Page last updated: 2024-08-18

thiophenes and eprosartan

thiophenes has been researched along with eprosartan in 257 studies

Research

Studies (257)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's62 (24.12)18.2507
2000's154 (59.92)29.6817
2010's33 (12.84)24.3611
2020's8 (3.11)2.80

Authors

AuthorsStudies
Benfield, P; Chiu, AT; Herblin, WF; Smith, RD; Timmermans, PB; Wong, PC1
Aiyar, N; Edwards, RM; Ezekiel, M; Griffin, E; Keenan, RM; Ohlstein, EH; Ruffolo, RR; Weidley, EF; Weinstock, J1
Brooks, DP; DePalma, PD; Ruffolo, RR1
Brooks, DP; Edwards, RM; Gellai, M; Jugus, J; Ohlstein, EH; Ruffolo, RR; Sulpizio, A; Vickery, L; Weinstock, J1
Aiyar, N; Edwards, RM; Hill, DT; Keenan, RM; Stack, EJ; Weidley, EF; Weinstock, J1
Brooks, DP; Wang, YX1
Brooks, DP; Edwards, RM; Fredrickson, TA; Gellai, M; Ruffolo, RR; Weinstock, J1
Finkelstein, JA; Franz, RG; Gaitanopoulos, DE; Girard, GR; Gleason, JG; Hempel, J; Hill, DT; Keenan, RM; Samanen, J; Weinstock, J1
Hjorth, SA; Schambye, HT; Schwartz, TW; Weinstock, J1
Bauer, JH; Reams, GP1
Arleth, AJ; Ohlstein, EH; Storer, BL; Sung, CP1
Ganter, RC; Hondrelis, J; Matsoukas, J; Moore, DM; Moore, GJ; Smith, JR; Wahhab, A1
Brooks, DP; DePalma, PD; Fredrickson, TA; Ruffolo, RR; Spielman, WS1
Aiyar, N; Edwards, R; Griffin, E; Nambi, P; Samanen, J; Weinstock, J1
Aiyar, N; Bergsma, DJ; Edwards, R; Griffin, E; Heys, R; Shu, A; Weinstock, J1
Finkelstein, JA; Franz, RG; Gaitanopoulos, DE; Girard, GR; Hill, DT; Keenan, RM; Morgan, TM; Peishoff, CE; Samanen, JM; Weinstock, J1
Edwards, RM; Stack, EJ; Trizna, W; Weinstock, J1
Gao, XP; Olopade, CO; Rubinstein, I; Suzuki, H1
Boike, SC; DeCherney, GS; Freed, MI; Ilson, BE; Jones, BA; Jorkasky, DK; Martin, DE1
Boike, SC; Citerone, D; Ilson, B; Jorkasky, DK; Martin, DE; Tenero, D; Tompson, D1
De'Oliveira, JM; Fisher, ND; Hollenberg, NK; Price, DA1
Blum, RA; Boike, SC; Etheredge, R; Ilson, B; Jorkasky, DK; Kazierad, DJ; Martin, DE; Tenero, DM1
Brooks, DP; Feuerstein, GZ; Ohlstein, EH; Ruffolo, RR1
Boike, SC; Boyle, DA; Carr, AM; Ilson, BE; Jorkasky, DK; Lundberg, DE; Martin, DE; Tenero, DM1
Boike, SC; Chapelsky, MC; Ilson, B; Jorkasky, DK; Martin, DE; Tenero, D; Zariffa, N1
Boike, SC; Freed, MI; Ilson, BE; Jorkasky, DK; Martin, DE; Zariffa, N1
Balfour, JA; McClellan, KJ1
Boike, SC; Chapelsky, MC; Etheredge, R; Ilson, BE; Jorkasky, DK; Martin, DE; Tenero, DM1
Boike, SC; Ilson, BE; Jorkasky, DK; Martin, DE1
Cyronak, MJ; Knox, S; Lundberg, DE; Person, CR1
Mayeux, PR; Zhang, C1
Boike, S; Forrest, A; Ilson, B; Jorkasky, DK; Kazierad, DJ; Martin, DE; Zariffa, N1
Boike, S; Boyle, D; Ilson, B; Jorkasky, D; Jushchyshyn, J; Lundberg, D; Martin, D; Tenero, D; Zariffa, N1
Boike, SC; Ilson, B; Jorkasky, DK; Martin, DE; Miller, AK; Tenero, DM; Zariffa, N1
Abassi, Z; Brodsky, S; Feuerstein, GZ; Gurbanov, K; Hoffman, A; Ruffolo, RR; Winaver, J1
Oparil, S1
Chung, O; Csikós, T; Unger, T1
Hedner, T; Himmelmann, A1
Hollenberg, NK2
Bottorff, MB; Tenero, DM1
Blum, RA; Kazierad, DJ; Tenero, DM1
Hollenberg, NK; Sica, DA1
Weber, M1
Gavras, H; Gavras, I2
Sica, DA2
Diamond, JA; Gharavi, A; Henzlova, MJ; Machac, J; Phillips, RA; Roychoudhury, D; Travis, A1
Argenziano, L; Trimarco, B1
Levine, B2
Gradman, AH; Gray, J; Maggiacomo, F; Punzi, H; White, WB1
Ilson, BE; Jorkasky, DK; Kovacs, SJ; Martin, DE; Tenero, DM1
Elliott, WJ1
Dietze, GJ; Henriksen, EJ; Jacob, S; Kinnick, TR; Schmit, MB; Youngblood, EB1
Buño, A; Dal-Ré, R; Mateos, F; Ortega, R; Puig, JG; Rodriguez, F1
Brooks, DP; Gandhi, M; Meyer, TW1
Sega, R1
Hedner, T2
Brooks, DP; Ruffolo, RR1
Shusterman, NH1
Brooks, DP; Ohlstein, EH; Ruffolo, RR1
Duddu, SP; Grant, DJ; Sheng, J; Venkatesh, GM1
Gremmler, B; Kunert, M; Schleiting, H; Ulbricht, LJ1
DelGrande, D; Shetty, SS1
Kiukaanniemi, K; Pelkonen, O; Taavitsainen, P1
Grossman, E; Messerli, FH; Neutel, JM1
Hollenberg, NK; Laffel, LM; Lansang, MC; Osei, SY; Price, DA1
Foster, RH; Plosker, GL1
Brooks, DP; Contino, LC; Grygielko, E; Laping, NJ; Olson, BA; Wong, VY1
Benkel, M; Maisch, B; Rupp, H1
Chikhladze, NM1
Caballero, R; Delpón, E; González, T; Longobardo, M; Tamargo, J; Valenzuela, C1
Vidt, DG1
Ramahi, TM1
Dargie, HJ; Farmer, R; McDonagh, TA; McMurray, JJ; Morton, JJ; Murdoch, DR1
Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP; van Meegen, JR; Verdouw, PD1
Barone, FC; Brooks, DP; Campbell, WG; Chandra, S; Coatney, RW; Contino, LC; Nelson, AH; Ohlstein, EH; Sarkar, SK; Willette, RN1
Guimarães, S; Loio, A; Moura, D; Pinheiro, H; Tavares, P1
Bahner, U; Elsner, D; Jandeleit-Dahm, K; Kirst, I; Muders, F; Palkovits, M1
Giatas, N; Golic Grdadolnik, S; Iliodromitis, EK; Keivish, T; Kremastinos, DT; Matsoukas, J; Mavromoustakos, T; Mutule, I; Polevaya, L; Roumelioti, P; Vlahakos, DV; Zoumboulakis, P1
Magometschnigg, D1
Gavras, HP1
Krum, H1
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1
Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP; Verdouw, PD1
Breeze, E; Donoghue, MD; Fletcher, AE; Rake, EC1
Breeze, E; Fletcher, AE; Rake, EC1
Anwar, YA; Mansoor, GA; Sica, DA; White, WB1
Jäger, B; Prichard, B; Ruilope, L1
McInnes, GT1
Grove, KL; Smith, MS; Speth, RC1
Akesolo, U; Alonso, RM; González, L; Jiménez, RM1
Grdadolnik, SG; Matsoukas, J; Mavromoustakos, T; Zoumpoulakis, P1
Jäger, B; Sachse, A; Verboom, CN1
Khan, BV; Khan, QA; Lauten, WB; Navalkar, S; Parthasarathy, S; Rahman, ST1
Al'-Iazidi, MA; Barsukov, AV; Konev, AV; Kulikov, AN; Shustov, SB1
Abrahamsen, CT; Barone, FC; Brooks, DP; Campbell, WG; Contino, LC; Edwards, RM; Grygielko, ET; Laping, NJ; Nelson, AH; Pullen, MA1
Delles, C; Fleischmann, I; Jacobi, J; John, S; Schmieder, RE1
Balt, JC; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA2
Rapi, J1
Böhm, M; Sachse, A1
Delles, C; Gekle, M; John, S; Schmieder, RE; Schneider, MP1
Puig, JG; Ruilope, LM; Torres, R1
Gurevich, MA1
Castells, X; Cereza, G; Laporte, JR; Pedrós, C; Rodoreda, I1
Belavina, NI; Griabina, NA; Koren'kov, VV; Markova, LI; Radzevich, AE; Zharova, OIu1
Nebieridze, DV; Oganov, RG1
Jäger, B; Ruilope, L1
Mancini, GB1
Anagnostopoulos, PV; Chaudhry, PA; Goldstein, S; Gupta, RC; Mishima, T; Nass, O; Rostogi, S; Sabbah, HN; Sharov, VG; Suzuki, G; Tanhehco, EJ; Todor, A1
Barin, ES; Gilfillan, KL; Stokes, GS1
Krovat, EM; Langer, T1
Frank, H; Heusser, K; Schmieder, RE; Schobel, HP; Vitkowsky, J1
Bernardino, JI; Bueso, TS; Jiménez, RT; López, MA; Puig, JG1
Schieffer, B; Schmidt, B1
Terra, SG1
Heusser, K; Raasch, W; Schmieder, RE; Schobel, HP; Vitkovsky, J1
Heusser, K; Schmieder, RE; Schobel, HP; Vitkovsky, J1
Jermendy, G; Matos, L; Winkler, G1
Sidorenko, GI1
Dominiak, P; Häuser, W1
Kossmehl, P; Kreutz, R; Neumayer, HH; Paul, M; Rothermund, L1
Boĭko, AN; Gusev, EI; Makarov, AN; Martynov, MIu; Petukhov, EB1
Balt, JC; Belterman, CN; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA1
Rupp, H2
Koren'kov, VV; Markova, LI; Radzevich, AE; Shakhova, NI1
Metlitskaia, EV; Petrik, ES; Shalaev, SV; Shanaurina, NV; Teffenberg, DV; Volkova, SIu1
Ivanova, NA; Preobrazhenskiĭ, DV; Sidorenko, BA; Soplevenko, AV; Stetsenko, TM1
Punzi, CF; Punzi, HA1
Anderson, K; Angermann, CE; Barone, FC; Behr, TM; Berova, M; Coatney, RW; Sackner-Bernstein, JD; Willette, RN1
Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA1
Clasen, R; Janke, J; Kintscher, U; Schupp, M; Unger, T1
Alonso, FJ; Blanco, J; Gamero, MJ; Jiménez Pérez, JL; Masot, J; Matilla, C; Nieto, J; Robles, NR; Romero, F; Velasco, J1
Chen, Y; Currie, RW; Ross, BM1
Ciccarelli, L; Derosa, G; Fogari, R; Mugellini, A; Ragonesi, PD1
Charng, MJ; Ding, PY; Leu, HB1
Aznar, J; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Munoz, A1
Hatzizacharias, A; Krespi, P; Makris, TK; Papadopoulos, DP; Stavroulakis, G; Tsoukala, C; Votteas, VE; Zilidis, A1
Christensen, M; Ibsen, H; Worck, R1
Lapina, EIa; Makarova, SV; Praskurnichiĭ, EA; Samartsev, GA; Shevchenko, OP1
Blankestijn, PJ; Koomans, HA; Ligtenberg, G; Neumann, J; Oey, L1
Blann, AD; Caine, GJ; Chatterjee, S; Gibson, J; Hope-Ross, M; Lip, GY; Lip, PL1
Arcos, E; de la Sierra, A; Lopez, JS; Munoz, A; Relats, J2
Campbell, DJ; Esler, MD; Krum, H1
Alamo, C; López-Muñoz, F; Martín-Agueda, B; Robles, NR2
Berger, J; Diener, HC; Dominiak, P; Hammersen, F; Kulschewski, A; Lüders, S; Plate, K; Schrader, J; Zidek, W1
Abassi, Z; Abbasi, A; Golomb, E; Hochberg, I; Hoffman, A; Karram, T; Keidar, S; Winaver, J1
foniakin, AV; Geraskina, LA; Konradi, VV; Sharypova, TN; Suslina, ZA1
Abashidze, TB; Gorgoshidze, ML1
Basile, J; Bloch, MJ1
Chai, W; Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP1
Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K1
Arosio, E; De Marchi, S; Lechi, A; Prior, M; Rigoni, A1
Robins, GW; Scott, LJ1
Campbell, DJ; Esler, M; Krum, H; Lambert, E; Windebank, E1
Clemenz, M; Gineste, R; Helleboid, S; Hennuyer, N; Janke, J; Kintscher, U; Ruiz, P; Schupp, M; Staels, B; Unger, T; Witt, H1
Boulanger, JM; Hill, MD1
Strauss, MH; Verma, S1
Brown, MJ; Cockcroft, JR; Dhakam, Z; McEniery, CM; Wilkinson, IB1
Alonso, RM; Ferreirós, N; Iriarte, G; Jiménez, RM; Ortíz, E2
Ametov, AS; Demidova, TIu; Kosykh, SA1
Cierco, M; del Rosario Garrido, M; Gutierrez, A; Israel, A; Zavala, LE1
Boysen, G; Hornnes, N; Larsen, K1
Feldman, RD1
Conter, HS; McKay, DW; Reiz, RJ1
Chilvers, M; Reiz, RJ; Teitelbaum, I1
Johnston, SC1
Frerichs, A; Frieg, R; Hahnheiser, D; Hammersen, F; Kulschewski, A; Lüders, S; Reich, G; Schnieders, M; Schrader, J; Schrandt, G1
At'kova, EO; Gutnikova, OV; Tsfasman, AZ1
de la Sierra, A1
Hanon, O; Negre-Pages, L; Pathak, A; Sevenier, F1
Chen, WL; Chu, NN; Li, XN; Liu, GY; Xu, HR; Yu, C2
Buus, NH; Christensen, KL; Larsen, ML; Mathiassen, ON; Mulvany, MJ1
de Leeuw, PW; Dielis, AW; Hamulyák, K; Houben, AJ; Kroon, AA; Smid, M; Spronk, HM; Ten Cate, H1
Cierco, M; Garrido, MR; Gutiérrez, A; Israel, A; Zavala, LE1
Aulakh, GK; Singh, M; Sodhi, RK1
Gremmler, B; Kisters, K; Kunert, M; Schleiting, H; Ulbricht, LJ1
Kaliuzhin, VV; Kaliuzhina, EV; Kolesnikov, RN; Konaplev, DI; Solovtsev, MA; Surkova, LG; Zibnitskaia, LI1
Ram, CV; Rudmann, MA1
de la Sierra, A; Ram, CV1
Ram, CV1
Shlyakhto, E1
Angus, JA; Grange, RL; North, AJ; Schiesser, CH; Ziogas, J1
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M1
Bech, JN; Lauridsen, TG; Pedersen, EB; Vase, H1
Beltrán, B; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Muñoz, A; Ruiz-Aja, S1
Makarova, SV; Praskurnichiĭ, EA; Savel'eva, SA; Shevchenko, OP; Zhukova, VA1
Kumova, TA; Medvedev, IN; Simonenko, VB1
El-Yazbi, FA; Hammud, HH; Sonji, GM; Sonji, NM1
Berrou, JP; Goch, JH; Hanon, O; Nádházi, Z; Negre-Pages, L; Pathak, A; Petrella, R; Sedefdjian, A; Sévenier, F; Shlyakhto, EV1
Blankestijn, PJ; Rupp, H1
Albert, DH; Banfor, PN; Cox, BF; Davidsen, SK; Franklin, PH; Fryer, RM; Gintant, GA; Larson, KJ; Noonan, WT; Segreti, JA; Tapang, P; Widomski, DL1
Calderone, A; Gillis, MA; Gutkowska, J; Jankowski, M; Menaouar, A; Mukaddam-Daher, S; Paquette, PA; Shi, YF; Tardif, JC1
Beltrán, B; Dasi, F; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Muñoz, A1
Dowlatshahi, D; Hill, MD1
Diener, HC; Gradl, B; Greiner, W; Jönsson, B; Lindgren, P; Lüders, S; Schrader, J; Schwander, B; Villar, FA; Zöllner, Y1
Domínguez-Gil, A; Gregori, JA; Nuñez, JF1
Enikeev, AKh; Kolomoets, NM; Zamotaev, IuN1
Derosa, G; Ferrari, I; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A1
Pan, Y; Sun, C; Wang, D; Wu, J1
Plosker, GL1
Hartog, JW; Jaarsma, W; Miyata, T; Plokker, HW; Schalkwijk, CG; Smit, AJ; van de Wal, RM; van Veldhuisen, DJ; van Wijk, LM; Voors, AA1
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J1
Hartog, JW; Hummel, YM; Jaarsma, W; Plokker, TW; van de Wal, RM; van Veldhuisen, DJ; Vijn, RG; Voors, AA1
Ambrosioni, E; Bombelli, M; Cerasola, G; Cipollone, F; Ferri, C; Grazioli, I; Leprotti, C; Mancia, G; Melzi, G; Mugellini, A; Mulè, G; Palasciano, G; Salvetti, A; Trimarco, B1
Kahner-Gröne, S; Köneke, D; Marggraf, K; Nüdling, S; Palissa, H1
Li, H; Shi, D; Shi, XY; Xu, FY; Yang, B; Zou, Z1
Berrou, JP; Choueiry, P; Eid, E; Ismail, A; Pathak, A; Radaideh, GA; Sedefdjian, A; Sévenier, F1
De Backer, G; Goudev, AR; Pathak, A; Petrella, RJ; Radaideh, GA; Rynkiewicz, A1
Berrou, JP; Konradi, AO; Pathak, A; Petrella, RJ; Sedefdjian, A; Shlyakhto, E1
Hacioğlu, F; Onal, A1
Zamotaev, IuN1
Fullana-Monllor, J; Martinez-Moragón, E; Pérez-Lluna, L1
Berrou, JP; Goudev, A; Pathak, A1
Ackaert, O; Koopmans, RP; Mathôt, RA; Ploeger, BA; Snelder, N; van Hest, RM; van Rijn-Bikker, PC1
Hanon, O; Lee, YS; Pathak, A1
Grankina, VIu; Kaliuzhin, VV; Kaliuzhina, EV; Sazonov, ÉA; Sibireva, OF; Tkalich, LM; Urazova, OI; Zibnitskaia, LI1
De Backer, G; Gill, DP; Petrella, RJ; Tremblay, G1
Dohmen, PM; Konertz, W; Modersohn, D; Patil, NP; Sabashnikov, A; Weymann, A1
Asner, R; Bayer, A; Kopf, W; Letzel, M; Schüssler, W; Sengl, M; Weiß, K1
Huo, X; Liu, K; Liu, Q; Meng, Q; Sun, H; Sun, P; Wang, C; Zhang, A1
Devrukhakar, PS; Gaitonde, VD; Kalariya, PD; Kumar Talluri, MV; Srinivas, R1
Bao, X; Chen, J; Ding, X; Wang, C; Wang, W; Wang, Y; Zhang, F; Zhou, J1
Chen, C; Du, J; Li, HH; Meng, Y; Tian, C1
Heeba, GH; Mahmoud, ME; Morsy, MA1
Hehemann, K; Maier, H; Vieth, M1
Bao, X; Ding, X; Ding, Y; Li, M; Wang, C; Wang, W; Wu, Y; Xiong, H; Yang, T; Zhou, J1
Ah, YM; Choi, KH; Choi, YJ; Han, N; Kim, B; Kong, J; Lee, HY; Lee, JY; Oh, JM; Shin, WG; Yu, YM1
de Leeuw, PW; Houben, AJ; Kroon, AA; van Twist, DJ1
Dangre, P; Dhole, S; Gilhotra, R1
Ostroumova, OD; Pervichko, EI; Zinchenko, YP1
Karnik, SS; Node, K; Takezako, T; Unal, H1
Pokharkar, V; Shekhawat, P1
Abdelsalam, RA; Haddad, GM; Marghany, KA1
Leonova, GN; Lubova, VA; Maistrovskaya, OS1
Anitha, P; Babu, D; Gayathri, R; Mohan, S; Ramkanth, S1
Al-Shorbagy, M; El-Naggar, R; El-Yamany, MF; Fahmy, MIM; Hegazy, AAE; Saad, MAE; Sayed, RH1
Majer, J; Masajtis-Zagajewska, A; Nowicki, M1
Abdul-Aziz, AA; Elshehawy, AA; Koutb, F; Mehany, H; Shaban, NZ; Zaki, MM1
Ahad, A; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Bin Jardan, YA; Hassan, MZ; Raish, M1
Berto-Junior, C; Guimarães-Nobre, CC; Mendonça-Reis, E; Miranda-Alves, L; Teixeira-Alves, LR1

Reviews

44 review(s) available for thiophenes and eprosartan

ArticleYear
Angiotensin II receptors and functional correlates.
    American journal of hypertension, 1992, Volume: 5, Issue:12 Pt 2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Imidazoles; Losartan; Pyridines; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Thiophenes

1992
The angiotensin II type 1 receptor antagonists. A new class of antihypertensive drugs.
    Archives of internal medicine, 1995, Jul-10, Volume: 155, Issue:13

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Pyridines; Quinolines; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

1995
Eprosartan.
    Drugs, 1998, Volume: 55, Issue:5

    Topics: Acrylates; Antihypertensive Agents; Humans; Imidazoles; Randomized Controlled Trials as Topic; Thiophenes

1998
Angiotensin II receptor pharmacology and AT1-receptor blockers.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes

1999
Pharmacokinetics of eprosartan in healthy subjects, patients with hypertension, and special populations.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Absorption; Acrylates; Age Factors; Antihypertensive Agents; Biological Availability; Clinical Trials, Phase III as Topic; Humans; Hypertension; Imidazoles; Sex Factors; Thiophenes

1999
A review of eprosartan pharmacokinetic and pharmacodynamic drug interaction studies.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Drug Interactions; Humans; Imidazoles; Randomized Controlled Trials as Topic; Thiophenes

1999
The renal profile of eprosartan.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Imidazoles; Male; Randomized Controlled Trials as Topic; Thiophenes

1999
Clinical efficacy of eprosartan.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Imidazoles; Randomized Controlled Trials as Topic; Thiophenes

1999
Safety and tolerability of eprosartan.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Acrylates; Antihypertensive Agents; Clinical Trials as Topic; Drug Tolerance; Humans; Hypertension; Imidazoles; Thiophenes

1999
Management of hypertension: the advent of a new angiotensin II receptor antagonist.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1999, Volume: 17, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Enalapril; Humans; Hypertension; Imidazoles; Survival Rate; Thiophenes; Treatment Outcome

1999
Pharmacological mechanism of angiotensin II receptor antagonists: implications for the treatment of elevated systolic blood pressure.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1999, Volume: 17, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Sympathetic Nervous System; Systole; Thiophenes; Treatment Outcome; Vascular Resistance

1999
Safety and efficacy of eprosartan, a new angiotensin II receptor blocker.
    American heart journal, 1999, Volume: 138, Issue:3 Pt 2

    Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Drug Interactions; Humans; Hypertension; Imidazoles; Thiophenes

1999
Pharmacology of eprosartan, an angiotensin II receptor antagonist: exploring hypotheses from clinical data.
    American heart journal, 1999, Volume: 138, Issue:3 Pt 2

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hypertension; Imidazoles; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes

1999
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
    Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13

    Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes

2000
Eprosartan: a review of its use in the management of hypertension.
    Drugs, 2000, Volume: 60, Issue:1

    Topics: Acrylates; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Thiophenes

2000
Control of cardiomyocyte gene expression as drug target.
    Molecular and cellular biochemistry, 2000, Volume: 212, Issue:1-2

    Topics: Acrylates; Amino Acid Sequence; Animals; Antihypertensive Agents; Calcium-Transporting ATPases; Catecholamines; Gene Expression Regulation; Heart Failure; Humans; Hypertension; Imidazoles; Molecular Sequence Data; Myocardium; Myosin Heavy Chains; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sequence Alignment; Sequence Homology, Amino Acid; Thiophenes

2000
[Prospects for pharmacological effects on renin-angiotensin and sympathetic nervous systems in patients with arterial hypertension].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:12

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes

2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.
    Postgraduate medicine, 2001, Volume: 109, Issue:4

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan

2001
[Angiotensin receptor blockers--significance for the therapy of hypertension].
    Wiener medizinische Wochenschrift (1946), 2001, Volume: 151, Issue:7-8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Prodrugs; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Valine; Valsartan

2001
Issues in hypertension: drug tolerability and special populations.
    American journal of hypertension, 2001, Volume: 14, Issue:7 Pt 2

    Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Interactions; Humans; Hypertension; Imidazoles; Middle Aged; Patient Compliance; Receptors, Angiotensin; Thiophenes; United States

2001
Pharmacology and clinical efficacy of angiotensin receptor blockers.
    American journal of hypertension, 2001, Volume: 14, Issue:7 Pt 2

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Treatment Outcome

2001
Differentiation in the angiotensin II receptor 1 blocker class on autonomic function.
    Current hypertension reports, 2001, Volume: 3 Suppl 1

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autonomic Nervous System Diseases; Heart Rate; Humans; Imidazoles; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes

2001
Potential of the angiotensin II receptor 1 blocker eprosartan in the management of patients with hypertension or heart failure.
    Current hypertension reports, 2001, Volume: 3 Suppl 1

    Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Heart Failure; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Treatment Outcome

2001
Angiotensin II antagonists in systolic blood pressure control.
    Hospital medicine (London, England : 1998), 2001, Volume: 62, Issue:12

    Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Blood Pressure; Delivery of Health Care; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Systole; Thiophenes

2001
[Irbesartan: a new possibility in the treatment of hypertension].
    Orvosi hetilap, 2002, May-26, Volume: 143, Issue:21

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2002
Safety and tolerability of eprosartan in combination with hydrochlorothiazide.
    Drug safety, 2002, Volume: 25, Issue:8

    Topics: Acrylates; Age Factors; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Thiophenes

2002
The clinical profile of the angiotensin II receptor blocker eprosartan.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2002, Volume: 20, Issue:5

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Thiophenes

2002
[Policy of antihypertensive therapy in arterial hypertension in the elderly. II].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:9

    Topics: Acrylates; Adrenergic alpha-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Perindopril; Risk Factors; Sex Factors; Sodium Chloride Symporter Inhibitors; Thiophenes

2002
Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation.
    The Canadian journal of cardiology, 2002, Volume: 18, Issue:12

    Topics: Acrylates; Aged; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Coronary Artery Disease; Data Interpretation, Statistical; Diabetes Mellitus; E-Selectin; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Thiophenes; Vasculitis

2002
Clinical profile of eprosartan.
    Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:6

    Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Humans; Imidazoles; Renin-Angiotensin System; Thiophenes; Treatment Outcome

2002
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2

2003
[Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology].
    Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2003
[Neurocirculatory dystonia (does this disease exist?)].
    Kardiologiia, 2003, Volume: 43, Issue:10

    Topics: Acrylates; Adolescent; Adult; Antihypertensive Agents; Child; Clinical Trials as Topic; Diagnosis, Differential; Female; Humans; Imidazoles; Male; Neurocirculatory Asthenia; Psychotherapy; Stress, Psychological; Thiophenes

2003
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].
    Kardiologiia, 2004, Volume: 44, Issue:1

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan

2004
Eprosartan: a review of its use in the management of hypertension.
    Drugs, 2005, Volume: 65, Issue:16

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Imidazoles; Thiophenes

2005
Effects of eprosartan on target organ protection.
    Vascular health and risk management, 2006, Volume: 2, Issue:1

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Neuroprotective Agents; Nitrendipine; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Research Design; Risk Factors; Stroke; Thiophenes; Treatment Outcome

2006
An update on non-peptide angiotensin receptor antagonists and related RAAS modulators.
    Life sciences, 2007, Aug-02, Volume: 81, Issue:8

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Endothelin Receptor Antagonists; Humans; Hypertension; Imidazoles; Losartan; Protease Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2; Renin; Renin-Angiotensin System; Thiophenes

2007
Unique dual mechanism of action of eprosartan: effects on systolic blood pressure, pulse pressure, risk of stroke and cognitive decline.
    Expert review of cardiovascular therapy, 2007, Volume: 5, Issue:6

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Cognition Disorders; Female; Humans; Hypertension; Imidazoles; Male; Sensitivity and Specificity; Severity of Illness Index; Stroke; Survival Analysis; Systole; Thiophenes; Treatment Outcome

2007
Angiotensin blockade with eprosartan: vascular and functional implications.
    Current medical research and opinion, 2007, Volume: 23 Suppl 5

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atherosclerosis; Humans; Imidazoles; Kidney Diseases; Platelet Aggregation; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Ventricular Dysfunction, Left

2007
Observational Study on Cognitive function And systolic blood pressure Reduction (OSCAR): preliminary analysis of 6-month data from > 10,000 patients and review of the literature.
    Current medical research and opinion, 2007, Volume: 23 Suppl 5

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Animals; Cognition Disorders; Dementia, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Rats; Stroke; Thiophenes

2007
Risk reduction by preventing stroke: need for blockade of angiotensin II and catecholamines?
    Current medical research and opinion, 2007, Volume: 23 Suppl 5

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Catecholamines; Humans; Hypertension; Imidazoles; Norepinephrine; Stroke; Tetrazoles; Thiophenes; Valine; Valsartan

2007
Clinical profile of eprosartan: a different angiotensin II receptor blocker.
    Cardiovascular & hematological agents in medicinal chemistry, 2008, Volume: 6, Issue:4

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension; Imidazoles; Kidney Diseases; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes

2008
Eprosartan: a review of its use in hypertension.
    Drugs, 2009, Volume: 69, Issue:17

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Clinical Trials as Topic; Cough; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Nitrendipine; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Recurrence; Risk Factors; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome

2009
Antihypertensive effects and safety of eprosartan: a meta-analysis of randomized controlled trials.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:2

    Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Randomized Controlled Trials as Topic; Thiophenes

2012

Trials

77 trial(s) available for thiophenes and eprosartan

ArticleYear
Eprosartan, an angiotensin II receptor antagonist, does not affect the pharmacodynamics of glyburide in patients with type II diabetes mellitus.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Interactions; Female; Glyburide; Humans; Hypoglycemic Agents; Imidazoles; Male; Middle Aged; Sweating; Thiophenes

1997
Lack of effect of eprosartan on the single dose pharmacokinetics of orally administered digoxin in healthy male volunteers.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: Acrylates; Administration, Oral; Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Digoxin; Drug Interactions; Humans; Imidazoles; Iodine Radioisotopes; Isotope Labeling; Male; Radioimmunoassay; Receptors, Angiotensin; Thiophenes

1997
Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:4

    Topics: Acrylates; Adult; Antifungal Agents; Antihypertensive Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Fluconazole; Humans; Imidazoles; Losartan; Male; Middle Aged; Reference Values; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tetrazoles; Thiophenes; Time Factors

1997
Effect of ranitidine on the pharmacokinetics of orally administered eprosartan, an angiotensin II antagonist, in healthy male volunteers.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3

    Topics: Acrylates; Administration, Oral; Adult; Angiotensin II; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Histamine H2 Antagonists; Humans; Imidazoles; Male; Ranitidine; Thiophenes

1998
A dose-response study to assess the renal hemodynamic, vascular, and hormonal effects of eprosartan, an angiotensin II AT1-receptor antagonist, in sodium-replete healthy men.
    Clinical pharmacology and therapeutics, 1998, Volume: 63, Issue:4

    Topics: Acrylates; Adult; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Humans; Imidazoles; Male; Potassium, Dietary; Reference Values; Renal Circulation; Sodium, Dietary; Thiophenes; Time Factors

1998
A dose proportionality study of eprosartan in healthy male volunteers.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:1

    Topics: Acrylates; Adult; Antihypertensive Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Imidazoles; Male; Thiophenes

1998
The effects of eprosartan, an angiotensin II AT1 receptor antagonist, on uric acid excretion in patients with mild to moderate essential hypertension.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:5

    Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Creatinine; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Imidazoles; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Thiophenes; Uric Acid

1998
Eprosartan does not affect the pharmacodynamics of warfarin.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:7

    Topics: Acrylates; Adult; Anticoagulants; Antihypertensive Agents; Double-Blind Method; Drug Interactions; Humans; Imidazoles; International Normalized Ratio; Male; Middle Aged; Thiophenes; Warfarin

1998
Pharmacokinetics of intravenously and orally administered eprosartan in healthy males: absolute bioavailability and effect of food.
    Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:6

    Topics: Acrylates; Administration, Oral; Adult; Analysis of Variance; Antihypertensive Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Dietary Fats; Food-Drug Interactions; Half-Life; Humans; Imidazoles; Injections, Intravenous; Male; Thiophenes

1998
The efficacy and tolerance of one or two daily doses of eprosartan in essential hypertension. The Eprosartan Multinational Study Group.
    Journal of hypertension, 1999, Volume: 17, Issue:1

    Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes; Treatment Outcome

1999
Effect of long-term eprosartan versus enalapril antihypertensive therapy on left ventricular mass and coronary flow reserve in stage I-II hypertension. Eprosartan Study Group.
    Current medical research and opinion, 1999, Volume: 15, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Circulation; Double-Blind Method; Enalapril; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Thiophenes

1999
Effect of eprosartan and enalapril in the treatment of elderly hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
    Current medical research and opinion, 1999, Volume: 15, Issue:1

    Topics: Acrylates; Age Factors; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Thiophenes

1999
Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
    Current medical research and opinion, 1999, Volume: 15, Issue:1

    Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Renin; Thiophenes

1999
Effect of eprosartan and enalapril in the treatment of black hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
    Current medical research and opinion, 1999, Volume: 15, Issue:1

    Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes

1999
Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Eprosartan Study Group.
    Clinical therapeutics, 1999, Volume: 21, Issue:3

    Topics: Acrylates; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Placebos; Prospective Studies; Sex Factors; Thiophenes

1999
Pharmacokinetics and protein binding of eprosartan in hemodialysis-dependent patients with end-stage renal disease.
    Pharmacotherapy, 1999, Volume: 19, Issue:5

    Topics: Acrylates; Adult; Antihypertensive Agents; Female; Humans; Imidazoles; Male; Middle Aged; Protein Binding; Renal Dialysis; Renal Insufficiency; Thiophenes

1999
Double-blind comparison of eprosartan and enalapril on cough and blood pressure in unselected hypertensive patients. Eprosartan Study Group.
    Journal of human hypertension, 1999, Volume: 13, Issue:6

    Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cough; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Risk Factors; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Surveys and Questionnaires; Thiophenes; Treatment Outcome

1999
Effect of eprosartan and losartan on uric acid metabolism in patients with essential hypertension.
    Journal of hypertension, 1999, Volume: 17, Issue:7

    Topics: Acrylates; Administration, Oral; Aged; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes; Uric Acid

1999
Efficacy and safety of eprosartan in severe hypertension. Eprosartan Multinational Study Group.
    Blood pressure, 1999, Volume: 8, Issue:2

    Topics: Acrylates; Administration, Oral; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Thiophenes

1999
Improvement of cardiac output in patients with severe heart failure by use of ACE-inhibitors combined with the AT1-antagonist eprosartan.
    European journal of heart failure, 2000, Volume: 2, Issue:2

    Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiac Output; Drug Therapy, Combination; Female; Heart Failure; Humans; Imidazoles; Male; Middle Aged; Pilot Projects; Thiophenes; Ventricular Function, Left

2000
ADEPT: Addition of the AT1 receptor antagonist eprosartan to ACE inhibitor therapy in chronic heart failure trial: hemodynamic and neurohormonal effects.
    American heart journal, 2001, Volume: 141, Issue:5

    Topics: Acrylates; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial Natriuretic Factor; Biomarkers; Catheterization, Swan-Ganz; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Prognosis; Prospective Studies; Radionuclide Ventriculography; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Safety; Thiophenes

2001
Eprosartan provides safe and effective long-term maintenance of blood pressure control in patients with mild to moderate essential hypertension.
    Current medical research and opinion, 2001, Volume: 17, Issue:1

    Topics: Acrylates; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Canada; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome; United States

2001
Comparison of quality of life and cough on eprosartan and enalapril in people with moderate hypertension.
    Journal of human hypertension, 2001, Volume: 15, Issue:12

    Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Double-Blind Method; Drug Administration Schedule; Enalapril; Europe; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Incidence; Male; Middle Aged; North America; Probability; Prospective Studies; Quality of Life; Risk Factors; Severity of Illness Index; South Africa; Thiophenes; Treatment Outcome

2001
Quality of life and cough on antihypertensive treatment: a randomised trial of eprosartan, enalapril and placebo.
    Journal of human hypertension, 2001, Volume: 15, Issue:12

    Topics: Acrylates; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Double-Blind Method; Drug Administration Schedule; Enalapril; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Probability; Quality of Life; Reference Values; Risk Assessment; Severity of Illness Index; Thiophenes; Treatment Outcome

2001
Evaluation of the 24-hour blood pressure effects of eprosartan in patients with systemic hypertension.
    American journal of hypertension, 2001, Volume: 14, Issue:12

    Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes

2001
Eprosartan versus enalapril in elderly patients with hypertension: a double-blind, randomized trial.
    Blood pressure, 2001, Volume: 10, Issue:4

    Topics: Acrylates; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Maximum Tolerated Dose; Therapeutic Equivalency; Thiophenes; Treatment Outcome

2001
Efficacy of eprosartan in combination with HCTZ in patients with essential hypertension.
    Journal of human hypertension, 2002, Volume: 16, Issue:3

    Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes

2002
Effects of enalapril and eprosartan on the renal vascular nitric oxide system in human essential hypertension.
    Kidney international, 2002, Volume: 61, Issue:4

    Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Vessels; Double-Blind Method; Drug Combinations; Enalapril; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Nitric Oxide; omega-N-Methylarginine; Receptor, Angiotensin, Type 1; Renal Circulation; Thiophenes

2002
Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension.
    American journal of hypertension, 2002, Volume: 15, Issue:7 Pt 1

    Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginine; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Thiophenes

2002
AT1 blockers and uric acid metabolism: are there relevant differences?
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2002, Volume: 20, Issue:5

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Double-Blind Method; Humans; Hypertension; Imidazoles; Losartan; Receptor, Angiotensin, Type 1; Thiophenes; Uric Acid

2002
[Metabolic effects of angiotensin-II receptor blockers].
    Kardiologiia, 2002, Volume: 42, Issue:3

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cholesterol; Endothelium, Vascular; Fibrin; Humans; Hypertension; Imidazoles; Male; Receptors, Angiotensin; Thiophenes

2002
Effects of isosorbide mononitrate and AII inhibition on pulse wave reflection in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:2

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Imidazoles; Isosorbide Dinitrate; Male; Middle Aged; Pulse; Thiophenes; Time Factors; Vasodilator Agents

2003
Effects of angiotensin II receptor antagonism on the renal hemodynamic response to cardiovascular stress.
    Kidney international, 2003, Volume: 63, Issue:2

    Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endocrine Glands; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Imidazoles; Lower Body Negative Pressure; Male; Renal Circulation; Severity of Illness Index; Thiophenes

2003
Elevation of sympathetic activity by eprosartan in young male subjects.
    American journal of hypertension, 2003, Volume: 16, Issue:8

    Topics: Acrylates; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Imidazoles; Lower Body Negative Pressure; Male; Muscle, Skeletal; Norepinephrine; Prospective Studies; Stress, Psychological; Sympathetic Nervous System; Thiophenes

2003
AT1 antagonism by eprosartan lowers heart rate variability and baroreflex gain.
    Autonomic neuroscience : basic & clinical, 2003, Aug-29, Volume: 107, Issue:1

    Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Baroreflex; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Imidazoles; Male; Prospective Studies; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thiophenes

2003
[Antihypertensive treatment with eprosartan mesilate of patients in acute and late periods of ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:11

    Topics: Acrylates; Acute Disease; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chi-Square Distribution; Data Interpretation, Statistical; Diastole; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Middle Aged; Quality of Life; Recurrence; Stroke; Systole; Thiophenes; Time Factors

2003
[Effect of eprosartan on microcirculation and blood rheology in patients with hypertensive disease].
    Kardiologiia, 2004, Volume: 44, Issue:2

    Topics: Acrylates; Adult; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Male; Microcirculation; Middle Aged; Rheology; Thiophenes; Treatment Outcome

2004
[Comparison of eprosartan and captopril in left ventricular systolic dysfunction: relation of efficacy to myocardial viability].
    Kardiologiia, 2004, Volume: 44, Issue:1

    Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Systole; Thiophenes; Ventricular Dysfunction, Left

2004
Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertension: data from a 13-week double-blind, placebo-controlled, parallel, multicenter study.
    Journal of human hypertension, 2004, Volume: 18, Issue:9

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome

2004
Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind, placebo-controlled 12-month study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:7

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Glucose; Homeostasis; Humans; Hypertension; Imidazoles; Lipids; Male; Middle Aged; Telmisartan; Thiophenes

2004
A double blind randomized trial to compare the effects of eprosartan and enalapril on blood pressure, platelets, and endothelium function in patients with essential hypertension.
    Japanese heart journal, 2004, Volume: 45, Issue:4

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Endothelium, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Platelet Activation; Prospective Studies; Thiophenes

2004
Effect of eprosartan on cytoplasmic free calcium mobilization, platelet activation, and microparticle formation in hypertension.
    American journal of hypertension, 2004, Volume: 17, Issue:9

    Topics: Acrylates; Adult; Antihypertensive Agents; Blood Pressure; Calcium; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Particle Size; Platelet Activation; Prospective Studies; Stress, Mechanical; Thiophenes

2004
Eprosartan effect on fibrinolytic/hemostatic variables in arterial hypertension: a comparative study to losartan.
    Drugs under experimental and clinical research, 2004, Volume: 30, Issue:3

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Drug Administration Schedule; Female; Fibrinogen; Fibrinolysis; Follow-Up Studies; Hemostasis; Humans; Hypertension; Imidazoles; Lipoproteins; Losartan; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Thiophenes; Thrombomodulin; Time Factors; Tissue Plasminogen Activator

2004
Effect of eprosartan on catecholamines and peripheral haemodynamics in subjects with insulin-induced hypoglycaemia.
    Clinical science (London, England : 1979), 2005, Volume: 108, Issue:2

    Topics: Acrylates; Administration, Oral; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; Epinephrine; Forearm; Heart Rate; Hemodynamics; Humans; Hypoglycemia; Imidazoles; Insulin; Male; Norepinephrine; Thiophenes

2005
Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:11

    Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imidazoles; Kidney Failure, Chronic; Male; Middle Aged; Muscle, Skeletal; Sympathetic Nervous System; Sympatholytics; Thiophenes

2004
Losartan increases bradykinin levels in hypertensive humans.
    Circulation, 2005, Jan-25, Volume: 111, Issue:3

    Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes

2005
Effectiveness and safety of eprosartan on pulse pressure for the treatment of hypertensive patients.
    International journal of clinical practice, 2005, Volume: 59, Issue:4

    Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Pulse; Thiophenes; Treatment Outcome

2005
Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES).
    Stroke, 2005, Volume: 36, Issue:6

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium; Cardiovascular Diseases; Female; Humans; Hypertension; Imidazoles; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nitrendipine; Prospective Studies; Recurrence; Risk Factors; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Stroke; Thiophenes; Time Factors; Treatment Outcome

2005
[Effect of a combination of teveten and prestarium in patients with chronic heart failure].
    Georgian medical news, 2005, Issue:123

    Topics: Acrylates; Antihypertensive Agents; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; Humans; Imidazoles; Male; Perindopril; Thiophenes

2005
Haemodynamic effects of eprosartan and valsartan in hypertensive patients during isometric and mental stress.
    Journal of hypertension, 2005, Volume: 23, Issue:10

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Female; Forearm; Hand Strength; Heart Rate; Humans; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Skin; Stress, Psychological; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome; Valine; Valsartan

2005
Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:4

    Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cross-Over Studies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Norepinephrine; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes

2006
Morbidity and mortality after stroke--eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES).
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Data Interpretation, Statistical; Diuretics; Humans; Imidazoles; Internal Medicine; Ischemic Attack, Transient; Morbidity; Neurology; Nitrendipine; Prospective Studies; Stroke; Thiophenes

2006
MOSES raises questions.
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Acrylates; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Data Interpretation, Statistical; Humans; Imidazoles; Ischemic Attack, Transient; Nitrendipine; Research Design; Risk Factors; Stroke; Thiophenes

2006
Atenolol and eprosartan: differential effects on central blood pressure and aortic pulse wave velocity.
    American journal of hypertension, 2006, Volume: 19, Issue:2

    Topics: Acrylates; Antihypertensive Agents; Aorta, Thoracic; Atenolol; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Pulsatile Flow; Receptor, Angiotensin, Type 1; Thiophenes; Treatment Outcome

2006
Effect of eprosartan on the sympathetic response to cold pressor test in healthy volunteers.
    Autonomic neuroscience : basic & clinical, 2006, Jun-30, Volume: 126-127

    Topics: Acrylates; Administration, Oral; Adolescent; Adult; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cold Temperature; Double-Blind Method; Female; Heart Rate; Humans; Imidazoles; Losartan; Male; Middle Aged; Sympathetic Nervous System; Thiophenes; Time Factors

2006
Eprosartan mesylate effectively reduces systolic and diastolic blood pressure in a Canadian primary care setting.
    The Canadian journal of cardiology, 2004, Volume: 20 Suppl C

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Blood Pressure Determination; Canada; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Probability; Prospective Studies; Reference Values; Severity of Illness Index; Single-Blind Method; Systole; Thiophenes; Treatment Outcome

2004
The angiotensin receptor blocker eprosartan mesylate reduces pulse pressure in isolated systolic hypertension.
    The Canadian journal of cardiology, 2004, Volume: 20 Suppl C

    Topics: Acrylates; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Canada; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Probability; Reference Values; Severity of Illness Index; Systole; Thiophenes; Treatment Outcome

2004
[Effect of eprosartan on psychophysiological functions of drivers with arterial hypertension].
    Kardiologiia, 2006, Volume: 46, Issue:10

    Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension; Imidazoles; Male; Middle Aged; Occupational Diseases; Railroads; Thiophenes

2006
[Role of the renin-angiotensin system on the sympathetic response induced by the cold pressor test in humans].
    Investigacion clinica, 2007, Volume: 48, Issue:2

    Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cold Temperature; Double-Blind Method; Female; Humans; Imidazoles; Losartan; Male; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan

2007
Effects of different AT1-receptor antagonists in the therapy of severe heart failure pretreated with ACE inhibitors.
    Acta cardiologica, 2007, Volume: 62, Issue:4

    Topics: Acrylates; Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biomarkers; Biphenyl Compounds; Blood Pressure; Cardiac Output; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Imidazoles; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Vascular Resistance

2007
[The effectiveness of eprosartan in patients with chronic glomerulonephritis].
    Klinicheskaia meditsina, 2007, Volume: 85, Issue:8

    Topics: Acrylates; Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Female; Glomerulonephritis; Humans; Imidazoles; Male; Thiophenes

2007
Observational Study on Cognitive function And systolic blood pressure Reduction (OSCAR): preliminary analysis of 6-month data from > 10,000 patients and review of the literature.
    Current medical research and opinion, 2007, Volume: 23 Suppl 5

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Animals; Cognition Disorders; Dementia, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Rats; Stroke; Thiophenes

2007
Eprosartan modulates the reflex activation of the sympathetic nervous system in sodium restricted healthy humans.
    British journal of clinical pharmacology, 2008, Volume: 65, Issue:6

    Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diet, Sodium-Restricted; Female; Glomerular Filtration Rate; Humans; Imidazoles; Male; Natriuresis; Sodium, Dietary; Sympathetic Nervous System; Thiophenes

2008
Effects of eprosartan on mitochondrial membrane potential and H2O2 levels in leucocytes in hypertension.
    Journal of human hypertension, 2008, Volume: 22, Issue:7

    Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydrogen Peroxide; Hypertension; Imidazoles; Leukocytes; Male; Membrane Potential, Mitochondrial; Middle Aged; Oxidative Stress; Pilot Projects; Rhodamines; tert-Butylhydroperoxide; Thiophenes

2008
[Effect of antihypertensive drugs of various pharmacological groups on reaction of arterial pressure under conditions of stree testing. Part II. Value of various strategies of potentiation of systemic vasodilatation].
    Kardiologiia, 2008, Volume: 48, Issue:4

    Topics: Acrylates; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exercise Test; Follow-Up Studies; Humans; Hypertension; Imidazoles; Lisinopril; Middle Aged; Propanolamines; Receptor, Angiotensin, Type 1; Thiophenes; Treatment Outcome; Vasodilation

2008
Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: primary results of the Observational Study on Cognitive function And Systolic Blood Pressure Reduction open-label study.
    Journal of hypertension, 2008, Volume: 26, Issue:8

    Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Cognition; Cognition Disorders; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Thiophenes; Treatment Outcome

2008
Superoxide dismutase and catalase anti-oxidant activity in leucocyte lysates from hypertensive patients: effects of eprosartan treatment.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2009, Volume: 10, Issue:1

    Topics: Acrylates; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Cell Extracts; Female; Heart Rate; Humans; Hypertension; Imidazoles; Leukocytes; Male; Middle Aged; Superoxide Dismutase; Thiophenes

2009
Costs of eprosartan versus diuretics for treatment of hypertension in a geriatric population: an observational, open-label, multicentre study.
    Drugs & aging, 2009, Volume: 26, Issue:7

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Costs and Cost Analysis; Diuretics; Female; Geriatrics; Humans; Hypertension; Imidazoles; Male; Thiophenes

2009
Comparative effects of telmisartan and eprosartan on insulin sensitivity in the treatment of overweight hypertensive patients.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, Volume: 41, Issue:12

    Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Glucose; Female; Humans; Hypertension; Imidazoles; Insulin; Male; Middle Aged; Overweight; Telmisartan; Thiophenes

2009
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
    European journal of heart failure, 2010, Volume: 12, Issue:4

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diastole; Female; Glycation End Products, Advanced; Humans; Hypertension; Imidazoles; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Skin; Statistics as Topic; Statistics, Nonparametric; Stroke Volume; Thiophenes; Ventricular Function, Left

2010
Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:1

    Topics: Acrylates; Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diastole; Echocardiography; Female; Heart; Humans; Hypertension; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Stroke Volume; Thiophenes; Treatment Outcome; Ventricular Dysfunction; Ventricular Function; Ventricular Function, Left

2010
Ambulatory monitoring of systolic hypertension in the elderly: Eprosartan/hydrochlorothiazide compared with losartan/hydrochlorothiazide (INSIST trial).
    Advances in therapy, 2010, Volume: 27, Issue:6

    Topics: Acrylates; Aged; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Office Visits; Severity of Illness Index; Statistics, Nonparametric; Systole; Thiophenes; Treatment Outcome

2010
[Adjustment of antihypertensive therapy to a generic eprosartan preparation. Results of a non-interventional study].
    MMW Fortschritte der Medizin, 2010, Oct-14, Volume: 152 Suppl 3

    Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cost Savings; Drug Combinations; Drug Costs; Drug Substitution; Drugs, Generic; Female; Humans; Hydrochlorothiazide; Imidazoles; Male; Middle Aged; National Health Programs; Prospective Studies; Thiophenes

2010
Eprosartan-based hypertension therapy, systolic arterial blood pressure and cognitive function: analysis of Middle East data from the OSCAR study.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Acrylates; Aged; Analysis of Variance; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Arabs; Blood Pressure; Chi-Square Distribution; Cognition; Female; Humans; Hypertension; Imidazoles; Logistic Models; Male; Middle Aged; Middle East; Psychiatric Status Rating Scales; Thiophenes; Time Factors; Treatment Outcome

2011
Pharmacokinetic-pharmacodynamic modeling of the antihypertensive effect of eprosartan in Black and White hypertensive patients.
    Clinical pharmacokinetics, 2013, Volume: 52, Issue:9

    Topics: Acrylates; Adult; Antihypertensive Agents; Black People; Blood Pressure; Cross-Over Studies; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Models, Biological; Thiophenes; White People

2013
[Effect of eprosartan on the hemostatic system in patients with chronic kidney disease associated with hereditary thrombophilia].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:9

    Topics: Acrylates; Adult; Angiotensin II Type 2 Receptor Blockers; Female; Hemostasis; Humans; Imidazoles; Male; Renal Insufficiency, Chronic; Thiophenes; Thrombophilia; Treatment Outcome; Young Adult

2013
Losartan and Eprosartan Induce a Similar Effect on the Acute Rise in Serum Uric Acid Concentration after an Oral Fructose Load in Patients with Metabolic Syndrome.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2021, Volume: 2021

    Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Fructose; Humans; Hypertension; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged; Thiophenes; Uric Acid

2021

Other Studies

137 other study(ies) available for thiophenes and eprosartan

ArticleYear
Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Calcium; Consciousness; Humans; Imidazoles; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Inbred Strains; Thiophenes; Vasoconstriction

1992
Effect of captopril and the nonpeptide angiotensin II antagonists, SK&F 108566 and EXP3174, on renal function in dogs with a renal artery stenosis.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Acrylates; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Imidazoles; Inulin; Kidney; Losartan; Regional Blood Flow; Renal Artery Obstruction; Tetrazoles; Thiophenes

1992
The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Decerebrate State; Enalapril; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Spinal Cord; Tetrazoles; Thiophenes

1992
Characterization of renal angiotensin II receptors using subtype selective antagonists.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Thiophenes

1992
Renin-angiotensin system inhibition reduces glycine-induced glomerular hyperfiltration in conscious rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:1

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Enalapril; Glomerular Filtration Rate; Glycine; Imidazoles; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Renal Circulation; Renin-Angiotensin System; Thiophenes

1992
Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:6

    Topics: Acrylates; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dogs; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Thiophenes

1992
1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Dogs; Imidazoles; In Vitro Techniques; Indicators and Reagents; Kidney; Molecular Conformation; Molecular Structure; Muscle, Smooth, Vascular; Rabbits; Rats; Receptors, Angiotensin; Structure-Activity Relationship; Thiophenes; Vasoconstriction

1991
Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.
    Molecular pharmacology, 1995, Volume: 47, Issue:3

    Topics: Acrylates; Amino Acid Sequence; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Binding Sites; Cells, Cultured; Histidine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis; Rats; Receptors, Angiotensin; Thiophenes

1995
Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Endothelins; Glycopeptides; Imidazoles; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes

1994
Imidazole based non-peptide angiotensin II receptor antagonists. Investigation of the effect of the orientation of the imidazole ring on biological activity.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:11

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Imidazoles; In Vitro Techniques; Losartan; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetrazoles; Thiophenes; Uterine Contraction

1993
Nonpeptide angiotensin II receptor antagonists: potential advantages over ACE inhibitors.
    Proceedings of the Western Pharmacology Society, 1993, Volume: 36

    Topics: Acrylates; Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cough; Dogs; Enalapril; Female; Glomerular Filtration Rate; Imidazoles; Male; Renal Circulation; Thiophenes

1993
Characterization of bovine ovary angiotensin II receptors using subtype-selective antagonists.
    Pharmacology, 1993, Volume: 46, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cattle; Female; Imidazoles; In Vitro Techniques; Oligopeptides; Ovary; Pyridines; Receptors, Angiotensin; Thiophenes

1993
Characterization of [3H]SK&F 108566 as a radioligand for angiotensin type-1 receptor.
    Journal of receptor research, 1993, Volume: 13, Issue:5

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Imidazoles; Male; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes

1993
Potent nonpeptide angiotensin II receptor antagonists. 2. 1-(Carboxybenzyl)imidazole-5-acrylic acids.
    Journal of medicinal chemistry, 1993, Jun-25, Volume: 36, Issue:13

    Topics: Acrylates; Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Rabbits; Rats; Structure-Activity Relationship; Thiophenes

1993
Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Hydrogen-Ion Concentration; Imidazoles; Kidney; Kinetics; Losartan; Male; Microvilli; Naphthalenes; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiophenes; Uric Acid

1996
Short-term exposure to lipopolysaccharide is associated with microvascular contractile dysfunction in vivo.
    Life sciences, 1995, Mar-03, Volume: 56, Issue:15

    Topics: Acrylates; Allopurinol; Animals; Antihypertensive Agents; Arginine; Arterioles; Cheek; Cricetinae; Imidazoles; Indomethacin; Lipopolysaccharides; Male; Mesocricetus; Nitroarginine; Thiophenes; Vasoconstriction; Vasodilation

1995
Renal hemodynamic response to an angiotensin II antagonist, eprosartan, in healthy men.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:2 Pt 1

    Topics: Acrylates; Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Diet, Sodium-Restricted; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Natriuresis; Reference Values; Renal Circulation; Renin; Thiophenes

1997
Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: relationship to differences in prejunctional angiotensin II receptor blockade.
    Pharmacology, 1997, Volume: 55, Issue:5

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan

1997
Pharmacokinetics and protein binding of eprosartan in healthy volunteers and in patients with varying degrees of renal impairment.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:2

    Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Area Under Curve; Humans; Imidazoles; Metabolic Clearance Rate; Middle Aged; Renal Insufficiency; Thiophenes

1998
Determination of SK&F 108566 (Teveten) in human plasma by reversed-phase high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Apr-10, Volume: 707, Issue:1-2

    Topics: Acrylates; Angiotensin II; Calibration; Chromatography, High Pressure Liquid; Humans; Imidazoles; Indicators and Reagents; Quality Control; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Thiophenes

1998
Angiotensin II signaling activities the NO-cGMP pathway in rat proximal tubules.
    Life sciences, 1998, Volume: 63, Issue:4

    Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cyclic GMP; Imidazoles; Kidney Tubules, Proximal; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiophenes

1998
Effect of age and gender on the pharmacokinetics of eprosartan.
    British journal of clinical pharmacology, 1998, Volume: 46, Issue:3

    Topics: Acrylates; Adult; Aged; Aging; Antihypertensive Agents; Area Under Curve; Female; Half-Life; Humans; Imidazoles; Male; Middle Aged; Premenopause; Protein Binding; Sex Factors; Thiophenes

1998
Effects of eprosartan on renal function and cardiac hypertrophy in rats with experimental heart failure.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:4

    Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Heart Failure; Hemodynamics; Imidazoles; Kidney; Male; Rats; Rats, Wistar; Renal Circulation; Sodium; Thiophenes

1998
The evolving role of angiotensin-II receptor blockers in cardiovascular risk reduction. Case study.
    American journal of hypertension, 1998, Volume: 11, Issue:11 Pt 2

    Topics: Acrylates; Adult; Antihypertensive Agents; Black People; Enalapril; Female; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Thiophenes

1998
Review of eprosartan: a new angiotensin II receptor antagonist. Introduction.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Imidazoles; Thiophenes

1999
Review of eprosartan: a new angiotensin II receptor antagonist. Summary.
    Pharmacotherapy, 1999, Volume: 19, Issue:4 Pt 2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Imidazoles; Kidney; Renal Circulation; Thiophenes

1999
ACE inhibition and glucose transport in insulinresistant muscle: roles of bradykinin and nitric oxide.
    The American journal of physiology, 1999, Volume: 277, Issue:1

    Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Female; Glucose; Imidazoles; Insulin Resistance; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker; Thiophenes

1999
Effects of eprosartan on glomerular injury in rats with reduced renal mass.
    Pharmacology, 1999, Volume: 59, Issue:2

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Drug Evaluation, Preclinical; Glomerulosclerosis, Focal Segmental; Imidazoles; Male; Nephrectomy; Proteinuria; Rats; Thiophenes; Vasoconstrictor Agents

1999
Dehydration behavior of eprosartan mesylate dihydrate.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:10

    Topics: Acrylates; Algorithms; Antihypertensive Agents; Calorimetry, Differential Scanning; Crystallization; Desiccation; Drug Stability; Hydrogen Bonding; Imidazoles; Kinetics; Models, Molecular; Particle Size; Tablets; Temperature; Thermogravimetry; Thiophenes; X-Ray Diffraction

1999
A new ACE inhibitor and two new angiotensin receptor blockers for hypertension.
    The Medical letter on drugs and therapeutics, 1999, Nov-05, Volume: 41, Issue:1065

    Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Clinical Trials as Topic; Contraindications; Double-Blind Method; Half-Life; Humans; Hypertension; Imidazoles; Perindopril; Telmisartan; Thiophenes

1999
[Stroke prevention. Is there an added value to RAS inhibition?].
    MMW Fortschritte der Medizin, 2000, Feb-10, Volume: 142, Issue:6

    Topics: Acrylates; Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Rats; Stroke; Thiophenes

2000
Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan

2000
In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists.
    European journal of clinical pharmacology, 2000, Volume: 56, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Irbesartan; Losartan; Microsomes, Liver; Protein Isoforms; Tetrazoles; Thiophenes; Valine; Valsartan

2000
Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:1

    Topics: Acrylates; Adult; Angiotensin II; Diabetic Nephropathies; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperglycemia; Imidazoles; Kidney; Male; Middle Aged; Renal Circulation; Renin; Renin-Angiotensin System; Thiophenes

2000
Gene expression in rats with renal disease treated with the angiotensin II receptor antagonist, eprosartan.
    Physiological genomics, 2000, Nov-09, Volume: 4, Issue:1

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Gene Expression Regulation; Hypertension; Imidazoles; Kidney Diseases; Male; Nephrectomy; Proteinuria; Rats; Rats, Sprague-Dawley; Thiophenes

2000
Direct effects of candesartan and eprosartan on human cloned potassium channels involved in cardiac repolarization.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Acrylates; Action Potentials; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cation Transport Proteins; Cell Line; CHO Cells; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart Conduction System; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Kv1.5 Potassium Channel; Mice; Papillary Muscles; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Shal Potassium Channels; Tetrazoles; Thiophenes; Trans-Activators; Transcriptional Regulator ERG

2001
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
    Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3

    Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2001
[Stress-induced hypertension. The work site--a cardiovascular risk].
    MMW Fortschritte der Medizin, 2001, Mar-15, Volume: 143, Issue:11

    Topics: Acrylates; Antihypertensive Agents; Circadian Rhythm; Humans; Hypertension; Imidazoles; Occupational Diseases; Stress, Psychological; Thiophenes; Workplace

2001
Subcellular localization of angiotensin II in kidney and adrenal.
    Journal of hypertension, 2001, Volume: 19, Issue:3 Pt 2

    Topics: Acrylates; Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Imidazoles; Kidney; Male; Subcellular Fractions; Swine; Thiophenes; Tissue Distribution

2001
Eprosartan reduces cardiac hypertrophy, protects heart and kidney, and prevents early mortality in severely hypertensive stroke-prone rats.
    Cardiovascular research, 2001, Volume: 50, Issue:3

    Topics: Acrylates; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hypertension; Imidazoles; Kidney; Magnetic Resonance Imaging; Male; Myocardium; Natriuresis; Organ Size; Peptide Fragments; Protein Precursors; Proteinuria; Rats; Rats, Inbred SHR; Stroke; Survival Rate; Thiophenes; Ventricular Remodeling

2001
Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:5

    Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Ventricles; Imidazoles; Losartan; Male; Presynaptic Terminals; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Angiotensin; Thiophenes; Vasoconstrictor Agents; Ventricular Function

2001
[Antihypertensive drug. Dual action lowers blood pressure more effectively].
    MMW Fortschritte der Medizin, 2001, May-03, Volume: 143, Issue:18

    Topics: Acrylates; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Thiophenes; Treatment Outcome

2001
Central inhibition of AT1receptors by eprosartan--in vitro autoradiography in the brain.
    Pharmacological research, 2001, Volume: 43, Issue:3

    Topics: Acrylates; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Blood Pressure; Blood-Brain Barrier; Body Weight; Brain; Heart Rate; Imidazoles; Male; Radiography; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Thiophenes

2001
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:6

    Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Biochemistry; Biphenyl Compounds; Drug Design; Imidazoles; Irbesartan; Losartan; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Peptides, Cyclic; Rabbits; Structure-Activity Relationship; Tetrazoles; Thiophenes

2001
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan.
    Journal of hypertension, 2001, Volume: 19, Issue:12

    Topics: Acrylates; Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dihydropyridines; Dose-Response Relationship, Drug; Imidazoles; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Thiophenes; Valine; Valsartan

2001
Intrarenal angiotensin II: interstitial and cellular levels and site of production.
    Kidney international, 2001, Volume: 60, Issue:6

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Imidazoles; Kidney; Swine; Thiophenes; Tissue Distribution

2001
Brain angiotensinergic mediation of enhanced water consumption in lactating rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:3

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Atropine; Brain; Carbachol; Drinking; Female; Imidazoles; Injections, Intraventricular; Lactation; Muscarinic Agonists; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reference Values; Thiophenes

2002
Application of capillary zone electrophoresis to the screening of some angiotensin II receptor antagonists.
    Electrophoresis, 2002, Volume: 23, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Chemical Fractionation; Electrophoresis, Capillary; Imidazoles; Irbesartan; Losartan; Mathematical Computing; Molecular Structure; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2002
Structure elucidation and conformational properties of eprosartan, a non peptide angiotensin II AT1 antagonist.
    Journal of pharmaceutical and biomedical analysis, 2002, Apr-01, Volume: 28, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Imidazoles; Models, Molecular; Molecular Conformation; Monte Carlo Method; Nuclear Magnetic Resonance, Biomolecular; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thermodynamics; Thiophenes

2002
Effects of eprosartan versus hydrochlorothiazide on markers of vascular oxidation and inflammation and blood pressure (renin-angiotensin system antagonists, oxidation, and inflammation).
    The American journal of cardiology, 2002, Mar-15, Volume: 89, Issue:6

    Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Inflammation; Lipoproteins, LDL; Male; Middle Aged; Muscle, Smooth, Vascular; Oxidation-Reduction; Receptors, Angiotensin; Renin-Angiotensin System; Thiophenes; Treatment Outcome; Vascular Cell Adhesion Molecule-1

2002
[Significance of pharmacological blockade of angiotensin II type I receptors for correction of abnormal 24-hour blood pressure profile depending on its variability in patients with arterial hypertension stage II].
    Terapevticheskii arkhiv, 2002, Volume: 74, Issue:2

    Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Thiophenes

2002
The angiotensin type 1 receptor antagonist, eprosartan, attenuates the progression of renal disease in spontaneously hypertensive stroke-prone rats with accelerated hypertension.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:1

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blotting, Western; Body Weight; Dietary Fats; Disease Progression; Extracellular Matrix; Fibrinolysin; Gene Expression Regulation; Heart Rate; Hypertension; Imidazoles; Kidney Diseases; Male; Organ Size; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serine Proteinase Inhibitors; Sodium Chloride, Dietary; Stroke; Thiophenes; Thrombosis

2002
Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery.
    Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:1

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Presynaptic; Tetrazoles; Thiophenes

2002
[Therapy of hypertension. Why the systolic value is decisive].
    MMW Fortschritte der Medizin, 2002, Jun-06, Volume: 144, Issue:23

    Topics: Acrylates; Antihypertensive Agents; Coronary Disease; Enalapril; Humans; Hypertension; Imidazoles; Risk Factors; Stroke; Systole; Thiophenes; Treatment Outcome

2002
Drug points: Dysgeusia and burning mouth syndrome by eprosartan.
    BMJ (Clinical research ed.), 2002, Nov-30, Volume: 325, Issue:7375

    Topics: Acrylates; Antihypertensive Agents; Burning Mouth Syndrome; Dysgeusia; Female; Humans; Imidazoles; Middle Aged; Thiophenes

2002
[Effect of eprosartan on left ventricular diastolic function and cerebral hemodynamics in patients with hypertension].
    Kardiologiia, 2002, Volume: 42, Issue:10

    Topics: Acrylates; Adult; Antihypertensive Agents; Carotid Artery, Internal; Cerebrovascular Circulation; Diastole; Echocardiography; Female; Follow-Up Studies; Homeostasis; Humans; Hypertension; Imidazoles; Male; Middle Aged; Models, Cardiovascular; Thiophenes; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Ventricular Function, Left; Vertebral Artery

2002
Eprosartan for the treatment of hypertension.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:1

    Topics: Acrylates; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Spain; Thiophenes

2003
Effects of the AT1-receptor antagonist eprosartan on the progression of left ventricular dysfunction in dogs with heart failure.
    British journal of pharmacology, 2003, Volume: 138, Issue:2

    Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Disease Progression; Dogs; Heart Failure; Imidazoles; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thiophenes; Ventricular Dysfunction, Left

2003
Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification.
    Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5

    Topics: Acrylates; Algorithms; Angiotensin II; Biphenyl Compounds; Databases, Factual; Imidazoles; Lactones; Losartan; Models, Molecular; Molecular Conformation; Pyridines; Quantitative Structure-Activity Relationship; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfones; Tetrazoles; Thiophenes

2003
Pre- and postsynaptic inhibitory potencies of the angiotensin AT1 receptor antagonists eprosartan and candesartan.
    European journal of pharmacology, 2003, May-23, Volume: 469, Issue:1-3

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Presynaptic Terminals; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Vasoconstriction

2003
Cardiology patient page. Angiotensin receptor blockers.
    Circulation, 2003, Jun-24, Volume: 107, Issue:24

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2003
[When the goal values are more than 20/10 mmHg distant. High blood pressure is to be forced down from two sides immediately].
    MMW Fortschritte der Medizin, 2003, Jul-10, Volume: 145, Issue:27-28

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzothiadiazines; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Sodium Chloride Symporter Inhibitors; Thiophenes; Time Factors

2003
[Dosage equivalents of AT1-receptor antagonists available in Germany].
    Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44

    Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan

2003
Renal damage is not improved by blockade of endothelin receptors in primary renin-dependent hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:12

    Topics: Acrylates; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Blood Pressure; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Glomerulosclerosis, Focal Segmental; Hypertension, Renal; Imidazoles; Kidney; Male; Metalloendopeptidases; Models, Cardiovascular; Nephritis, Interstitial; Organ Size; Osteopontin; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renin; Renin-Angiotensin System; RNA, Messenger; Sialoglycoproteins; Systole; Thiophenes

2003
Impaired neuronal and vascular responses to angiotensin II in a rabbit congestive heart failure model.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:4

    Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Electric Stimulation; Heart Failure; Imidazoles; In Vitro Techniques; Male; Osmolar Concentration; Rabbits; Sympathetic Nervous System; Thiophenes

2003
Re: Heusser et al: elevation of sympathetic activity by eprosartan in young male subjects.
    American journal of hypertension, 2004, Volume: 17, Issue:3

    Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Catecholamines; Heart Rate; Humans; Imidazoles; Male; Muscle, Skeletal; Norepinephrine; Stress, Psychological; Sympathetic Nervous System; Thiophenes

2004
Eprosartan improves cardiac performance, reduces cardiac hypertrophy and mortality and downregulates myocardial monocyte chemoattractant protein-1 and inflammation in hypertensive heart disease.
    Journal of hypertension, 2004, Volume: 22, Issue:3

    Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Chemokine CCL2; Down-Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Immunohistochemistry; Macrophages; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; RNA, Messenger; Thiophenes; Ultrasonography; Vasculitis

2004
Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation.
    Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:3

    Topics: Acrylates; Aging; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Desipramine; Electrophysiology; Imidazoles; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Tetrodotoxin; Thiophenes; Vasoconstriction

2004
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.
    Circulation, 2004, May-04, Volume: 109, Issue:17

    Topics: 3T3 Cells; Acrylates; Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Differentiation; Genes, Reporter; Imidazoles; Insulin Resistance; Irbesartan; Losartan; Luciferases; Mice; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; Telmisartan; Tetrazoles; Thiophenes; Transcription Factors; Transfection

2004
[Anti-hypertensive effect of eprosartan in diabetic patients].
    Anales de medicina interna (Madrid, Spain : 1984), 2004, Volume: 21, Issue:5

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diabetes Complications; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes

2004
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
    Cell stress & chaperones, 2004, Volume: 9, Issue:1

    Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Electrophoretic Mobility Shift Assay; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; Hydralazine; Hypertension; Imidazoles; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; NF-kappa B p50 Subunit; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiophenes; Transcription Factor RelA

2004
[Elevation pressure in morning hours in patients with essential hypertension: effect therapy with eprosartan for leading stress tests].
    Kardiologiia, 2004, Volume: 44, Issue:3

    Topics: Acrylates; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Data Interpretation, Statistical; Exercise Test; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes; Time Factors

2004
Plasma vascular endothelial growth factor, angiopoietin-2, and soluble angiopoietin receptor tie-2 in diabetic retinopathy: effects of laser photocoagulation and angiotensin receptor blockade.
    The British journal of ophthalmology, 2004, Volume: 88, Issue:12

    Topics: Acrylates; Angiopoietin-2; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Cross-Sectional Studies; Diabetic Retinopathy; Female; Humans; Imidazoles; Laser Coagulation; Male; Middle Aged; Receptor, TIE-2; Thiophenes; Vascular Endothelial Growth Factor A

2004
Effect of eprosartan on pulse pressure and blood pressure components in patients with isolated systolic hypertension.
    Blood pressure. Supplement, 2004, Volume: 2

    Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Body Mass Index; Cardiovascular Diseases; Cholesterol, LDL; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Thiophenes; Time Factors

2004
Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:4

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Arteriovenous Fistula; Carboxypeptidases; Cardiomegaly; Disease Models, Animal; Heart Failure; Imidazoles; Male; Mineralocorticoid Receptor Antagonists; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Spironolactone; Thiophenes; Ventricular Remodeling

2005
[Cerebral hemodynamics and endothelium function in patients with cerebrovascular pathology treated by teveten].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Issue:Suppl 13

    Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Brain; Brain Ischemia; Endothelium, Vascular; Female; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Thiophenes; Tomography, X-Ray Computed; Treatment Outcome

2005
Analysis of recent papers in hypertension. An angiotensin receptor blocker is more effective than a calcium channel blocker in secondary stroke prevention.
    Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:8

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Humans; Hypertension; Imidazoles; Nitrendipine; Randomized Controlled Trials as Topic; Stroke; Survival Rate; Thiophenes

2005
Adrenal angiotensin: origin and site of generation.
    American journal of hypertension, 2005, Volume: 18, Issue:8

    Topics: Acrylates; Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Female; Imidazoles; Infusions, Intra-Arterial; Iodine Radioisotopes; Male; Models, Biological; Renin-Angiotensin System; Swine; Thiophenes

2005
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?
    Journal of hypertension, 2005, Volume: 23, Issue:10

    Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome

2005
Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity.
    Diabetes, 2005, Volume: 54, Issue:12

    Topics: 3T3 Cells; Acrylates; Adipocytes; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Differentiation; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; Imidazoles; Irbesartan; Mice; Pioglitazone; PPAR gamma; Protein Conformation; Telmisartan; Tetrazoles; Thiazolidinediones; Thiophenes

2005
Validation of a solid phase extraction-high performance liquid chromatographic method for the determination of eprosartan in human plasma.
    Journal of chromatography. A, 2006, Jun-30, Volume: 1119, Issue:1-2

    Topics: Acrylates; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Stability; Humans; Imidazoles; Reproducibility of Results; Sensitivity and Specificity; Thiophenes

2006
[An AT-II blocker in patients with type II diabetes and arterial hypertension].
    Klinicheskaia meditsina, 2006, Volume: 84, Issue:2

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Diastole; Female; Humans; Hypertension; Imidazoles; Insulin; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Receptor, Angiotensin, Type 1; Thiophenes; Time Factors; Treatment Outcome; Ventricular Function, Left

2006
Does the MOSES study provide sufficient evidence for Eprosartan against Nitrendipine?
    Stroke, 2006, Volume: 37, Issue:6

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Humans; Imidazoles; Nitrendipine; Randomized Controlled Trials as Topic; Stroke; Thiophenes

2006
New tools, old challenges: the emerging role of angiotensin receptor blockers in the treatment of the systolic hypertension epidemic.
    The Canadian journal of cardiology, 2004, Volume: 20 Suppl C

    Topics: Acrylates; Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Canada; Drug Utilization; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prognosis; Risk Assessment; Systole; Thiophenes; Treatment Outcome

2004
The effect of treatment with eprosartan on pulse pressure: factors predicting response.
    The Canadian journal of cardiology, 2004, Volume: 20 Suppl C

    Topics: Acrylates; Administration, Oral; Aged; Aged, 80 and over; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Canada; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Maximum Tolerated Dose; Middle Aged; Predictive Value of Tests; Probability; Prospective Studies; Risk Assessment; Severity of Illness Index; Thiophenes; Treatment Outcome

2004
Preventing cerebrovascular and cardiovascular events after stroke: eprosartan or nitrendipine?
    Nature clinical practice. Neurology, 2006, Volume: 2, Issue:1

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Follow-Up Studies; Humans; Imidazoles; Multicenter Studies as Topic; Nitrendipine; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Thiophenes; Treatment Outcome

2006
[Not all antihypertensive agents protect equally well].
    MMW Fortschritte der Medizin, 2006, Aug-17, Volume: 148, Issue:33-34

    Topics: Acrylates; Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Follow-Up Studies; Humans; Hypertension; Imidazoles; Meta-Analysis as Topic; Nitrendipine; Primary Prevention; Risk Factors; Stroke; Thiophenes; Time Factors

2006
[Stress-associated hypertension in the work place: results of the STARLET project].
    Deutsche medizinische Wochenschrift (1946), 2006, Nov-17, Volume: 131, Issue:46

    Topics: Acrylates; Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Occupational Diseases; Prognosis; Prospective Studies; Stress, Physiological; Thiophenes; Workplace

2006
Rationale, design and methods of the OSCAR study: observational study on cognitive function and systolic blood pressure reduction in hypertensive patients.
    Fundamental & clinical pharmacology, 2007, Volume: 21, Issue:2

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cognition; Cognition Disorders; Female; Humans; Hypertension; Imidazoles; Longitudinal Studies; Male; Middle Aged; Multicenter Studies as Topic; Neuropsychological Tests; Observation; Patient Selection; Receptor, Angiotensin, Type 1; Research Design; Thiophenes

2007
Determination of eprosartan in human plasma and urine by LC/MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Jun-15, Volume: 853, Issue:1-2

    Topics: Acrylates; Chromatography, Liquid; Humans; Imidazoles; Molecular Structure; Reproducibility of Results; Tandem Mass Spectrometry; Thiophenes

2007
Small artery structure adapts to vasodilatation rather than to blood pressure during antihypertensive treatment.
    Journal of hypertension, 2007, Volume: 25, Issue:5

    Topics: Acrylates; Adult; Antihypertensive Agents; Arteries; Blood Pressure; Case-Control Studies; Echocardiography; Female; Humans; Imidazoles; Male; Middle Aged; Thiophenes; Vascular Resistance; Vasodilation; Ventricular Function, Left

2007
Changes in fibrinolytic activity after angiotensin II receptor blockade in therapy-resistant hypertensive patients.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:7

    Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Coagulation; Case-Control Studies; Drug Resistance; Endothelial Cells; Female; Fibrinolysis; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes

2007
Introduction: The pharmacological profile of eprosartan--implications for cerebrovascular and cardiovascular risk reduction.
    Current medical research and opinion, 2007, Volume: 23 Suppl 5

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Cerebrovascular Disorders; Humans; Hypertension; Imidazoles; Middle Aged; Risk; Thiophenes

2007
Selenosartans: novel selenophene analogues of milfasartan and eprosartan.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cricetinae; Female; Imidazoles; Molecular Structure; Organoselenium Compounds; Ovary; Receptor, Angiotensin, Type 1; Stereoisomerism; Structure-Activity Relationship; Sulfur; Thiophenes

2008
Effectiveness of eprosartan in diabetic hypertensive patients.
    European journal of internal medicine, 2008, Volume: 19, Issue:1

    Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Diabetes Complications; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes; Time Factors; Treatment Outcome

2008
Pharmacokinetics and urinary excretion of eprosartan in Chinese healthy volunteers of different gender.
    Die Pharmazie, 2007, Volume: 62, Issue:10

    Topics: Acrylates; Adult; Antihypertensive Agents; Area Under Curve; Electrocardiography; Female; Half-Life; Humans; Imidazoles; Male; Sex Characteristics; Thiophenes

2007
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3

    Topics: Acrylates; Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anilides; Arginine; Benzimidazoles; Benzoates; Cells, Cultured; Cellular Senescence; Down-Regulation; Endothelium, Vascular; Humans; Imidazoles; Nitric Oxide; Oxidative Stress; PPAR gamma; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Thiophenes; Up-Regulation

2008
Separation and quantitation of several angiotensin II receptor antagonist drugs in human urine by a SPE-HPLC-DAD method.
    Journal of separation science, 2008, Volume: 31, Issue:4

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Chromatography, High Pressure Liquid; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Solid Phase Extraction; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2008
[Effect of eprosartan on thrombocytes aggregative capacity in patients with arterial hypertension and metabolic syndrome].
    Klinicheskaia meditsina, 2008, Volume: 86, Issue:4

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Metabolic Syndrome; Middle Aged; Platelet Aggregation; Thiophenes; Treatment Outcome

2008
Spectral and polarographic determination of eprosartan. Kinetic studies of the oxidation of eprosartan using a platinum electrode.
    Die Pharmazie, 2008, Volume: 63, Issue:6

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Cerium; Electrodes; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Oxidation-Reduction; Platinum; Polarography; Potassium Chloride; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Temperature; Thermodynamics; Thiophenes

2008
Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growt
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Acrylates; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalapril; Humans; Imidazoles; Indazoles; Lisinopril; Male; Mice; Mice, SCID; Neoplasms; Nifedipine; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Ramipril; Rats; Rats, Sprague-Dawley; Telmisartan; Thiophenes; Xenograft Model Antitumor Assays

2009
Hemodynamic and cardiac effects of chronic eprosartan and moxonidine therapy in stroke-prone spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:5

    Topics: Acrylates; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Hypertension; Imidazoles; Male; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Inbred SHR; Stroke; Thiophenes; Ventricular Function, Left

2009
Angiotensin receptor blockers and secondary stroke prevention: the MOSES study.
    Expert review of cardiovascular therapy, 2009, Volume: 7, Issue:5

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Ischemic Attack, Transient; Male; Nitrendipine; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thiophenes

2009
Cost-utility analysis of eprosartan compared to enalapril in primary prevention and nitrendipine in secondary prevention in Europe--the HEALTH model.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2009, Volume: 12, Issue:6

    Topics: Acrylates; Antihypertensive Agents; Cardiovascular Diseases; Cost-Benefit Analysis; Enalapril; Europe; Geography; Humans; Hypertension; Imidazoles; Male; Meta-Analysis as Topic; Middle Aged; Monte Carlo Method; Nitrendipine; Primary Prevention; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Stroke; Thiophenes

2009
[The use of melaxen in combined therapy of arterial hypertension in subjects occupied in assembly line production].
    Klinicheskaia meditsina, 2009, Volume: 87, Issue:6

    Topics: Acrylates; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Central Nervous System Depressants; Circadian Rhythm; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Imidazoles; Industry; Melatonin; Middle Aged; Occupational Diseases; Occupational Exposure; Thiophenes; Treatment Outcome

2009
Characterization of a novel impurity in bulk drug eprosartan by ESI/MS(n) and NMR.
    Journal of pharmaceutical and biomedical analysis, 2010, Feb-05, Volume: 51, Issue:3

    Topics: Acrylates; Drug Contamination; Imidazoles; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Thiophenes

2010
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.
    Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:2-3

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes

2010
Design and methodology of POWER, an open-label observation of the effect of primary care interventions on total cardiovascular risk in patients with hypertension.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:2

    Topics: Acrylates; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Canada; Cardiovascular Diseases; Humans; Hypertension; Imidazoles; Primary Health Care; Product Surveillance, Postmarketing; Research Design; Risk Factors; Thiophenes

2013
Blood pressure responses to hypertension treatment and trends in cognitive function in patients with initially difficult-to-treat hypertension: a retrospective subgroup analysis of the Observational Study on Cognitive Function and SBP Reduction (OSCAR) st
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:2

    Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cognition; Female; Humans; Hypertension; Imidazoles; Intention to Treat Analysis; Male; Middle Aged; Retrospective Studies; Thiophenes

2012
Determination of eprosartan mesylate and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.
    Journal of chromatographic science, 2012, Volume: 50, Issue:8

    Topics: Acrylates; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Hydrochlorothiazide; Imidazoles; Tablets; Thiophenes

2012
[The use of melatonin for correction of sleep disturbances in assembly-line shift workers with arterial hypertension].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:3

    Topics: Acrylates; Adult; Antihypertensive Agents; Circadian Clocks; Female; Humans; Hypertension; Imidazoles; Male; Melatonin; Middle Aged; Sleep Disorders, Circadian Rhythm; Thiophenes; Work Schedule Tolerance

2012
Interstitial pneumonitis secondary to eprosartan.
    Archivos de bronconeumologia, 2012, Volume: 48, Issue:12

    Topics: Acrylates; Antihypertensive Agents; Humans; Imidazoles; Lung Diseases, Interstitial; Male; Middle Aged; Thiophenes

2012
Effect of eprosartan-based therapy on systolic blood pressure and total cardiovascular risk in a large international population: preliminary report of the observational POWER study.
    Vascular health and risk management, 2012, Volume: 8

    Topics: Acrylates; Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 2 Receptor Blockers; Blood Pressure; Cardiovascular Diseases; Chi-Square Distribution; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Product Surveillance, Postmarketing; Risk Factors; Statistics, Nonparametric; Systole; Thiophenes; Treatment Outcome

2012
Association between eprosartan-based hypertension therapy and improvement in cognitive function score: long-term follow-up from the OSCAR observational study.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:2

    Topics: Acrylates; Aged; Aged, 80 and over; Blood Pressure; Cognition; Demography; Diastole; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Systole; Thiophenes

2015
Effect of eprosartan-based antihypertensive therapy on coronary heart disease risk assessed by Framingham methodology in Canadian patients: results of the POWER survey.
    Vascular health and risk management, 2014, Volume: 10

    Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Canada; Coronary Disease; Drug Therapy, Combination; Female; Health Care Surveys; Humans; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Risk Assessment; Risk Factors; Thiophenes; Time Factors; Treatment Outcome

2014
Eprosartan improves cardiac function in swine working heart model of ischemia-reperfusion injury.
    Medical science monitor basic research, 2014, Apr-25, Volume: 20

    Topics: Acrylates; Animals; Blood Pressure; Disease Models, Animal; Heart Function Tests; Heart Ventricles; Imidazoles; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Swine; Thiophenes

2014
Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment.
    Environmental science and pollution research international, 2014, Volume: 21, Issue:18

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biodegradation, Environmental; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Germany; Imidazoles; Irbesartan; Mass Spectrometry; Molecular Structure; Rivers; Tetrazoles; Thiophenes; Valine; Valsartan; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2014
OATP and MRP2-mediated hepatic uptake and biliary excretion of eprosartan in rat and human.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:2

    Topics: Acrylates; Animals; Bile; Biological Transport; Dogs; HEK293 Cells; Hepatocytes; Humans; Imidazoles; In Vitro Techniques; Liver; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Rats; Rats, Wistar; Thiophenes

2014
Quality by design: a systematic and rapid liquid chromatography and mass spectrometry method for eprosartan mesylate and its related impurities using a superficially porous particle column.
    Journal of separation science, 2014, Volume: 37, Issue:16

    Topics: Acetonitriles; Acrylates; Ammonium Compounds; Chemistry, Pharmaceutical; Chromatography, Liquid; Chromatography, Reverse-Phase; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Imidazoles; Mass Spectrometry; Porosity; Reproducibility of Results; Software; Temperature; Thiophenes

2014
Versatile reticular polyethylenimine derivative-mediated targeted drug and gene codelivery for tumor therapy.
    Molecular pharmaceutics, 2014, Oct-06, Volume: 11, Issue:10

    Topics: Acrylates; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Atomic Force; Microvessels; Neovascularization, Pathologic; Polyethyleneimine; Thiophenes

2014
Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:2

    Topics: Acrylates; Angiotensin II; Animals; Anthracenes; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Imidazoles; Macrophages; Male; MAP Kinase Signaling System; Mice; Prostaglandin D2; Thiophenes; Up-Regulation

2015
Ameliorative effect of eprosartan on high-fat diet/streptozotocin-induced early diabetic nephropathy in rats.
    European journal of pharmacology, 2015, Mar-05, Volume: 750

    Topics: Acrylates; Angiotensin II; Animals; Blood Glucose; Catalase; Cholesterol; Collagen Type IV; Diabetic Nephropathies; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Glutathione; Imidazoles; Kidney; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; RNA, Messenger; Streptozocin; Thiophenes; Transforming Growth Factor beta1; Triglycerides

2015
Celiac disease-like enteropathy due to antihypertensive therapy with the angiotensin-II receptor type 1 inhibitor eprosartan.
    Ceskoslovenska patologie, 2015, Volume: 51, Issue:2

    Topics: Acrylates; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Celiac Disease; Female; Humans; Hypertension; Imidazoles; Thiophenes

2015
A self-assembled system for tumor-targeted co-delivery of drug and gene.
    Materials science & engineering. C, Materials for biological applications, 2015, Nov-01, Volume: 56

    Topics: Acrylates; Chondroitin Sulfates; Drug Delivery Systems; Endocytosis; Gene Transfer Techniques; Hep G2 Cells; Humans; Imidazoles; Neoplasms; Plasmids; Polyethyleneimine; Thiophenes

2015
Influence of initial angiotensin receptor blockers on treatment persistence in uncomplicated hypertension: A nation-wide population-based study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2016, Volume: 38, Issue:3

    Topics: Acrylates; Adult; Aged; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cohort Studies; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Medication Adherence; Middle Aged; Outcome Assessment, Health Care; Republic of Korea; Retrospective Studies; Risk Factors; Tetrazoles; Thiophenes; Valsartan

2016
Acute eprosartan-induced intrarenal vasodilation in hypertensive humans is not influenced by dietary sodium intake or angiotensin II co-infusion.
    Journal of hypertension, 2016, Volume: 34, Issue:8

    Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Artery; Renal Circulation; Renin-Angiotensin System; Sodium; Sodium, Dietary; Thiophenes; Vasodilation

2016
Formulation and statistical optimization of self-microemulsifying drug delivery system of eprosartan mesylate for improvement of oral bioavailability.
    Drug delivery and translational research, 2016, Volume: 6, Issue:5

    Topics: Acrylates; Administration, Oral; Animals; Biological Availability; Drug Delivery Systems; Drug Liberation; Emulsions; Excipients; Imidazoles; Male; Particle Size; Rats; Solubility; Thiophenes

2016
[Psychological Characteristics of Patients With Stress-induced Arterial Hypertension: a Violation of the Regulation of Emotions as a Central Link of Pathogenesis].
    Kardiologiia, 2016, Volume: 56, Issue:9

    Topics: Acrylates; Adult; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Determination; Emotions; Female; Humans; Hypertension; Imidazoles; Indapamide; Male; Middle Aged; Random Allocation; Stress, Psychological; Thiophenes; Treatment Outcome

2016
The non-biphenyl-tetrazole angiotensin AT
    British journal of pharmacology, 2018, Volume: 175, Issue:12

    Topics: Acrylates; Animals; Catalytic Domain; Dose-Response Relationship, Drug; Humans; Imidazoles; Ligands; Models, Molecular; Molecular Structure; Receptor, Angiotensin, Type 1; Structure-Activity Relationship; Thiophenes

2018
Risk assessment and QbD based optimization of an Eprosartan mesylate nanosuspension: In-vitro characterization, PAMPA and in-vivo assessment.
    International journal of pharmaceutics, 2019, Aug-15, Volume: 567

    Topics: Acrylates; Animals; Antihypertensive Agents; Drug Liberation; Imidazoles; Intestinal Mucosa; Male; Membranes, Artificial; Nanoparticles; Permeability; Rats, Wistar; Risk Assessment; Suspensions; Thiophenes

2019
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
    Journal of separation science, 2020, Volume: 43, Issue:8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan

2020
Molecular and Genetic Bases of Inhibition of Tick-Borne Encephalitis Virus Replication by Eprosartan and Ribavirin.
    Bulletin of experimental biology and medicine, 2020, Volume: 170, Issue:1

    Topics: Acrylates; Animals; Antiviral Agents; Cell Line; Cell Survival; Encephalitis Viruses, Tick-Borne; Epithelial Cells; Imidazoles; Kidney; Microbial Sensitivity Tests; Ribavirin; Swine; Thiophenes; Virus Replication

2020
Formulation and design optimization of nano-transferosomes using pioglitazone and eprosartan mesylate for concomitant therapy against diabetes and hypertension.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2021, Jul-01, Volume: 162

    Topics: Acrylates; Animals; Diabetes Mellitus, Type 2; Drug Carriers; Drug Delivery Systems; Humans; Hypertension; Imidazoles; Liposomes; Mesylates; Particle Size; Pioglitazone; Rats; Rats, Wistar; Thiophenes

2021
Eprosartan: A closer insight into its neuroprotective activity in rats with focal cerebral ischemia-reperfusion injury.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:7

    Topics: Acrylates; Animals; Brain; Cerebrovascular Disorders; Imidazoles; Male; Nerve Tissue Proteins; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Thiophenes

2021
Protective and therapeutic role of mango pulp and eprosartan drug and their anti-synergistic effects against thioacetamide-induced hepatotoxicity in male rats.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:34

    Topics: Acrylates; Animals; Antioxidants; Becaplermin; Chemical and Drug Induced Liver Injury; Fibrosis; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Imidazoles; Inflammation; Liver; Male; Mangifera; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Superoxide Dismutase; Thioacetamide; Thiophenes; Tumor Necrosis Factor-alpha

2022
Formulation and characterization of eprosartan mesylate and β-cyclodextrin inclusion complex prepared by microwave technology.
    Drug delivery, 2022, Volume: 29, Issue:1

    Topics: Acrylates; beta-Cyclodextrins; Calorimetry, Differential Scanning; Imidazoles; Mesylates; Microwaves; Solubility; Spectroscopy, Fourier Transform Infrared; Technology; Thiophenes; X-Ray Diffraction

2022
ATR1 Angiotensin II Receptor Reduces Hemoglobin S Polymerization, Phosphatidylserine Exposure, and Increases Deformability of Sickle Cell Disease Erythrocytes.
    Cell biochemistry and biophysics, 2022, Volume: 80, Issue:4

    Topics: Acrylates; Anemia, Sickle Cell; Angiotensin II; Annexin A5; Erythrocytes; Hemoglobin, Sickle; Humans; Imidazoles; Losartan; Phosphatidylserines; Polymerization; Receptor, Angiotensin, Type 1; Thiophenes

2022