thiophenes has been researched along with hydrazine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.63) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 12 (37.50) | 24.3611 |
| 2020's | 7 (21.88) | 2.80 |
| Authors | Studies |
|---|---|
| Aber, VR; Allen, BW; Goren, MB; Grange, JM; Mitchison, DA | 1 |
| Collins, CH; Yates, MD | 1 |
| Dybing, E; McMurtry, RJ; Mitchell, JR; Nelson, SD; Thorgeirsson, SS | 1 |
| Calleja, JM; Dominguez, NG; Gil-Longo, J; Masaguer, CF; Orallo, F; Ravina, E; Teran, C | 1 |
| Jackson, M; Jenner, P; Treseder, SA | 1 |
| Doss, SH; Louca, NA; Wardakhan, WW | 1 |
| FEDI, M | 1 |
| ASAGI, S; KAMETANI, T; UMEZAWA, O; YAGI, H | 1 |
| Crooks, PA; Parkin, S; Sonar, VN | 1 |
| Dobosz, M; Kosikowska, U; Malm, A; Pitucha, M; Wujec, M | 1 |
| Case, A; Cuny, GD; Duval, E; Stein, RL | 1 |
| Brzezinski, B; Lewandowska, W; Przybylski, P; Schilf, W | 1 |
| Nurden, AT; Nurden, P; Viallard, JF | 1 |
| Abe, M; Hirayama, F; Itoh, H; Kawasaki, T; Koga, Y; Naganuma, S; Sakata, C; Sugasawa, K; Suzuki, K | 1 |
| Abu-Hashem, AA; Badria, FA; El-Shehry, MF | 1 |
| Al-Omran, F; Mohareb, RM | 1 |
| Basciano, PA; Bussel, J; Christos, PJ; Giannakakou, P; Hafeez, Z | 1 |
| Antunes, F; Barreiro, EJ; Fraga, CA; Kummerle, AE; Silva, GA; Sudo, RT; Zapata-Sudo, G | 1 |
| Balachandran, V; Janaki, A; Nataraj, A | 1 |
| Mishra, M; Mishra, R; Shukla, S; Singh, VP; Tiwari, K | 1 |
| de Knegt, RJ; Maan, R; Veldt, BJ | 1 |
| Abdelaziz, MA; El-Sayed, NN; Mohareb, RM; Wardakhan, WW | 1 |
| Afsharinasab, A; Almasirad, A; Amanzadeh, A; Dehghani, S; Kooshafar, Z; Mousavi, E; Salimi, M; Shafiee, S; Tavakolfar, S | 1 |
| Al-Samkari, H; Kuter, DJ | 1 |
| Abbas, NS; Mohareb, RM; Wardakhan, WW | 1 |
| Qing, Z; Wang, T; Zhai, H; Zhao, H | 1 |
| Chen, J; Guo, Z; Li, T; Niu, Q; Qin, X; Wei, T; Yang, L; Yang, Q | 1 |
| Bussel, JB; Lee, EJ; Seshadri, M | 1 |
| Bubalo, J; Gilreath, J; Lo, M | 1 |
| Fang, L; Jiang, CS; Li, Y; Song, Z; Wang, KM; Xie, HX; Zhang, J; Zhang, JH; Zhu, KK | 1 |
| Arif, AR; Chen, W; Luo, S; Wang, Y; Xue, M; Zhao, M | 1 |
| Borodina, TN; Korchevin, NA; Manuilov, VV; Nikonova, VS; Rozentsveig, IB; Smirnov, VI; Ushakov, IA | 1 |
4 review(s) available for thiophenes and hydrazine
| Article | Year |
|---|---|
Metabolic activation: biochemical basis for many drug-induced liver injuries.
Topics: Acetaminophen; Animals; Binding Sites; Carcinogens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Hydrazines; Isoniazid; Liver; Methyldopa; Necrosis; Pharmaceutical Preparations; Phenacetin; Thiophenes | 1976 |
New-generation drugs that stimulate platelet production in chronic immune thrombocytopenic purpura.
Topics: Benzoates; Carrier Proteins; Chronic Disease; Drug Approval; Hemorrhage; Humans; Hydrazines; Megakaryocytes; Methacrylates; Patient Selection; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Safety; Thiazoles; Thiophenes; Thrombopoiesis; Thrombopoietin; Treatment Outcome; United States; United States Food and Drug Administration | 2009 |
Management of Thrombocytopenia in Chronic Liver Disease: Focus on Pharmacotherapeutic Strategies.
Topics: Benzoates; Chronic Disease; Disease Management; Hepatitis C, Chronic; Humans; Hydrazines; Liver Diseases; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin | 2015 |
Thrombopoietin Receptor Agonists (TPO-RAs): Drug Class Considerations for Pharmacists.
Topics: Benzoates; Cinnamates; Dose-Response Relationship, Drug; Drug Monitoring; Health Knowledge, Attitudes, Practice; Humans; Hydrazines; Pharmacists; Platelet Count; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin | 2021 |
28 other study(ies) available for thiophenes and hydrazine
| Article | Year |
|---|---|
The correlation of bacteriophage types of Mycobacterium tuberculosis with guinea-pig virulence and in vitro-indicators of virulence.
Topics: Aminosalicylic Acid; Animals; Bacteriophage Typing; Guinea Pigs; Hydrazines; Hydrogen Peroxide; Lipids; Mycobacteriophages; Mycobacterium tuberculosis; Thioacetazone; Thiophenes | 1978 |
Identification of tubercle bacilli.
Topics: Bacteriological Techniques; Bacteriophage Typing; Ethnicity; Furans; Humans; Hydrazines; Microbial Sensitivity Tests; Mycobacterium; Pyrazinamide; Thiophenes | 1979 |
Pyridazine derivatives, VIII: Synthesis and antihypertensive activity of 6-(2-thienyl)-5-aminomethyl-3-hydrazino-pyridazines.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Female; Hemodynamics; Hydrazines; In Vitro Techniques; Muscle, Smooth, Vascular; Pyridazines; Rats; Rats, Inbred Strains; Thiophenes | 1991 |
The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine | 2000 |
The reaction of digitoxin and digoxin with cyanoacetic acid hydrazide: synthesis of coumarin, thiazole, thiophene and pyridine derivatives with potential biological activities.
Topics: Coumarins; Digitoxin; Digoxin; Hydrazines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Pyridines; Thiazoles; Thiophenes | 2001 |
[Condensations of isonicotinic and cyanacetic hydrazides with some thienyl ketones. III].
Topics: Anti-Bacterial Agents; Hydrazines; Isoniazid; Ketones; Thiophenes | 1961 |
[A NOVEL DEHYDRAZINATION REACTION. IV. THE REACTION OF HETEROCYCLIC CARBOXYLIC ACID HYDRAZIDES WITH CHLORAL].
Topics: Anti-Bacterial Agents; Carboxylic Acids; Chemical Phenomena; Chemistry; Chloral Hydrate; Furans; Hydrazines; Pyridines; Research; Thiophenes | 1965 |
(E)-N-[(Benzo[b]thiophen-3-yl)methylene]-N'-(2,5-dichlorophenyl)hydrazine.
Topics: Antitubercular Agents; Crystallography, X-Ray; Hydrazines; Hydrogen Bonding; Molecular Structure; Mycobacterium tuberculosis; Thiophenes | 2004 |
Synthesis and potential antimycotic activity of 4-substituted-3-(thiophene-2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones.
Topics: Antifungal Agents; Chemistry, Pharmaceutical; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Semicarbazides; Technology, Pharmaceutical; Thiones; Thiophenes; Triazoles | 2004 |
Structure-activity relationship study of novel tissue transglutaminase inhibitors.
Topics: Binding Sites; Caseins; Catalysis; Cells, Cultured; Enzyme Inhibitors; Hydrazines; Inhibitory Concentration 50; Peptides; Structure-Activity Relationship; Substrate Specificity; Sulfides; Thiophenes; Transglutaminases | 2005 |
Multinuclear magnetic resonance, electrospray ionization-mass spectroscopy, and parametric method 5 studies of a new derivative of gossypol with 2-thiophenecarbohydrazide as well as its complexes with LI+, Na+, K+, RB+, and Cs+ cations.
Topics: Cations, Monovalent; Cesium; Dimethyl Sulfoxide; Gossypol; Hydrazines; Isomerism; Lithium; Magnetic Resonance Spectroscopy; Metals; Molecular Structure; Potassium; Sodium; Spectrometry, Mass, Electrospray Ionization; Thiophenes | 2006 |
Pharmacological profile of AS1670542, a novel orally-active human thrombopoietin receptor agonist.
Topics: Administration, Oral; Amino Acid Sequence; Animals; Antigens, CD34; Benzoates; Cell Line; Cell Membrane; Dogs; Female; Histidine; Humans; Hydrazines; Liver; Mice; Molecular Sequence Data; Platelet Count; Protein Structure, Tertiary; Pyrazoles; Rats; Receptors, Thrombopoietin; Species Specificity; Stem Cell Transplantation; Thiazoles; Thiophenes | 2011 |
Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents.
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Ehrlich Tumor; Drug Design; Hydrazines; Mice; Pyrazoles; Pyrimidines; Rats; Thiophenes | 2010 |
Reaction of pregnenolone with cyanoacetylhydrazine: novel synthesis of hydrazide-hydrazone, pyrazole, pyridine, thiazole, thiophene derivatives and their cytotoxicity evaluations.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Hydrazines; Hydrazones; Nitriles; Pregnenolone; Pyrazoles; Pyridines; Thiazoles; Thiophenes | 2012 |
The beta 1 tubulin R307H single nucleotide polymorphism is associated with treatment failures in immune thrombocytopenia (ITP).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Antibodies, Monoclonal, Murine-Derived; Benzoates; Biomarkers; Child; Child, Preschool; Female; Gene Frequency; Genotype; Humans; Hydrazines; Immunologic Factors; Infant; Male; Middle Aged; Phenotype; Platelet Count; Polymorphism, Single Nucleotide; Purpura, Thrombocytopenic, Idiopathic; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Retrospective Studies; Rituximab; Thiazoles; Thiophenes; Thrombopoiesis; Thrombopoietin; Treatment Failure; Tubulin | 2013 |
Impairment of locomotor activity induced by the novel N-acylhydrazone derivatives LASSBio-785 and LASSBio-786 in mice.
Topics: Animals; Hydrazines; Hydrazones; Hypnotics and Sedatives; Male; Mice; Motor Activity; Receptors, GABA; Thiophenes | 2013 |
Theoretical investigations on molecular structure, vibrational spectra, HOMO, LUMO, NBO analysis and hyperpolarizability calculations of thiophene-2-carbohydrazide.
Topics: Electrons; Hydrazines; Models, Molecular; Molecular Conformation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Thermodynamics; Thiophenes; Vibration | 2014 |
Synthesis, structural investigation, DNA and protein binding study of some 3d-metal complexes with N'-(phenyl-pyridin-2-yl-methylene)-thiophene-2-carboxylic acid hydrazide.
Topics: Animals; Binding, Competitive; Carbon-13 Magnetic Resonance Spectroscopy; Cattle; Coordination Complexes; Crystallography, X-Ray; DNA; DNA Cleavage; Electrons; Ethidium; Hydrazines; Hydrogen Bonding; Ligands; Magnetic Phenomena; Molecular Conformation; Protein Binding; Proton Magnetic Resonance Spectroscopy; Pyridines; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiophenes | 2014 |
The Knoevenagel reaction of cyanoacetylhydrazine with pregnenolone: Synthesis of thiophene, thieno[2,3-d]pyrimidine, 1,2,4-triazole, pyran and pyridine derivatives with anti-inflammatory and anti-ulcer activities.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Hydrazines; Pandalidae; Pregnenolone; Thiophenes; Triazoles | 2016 |
In vitro and in vivo assessments of two novel hydrazide compounds against breast cancer as well as mammary tumor cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Female; Furans; G1 Phase; Humans; Hydrazines; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice, Inbred BALB C; Proto-Oncogene Proteins c-bcl-2; Thiophenes | 2017 |
Relative potency of the thrombopoietin receptor agonists eltrombopag, avatrombopag and romiplostim in a patient with chronic immune thrombocytopenia.
Topics: Benzoates; Dose-Response Relationship, Drug; Female; Hematologic Agents; Humans; Hydrazines; Middle Aged; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombopoietin; Treatment Outcome | 2018 |
Synthesis of Tetrahydrobenzo[
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Structure-Activity Relationship; Thiophenes | 2019 |
Cobalt-catalyzed 2-(1-methylhydrazinyl)pyridine-assisted cyclization of thiophene-2-carbohydrazides with maleimides: efficient synthesis of thiophene-fused pyridones.
Topics: Catalysis; Cobalt; Cyclization; Hydrazines; Maleimides; Molecular Structure; Pyridines; Pyridones; Stereoisomerism; Thiophenes | 2020 |
New "naked-eye" colori/fluorimetric "turn-on" chemosensor: Ultrafast and ultrasensitive detection of hydrazine in ∼100% aqueous solution and its bio-imaging in living cells.
Topics: Colorimetry; Fluorescent Dyes; Fluorometry; HeLa Cells; Humans; Hydrazines; Molecular Structure; Optical Imaging; Quantum Theory; Solutions; Thiophenes; Water | 2020 |
Clinical outcomes in eight patients with immune thrombocytopenia each treated with the three approved thrombopoietin receptor agonists.
Topics: Adult; Aged; Benzoates; Female; Humans; Hydrazines; Male; Middle Aged; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin; Treatment Outcome | 2021 |
Design, synthesis and biological evaluation of novel (E)-2-benzylidene-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)hydrazine-1-carboxamide derivatives as α-glucosidase inhibitors.
Topics: alpha-Glucosidases; Animals; Blood Glucose; Cell Line; Dose-Response Relationship, Drug; Drug Design; Glycoside Hydrolase Inhibitors; Humans; Hydrazines; Hypoglycemic Agents; Molecular Structure; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sucrose; Thiophenes | 2021 |
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure.
Topics: Benzoates; Hearing Loss, Sensorineural; Humans; Hydrazines; Male; Molecular Motor Proteins; Mutation; Myosin Heavy Chains; Pyrazoles; Thiazoles; Thiophenes; Thrombocytopenia; Treatment Failure | 2022 |
Heterocyclization of Bis(2-chloroprop-2-en-1-yl)sulfide in Hydrazine Hydrate-KOH: Synthesis of Thiophene and Pyrrole Derivatives.
Topics: Alkalies; Hydrazones; Pyrroles; Sulfides; Sulfur; Thiophenes | 2022 |