Page last updated: 2024-08-18

thiophenes and gdc 0449

thiophenes has been researched along with gdc 0449 in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bee, WL; Copeland, RA; Davenport, EA; Gilmartin, A; Gontarek, R; Hornberger, KR; Kallal, LA; Lai, Z; Lawrie, K; Lu, Q; McMillan, L; Rominger, CM; Rominger, DH; Truong, M; Tummino, PJ; Turunen, B; Will, M; Zuercher, WJ	1
Peng, LF; Stanton, BZ	1
Bohinc, B; Diehl, AM; Michelotti, G	1

Reviews

1 review(s) available for thiophenes and gdc 0449

Article	Year
Small-molecule modulators of the Sonic Hedgehog signaling pathway. Molecular bioSystems, 2010, Volume: 6, Issue:1 Topics: Anilides; Animals; Dioxoles; Hedgehog Proteins; Humans; Models, Biological; Molecular Structure; Piperazines; Pyrazoles; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor; Thiophenes; Veratrum Alkaloids	2010

Other Studies

2 other study(ies) available for thiophenes and gdc 0449

Article	Year
Evidence for allosteric interactions of antagonist binding to the smoothened receptor. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Anilides; Animals; Benzamides; Benzimidazoles; beta-Lactamases; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Cyclohexylamines; Genes, Reporter; Humans; Kinetics; Mice; Molecular Structure; Morpholines; NIH 3T3 Cells; Piperazines; Purines; Pyrazoles; Pyridines; Radioligand Assay; Receptors, G-Protein-Coupled; Recombinant Proteins; Smoothened Receptor; Thiophenes; Tomatine; Transfection; Veratrum Alkaloids	2009
Hedgehog signaling in human medullary thyroid carcinoma: a novel signaling pathway. Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:9 Topics: Anilides; Apoptosis; Biomarkers, Tumor; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Cyclohexylamines; Hedgehog Proteins; Humans; Kruppel-Like Transcription Factors; Nuclear Proteins; Pyridines; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Smoothened Receptor; Thiophenes; Thyroid Neoplasms; Time Factors; Up-Regulation; Zinc Finger Protein Gli2	2013

Article

Year

Evidence for allosteric interactions of antagonist binding to the smoothened receptor.

The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

Topics: Anilides; Animals; Benzamides; Benzimidazoles; beta-Lactamases; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Cyclohexylamines; Genes, Reporter; Humans; Kinetics; Mice; Molecular Structure; Morpholines; NIH 3T3 Cells; Piperazines; Purines; Pyrazoles; Pyridines; Radioligand Assay; Receptors, G-Protein-Coupled; Recombinant Proteins; Smoothened Receptor; Thiophenes; Tomatine; Transfection; Veratrum Alkaloids

2009

Hedgehog signaling in human medullary thyroid carcinoma: a novel signaling pathway.

Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:9

Topics: Anilides; Apoptosis; Biomarkers, Tumor; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Cyclohexylamines; Hedgehog Proteins; Humans; Kruppel-Like Transcription Factors; Nuclear Proteins; Pyridines; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Smoothened Receptor; Thiophenes; Thyroid Neoplasms; Time Factors; Up-Regulation; Zinc Finger Protein Gli2

2013