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thiophenes and guanosine 5'-o-(3-thiotriphosphate)

thiophenes has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's4 (40.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daly, JW; Moni, RW; Romero, FS1
Belardinelli, L; Harrison, JK; Jacobson, M; Kollias-Baker, CA; Ozeck, M; Ruble, J; Shryock, JC1
Maekawa, M; Miyazaki, H; Murayama, T; Narita, H; Nomura, Y; Ono, S1
de Ligt, RA; IJzerman, AP; Klaasse, E; Leurs, R; Lorenzen, A; Milligan, G; Roerink, SF1
de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA1
Gonzalez-Cabrera, PJ; Hla, T; Rosen, H1
Goforth, PB; Lynch, KR; Macdonald, TL; Mba, MU; Milstien, S; Satin, LS; Selley, DE; Sim-Selley, LJ; Spiegel, S; Welch, SP1
Christopoulos, A; Felder, CC; Leach, K; Loiacono, RE; McKinzie, DL; Mogg, A; Sexton, PM; Shaw, DB1
Brogi, S; Carai, MA; Castelli, MP; Casti, P; Casu, A; Colombo, G; Corelli, F; Gessa, GL; Giunta, D; Lobina, C; Mugnaini, C; Pasquini, S; Solinas, M; Tafi, A1
Castelli, MP; Casti, A; Casu, A; Colombo, G; Corelli, F; Dragoni, S; Gessa, GL; Giunta, D; Lamponi, S; Lobina, C; Maccioni, P; Mugnaini, C; Pedani, V; Porcu, A; Solinas, M; Valoti, M1

Other Studies

10 other study(ies) available for thiophenes and guanosine 5'-o-(3-thiotriphosphate)

ArticleYear
The amphiphilic peptide adenoregulin enhances agonist binding to A1-adenosine receptors and [35S]GTP gamma S to brain membranes.
    Cellular and molecular neurobiology, 1995, Volume: 15, Issue:4

    Topics: Adenosine; Adrenergic alpha-Agonists; Amphibian Proteins; Animals; Antimicrobial Cationic Peptides; Brain; Cell Line; Cell Membrane; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Magnesium Chloride; Peptides; Purinergic P1 Receptor Agonists; Ranidae; Rats; Receptors, Purinergic P1; Sodium Chloride; Sulfur Radioisotopes; Thiophenes; Tritium; Xanthines

1995
Agonist-independent effect of an allosteric enhancer of the A1 adenosine receptor in CHO cells stably expressing the recombinant human A1 receptor.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Allosteric Regulation; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recombinant Proteins; Thiophenes; Xanthines

1997
Effects of T-588, a novel cognitive enhancer, on ADP-ribosylation of G(s alpha) by cholera toxin and cyclic AMP accumulation in rat cerebral cortex.
    Neurochemistry international, 1999, Volume: 34, Issue:2

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding Sites; Catalysis; Cerebral Cortex; Cholera Toxin; Cyclic AMP; Diethylamines; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Nootropic Agents; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Thiophenes; Virulence Factors, Bordetella

1999
Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Adenosine; Allosteric Site; Animals; Binding, Competitive; Cell Membrane; COS Cells; Cysteine; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutation; Radioligand Assay; Receptor, Adenosine A1; Recombinant Fusion Proteins; Sodium Chloride; Sulfur Radioisotopes; Thiophenes; Transfection; Tritium; Xanthines

2004
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines

2005
Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.
    The Journal of biological chemistry, 2007, Mar-09, Volume: 282, Issue:10

    Topics: Cells, Cultured; Chloroquine; Fingolimod Hydrochloride; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Lysophospholipids; Oxadiazoles; Propylene Glycols; Protein Transport; Proteomics; Receptors, G-Protein-Coupled; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Ubiquitin

2007
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.
    Journal of neurochemistry, 2009, Volume: 110, Issue:4

    Topics: Animals; Animals, Newborn; Binding, Competitive; Cannabinoids; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Lysophospholipids; Neurons; Oxadiazoles; Patch-Clamp Techniques; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Lysosphingolipid; Receptors, Neurotransmitter; Signal Transduction; Sphingosine; Sulfur Radioisotopes; Synaptic Transmission; Thiophenes

2009
Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:4

    Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Cell Line; Corpus Striatum; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Mice; Mice, Knockout; Models, Molecular; Multivariate Analysis; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Acids; Parasympatholytics; Phosphorylation; Protein Transport; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptor, Muscarinic M4; Signal Transduction; Thiophenes; Tritium

2010
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:3

    Topics: Adamantane; Allosteric Regulation; Animals; Baclofen; Binding Sites; GABA Modulators; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred DBA; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Thiophenes

2012
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor.
    Journal of medicinal chemistry, 2013, May-09, Volume: 56, Issue:9

    Topics: Administration, Oral; Allosteric Regulation; Animals; Baclofen; Chemistry Techniques, Synthetic; Drug Design; Drug Stability; Guanosine 5'-O-(3-Thiotriphosphate); Immobility Response, Tonic; Mice; Microsomes, Liver; NIH 3T3 Cells; Pentobarbital; Rats; Receptors, GABA-B; Thiophenes

2013