thiophenes has been researched along with mdl 100907 in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dekeyne, A; Girardon, S; Millan, MJ | 1 |
| Cunningham, KA; Filip, M; McCreary, AC | 1 |
| Goto, F; Obata, H; Saito, S; Sakurazawa, S; Sasaki, M; Usui, T | 1 |
| Calama, E; Martín, ML; Morán, A; Ortiz de Urbina, AV; San Román, L | 1 |
| Günther, S; Maroteaux, L; Schwarzacher, SW | 1 |
| Bertaina-Anglade, V; Boyer, PA; la Rochelle, CD; Mocaër, E | 1 |
| Miyamoto, M; Terao, A | 1 |
| Asaka, M; Hattori, T; Katsurada, T; Nagai, K; Ohkawara, T; Sadakane, C; Takeda, H | 1 |
| Abdel-Aziz, AA; El-Aziz, NI; El-Bendary, ER; El-Kerdawy, MM; El-wasseef, DR | 1 |
| Al-Mousily, F; Byrne, BJ; Embury, J; Gannon, KS; Germain, S; Jacques, V; Murray, J; Porvasnik, SL; Shacham, S | 1 |
| MacFarlane, PM; Mitchell, GS; Vinit, S | 1 |
| Jolivalt, CG; Mixcoatl-Zecuatl, T | 1 |
| Al-Attas, OS; Arya, DS; Bharti, S; Chauhan, SS; Hussain, T; Singh, R | 1 |
| Fijał, K; Nikiforuk, A; Popik, P | 1 |
| Dong, YL; Hu, W; Li, HS; Lu, GJ; Sun, YH; Wu, SX; Yang, J; Zhao, GL; Zhu, C | 1 |
| Gwarek, M; Lübbert, H; Schmitz, B; Segelcke, D; Ullmer, C; Zhu, XR | 1 |
| Futamura, T; Hashimoto, K; Ishima, T; Kikuchi, T; Ohgi, Y; Yoshimi, N | 1 |
| Kimura, M; Mitsuhashi, M; Moteki, H; Naito, K; Natsume, H; Ogihara, M; Tanaka, C | 1 |
| Kimura, M; Moteki, H; Naito, K; Natsume, H; Ogihara, M | 1 |
| Stahl, SM | 1 |
| Bérubé, J; de la Fouchardière, A; Landreville, S; Piquet, L; Weidmann, C | 1 |
1 review(s) available for thiophenes and mdl 100907
| Article | Year |
|---|---|
[Recent and potential drugs for treatment of insomnia].
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Diphenhydramine; Drug Design; Fluorobenzenes; GABA-A Receptor Agonists; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Indenes; Orexin Receptors; Phenols; Piperazines; Pyridines; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Serotonin 5-HT2 Receptor Antagonists; Sleep Initiation and Maintenance Disorders; Thiophenes; Zolpidem | 2007 |
20 other study(ies) available for thiophenes and mdl 100907
| Article | Year |
|---|---|
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1999 |
Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Fenfluramine; Fluorobenzenes; Indoles; Ketanserin; Male; Piperidines; Pyrazines; Pyridines; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Thiophenes | 2003 |
Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury.
Topics: Amphetamines; Animals; Indoles; Injections, Spinal; Ketanserin; Ligation; Lumbar Vertebrae; Male; Neuralgia; Nociceptors; Piperazines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Nerves; Spiro Compounds; Sulfonamides; Thiophenes | 2004 |
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Indoles; Injections, Intra-Arterial; Injections, Intravenous; Male; Perfusion; Piperazines; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spiperone; Thiophenes; Vasoconstriction | 2004 |
Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro.
Topics: Animals; Animals, Newborn; In Vitro Techniques; Indoles; Ketanserin; Kinetics; Mice; Microinjections; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Respiration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2006 |
Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model.
Topics: Acetamides; Aminopyridines; Animals; Antidepressive Agents; Avoidance Learning; Helplessness, Learned; Imipramine; Indoles; Male; Melatonin; Rats; Rats, Wistar; Receptors, Melatonin; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2006 |
Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.
Topics: Acylation; Aminopyridines; Animals; Anorexia; Antineoplastic Agents; Body Weight; Chalcones; Cisplatin; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Eating; Flavones; Gastric Mucosa; Gastrointestinal Agents; Ghrelin; Hesperidin; Indoles; Male; Oligopeptides; Piperazines; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Ghrelin; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Stomach; Thiophenes; Vagotomy | 2008 |
Synthesis and pharmacological evaluation of novel fused thiophene derivatives as 5-HT2A receptor antagonists: molecular modeling study.
Topics: Animals; Cyclization; Drug Design; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Stereoisomerism; Structure-Activity Relationship; Thiophenes | 2010 |
PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats.
Topics: Animals; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Magnetic Resonance Imaging; Male; Monocrotaline; Myocardium; Organ Size; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2010 |
Serotonin 2A and 2B receptor-induced phrenic motor facilitation: differential requirement for spinal NADPH oxidase activity.
Topics: Acetophenones; Action Potentials; Amphetamines; Animals; Indoles; Injections, Spinal; Ketanserin; Male; NADPH Oxidases; Onium Compounds; Phrenic Nerve; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2011 |
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Hyperalgesia; Ketanserin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2011 |
Phosphorylation of Akt/GSK-3β/eNOS amplifies 5-HT2B receptor blockade mediated anti-hypertrophic effect in rats.
Topics: Animals; Cardiomegaly; Drug Evaluation, Preclinical; Drug Synergism; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Isoproterenol; Male; Maleimides; Myocardium; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Thiophenes | 2012 |
Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sulfonamides; Thiophenes | 2014 |
The analgesia effect of duloxetine on post-operative pain via intrathecal or intraperitoneal administration.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Idazoxan; Injections, Intraperitoneal; Injections, Spinal; Ketanserin; Male; Microdialysis; Norepinephrine; Pain, Postoperative; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spinal Cord; Thiophenes | 2014 |
BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs.
Topics: Animals; Blood Proteins; Brain; Cell Line; Guinea Pigs; Humans; Indoles; Male; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Substrate Specificity; Thiophenes; Thioxanthenes; Xanthenes | 2015 |
Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors.
Topics: Animals; Aripiprazole; Boron Compounds; Dose-Response Relationship, Drug; Drug Synergism; Fluorobenzenes; HSP90 Heat-Shock Proteins; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Nerve Growth Factor; Neurites; Oxazoles; PC12 Cells; Piperazines; Piperidines; Pyridines; Quinolones; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Agents; Thiophenes | 2015 |
Signal Transduction Mechanism for Serotonin 5-HT2B Receptor-Mediated DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes.
Topics: Animals; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hepatocytes; Indoles; Phosphorylation; Rats; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Thiophenes | 2016 |
Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-α in Primary Cultures of Adult Rat Hepatocytes.
Topics: Animals; Cell Proliferation; Cells, Cultured; DNA; Estrenes; Hepatocytes; Indoles; Male; Organic Chemicals; Pyrrolidinones; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes; Transforming Growth Factor alpha; Type C Phospholipases | 2016 |
Mechanism of action of brexpiprazole: comparison with aripiprazole.
Topics: Adrenergic alpha-1 Receptor Antagonists; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Dopamine Agonists; Humans; Quinolones; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Thiophenes | 2016 |
Expression of the serotonin receptor 2B in uveal melanoma and effects of an antagonist on cell lines.
Topics: Adult; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Female; Gene Expression Profiling; Histones; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Phosphorylation; Protein Kinases; Pyrimidines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; STAT5 Transcription Factor; Thiophenes; Uveal Neoplasms | 2018 |