Page last updated: 2024-08-18

thiophenes and ertiprotafib

thiophenes has been researched along with ertiprotafib in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (60.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	1 (20.00)	2.80

Authors

Authors	Studies
Erbe, DV; Furey, S; Harding, K; Klaman, LD; Kung, L; Qadri, A; Stolz, L; Tam, M; Tobin, JF; Wang, S; Xing, Y; Zhang, YL	1
Chandrasekaran, A; Jordan, R; Li, H; Markiewicz, V; Scatina, J; Shen, L; Tong, Z; Xiang, Q	1
Bhattarai, BR; Cho, H; Choi, JK; Shrestha, S	1
Liu, JZ; Nie, F; Tang, YB; Tian, JY; Xiao, Z; Yang, Y; Ye, F; Yin, W; Zhang, SE	1
Kumar, GS; Page, R; Peti, W	1

Trials

1 trial(s) available for thiophenes and ertiprotafib

Article	Year
PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta). Bioorganic & medicinal chemistry letters, 2007, May-15, Volume: 17, Issue:10 Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; I-kappa B Kinase; Phenylpropionates; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Thiophenes	2007

Article

Year

PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta).

Bioorganic & medicinal chemistry letters, 2007, May-15, Volume: 17, Issue:10

Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; I-kappa B Kinase; Phenylpropionates; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Thiophenes

2007

Other Studies

4 other study(ies) available for thiophenes and ertiprotafib

Article	Year
Ertiprotafib improves glycemic control and lowers lipids via multiple mechanisms. Molecular pharmacology, 2005, Volume: 67, Issue:1 Topics: Adipocytes; Animals; Blood Glucose; Cell Differentiation; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Kinetics; Lipids; Male; Mice; Mice, Obese; Phenylpropionates; PPAR alpha; PPAR gamma; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Recombinant Proteins; Thiophenes; Triglycerides	2005
Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes. Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:1 Topics: Animals; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; Female; Glucuronosyltransferase; Hepatocytes; Humans; Hydroxyurea; Hypoglycemic Agents; Liver; Male; Microsomes, Liver; Organ Size; Peroxisomes; Phenylpropionates; Rats; RNA, Messenger; Thiazolidinediones; Thiophenes; Thyroid Gland	2007
Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib. Bioorganic & medicinal chemistry letters, 2013, Dec-01, Volume: 23, Issue:23 Topics: Drug Design; Enzyme Inhibitors; Humans; Models, Molecular; Phenylpropionates; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Thiophenes	2013
The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib. PloS one, 2020, Volume: 15, Issue:10 Topics: Catalytic Domain; Enzyme Inhibitors; Humans; Phenylpropionates; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Thiophenes	2020