Page last updated: 2024-08-18

thiophenes and gant58

thiophenes has been researched along with gant58 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (63.64)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
Peng, LF; Stanton, BZ1
Chen, X; Fan, Y; Hao, W; Hou, X; Jin, Y; Liu, F; Ma, A; Pang, T; Song, Z; Wang, W; Wang, Y; Zhang, P1
Cheng, K; Lan, X; Malhotra, A; Marashi Shoshtari, SS; Plagov, A; Singhal, PC; Wen, H1
Chang, CF; Jeng, CJ; Jeng, KS; Lu, SJ; Sheen, IS; Wang, CH; Wu, SH1
Cao, H; Chen, L; Chen, X; Han, X; Hou, J; Hu, K; Shi, C; Xiang, Z1
Cho, SY; Kim, D; Kim, YO; Kwon, J; Oh, MJ; Protzman, RA; Vaidya, B1
Duvall, CL; Guelcher, SA; Gupta, MK; Johnson, RW; Kwakwa, KA; Merkel, AR; Rhoades, JA; Vanderburgh, JP; Werfel, TA1
Bedingfield, SK; d'Arcy, R; Duvall, CL; Guelcher, SA; Gupta, MK; Hill, JL; Kwakwa, KA; Merkel, AR; Moyer, K; Rhoades, JA; Vanderburgh, J; Wang, SK1
Haraguchi, R; Imai, Y; Kitazawa, R; Kitazawa, S; Kohara, Y1
Dadwal, UC; Kessler, M; Kwakwa, KA; Merkel, AR; Page, JM; Rhoades, JA1
Bhattacharyya, S; De, R; Kaur, H; Pal, A; Sharma, A; Srinivasan, R1

Reviews

1 review(s) available for thiophenes and gant58

ArticleYear
Small-molecule modulators of the Sonic Hedgehog signaling pathway.
    Molecular bioSystems, 2010, Volume: 6, Issue:1

    Topics: Anilides; Animals; Dioxoles; Hedgehog Proteins; Humans; Models, Biological; Molecular Structure; Piperazines; Pyrazoles; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor; Thiophenes; Veratrum Alkaloids

2010

Other Studies

10 other study(ies) available for thiophenes and gant58

ArticleYear
Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells.
    Biochimie, 2014, Volume: 101

    Topics: Antineoplastic Agents; Apoptosis; Drug Screening Assays, Antitumor; Drug Synergism; Hedgehog Proteins; Humans; Jurkat Cells; MAP Kinase Signaling System; Oxadiazoles; Phosphorylcholine; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; Pyridines; Thiophenes; Transcription Factors; Veratrum Alkaloids; Zinc Finger Protein GLI1

2014
Hedgehog pathway plays a vital role in HIV-induced epithelial-mesenchymal transition of podocyte.
    Experimental cell research, 2017, 03-15, Volume: 352, Issue:2

    Topics: Animals; Cell Line; Epithelial-Mesenchymal Transition; Female; Hedgehog Proteins; HIV; Humans; Male; Mice; Podocytes; Pyridines; Thiophenes

2017
Glioma-Associated Oncogene Homolog Inhibitors Have the Potential of Suppressing Cancer Stem Cells of Breast Cancer.
    International journal of molecular sciences, 2018, May-05, Volume: 19, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Pyridines; Signal Transduction; Thiophenes; Zinc Finger Protein GLI1

2018
The hedgehog and Wnt/β-catenin system machinery mediate myofibroblast differentiation of LR-MSCs in pulmonary fibrogenesis.
    Cell death & disease, 2018, 05-29, Volume: 9, Issue:6

    Topics: Animals; Bleomycin; Cell Differentiation; Frizzled Receptors; Hedgehog Proteins; Idiopathic Pulmonary Fibrosis; Lung; Mesenchymal Stem Cells; Mice; Models, Biological; Myofibroblasts; Pyridines; Thiophenes; Wnt Signaling Pathway; Zinc Finger Protein GLI1

2018
Elucidation of mechanism for host response to VHSV infection at varying temperatures in vitro and in vivo through proteomic analysis.
    Fish & shellfish immunology, 2019, Volume: 88

    Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cyprinidae; Gene Expression; Hemorrhagic Septicemia, Viral; Novirhabdovirus; Proteome; Pyridines; Temperature; Thiophenes; Zebrafish; Zinc Finger Protein Gli2

2019
Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, Volume: 311-312

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Liberation; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Mesenchymal Stem Cells; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Nanoparticles; Osteogenesis; Polymers; Pyridines; Thiophenes; Zinc Finger Protein Gli2

2019
Tuning Ligand Density To Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction.
    ACS nano, 2020, 01-28, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Humans; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles; Optical Imaging; Particle Size; Polymers; Pyridines; Surface Properties; Thiophenes; X-Ray Microtomography

2020
Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of
    International journal of molecular sciences, 2020, Apr-15, Volume: 21, Issue:8

    Topics: Aging; Animals; Cell Survival; Cells, Cultured; Gene Expression Regulation, Developmental; Hedgehog Proteins; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteoclasts; Osteogenesis; Osteoporosis; Pyridines; Pyrimidines; Receptor, Macrophage Colony-Stimulating Factor; Signal Transduction; Smoothened Receptor; Thiophenes; Up-Regulation; Veratrum Alkaloids; X-Ray Microtomography; Zinc Finger Protein GLI1; Zinc Finger Protein Gli2

2020
3D Bone Morphology Alters Gene Expression, Motility, and Drug Responses in Bone Metastatic Tumor Cells.
    International journal of molecular sciences, 2020, Sep-21, Volume: 21, Issue:18

    Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Models, Biological; Neoplasm Metastasis; Neoplasm Proteins; Pyridines; Thiophenes; Tissue Scaffolds

2020
Knockdown of E-cadherin induces cancer stem-cell-like phenotype and drug resistance in cervical cancer cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2021, Volume: 99, Issue:5

    Topics: Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Female; Humans; Neoplastic Stem Cells; Phenotype; Pyridines; RNA, Small Interfering; Thiophenes; Uterine Cervical Neoplasms; Veratrum Alkaloids

2021