membrane; COS Cells; Cysteine; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutation; Radioligand Assay; Receptor, Adenosine A1; Recombinant Fusion Proteins; Sodium Chloride; Sulfur Radioisotopes; Thiophenes; Transfection; Tritium; Xanthines

2004
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines

2005
Novel mitogenic effect of adenosine on coronary artery smooth muscle cells: role for the A1 adenosine receptor.
    Circulation research, 2005, May-13, Volume: 96, Issue:9

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Amino Acid Sequence; Animals; Cell Proliferation; Cells, Cultured; Cloning, Molecular; Coronary Vessels; DNA; Mitogens; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Organ Culture Techniques; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptors, Purinergic P1; RNA, Messenger; Sus scrofa; Thiophenes

2005
Allosteric modulators affect the internalization of human adenosine A1 receptors.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Endocytosis; Humans; Luminescent Proteins; Microscopy, Confocal; Radioligand Assay; Receptor, Adenosine A1; Recombinant Fusion Proteins; Thiadiazoles; Thiazoles; Thiophenes; Transfection; Tritium; Xanthines

2005
The allosteric enhancer PD81,723 increases chimaeric A1/A2A adenosine receptor coupling with Gs.
    The Biochemical journal, 2006, May-15, Volume: 396, Issue:1

    Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Allosteric Regulation; Animals; Cell Line; Cyclic AMP; Dogs; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Iodobenzenes; Kidney; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Recombinant Fusion Proteins; Thiophenes; Transfection; Xanthines

2006