thiophenes has been researched along with gw0742 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 15 (88.24) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Billin, AN; Grillot, DA; Iannone, MA; Lazar, MA; Lobe, DC; Shearer, BG; Stanley, TB; Steger, DJ; Way, JM; Willson, TM | 1 |
| Duarte, J; Galindo, P; Gómez-Guzmán, M; Haro, JM; Jiménez, R; López-Sepúlveda, R; Pérez-Vizcaíno, F; Quintela, AM; Romero, M; Sánchez, M; Zarzuelo, A; Zarzuelo, MJ | 1 |
| Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Galuppo, M; Kapoor, A; Mazzon, E; Paterniti, I; Thiemermann, C | 1 |
| Bahrami, S; Bishop-Bailey, D; Busch, D; Castiglia, S; Collino, M; Desvergne, B; Fantozzi, R; Kapoor, A; Mitchell, JA; Mota-Filipe, H; Osuchowski, MF; Patel, NS; Sepodes, B; Shintani, Y; Suzuki, K; Thiemermann, C; Yaqoob, MM | 1 |
| Evans, RM; Martin, HL; Mounsey, RB; Mustafa, S; Nelson, MC; Sathe, K; Teismann, P | 1 |
| Capozzi, ME; McCollum, GW; Penn, JS; Savage, SR | 1 |
| Bao, XC; Fang, YQ; Ma, J; You, P; Zhang, S | 2 |
| Galatou, E; Kelly, T; Lazou, A | 1 |
| Cogolludo, Á; Duarte, J; Gálvez, J; Gómez-Guzmán, M; Hermenegildo, C; Jiménez, R; Pérez-Vizcaíno, F; Romero, M; Toral, M; Utrilla, MP; Zarzuelo, MJ | 1 |
| Barroso, E; Briones, AM; Cogolludo, Á; Duarte, J; García-Redondo, AB; Gómez-Guzmán, M; Jiménez, R; Mahmoud, AM; Pérez-Vizcaíno, F; Romero, M; Sánchez, M; Toral, M; Vázquez-Carrera, M | 1 |
| Duarte, J; Jiménez, R; Martínez, MC; Pérez-Vizcaíno, F; Robles-Vera, I; Romero, M; Tamargo, J; Toral, M | 1 |
| Dessy, C; Duarte, J; Gómez-Gúzman, M; Jiménez, R; León-Gómez, E; Pérez-Vizcaíno, F; Rath, G; Rodríguez-Gómez, I; Romero, M; Sánchez, M; Tamargo, J; Toral, M; Zarzuelo, MJ | 1 |
| Agarwal, AK; Garg, A; Sankella, S | 1 |
| Bahrami, S; Busch, D; Hildebrand, F; Kapoor, A; Osuchowski, MF; Rademann, P; Thiemermann, C | 1 |
| Chang, WT; Chen, ZC; Cheng, JT; Cheng, KC; Cheng, YZ; Li, Y | 1 |
| Berga, SL; Man, M; Rajakumar, A; Sidell, N; Taylor, RN; Yu, J; Zou, W | 1 |
17 other study(ies) available for thiophenes and gw0742
| Article | Year |
|---|---|
Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist.
Topics: Cells, Cultured; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Fatty Acids; Fluorescence Resonance Energy Transfer; Gene Expression Regulation; Humans; Ligands; Molecular Structure; Muscle, Skeletal; Oxidation-Reduction; PPAR delta; PPAR-beta; Sulfones; Thiazoles; Thiophenes | 2008 |
Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway.
Topics: Anilides; Animals; Aorta; Chromones; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; Morpholines; Nitric Oxide; Nitric Oxide Synthase Type III; Phenoxyacetates; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; PPAR-beta; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Sulfones; Thiazoles; Thiophenes; Umbilical Veins; Vasodilation | 2010 |
Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury.
Topics: Animals; Apoptosis; Cytokines; Enzyme Induction; Fas Ligand Protein; Male; Mice; Neutrophil Infiltration; Nitric Oxide Synthase; Peroxidase; PPAR delta; PPAR-beta; Spinal Cord Injuries; Sulfones; Thiazoles; Thiophenes; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock.
Topics: Animals; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; PPAR delta; PPAR-beta; Proto-Oncogene Proteins c-akt; Shock, Septic; Signal Transduction; Sulfones; Thiazoles; Thiophenes | 2010 |
A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Count; Cells, Cultured; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Female; Glial Fibrillary Acidic Protein; Humans; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Parkinsonian Disorders; PPAR delta; Rats; Sulfones; Thiazoles; Thiophenes; Tyrosine 3-Monooxygenase | 2013 |
Peroxisome proliferator-activated receptor-β/δ regulates angiogenic cell behaviors and oxygen-induced retinopathy.
Topics: Angiogenesis Inhibitors; Animals; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Humans; Oxygen; PPAR delta; PPAR-beta; Rats; Retinal Diseases; Retinal Neovascularization; Retinal Vessels; Sulfones; Thiazoles; Thiophenes | 2013 |
Protective role of peroxisome proliferator-activated receptor-β/δ against pulmonary oxygen toxicity mediated through changes in NOS expression levels.
Topics: Acute Lung Injury; Animals; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Oxygen; PPAR delta; PPAR-beta; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfones; Thiazoles; Thiophenes; Up-Regulation | 2014 |
Protective role of peroxisome proliferator-activated receptor β/δ in acute lung injury induced by prolonged hyperbaric hyperoxia in rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Apoptosis; Cytokines; Disease Models, Animal; Hyperoxia; Lung; Male; MAP Kinase Signaling System; Neuroprotective Agents; NF-kappa B; PPAR delta; PPAR-beta; Pressure; Random Allocation; Rats, Sprague-Dawley; Respiratory System Agents; Sulfones; Thiazoles; Thiophenes; Time Factors | 2014 |
The PPARβ/δ agonist GW0742 modulates signaling pathways associated with cardiac myocyte growth via a non-genomic redox mechanism.
Topics: Animals; Gene Expression Regulation; Male; MAP Kinase Signaling System; Myocytes, Cardiac; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; PTEN Phosphohydrolase; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfones; Thiazoles; Thiophenes; Vanadates | 2014 |
Chronic peroxisome proliferator-activated receptorβ/δ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity.
Topics: Adiponectin; Adipose Tissue; Animals; Aorta; Blood Glucose; Caveolin 1; Diet, High-Fat; Endothelium, Vascular; Glucose Tolerance Test; Hypertension; Insulin Resistance; Interleukin-6; Male; Mice; Nitric Oxide Synthase Type III; Obesity; PPAR delta; PPAR-beta; Reactive Oxygen Species; Sulfones; Thiazoles; Thiophenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vasodilation | 2015 |
Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.
Topics: Animals; Aorta; Blotting, Western; Calcimycin; Carnitine O-Palmitoyltransferase; Cells, Cultured; Diglycerides; Endothelium, Vascular; Enzyme Activation; Lipids; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Palmitic Acids; Phosphorylation; PPAR delta; PPAR-beta; Protein Kinase C-alpha; Reactive Oxygen Species; RNA Interference; Sulfones; Thiazoles; Thiophenes; Up-Regulation | 2015 |
Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction.
Topics: Animals; Aorta; Calcimycin; Cytochrome b Group; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; PPAR gamma; PPAR-beta; Primary Cell Culture; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Sulfones; Thiazoles; Thiophenes; Tissue Culture Techniques; Uncoupling Protein 2 | 2016 |
Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Mesenteric Arteries; Mice, Inbred C57BL; Norepinephrine; PPAR-beta; RGS Proteins; Sulfones; Thiazoles; Thiophenes; Vascular Resistance; Vasoconstriction | 2016 |
Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.
Topics: Acyltransferases; Anilides; Animals; Blotting, Northern; Caco-2 Cells; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Computational Biology; HT29 Cells; Humans; Kidney Tubules, Proximal; Liver; Mice; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sulfones; Thiazoles; Thiazolidinediones; Thiophenes; Tyrosine | 2016 |
Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation.
Topics: Animals; Blood Coagulation; Cytokines; Female; Inflammation; Mice; PPAR delta; PPAR-beta; Sepsis; Sulfones; Thiazoles; Thiophenes | 2018 |
GW0742 activates peroxisome proliferator-activated receptor δ to reduce free radicals and alleviate cardiac hypertrophy induced by hyperglycemia in cultured H9c2 cells.
Topics: Animals; Blotting, Western; Calcium; Cardiomegaly; Cell Line; Free Radicals; Hyperglycemia; Rats; Reactive Oxygen Species; Sulfones; Thiazoles; Thiophenes | 2018 |
Human Endometrial Stromal Cell Differentiation is Stimulated by PPARβ/δ Activation: New Targets for Infertility?
Topics: Adult; Cell Differentiation; Cells, Cultured; Decidua; Endometrium; Female; Humans; Infertility, Female; Ligands; Molecular Targeted Therapy; PPAR delta; PPAR-beta; Stromal Cells; Sulfones; Thiazoles; Thiophenes; Up-Regulation | 2020 |