thiophenes has been researched along with methapyrilene in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kammerer, RC; Schmitz, DA | 1 |
| Graham, EE; Harding, JR; Hirst, CM; Kenna, JG; Maggs, JL; Martin, S; Park, BK; Peter, RM; Walsh, RJ; Wild, MJ; Williams, DP; Wilson, ID | 1 |
| Antoine, DJ; Benson, CA; Foster, J; Graham, EE; Hirst, CM; Kenna, JG; Mercer, AE; Park, BK; Regan, SL; Williams, DP | 1 |
3 other study(ies) available for thiophenes and methapyrilene
| Article | Year |
|---|---|
Metabolism of methapyrilene by rat-liver homogenate.
Topics: Aminopyridines; Animals; Gas Chromatography-Mass Spectrometry; Liver; Male; Methapyrilene; Rats; Rats, Inbred Strains; Thiophenes | 1986 |
Identification of the thiophene ring of methapyrilene as a novel bioactivation-dependent hepatic toxicophore.
Topics: Animals; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Glutathione; Hepatocytes; Histamine H1 Antagonists; Humans; Male; Methapyrilene; Mice; Mice, Inbred Strains; Microsomes, Liver; Molecular Structure; Rats; Rats, Wistar; Thiophenes | 2008 |
Functional and toxicological consequences of metabolic bioactivation of methapyrilene via thiophene S-oxidation: Induction of cell defence, apoptosis and hepatic necrosis.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Glutamate-Cysteine Ligase; Glutathione; Heme Oxygenase-1; Hepatocytes; Liver; Male; Methapyrilene; Necrosis; Oxidation-Reduction; Rats; Rats, Wistar; Thiophenes | 2009 |