thiophenes has been researched along with eprosartan in 257 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 62 (24.12) | 18.2507 |
2000's | 154 (59.92) | 29.6817 |
2010's | 33 (12.84) | 24.3611 |
2020's | 8 (3.11) | 2.80 |
Authors | Studies |
---|---|
Benfield, P; Chiu, AT; Herblin, WF; Smith, RD; Timmermans, PB; Wong, PC | 1 |
Aiyar, N; Edwards, RM; Ezekiel, M; Griffin, E; Keenan, RM; Ohlstein, EH; Ruffolo, RR; Weidley, EF; Weinstock, J | 1 |
Brooks, DP; DePalma, PD; Ruffolo, RR | 1 |
Brooks, DP; Edwards, RM; Gellai, M; Jugus, J; Ohlstein, EH; Ruffolo, RR; Sulpizio, A; Vickery, L; Weinstock, J | 1 |
Aiyar, N; Edwards, RM; Hill, DT; Keenan, RM; Stack, EJ; Weidley, EF; Weinstock, J | 1 |
Brooks, DP; Wang, YX | 1 |
Brooks, DP; Edwards, RM; Fredrickson, TA; Gellai, M; Ruffolo, RR; Weinstock, J | 1 |
Finkelstein, JA; Franz, RG; Gaitanopoulos, DE; Girard, GR; Gleason, JG; Hempel, J; Hill, DT; Keenan, RM; Samanen, J; Weinstock, J | 1 |
Hjorth, SA; Schambye, HT; Schwartz, TW; Weinstock, J | 1 |
Bauer, JH; Reams, GP | 1 |
Arleth, AJ; Ohlstein, EH; Storer, BL; Sung, CP | 1 |
Ganter, RC; Hondrelis, J; Matsoukas, J; Moore, DM; Moore, GJ; Smith, JR; Wahhab, A | 1 |
Brooks, DP; DePalma, PD; Fredrickson, TA; Ruffolo, RR; Spielman, WS | 1 |
Aiyar, N; Edwards, R; Griffin, E; Nambi, P; Samanen, J; Weinstock, J | 1 |
Aiyar, N; Bergsma, DJ; Edwards, R; Griffin, E; Heys, R; Shu, A; Weinstock, J | 1 |
Finkelstein, JA; Franz, RG; Gaitanopoulos, DE; Girard, GR; Hill, DT; Keenan, RM; Morgan, TM; Peishoff, CE; Samanen, JM; Weinstock, J | 1 |
Edwards, RM; Stack, EJ; Trizna, W; Weinstock, J | 1 |
Gao, XP; Olopade, CO; Rubinstein, I; Suzuki, H | 1 |
Boike, SC; DeCherney, GS; Freed, MI; Ilson, BE; Jones, BA; Jorkasky, DK; Martin, DE | 1 |
Boike, SC; Citerone, D; Ilson, B; Jorkasky, DK; Martin, DE; Tenero, D; Tompson, D | 1 |
De'Oliveira, JM; Fisher, ND; Hollenberg, NK; Price, DA | 1 |
Blum, RA; Boike, SC; Etheredge, R; Ilson, B; Jorkasky, DK; Kazierad, DJ; Martin, DE; Tenero, DM | 1 |
Brooks, DP; Feuerstein, GZ; Ohlstein, EH; Ruffolo, RR | 1 |
Boike, SC; Boyle, DA; Carr, AM; Ilson, BE; Jorkasky, DK; Lundberg, DE; Martin, DE; Tenero, DM | 1 |
Boike, SC; Chapelsky, MC; Ilson, B; Jorkasky, DK; Martin, DE; Tenero, D; Zariffa, N | 1 |
Boike, SC; Freed, MI; Ilson, BE; Jorkasky, DK; Martin, DE; Zariffa, N | 1 |
Balfour, JA; McClellan, KJ | 1 |
Boike, SC; Chapelsky, MC; Etheredge, R; Ilson, BE; Jorkasky, DK; Martin, DE; Tenero, DM | 1 |
Boike, SC; Ilson, BE; Jorkasky, DK; Martin, DE | 1 |
Cyronak, MJ; Knox, S; Lundberg, DE; Person, CR | 1 |
Mayeux, PR; Zhang, C | 1 |
Boike, S; Forrest, A; Ilson, B; Jorkasky, DK; Kazierad, DJ; Martin, DE; Zariffa, N | 1 |
Boike, S; Boyle, D; Ilson, B; Jorkasky, D; Jushchyshyn, J; Lundberg, D; Martin, D; Tenero, D; Zariffa, N | 1 |
Boike, SC; Ilson, B; Jorkasky, DK; Martin, DE; Miller, AK; Tenero, DM; Zariffa, N | 1 |
Abassi, Z; Brodsky, S; Feuerstein, GZ; Gurbanov, K; Hoffman, A; Ruffolo, RR; Winaver, J | 1 |
Oparil, S | 1 |
Chung, O; Csikós, T; Unger, T | 1 |
Hedner, T; Himmelmann, A | 1 |
Hollenberg, NK | 2 |
Bottorff, MB; Tenero, DM | 1 |
Blum, RA; Kazierad, DJ; Tenero, DM | 1 |
Hollenberg, NK; Sica, DA | 1 |
Weber, M | 1 |
Gavras, H; Gavras, I | 2 |
Sica, DA | 2 |
Diamond, JA; Gharavi, A; Henzlova, MJ; Machac, J; Phillips, RA; Roychoudhury, D; Travis, A | 1 |
Argenziano, L; Trimarco, B | 1 |
Levine, B | 2 |
Gradman, AH; Gray, J; Maggiacomo, F; Punzi, H; White, WB | 1 |
Ilson, BE; Jorkasky, DK; Kovacs, SJ; Martin, DE; Tenero, DM | 1 |
Elliott, WJ | 1 |
Dietze, GJ; Henriksen, EJ; Jacob, S; Kinnick, TR; Schmit, MB; Youngblood, EB | 1 |
Buño, A; Dal-Ré, R; Mateos, F; Ortega, R; Puig, JG; Rodriguez, F | 1 |
Brooks, DP; Gandhi, M; Meyer, TW | 1 |
Sega, R | 1 |
Hedner, T | 2 |
Brooks, DP; Ruffolo, RR | 1 |
Shusterman, NH | 1 |
Brooks, DP; Ohlstein, EH; Ruffolo, RR | 1 |
Duddu, SP; Grant, DJ; Sheng, J; Venkatesh, GM | 1 |
Gremmler, B; Kunert, M; Schleiting, H; Ulbricht, LJ | 1 |
DelGrande, D; Shetty, SS | 1 |
Kiukaanniemi, K; Pelkonen, O; Taavitsainen, P | 1 |
Grossman, E; Messerli, FH; Neutel, JM | 1 |
Hollenberg, NK; Laffel, LM; Lansang, MC; Osei, SY; Price, DA | 1 |
Foster, RH; Plosker, GL | 1 |
Brooks, DP; Contino, LC; Grygielko, E; Laping, NJ; Olson, BA; Wong, VY | 1 |
Benkel, M; Maisch, B; Rupp, H | 1 |
Chikhladze, NM | 1 |
Caballero, R; Delpón, E; González, T; Longobardo, M; Tamargo, J; Valenzuela, C | 1 |
Vidt, DG | 1 |
Ramahi, TM | 1 |
Dargie, HJ; Farmer, R; McDonagh, TA; McMurray, JJ; Morton, JJ; Murdoch, DR | 1 |
Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP; van Meegen, JR; Verdouw, PD | 1 |
Barone, FC; Brooks, DP; Campbell, WG; Chandra, S; Coatney, RW; Contino, LC; Nelson, AH; Ohlstein, EH; Sarkar, SK; Willette, RN | 1 |
Guimarães, S; Loio, A; Moura, D; Pinheiro, H; Tavares, P | 1 |
Bahner, U; Elsner, D; Jandeleit-Dahm, K; Kirst, I; Muders, F; Palkovits, M | 1 |
Giatas, N; Golic Grdadolnik, S; Iliodromitis, EK; Keivish, T; Kremastinos, DT; Matsoukas, J; Mavromoustakos, T; Mutule, I; Polevaya, L; Roumelioti, P; Vlahakos, DV; Zoumboulakis, P | 1 |
Magometschnigg, D | 1 |
Gavras, HP | 1 |
Krum, H | 1 |
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA | 1 |
Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP; Verdouw, PD | 1 |
Breeze, E; Donoghue, MD; Fletcher, AE; Rake, EC | 1 |
Breeze, E; Fletcher, AE; Rake, EC | 1 |
Anwar, YA; Mansoor, GA; Sica, DA; White, WB | 1 |
Jäger, B; Prichard, B; Ruilope, L | 1 |
McInnes, GT | 1 |
Grove, KL; Smith, MS; Speth, RC | 1 |
Akesolo, U; Alonso, RM; González, L; Jiménez, RM | 1 |
Grdadolnik, SG; Matsoukas, J; Mavromoustakos, T; Zoumpoulakis, P | 1 |
Jäger, B; Sachse, A; Verboom, CN | 1 |
Khan, BV; Khan, QA; Lauten, WB; Navalkar, S; Parthasarathy, S; Rahman, ST | 1 |
Al'-Iazidi, MA; Barsukov, AV; Konev, AV; Kulikov, AN; Shustov, SB | 1 |
Abrahamsen, CT; Barone, FC; Brooks, DP; Campbell, WG; Contino, LC; Edwards, RM; Grygielko, ET; Laping, NJ; Nelson, AH; Pullen, MA | 1 |
Delles, C; Fleischmann, I; Jacobi, J; John, S; Schmieder, RE | 1 |
Balt, JC; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA | 2 |
Rapi, J | 1 |
Böhm, M; Sachse, A | 1 |
Delles, C; Gekle, M; John, S; Schmieder, RE; Schneider, MP | 1 |
Puig, JG; Ruilope, LM; Torres, R | 1 |
Gurevich, MA | 1 |
Castells, X; Cereza, G; Laporte, JR; Pedrós, C; Rodoreda, I | 1 |
Belavina, NI; Griabina, NA; Koren'kov, VV; Markova, LI; Radzevich, AE; Zharova, OIu | 1 |
Nebieridze, DV; Oganov, RG | 1 |
Jäger, B; Ruilope, L | 1 |
Mancini, GB | 1 |
Anagnostopoulos, PV; Chaudhry, PA; Goldstein, S; Gupta, RC; Mishima, T; Nass, O; Rostogi, S; Sabbah, HN; Sharov, VG; Suzuki, G; Tanhehco, EJ; Todor, A | 1 |
Barin, ES; Gilfillan, KL; Stokes, GS | 1 |
Krovat, EM; Langer, T | 1 |
Frank, H; Heusser, K; Schmieder, RE; Schobel, HP; Vitkowsky, J | 1 |
Bernardino, JI; Bueso, TS; Jiménez, RT; López, MA; Puig, JG | 1 |
Schieffer, B; Schmidt, B | 1 |
Terra, SG | 1 |
Heusser, K; Raasch, W; Schmieder, RE; Schobel, HP; Vitkovsky, J | 1 |
Heusser, K; Schmieder, RE; Schobel, HP; Vitkovsky, J | 1 |
Jermendy, G; Matos, L; Winkler, G | 1 |
Sidorenko, GI | 1 |
Dominiak, P; Häuser, W | 1 |
Kossmehl, P; Kreutz, R; Neumayer, HH; Paul, M; Rothermund, L | 1 |
Boĭko, AN; Gusev, EI; Makarov, AN; Martynov, MIu; Petukhov, EB | 1 |
Balt, JC; Belterman, CN; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA | 1 |
Rupp, H | 2 |
Koren'kov, VV; Markova, LI; Radzevich, AE; Shakhova, NI | 1 |
Metlitskaia, EV; Petrik, ES; Shalaev, SV; Shanaurina, NV; Teffenberg, DV; Volkova, SIu | 1 |
Ivanova, NA; Preobrazhenskiĭ, DV; Sidorenko, BA; Soplevenko, AV; Stetsenko, TM | 1 |
Punzi, CF; Punzi, HA | 1 |
Anderson, K; Angermann, CE; Barone, FC; Behr, TM; Berova, M; Coatney, RW; Sackner-Bernstein, JD; Willette, RN | 1 |
Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA | 1 |
Clasen, R; Janke, J; Kintscher, U; Schupp, M; Unger, T | 1 |
Alonso, FJ; Blanco, J; Gamero, MJ; Jiménez Pérez, JL; Masot, J; Matilla, C; Nieto, J; Robles, NR; Romero, F; Velasco, J | 1 |
Chen, Y; Currie, RW; Ross, BM | 1 |
Ciccarelli, L; Derosa, G; Fogari, R; Mugellini, A; Ragonesi, PD | 1 |
Charng, MJ; Ding, PY; Leu, HB | 1 |
Aznar, J; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Munoz, A | 1 |
Hatzizacharias, A; Krespi, P; Makris, TK; Papadopoulos, DP; Stavroulakis, G; Tsoukala, C; Votteas, VE; Zilidis, A | 1 |
Christensen, M; Ibsen, H; Worck, R | 1 |
Lapina, EIa; Makarova, SV; Praskurnichiĭ, EA; Samartsev, GA; Shevchenko, OP | 1 |
Blankestijn, PJ; Koomans, HA; Ligtenberg, G; Neumann, J; Oey, L | 1 |
Blann, AD; Caine, GJ; Chatterjee, S; Gibson, J; Hope-Ross, M; Lip, GY; Lip, PL | 1 |
Arcos, E; de la Sierra, A; Lopez, JS; Munoz, A; Relats, J | 2 |
Campbell, DJ; Esler, MD; Krum, H | 1 |
Alamo, C; López-Muñoz, F; Martín-Agueda, B; Robles, NR | 2 |
Berger, J; Diener, HC; Dominiak, P; Hammersen, F; Kulschewski, A; Lüders, S; Plate, K; Schrader, J; Zidek, W | 1 |
Abassi, Z; Abbasi, A; Golomb, E; Hochberg, I; Hoffman, A; Karram, T; Keidar, S; Winaver, J | 1 |
foniakin, AV; Geraskina, LA; Konradi, VV; Sharypova, TN; Suslina, ZA | 1 |
Abashidze, TB; Gorgoshidze, ML | 1 |
Basile, J; Bloch, MJ | 1 |
Chai, W; Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP | 1 |
Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K | 1 |
Arosio, E; De Marchi, S; Lechi, A; Prior, M; Rigoni, A | 1 |
Robins, GW; Scott, LJ | 1 |
Campbell, DJ; Esler, M; Krum, H; Lambert, E; Windebank, E | 1 |
Clemenz, M; Gineste, R; Helleboid, S; Hennuyer, N; Janke, J; Kintscher, U; Ruiz, P; Schupp, M; Staels, B; Unger, T; Witt, H | 1 |
Boulanger, JM; Hill, MD | 1 |
Strauss, MH; Verma, S | 1 |
Brown, MJ; Cockcroft, JR; Dhakam, Z; McEniery, CM; Wilkinson, IB | 1 |
Alonso, RM; Ferreirós, N; Iriarte, G; Jiménez, RM; Ortíz, E | 2 |
Ametov, AS; Demidova, TIu; Kosykh, SA | 1 |
Cierco, M; del Rosario Garrido, M; Gutierrez, A; Israel, A; Zavala, LE | 1 |
Boysen, G; Hornnes, N; Larsen, K | 1 |
Feldman, RD | 1 |
Conter, HS; McKay, DW; Reiz, RJ | 1 |
Chilvers, M; Reiz, RJ; Teitelbaum, I | 1 |
Johnston, SC | 1 |
Frerichs, A; Frieg, R; Hahnheiser, D; Hammersen, F; Kulschewski, A; Lüders, S; Reich, G; Schnieders, M; Schrader, J; Schrandt, G | 1 |
At'kova, EO; Gutnikova, OV; Tsfasman, AZ | 1 |
de la Sierra, A | 1 |
Hanon, O; Negre-Pages, L; Pathak, A; Sevenier, F | 1 |
Chen, WL; Chu, NN; Li, XN; Liu, GY; Xu, HR; Yu, C | 2 |
Buus, NH; Christensen, KL; Larsen, ML; Mathiassen, ON; Mulvany, MJ | 1 |
de Leeuw, PW; Dielis, AW; Hamulyák, K; Houben, AJ; Kroon, AA; Smid, M; Spronk, HM; Ten Cate, H | 1 |
Cierco, M; Garrido, MR; Gutiérrez, A; Israel, A; Zavala, LE | 1 |
Aulakh, GK; Singh, M; Sodhi, RK | 1 |
Gremmler, B; Kisters, K; Kunert, M; Schleiting, H; Ulbricht, LJ | 1 |
Kaliuzhin, VV; Kaliuzhina, EV; Kolesnikov, RN; Konaplev, DI; Solovtsev, MA; Surkova, LG; Zibnitskaia, LI | 1 |
Ram, CV; Rudmann, MA | 1 |
de la Sierra, A; Ram, CV | 1 |
Ram, CV | 1 |
Shlyakhto, E | 1 |
Angus, JA; Grange, RL; North, AJ; Schiesser, CH; Ziogas, J | 1 |
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M | 1 |
Bech, JN; Lauridsen, TG; Pedersen, EB; Vase, H | 1 |
Beltrán, B; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Muñoz, A; Ruiz-Aja, S | 1 |
Makarova, SV; Praskurnichiĭ, EA; Savel'eva, SA; Shevchenko, OP; Zhukova, VA | 1 |
Kumova, TA; Medvedev, IN; Simonenko, VB | 1 |
El-Yazbi, FA; Hammud, HH; Sonji, GM; Sonji, NM | 1 |
Berrou, JP; Goch, JH; Hanon, O; Nádházi, Z; Negre-Pages, L; Pathak, A; Petrella, R; Sedefdjian, A; Sévenier, F; Shlyakhto, EV | 1 |
Blankestijn, PJ; Rupp, H | 1 |
Albert, DH; Banfor, PN; Cox, BF; Davidsen, SK; Franklin, PH; Fryer, RM; Gintant, GA; Larson, KJ; Noonan, WT; Segreti, JA; Tapang, P; Widomski, DL | 1 |
Calderone, A; Gillis, MA; Gutkowska, J; Jankowski, M; Menaouar, A; Mukaddam-Daher, S; Paquette, PA; Shi, YF; Tardif, JC | 1 |
Beltrán, B; Dasi, F; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Muñoz, A | 1 |
Dowlatshahi, D; Hill, MD | 1 |
Diener, HC; Gradl, B; Greiner, W; Jönsson, B; Lindgren, P; Lüders, S; Schrader, J; Schwander, B; Villar, FA; Zöllner, Y | 1 |
Domínguez-Gil, A; Gregori, JA; Nuñez, JF | 1 |
Enikeev, AKh; Kolomoets, NM; Zamotaev, IuN | 1 |
Derosa, G; Ferrari, I; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
Pan, Y; Sun, C; Wang, D; Wu, J | 1 |
Plosker, GL | 1 |
Hartog, JW; Jaarsma, W; Miyata, T; Plokker, HW; Schalkwijk, CG; Smit, AJ; van de Wal, RM; van Veldhuisen, DJ; van Wijk, LM; Voors, AA | 1 |
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J | 1 |
Hartog, JW; Hummel, YM; Jaarsma, W; Plokker, TW; van de Wal, RM; van Veldhuisen, DJ; Vijn, RG; Voors, AA | 1 |
Ambrosioni, E; Bombelli, M; Cerasola, G; Cipollone, F; Ferri, C; Grazioli, I; Leprotti, C; Mancia, G; Melzi, G; Mugellini, A; Mulè, G; Palasciano, G; Salvetti, A; Trimarco, B | 1 |
Kahner-Gröne, S; Köneke, D; Marggraf, K; Nüdling, S; Palissa, H | 1 |
Li, H; Shi, D; Shi, XY; Xu, FY; Yang, B; Zou, Z | 1 |
Berrou, JP; Choueiry, P; Eid, E; Ismail, A; Pathak, A; Radaideh, GA; Sedefdjian, A; Sévenier, F | 1 |
De Backer, G; Goudev, AR; Pathak, A; Petrella, RJ; Radaideh, GA; Rynkiewicz, A | 1 |
Berrou, JP; Konradi, AO; Pathak, A; Petrella, RJ; Sedefdjian, A; Shlyakhto, E | 1 |
Hacioğlu, F; Onal, A | 1 |
Zamotaev, IuN | 1 |
Fullana-Monllor, J; Martinez-Moragón, E; Pérez-Lluna, L | 1 |
Berrou, JP; Goudev, A; Pathak, A | 1 |
Ackaert, O; Koopmans, RP; Mathôt, RA; Ploeger, BA; Snelder, N; van Hest, RM; van Rijn-Bikker, PC | 1 |
Hanon, O; Lee, YS; Pathak, A | 1 |
Grankina, VIu; Kaliuzhin, VV; Kaliuzhina, EV; Sazonov, ÉA; Sibireva, OF; Tkalich, LM; Urazova, OI; Zibnitskaia, LI | 1 |
De Backer, G; Gill, DP; Petrella, RJ; Tremblay, G | 1 |
Dohmen, PM; Konertz, W; Modersohn, D; Patil, NP; Sabashnikov, A; Weymann, A | 1 |
Asner, R; Bayer, A; Kopf, W; Letzel, M; Schüssler, W; Sengl, M; Weiß, K | 1 |
Huo, X; Liu, K; Liu, Q; Meng, Q; Sun, H; Sun, P; Wang, C; Zhang, A | 1 |
Devrukhakar, PS; Gaitonde, VD; Kalariya, PD; Kumar Talluri, MV; Srinivas, R | 1 |
Bao, X; Chen, J; Ding, X; Wang, C; Wang, W; Wang, Y; Zhang, F; Zhou, J | 1 |
Chen, C; Du, J; Li, HH; Meng, Y; Tian, C | 1 |
Heeba, GH; Mahmoud, ME; Morsy, MA | 1 |
Hehemann, K; Maier, H; Vieth, M | 1 |
Bao, X; Ding, X; Ding, Y; Li, M; Wang, C; Wang, W; Wu, Y; Xiong, H; Yang, T; Zhou, J | 1 |
Ah, YM; Choi, KH; Choi, YJ; Han, N; Kim, B; Kong, J; Lee, HY; Lee, JY; Oh, JM; Shin, WG; Yu, YM | 1 |
de Leeuw, PW; Houben, AJ; Kroon, AA; van Twist, DJ | 1 |
Dangre, P; Dhole, S; Gilhotra, R | 1 |
Ostroumova, OD; Pervichko, EI; Zinchenko, YP | 1 |
Karnik, SS; Node, K; Takezako, T; Unal, H | 1 |
Pokharkar, V; Shekhawat, P | 1 |
Abdelsalam, RA; Haddad, GM; Marghany, KA | 1 |
Leonova, GN; Lubova, VA; Maistrovskaya, OS | 1 |
Anitha, P; Babu, D; Gayathri, R; Mohan, S; Ramkanth, S | 1 |
Al-Shorbagy, M; El-Naggar, R; El-Yamany, MF; Fahmy, MIM; Hegazy, AAE; Saad, MAE; Sayed, RH | 1 |
Majer, J; Masajtis-Zagajewska, A; Nowicki, M | 1 |
Abdul-Aziz, AA; Elshehawy, AA; Koutb, F; Mehany, H; Shaban, NZ; Zaki, MM | 1 |
Ahad, A; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Bin Jardan, YA; Hassan, MZ; Raish, M | 1 |
Berto-Junior, C; Guimarães-Nobre, CC; Mendonça-Reis, E; Miranda-Alves, L; Teixeira-Alves, LR | 1 |
44 review(s) available for thiophenes and eprosartan
Article | Year |
---|---|
Angiotensin II receptors and functional correlates.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Imidazoles; Losartan; Pyridines; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Thiophenes | 1992 |
The angiotensin II type 1 receptor antagonists. A new class of antihypertensive drugs.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Pyridines; Quinolines; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 1995 |
Eprosartan.
Topics: Acrylates; Antihypertensive Agents; Humans; Imidazoles; Randomized Controlled Trials as Topic; Thiophenes | 1998 |
Angiotensin II receptor pharmacology and AT1-receptor blockers.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes | 1999 |
Pharmacokinetics of eprosartan in healthy subjects, patients with hypertension, and special populations.
Topics: Absorption; Acrylates; Age Factors; Antihypertensive Agents; Biological Availability; Clinical Trials, Phase III as Topic; Humans; Hypertension; Imidazoles; Sex Factors; Thiophenes | 1999 |
A review of eprosartan pharmacokinetic and pharmacodynamic drug interaction studies.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Drug Interactions; Humans; Imidazoles; Randomized Controlled Trials as Topic; Thiophenes | 1999 |
The renal profile of eprosartan.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Imidazoles; Male; Randomized Controlled Trials as Topic; Thiophenes | 1999 |
Clinical efficacy of eprosartan.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Imidazoles; Randomized Controlled Trials as Topic; Thiophenes | 1999 |
Safety and tolerability of eprosartan.
Topics: Acrylates; Antihypertensive Agents; Clinical Trials as Topic; Drug Tolerance; Humans; Hypertension; Imidazoles; Thiophenes | 1999 |
Management of hypertension: the advent of a new angiotensin II receptor antagonist.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Enalapril; Humans; Hypertension; Imidazoles; Survival Rate; Thiophenes; Treatment Outcome | 1999 |
Pharmacological mechanism of angiotensin II receptor antagonists: implications for the treatment of elevated systolic blood pressure.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Sympathetic Nervous System; Systole; Thiophenes; Treatment Outcome; Vascular Resistance | 1999 |
Safety and efficacy of eprosartan, a new angiotensin II receptor blocker.
Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Drug Interactions; Humans; Hypertension; Imidazoles; Thiophenes | 1999 |
Pharmacology of eprosartan, an angiotensin II receptor antagonist: exploring hypotheses from clinical data.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hypertension; Imidazoles; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 1999 |
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes | 2000 |
Eprosartan: a review of its use in the management of hypertension.
Topics: Acrylates; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Thiophenes | 2000 |
Control of cardiomyocyte gene expression as drug target.
Topics: Acrylates; Amino Acid Sequence; Animals; Antihypertensive Agents; Calcium-Transporting ATPases; Catecholamines; Gene Expression Regulation; Heart Failure; Humans; Hypertension; Imidazoles; Molecular Sequence Data; Myocardium; Myosin Heavy Chains; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sequence Alignment; Sequence Homology, Amino Acid; Thiophenes | 2000 |
[Prospects for pharmacological effects on renin-angiotensin and sympathetic nervous systems in patients with arterial hypertension].
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 2000 |
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan | 2001 |
[Angiotensin receptor blockers--significance for the therapy of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Prodrugs; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Valine; Valsartan | 2001 |
Issues in hypertension: drug tolerability and special populations.
Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Interactions; Humans; Hypertension; Imidazoles; Middle Aged; Patient Compliance; Receptors, Angiotensin; Thiophenes; United States | 2001 |
Pharmacology and clinical efficacy of angiotensin receptor blockers.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Treatment Outcome | 2001 |
Differentiation in the angiotensin II receptor 1 blocker class on autonomic function.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autonomic Nervous System Diseases; Heart Rate; Humans; Imidazoles; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 2001 |
Potential of the angiotensin II receptor 1 blocker eprosartan in the management of patients with hypertension or heart failure.
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Heart Failure; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Treatment Outcome | 2001 |
Angiotensin II antagonists in systolic blood pressure control.
Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Blood Pressure; Delivery of Health Care; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Systole; Thiophenes | 2001 |
[Irbesartan: a new possibility in the treatment of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2002 |
Safety and tolerability of eprosartan in combination with hydrochlorothiazide.
Topics: Acrylates; Age Factors; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Thiophenes | 2002 |
The clinical profile of the angiotensin II receptor blocker eprosartan.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Thiophenes | 2002 |
[Policy of antihypertensive therapy in arterial hypertension in the elderly. II].
Topics: Acrylates; Adrenergic alpha-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Perindopril; Risk Factors; Sex Factors; Sodium Chloride Symporter Inhibitors; Thiophenes | 2002 |
Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation.
Topics: Acrylates; Aged; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Coronary Artery Disease; Data Interpretation, Statistical; Diabetes Mellitus; E-Selectin; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Thiophenes; Vasculitis | 2002 |
Clinical profile of eprosartan.
Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Humans; Imidazoles; Renin-Angiotensin System; Thiophenes; Treatment Outcome | 2002 |
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2 | 2003 |
[Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2003 |
[Neurocirculatory dystonia (does this disease exist?)].
Topics: Acrylates; Adolescent; Adult; Antihypertensive Agents; Child; Clinical Trials as Topic; Diagnosis, Differential; Female; Humans; Imidazoles; Male; Neurocirculatory Asthenia; Psychotherapy; Stress, Psychological; Thiophenes | 2003 |
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2004 |
Eprosartan: a review of its use in the management of hypertension.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Imidazoles; Thiophenes | 2005 |
Effects of eprosartan on target organ protection.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Neuroprotective Agents; Nitrendipine; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Research Design; Risk Factors; Stroke; Thiophenes; Treatment Outcome | 2006 |
An update on non-peptide angiotensin receptor antagonists and related RAAS modulators.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Endothelin Receptor Antagonists; Humans; Hypertension; Imidazoles; Losartan; Protease Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2; Renin; Renin-Angiotensin System; Thiophenes | 2007 |
Unique dual mechanism of action of eprosartan: effects on systolic blood pressure, pulse pressure, risk of stroke and cognitive decline.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Cognition Disorders; Female; Humans; Hypertension; Imidazoles; Male; Sensitivity and Specificity; Severity of Illness Index; Stroke; Survival Analysis; Systole; Thiophenes; Treatment Outcome | 2007 |
Angiotensin blockade with eprosartan: vascular and functional implications.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atherosclerosis; Humans; Imidazoles; Kidney Diseases; Platelet Aggregation; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Ventricular Dysfunction, Left | 2007 |
Observational Study on Cognitive function And systolic blood pressure Reduction (OSCAR): preliminary analysis of 6-month data from > 10,000 patients and review of the literature.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Animals; Cognition Disorders; Dementia, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Rats; Stroke; Thiophenes | 2007 |
Risk reduction by preventing stroke: need for blockade of angiotensin II and catecholamines?
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Catecholamines; Humans; Hypertension; Imidazoles; Norepinephrine; Stroke; Tetrazoles; Thiophenes; Valine; Valsartan | 2007 |
Clinical profile of eprosartan: a different angiotensin II receptor blocker.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension; Imidazoles; Kidney Diseases; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 2008 |
Eprosartan: a review of its use in hypertension.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Clinical Trials as Topic; Cough; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Nitrendipine; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Recurrence; Risk Factors; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome | 2009 |
Antihypertensive effects and safety of eprosartan: a meta-analysis of randomized controlled trials.
Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Randomized Controlled Trials as Topic; Thiophenes | 2012 |
77 trial(s) available for thiophenes and eprosartan
Article | Year |
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Eprosartan, an angiotensin II receptor antagonist, does not affect the pharmacodynamics of glyburide in patients with type II diabetes mellitus.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Interactions; Female; Glyburide; Humans; Hypoglycemic Agents; Imidazoles; Male; Middle Aged; Sweating; Thiophenes | 1997 |
Lack of effect of eprosartan on the single dose pharmacokinetics of orally administered digoxin in healthy male volunteers.
Topics: Acrylates; Administration, Oral; Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Digoxin; Drug Interactions; Humans; Imidazoles; Iodine Radioisotopes; Isotope Labeling; Male; Radioimmunoassay; Receptors, Angiotensin; Thiophenes | 1997 |
Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers.
Topics: Acrylates; Adult; Antifungal Agents; Antihypertensive Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Fluconazole; Humans; Imidazoles; Losartan; Male; Middle Aged; Reference Values; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tetrazoles; Thiophenes; Time Factors | 1997 |
Effect of ranitidine on the pharmacokinetics of orally administered eprosartan, an angiotensin II antagonist, in healthy male volunteers.
Topics: Acrylates; Administration, Oral; Adult; Angiotensin II; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Histamine H2 Antagonists; Humans; Imidazoles; Male; Ranitidine; Thiophenes | 1998 |
A dose-response study to assess the renal hemodynamic, vascular, and hormonal effects of eprosartan, an angiotensin II AT1-receptor antagonist, in sodium-replete healthy men.
Topics: Acrylates; Adult; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Humans; Imidazoles; Male; Potassium, Dietary; Reference Values; Renal Circulation; Sodium, Dietary; Thiophenes; Time Factors | 1998 |
A dose proportionality study of eprosartan in healthy male volunteers.
Topics: Acrylates; Adult; Antihypertensive Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Imidazoles; Male; Thiophenes | 1998 |
The effects of eprosartan, an angiotensin II AT1 receptor antagonist, on uric acid excretion in patients with mild to moderate essential hypertension.
Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Creatinine; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Imidazoles; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Thiophenes; Uric Acid | 1998 |
Eprosartan does not affect the pharmacodynamics of warfarin.
Topics: Acrylates; Adult; Anticoagulants; Antihypertensive Agents; Double-Blind Method; Drug Interactions; Humans; Imidazoles; International Normalized Ratio; Male; Middle Aged; Thiophenes; Warfarin | 1998 |
Pharmacokinetics of intravenously and orally administered eprosartan in healthy males: absolute bioavailability and effect of food.
Topics: Acrylates; Administration, Oral; Adult; Analysis of Variance; Antihypertensive Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Dietary Fats; Food-Drug Interactions; Half-Life; Humans; Imidazoles; Injections, Intravenous; Male; Thiophenes | 1998 |
The efficacy and tolerance of one or two daily doses of eprosartan in essential hypertension. The Eprosartan Multinational Study Group.
Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes; Treatment Outcome | 1999 |
Effect of long-term eprosartan versus enalapril antihypertensive therapy on left ventricular mass and coronary flow reserve in stage I-II hypertension. Eprosartan Study Group.
Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Circulation; Double-Blind Method; Enalapril; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Thiophenes | 1999 |
Effect of eprosartan and enalapril in the treatment of elderly hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Age Factors; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Thiophenes | 1999 |
Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Renin; Thiophenes | 1999 |
Effect of eprosartan and enalapril in the treatment of black hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes | 1999 |
Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Eprosartan Study Group.
Topics: Acrylates; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Placebos; Prospective Studies; Sex Factors; Thiophenes | 1999 |
Pharmacokinetics and protein binding of eprosartan in hemodialysis-dependent patients with end-stage renal disease.
Topics: Acrylates; Adult; Antihypertensive Agents; Female; Humans; Imidazoles; Male; Middle Aged; Protein Binding; Renal Dialysis; Renal Insufficiency; Thiophenes | 1999 |
Double-blind comparison of eprosartan and enalapril on cough and blood pressure in unselected hypertensive patients. Eprosartan Study Group.
Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cough; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Risk Factors; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Surveys and Questionnaires; Thiophenes; Treatment Outcome | 1999 |
Effect of eprosartan and losartan on uric acid metabolism in patients with essential hypertension.
Topics: Acrylates; Administration, Oral; Aged; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes; Uric Acid | 1999 |
Efficacy and safety of eprosartan in severe hypertension. Eprosartan Multinational Study Group.
Topics: Acrylates; Administration, Oral; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Thiophenes | 1999 |
Improvement of cardiac output in patients with severe heart failure by use of ACE-inhibitors combined with the AT1-antagonist eprosartan.
Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiac Output; Drug Therapy, Combination; Female; Heart Failure; Humans; Imidazoles; Male; Middle Aged; Pilot Projects; Thiophenes; Ventricular Function, Left | 2000 |
ADEPT: Addition of the AT1 receptor antagonist eprosartan to ACE inhibitor therapy in chronic heart failure trial: hemodynamic and neurohormonal effects.
Topics: Acrylates; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial Natriuretic Factor; Biomarkers; Catheterization, Swan-Ganz; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Prognosis; Prospective Studies; Radionuclide Ventriculography; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Safety; Thiophenes | 2001 |
Eprosartan provides safe and effective long-term maintenance of blood pressure control in patients with mild to moderate essential hypertension.
Topics: Acrylates; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Canada; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome; United States | 2001 |
Comparison of quality of life and cough on eprosartan and enalapril in people with moderate hypertension.
Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Double-Blind Method; Drug Administration Schedule; Enalapril; Europe; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Incidence; Male; Middle Aged; North America; Probability; Prospective Studies; Quality of Life; Risk Factors; Severity of Illness Index; South Africa; Thiophenes; Treatment Outcome | 2001 |
Quality of life and cough on antihypertensive treatment: a randomised trial of eprosartan, enalapril and placebo.
Topics: Acrylates; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Double-Blind Method; Drug Administration Schedule; Enalapril; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Probability; Quality of Life; Reference Values; Risk Assessment; Severity of Illness Index; Thiophenes; Treatment Outcome | 2001 |
Evaluation of the 24-hour blood pressure effects of eprosartan in patients with systemic hypertension.
Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes | 2001 |
Eprosartan versus enalapril in elderly patients with hypertension: a double-blind, randomized trial.
Topics: Acrylates; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Maximum Tolerated Dose; Therapeutic Equivalency; Thiophenes; Treatment Outcome | 2001 |
Efficacy of eprosartan in combination with HCTZ in patients with essential hypertension.
Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes | 2002 |
Effects of enalapril and eprosartan on the renal vascular nitric oxide system in human essential hypertension.
Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Vessels; Double-Blind Method; Drug Combinations; Enalapril; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Nitric Oxide; omega-N-Methylarginine; Receptor, Angiotensin, Type 1; Renal Circulation; Thiophenes | 2002 |
Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension.
Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginine; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Thiophenes | 2002 |
AT1 blockers and uric acid metabolism: are there relevant differences?
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Double-Blind Method; Humans; Hypertension; Imidazoles; Losartan; Receptor, Angiotensin, Type 1; Thiophenes; Uric Acid | 2002 |
[Metabolic effects of angiotensin-II receptor blockers].
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cholesterol; Endothelium, Vascular; Fibrin; Humans; Hypertension; Imidazoles; Male; Receptors, Angiotensin; Thiophenes | 2002 |
Effects of isosorbide mononitrate and AII inhibition on pulse wave reflection in hypertension.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Imidazoles; Isosorbide Dinitrate; Male; Middle Aged; Pulse; Thiophenes; Time Factors; Vasodilator Agents | 2003 |
Effects of angiotensin II receptor antagonism on the renal hemodynamic response to cardiovascular stress.
Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endocrine Glands; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Imidazoles; Lower Body Negative Pressure; Male; Renal Circulation; Severity of Illness Index; Thiophenes | 2003 |
Elevation of sympathetic activity by eprosartan in young male subjects.
Topics: Acrylates; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Imidazoles; Lower Body Negative Pressure; Male; Muscle, Skeletal; Norepinephrine; Prospective Studies; Stress, Psychological; Sympathetic Nervous System; Thiophenes | 2003 |
AT1 antagonism by eprosartan lowers heart rate variability and baroreflex gain.
Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Baroreflex; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Imidazoles; Male; Prospective Studies; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thiophenes | 2003 |
[Antihypertensive treatment with eprosartan mesilate of patients in acute and late periods of ischemic stroke].
Topics: Acrylates; Acute Disease; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chi-Square Distribution; Data Interpretation, Statistical; Diastole; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Middle Aged; Quality of Life; Recurrence; Stroke; Systole; Thiophenes; Time Factors | 2003 |
[Effect of eprosartan on microcirculation and blood rheology in patients with hypertensive disease].
Topics: Acrylates; Adult; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Male; Microcirculation; Middle Aged; Rheology; Thiophenes; Treatment Outcome | 2004 |
[Comparison of eprosartan and captopril in left ventricular systolic dysfunction: relation of efficacy to myocardial viability].
Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Systole; Thiophenes; Ventricular Dysfunction, Left | 2004 |
Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertension: data from a 13-week double-blind, placebo-controlled, parallel, multicenter study.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome | 2004 |
Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind, placebo-controlled 12-month study.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Glucose; Homeostasis; Humans; Hypertension; Imidazoles; Lipids; Male; Middle Aged; Telmisartan; Thiophenes | 2004 |
A double blind randomized trial to compare the effects of eprosartan and enalapril on blood pressure, platelets, and endothelium function in patients with essential hypertension.
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Endothelium, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Platelet Activation; Prospective Studies; Thiophenes | 2004 |
Effect of eprosartan on cytoplasmic free calcium mobilization, platelet activation, and microparticle formation in hypertension.
Topics: Acrylates; Adult; Antihypertensive Agents; Blood Pressure; Calcium; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Particle Size; Platelet Activation; Prospective Studies; Stress, Mechanical; Thiophenes | 2004 |
Eprosartan effect on fibrinolytic/hemostatic variables in arterial hypertension: a comparative study to losartan.
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Drug Administration Schedule; Female; Fibrinogen; Fibrinolysis; Follow-Up Studies; Hemostasis; Humans; Hypertension; Imidazoles; Lipoproteins; Losartan; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Thiophenes; Thrombomodulin; Time Factors; Tissue Plasminogen Activator | 2004 |
Effect of eprosartan on catecholamines and peripheral haemodynamics in subjects with insulin-induced hypoglycaemia.
Topics: Acrylates; Administration, Oral; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; Epinephrine; Forearm; Heart Rate; Hemodynamics; Humans; Hypoglycemia; Imidazoles; Insulin; Male; Norepinephrine; Thiophenes | 2005 |
Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure.
Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imidazoles; Kidney Failure, Chronic; Male; Middle Aged; Muscle, Skeletal; Sympathetic Nervous System; Sympatholytics; Thiophenes | 2004 |
Losartan increases bradykinin levels in hypertensive humans.
Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes | 2005 |
Effectiveness and safety of eprosartan on pulse pressure for the treatment of hypertensive patients.
Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Pulse; Thiophenes; Treatment Outcome | 2005 |
Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES).
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium; Cardiovascular Diseases; Female; Humans; Hypertension; Imidazoles; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nitrendipine; Prospective Studies; Recurrence; Risk Factors; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Stroke; Thiophenes; Time Factors; Treatment Outcome | 2005 |
[Effect of a combination of teveten and prestarium in patients with chronic heart failure].
Topics: Acrylates; Antihypertensive Agents; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; Humans; Imidazoles; Male; Perindopril; Thiophenes | 2005 |
Haemodynamic effects of eprosartan and valsartan in hypertensive patients during isometric and mental stress.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Female; Forearm; Hand Strength; Heart Rate; Humans; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Skin; Stress, Psychological; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome; Valine; Valsartan | 2005 |
Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension.
Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cross-Over Studies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Norepinephrine; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 2006 |
Morbidity and mortality after stroke--eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES).
Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Data Interpretation, Statistical; Diuretics; Humans; Imidazoles; Internal Medicine; Ischemic Attack, Transient; Morbidity; Neurology; Nitrendipine; Prospective Studies; Stroke; Thiophenes | 2006 |
MOSES raises questions.
Topics: Acrylates; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Data Interpretation, Statistical; Humans; Imidazoles; Ischemic Attack, Transient; Nitrendipine; Research Design; Risk Factors; Stroke; Thiophenes | 2006 |
Atenolol and eprosartan: differential effects on central blood pressure and aortic pulse wave velocity.
Topics: Acrylates; Antihypertensive Agents; Aorta, Thoracic; Atenolol; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Pulsatile Flow; Receptor, Angiotensin, Type 1; Thiophenes; Treatment Outcome | 2006 |
Effect of eprosartan on the sympathetic response to cold pressor test in healthy volunteers.
Topics: Acrylates; Administration, Oral; Adolescent; Adult; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cold Temperature; Double-Blind Method; Female; Heart Rate; Humans; Imidazoles; Losartan; Male; Middle Aged; Sympathetic Nervous System; Thiophenes; Time Factors | 2006 |
Eprosartan mesylate effectively reduces systolic and diastolic blood pressure in a Canadian primary care setting.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Blood Pressure Determination; Canada; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Probability; Prospective Studies; Reference Values; Severity of Illness Index; Single-Blind Method; Systole; Thiophenes; Treatment Outcome | 2004 |
The angiotensin receptor blocker eprosartan mesylate reduces pulse pressure in isolated systolic hypertension.
Topics: Acrylates; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Canada; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Probability; Reference Values; Severity of Illness Index; Systole; Thiophenes; Treatment Outcome | 2004 |
[Effect of eprosartan on psychophysiological functions of drivers with arterial hypertension].
Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension; Imidazoles; Male; Middle Aged; Occupational Diseases; Railroads; Thiophenes | 2006 |
[Role of the renin-angiotensin system on the sympathetic response induced by the cold pressor test in humans].
Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cold Temperature; Double-Blind Method; Female; Humans; Imidazoles; Losartan; Male; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan | 2007 |
Effects of different AT1-receptor antagonists in the therapy of severe heart failure pretreated with ACE inhibitors.
Topics: Acrylates; Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biomarkers; Biphenyl Compounds; Blood Pressure; Cardiac Output; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Imidazoles; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Vascular Resistance | 2007 |
[The effectiveness of eprosartan in patients with chronic glomerulonephritis].
Topics: Acrylates; Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Female; Glomerulonephritis; Humans; Imidazoles; Male; Thiophenes | 2007 |
Observational Study on Cognitive function And systolic blood pressure Reduction (OSCAR): preliminary analysis of 6-month data from > 10,000 patients and review of the literature.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Animals; Cognition Disorders; Dementia, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Rats; Stroke; Thiophenes | 2007 |
Eprosartan modulates the reflex activation of the sympathetic nervous system in sodium restricted healthy humans.
Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diet, Sodium-Restricted; Female; Glomerular Filtration Rate; Humans; Imidazoles; Male; Natriuresis; Sodium, Dietary; Sympathetic Nervous System; Thiophenes | 2008 |
Effects of eprosartan on mitochondrial membrane potential and H2O2 levels in leucocytes in hypertension.
Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydrogen Peroxide; Hypertension; Imidazoles; Leukocytes; Male; Membrane Potential, Mitochondrial; Middle Aged; Oxidative Stress; Pilot Projects; Rhodamines; tert-Butylhydroperoxide; Thiophenes | 2008 |
[Effect of antihypertensive drugs of various pharmacological groups on reaction of arterial pressure under conditions of stree testing. Part II. Value of various strategies of potentiation of systemic vasodilatation].
Topics: Acrylates; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exercise Test; Follow-Up Studies; Humans; Hypertension; Imidazoles; Lisinopril; Middle Aged; Propanolamines; Receptor, Angiotensin, Type 1; Thiophenes; Treatment Outcome; Vasodilation | 2008 |
Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: primary results of the Observational Study on Cognitive function And Systolic Blood Pressure Reduction open-label study.
Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Cognition; Cognition Disorders; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Thiophenes; Treatment Outcome | 2008 |
Superoxide dismutase and catalase anti-oxidant activity in leucocyte lysates from hypertensive patients: effects of eprosartan treatment.
Topics: Acrylates; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Cell Extracts; Female; Heart Rate; Humans; Hypertension; Imidazoles; Leukocytes; Male; Middle Aged; Superoxide Dismutase; Thiophenes | 2009 |
Costs of eprosartan versus diuretics for treatment of hypertension in a geriatric population: an observational, open-label, multicentre study.
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Costs and Cost Analysis; Diuretics; Female; Geriatrics; Humans; Hypertension; Imidazoles; Male; Thiophenes | 2009 |
Comparative effects of telmisartan and eprosartan on insulin sensitivity in the treatment of overweight hypertensive patients.
Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Glucose; Female; Humans; Hypertension; Imidazoles; Insulin; Male; Middle Aged; Overweight; Telmisartan; Thiophenes | 2009 |
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diastole; Female; Glycation End Products, Advanced; Humans; Hypertension; Imidazoles; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Skin; Statistics as Topic; Statistics, Nonparametric; Stroke Volume; Thiophenes; Ventricular Function, Left | 2010 |
Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.
Topics: Acrylates; Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diastole; Echocardiography; Female; Heart; Humans; Hypertension; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Stroke Volume; Thiophenes; Treatment Outcome; Ventricular Dysfunction; Ventricular Function; Ventricular Function, Left | 2010 |
Ambulatory monitoring of systolic hypertension in the elderly: Eprosartan/hydrochlorothiazide compared with losartan/hydrochlorothiazide (INSIST trial).
Topics: Acrylates; Aged; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Office Visits; Severity of Illness Index; Statistics, Nonparametric; Systole; Thiophenes; Treatment Outcome | 2010 |
[Adjustment of antihypertensive therapy to a generic eprosartan preparation. Results of a non-interventional study].
Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cost Savings; Drug Combinations; Drug Costs; Drug Substitution; Drugs, Generic; Female; Humans; Hydrochlorothiazide; Imidazoles; Male; Middle Aged; National Health Programs; Prospective Studies; Thiophenes | 2010 |
Eprosartan-based hypertension therapy, systolic arterial blood pressure and cognitive function: analysis of Middle East data from the OSCAR study.
Topics: Acrylates; Aged; Analysis of Variance; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Arabs; Blood Pressure; Chi-Square Distribution; Cognition; Female; Humans; Hypertension; Imidazoles; Logistic Models; Male; Middle Aged; Middle East; Psychiatric Status Rating Scales; Thiophenes; Time Factors; Treatment Outcome | 2011 |
Pharmacokinetic-pharmacodynamic modeling of the antihypertensive effect of eprosartan in Black and White hypertensive patients.
Topics: Acrylates; Adult; Antihypertensive Agents; Black People; Blood Pressure; Cross-Over Studies; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Models, Biological; Thiophenes; White People | 2013 |
[Effect of eprosartan on the hemostatic system in patients with chronic kidney disease associated with hereditary thrombophilia].
Topics: Acrylates; Adult; Angiotensin II Type 2 Receptor Blockers; Female; Hemostasis; Humans; Imidazoles; Male; Renal Insufficiency, Chronic; Thiophenes; Thrombophilia; Treatment Outcome; Young Adult | 2013 |
Losartan and Eprosartan Induce a Similar Effect on the Acute Rise in Serum Uric Acid Concentration after an Oral Fructose Load in Patients with Metabolic Syndrome.
Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Fructose; Humans; Hypertension; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged; Thiophenes; Uric Acid | 2021 |
137 other study(ies) available for thiophenes and eprosartan
Article | Year |
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Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Calcium; Consciousness; Humans; Imidazoles; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Inbred Strains; Thiophenes; Vasoconstriction | 1992 |
Effect of captopril and the nonpeptide angiotensin II antagonists, SK&F 108566 and EXP3174, on renal function in dogs with a renal artery stenosis.
Topics: Acrylates; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Imidazoles; Inulin; Kidney; Losartan; Regional Blood Flow; Renal Artery Obstruction; Tetrazoles; Thiophenes | 1992 |
The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Decerebrate State; Enalapril; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Spinal Cord; Tetrazoles; Thiophenes | 1992 |
Characterization of renal angiotensin II receptors using subtype selective antagonists.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Thiophenes | 1992 |
Renin-angiotensin system inhibition reduces glycine-induced glomerular hyperfiltration in conscious rats.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Enalapril; Glomerular Filtration Rate; Glycine; Imidazoles; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Renal Circulation; Renin-Angiotensin System; Thiophenes | 1992 |
Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs.
Topics: Acrylates; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dogs; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Thiophenes | 1992 |
1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Dogs; Imidazoles; In Vitro Techniques; Indicators and Reagents; Kidney; Molecular Conformation; Molecular Structure; Muscle, Smooth, Vascular; Rabbits; Rats; Receptors, Angiotensin; Structure-Activity Relationship; Thiophenes; Vasoconstriction | 1991 |
Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.
Topics: Acrylates; Amino Acid Sequence; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Binding Sites; Cells, Cultured; Histidine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis; Rats; Receptors, Angiotensin; Thiophenes | 1995 |
Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Endothelins; Glycopeptides; Imidazoles; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes | 1994 |
Imidazole based non-peptide angiotensin II receptor antagonists. Investigation of the effect of the orientation of the imidazole ring on biological activity.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Imidazoles; In Vitro Techniques; Losartan; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetrazoles; Thiophenes; Uterine Contraction | 1993 |
Nonpeptide angiotensin II receptor antagonists: potential advantages over ACE inhibitors.
Topics: Acrylates; Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cough; Dogs; Enalapril; Female; Glomerular Filtration Rate; Imidazoles; Male; Renal Circulation; Thiophenes | 1993 |
Characterization of bovine ovary angiotensin II receptors using subtype-selective antagonists.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cattle; Female; Imidazoles; In Vitro Techniques; Oligopeptides; Ovary; Pyridines; Receptors, Angiotensin; Thiophenes | 1993 |
Characterization of [3H]SK&F 108566 as a radioligand for angiotensin type-1 receptor.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Imidazoles; Male; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes | 1993 |
Potent nonpeptide angiotensin II receptor antagonists. 2. 1-(Carboxybenzyl)imidazole-5-acrylic acids.
Topics: Acrylates; Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Rabbits; Rats; Structure-Activity Relationship; Thiophenes | 1993 |
Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Hydrogen-Ion Concentration; Imidazoles; Kidney; Kinetics; Losartan; Male; Microvilli; Naphthalenes; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiophenes; Uric Acid | 1996 |
Short-term exposure to lipopolysaccharide is associated with microvascular contractile dysfunction in vivo.
Topics: Acrylates; Allopurinol; Animals; Antihypertensive Agents; Arginine; Arterioles; Cheek; Cricetinae; Imidazoles; Indomethacin; Lipopolysaccharides; Male; Mesocricetus; Nitroarginine; Thiophenes; Vasoconstriction; Vasodilation | 1995 |
Renal hemodynamic response to an angiotensin II antagonist, eprosartan, in healthy men.
Topics: Acrylates; Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Diet, Sodium-Restricted; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Natriuresis; Reference Values; Renal Circulation; Renin; Thiophenes | 1997 |
Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: relationship to differences in prejunctional angiotensin II receptor blockade.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan | 1997 |
Pharmacokinetics and protein binding of eprosartan in healthy volunteers and in patients with varying degrees of renal impairment.
Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Area Under Curve; Humans; Imidazoles; Metabolic Clearance Rate; Middle Aged; Renal Insufficiency; Thiophenes | 1998 |
Determination of SK&F 108566 (Teveten) in human plasma by reversed-phase high-performance liquid chromatography.
Topics: Acrylates; Angiotensin II; Calibration; Chromatography, High Pressure Liquid; Humans; Imidazoles; Indicators and Reagents; Quality Control; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Thiophenes | 1998 |
Angiotensin II signaling activities the NO-cGMP pathway in rat proximal tubules.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cyclic GMP; Imidazoles; Kidney Tubules, Proximal; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiophenes | 1998 |
Effect of age and gender on the pharmacokinetics of eprosartan.
Topics: Acrylates; Adult; Aged; Aging; Antihypertensive Agents; Area Under Curve; Female; Half-Life; Humans; Imidazoles; Male; Middle Aged; Premenopause; Protein Binding; Sex Factors; Thiophenes | 1998 |
Effects of eprosartan on renal function and cardiac hypertrophy in rats with experimental heart failure.
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Heart Failure; Hemodynamics; Imidazoles; Kidney; Male; Rats; Rats, Wistar; Renal Circulation; Sodium; Thiophenes | 1998 |
The evolving role of angiotensin-II receptor blockers in cardiovascular risk reduction. Case study.
Topics: Acrylates; Adult; Antihypertensive Agents; Black People; Enalapril; Female; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Thiophenes | 1998 |
Review of eprosartan: a new angiotensin II receptor antagonist. Introduction.
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Imidazoles; Thiophenes | 1999 |
Review of eprosartan: a new angiotensin II receptor antagonist. Summary.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Imidazoles; Kidney; Renal Circulation; Thiophenes | 1999 |
ACE inhibition and glucose transport in insulinresistant muscle: roles of bradykinin and nitric oxide.
Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Female; Glucose; Imidazoles; Insulin Resistance; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker; Thiophenes | 1999 |
Effects of eprosartan on glomerular injury in rats with reduced renal mass.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Drug Evaluation, Preclinical; Glomerulosclerosis, Focal Segmental; Imidazoles; Male; Nephrectomy; Proteinuria; Rats; Thiophenes; Vasoconstrictor Agents | 1999 |
Dehydration behavior of eprosartan mesylate dihydrate.
Topics: Acrylates; Algorithms; Antihypertensive Agents; Calorimetry, Differential Scanning; Crystallization; Desiccation; Drug Stability; Hydrogen Bonding; Imidazoles; Kinetics; Models, Molecular; Particle Size; Tablets; Temperature; Thermogravimetry; Thiophenes; X-Ray Diffraction | 1999 |
A new ACE inhibitor and two new angiotensin receptor blockers for hypertension.
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Clinical Trials as Topic; Contraindications; Double-Blind Method; Half-Life; Humans; Hypertension; Imidazoles; Perindopril; Telmisartan; Thiophenes | 1999 |
[Stroke prevention. Is there an added value to RAS inhibition?].
Topics: Acrylates; Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Rats; Stroke; Thiophenes | 2000 |
Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan | 2000 |
In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Irbesartan; Losartan; Microsomes, Liver; Protein Isoforms; Tetrazoles; Thiophenes; Valine; Valsartan | 2000 |
Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans.
Topics: Acrylates; Adult; Angiotensin II; Diabetic Nephropathies; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperglycemia; Imidazoles; Kidney; Male; Middle Aged; Renal Circulation; Renin; Renin-Angiotensin System; Thiophenes | 2000 |
Gene expression in rats with renal disease treated with the angiotensin II receptor antagonist, eprosartan.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Gene Expression Regulation; Hypertension; Imidazoles; Kidney Diseases; Male; Nephrectomy; Proteinuria; Rats; Rats, Sprague-Dawley; Thiophenes | 2000 |
Direct effects of candesartan and eprosartan on human cloned potassium channels involved in cardiac repolarization.
Topics: Acrylates; Action Potentials; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cation Transport Proteins; Cell Line; CHO Cells; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart Conduction System; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Kv1.5 Potassium Channel; Mice; Papillary Muscles; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Shal Potassium Channels; Tetrazoles; Thiophenes; Trans-Activators; Transcriptional Regulator ERG | 2001 |
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2001 |
[Stress-induced hypertension. The work site--a cardiovascular risk].
Topics: Acrylates; Antihypertensive Agents; Circadian Rhythm; Humans; Hypertension; Imidazoles; Occupational Diseases; Stress, Psychological; Thiophenes; Workplace | 2001 |
Subcellular localization of angiotensin II in kidney and adrenal.
Topics: Acrylates; Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Imidazoles; Kidney; Male; Subcellular Fractions; Swine; Thiophenes; Tissue Distribution | 2001 |
Eprosartan reduces cardiac hypertrophy, protects heart and kidney, and prevents early mortality in severely hypertensive stroke-prone rats.
Topics: Acrylates; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hypertension; Imidazoles; Kidney; Magnetic Resonance Imaging; Male; Myocardium; Natriuresis; Organ Size; Peptide Fragments; Protein Precursors; Proteinuria; Rats; Rats, Inbred SHR; Stroke; Survival Rate; Thiophenes; Ventricular Remodeling | 2001 |
Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Ventricles; Imidazoles; Losartan; Male; Presynaptic Terminals; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Angiotensin; Thiophenes; Vasoconstrictor Agents; Ventricular Function | 2001 |
[Antihypertensive drug. Dual action lowers blood pressure more effectively].
Topics: Acrylates; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Thiophenes; Treatment Outcome | 2001 |
Central inhibition of AT1receptors by eprosartan--in vitro autoradiography in the brain.
Topics: Acrylates; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Blood Pressure; Blood-Brain Barrier; Body Weight; Brain; Heart Rate; Imidazoles; Male; Radiography; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Thiophenes | 2001 |
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Biochemistry; Biphenyl Compounds; Drug Design; Imidazoles; Irbesartan; Losartan; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Peptides, Cyclic; Rabbits; Structure-Activity Relationship; Tetrazoles; Thiophenes | 2001 |
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan.
Topics: Acrylates; Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dihydropyridines; Dose-Response Relationship, Drug; Imidazoles; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Thiophenes; Valine; Valsartan | 2001 |
Intrarenal angiotensin II: interstitial and cellular levels and site of production.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Imidazoles; Kidney; Swine; Thiophenes; Tissue Distribution | 2001 |
Brain angiotensinergic mediation of enhanced water consumption in lactating rats.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Atropine; Brain; Carbachol; Drinking; Female; Imidazoles; Injections, Intraventricular; Lactation; Muscarinic Agonists; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reference Values; Thiophenes | 2002 |
Application of capillary zone electrophoresis to the screening of some angiotensin II receptor antagonists.
Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Chemical Fractionation; Electrophoresis, Capillary; Imidazoles; Irbesartan; Losartan; Mathematical Computing; Molecular Structure; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2002 |
Structure elucidation and conformational properties of eprosartan, a non peptide angiotensin II AT1 antagonist.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Imidazoles; Models, Molecular; Molecular Conformation; Monte Carlo Method; Nuclear Magnetic Resonance, Biomolecular; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thermodynamics; Thiophenes | 2002 |
Effects of eprosartan versus hydrochlorothiazide on markers of vascular oxidation and inflammation and blood pressure (renin-angiotensin system antagonists, oxidation, and inflammation).
Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Inflammation; Lipoproteins, LDL; Male; Middle Aged; Muscle, Smooth, Vascular; Oxidation-Reduction; Receptors, Angiotensin; Renin-Angiotensin System; Thiophenes; Treatment Outcome; Vascular Cell Adhesion Molecule-1 | 2002 |
[Significance of pharmacological blockade of angiotensin II type I receptors for correction of abnormal 24-hour blood pressure profile depending on its variability in patients with arterial hypertension stage II].
Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Thiophenes | 2002 |
The angiotensin type 1 receptor antagonist, eprosartan, attenuates the progression of renal disease in spontaneously hypertensive stroke-prone rats with accelerated hypertension.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blotting, Western; Body Weight; Dietary Fats; Disease Progression; Extracellular Matrix; Fibrinolysin; Gene Expression Regulation; Heart Rate; Hypertension; Imidazoles; Kidney Diseases; Male; Organ Size; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serine Proteinase Inhibitors; Sodium Chloride, Dietary; Stroke; Thiophenes; Thrombosis | 2002 |
Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Presynaptic; Tetrazoles; Thiophenes | 2002 |
[Therapy of hypertension. Why the systolic value is decisive].
Topics: Acrylates; Antihypertensive Agents; Coronary Disease; Enalapril; Humans; Hypertension; Imidazoles; Risk Factors; Stroke; Systole; Thiophenes; Treatment Outcome | 2002 |
Drug points: Dysgeusia and burning mouth syndrome by eprosartan.
Topics: Acrylates; Antihypertensive Agents; Burning Mouth Syndrome; Dysgeusia; Female; Humans; Imidazoles; Middle Aged; Thiophenes | 2002 |
[Effect of eprosartan on left ventricular diastolic function and cerebral hemodynamics in patients with hypertension].
Topics: Acrylates; Adult; Antihypertensive Agents; Carotid Artery, Internal; Cerebrovascular Circulation; Diastole; Echocardiography; Female; Follow-Up Studies; Homeostasis; Humans; Hypertension; Imidazoles; Male; Middle Aged; Models, Cardiovascular; Thiophenes; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Ventricular Function, Left; Vertebral Artery | 2002 |
Eprosartan for the treatment of hypertension.
Topics: Acrylates; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Spain; Thiophenes | 2003 |
Effects of the AT1-receptor antagonist eprosartan on the progression of left ventricular dysfunction in dogs with heart failure.
Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Disease Progression; Dogs; Heart Failure; Imidazoles; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thiophenes; Ventricular Dysfunction, Left | 2003 |
Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification.
Topics: Acrylates; Algorithms; Angiotensin II; Biphenyl Compounds; Databases, Factual; Imidazoles; Lactones; Losartan; Models, Molecular; Molecular Conformation; Pyridines; Quantitative Structure-Activity Relationship; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfones; Tetrazoles; Thiophenes | 2003 |
Pre- and postsynaptic inhibitory potencies of the angiotensin AT1 receptor antagonists eprosartan and candesartan.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Presynaptic Terminals; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Vasoconstriction | 2003 |
Cardiology patient page. Angiotensin receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2003 |
[When the goal values are more than 20/10 mmHg distant. High blood pressure is to be forced down from two sides immediately].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzothiadiazines; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Sodium Chloride Symporter Inhibitors; Thiophenes; Time Factors | 2003 |
[Dosage equivalents of AT1-receptor antagonists available in Germany].
Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan | 2003 |
Renal damage is not improved by blockade of endothelin receptors in primary renin-dependent hypertension.
Topics: Acrylates; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Blood Pressure; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Glomerulosclerosis, Focal Segmental; Hypertension, Renal; Imidazoles; Kidney; Male; Metalloendopeptidases; Models, Cardiovascular; Nephritis, Interstitial; Organ Size; Osteopontin; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renin; Renin-Angiotensin System; RNA, Messenger; Sialoglycoproteins; Systole; Thiophenes | 2003 |
Impaired neuronal and vascular responses to angiotensin II in a rabbit congestive heart failure model.
Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Electric Stimulation; Heart Failure; Imidazoles; In Vitro Techniques; Male; Osmolar Concentration; Rabbits; Sympathetic Nervous System; Thiophenes | 2003 |
Re: Heusser et al: elevation of sympathetic activity by eprosartan in young male subjects.
Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Catecholamines; Heart Rate; Humans; Imidazoles; Male; Muscle, Skeletal; Norepinephrine; Stress, Psychological; Sympathetic Nervous System; Thiophenes | 2004 |
Eprosartan improves cardiac performance, reduces cardiac hypertrophy and mortality and downregulates myocardial monocyte chemoattractant protein-1 and inflammation in hypertensive heart disease.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Chemokine CCL2; Down-Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Immunohistochemistry; Macrophages; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; RNA, Messenger; Thiophenes; Ultrasonography; Vasculitis | 2004 |
Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation.
Topics: Acrylates; Aging; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Desipramine; Electrophysiology; Imidazoles; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Tetrodotoxin; Thiophenes; Vasoconstriction | 2004 |
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.
Topics: 3T3 Cells; Acrylates; Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Differentiation; Genes, Reporter; Imidazoles; Insulin Resistance; Irbesartan; Losartan; Luciferases; Mice; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; Telmisartan; Tetrazoles; Thiophenes; Transcription Factors; Transfection | 2004 |
[Anti-hypertensive effect of eprosartan in diabetic patients].
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diabetes Complications; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes | 2004 |
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Electrophoretic Mobility Shift Assay; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; Hydralazine; Hypertension; Imidazoles; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; NF-kappa B p50 Subunit; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiophenes; Transcription Factor RelA | 2004 |
[Elevation pressure in morning hours in patients with essential hypertension: effect therapy with eprosartan for leading stress tests].
Topics: Acrylates; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Data Interpretation, Statistical; Exercise Test; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes; Time Factors | 2004 |
Plasma vascular endothelial growth factor, angiopoietin-2, and soluble angiopoietin receptor tie-2 in diabetic retinopathy: effects of laser photocoagulation and angiotensin receptor blockade.
Topics: Acrylates; Angiopoietin-2; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Cross-Sectional Studies; Diabetic Retinopathy; Female; Humans; Imidazoles; Laser Coagulation; Male; Middle Aged; Receptor, TIE-2; Thiophenes; Vascular Endothelial Growth Factor A | 2004 |
Effect of eprosartan on pulse pressure and blood pressure components in patients with isolated systolic hypertension.
Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Body Mass Index; Cardiovascular Diseases; Cholesterol, LDL; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Thiophenes; Time Factors | 2004 |
Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Arteriovenous Fistula; Carboxypeptidases; Cardiomegaly; Disease Models, Animal; Heart Failure; Imidazoles; Male; Mineralocorticoid Receptor Antagonists; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Spironolactone; Thiophenes; Ventricular Remodeling | 2005 |
[Cerebral hemodynamics and endothelium function in patients with cerebrovascular pathology treated by teveten].
Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Brain; Brain Ischemia; Endothelium, Vascular; Female; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Thiophenes; Tomography, X-Ray Computed; Treatment Outcome | 2005 |
Analysis of recent papers in hypertension. An angiotensin receptor blocker is more effective than a calcium channel blocker in secondary stroke prevention.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Humans; Hypertension; Imidazoles; Nitrendipine; Randomized Controlled Trials as Topic; Stroke; Survival Rate; Thiophenes | 2005 |
Adrenal angiotensin: origin and site of generation.
Topics: Acrylates; Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Female; Imidazoles; Infusions, Intra-Arterial; Iodine Radioisotopes; Male; Models, Biological; Renin-Angiotensin System; Swine; Thiophenes | 2005 |
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?
Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome | 2005 |
Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity.
Topics: 3T3 Cells; Acrylates; Adipocytes; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Differentiation; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; Imidazoles; Irbesartan; Mice; Pioglitazone; PPAR gamma; Protein Conformation; Telmisartan; Tetrazoles; Thiazolidinediones; Thiophenes | 2005 |
Validation of a solid phase extraction-high performance liquid chromatographic method for the determination of eprosartan in human plasma.
Topics: Acrylates; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Stability; Humans; Imidazoles; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2006 |
[An AT-II blocker in patients with type II diabetes and arterial hypertension].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Diastole; Female; Humans; Hypertension; Imidazoles; Insulin; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Receptor, Angiotensin, Type 1; Thiophenes; Time Factors; Treatment Outcome; Ventricular Function, Left | 2006 |
Does the MOSES study provide sufficient evidence for Eprosartan against Nitrendipine?
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Humans; Imidazoles; Nitrendipine; Randomized Controlled Trials as Topic; Stroke; Thiophenes | 2006 |
New tools, old challenges: the emerging role of angiotensin receptor blockers in the treatment of the systolic hypertension epidemic.
Topics: Acrylates; Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Canada; Drug Utilization; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prognosis; Risk Assessment; Systole; Thiophenes; Treatment Outcome | 2004 |
The effect of treatment with eprosartan on pulse pressure: factors predicting response.
Topics: Acrylates; Administration, Oral; Aged; Aged, 80 and over; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Canada; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Maximum Tolerated Dose; Middle Aged; Predictive Value of Tests; Probability; Prospective Studies; Risk Assessment; Severity of Illness Index; Thiophenes; Treatment Outcome | 2004 |
Preventing cerebrovascular and cardiovascular events after stroke: eprosartan or nitrendipine?
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Follow-Up Studies; Humans; Imidazoles; Multicenter Studies as Topic; Nitrendipine; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Thiophenes; Treatment Outcome | 2006 |
[Not all antihypertensive agents protect equally well].
Topics: Acrylates; Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Follow-Up Studies; Humans; Hypertension; Imidazoles; Meta-Analysis as Topic; Nitrendipine; Primary Prevention; Risk Factors; Stroke; Thiophenes; Time Factors | 2006 |
[Stress-associated hypertension in the work place: results of the STARLET project].
Topics: Acrylates; Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Occupational Diseases; Prognosis; Prospective Studies; Stress, Physiological; Thiophenes; Workplace | 2006 |
Rationale, design and methods of the OSCAR study: observational study on cognitive function and systolic blood pressure reduction in hypertensive patients.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cognition; Cognition Disorders; Female; Humans; Hypertension; Imidazoles; Longitudinal Studies; Male; Middle Aged; Multicenter Studies as Topic; Neuropsychological Tests; Observation; Patient Selection; Receptor, Angiotensin, Type 1; Research Design; Thiophenes | 2007 |
Determination of eprosartan in human plasma and urine by LC/MS/MS.
Topics: Acrylates; Chromatography, Liquid; Humans; Imidazoles; Molecular Structure; Reproducibility of Results; Tandem Mass Spectrometry; Thiophenes | 2007 |
Small artery structure adapts to vasodilatation rather than to blood pressure during antihypertensive treatment.
Topics: Acrylates; Adult; Antihypertensive Agents; Arteries; Blood Pressure; Case-Control Studies; Echocardiography; Female; Humans; Imidazoles; Male; Middle Aged; Thiophenes; Vascular Resistance; Vasodilation; Ventricular Function, Left | 2007 |
Changes in fibrinolytic activity after angiotensin II receptor blockade in therapy-resistant hypertensive patients.
Topics: Acrylates; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Coagulation; Case-Control Studies; Drug Resistance; Endothelial Cells; Female; Fibrinolysis; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes | 2007 |
Introduction: The pharmacological profile of eprosartan--implications for cerebrovascular and cardiovascular risk reduction.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Cerebrovascular Disorders; Humans; Hypertension; Imidazoles; Middle Aged; Risk; Thiophenes | 2007 |
Selenosartans: novel selenophene analogues of milfasartan and eprosartan.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cricetinae; Female; Imidazoles; Molecular Structure; Organoselenium Compounds; Ovary; Receptor, Angiotensin, Type 1; Stereoisomerism; Structure-Activity Relationship; Sulfur; Thiophenes | 2008 |
Effectiveness of eprosartan in diabetic hypertensive patients.
Topics: Acrylates; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Diabetes Complications; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes; Time Factors; Treatment Outcome | 2008 |
Pharmacokinetics and urinary excretion of eprosartan in Chinese healthy volunteers of different gender.
Topics: Acrylates; Adult; Antihypertensive Agents; Area Under Curve; Electrocardiography; Female; Half-Life; Humans; Imidazoles; Male; Sex Characteristics; Thiophenes | 2007 |
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.
Topics: Acrylates; Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anilides; Arginine; Benzimidazoles; Benzoates; Cells, Cultured; Cellular Senescence; Down-Regulation; Endothelium, Vascular; Humans; Imidazoles; Nitric Oxide; Oxidative Stress; PPAR gamma; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Thiophenes; Up-Regulation | 2008 |
Separation and quantitation of several angiotensin II receptor antagonist drugs in human urine by a SPE-HPLC-DAD method.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Chromatography, High Pressure Liquid; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Solid Phase Extraction; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2008 |
[Effect of eprosartan on thrombocytes aggregative capacity in patients with arterial hypertension and metabolic syndrome].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Metabolic Syndrome; Middle Aged; Platelet Aggregation; Thiophenes; Treatment Outcome | 2008 |
Spectral and polarographic determination of eprosartan. Kinetic studies of the oxidation of eprosartan using a platinum electrode.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Cerium; Electrodes; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Oxidation-Reduction; Platinum; Polarography; Potassium Chloride; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Temperature; Thermodynamics; Thiophenes | 2008 |
Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growt
Topics: Acrylates; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalapril; Humans; Imidazoles; Indazoles; Lisinopril; Male; Mice; Mice, SCID; Neoplasms; Nifedipine; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Ramipril; Rats; Rats, Sprague-Dawley; Telmisartan; Thiophenes; Xenograft Model Antitumor Assays | 2009 |
Hemodynamic and cardiac effects of chronic eprosartan and moxonidine therapy in stroke-prone spontaneously hypertensive rats.
Topics: Acrylates; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Hypertension; Imidazoles; Male; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Inbred SHR; Stroke; Thiophenes; Ventricular Function, Left | 2009 |
Angiotensin receptor blockers and secondary stroke prevention: the MOSES study.
Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Ischemic Attack, Transient; Male; Nitrendipine; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thiophenes | 2009 |
Cost-utility analysis of eprosartan compared to enalapril in primary prevention and nitrendipine in secondary prevention in Europe--the HEALTH model.
Topics: Acrylates; Antihypertensive Agents; Cardiovascular Diseases; Cost-Benefit Analysis; Enalapril; Europe; Geography; Humans; Hypertension; Imidazoles; Male; Meta-Analysis as Topic; Middle Aged; Monte Carlo Method; Nitrendipine; Primary Prevention; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Stroke; Thiophenes | 2009 |
[The use of melaxen in combined therapy of arterial hypertension in subjects occupied in assembly line production].
Topics: Acrylates; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Central Nervous System Depressants; Circadian Rhythm; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Imidazoles; Industry; Melatonin; Middle Aged; Occupational Diseases; Occupational Exposure; Thiophenes; Treatment Outcome | 2009 |
Characterization of a novel impurity in bulk drug eprosartan by ESI/MS(n) and NMR.
Topics: Acrylates; Drug Contamination; Imidazoles; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Thiophenes | 2010 |
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes | 2010 |
Design and methodology of POWER, an open-label observation of the effect of primary care interventions on total cardiovascular risk in patients with hypertension.
Topics: Acrylates; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Canada; Cardiovascular Diseases; Humans; Hypertension; Imidazoles; Primary Health Care; Product Surveillance, Postmarketing; Research Design; Risk Factors; Thiophenes | 2013 |
Blood pressure responses to hypertension treatment and trends in cognitive function in patients with initially difficult-to-treat hypertension: a retrospective subgroup analysis of the Observational Study on Cognitive Function and SBP Reduction (OSCAR) st
Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cognition; Female; Humans; Hypertension; Imidazoles; Intention to Treat Analysis; Male; Middle Aged; Retrospective Studies; Thiophenes | 2012 |
Determination of eprosartan mesylate and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.
Topics: Acrylates; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Hydrochlorothiazide; Imidazoles; Tablets; Thiophenes | 2012 |
[The use of melatonin for correction of sleep disturbances in assembly-line shift workers with arterial hypertension].
Topics: Acrylates; Adult; Antihypertensive Agents; Circadian Clocks; Female; Humans; Hypertension; Imidazoles; Male; Melatonin; Middle Aged; Sleep Disorders, Circadian Rhythm; Thiophenes; Work Schedule Tolerance | 2012 |
Interstitial pneumonitis secondary to eprosartan.
Topics: Acrylates; Antihypertensive Agents; Humans; Imidazoles; Lung Diseases, Interstitial; Male; Middle Aged; Thiophenes | 2012 |
Effect of eprosartan-based therapy on systolic blood pressure and total cardiovascular risk in a large international population: preliminary report of the observational POWER study.
Topics: Acrylates; Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 2 Receptor Blockers; Blood Pressure; Cardiovascular Diseases; Chi-Square Distribution; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Product Surveillance, Postmarketing; Risk Factors; Statistics, Nonparametric; Systole; Thiophenes; Treatment Outcome | 2012 |
Association between eprosartan-based hypertension therapy and improvement in cognitive function score: long-term follow-up from the OSCAR observational study.
Topics: Acrylates; Aged; Aged, 80 and over; Blood Pressure; Cognition; Demography; Diastole; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neuropsychological Tests; Systole; Thiophenes | 2015 |
Effect of eprosartan-based antihypertensive therapy on coronary heart disease risk assessed by Framingham methodology in Canadian patients: results of the POWER survey.
Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Canada; Coronary Disease; Drug Therapy, Combination; Female; Health Care Surveys; Humans; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Risk Assessment; Risk Factors; Thiophenes; Time Factors; Treatment Outcome | 2014 |
Eprosartan improves cardiac function in swine working heart model of ischemia-reperfusion injury.
Topics: Acrylates; Animals; Blood Pressure; Disease Models, Animal; Heart Function Tests; Heart Ventricles; Imidazoles; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Swine; Thiophenes | 2014 |
Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biodegradation, Environmental; Biphenyl Compounds; Chromatography, Liquid; Environmental Monitoring; Germany; Imidazoles; Irbesartan; Mass Spectrometry; Molecular Structure; Rivers; Tetrazoles; Thiophenes; Valine; Valsartan; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2014 |
OATP and MRP2-mediated hepatic uptake and biliary excretion of eprosartan in rat and human.
Topics: Acrylates; Animals; Bile; Biological Transport; Dogs; HEK293 Cells; Hepatocytes; Humans; Imidazoles; In Vitro Techniques; Liver; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Rats; Rats, Wistar; Thiophenes | 2014 |
Quality by design: a systematic and rapid liquid chromatography and mass spectrometry method for eprosartan mesylate and its related impurities using a superficially porous particle column.
Topics: Acetonitriles; Acrylates; Ammonium Compounds; Chemistry, Pharmaceutical; Chromatography, Liquid; Chromatography, Reverse-Phase; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Imidazoles; Mass Spectrometry; Porosity; Reproducibility of Results; Software; Temperature; Thiophenes | 2014 |
Versatile reticular polyethylenimine derivative-mediated targeted drug and gene codelivery for tumor therapy.
Topics: Acrylates; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Atomic Force; Microvessels; Neovascularization, Pathologic; Polyethyleneimine; Thiophenes | 2014 |
Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages.
Topics: Acrylates; Angiotensin II; Animals; Anthracenes; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Imidazoles; Macrophages; Male; MAP Kinase Signaling System; Mice; Prostaglandin D2; Thiophenes; Up-Regulation | 2015 |
Ameliorative effect of eprosartan on high-fat diet/streptozotocin-induced early diabetic nephropathy in rats.
Topics: Acrylates; Angiotensin II; Animals; Blood Glucose; Catalase; Cholesterol; Collagen Type IV; Diabetic Nephropathies; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Glutathione; Imidazoles; Kidney; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; RNA, Messenger; Streptozocin; Thiophenes; Transforming Growth Factor beta1; Triglycerides | 2015 |
Celiac disease-like enteropathy due to antihypertensive therapy with the angiotensin-II receptor type 1 inhibitor eprosartan.
Topics: Acrylates; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Celiac Disease; Female; Humans; Hypertension; Imidazoles; Thiophenes | 2015 |
A self-assembled system for tumor-targeted co-delivery of drug and gene.
Topics: Acrylates; Chondroitin Sulfates; Drug Delivery Systems; Endocytosis; Gene Transfer Techniques; Hep G2 Cells; Humans; Imidazoles; Neoplasms; Plasmids; Polyethyleneimine; Thiophenes | 2015 |
Influence of initial angiotensin receptor blockers on treatment persistence in uncomplicated hypertension: A nation-wide population-based study.
Topics: Acrylates; Adult; Aged; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cohort Studies; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Medication Adherence; Middle Aged; Outcome Assessment, Health Care; Republic of Korea; Retrospective Studies; Risk Factors; Tetrazoles; Thiophenes; Valsartan | 2016 |
Acute eprosartan-induced intrarenal vasodilation in hypertensive humans is not influenced by dietary sodium intake or angiotensin II co-infusion.
Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Artery; Renal Circulation; Renin-Angiotensin System; Sodium; Sodium, Dietary; Thiophenes; Vasodilation | 2016 |
Formulation and statistical optimization of self-microemulsifying drug delivery system of eprosartan mesylate for improvement of oral bioavailability.
Topics: Acrylates; Administration, Oral; Animals; Biological Availability; Drug Delivery Systems; Drug Liberation; Emulsions; Excipients; Imidazoles; Male; Particle Size; Rats; Solubility; Thiophenes | 2016 |
[Psychological Characteristics of Patients With Stress-induced Arterial Hypertension: a Violation of the Regulation of Emotions as a Central Link of Pathogenesis].
Topics: Acrylates; Adult; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Determination; Emotions; Female; Humans; Hypertension; Imidazoles; Indapamide; Male; Middle Aged; Random Allocation; Stress, Psychological; Thiophenes; Treatment Outcome | 2016 |
The non-biphenyl-tetrazole angiotensin AT
Topics: Acrylates; Animals; Catalytic Domain; Dose-Response Relationship, Drug; Humans; Imidazoles; Ligands; Models, Molecular; Molecular Structure; Receptor, Angiotensin, Type 1; Structure-Activity Relationship; Thiophenes | 2018 |
Risk assessment and QbD based optimization of an Eprosartan mesylate nanosuspension: In-vitro characterization, PAMPA and in-vivo assessment.
Topics: Acrylates; Animals; Antihypertensive Agents; Drug Liberation; Imidazoles; Intestinal Mucosa; Male; Membranes, Artificial; Nanoparticles; Permeability; Rats, Wistar; Risk Assessment; Suspensions; Thiophenes | 2019 |
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan | 2020 |
Molecular and Genetic Bases of Inhibition of Tick-Borne Encephalitis Virus Replication by Eprosartan and Ribavirin.
Topics: Acrylates; Animals; Antiviral Agents; Cell Line; Cell Survival; Encephalitis Viruses, Tick-Borne; Epithelial Cells; Imidazoles; Kidney; Microbial Sensitivity Tests; Ribavirin; Swine; Thiophenes; Virus Replication | 2020 |
Formulation and design optimization of nano-transferosomes using pioglitazone and eprosartan mesylate for concomitant therapy against diabetes and hypertension.
Topics: Acrylates; Animals; Diabetes Mellitus, Type 2; Drug Carriers; Drug Delivery Systems; Humans; Hypertension; Imidazoles; Liposomes; Mesylates; Particle Size; Pioglitazone; Rats; Rats, Wistar; Thiophenes | 2021 |
Eprosartan: A closer insight into its neuroprotective activity in rats with focal cerebral ischemia-reperfusion injury.
Topics: Acrylates; Animals; Brain; Cerebrovascular Disorders; Imidazoles; Male; Nerve Tissue Proteins; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Thiophenes | 2021 |
Protective and therapeutic role of mango pulp and eprosartan drug and their anti-synergistic effects against thioacetamide-induced hepatotoxicity in male rats.
Topics: Acrylates; Animals; Antioxidants; Becaplermin; Chemical and Drug Induced Liver Injury; Fibrosis; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Imidazoles; Inflammation; Liver; Male; Mangifera; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Superoxide Dismutase; Thioacetamide; Thiophenes; Tumor Necrosis Factor-alpha | 2022 |
Formulation and characterization of eprosartan mesylate and β-cyclodextrin inclusion complex prepared by microwave technology.
Topics: Acrylates; beta-Cyclodextrins; Calorimetry, Differential Scanning; Imidazoles; Mesylates; Microwaves; Solubility; Spectroscopy, Fourier Transform Infrared; Technology; Thiophenes; X-Ray Diffraction | 2022 |
ATR1 Angiotensin II Receptor Reduces Hemoglobin S Polymerization, Phosphatidylserine Exposure, and Increases Deformability of Sickle Cell Disease Erythrocytes.
Topics: Acrylates; Anemia, Sickle Cell; Angiotensin II; Annexin A5; Erythrocytes; Hemoglobin, Sickle; Humans; Imidazoles; Losartan; Phosphatidylserines; Polymerization; Receptor, Angiotensin, Type 1; Thiophenes | 2022 |