Compounds > thiophenes
Page last updated: 2024-08-18

thiophenes and gne-317

thiophenes has been researched along with gne-317 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alicke, B; Barck, K; Carano, RA; Cheong, J; Edgar, KA; Gould, SE; Greve, J; Heffron, TP; Kharbanda, S; Koeppen, H; Lau, S; Lee, LB; Nishimura, M; Olivero, AG; Pang, J; Phillips, HS; Plise, EG; Pokorny, JL; Reslan, HB; Salphati, L; Sarkaria, JN; Wallin, JJ; Zhang, X1
Alicke, B; Barck, K; Carano, RA; Nishimura, M; Olivero, AG; Pang, J; Phillips, HS; Quiason, C; Salphati, L; Shahidi-Latham, S1
Becker, CM; Brinkmann, DH; Elmquist, WF; Largaespada, DA; McFarren, SJ; Muldoon, DM; Oberoi, RK; Ohlfest, JR; Pafundi, DH; Pokorny, JL; Sarkaria, JN1
Kharbanda, S; Lacap, JA; Lewis Phillips, GD; Mai, E; Malesky, K; Marik, J; Nishimura, MC; Phillips, HS; Tien, J; Williams, SP1

Other Studies

4 other study(ies) available for thiophenes and gne-317

ArticleYear
Targeting the PI3K pathway in the brain--efficacy of a PI3K inhibitor optimized to cross the blood-brain barrier.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Nov-15, Volume: 18, Issue:22

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cell Line; Cell Membrane Permeability; Dogs; Female; Glioblastoma; Humans; Mice; Molecular Targeted Therapy; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Thiophenes; Tumor Burden; Xenograft Model Antitumor Assays

2012
Distribution of the phosphatidylinositol 3-kinase inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 intracranial glioblastoma models-assessment by matrix-assisted laser desorption ionization imaging.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:7

    Topics: Animals; Brain Neoplasms; Enzyme Inhibitors; Female; Glioblastoma; Humans; Indazoles; Mice; Mice, Nude; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfonamides; Thiophenes; Tissue Distribution

2014
Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Brain Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Drug Delivery Systems; Glioblastoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Thiophenes; TOR Serine-Threonine Kinases

2015
Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis.
    Breast cancer research and treatment, 2017, Volume: 164, Issue:3

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Female; Humans; Mice; Mice, Transgenic; Pyrimidines; Receptor, ErbB-2; Survival Analysis; Thiophenes; Tissue Distribution; Trastuzumab; Treatment Outcome; Xenograft Model Antitumor Assays

2017