thiophenes has been researched along with dorzolamide in 644 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.16) | 18.7374 |
1990's | 138 (21.43) | 18.2507 |
2000's | 296 (45.96) | 29.6817 |
2010's | 174 (27.02) | 24.3611 |
2020's | 35 (5.43) | 2.80 |
Authors | Studies |
---|---|
Constanzer, ML; Matuszewski, BK | 1 |
Carlson, LE; Ehinger, B; Eriksson, LO; Finnström, K; Holmin, C; Lippa, EA; Nilsson, SE; Nyman, K; Raitta, C; Ringvold, A | 1 |
Brunner-Ferber, E; Feicht, B; Hofmann, HM; Lippa, E; von Denffer, H | 1 |
Podos, SM; Serle, JB; Sugrue, MF; Wang, RF | 2 |
Podos, SM; Serle, JB | 1 |
Deasy, DA; Epstein, DL; Higginbotham, EJ; Holder, DJ; Kass, MA; Lippa, EA; Schuman, JS; Shaw, B; Skuta, GL; Weinreb, RN | 1 |
Baldwin, JJ; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF | 2 |
Miyamoto, S; Nakagami, T; Sawa, M; Yamazaki, Y | 1 |
Strahlman, E; Tipping, R; Vogel, R | 2 |
Palmberg, P | 1 |
Biollaz, J; Brunner-Ferber, F; Buclin, T; Gervasoni, JP; Jaquet, F; Magnin, JL; Munafo, A | 1 |
Serle, JB | 1 |
Miyamoto, S; Sawa, M; Yamazaki, Y | 2 |
Constanzer, ML; Kiganda, M; Matuszewski, BK | 1 |
Au, T; Constanzer, ML; Haddix, H; Matuszewski, BK; Woolf, EJ | 1 |
Cyrlin, M; Deasy, D; Esposito, D; Fazio, R; Lippa, EA; Panebianco, D; Shields, MB; Wilkerson, M; Yablonski, M | 1 |
Bosc, JM; Bron, AM; George, JL; Greve, EL; Gunning, FP; Lesure, P; Royer, JG; Sirbat, D | 1 |
Barber, BL; Santanello, NC | 1 |
Fineman, MS; Katz, LJ; Wilson, RP | 1 |
Ballantyne, C; Gray, TB; Simpson, AJ | 1 |
Hussar, DA | 1 |
Bayer, A; Erb, C; Ferrari, F; Maren, TH | 1 |
Clineschmidt, CM; Strahlman, ER; Tipping, R; Vogel, R | 1 |
Prell, R | 1 |
Barrish, A; Bruhin, PJ; Lin, JH; Wong, BK | 1 |
Geyer, O; Michaeli-Cohen, A | 1 |
Donohue, EK; Wilensky, JT | 1 |
Pfeiffer, N | 1 |
Sugrue, MF | 2 |
Kato, K; Sugai, N; Suzuki, K; Terashima, H | 1 |
Drake, MV | 1 |
Brubaker, RF; Larsson, LI; Maus, TL; McLaren, JW | 1 |
Arend, O; Arend, S; Harris, A; Martin, B | 1 |
Brinchman-Hansen, O; Heijl, A; Puustjärvi, T; Strahlman, E; Sverrisson, T; Tipping, R | 1 |
Conroy, CW; Levy, NS; Maren, TH; Wynns, GC | 1 |
Debon, C; Hariton, C; Percicot, CL; Schnell, CR | 1 |
Armegioiu, M; Gafencu, O; Ionita, M | 1 |
Balfour, JA; Wilde, MI | 1 |
Chavez, CM; Constanzer, ML; Matuszewski, BK | 1 |
Adelman, AE; Fiscella, RG; Fishman, GA; Grover, S | 1 |
Brooks, AM; Gillies, WE | 2 |
DuPont, J; Grunwald, JE; Mathur, S | 1 |
Allingham, RR; Choudhri, SA; Cox, T; Damji, KF; Herndon, LW; Shields, MB | 1 |
Bucci, MG; Centofanti, M; Manni, GL; Napoli, D | 1 |
Kohlhaas, M; Mammen, A; Richard, G | 1 |
Denk, PO; Knorr, M; Kriegerowski, M; Thiel, HJ | 1 |
Baltatzis, S; Kokolakis, SN; Ladas, ID; Panagiotidis, D; Theodossiadis, GP; Zafirakis, P | 1 |
Rocchi, A; Tingey, D | 1 |
Alm, A; Brubaker, R; Larsson, LI; Maus, T; Wayman, L | 1 |
Spencer, AF; Vernon, SA; Zambarakji, HJ | 1 |
Dick, B; Pillunat, LE; Schmidt, KG; von Rückmann, A | 1 |
Bourne, WM; Egan, CA; Hodge, DO; McLaren, JW | 1 |
Hong, PH; Krupin, T; Rosenberg, LF; Ruderman, JM; Tang, LQ | 1 |
Alm, A; Larsson, LI | 1 |
Izdebska, J | 1 |
Garrison, PM; Stewart, WC | 1 |
Ciocci, G; Landolfi, C; Marchetti, M; Milanese, C | 1 |
Elliott, WR; Harris, A; Harrison, J; Kavanagh, J; Sponsel, WE; Trigo, Y | 1 |
Barisani, T; Baumgartner, I; Biowski, R; Hommer, A; Kaminski, S; Koyuncu, D | 1 |
Bucci, MG; Centofanti, M; Manni, GL; Napoli, D; Parisi, V | 1 |
Longo, A; Ott, JP; Reibaldi, A; Russo, V; Uva, MG | 1 |
Rehůrek, J; Vancurová, J | 1 |
Lee, MS; Pasha, M; Weitzman, M | 1 |
Le Guilloux, JC | 1 |
Burnstein, Y; Higginbotham, EJ; Shelton, K | 1 |
Adamsons, I; Snyder, E; Strohmaier, K | 1 |
Brubaker, RF; Maus, TL; Vanlandingham, BD | 1 |
Adamsons, I; Clineschmidt, C; Laibovitz, R; Polis, A; Shedden, A; Taylor, J | 1 |
Adamsons, I; Ghosh, K; Horwitz, B; Khosrof, SA; Lass, JH; Laurence, JK | 1 |
Harris, A; Ugi, IA; Wegner, A | 1 |
Brubaker, RF; Vanlandigham, BD | 1 |
Gould, LF | 1 |
Gramer, E | 1 |
Silver, LH | 2 |
De Hoste, F; Detry-Morel, M | 1 |
Hustead, JD | 1 |
Brown, SV; Dennis, RF; Epstein, R; Konowal-Allen, A | 1 |
Durand-Cavagna, G; Plazonnet, B; Ponticello, GS; Sugrue, MF | 1 |
Adamsons, I; DuBiner, H; Snyder, E; Strohmaier, K | 2 |
Adamsons, IA; Boyle, JE; Ghosh, K; Gieser, DK | 2 |
Adamsons, IA; Clineschmidt, CM; Snyder, E; Williams, RD | 2 |
Briganti, F; Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT | 2 |
Lukaris, A; Roberts-Harry, TJ; Rogers, ZA; Sells, M; Zohdy, GA | 1 |
Brubaker, R; Dinslage, S; McLaren, J | 1 |
Aalto-Korte, K | 1 |
Brubaker, RF; Larsson, LI; Maus, TL; Wayman, LL | 1 |
Gerdtham, U; Jönsson, L; Kobelt, G; Krieglstein, GK | 1 |
Hoyng, PF; Rasker, MT | 1 |
Mermoud, A | 1 |
Adamsons, IA; Boyle, JE; Ostrov, CS; Polis, A | 1 |
Adamsons, IA; Hutzelmann, JE; Michael, AJ; Polis, AB | 1 |
Adamsons, I; Hutzelmann, J; Owens, S; Shedden, A; Vargas, E | 1 |
Pillunat, LE; Schmidt, KG; von Rückmann, A | 1 |
D'Andrea, A; D'Andrea, D; Ferreri, G | 1 |
Jörg, KM; Lachmann, C; Trinkmann, R | 1 |
Challa, P; Fanous, MM; Maren, TH | 1 |
Gebhardt, DO | 1 |
Güler, C; Kimal Arici, M; Topalkara, A | 1 |
Krupin, T; Talluto, DM; Wyse, TB | 1 |
Brucculeri, M; Hammel, T; Harris, A; Malinovsky, V; Martin, B | 1 |
Brown, SV; Cooke, DL; Dennis, RF; Epstein, RJ; Fraunfelder, FT; Konowal, A; Maguire, LJ; Morrison, JC; Verdier, DV | 1 |
Bauer, NJ; Hendrikse, F; March, WF; Motamedi, M; Webers, CA; Wicksted, JP | 1 |
Capeans, C; Gonzalez, F; Martinez, A; Perez, R; Sanchez-Salorio, M | 1 |
thoe Schwartzenberg, GW; Trope, GE | 1 |
Bron, A; Chapard, J; Creuzot-Garcher, C; D'Athis, P; Guerzider, V | 1 |
Banditt, P; Behrens-Baumann, W; Meyer, FP; Motschmann, M; Schmitz, K | 1 |
Bourne, WM | 1 |
Odberg, T | 1 |
Böhm, AG; Klemm, M; Köller, AU; Pillunat, LE; Richard, G; Schmidt, KG | 1 |
Arend, O; Chung, HS; Garrett, M; Harris, A; Kagemann, L; Martin, B | 1 |
Carlsen, J; Crandall, A; Durcan, J; Swartz, M; Zabriskie, N | 1 |
Chang, MR; Cheng, Q; Hartenbaum, D; Le, HH; Lee, DA | 1 |
Hartenbaum, D; Maloney, S; Orillac, R; Sharpe, E; Vacarelli, L; Wilson, H | 1 |
Carstens, E; Carstens, MI; Dessirier, JM; O'Mahony, M; Simons, CT | 1 |
Nass, JU; Nuskovski, M; Thieme, H; Wiederholt, M | 1 |
Bang, K; Dollerup, J; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Scherfig, E; Stefánsson, E | 1 |
Gormley, GJ; Hartenbaum, D; Liss, C; Maloney, S; Vaccarelli, L; Wilson, H | 1 |
Brubaker, RF; Ingram, CJ | 1 |
Adamsons, I; Gross, R; Pearson, J; Rusk, C; Sverrisson, T | 1 |
Hudgins, AC; Pruitt, CA; Sine, C; Stewart, WC | 1 |
Buckley, EG; Freedman, SF; Portellos, M | 1 |
Herbort, CP; Mermoud, A; Schnyder, CC; Tran, VT | 1 |
Findl, O; Georgopoulos, M; Menapace, R; Rainer, G; Schmetterer, K; Vass, C | 1 |
Adamsons, I | 1 |
Chakraborty, P; Tinu, AT; Villada, JR | 1 |
Karger, BL; Kautz, RA; Tim, RC | 1 |
Becker, R; Pillunat, LE; Schmidt, KG; von Rückmann, A | 1 |
Apatachioae, I; Chiselita, D; Poiata, I | 1 |
Damji, KF; Daneshvar, H; Gilberg, SM; Goela, A | 1 |
Emmerich, KH | 1 |
Barnes, GE; Chandler, ML; Dean, T; Li, B | 1 |
Sall, K | 1 |
Haddad, P | 1 |
Amyot, M; Boisjoly, HM; Charest, M; Giasson, CJ; Lesk, MR; Nguyen, TQ | 1 |
Brubaker, RF; Ingram, CJ; Nau, CB; Schoff, EO | 1 |
Arend, O; Cantor, L; Chung, HS; Harris, A; Kagemann, L; Martin, B | 1 |
Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS | 1 |
Bufidis, T; Hudgins, AG; Konstas, AG; Maltezos, A; Stewart, WC | 1 |
Nicolela, MT; Oga, E; Susanna, R | 1 |
Samuelson, TW; Simmons, ST | 1 |
Castiglioni, S; Chrambach, A; Eberini, I; Gianazza, E; Rondanini, A; Sirtori, CR; Vecchio, G | 1 |
O'Donoghue, EP | 1 |
Bucci, MG; Centofanti, M; Cocco, F; Gregori, D; Lorenzano, D; Manni, G | 1 |
Chopra, H; Day, DG; Holmes, KT; Kolker, AE; Konstas, AG; Lee, WH; Rieser, JC; Sharpe, ED; Stewart, WC | 1 |
Day, DG; Harbin, TS; Holmes, KT; Pastor, SA; Sharpe, ED; Stewart, JA; Stewart, WC | 1 |
Autelitano, A; Bottoli, A; Invernizzi, T; Orzalesi, N; Rossetti, L | 1 |
Brenner, S; Orion, E; Spivak, D | 1 |
Kobayashi, M; Naito, K | 1 |
Bang, K; Dollerup, J; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Stefánsson, E; Wiencke, AK | 1 |
Khan, MA; Sanders, R; Taguri, AH | 1 |
Bjarnadóttir, G; Gudmundsdóttir, E; Gudmundsdóttir, G; Loftsson, T; Masson, M; Sigurjónsdóttir, JF; Stefánsson, E | 1 |
Bergua, A; Horn, FK; Jünemann, A; Korth, M; Velten, IM | 1 |
Barnebey, H; Kwok, SY | 1 |
Findl, O; Georgopoulos, M; Heinze, G; Kiss, B; Menapace, R; Rainer, G | 1 |
Choudhri, S; Shields, MB; Wand, M | 1 |
Pek, H; Wilhelm, H | 1 |
Gagliuso, DJ; Podos, SM; Serle, JB; Wang, RF | 1 |
Gomez, ML; Honrubia, FM; Larrosa, JM; Pablo, L; Polo, V | 1 |
McClellan, K; Ormrod, D | 1 |
Herkel, U; Pfeiffer, N | 2 |
Rehůrek, J; Spicarová, R; Vancurová, J | 1 |
Aurilia, P; Boles Carenini, B; Durante, A; Guarnaccia, G | 1 |
Brogliatti, B; Cipullo, D; Rolle, T; Vizzeri, GM | 1 |
Danese, M; Martin, XD | 1 |
Hoshaw-Woodard, S; Robbin, TE; Schmall, ML; Wilkie, DA; Willis, AM | 1 |
Casini, A; Ilies, MA; Menabuoni, L; Mincione, F; Scozzafava, A; Supuran, CT | 1 |
Simmons, ST | 1 |
Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G | 1 |
Anielska, E; Czechowicz-Janicka, K; Dyczkowska, A; Orlewska, E; Tobota, Z | 1 |
Gelatt, KN; MacKay, EO | 1 |
Cawrse, MA; Hendrix, DV; Ward, DA | 1 |
Bernd, AS; Böhm, AG; Pillunat, LE; Richard, G; Schmidt, KG | 1 |
Higaki, Y; Kawashima, M; Shimada, M | 1 |
Asensio Sánchez, VM | 1 |
Friren, B; Michaud, JE | 1 |
Krueger, RR; Nagy, ZZ; Süveges, I; Szabó, A | 1 |
Potocký, M | 1 |
Andreanos, D; Dimitrakoulias, N; Kandarakis, A; Mylopoulos, N; Petounis, A | 1 |
Chang, B; James, T; Mitra, M | 1 |
Cole, C; Garzozi, H; Harris, A; Jonescu-Cuypers, CP; Kagemann, L; Martin, B; Nowacki, EA | 1 |
Jurkowska-Dudzińska, J; Kawa, P; Zagórski, Z; Zarnowski, T | 1 |
Berdondini, RM; Mancuso, G | 1 |
Dick, HB; Krummenauer, F; Schwenn, O; Xia, N | 1 |
Flammer, J; Gherghel, D; Gugleta, K; Orgül, S | 1 |
Holdiness, MR | 1 |
Gressnerová, S; Oláh, Z; Veselá, A; Veselovský, J | 4 |
Chang, HW; Tsai, JC | 1 |
Bebawy, LI | 1 |
Beehne, K; Delaney, YM; Gee, B; Mossa, F; Powell, S; Salmon, JF | 1 |
Banditt, P; Martens-Lobenhoffer, J | 1 |
Erk, N | 3 |
Bucolo, C; Maltese, A | 1 |
Diehl, KA; Robbin, TE; Willis, AM | 1 |
Bergstrand, IC; Harris, A; Heijl, A | 1 |
Balado Vázquez, P; Conejero Arroyo, J; Domingo Gordo, B; Rodríguez Ausín, P; Urcelay Segura, JL | 1 |
Azuara-Blanco, A; Bain, M; Bateman, DN; Clark, R; Forrest, J | 1 |
Cabarga Del Nozal, C; García Campos, JM; Luque Aranda, R; Silva Silva, G; Vázquez Salvi, A | 1 |
El Sherbini, M; Flammer, J; Gekkieva, M; Haefliger, IO | 1 |
Easthope, SE; Perry, CM | 1 |
Martone, JF; Mead, A; O'Connor, DJ | 1 |
Avila, MY; Civan, MM; Seidler, RW; Stone, RA | 1 |
Dios Castro, E; Maquet Dusart, JA | 1 |
Halper, LK; Hartenbaum, D; Johnson-Pratt, L; Polis, A; Stewart, WC | 1 |
Larsson, LI; Mishima, HK; Orzalesi, N; Rossetti, L; Takamatsu, M | 1 |
Bron, AM; Emmerich, KH | 1 |
Adamsons, I; Cunha-Vaz, J; Miglior, S; Pfeiffer, N; Torri, V; Zeyen, T | 4 |
Bron, A | 1 |
Bonanno, JA; Ong, A; Srinivas, SP; Zhai, CB | 1 |
Phelan, P | 1 |
Bottoli, A; Fogagnolo, P; Fumagalli, E; Invernizzi, T; Orzalesi, N; Rossetti, I | 1 |
Bucci, MG; Centofanti, M; Gregori, D; Manni, G; Migliardj, R; Oddone, F; Scipioni, M | 1 |
Davani, S; Delbosc, B; Kantelip, JP; Royer, B | 1 |
Bernays, ME; Hampson, EC; Smith, RI | 1 |
Cantor, LB | 1 |
Ermis, SS; Inan, UU; Ozturk, F | 2 |
Honrubia, FM; Larsson, LI; Spiegel, D | 1 |
Lanzl, I; Nagel, E; Vilser, W | 2 |
Berdeaux, G; Berto, P; Gouveia Pinto, C; Le Pen, C; Rouland, JF | 1 |
Day, DG; Leech, J; Schacknow, PN; Sharpe, ED; Stewart, JA; Stewart, WC; Wand, M | 1 |
Konstas, AG; Kozobolis, VP; Leech, J; Stewart, WC; Tersis, I | 1 |
Funk, RW; Gersch, U; Reber, F | 1 |
Boyle, DR; Cassel, DA; DeLucca, PT; Fletcher, CA; Greff, LJ; Johnson-Pratt, LR; Kolodny, AH; Polis, AB; Sall, KN; Skobieranda, F | 1 |
Recker, K | 1 |
Amaral, M; Arieta, C; Crosta, C; de Carvalho Moreira Filho, D; José, N; Matuda, E | 1 |
Leech, JN; Stewart, JA; Stewart, WC | 1 |
Bottoli, A; Fogagnolo, P; Fumagalli, E; Orzalesi, N; Rossetti, L | 1 |
Brignoli, R; Mermoud, A; Ravinet, E | 1 |
Hommer, A; Kapik, B; Shams, N | 1 |
Pajic, B | 1 |
Drexler, W; Findl, O; Heinzl, H; Kiss, B; Petternel, V; Wirtitsch, MG | 1 |
Dziezyc, J; Rainbow, ME | 1 |
Ciulla, TA; Garzozi, HJ; Harris, A; Kagemann, L; Piper, HC; Pratt, LM; Rechtman, E | 1 |
Cantor, LB; Hoop, J; Katz, LJ; Lin, JC; Samuel, F; Spaeth, GL | 1 |
Bacharach, J; Delgado, MF; Iwach, AG | 1 |
Fong, JC; Hong, SJ; Wang, HZ; Wu, KY | 1 |
Flammer, J; Gugleta, K; Orgül, S | 1 |
Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzalkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska, A | 1 |
Houliara, D; Konstas, AG; Papapanos, P; Stewart, WC; Tersis, I | 1 |
Ahmed, MA; Geh, V; Morris, S; Nischal, KK; Sahi, S | 1 |
Cimino, L; Gandolfi, SA; Mora, P; Orzalesi, N; Rossetti, L; Tardini, M | 1 |
Mozaffari, E; Reardon, G; Schwartz, GF | 1 |
Nesher, R; Ticho, U | 1 |
Arend, O; Harris, A; Remky, A; Wolter, P | 1 |
Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G; Sacu, S; Schmid, K | 1 |
Akaishi, T; Hara, H; Kuwayama, Y; Matsugi, T; Miyawaki, N; Shimazaki, A | 1 |
Chen, YF; Hung, PT; Yang, CH | 1 |
Bauer, P; Eichler, H; Findl, O; Groke, I; Schmetterer, L; Sycha, T; Vass, C | 1 |
Casini, A; Menabuoni, L; Mincione, F; Scozzafava, A; Starnotti, M; Supuran, CT | 1 |
Assalian, A; Castilloux, AM; Houde, M; LeLorier, J; Tingey, D | 1 |
Amano, S; Inoue, K; Inoue, Y; Kato, S; Okugawa, K; Oshika, T; Tomita, G | 1 |
Pandey, RM; Ratan, SK; Sodhi, PK | 1 |
Bang, K; Eysteinsson, T; Josefsson, A; Sigurdsson, SB | 1 |
Araie, M; Azuma, I; Hamanaka, T; Kitazawa, Y; Origasa, H; Shirato, S; Tomita, G | 1 |
Bang, K; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Pedersen, DB; Stefánsson, E | 2 |
Larsson, LI; Tsukamoto, H | 1 |
Amoako-Mensah, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Georgopoulos, M; Kircher, K; Rainer, G; Schmetterer, L; Vass, C; Wally, B | 1 |
Day, DG; Holmes, KT; Jenkins, JN; Stewart, JA; Stewart, WC | 1 |
Aoyama, Y; Hada, N; Inoue, J; Kobayashi, S; Oka, M; Takeda, T; Takehana, M; Ueno, S | 1 |
Feldman, RM; Sheu, WP; Shin, DH | 1 |
Aoyama, Y; Hashimoto, M; Motoki, M | 1 |
Dutta, B; Lones, R; Mullins, RJ | 1 |
Cassel, DA; DeLucca, PT; Hustad, CM; Kolodny, AH; Skobieranda, F; Solish, AM | 1 |
Fechtner, RD; Henry, C; Hughes, B; Lee, DA; Terry, S; Whitson, JT | 1 |
Gabelt, BT; Kaufman, PL; Kiland, JA | 1 |
Camras, CB; Toris, CB; Yablonski, ME; Zhan, GL | 1 |
Strutton, DR; Walt, JG | 1 |
Arias Puente, A; Carrasco Font, C; García Sáenz, MC; Villarejo Díaz-Maroto, I | 1 |
Benz, MS; Eifrig, CW; Escalona-Benz, EM; Moore, JK; Murray, TG; Schiffman, JC; Yoder, DM | 1 |
Akman, A; Akova, YA; Cetinkaya, A; Ertan, A | 1 |
Attanasio, A; Baglio, S; Bartorelli, L; Quatrana, M | 1 |
Beischel, CJ; Day, DG; Rhodes, JS; Sharpe, ED; Stewart, JA; Stewart, WC | 1 |
Christodoulakis, E; Konstas, AG; Kozobolis, VP; Lallos, N; Stewart, JA; Stewart, WC | 1 |
Sheu, WP; Susanna, R; Sussana, R | 1 |
Brown, SV; Epstein, RJ; Konowal, A | 1 |
McKay, IC; Montgomery, DM; Morris, D; Osborne, SA | 1 |
Berke, S; Du, LT; Ehrenhaus, M; Francis, BA; Minckler, DS | 1 |
Călugăru, D; Călugăru, M | 2 |
Ardelean, C; Nenciu, A; Stefan, C | 1 |
Gupta, R; Vernon, SA | 1 |
Bishara, S; Blumenthal, EZ; Gallily, R; Goldberg, S | 1 |
Ignat, F | 1 |
Alver, A; Keha, EE; Ovali, E; Uçar, F | 1 |
Langenbucher, A; Mardin, CY; Martus, P; Schlötzer-Schrehardt, U; Viestenz, A | 1 |
Buys, YM; Faingold, D; Flanagan, J; Guan, K; Hudson, C; Rawji, M; Trope, GE | 1 |
Kazakevich, YV; LoBrutto, R; Pan, L; Thompson, R | 1 |
Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzałkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska-Zmijewska, A | 1 |
Harris, A; Janulevicienë, I; Kagemann, L; McCranor, L; Siesky, B | 1 |
Eysteinsson, T; Gudmundsdóttir, E; Loftsson, T; Sigurdsson, HH; Stefánsson, E; Thorsteinsdóttir, M | 1 |
Bayer, A; Oeverhaus, U; Skrotzki, FE; Stewart, WC; Weiler, W | 1 |
Aşagidag, A; Ermiş, SS; Inan, UU; Oztürk, F; Yaman, S | 1 |
de la Cuadra Oyanguren, J; Linares Mata, T; Pardo Sánchez, J | 1 |
Bang, K; Eysteinsson, T; Kiilgaard, JF; Koch Jensen, P; la Cour, M; Pedersen, DB; Stefánsson, E; Wiencke, AK | 1 |
Abe, H; Fukuchi, T; Hashimoto, K; Matsuda, H; Seki, M; Tanaka, T; Togano, T; Ueda, J | 1 |
Arend, O; Remky, A; Sponsel, WE; Weber, A | 1 |
Georgiadis, N; Karabatsas, CH; Konstas, AG; Kotsimpou, A; Lallos, N; Stewart, JA; Stewart, WC | 1 |
Galambos, P; Klemm, M; Matthiessen, ET; Reuss, J; Richard, G; Wagenfeld, L; Wiermann, A; Zeitz, O | 1 |
Ikeda, H; Matsuyama, S; Mishima, HK; Noma, H; Tsukamoto, H | 1 |
Klemm, M; Matthiessen, ET; Richard, G; Vilchez, SE; Zeitz, O | 1 |
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Abramson, J; Allbaugh, RA; Alter, H; Amano, C; Amicarella, F; Ara, N; Armengou, L; Asano, N; Bai, SJ; Ben-Shlomo, G; Benoit, E; Bhatnagar, A; Bolli, R; Boulanger, F; Brohawn, P; Brouchkov, A; Buckner, JD; Bukh, J; Buysschaert, C; Carlson, M; Cesarini, C; Cheng, L; Chipinda, I; Cogle, CR; Cooke, JP; Costa, DB; Damotte, D; Das, S; Däster, S; De Chatterjee, A; De Leon, J; Delko, T; Devi, P; Dieu-Nosjean, MC; Droeser, RA; Duarte, T; Ebert, RF; Ecker, AH; Ellis, SG; Eppenberger-Castori, S; Farhoudi, A; Folch, E; Foster, DW; Frasson, D; Fujishima, F; Gangadharan, SP; Gao, W; Germain, C; Glanemann, M; Governa, V; Grant, MB; Hammond, SA; Han, CX; Haspel, RL; He, X; Heberer, M; Henry, TD; Hettick, J; Higgs, BW; Hirt, C; Huang, Y; Huberman, MS; Iezzi, G; Iijima, K; Imatani, A; Ishikawa, N; Izumi, H; Jeon, CO; Jessell, L; Joblin, C; Johnstone, BH; Jose-Cunilleras, E; Joseph, LJ; Jung, WY; Kanazawa, I; Kang, N; Kawaguchi, K; Kawai, K; Kent, MS; Kettelhack, C; Khurshid, SS; Kinney, KA; Kitajima, S; Knockaert, S; Koike, T; Kubo, M; Kuroda, E; Lai, D; Laschke, MW; Lassiter, T; Le, X; Lee, HJ; Lehmann, K; Li, D; Li, F; Li, J; Li, XX; Liu, J; Liu, Y; Liu, YY; Liu, Z; Ma, J; Maejima, R; Majid, A; Makielski, KM; Man, S; Mao, M; Margesin, R; Martincigh, BS; Maruyama, R; Mele, V; Mendez, TL; Menger, MD; Meuleman, P; Miyake, H; Morakinyo, MK; Morimoto, Y; Moussavian, MR; Moyé, L; Myojo, T; Nebiker, CA; Nejad, SA; Nestor, B; Noguchi, T; Oertli, D; Onaka, T; Orozco, A; Oyabu, T; Padovan, E; Pepine, CJ; Perin, EC; Pilleri, P; Prentoe, J; Qiu, P; Rangachari, D; Resende, M; Ríos, J; Robles-Martinez, L; Safarzadeh, MA; Sahraei, E; Salehi, MM; Sasaki, T; Sayre, SL; Schlachtenberger, G; Schutt, RC; Sconocchia, G; Sebastian, Y; Shimada, M; Shimosegawa, T; Siegel, JA; Siegel, PD; Simari, RD; Simoyi, RH; Song, YH; Soysal, SD; Spagnoli, GC; Strongin, R; Sugimoto, T; Tanaka, KI; Tang, XD; Tao, Y; Taylor, DA; Terracciano, L; Thiessen, CE; Tofflemire, KL; Tomonaga, T; Tornillo, L; Traverse, JH; Uno, K; Valge-Archer, V; Validire, P; VanderLaan, PA; Velázquez Moctezuma, R; Verhoye, L; Viu, J; von Heesen, M; von Holzen, U; Wagner, M; Wang, FY; Wang, R; Weixler, B; Whitley, RD; Willerson, JT; Windsor, LC; Wise, E; Wu, FZ; Wu, ZY; Yamamoto, K; Yano, S; Yao, Y; Yatera, K; Yin, Q; Yoshiura, Y; Zhang, DC; Zhang, L; Zhao, DX; Zhou, Y; Zhu, W; Zhu, X; Zierold, C; Zvolensky, MJ | 1 |
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Fridley, C; Fu, J; Gedam, M; Hanes, J; Hu, Q; Liu, W; Liu, Y; Pitha, I; Quigley, HA; Sun, F | 1 |
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Choy, YB; Huh, BK; Kim, SN; Kim, YK; Lee, SH; Park, CG; Park, KH; Park, MA; Won, H | 1 |
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Biagioli, E; Galli, F; Katsanos, A; Longo, A; Oddone, F; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN | 1 |
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Boevé, MH; de Gee, R; Djajadiningrat-Laanen, SC; Elders, DJ; Koele, LE; Slenter, IJM; Vermeer, LW | 1 |
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Jung, JH; Kim, SI; Lee, JE; Lee, SM; Shin, J | 1 |
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54 review(s) available for thiophenes and dorzolamide
Article | Year |
---|---|
A topical carbonic anhydrase inhibitor finally arrives.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1995 |
Pharmacological advances in the treatment of glaucoma.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Ethacrynic Acid; Glaucoma; Humans; Latanoprost; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1994 |
[Topical carbonic anhydrase inhibitors in the treatment of glaucoma].
Topics: Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1996 |
[Topical carbonic anhydrase inhibitors for glaucoma].
Topics: Acetazolamide; Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Methazolamide; Sulfonamides; Thiophenes | 1996 |
Trusopt, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1996 |
[Local carbonic anhydrase inhibitor dorzolamide: development and properties].
Topics: Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Structure-Activity Relationship; Sulfonamides; Thiophenes | 1996 |
The preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dogs; Drug Combinations; Drug Evaluation, Preclinical; Glaucoma; Intraocular Pressure; Macaca; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Timolol | 1996 |
New medical therapies for glaucoma.
Topics: Adrenergic alpha-Agonists; Carbonic Anhydrase Inhibitors; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 1996 |
Dorzolamide. A review of its pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension.
Topics: Absorption; Aging; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Controlled Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quality of Life; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Tissue Distribution | 1997 |
[Trusopt--a new form of drug for treating glaucoma].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Therapy, Combination; Glaucoma; Intraocular Pressure; Pilocarpine; Sulfonamides; Thiophenes | 1997 |
Beta-blocker-induced complications and the patient with glaucoma. Newer treatments to help reduce systemic adverse events.
Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Cardiovascular System; Central Nervous System; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Neurosecretory Systems; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Respiratory System; Sulfonamides; Thiophenes | 1998 |
Dorzolamide, a 40-year wait. From an oral to a topical carbonic anhydrase inhibitor for the treatment of glaucoma.
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sulfonamides; Thiophenes | 1998 |
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
Topics: Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Combination; Female; Glaucoma; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1998 |
Topical carbonic anhydrase inhibitors.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Forecasting; Glaucoma; Humans; In Vitro Techniques; Sulfonamides; Thiazines; Thiophenes | 2000 |
[Pharmacological profiles of the potent carbonic anhydrase inhibitor dorzolamide hydrochloride, a topical antiglaucoma agent].
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes | 2000 |
Topical dorzolamide 2%/timolol 0.5%: a review of its use in the treatment of open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Timolol; Vision, Ocular | 2000 |
Update on topical carbonic anhydrase inhibitors.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Eye; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes | 2001 |
Dorzolamide-induced immune thrombocytopenia: a case report and literature review.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Male; Platelet Count; Sulfonamides; Thiophenes; Thrombocytopenia | 2001 |
Contact dermatitis to topical drugs for glaucoma.
Topics: Dermatitis, Allergic Contact; Epinephrine; Glaucoma; Humans; Ophthalmic Solutions; Pilocarpine; Sulfonamides; Thiophenes; Timolol | 2001 |
Clinical pharmacokinetics of dorzolamide.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ciliary Body; Cornea; Erythrocytes; Glaucoma; Humans; Intraocular Pressure; Isoenzymes; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2002 |
Advances in topical glaucoma therapy.
Topics: Administration, Topical; Animals; Cat Diseases; Cats; Clonidine; Dog Diseases; Dogs; Glaucoma; Humans; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes | 2002 |
Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctival Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2002 |
The effect of latanoprost on circadian intraocular pressure.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2002 |
Latanoprost versus combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
[Comparison of latanoprost monotherapy with timolol-dorzolamide combination in patients with open-angle glaucoma or ocular hypertension].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Reappraising first-line treatment in glaucoma management.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Dinoprost; Drug Therapy, Combination; Glaucoma; Humans; Latanoprost; Lipids; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Travoprost | 2002 |
An update on bimatoprost in glaucoma therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amides; Antihypertensive Agents; Benzimidazoles; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Omeprazole; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2002 |
Four years later: a clinical update on latanoprost.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Interventions for normal tension glaucoma.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Vincamine | 2003 |
[Timolol topical ophthalmic combination].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Intraocular pressure-lowering effect of adding dorzolamide or latanoprost to timolol: a meta-analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Databases, Factual; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2007 |
X-linked retinoschisis: an update.
Topics: Adult; Age of Onset; Animals; Biopolymers; Cell Adhesion; Child; Child, Preschool; Chromosomes, Human, X; Diagnosis, Differential; Diagnostic Techniques, Ophthalmological; Disease Models, Animal; Disease Progression; Eye Proteins; Female; Genes, X-Linked; Genetic Carrier Screening; Genetic Counseling; Genetic Therapy; Humans; Infant; Macular Degeneration; Male; Mice; Phenotype; Prevalence; Protein Structure, Tertiary; Retinoschisis; Sulfonamides; Thiophenes | 2007 |
Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2007 |
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2008 |
The efficacy and harm of prostaglandin analogues for IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: a systematic review.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Female; Glaucoma; Humans; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Treatment Outcome | 2008 |
[Fixed combinations of glaucoma medications].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2008 |
Efficacy and tolerability of latanoprost compared to dorzolamide combined with timolol in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized, controlled trials.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2009 |
[Neuroprotection in glaucoma].
Topics: Betaxolol; Brimonidine Tartrate; Disease Progression; Glaucoma; Guanidines; Humans; Memantine; Neuroprotective Agents; Quinoxalines; Sulfonamides; Thiophenes | 2007 |
Meta-analysis of medical intervention for normal tension glaucoma.
Topics: Aged; Amides; Antihypertensive Agents; Betaxolol; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Travoprost | 2009 |
Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Databases, Factual; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Optic Nerve Diseases; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol | 2009 |
Topical carbonic anhydrase inhibitors and visual function in glaucoma and ocular hypertension.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ocular Hypertension; Sulfonamides; Thiazines; Thiophenes; Visual Fields | 2010 |
Topical drug delivery to the eye: dorzolamide.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Aqueous Humor; Biological Availability; Carbonic Anhydrase Inhibitors; Drug Delivery Systems; Glaucoma; Humans; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2012 |
Meta-analysis of α2-adrenergic agonists versus carbonic anhydrase inhibitors as adjunctive therapy.
Topics: Adrenergic alpha-2 Receptor Agonists; Carbonic Anhydrase Inhibitors; Databases, Factual; Female; Humans; Intraocular Pressure; Male; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes | 2012 |
[Mode of action, clinical profile and relevance of carbonic anhydrase inhibitors in glaucoma therapy].
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Ciliary Body; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes | 2013 |
Oxidative stress and potential applications of free radical scavengers in glaucoma.
Topics: Animals; Antioxidants; Apoptosis; DNA; Free Radical Scavengers; Ginkgo biloba; Glaucoma; Humans; Lipid Peroxidation; Oxidative Stress; Protein Carbonylation; Resveratrol; Stilbenes; Sulfonamides; Thiophenes | 2013 |
Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Drug Tolerance; Female; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2013 |
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal; Anticonvulsants; Antineoplastic Agents; Benzodiazepines; Carbonic Anhydrase Inhibitors; Celecoxib; Clinical Trials as Topic; Contraindications; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fructose; Humans; Isoxazoles; Methazolamide; Phenobarbital; Sulfanilamide; Sulfanilamides; Sulfonamides; Sulfonic Acids; Thiazines; Thiophenes; Topiramate; Zonisamide | 2016 |
Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye.
Topics: Administration, Ophthalmic; Administration, Topical; Animals; Cyclodextrins; Dexamethasone; Drug Delivery Systems; Excipients; Humans; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes | 2017 |
Efficacy of carbonic anhydrase inhibitors in management of cystoid macular edema in retinitis pigmentosa: A meta-analysis.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Female; Humans; Macular Edema; Male; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Treatment Outcome; Visual Acuity | 2017 |
Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature.
Topics: Adenine; Administration, Topical; Aged; Anterior Chamber; Antihypertensive Agents; Antineoplastic Agents; Brimonidine Tartrate; Cataract Extraction; Humans; Intraocular Pressure; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Phacoemulsification; Piperidines; Prednisolone; Pyrazoles; Pyrimidines; Sulfonamides; Syndrome; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2018 |
The efficacy of the fixed combination of latanoprost and timolol versus other fixed combinations for primary open-angle glaucoma and ocular hypertension: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2020 |
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2021 |
Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Animals; Antineoplastic Agents; Antioxidants; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Indoles; Isatin; Molecular Docking Simulation; Organoselenium Compounds; Oxadiazoles; Protein Binding; Protein Isoforms; Pyrimidines; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes; Urea | 2021 |
237 trial(s) available for thiophenes and dorzolamide
Article | Year |
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Dose response and duration of action of dorzolamide, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes | 1992 |
[MK-507 (L-671 152): local tolerance and effectiveness of a new local carbonic anhydrase inhibitor in healthy probands].
Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cellulose; Double-Blind Method; Humans; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1991 |
MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes | 1991 |
A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International Dorzolamide Study Group.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1995 |
Whole-blood pharmacokinetics and metabolic effects of the topical carbonic anhydrase inhibitor dorzolamide.
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Half-Life; Humans; Male; Prospective Studies; Sulfonamides; Thiophenes | 1995 |
Four-week safety and efficacy study of dorzolamide, a novel, active topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Count; Cornea; Double-Blind Method; Drug Tolerance; Endothelium, Corneal; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes | 1993 |
Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Delivery Systems; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Polysaccharides, Bacterial; Sulfonamides; Thiophenes | 1993 |
Relating spontaneous adverse experience reports to scores on a questionnaire querying tolerability.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1995 |
A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 1996 |
A controlled clinical trial of dorzolamide: a single-centre subset of a multicentre study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol | 1996 |
Comparison of dorzolamide and acetazolamide as suppressors of aqueous humor flow in humans.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Fluorescein; Fluoresceins; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1997 |
Effects of topical dorzolamide on retinal and retrobulbar hemodynamics.
Topics: Administration, Topical; Antihypertensive Agents; Blood Flow Velocity; Double-Blind Method; Fluorescein Angiography; Fundus Oculi; Humans; Image Processing, Computer-Assisted; Intraocular Pressure; Lasers; Ophthalmic Solutions; Ophthalmoscopes; Orbit; Reference Values; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 1996 |
A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosa.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Visual Acuity | 1997 |
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
Effects of dorzolamide hydrochloride 2% on the retinal circulation.
Topics: Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fundus Oculi; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes | 1997 |
Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cornea; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 1997 |
Comparative effects of intraocular pressure between systemic and topical carbonic anhydrase inhibitors: a clinical masked, cross-over study.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Aging; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Eye Color; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1997 |
[Change in corneal sensitivity after topical dorzolamide administration. A comparative study].
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Antihypertensive Agents; Cornea; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Pain Threshold; Procaine; Sulfonamides; Thiophenes | 1997 |
Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
Economic evaluation of dorzolamide vs. pilocarpine for primary open-angle glaucoma.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Costs and Cost Analysis; Glaucoma, Open-Angle; Humans; Models, Economic; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Sulfonamides; Thiophenes | 1997 |
Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans.
Topics: Adrenergic beta-Antagonists; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
Effect of dorzolamide on corneal endothelial function in normal human eyes.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Fluorescein; Fluorophotometry; Humans; Hypoxia; Intraocular Pressure; Microscopy; Middle Aged; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes | 1998 |
Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 1998 |
Aqueous humor flow in human eyes treated with dorzolamide and different doses of acetazolamide.
Topics: Acetazolamide; Administration, Oral; Adult; Aqueous Humor; Bicarbonates; Carbonic Anhydrase Inhibitors; Contrast Media; Double-Blind Method; Drug Therapy, Combination; Eye; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiophenes | 1998 |
Dorzolamide hydrochloride and visual function in normal eyes.
Topics: Adult; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercapnia; Hypocapnia; Intraocular Pressure; Male; Ophthalmic Solutions; Pilot Projects; Sulfonamides; Thiophenes; Visual Field Tests; Visual Fields | 1997 |
Hypotensive effects of dorzolamide eyewash in maximal therapy glaucoma patients: a comparative study with oral acetazolamide.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields | 1998 |
The effect of dorzolamide on aqueous humor dynamics in normal human subjects during sleep.
Topics: Administration, Topical; Adult; Anterior Eye Segment; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sleep; Sulfonamides; Thiophenes | 1998 |
The efficacy and safety of dorzolamide as adjunctive therapy to timolol maleate gellan solution in patients with elevated intraocular pressure. Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gels; Humans; Male; Middle Aged; Ocular Hypertension; Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
A double-masked, randomized, 1-year study comparing the corneal effects of dorzolamide, timolol, and betaxolol. Dorzolamide Corneal Effects Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Cell Count; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
Combined effect of dorzolamide and latanoprost on the rate of aqueous humor flow.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Uvea | 1998 |
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 1998 |
Central corneal thickness.
Topics: Carbonic Anhydrase Inhibitors; Cornea; Glaucoma; Humans; Ocular Hypertension; Sulfonamides; Thiophenes | 1998 |
A trial of dorzolamide for glaucoma.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Administration Routes; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Care; Prospective Studies; Sulfonamides; Thiophenes | 1998 |
Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol.
Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Synergism; Female; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 1998 |
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Topical carbonic anhydrase inhibition increases ocular pulse amplitude in high tension primary open angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Cataract; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Placebos; Prospective Studies; Pulsatile Flow; Sulfonamides; Thiophenes | 1998 |
Clinical use of a topical carbonic anhydrase inhibitor in patients affected by chronic simple glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
[Postoperative behavior of intraocular pressure after posterior Nd:YAG laser capsulotomy--critical evaluation in preventive administration of local carbonic anhydrase II inhibitor dorzolamide hydrochloride (Trusopt)].
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Premedication; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
Additive effect of latanoprost and dorzolamide in patients with elevated intraocular pressure.
Topics: Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
Dorzolamide effect on ocular blood flow.
Topics: Aged; Carbonic Anhydrase Inhibitors; Eye; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Reference Values; Regional Blood Flow; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Effect of topical dorzolamide on optic nerve head blood flow.
Topics: Administration, Topical; Adult; Capillaries; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors | 1999 |
Dorzolamide, visual function and ocular hemodynamics in normal-tension glaucoma.
Topics: Blood Pressure; Carbonic Anhydrase Inhibitors; Double-Blind Method; Glaucoma; Heart Rate; Humans; Ocular Physiological Phenomena; Regional Blood Flow; Sulfonamides; Thiophenes; Visual Acuity | 1999 |
A randomized study of dorzolamide in the prevention of elevated intraocular pressure after anterior segment laser surgery. Dorzolamide Laser Study Group.
Topics: Anterior Eye Segment; Carbonic Anhydrase Inhibitors; Double-Blind Method; Humans; Intraocular Pressure; Laser Therapy; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Sulfonamides; Thiophenes | 1999 |
Comparison of dorzolamide and pilocarpine as adjunctive therapy in patients with open-angle glaucoma and ocular hypertension.
Topics: Adjuvants, Pharmaceutic; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Parasympathomimetics; Patient Dropouts; Pilocarpine; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 1999 |
Effect of brinzolamide and dorzolamide on aqueous humor flow in human eyes.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Thiophenes | 1999 |
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1999 |
Daily cost of newer glaucoma agents.
Topics: Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Gels; Glaucoma; Humans; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Solutions; Sulfonamides; Thiophenes; Timolol | 1999 |
Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Cross-Over Studies; Female; Glaucoma; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes | 1998 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 1999 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
Effect of dorzolamide and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 1999 |
[Ocular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol | 1999 |
[The ocular hypotensive effect of the combination of latanoprost with dorzolamide].
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 1999 |
Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension.A 3-month randomised study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
Ocular comfort of brinzolamide 1.0% ophthalmic suspension compared with dorzolamide 2.0% ophthalmic solution: results from two multicenter comfort studies. Brinzolamide Comfort Study Group.
Topics: Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open-angle glaucoma or ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Dorzolamide and corneal recovery from edema in patients with glaucoma or ocular hypertension.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cell Count; Contact Lenses; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Tonometry, Ocular | 2000 |
Comparison of the efficacy of betaxolol-brinzolamide and timolol-dorzolamide as suppressors of aqueous humor flow in human subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aqueous Humor; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
A comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2000 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
Twenty-four hour control of intraocular pressure with dorzolamide and timolol maleate in exfoliation and primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2000 |
Additive effect of latanoprost to the combination of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
Comparison of brimonidine with latanoprost in the adjunctive treatment of glaucoma. ALPHAGAN/XALATAN Study Group.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
A comparison of latanoprost and dorzolamide in patients with glaucoma and ocular hypertension: a 3 month, randomised study. Ireland Latanoprost Study Group.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Circadian Rhythm; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2000 |
Comparative acute effects of brimonidine 0.2% versus dorzolamide 2% combined with beta-blockers in glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2000 |
Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocular pressure.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension.
Topics: Carbonic Anhydrase Inhibitors; Cyclodextrins; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Methazolamide; Ocular Hypertension; Ophthalmic Solutions; Pharmaceutical Vehicles; Sulfonamides; Thiophenes | 2000 |
Patients' acceptance of a switch from dorzolamide to brinzolamide for the treatment of glaucoma in a clinical practice setting.
Topics: Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Patient Satisfaction; Prospective Studies; Sulfonamides; Thiazines; Thiophenes | 2000 |
Randomised fellow eye comparison of the effectiveness of dorzolamide and apraclonidine on intraocular pressure following phacoemulsification cataract surgery.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Female; Humans; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Prospective Studies; Sulfonamides; Thiophenes | 2000 |
A comparison of dorzolamide-timolol combination versus the concomitant drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2000 |
[Effect of dorzolamide on accommodation and pupillary reaction?].
Topics: Accommodation, Ocular; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Male; Ophthalmic Solutions; Reflex, Pupillary; Sulfonamides; Thiophenes | 2000 |
Latanoprost versus combined therapy with timolol plus dorzolamide: IOP-lowering effect in open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
The hypotensive efficacy of dorzolamide HCL-timolol maleate 0.50% vs concomitant use of the two drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Therapeutic Equivalency; Thiophenes; Timolol | 2000 |
Comparison of the efficacy on intraocular pressure and retinal blood flow of a beta-blocker (timolol maleate) against the fixed association of a topical carbonic anhydrase (dorzolamide) and a beta-blocker (timolol maleate).
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2000 |
Hypotensive efficacy in primary open-angle glaucoma and ocular hypertension: latanoprost in monotherapy vs timolol and dorzolamide in association.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2000 |
Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Down-Regulation; Female; Glaucoma; Humans; Immunologic Factors; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes | 2001 |
Intraindividual comparison of the effects of a fixed dorzolamide-timolol combination and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
[Ocular hemodynamics and visual field in glaucoma treated with dorzolamide].
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Eye; Female; Follow-Up Studies; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Visual Fields | 2001 |
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2001 |
Treatment of intraocular pressure elevation after photorefractive keratectomy.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorometholone; Glucocorticoids; Humans; Intraocular Pressure; Lasers, Excimer; Male; Ocular Hypertension; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2001 |
Comparison of the additive intraocular pressure-lowering effect of latanoprost and dorzolamide when added to timolol in patients with open-angle glaucoma or ocular hypertension: a randomized, open-label, multicenter study in Greece.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Effect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Indocyanine Green; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography; Visual Acuity | 2001 |
[Clinical evaluation of isopropyl unoprostone (Rescula), in the adjunctive treatment of primary open angle glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2001 |
[Prevention of early postoperative increase in intraocular pressure after phacoemulsification. Comparison of different antiglaucoma drugs].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Polysaccharides, Bacterial; Postoperative Care; Postoperative Complications; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2001 |
Retrobulbar blood flow in glaucoma patients with nocturnal over-dipping in systemic blood pressure.
Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Sectional Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Artery; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2001 |
Dorzolamide and ocular blood flow in previously untreated glaucoma patients: a controlled double-masked study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Double-Blind Method; Eye; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2002 |
[Study on hypotensive effect of latanoprost vs timolol-dorzolamide association].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
The European glaucoma prevention study design and baseline description of the participants.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Research Design; Safety; Sulfonamides; Thiophenes; Visual Acuity; Visual Field Tests; Visual Fields | 2002 |
Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2002 |
The short-term IOP-lowering effect of brimonidine 0.2% and dorzolomide 2% combination in primary open-angle glaucoma.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes | 2002 |
A comparison of the effects on intraocular pressure of latanoprost 0.005% and the fixed combination of dorzolamide 2% and timolol 0.5% in patients with open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2002 |
Cost-minimisation study of dorzolamide versus brinzolamide in the treatment of ocular hypertension and primary open-angle glaucoma: in four European countries.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Economics, Pharmaceutical; Europe; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2003 |
The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Patient Satisfaction; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2003 |
Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2003 |
Dorzolamide X apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clonidine; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Time Factors | 2002 |
Acute and chronic ocular symptoms of dorzolamide 2% compared with placebo.
Topics: Acute Disease; Adult; Carbonic Anhydrase Inhibitors; Chronic Disease; Double-Blind Method; Eye Diseases; Female; Humans; Male; Ophthalmic Solutions; Pain; Pain Measurement; Sulfonamides; Thiophenes; Time Factors | 2003 |
The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2003 |
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2003 |
Short-term effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.
Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Corneal Diseases; Cross-Over Studies; Double-Blind Method; Endothelium, Corneal; Female; Humans; Hypertrophy; Interferometry; Light; Male; Middle Aged; Sulfonamides; Thiophenes | 2003 |
The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration.
Topics: Aged; Antihypertensive Agents; Choroid; Coloring Agents; Double-Blind Method; Female; Fluorescein Angiography; Humans; Indocyanine Green; Macular Degeneration; Male; Middle Aged; Retinal Vessels; Sulfonamides; Thiophenes | 2003 |
The effect of topical glaucoma medications evaluated by perimetry.
Topics: Administration, Topical; Antihypertensive Agents; Betaxolol; Clonidine; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Levobunolol; Prospective Studies; Sulfonamides; Thiophenes; Visual Field Tests | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Replacing maximum-tolerated medications with latanoprost versus adding latanoprost to maximum-tolerated medications: a two-center randomized prospective trial.
Topics: Adrenergic beta-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Retreatment; Single-Blind Method; Sulfonamides; Thiophenes | 2003 |
Evaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patients.
Topics: Adrenergic beta-Antagonists; Arteries; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ophthalmoscopy; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Veins | 2003 |
Effect of a fixed dorzolamide-timolol combination on intraocular pressure after small-incision cataract surgery with Viscoat.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Time Factors; Timolol | 2003 |
A six-week, parallel, randomized, double-blind study comparing the efficacy and safety of the 0.5% timolol/2.0% MK-507 combination b.i.d. to the concomitant administration of 0.5% timolol b.i.d. and 2.0% MK-507 b.i.d.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Sulfonamides; Thiophenes; Timolol | 2003 |
Efficacy and safety of brimonidine, dorzolamide and latanoprost as adjunctive therapy in primary open angle glaucoma.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Child; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2003 |
The efficacy and safety of dose escalation of dorzolamide used in combination with other topical antiglaucoma agents.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Irritants; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins; Sulfonamides; Thiophenes; Time Factors | 2003 |
Aqueous humor flow in normal human eyes treated with brimonidine and dorzolamide, alone and in combination.
Topics: Administration, Topical; Adult; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Cornea; Double-Blind Method; Drug Therapy, Combination; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes | 2004 |
Short-term ocular tolerability of dorzolamide 2% and brinzolamide 1% vs placebo in primary open-angle glaucoma and ocular hypertension subjects.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Sulfonamides; Thiazines; Thiophenes | 2004 |
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Comparison of the safety and efficacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2004 |
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
[Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2004 |
Immediate postoperative use of a topical agent to prevent intraocular pressure elevation after pars plana vitrectomy with gas tamponade.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Fluorocarbons; Humans; Intraocular Pressure; Male; Middle Aged; Postoperative Complications; Postoperative Period; Prospective Studies; Retinal Detachment; Retinal Perforations; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2004 |
Comparison of additional intraocular pressure-lowering effects of latanoprost vs brimonidine in primary open-angle glaucoma patients with intraocular pressure uncontrolled by timolol-dorzolamide combination.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes | 2004 |
Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%.
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparison of latanoprost with fixed-combination dorzolamide and timolol in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label, parallel-group, multicenter study in Latin America.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparing the fixed combination dorzolamide-timolol (Cosopt) to concomitant administration of 2% dorzolamide (Trusopt) and 0.5% timolol -- a randomized controlled trial and a replacement study.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2004 |
[Structural and immunohistochemical changes of conjunctiva induced by topical glaucoma medication].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzalkonium Compounds; Betaxolol; Carbonic Anhydrase Inhibitors; Cloprostenol; Conjunctiva; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Immunohistochemistry; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Travoprost | 2004 |
[Impact of prostaglandin-F(2alpha)-analogues and carbonic anhydrase inhibitors on central corneal thickness -- a cross-sectional study on 403 eyes].
Topics: Acetazolamide; Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Collagen; Cornea; Corneal Topography; Cross-Sectional Studies; Dinoprost; Drug Therapy, Combination; Extracellular Matrix; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Travoprost; Ultrasonography | 2004 |
Assessment of retinal hemodynamics with the Canon laser blood flowmeter after a single dose of 2% dorzolamide hydrochloride eyedrops.
Topics: Administration, Topical; Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes | 2004 |
[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients].
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
A comparison of the effects of dorzolamide/timolol fixed combination versus latanoprost on intraocular pressure and pulsatile ocular blood flow in primary open-angle glaucoma patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Cross-Over Studies; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler | 2004 |
Two-year follow-up of latanoprost 0.005% monotherapy after changing from previous glaucoma therapies.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2004 |
Comparison of the efficacy and safety of dorzolamide 2% when added to brimonidine 0.2% or timolol maleate 0.5% in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Results of the European Glaucoma Prevention Study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality Assurance, Health Care; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2005 |
Topical dorzolamide increases pericentral visual function in age-related maculopathy: pilot study findings with short-wavelength automated perimetry.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Macular Degeneration; Male; Pilot Projects; Prospective Studies; Sulfonamides; Thiophenes; Visual Acuity; Visual Field Tests; Visual Fields | 2005 |
24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Safety; Sulfonamides; Thiophenes; Visual Acuity | 2005 |
Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428].
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Ciliary Arteries; Cloprostenol; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Latanoprost; Lipids; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Artery; Single-Blind Method; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2005 |
Dorzolamide influences the autoregulation of major retinal vessels caused by artificial intraocular pressure elevation in patients with POAG: a clinical study.
Topics: Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Muscle, Smooth, Vascular; Ocular Hypertension; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation | 2005 |
The efficacy and safety of topical brinzolamide and dorzolamide when added to the combination therapy of latanoprost and a beta-blocker in patients with glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Instillation, Drug; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Treatment Outcome | 2005 |
Efficacy of the dorzolamide/timolol fixed combination versus latanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies.
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
A randomized trial assessing dorzolamide in patients with glaucoma who are younger than 6 years.
Topics: Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2005 |
The efficacy and ocular discomfort of substituting brinzolamide for dorzolamide in combination therapy with latanoprost, timolol, and dorzolamide.
Topics: Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision, Ocular | 2005 |
Comparison of latanoprost monotherapy and combined therapy of 0.5% timolol and 1% dorzolamide in chronic primary angle-closure glaucoma (CACG) in Japanese patients.
Topics: Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Female; Glaucoma, Angle-Closure; Humans; Instillation, Drug; Intraocular Pressure; Japan; Latanoprost; Male; Ophthalmic Solutions; Patient Compliance; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2005 |
A comparison of the effects of 0.005% latanoprost and fixed combination dorzolamide/timolol on retrobulbar haemodynamics in previously untreated glaucoma patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
Comparative analysis of the efficacy and safety of latanoprost, travoprost and the fixed combination timolol-dorzolamide; a prospective, randomized, masked, cross-over design study.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2005 |
Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa.
Topics: Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Diagnostic Techniques, Ophthalmological; Female; Humans; Macular Edema; Male; Middle Aged; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2006 |
Comparative analysis of the effects of brimonidine and dorzolamide on ocular blood flow velocity in patients with newly diagnosed primary open-angle glaucoma.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Brimonidine Tartrate; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome; Ultrasonography, Doppler, Color | 2006 |
The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Ciliary Arteries; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Artery; Pilocarpine; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2006 |
Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Circadian Rhythm; Diastole; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Perfusion; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2006 |
Additive effect of dorzolamide or carteolol to latanoprost in primary open-angle glaucoma: a prospective randomized crossover trial.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carteolol; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 2006 |
Comparison of the efficacy and safety of travoprost with a fixed-combination of dorzolamide and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Travoprost | 2006 |
Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study.
Topics: Antihypertensive Agents; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prognosis; Proportional Hazards Models; Risk Factors; Sulfonamides; Thiophenes; Visual Acuity | 2007 |
A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2006 |
Central corneal thickness in the European Glaucoma Prevention Study.
Topics: Adult; Age Factors; Aged; Cornea; Diabetes Complications; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sex Factors; Sulfonamides; Thiophenes; Ultrasonography | 2007 |
Circadian intraocular pressure control with dorzolamide versus timolol maleate add-on treatments in primary open-angle glaucoma patients using latanoprost.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2007 |
Continued use of dorzolamide for the treatment of cystoid macular oedema in patients with retinitis pigmentosa.
Topics: Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Follow-Up Studies; Fovea Centralis; Humans; Macular Edema; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity | 2007 |
Comparison of the ocular hypotensive effects of bimatoprost and timolol-dorzolamide combination in patients with elevated intraocular pressure: a 6-month study.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2007 |
Retrobulbar haemodynamic effects of the latanoprost/timolol and the dorzolamide/timolol fixed combinations in newly diagnosed glaucoma patients.
Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2007 |
Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.
Topics: Aged; Brimonidine Tartrate; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2007 |
A comparison of latanoprost monotherapy with a combination therapy of timolol/dorzolamide in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Eye Color; Eyelashes; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Prostaglandins F, Synthetic; Pruritus; Sulfonamides; Thiophenes; Timolol | 2006 |
Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Confidence Intervals; Cornea; Diuretics; Double-Blind Method; Europe; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Prevalence; Proportional Hazards Models; Retinal Hemorrhage; Retrospective Studies; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Treatment Outcome | 2007 |
Ocular comfort of combination glaucoma therapies: brimonidine 0.2%/timolol 0.5% compared with dorzolamide 2%/timolol 0.5%.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Patient Compliance; Patient Satisfaction; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2007 |
Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Capsulorhexis; Cataract; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Prosthesis Design; Sulfonamides; Thiophenes; Timolol | 2007 |
Effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.
Topics: Aged; Aged, 80 and over; Body Weights and Measures; Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Corneal Diseases; Corneal Edema; Cross-Over Studies; Double-Blind Method; Endothelium, Corneal; Female; Humans; Interferometry; Intraocular Pressure; Light; Male; Middle Aged; Sulfonamides; Thiophenes; Tonometry, Ocular | 2007 |
Success rates for switching to dorzolamide/timolol fixed combination in timolol responders who are insufficiently controlled by latanoprost monotherapy.
Topics: Aged; Antihypertensive Agents; Cohort Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Satisfaction; Prospective Studies; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Treatment Outcome | 2008 |
[Additive therapy with carboanhydrase inhibitors for open angle glaucoma previously treated with timolol 0.5% drops].
Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Thiophenes; Timolol | 2007 |
Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Postoperative Care; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
The effects of dorzolamide 2% and dorzolamide/timolol fixed combination on retinal and optic nerve head blood flow in primary open-angle glaucoma patients.
Topics: Aged; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2008 |
Efficacy of the latanoprost versus timolol/dorzolamide combination therapy in patients with primary open angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2008 |
Effectiveness and safety of dorzolamide-timolol alone or combined with latanoprost in open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Canada; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
A comparative study of the effects of brinzolamide and dorzolamide on retinal oxygen saturation and ocular microcirculation in patients with primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Oxygen; Pilot Projects; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes; Visual Acuity | 2008 |
Comparison of twice-daily and three-times-daily dosing of dorzolamide in ocular hypertension and primary open-angle glaucoma patients treated with latanoprost.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2008 |
Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diastole; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
A comparison of dorzolamide/timolol-fixed combination versus bimatoprost in patients with open-angle glaucoma who are poorly controlled on latanoprost.
Topics: Aged; Aged, 80 and over; Amides; Bimatoprost; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2008 |
24-hour control of intraocular pressure with 2% dorzolamide/0.5% timolol fixed-combination ophthalmic solution in open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2008 |
Effects of dorzolamide 2% added to timolol maleate 0.5% on intraocular pressure, retrobulbar blood flow, and the progression of visual field damage in patients with primary open-angle glaucoma: a single-center, 4-year, open-label study.
Topics: Aged; Antihypertensive Agents; Disease Progression; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Fields | 2008 |
Prolongation of activity of single intravitreal bevacizumab by adjuvant topical aqueous depressant (Timolol-Dorzolamide).
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aqueous Humor; Bevacizumab; Diabetic Retinopathy; Drug Synergism; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Macular Edema; Male; Middle Aged; Retinal Vein Occlusion; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity; Vitreous Body | 2009 |
Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2008 |
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2008 |
Efficacy and safety of latanoprost in eyes with uveitic glaucoma.
Topics: Adult; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Uveitis, Anterior; Uveitis, Intermediate; Visual Acuity | 2009 |
A comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2009 |
Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Single-Blind Method; Sulfonamides; Thiazines; Thiophenes; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Comparison of effects of topical levobunolol to a combination of timolol-dorzolamide on intraocular pressure and pulse rate of healthy dogs.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dogs; Drug Combinations; Female; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol | 2009 |
Ocular blood flow and oxygen delivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Oximetry; Oxygen; Regional Blood Flow; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2010 |
Predictors for visual field progression and the effects of treatment with dorzolamide 2% or brinzolamide 1% each added to timolol 0.5% in primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Disease Progression; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Proportional Hazards Models; Prospective Studies; Retinal Artery; Risk Factors; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler, Color; Vision Disorders; Visual Fields | 2010 |
Effect of dorzolamide and timolol on ocular pressure: blood flow relationship in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Interferometry; Intraocular Pressure; Laser-Doppler Flowmetry; Lasers; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2010 |
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2010 |
Fixed-combination brimonidine/timolol as adjunctive therapy to a prostaglandin analog: a 3-month, open-label, replacement study in glaucoma patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Hypersensitivity; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.
Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2010 |
The additive effect of dorzolamide hydrochloride (Trusopt) and a morning dose of bimatoprost (Lumigan) on intraocular pressure and retrobulbar blood flow in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Cloprostenol; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Orbit; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes | 2010 |
Comparison of the effects of dorzolamide/timolol and latanoprost/timolol fixed combinations upon intraocular pressure and progression of visual field damage in primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Disease Progression; Dosage Forms; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Fields | 2010 |
Effects of topical 0.5% levobunolol alone or in association with 2% dorzolamide compared with a fixed combination of 0.5% timolol and 2% dorzolamide on intraocular pressure and heart rate in dogs without glaucoma.
Topics: Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Dogs; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol | 2010 |
Intraocular pressure and ocular hemodynamics in patients with primary open-angle glaucoma treated with the combination of morning dosing of bimatoprost and dorzolamide hydrochloride.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Blood Pressure; Circadian Rhythm; Cloprostenol; Drug Administration Schedule; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Retinal Artery; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Ultrasonography, Doppler, Color | 2011 |
[Comparative study of the pressure lowering efficacy and variations in the ocular pulse amplitude between fixed combinations of dorzolamide/timolol and brinzolamide/timolol].
Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Pulse; Sulfonamides; Thiazines; Thiophenes; Timolol; Young Adult | 2011 |
From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study.
Topics: Aged; Antihypertensive Agents; Diagnostic Techniques, Ophthalmological; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiazines; Thiophenes; Timolol | 2011 |
[Double-masked, phase III comparative study of the combination ophthalmic solution of the 1% dorzolamide hydrochloride/0.5% timolol maleate (MK-0507A) in patients with glaucoma and ocular hypertension].
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2011 |
Pharmacodynamic equivalence study of two preparations of eye drops containing dorzolamide and timolol in healthy volunteers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Eye Movements; Female; Fundus Oculi; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pupil; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Visual Acuity; Young Adult | 2011 |
Diurnal intraocular pressure efficacy of the timolol-brimonidine fixed combination and the timolol-dorzolamide fixed combination as a first choice therapy in patients with pseudoexfoliation glaucoma.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Single-Blind Method; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Acuity | 2011 |
Comparison of dorzolamide/timolol and latanoprost/timolol fixed combinations on diurnal intraocular pressure control in primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Optic Disk; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2012 |
Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cornea; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sphygmomanometers; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography | 2012 |
Fixed topical combinations in glaucomatous patients and ocular discomfort.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Benzalkonium Compounds; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Preservatives, Pharmaceutical; Prospective Studies; Single-Blind Method; Sulfonamides; Suspensions; Thiazines; Thiophenes; Time Factors; Timolol | 2012 |
Three-month evaluation of dorzolamide hydrochloride/timolol maleate fixed-combination eye drops versus the separate use of both drugs.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
The Heidelberg retina tomograph ancillary study to the European glaucoma prevention study: study design and baseline factors.
Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmoscopy; Optic Disk; Optic Nerve Diseases; Research Design; Sulfonamides; Thiophenes; Tomography; Tonometry, Ocular; Visual Acuity; Visual Fields | 2013 |
Comparison of dorzolamide/timolol versus brimonidine/timolol fixed combination therapy in the management of steroid-induced ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Diabetic Retinopathy; Drug Combinations; Female; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Triamcinolone Acetonide | 2015 |
γ-Cyclodextrin nanoparticle eye drops with dorzolamide: effect on intraocular pressure in man.
Topics: Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Delivery Systems; Female; gamma-Cyclodextrins; Humans; Intraocular Pressure; Male; Nanoparticles; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Visual Acuity | 2014 |
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluid.
Topics: Biological Availability; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Dexamethasone; Double-Blind Method; Female; gamma-Cyclodextrins; Glucocorticoids; Humans; Male; Nanoparticles; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Suspensions; Tandem Mass Spectrometry; Tears; Thiophenes; Tissue Distribution | 2014 |
Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes.
Topics: Adult; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Logistic Models; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2014 |
Effect of topical aqueous suppression on intraocular gas duration after pure perfluoropropane injection in nonvitrectomized eyes with retinal detachment.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cryotherapy; Drug Combinations; Endotamponade; Fluorocarbons; Humans; Injections, Intraocular; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinal Detachment; Scleral Buckling; Sulfonamides; Thiophenes; Time Factors; Timolol; Vitrectomy | 2014 |
Comparison of topical dorzolamide and ketorolac treatment for cystoid macular edema in retinitis pigmentosa and Usher's syndrome.
Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Female; Fovea Centralis; Humans; Ketorolac Tromethamine; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Usher Syndromes; Visual Acuity; Visual Field Tests; Visual Fields; Young Adult | 2015 |
Effect of topical ophthalmic dorzolamide(2%)-timolol(0.5%) solution and ointment on intraocular pressure in normal horses.
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Ointments; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Latanoprost and Dorzolamide for the Treatment of Pediatric Glaucoma: The Glaucoma Italian Pediatric Study (Gipsy), Design and Baseline Characteristics.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 2016 |
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Effects of perioperative topical dorzolamide hydrochloride-timolol maleate administration on incidence and severity of postoperative ocular hypertension in dogs undergoing cataract extraction by phacoemulsification.
Topics: Animals; Antihypertensive Agents; Cataract Extraction; Dog Diseases; Dogs; Drug Combinations; Ocular Hypertension; Perioperative Care; Postoperative Complications; Sulfonamides; Thiophenes; Timolol | 2016 |
Dorzolamide nanoliposome as a long action ophthalmic delivery system in open angle glaucoma and ocular hypertension patients.
Topics: Antihypertensive Agents; Cornea; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Liposomes; Nanoparticles; Ocular Hypertension; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes; Time Factors | 2018 |
The Glaucoma Italian Pediatric Study (GIPSy): 1-Year Results.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prognosis; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2017 |
The Glaucoma Italian Pediatric Study (GIPSy): 3-Year Results.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2018 |
The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
Topics: Animals; Cats; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Sulfonamides; Thiazines; Thiophenes; Timolol | 2020 |
Dilatation of Retinal Arterioles Induced by Topical Dorzolamide for One Week Is Impaired in Patients with Type 1 Diabetes and Mild Retinopathy.
Topics: Administration, Ophthalmic; Adult; Arterioles; Blood Pressure; Carbonic Anhydrase Inhibitors; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Homeostasis; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation | 2020 |
Combination of Intravitreal Bevacizumab and Topical Dorzolamide versus Intravitreal Bevacizumab Alone for Diabetic Macular Edema: A Randomized Contralateral Clinical Trial.
Topics: Administration, Topical; Aged; Bevacizumab; Diabetic Retinopathy; Female; Humans; Intravitreal Injections; Iran; Macular Edema; Male; Middle Aged; Sulfonamides; Thiophenes | 2020 |
The Glaucoma Italian Pediatric Study (GIPSy): The Long-term Effect of Topical Latanoprost on Central Corneal Thickness.
Topics: Administration, Topical; Adolescent; Age of Onset; Antihypertensive Agents; Child; Child, Preschool; Cornea; Corneal Pachymetry; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Long-Term Care; Male; Organ Size; Sulfonamides; Thiophenes; Time Factors; Tonometry, Ocular | 2020 |
Hypokalemia associated with topical administration of dorzolamide 2% ophthalmic solution in cats.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cat Diseases; Cats; Double-Blind Method; Female; Hypokalemia; Male; Ophthalmic Solutions; Potassium; Proof of Concept Study; Prospective Studies; Retrospective Studies; Sulfonamides; Thiophenes | 2021 |
Corneal epithelium and limbal region alterations due to glaucoma medications evaluated by anterior segment optic coherence tomography: a case-control study.
Topics: Aged; Antihypertensive Agents; Benzalkonium Compounds; Brimonidine Tartrate; Case-Control Studies; Epithelium, Corneal; Female; Glaucoma; Humans; Latanoprost; Limbus Corneae; Male; Middle Aged; Ophthalmic Solutions; Preservatives, Pharmaceutical; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence | 2021 |
Comparing the effects and safety of dorzolamide hydrochloride + timolol maleate versus brimonidine after neodymium-doped yttrium aluminium garnet laser capsulotomy posterior capsule opacification.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lasers, Solid-State; Neodymium; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Yttrium | 2022 |
353 other study(ies) available for thiophenes and dorzolamide
Article | Year |
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Indirect chiral separation and analyses in human biological fluids of the stereoisomers of a thienothiopyran-2-sulfonamide (TRUSOPT), a novel carbonic anhydrase inhibitor with two chiral centers in the molecule.
Topics: Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Ophthalmic Solutions; Stereoisomerism; Sulfonamides; Thiophenes | 1992 |
MK-507 (L-671,152), a topically active carbonic anhydrase inhibitor, reduces aqueous humor production in monkeys.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Female; Fluorophotometry; Intraocular Pressure; Macaca fascicularis; Sulfonamides; Thiophenes; Tonometry, Ocular | 1991 |
Topically active carbonic anhydrase inhibitors for glaucoma.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sulfonamides; Thiophenes | 1991 |
A comparison of L-671,152 and MK-927, two topically effective ocular hypotensive carbonic anhydrase inhibitors, in experimental animals.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chymotrypsin; Ciliary Body; Erythrocytes; Female; In Vitro Techniques; Iris; Light Coagulation; Macaca fascicularis; Male; Ocular Hypertension; Ocular Hypotension; Rabbits; Sulfonamides; Thiophenes; Trabeculectomy | 1990 |
The ocular hypotensive effect of the topical carbonic anhydrase inhibitor L-671,152 in glaucomatous monkeys.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Female; Glaucoma; Intraocular Pressure; Laser Therapy; Macaca fascicularis; Molecular Structure; Sulfonamides; Thiophenes | 1990 |
Preclinical studies on L-671,152, a topically effective ocular hypotensive carbonic anhydrase inhibitor.
Topics: Animals; Carbonic Anhydrase Inhibitors; Intraocular Pressure; Macaca fascicularis; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1989 |
[The time required topical carbonic anhydrase inhibitor (MK-507) to take effect on intraocular pressure of normal human eyes].
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Depression, Chemical; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Time Factors | 1995 |
Effect of MK-507 on aqueous humor dynamics in normal human eyes.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Eye Proteins; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1994 |
Analytical chiral separation of the stereoisomers of a novel carbonic anhydrase inhibitor and its deethylated metabolite, and the assignment of absolute configuration of the human metabolite and chiral degradation products.
Topics: Biotransformation; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Humans; Molecular Conformation; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfonamides; Thiophenes | 1994 |
Determination of MK-507, a novel topically effective carbonic anhydrase inhibitor, and its de-ethylated metabolite in human whole blood, plasma, and urine by high-performance liquid chromatography.
Topics: Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Dealkylation; Humans; Indicators and Reagents; Ophthalmic Solutions; Reference Standards; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes | 1994 |
[Effect of topical carbonic anhydrase inhibitor (MK-507) on intraocular pressure of normal human eyes].
Topics: Acetazolamide; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Depression, Chemical; Eye Proteins; Humans; Intraocular Pressure; Sulfonamides; Thiophenes | 1994 |
Topical dorzolamide-induced hypotony and ciliochoroidal detachment in patients with previous filtration surgery.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Choroid Diseases; Ciliary Body; Female; Filtering Surgery; Glaucoma; Humans; Intraocular Pressure; Ocular Hypotension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Ultrasonography; Uveal Diseases | 1996 |
New therapeutic agents marketed in 1995.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acarbose; Alendronate; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carbonic Anhydrase Inhibitors; Drug Approval; Enzyme Inhibitors; Hypoglycemic Agents; Lansoprazole; Metformin; Omeprazole; Pregnadienes; Sulfonamides; Thiophenes; Trisaccharides; United States; United States Food and Drug Administration | 1996 |
[Successful pressure decrease and improved patient quality of life by Trusopt].
Topics: Adult; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1996 |
Nonlinear dorzolamide pharmacokinetics in rats: concentration-dependent erythrocyte distribution and drug-metabolite displacement interaction.
Topics: Administration, Oral; Analysis of Variance; Animals; Carbonic Anhydrase Inhibitors; Erythrocytes; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes | 1996 |
Membrane-bound carbonic anhydrase activity in the rat corneal endothelium and retina.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane; Cobalt; Endothelium, Corneal; Histocytochemistry; Male; Membrane Proteins; Rats; Rats, Wistar; Retina; Sulfonamides; Thiophenes | 1996 |
[Glaucoma. Current problems. Continuing education courses at the Ophthalmologic Clinic of the Eppendorf University Hospital, 9 December 1995].
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sulfonamides; Thiophenes | 1996 |
Ocular absorption, blood levels, and excretion of dorzolamide, a topically active carbonic anhydrase inhibitor.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes | 1997 |
Continuous intraocular pressure measurement by telemetry in alpha-chymotrypsin-induced glaucoma model in the rabbit: effects of timolol, dorzolamide, and epinephrine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chymotrypsin; Circadian Rhythm; Disease Models, Animal; Epinephrine; Female; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol | 1996 |
[Carbonic anhydrase inhibitors with topical action in the treatment of glaucomatous diseases. A preliminary note].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Combined Modality Therapy; Corneal Edema; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Time Factors | 1997 |
Low level determination of dorzolamide and its de-ethylated metabolite in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes | 1997 |
[Effectiveness of dorzolamide as added therapy in glaucoma patients with maximum tolerated drug therapy. A pilot study].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
An unusual side effect of Dorzolamide.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chemical Precipitation; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Sulfonamides; Thiophenes | 1997 |
[Ocular pulse amplitude and local carbonic anhydrase inhibition].
Topics: Adult; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes | 1997 |
Development and pharmacological characterization of a modified procedure for the measurement of carbonic anhydrase activity.
Topics: Acetazolamide; Animals; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cattle; Hydrogen-Ion Concentration; Isoenzymes; Kidney; Sulfonamides; Thiophenes | 1997 |
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol | 1998 |
2% dorzolamide and cornea: an ultrabiomicroscopic study.
Topics: Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Endothelium, Corneal; Glaucoma, Open-Angle; Humans; Image Processing, Computer-Assisted; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Ultrasonography; Visual Acuity | 1997 |
[Trusopt, a local carboanhydrase inhibitor, in the treatment of glaucoma in children (preliminary report)].
Topics: Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Female; Glaucoma; Humans; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1998 |
The effect of aqueous humor suppressants on intravitreal gas bubble duration in rabbits.
Topics: Absorption; Administration, Topical; Animals; Aqueous Humor; Clonidine; Fluorocarbons; Injections; Intraocular Pressure; Rabbits; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Time Factors; Timolol; Vitreous Body | 1998 |
[Glaucoma in the elderly].
Topics: Aged; Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Trabeculectomy | 1998 |
Glaucomatocyclitic crisis in a child.
Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Male; Pain; Prednisolone; Sulfonamides; Syndrome; Thiophenes; Timolol; Uveitis, Intermediate; Vision Disorders; Visual Acuity | 1998 |
Dorzolamide and timolol as suppressors of aqueous humor flow.
Topics: Adrenergic beta-Antagonists; Aqueous Humor; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sleep; Sulfonamides; Thiophenes; Timolol | 1998 |
Update in glaucoma: the new pharmacotherapies. Dorzolamide hydrochloride.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1998 |
[New drugs in glaucoma therapy].
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
[Treatment of glaucoma with carbonic anhydrase inhibitors in eyewash: medium term retrospective experience with dorzolamide].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Female; Glaucoma; Humans; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes | 1997 |
Combination of systemic acetazolamide and topical dorzolamide.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiophenes | 1998 |
Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV with N-hydroxysulfonamides--a novel class of intraocular pressure lowering agents.
Topics: Acetamides; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Glaucoma; Humans; Hydroxylamines; Intraocular Pressure; Isoenzymes; Male; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids; Thiophenes; Tosyl Compounds | 1998 |
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Contact allergy to dorzolamide eyedrops.
Topics: Antihypertensive Agents; Dermatitis, Allergic Contact; Female; Glaucoma; Humans; Middle Aged; Ophthalmic Solutions; Patch Tests; Skin; Sulfonamides; Thiophenes | 1998 |
[Modern anti-glaucoma drugs and their secondary effects].
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Dinoprost; Glaucoma; Humans; Quinoxalines; Sulfonamides; Thiophenes | 1998 |
Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Hydrogen-Ion Concentration; Injections, Intravenous; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Tonometry, Ocular | 1999 |
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Approval; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Netherlands; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1999 |
Regulation of intraocular pressure after water drinking.
Topics: Aqueous Humor; Blood-Aqueous Barrier; Carbonic Anhydrase Inhibitors; Drinking; Follow-Up Studies; Humans; Intraocular Pressure; Ophthalmic Solutions; Osmosis; Reference Values; Sulfonamides; Thiophenes | 1999 |
Irreversible corneal decompensation in patients treated with topical dorzolamide.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Corneal Edema; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Male; Middle Aged; Ophthalmic Solutions; Refractive Errors; Retrospective Studies; Sulfonamides; Thiophenes; Visual Acuity | 1999 |
Non-invasive assessment of ocular pharmacokinetics using Confocal Raman Spectroscopy.
Topics: Animals; Eye; Female; Rabbits; Spectrum Analysis, Raman; Sulfonamides; Thiophenes | 1999 |
Anorexia, depression and dementia induced by dorzolamide eyedrops (Trusopt).
Topics: Aged; Anorexia; Carbonic Anhydrase Inhibitors; Dementia; Depression; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Visual Acuity | 1999 |
[Is corneal thickness measurement reliable and useful?].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Cornea; Corneal Transplantation; Diabetes Mellitus; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Observer Variation; Ocular Hypertension; Reproducibility of Results; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Population pharmacokinetics of 2% topical dorzolamide in the aqueous humor of humans.
Topics: Absorption; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cataract Extraction; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1999 |
Clinical estimation of corneal endothelial pump function.
Topics: Administration, Topical; Adolescent; Adult; Body Water; Contact Lenses; Corneal Edema; Corneal Transplantation; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endothelium, Corneal; Humans; Permeability; Reference Values; Sulfonamides; Thiophenes | 1998 |
Dorzolamide-timolol combination versus concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Timolol | 1999 |
Carbonic anhydrase inhibitors. Part 71. Synthesis and ocular pharmacology of a new class of water-soluble, topically effective intraocular pressure lowering sulfonamides incorporating picolinoyl moieties.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbodiimides; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Humans; Intraocular Pressure; Male; Picolinic Acids; Rabbits; Solubility; Sulfonamides; Thiophenes; Water | 1999 |
Nephrolithiasis with dorzolamide.
Topics: Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Kidney; Kidney Calculi; Male; Sulfonamides; Thiophenes | 1999 |
The effectiveness and safety of dorzolamide 2% in addition to multiple topical antiglaucoma medications.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes | 1999 |
Neurobiological and psychophysical mechanisms underlying the oral sensation produced by carbonated water.
Topics: Action Potentials; Adult; Animals; Brain Stem; Carbonated Beverages; Carbonic Anhydrase Inhibitors; Electrophysiology; Female; Functional Laterality; Humans; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sensation; Sulfonamides; Thiophenes; Tongue; Trigeminal Nuclei | 1999 |
The effects of the carbonic anhydrase inhibitors methazolamide, diclofenamide and dorzolamide on trabecular meshwork and ciliary muscle contractility.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cattle; Ciliary Body; Dichlorphenamide; Methazolamide; Muscle Contraction; Sulfonamides; Thiophenes; Trabecular Meshwork | 1999 |
Optic nerve oxygen tension in pigs and the effect of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Animals; Blood Gas Analysis; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Injections, Intravenous; Ion-Selective Electrodes; Optic Disk; Optic Nerve; Oxygen; Oxygen Consumption; Polarography; Sulfonamides; Swine; Thiophenes | 1999 |
Sterile mucopurulent conjunctivitis associated with the use of dorzolamide eyedrops.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Conjunctiva; Conjunctivitis; Female; Glaucoma, Angle-Closure; Humans; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1999 |
Irreversible corneal decompensation in patients treated with topical dorzolamide.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Corneal Edema; Glaucoma; Humans; Sulfonamides; Thiophenes | 1999 |
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification. 1999; 43 (5): 344-6.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Humans; Intraocular Pressure; Phacoemulsification; Postoperative Complications; Sulfonamides; Thiophenes | 1999 |
Ultratrace analysis of drugs in biological fluids using affinity probe capillary electrophoresis: analysis of dorzolamide with fluorescently labeled carbonic anhydrase.
Topics: Animals; Body Fluids; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Electrophoresis, Capillary; Humans; Sensitivity and Specificity; Sulfonamides; Thiophenes | 2000 |
Delayed, recurrent hypotonous maculopathy following aqueous suppressant therapy in pseudophakia.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Macula Lutea; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prednisolone; Prodrugs; Pseudophakia; Recurrence; Retinal Diseases; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Increased optic nerve head blood flow after 1 week of twice daily topical brinzolamide treatment in Dutch-belted rabbits.
Topics: Animals; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Hemodynamics; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Ophthalmic Solutions; Optic Disk; Rabbits; Sulfonamides; Thiazines; Thiophenes | 2000 |
PHARMAC complicates treatment of glaucoma.
Topics: Antihypertensive Agents; Glaucoma; Government Agencies; Humans; Latanoprost; New Zealand; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 1999 |
Interactions between carbonic anhydrase and its inhibitors revealed by gel electrophoresis and circular dichroism.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Methazolamide; Sodium Dodecyl Sulfate; Sulfonamides; Thiophenes; Titrimetry; Urea | 2000 |
Comparison of the efficacy and safety of latanoprost 0.005% compared to brimonidine 0.2% or dorzolamide 2% when added to a topical beta-adrenergic blocker in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Tonometry, Ocular | 2000 |
Bullous pemphigoid possibly triggered and exacerbated by ophthalmic preparations.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diabetes Mellitus, Type 2; Glaucoma; Humans; Levobunolol; Male; Middle Aged; Mouth Mucosa; Ophthalmic Solutions; Pemphigoid, Bullous; Sulfonamides; Thiophenes; Timolol | 2000 |
Optic nerve oxygen tension: effects of intraocular pressure and dorzolamide.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Infusions, Intravenous; Intraocular Pressure; Optic Nerve; Oxygen; Sulfonamides; Swine; Thiophenes | 2000 |
Marginal keratitis: an uncommon form of topical dorzolamide allergy.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Keratitis; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2000 |
[Central corneal thickness in normal eyes, patients with ocular hypertension, normal-pressure and open-angle glaucomas--a clinical study].
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cornea; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Reference Values; Sex Distribution; Sulfonamides; Thiophenes | 2000 |
Comparison of the ocular hypotensive effect of brimonidine, dorzolamide, latanoprost, or artificial tears added to timolol in glaucomatous monkey eyes.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Intraocular Pressure; Latanoprost; Macaca fascicularis; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Random Allocation; Sulfonamides; Thiophenes; Timolol | 2000 |
[Dorzolamide: hypotensive efficacy in combination with beta-blockers. Long-term results].
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma; Humans; Male; Retrospective Studies; Sulfonamides; Thiophenes; Time Factors | 2000 |
[Effect of Trusopt on normal intraocular pressure values in children].
Topics: Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Humans; Intraocular Pressure; Sulfonamides; Thiophenes | 2000 |
Effect of topical administration of 2% dorzlamide hydrochloride or 2% dorzlamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chemistry, Pharmaceutical; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Random Allocation; Regression Analysis; Sulfonamides; Thiophenes; Timolol | 2001 |
Carbonic anhydrase inhibitors: synthesis and inhibition against isozymes I, II and IV of topically acting antiglaucoma sulfonamides incorporating cis-5-norbornene-endo-3-carboxy-2-carboxamido moieties.
Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Escherichia coli; Glaucoma; Humans; Indicators and Reagents; Isoenzymes; Kinetics; Norbornanes; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes | 2001 |
[Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District].
Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Disease Progression; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Office Visits; Pilocarpine; Poland; Sulfonamides; Thiophenes; Timolol | 2000 |
Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs.
Topics: Administration, Oral; Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Administration Schedule; Female; Glaucoma; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Sulfonamides; Thiophenes; Treatment Outcome | 2001 |
Effects of topical application of a 2% solution of dorzolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Dogs; Female; Fluorophotometry; Glaucoma; Intraocular Pressure; Male; Random Allocation; Sulfonamides; Thiophenes | 2001 |
Allergic contact dermatitis due to dorzolamide eyedrops.
Topics: Antihypertensive Agents; Conjunctivitis, Allergic; Dermatitis, Allergic Contact; Diagnosis, Differential; Glaucoma; Humans; Male; Middle Aged; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes | 2001 |
[Severe hyperglycemia caused by dorzolamide].
Topics: Antihypertensive Agents; Female; Humans; Hyperglycemia; Middle Aged; Severity of Illness Index; Sulfonamides; Thiophenes | 2001 |
[Additive effects of topical carbonic anhydrase inhibitors].
Topics: Aged; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Drug points. Exacerbation of angina associated with latanoprost.
Topics: Acute Disease; Aged; Angina Pectoris; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Vasoconstrictor Agents | 2001 |
Allergic contact blepharoconjunctivitis from dorzolamide.
Topics: Aged; Blepharitis; Carbonic Anhydrase Inhibitors; Conjunctivitis, Allergic; Dermatitis, Allergic Contact; Glaucoma; Humans; Male; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes | 2001 |
[Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Rabbits; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol | 2001 |
[The pH reaction in aqueous humor to antiglaucoma agents of various concentrations and pH levels].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aqueous Humor; Female; Glaucoma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Male; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Refractive change after dorzolamide use in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Refractive Errors; Sulfonamides; Thiophenes | 2001 |
Application of TLC-densitometry, first-derivative UV-spectrophotometry and ratio derivative spectrophotometry for the determination of dorzolamide hydrochloride and timolol maleate.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chromatography, Thin Layer; Densitometry; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes; Timolol | 2002 |
Periorbital dermatitis as a side effect of topical dorzolamide.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Eruptions; Facial Dermatoses; Female; Glaucoma; Humans; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes | 2002 |
Simultaneous determination of dorzolamide HCL and timolol maleate in eye drops by two different spectroscopic methods.
Topics: Adrenergic beta-Antagonists; Algorithms; Antihypertensive Agents; Calibration; Drug Combinations; Ophthalmic Solutions; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes; Timolol | 2002 |
Rapid high-performance liquid chromatographic assay of dorzolamide in rabbit aqueous humor.
Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Male; Rabbits; Sulfonamides; Thiophenes | 2002 |
[Corneal descompensation in patients with endothelial compromise treated with topical dorzolamide].
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cornea; Endothelium, Corneal; Filtering Surgery; Glaucoma; Humans; Keratoplasty, Penetrating; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes; Vitrectomy | 2002 |
The effects of new topical treatments on management of glaucoma in Scotland: an examination of ophthalmological health care.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Costs; Drug Prescriptions; Glaucoma; Humans; Latanoprost; Middle Aged; Miotics; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Quinoxalines; Retrospective Studies; Scotland; Sulfonamides; Sympathomimetics; Thiophenes; Trabeculectomy | 2002 |
Cutaneous drug reaction case reports: from the world literature.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Capecitabine; Carbamates; Ceftriaxone; Clonidine; Deoxycytidine; Diagnosis, Differential; Drug Eruptions; Ethacridine; Female; Fluorouracil; Humans; Immunosuppressive Agents; Indapamide; Isotretinoin; Isoxazoles; Leflunomide; Male; Middle Aged; Nelfinavir; Phenylcarbamates; Rivastigmine; Salicylates; Severity of Illness Index; Sulfonamides; Thiophenes | 2002 |
Effect of Xalatan(R) and Cosopt(R) on the vascular tone of quiescent isolated pig ciliary arteries.
Topics: Animals; Antihypertensive Agents; Ciliary Arteries; Culture Techniques; Dose-Response Relationship, Drug; Drug Combinations; Intraocular Pressure; Latanoprost; Potassium Chloride; Prostaglandins F, Synthetic; Sulfonamides; Swine; Thiophenes; Timolol; Vasoconstriction | 2002 |
Additive intraocular pressure lowering effect of various medications with latanoprost.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Synergism; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes | 2002 |
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.
Topics: Administration, Topical; Amiloride; Animals; Antihypertensive Agents; Aqueous Humor; Bumetanide; Diuretics; Electrophysiology; Female; Intraocular Pressure; Male; Mice; Sodium-Hydrogen Exchangers; Sulfonamides; Thiophenes | 2002 |
[Weill-Marchesani syndrome. Late athalamia following antiglaucomatous surgery].
Topics: Abnormalities, Multiple; Adult; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Dwarfism; Female; Fingers; Glaucoma, Angle-Closure; Hand Deformities, Congenital; Humans; Intraocular Pressure; Iridectomy; Lens Implantation, Intraocular; Lens, Crystalline; Mitomycins; Phacoemulsification; Postoperative Complications; Sulfonamides; Syndrome; Thiophenes; Trabeculectomy; Vitrectomy | 2002 |
Inhibition of carbonic anhydrase activity in cultured bovine corneal endothelial cells by dorzolamide.
Topics: Animals; Bicarbonates; Carbonates; Carbonic Anhydrase Inhibitors; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Corneal; Female; Hydrogen-Ion Concentration; Isotonic Solutions; Osmolar Concentration; Ringer's Solution; Sulfonamides; Thiophenes | 2002 |
The pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary study.
Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol | 2002 |
Choroidal detachment induced by dorzolamide 20 years after cataract surgery.
Topics: Aged; Antihypertensive Agents; Cataract Extraction; Choroid Diseases; Drug Therapy, Combination; Female; Humans; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Primary glaucoma in Burmese cats.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Breeding; Cat Diseases; Cats; Female; Glaucoma; Latanoprost; Ophthalmic Solutions; Prednisolone; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2002 |
Functional analysis of retinal vessel diameter reaction to artificially raised intraocular pressure in glaucoma patients with and without dorzolamide therapy.
Topics: Adult; Aged; Antihypertensive Agents; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Retinal Vessels; Sulfonamides; Thiophenes; Vascular Resistance | 2002 |
Blockers of carbonic anhydrase can cause increase of retinal capillary diameter, decrease of extracellular and increase of intracellular pH in rat retinal organ culture.
Topics: Acetazolamide; Actins; Animals; Capillaries; Carbonic Anhydrase Inhibitors; Extracellular Space; Female; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Male; Muscle, Smooth, Vascular; Organ Culture Techniques; Pericytes; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Vasodilation | 2003 |
[Glaucoma: an ocular blood flow disorder?].
Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Rheology; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Timolol | 2003 |
Experience with COSOPT, the fixed combination of timolol and dorzolamide, gained in Swiss ophthalmologists' offices.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Physicians' Offices; Practice Patterns, Physicians'; Prostaglandins F, Synthetic; Sulfonamides; Switzerland; Thiophenes; Timolol; Treatment Outcome | 2003 |
Effects of twice daily application of 2% dorzolamide on intraocular pressure in normal cats.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cats; Female; Intraocular Pressure; Male; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiophenes; Tonometry, Ocular | 2003 |
Comparison of the efficacy of the fixed-combination timolol/dorzolamide versus concomitant administration of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Aged; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells.
Topics: Animals; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Calcium; Carteolol; Cell Death; Dose-Response Relationship, Drug; Epinephrine; Glaucoma; Glutamic Acid; Latanoprost; Mice; Neuroblastoma; Neurons; Neuroprotective Agents; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol; Tumor Cells, Cultured | 2003 |
The free amino acids and the aqueous humor pH after antiglaucomatics in vitro.
Topics: Aged; Aged, 80 and over; Amino Acids; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Male; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2003 |
Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzolamide, in Swiss ophthalmologists' offices.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cluster Analysis; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Ophthalmology; Sulfonamides; Switzerland; Thiophenes; Timolol | 2003 |
Topical dorzolamide and metabolic acidosis in a neonate.
Topics: Acidosis; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Humans; Infant, Newborn; Male; Sulfonamides; Thiophenes | 2003 |
Rapid and sensitive HPLC method for the simultaneous determination of dorzolamide hydrochloride and timolol maleate in eye drops with diode-array and UV detection.
Topics: Adrenergic beta-Antagonists; Calibration; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Indicators and Reagents; Ophthalmic Solutions; Reproducibility of Results; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes; Timolol | 2003 |
Patient persistency with pharmacotherapy in the management of glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cohort Studies; Drug Utilization; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Patient Compliance; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes | 2003 |
Switching from systemic to the topical carbonic anhydrase inhibitor dorzolamide: effect on the quality of life of glaucoma patients with drug-related side effects.
Topics: Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Glaucoma, Open-Angle; Health Status Indicators; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quality of Life; Sulfonamides; Thiophenes | 2003 |
[Effects of ocular hypotensive agents on the circadian rhythm in intraocular pressure in rabbits as measured by telemetry].
Topics: Animals; Circadian Rhythm; Intraocular Pressure; Male; Quinazolines; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol | 2003 |
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.
Topics: Administration, Topical; Animals; Benzolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Esters; Glaucoma; Humans; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes | 2003 |
Prescription of topical antiglaucoma agents for patients with contraindications to beta-blockers.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Contraindications; Databases, Factual; Drug Prescriptions; Female; Glaucoma; Humans; Latanoprost; Male; Middle Aged; National Health Programs; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quebec; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2003 |
Ocular factors relevant to anti-glaucomatous eyedrop-related keratoepitheliopathy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carteolol; Dinoprost; Drug Therapy, Combination; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Keratitis; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Risk Factors; Sulfonamides; Tears; Thiophenes; Timolol | 2003 |
Voltammetric and HPLC determination of dorzolamide hydrochloride in eye drops.
Topics: Buffers; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Indicators and Reagents; Ophthalmic Solutions; Potentiometry; Reproducibility of Results; Sulfonamides; Thiophenes | 2003 |
Dorzolamide induces vasodilatation in isolated pre-contracted bovine retinal arteries.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cattle; Culture Techniques; Dose-Response Relationship, Drug; Retina; Retinal Artery; Sulfonamides; Thiophenes; Vasoconstriction; Vasodilation; Vasodilator Agents | 2004 |
Optic nerve oxygen tension: the effects of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Drug Interactions; Heart Rate; Intraocular Pressure; Optic Disk; Oxygen; Partial Pressure; Sulfonamides; Swine; Thiophenes; Timolol | 2004 |
Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Pulsatile Flow; Regional Blood Flow; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
Effects of dorzolamide hydrochloride on ocular tissues.
Topics: Animals; Blotting, Western; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chromatography, High Pressure Liquid; Eye; Female; Immunohistochemistry; Instillation, Drug; Ophthalmic Solutions; Rabbits; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Tissue Distribution | 2004 |
[Effect of various anti-glaucoma eyedrops on human corneal epithelial cells].
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cell Division; Dinoprost; Epithelium, Corneal; Glaucoma; Growth Inhibitors; Humans; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2004 |
Lichenoid drug eruption secondary to topical timolol and dorzolamide eye-drops.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Drug Eruptions; Glaucoma; Humans; Leg Dermatoses; Lichenoid Eruptions; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
Studies on the mechanism of action of timolol and on the effects of suppression and redirection of aqueous flow on outflow facility.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aqueous Humor; Ascorbic Acid; Carbonic Anhydrase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibronectins; Macaca fascicularis; Macaca mulatta; Sulfonamides; Thiophenes; Timolol | 2004 |
Trends in glaucoma surgery before and after the introduction of new topical glaucoma pharmacotherapies.
Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy; Drug Utilization; Filtering Surgery; Glaucoma, Open-Angle; Humans; Inpatients; Latanoprost; Medicare; Ophthalmic Solutions; Outpatients; Prevalence; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; United States | 2004 |
[Intraocular pressure in rabbits after administration of 10% L-arginine HCl in 2% Trusopt].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Pupil; Rabbits; Sulfonamides; Thiophenes | 2004 |
Accelerated idioventricular rhythm associated to ophthalmic timolol/dorzolamide solution.
Topics: Accelerated Idioventricular Rhythm; Antihypertensive Agents; Drug Combinations; Electrocardiography; Female; Glaucoma, Open-Angle; Humans; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
Endothelial changes associated with topical dorzolamide do appear to be significant.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Corneal Diseases; Endothelium, Corneal; Humans; Sulfonamides; Thiophenes | 2004 |
Alphagan allergy may increase the propensity for multiple eye-drop allergy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cross Reactions; Drug Administration Schedule; Drug Hypersensitivity; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Longitudinal Studies; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2005 |
An unusual appearance of limbal conjunctival follicles in a patient on brimonidine and dorzolamide.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Conjunctival Diseases; Glaucoma, Open-Angle; Humans; Male; Quinoxalines; Sulfonamides; Thiophenes | 2005 |
Dorzolamide-induced choroidal detachment in a surgically untreated eye.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Choroid Diseases; Female; Glaucoma, Open-Angle; Humans; Sulfonamides; Thiophenes; Ultrasonography | 2004 |
[Comparison of the effectiveness of a mixture of 10% L-arginine and HCl combined with 0.5% Timoptol and with 2% Trusopt: and the individual components on intraocular pressure in an experiment on rabbits].
Topics: Animals; Antihypertensive Agents; Arginine; Carbonic Anhydrase Inhibitors; Drug Combinations; Intraocular Pressure; Male; Rabbits; Sulfonamides; Thiophenes; Timolol | 2004 |
[Neuroprotection and vasoprotection in glaucoma].
Topics: Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Carteolol; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Neuroprotective Agents; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2004 |
The effect of carbonic anhydrase inhibition on leptin secretion by rat adipose tissue.
Topics: Adipose Tissue; Animals; Carbonic Anhydrase III; Dexamethasone; Enzyme Inhibitors; Epididymis; Insulin; Leptin; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes | 2004 |
Influence of inorganic mobile phase additives on the retention, efficiency and peak symmetry of protonated basic compounds in reversed-phase liquid chromatography.
Topics: Algorithms; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Indicators and Reagents; Inorganic Chemicals; Labetalol; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2004 |
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration.
Topics: Administration, Topical; Animals; Chemistry, Pharmaceutical; Cyclodextrins; Eye; Rabbits; Sulfonamides; Thiophenes | 2005 |
Contact dermatitis caused by allergy to dorzolamide.
Topics: Aged; Dermatitis, Allergic Contact; Diagnosis, Differential; Glaucoma, Open-Angle; Humans; Male; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes | 2005 |
Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Injections, Intravenous; Ion-Selective Electrodes; Optic Nerve; Oxygen; Partial Pressure; Polarography; Retina; Retinal Vessels; Sulfonamides; Swine; Thiophenes; Vasodilation | 2005 |
Topically administered timolol and dorzolamide reduce intraocular pressure and protect retinal ganglion cells in a rat experimental glaucoma model.
Topics: Animals; Antihypertensive Agents; Cell Count; Cell Survival; Cytoprotection; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Timolol | 2005 |
Volumetric colour Doppler imaging: a useful tool for the determination of ocular blood flow in glaucoma patients?
Topics: Adult; Antihypertensive Agents; Blood Flow Velocity; Glaucoma; Humans; Middle Aged; Observer Variation; Ophthalmic Artery; Regional Blood Flow; Reproducibility of Results; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2006 |
European Glaucoma Prevention Study.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes | 2005 |
Toxic epidermal necrolysis secondary to timolol, dorzolamide, and latanoprost eyedrops.
Topics: Antihypertensive Agents; Female; Glaucoma; Humans; Latanoprost; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Stevens-Johnson Syndrome; Sulfonamides; Thiophenes; Timolol | 2005 |
The in vitro effects of some pesticides on carbonic anhydrase activity of Oncorhynchus mykiss and Cyprinus carpio carpio fish.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Carps; Diazinon; In Vitro Techniques; Insecticides; Nitriles; Oncorhynchus mykiss; Pyrethrins; Sulfonamides; Thiazines; Thiophenes; Water Pollutants, Chemical | 2006 |
Dorzolamide and timolol saves retinal ganglion cells in glaucomatous adult rats.
Topics: Animals; Antihypertensive Agents; Cell Count; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Pilot Projects; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Time Factors; Timolol | 2005 |
Effect of topical dorzolamide on rabbit central corneal thickness.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cornea; Male; Rabbits; Random Allocation; Sulfonamides; Thiophenes; Ultrasonography | 2006 |
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase.
Topics: Animals; Annexin A5; Apoptosis; Carbonic Anhydrase Inhibitors; Caspase 3; Caspases; Cell Culture Techniques; Cell Survival; Flow Cytometry; Glyoxal; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Situ Nick-End Labeling; Lysine; Neurons; Neuroprotective Agents; Pyruvaldehyde; Rats; Reactive Oxygen Species; Retina; Sulfonamides; Thiophenes | 2006 |
Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells.
Topics: Animals; Antihypertensive Agents; Betaxolol; Calcium; Endothelium, Corneal; Glaucoma; Levobunolol; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Timolol | 2006 |
Allergic contact dermatitis from timolol and dorzolamide eye drops.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dermatitis, Allergic Contact; Epinephrine; Female; Glaucoma; Humans; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes; Timolol | 2006 |
Effects of topical antiglaucoma application on conjunctival impression cytology specimens.
Topics: Administration, Topical; Antihypertensive Agents; Conjunctiva; Cross-Sectional Studies; Drug Therapy, Combination; Epithelium; Glaucoma, Open-Angle; Humans; Latanoprost; Metaplasia; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2006 |
[Intraocular pressure after ND: YAG laser capsulotomy in pseudophakic patients with glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cataract Extraction; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Preoperative Care; Pseudophakia; Quinoxalines; Sulfonamides; Thiophenes | 2006 |
Optic nerve pH and PO2: the effects of carbonic anhydrase inhibition, and metabolic and respiratory acidosis.
Topics: Acidosis, Respiratory; Ammonium Chloride; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Optic Disk; Optic Nerve; Oxygen; Oxygen Consumption; Partial Pressure; Polarography; Sulfonamides; Swine; Thiophenes | 2006 |
Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs.
Topics: Administration, Topical; Aged; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Carteolol; Case-Control Studies; Chemokines; Cloprostenol; Cytokines; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Tears; Thiophenes; Timolol | 2007 |
Use of dorzolamide for patients with X-linked retinoschisis.
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Cysts; Fovea Centralis; Humans; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2006 |
Effect of 2% dorzolamide on retinal blood flow: a study on juvenile primary open-angle glaucoma patients already receiving 0.5% timolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2007 |
Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Humans; Macular Edema; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2006 |
Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
[Blurred vision after instillation of topical carbonic anhydrase inhibitor].
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Male; Middle Aged; Sulfonamides; Tears; Thiazines; Thiophenes; Time Factors; Visual Acuity | 2006 |
The additive effect of topical dorzolamide and systemic acetazolamide in pediatric glaucoma.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 2006 |
Drug-induced ectropion: what is best practice?
Topics: Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Ectropion; Eyelids; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes | 2007 |
Dorzolamide hydrochloride: an antiglaucoma agent.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Crystallization; Crystallography, X-Ray; Glaucoma; Humans; Molecular Conformation; Sulfonamides; Thiophenes | 2007 |
Anosmia as an adverse effect of dorzolamid.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Olfaction Disorders; Sulfonamides; Thiophenes | 2007 |
[Case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy].
Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Argon; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Ophthalmic Solutions; Quinazolines; Sulfonamides; Thiophenes; Trabeculectomy; Treatment Outcome | 2007 |
Acute visual loss due to serous retinal detachment from acquired optic pit may be a rare presentation of primary open-angle glaucoma.
Topics: Acute Disease; Antihypertensive Agents; Diclofenac; Drug Therapy, Combination; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Middle Aged; Optic Disk; Optic Nerve Diseases; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Vision Disorders; Visual Acuity | 2007 |
Hypotony and choroidal detachment as a complication of topical combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract Extraction; Choroid Diseases; Chronic Disease; Drug Interactions; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Trabeculectomy | 2007 |
[Toxic epidermal necrolysis following eyedrop treatment for glaucoma].
Topics: Conjunctivitis; Female; Genital Diseases, Female; Glaucoma; Humans; Middle Aged; Ophthalmic Solutions; Stevens-Johnson Syndrome; Sulfonamides; Thiophenes | 2007 |
Hypotensive effect of profilin on rabbit intraocular pressure.
Topics: Animals; Antihypertensive Agents; Intraocular Pressure; Latanoprost; Pilocarpine; Profilins; Prostaglandins F, Synthetic; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; Sulfonamides; Thiophenes | 2007 |
Diuretics, placebos, and the European glaucoma prevention study.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Diuretics; Europe; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Prevalence; Randomized Controlled Trials as Topic; Retinal Hemorrhage; Risk Factors; Sulfonamides; Thiophenes | 2007 |
Variable involvement of the perivascular retinal tissue in carbonic anhydrase inhibitor induced relaxation of porcine retinal arterioles in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetazolamide; Animals; Arterioles; Carbonic Anhydrase Inhibitors; Muscle, Smooth, Vascular; Myography; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasoconstrictor Agents; Vasodilation | 2007 |
Costs and effectiveness of travoprost versus a dorzolamide + timolol fixed combination in first-line treatment of glaucoma: analysis conducted on the United Kingdom General Practitioner Research Database.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cost-Benefit Analysis; Databases, Factual; Drug Combinations; Drug Costs; Female; Glaucoma; Humans; Male; Physicians, Family; Sulfonamides; Thiophenes; Timolol; Travoprost; United Kingdom | 2007 |
Carbonic anhydrases IV and IX: subcellular localization and functional role in mouse skeletal muscle.
Topics: Animals; Carbonic Anhydrase IV; Carbonic Anhydrase IX; Carbonic Anhydrases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Mice; Mice, Knockout; Microscopy, Confocal; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Sarcolemma; Sarcoplasmic Reticulum; Sulfonamides; Thiophenes; Time Factors; Transport Vesicles | 2008 |
[Acute closed-angle glaucoma after gynecological surgery under general anesthesia].
Topics: Acetazolamide; Acute Disease; Anesthesia, General; Atropine; Combined Modality Therapy; Corneal Edema; Dexamethasone; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Humans; Laser Therapy; Mannitol; Middle Aged; Mydriasis; Pilocarpine; Postoperative Complications; Sulfonamides; Thiophenes; Timolol; Vomiting | 2007 |
Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Prevalence; Risk Factors; Sulfonamides; Thiophenes; Treatment Outcome | 2008 |
Adoption of new antiglaucoma drugs in Finland: impact of changes in copayment.
Topics: Carbonic Anhydrase Inhibitors; Data Collection; Data Interpretation, Statistical; Drug Utilization; Finland; Glaucoma; Humans; Insurance, Health, Reimbursement; Latanoprost; Models, Statistical; Prostaglandins; Prostaglandins F, Synthetic; Regression Analysis; Sulfonamides; Thiophenes | 2007 |
Drug modification of angiogenesis in a rat cornea model.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Corneal Neovascularization; Corneal Stroma; Disease Models, Animal; Drug Implants; Fibroblast Growth Factor 2; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Timolol | 2008 |
Systemic contact dermatitis to dorzolamide eye drops.
Topics: Aged; Aged, 80 and over; Allergens; Dermatitis, Allergic Contact; Dermatitis, Perioral; Diagnosis, Differential; Female; Humans; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes | 2008 |
Chronic kidney disease--a disease domain complex.
Topics: Aged; Alendronate; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Bone Density Conservation Agents; Calcium; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy; Female; Glomerular Filtration Rate; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; Kidney Failure, Chronic; Metoprolol; Nitroglycerin; Sulfonamides; Thiophenes | 2008 |
Dorzolamide increases retinal oxygen tension after branch retinal vein occlusion.
Topics: Animals; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Fluorescein Angiography; Hypoxia; Injections, Intravenous; Ion-Selective Electrodes; Ischemia; Oxygen; Oxygen Consumption; Partial Pressure; Retina; Retinal Vein Occlusion; Sulfonamides; Swine; Thiophenes | 2008 |
Erythema multiforme after use of topical dorzolamide.
Topics: Administration, Topical; Aged, 80 and over; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Cataract Extraction; Drug Eruptions; Erythema Multiforme; Female; Glaucoma; Humans; Hydrocortisone; Sulfonamides; Thiophenes; Visual Acuity | 2008 |
[Comparative study of the effects of two anti-glaucomatous drugs on the corneal thickness in rabbits with corneal autografts].
Topics: Animals; Antihypertensive Agents; Cornea; Corneal Transplantation; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes | 2008 |
Estimation of ocular rigidity based on measurement of pulse amplitude using pneumotonometry and fundus pulse using laser interferometry in glaucoma.
Topics: Aged; Blood Pressure; Drug Therapy, Combination; Female; Fundus Oculi; Glaucoma, Open-Angle; Humans; Interferometry; Intraocular Pressure; Lasers; Latanoprost; Light; Male; Middle Aged; Prostaglandins F, Synthetic; Pulse; Reference Values; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
Additive effect of dorzolamide hydrochloride to patients taking travoprost: a retrospective study.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Retrospective Studies; Sulfonamides; Thiophenes; Travoprost; Treatment Outcome; Visual Fields | 2008 |
[Toxic epidermal necrolysis following dorzolamide eyedrops].
Topics: Aged; Critical Care; Drug Therapy, Combination; Eye Diseases; Female; Glaucoma, Open-Angle; Humans; Metronidazole; Ophthalmic Solutions; Pheniramine; Prednisolone; Stevens-Johnson Syndrome; Sulfonamides; Thiophenes | 2008 |
The vasodilating effect of acetazolamide and dorzolamide involves mechanisms other than carbonic anhydrase inhibition.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetazolamide; Acidosis; Animals; Arterioles; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hypercapnia; Muscle, Smooth, Vascular; Myography; Nifedipine; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
[Intraocular pressure after instillation of amino acid arginine and combination of two antiglaucomatics (Trusopt + Xalatane mixture) in rabbits].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes | 2008 |
Relation of response to treatment with dorzolamide in X-linked retinoschisis to the mechanism of functional loss in retinoschisin.
Topics: Adult; Blotting, Western; Carbonic Anhydrase Inhibitors; Cysts; DNA Mutational Analysis; Eye Proteins; Gene Expression Regulation; Humans; Male; Mutagenesis, Site-Directed; Mutation, Missense; Ophthalmic Solutions; Polymerase Chain Reaction; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Young Adult | 2009 |
Intraocular pressure lowering, change of antiapoptotic molecule expression, and neuroretinal changes by dorzolamide 2%/timolol 0.5% combination in a chronic ocular hypertension rat model.
Topics: Animals; bcl-X Protein; Cell Survival; Disease Models, Animal; Drug Combinations; Glial Fibrillary Acidic Protein; Intraocular Pressure; Male; Ocular Hypertension; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; RNA, Messenger; Sulfonamides; Thiophenes; Timolol | 2008 |
Short-term effect of topical dorzolamide hydrochloride on intrastromal corneal pressure in rabbit corneas in vivo.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Corneal Stroma; Drug Administration Schedule; Male; Pressure; Rabbits; Sulfonamides; Thiophenes; Time Factors | 2009 |
Effects of dorzolamide on choroidal blood flow, ciliary blood flow, and aqueous production in rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Choroid; Ciliary Body; Female; Fluorophotometry; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Rabbits; Regional Blood Flow; Sulfonamides; Thiophenes; Vasodilation | 2009 |
Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2009 |
Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits.
Topics: Acrylates; Adhesives; Animals; Antihypertensive Agents; Biological Transport; Cornea; Dose-Response Relationship, Drug; Drug Compounding; Gels; In Vitro Techniques; Intraocular Pressure; Male; Mucous Membrane; Ophthalmic Solutions; Permeability; Rabbits; Sulfonamides; Terpenes; Thiophenes | 2010 |
Nanoemulsion as a potential ophthalmic delivery system for dorzolamide hydrochloride.
Topics: Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cornea; Drug Delivery Systems; Drug Stability; Emulsions; Eye Diseases; Glaucoma; Hydrogen-Ion Concentration; Irritants; Male; Nanoparticles; Ophthalmic Solutions; Osmolar Concentration; Particle Size; Rabbits; Rheology; Solubility; Sulfonamides; Surface Tension; Thiophenes; Viscosity | 2009 |
Corneal thickness and glaucoma medications.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cornea; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Relative efficacy of prostaglandins.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Choroidal detachment in association with topical dorzolamide: is hypotony always the cause?
Topics: Aged; Antihypertensive Agents; Choroid Diseases; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Visual Acuity | 2009 |
Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation.
Topics: Acetazolamide; Animals; Aorta, Thoracic; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Sodium Nitrite; Sulfonamides; Thiophenes; Vasodilation | 2009 |
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma.
Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Drug Discovery; Glaucoma, Open-Angle; Models, Molecular; Molecular Structure; Nitric Oxide; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2009 |
Retinal arteriolar vascular reactivity in untreated and progressive primary open-angle glaucoma.
Topics: Administration, Topical; Aged; Arterioles; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Disease Progression; Glaucoma, Open-Angle; Humans; Hypercapnia; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Optic Disk; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes | 2010 |
The effects of combination glaucoma medications on ocular surface epithelial cells.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Conjunctiva; Cornea; Drug Combinations; Epithelial Cells; Humans; In Vitro Techniques; Ophthalmic Solutions; Quinoxalines; Sodium Chloride; Sulfonamides; Thiophenes; Timolol | 2009 |
Hyaluronic acid modified chitosan nanoparticles for effective management of glaucoma: development, characterization, and evaluation.
Topics: Adrenergic beta-Antagonists; Animals; Biological Availability; Carbonic Anhydrase Inhibitors; Chitosan; Drug Carriers; Glaucoma; Hyaluronic Acid; Nanoparticles; Rabbits; Sulfonamides; Thiophenes; Timolol | 2010 |
Efficacy of sustained topical dorzolamide therapy for cystic macular lesions in patients with X-linked retinoschisis.
Topics: Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Eye Proteins; Follow-Up Studies; Humans; Intraocular Pressure; Macular Edema; Middle Aged; Ophthalmic Solutions; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Young Adult | 2010 |
Simultaneous quantification of carteolol and dorzolamide in rabbit aqueous humor and ciliary body by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carteolol; Chromatography, High Pressure Liquid; Ciliary Body; Disease Models, Animal; Humans; Male; Ocular Hypertension; Rabbits; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Thiophenes | 2010 |
Use of rituximab for periocular and intraocular mucosa-associated lymphoid tissue lymphoma.
Topics: Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Brimonidine Tartrate; Drug Therapy, Combination; Eye Neoplasms; Female; Glaucoma; Humans; Latanoprost; Loteprednol Etabonate; Lymphoma, B-Cell, Marginal Zone; Middle Aged; Parotid Neoplasms; Prostaglandins F, Synthetic; Quinoxalines; Rituximab; Sulfonamides; Thiophenes; Timolol | 2010 |
Diagnostic and therapeutic challenges.
Topics: Acetazolamide; Adult; Electroretinography; Fluorescein Angiography; Fundus Oculi; Humans; Macular Edema; Male; Ophthalmic Solutions; Sulfonamides; Tablets; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Visual Acuity; Visual Fields | 2011 |
Development of dorzolamide hydrochloride in situ gel nanoemulsion for ocular delivery.
Topics: Animals; Antihypertensive Agents; Biological Availability; Delayed-Action Preparations; Emulsions; Excipients; Eye; Gels; Male; Nanoparticles; Poloxamer; Rabbits; Sulfonamides; Surface-Active Agents; Thiophenes; Time Factors | 2010 |
Chiral separation and quantitation of dorzolamide hydrochloride enantiomers by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Molecular Conformation; Stereoisomerism; Sulfonamides; Temperature; Thiophenes | 2010 |
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugs: formulation of dorzolamide eye drop microparticle suspension.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Delayed-Action Preparations; Drug Stability; Excipients; gamma-Cyclodextrins; Hydrogen-Ion Concentration; Hypromellose Derivatives; Methazolamide; Methylcellulose; Polymers; Rabbits; Solubility; Sulfonamides; Suspensions; Thiazines; Thiophenes; Time Factors; Tissue Distribution | 2010 |
Predictors for visual field progression.
Topics: Antihypertensive Agents; Blood Flow Velocity; Disease Progression; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Optic Disk; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision Disorders; Visual Fields | 2010 |
Efficacy of sustained topical dorzolamide therapy for cystic macular lesions in patients with retinitis pigmentosa and usher syndrome.
Topics: Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Follow-Up Studies; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Retina; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Usher Syndromes; Visual Acuity; Young Adult | 2010 |
Efficacy of topical dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Humans; Macular Edema; Male; Retinal Cone Photoreceptor Cells; Retinal Diseases; Sulfonamides; Syndrome; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Visual Field Tests; Young Adult | 2010 |
Skin eruption and thrombocytopaenia in a woman with glaucoma: a case report.
Topics: Anti-Infective Agents; Antihypertensive Agents; Biopsy; Dapsone; Drug Eruptions; Female; Glaucoma; Humans; Liver Function Tests; Middle Aged; Ophthalmic Solutions; Platelet Count; Sulfonamides; Thiophenes; Thrombocytopenia; Timolol | 2010 |
The use of carbonic anhydrase inhibitors in the retreatment of cystic macular lesions in retinitis pigmentosa and X-linked retinoschisis.
Topics: Acetazolamide; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Retinitis Pigmentosa; Retinoschisis; Retreatment; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Usher Syndromes; Visual Acuity | 2011 |
Electrophysiological consequences of experimental branch retinal vein occlusion in pigs and the effect of dorzolamide.
Topics: Animals; Carbonic Anhydrase Inhibitors; Electroretinography; Female; Fluorescein Angiography; Ophthalmoscopy; Photography; Reperfusion Injury; Retina; Retinal Vein Occlusion; Retinal Vessels; Sulfonamides; Swine; Thiophenes | 2011 |
The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.
Topics: Adult; Antihypertensive Agents; Blindness; Brimonidine Tartrate; Decision Trees; Disease Progression; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Biological; Monte Carlo Method; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol | 2011 |
Ability of dorzolamide hydrochloride and timolol maleate to target mitochondria in glaucoma therapy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Autoradiography; Cell Line; Chromatography, Thin Layer; Deoxyguanosine; DNA Fragmentation; Glaucoma, Open-Angle; Humans; Hydrogen Peroxide; Mitochondria; Oxidative Stress; Sulfonamides; Thiophenes; Timolol; Tissue Donors; Trabecular Meshwork | 2011 |
A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug.
Topics: Animals; Antihypertensive Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Cornea; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Glaucoma; Polyesters; Polymers; Porosity; Rabbits; Regression Analysis; Sulfonamides; Tetrazolium Salts; Thiazoles; Thiophenes; X-Ray Diffraction | 2011 |
[Comparison of primary medicament therapy effects and primary argon laser trabeculoplasty on regulation of intraocular pressure and stability of perimetry findings in open angle glaucoma].
Topics: Aged; Antihypertensive Agents; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Lasers, Gas; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Visual Field Tests | 2011 |
X-linked retinoschisis maculopathy treated with topical dorzolamide, and relationship to genotype.
Topics: Administration, Topical; Adolescent; Adult; Child; Eye Proteins; Female; Genetic Diseases, X-Linked; Genotype; Humans; Macula Lutea; Male; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity; Young Adult | 2011 |
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.
Topics: Animals; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Disease Models, Animal; Glaucoma; Humans; Models, Molecular; Molecular Structure; Nitric Oxide; Ocular Hypertension; Protein Isoforms; Rabbits; Sulfonamides; Thiophenes | 2011 |
In vitro and in vivo evaluation of an intraocular implant for glaucoma treatment.
Topics: Animals; Antihypertensive Agents; Calorimetry, Differential Scanning; Drug Carriers; Drug Implants; Eye; Glaucoma; Intraocular Pressure; Kinetics; Microscopy, Electron, Scanning; Polyesters; Polyethylene Glycols; Propylene Glycols; Rabbits; Solubility; Sulfonamides; Surface Properties; Thiophenes | 2011 |
Ocular pharmacokinetics of dorzolamide and brinzolamide after single and multiple topical dosing: implications for effects on ocular blood flow.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Chromatography, Liquid; Drug Administration Schedule; Eye; Male; Optic Nerve; Rabbits; Regional Blood Flow; Sulfonamides; Tandem Mass Spectrometry; Thiazines; Thiophenes | 2011 |
A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology.
Topics: Acrylic Resins; Animals; Carbonic Anhydrases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glaucoma; Isosorbide Dinitrate; Male; Molecular Structure; Nitrates; Nitric Oxide; Rabbits; Sulfonamides; Thiophenes; Time Factors | 2012 |
Topical dorzolamide for treatment of cystoid macular edema in patients with choroideremia.
Topics: Carbonic Anhydrase Inhibitors; Choroideremia; Contrast Sensitivity; Humans; Macular Edema; Male; Middle Aged; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Visual Field Tests | 2012 |
The effect of dorzolamide 2% on circadian intraocular pressure in cats with primary congenital glaucoma.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Cat Diseases; Cats; Circadian Rhythm; Female; Glaucoma; Intraocular Pressure; Male; Sulfonamides; Thiophenes | 2011 |
The clinical efficacy of a topical dorzolamide in the management of cystoid macular edema in patients with retinitis pigmentosa.
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Retina; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Visual Field Tests; Visual Fields; Young Adult | 2012 |
The long-term outcomes of four alternative treatment strategies for primary open-angle glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cost-Benefit Analysis; Decision Support Techniques; Disease Progression; Drug Costs; Economics, Pharmaceutical; Follow-Up Studies; Glaucoma, Open-Angle; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quality-Adjusted Life Years; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2012 |
The effects of a fixed combination of 0.5% timolol and 1% dorzolamide on optic nerve head blood circulation.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Synergism; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Optic Disk; Perfusion; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Young Adult | 2012 |
A novel and rapid validated stability-indicating UPLC method of related substances for dorzolamide hydrochloride and timolol maleate in ophthalmic dosage form.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Contamination; Drug Stability; Hydrogen-Ion Concentration; Linear Models; Models, Molecular; Ophthalmic Solutions; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Thiophenes; Timolol | 2012 |
Retrobulbar hemodynamics before and after oculopression with and without dorzolamide.
Topics: Administration, Topical; Aged; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Tonometry, Ocular; Ultrasonography, Doppler, Color | 2012 |
In vivo imaging reveals novel aspects of retinal disease progression in Rs1h(-/Y) mice but no therapeutic effect of carbonic anhydrase inhibition.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cell Adhesion Molecules; Eye Proteins; Gene Deletion; Gene Expression Regulation; Male; Mice; Ophthalmic Solutions; Retina; Retinoschisis; Sulfonamides; Thiophenes | 2012 |
Effects of ocular administration of ophthalmic 2% dorzolamide hydrochloride solution on aqueous humor flow rate and intraocular pressure in clinically normal cats.
Topics: Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cats; Female; Fluorophotometry; Intraocular Pressure; Linear Models; Male; Ophthalmic Solutions; Random Allocation; Sulfonamides; Thiophenes; Tonometry, Ocular | 2012 |
Regulation of retinal proteome by topical antiglaucomatous eye drops in an inherited glaucoma rat model.
Topics: Animals; Calmodulin; Carbonic Anhydrase II; Cloprostenol; Disease Models, Animal; Glaucoma; HMGB1 Protein; HSP70 Heat-Shock Proteins; Intraocular Pressure; Ophthalmic Solutions; Peptide Mapping; Proteome; Proteomics; Rats; Retina; Sulfonamides; Thiophenes; Travoprost | 2012 |
Dorzolamide-induced relaxation of intraocular porcine ciliary arteries in vitro depends on nitric oxide and the vascular endothelium.
Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isometric Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxadiazoles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Sulfonamides; Swine; Thiazines; Thiophenes; Vasodilation; Vasodilator Agents | 2012 |
[The rabbit's IOP values after instillation of the L-arginine HCL with selected antiglaucomatic drugs mixtures prepared in vitro. (comparative study of results of the experimental works)].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2012 |
Topical dorzolamide therapy for taxane-related macular oedema.
Topics: Administration, Topical; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Female; Humans; Macular Edema; Middle Aged; Paclitaxel; Sulfonamides; Thiophenes; Treatment Outcome | 2013 |
Topical dorzolamide treatment of macular cysts in the enhanced S-cone syndrome patient.
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Cysts; Electroretinography; Eye Diseases, Hereditary; Follow-Up Studies; Humans; Macular Edema; Male; Ophthalmic Solutions; Retinal Degeneration; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Visual Acuity | 2013 |
Preparation of a molecularly imprinted soft contact lens as a new ocular drug delivery system for dorzolamide.
Topics: Administration, Ophthalmic; Adsorption; Carbonic Anhydrase Inhibitors; Contact Lenses, Hydrophilic; Drug Delivery Systems; Hydrogels; Methacrylates; Molecular Imprinting; Sulfonamides; Thiophenes | 2013 |
Congenital glaucoma with acquired peripheral circumferential iris degeneration.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Drug Therapy, Combination; Eye Abnormalities; Female; Forkhead Transcription Factors; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Iris; Point Mutation; Sequence Deletion; Sulfonamides; Thiophenes; Timolol | 2013 |
Evaluation of adverse events in self-reported sulfa-allergic patients using topical carbonic anhydrase inhibitors.
Topics: Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cohort Studies; Drug Hypersensitivity; Female; Glaucoma; Humans; Male; Middle Aged; Prostaglandins; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes | 2013 |
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A | 2013 |
Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide.
Topics: Adult; Carbonic Anhydrase Inhibitors; Cysts; Electroretinography; Eye Proteins; Humans; Male; Mutation, Missense; Polymerase Chain Reaction; Retinal Diseases; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence | 2014 |
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular | 2013 |
Therapeutic effect of prolonged treatment with topical dorzolamide for cystoid macular oedema in patients with retinitis pigmentosa.
Topics: Administration, Topical; Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Middle Aged; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Time Factors; Tomography, Optical Coherence; Young Adult | 2013 |
[Contribution focused to clarify correlation between mixtures of the free amino acids with antiglaucomatics in influencing the IOP in rabbits after application into the conjunctival sac].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2013 |
A decrease of the rabbit's physiologic IOP after the application of specific amino acids and double combination of antiglaucomatics mixture.
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Taurine; Thiophenes; Timolol | 2013 |
Efficacy of prophylactic antiglaucoma and anti-inflammatory medications in canine primary angle-closure glaucoma: a multicenter retrospective study (2004-2012).
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Quaternary Ammonium Compounds; Retrospective Studies; Sulfonamides; Thiophenes | 2014 |
Sarcoidosis patient: an unexpected reaction to carbonic anhydrase enzyme inhibitor.
Topics: Carbonic Anhydrase Inhibitors; Eye Diseases; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Sarcoidosis; Sulfonamides; Thiophenes | 2013 |
Design and in vitro characterization of small unilamellar niosomes as ophthalmic carrier of dorzolamide hydrochloride.
Topics: Chemistry, Pharmaceutical; Cholesterol; Drug Carriers; Drug Delivery Systems; Hexoses; Liposomes; Ophthalmic Solutions; Organophosphates; Particle Size; Polyethylene Glycols; Sulfonamides; Surface-Active Agents; Thiophenes | 2014 |
Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Topics: Antigens, Neoplasm; Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Crystallography, X-Ray; Humans; Kinetics; Molecular Docking Simulation; Mutagenesis, Site-Directed; Protein Binding; Structure-Activity Relationship; Sulfonamides; Thermodynamics; Thiazines; Thiophenes | 2013 |
Serous retinal detachment and cystoid macular edema in a patient with Wyburn-Mason syndrome.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arteriovenous Fistula; Drug Therapy, Combination; Fluorescein Angiography; Glucocorticoids; Humans; Ketorolac Tromethamine; Macular Edema; Magnetic Resonance Imaging; Male; Neurocutaneous Syndromes; Prednisolone; Retinal Detachment; Subretinal Fluid; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Triamcinolone Acetonide | 2015 |
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Drug Therapy, Combination; Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Hypertension; Miotics; Mydriasis; Ocular Hypertension; Pilocarpine; Prostaglandins F; Quinoxalines; Sulfonamides; Syndrome; Thiophenes; Timolol | 2013 |
[Signs and symptoms of ocular surface disease in patients on topical intraocular pressure-lowering therapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blepharitis; Cornea; Cross-Sectional Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Lacrimal Apparatus Diseases; Male; Microscopy, Acoustic; Middle Aged; Ocular Hypertension; Severity of Illness Index; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Young Adult | 2013 |
A combination of topical and systemic carbonic anhydrase in the treatment of chromosome X-linked retinoschisis.
Topics: Acetazolamide; Administration, Topical; Adolescent; Carbonic Anhydrase Inhibitors; Humans; Male; Retinoschisis; Sulfonamides; Thiophenes | 2014 |
Removal of dorzolamide from biomedical wastewaters with adsorption onto graphite oxide/poly(acrylic acid) grafted chitosan nanocomposite.
Topics: Acrylic Resins; Adsorption; Chitosan; Graphite; Hydrogen-Ion Concentration; Medical Waste; Nanocomposites; Oxides; Solutions; Spectroscopy, Fourier Transform Infrared; Sulfonamides; Thiophenes; Wastewater; Water Pollutants, Chemical | 2014 |
Development and characterization of nano-fiber patch for the treatment of glaucoma.
Topics: Animals; Antihypertensive Agents; Drug Delivery Systems; Glaucoma; Nanofibers; Rabbits; Sulfonamides; Thiophenes; Timolol | 2014 |
[Current trend of glaucoma medication with various eye drops].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Glaucoma; Humans; Latanoprost; Neuroprotective Agents; Ophthalmic Solutions; Ophthalmology; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 2013 |
In situ gelling dorzolamide loaded chitosan nanoparticles for the treatment of glaucoma.
Topics: Animals; Calorimetry, Differential Scanning; Carbonic Anhydrase Inhibitors; Chitosan; Glaucoma; Goats; Humans; In Vitro Techniques; Nanoparticles; Radionuclide Imaging; Sulfonamides; Thiophenes; X-Ray Diffraction | 2014 |
Retinal Dystrophy with Intraretinal Cystoid Spaces Associated with Mutations in the Crumbs Homologue (CRB1) Gene.
Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Eye Proteins; Female; Humans; Macular Edema; Male; Membrane Proteins; Mutation; Nerve Tissue Proteins; Pedigree; Polymerase Chain Reaction; Retinal Dystrophies; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2015 |
Novel spectrophotometric methods for simultaneous determination of timolol and dorzolamide in their binary mixture.
Topics: Antihypertensive Agents; Drug Combinations; Spectrophotometry; Sulfonamides; Thiophenes; Timolol | 2014 |
Dorzolamide cyclodextrin nanoparticle suspension eye drops and Trusopt in rabbit.
Topics: Animals; Carbonic Anhydrase Inhibitors; Delayed-Action Preparations; Drug Delivery Systems; gamma-Cyclodextrins; Harderian Gland; Inflammation; Nanoparticles; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes | 2014 |
A prospective research study of anti-glaucoma drugs prescribing, utilization pattern and adverse drug reaction recording in a university hospital.
Topics: Acetazolamide; Adult; Adverse Drug Reaction Reporting Systems; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; Glaucoma; Hospitals, University; Humans; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2015 |
Medical management of acute ocular hypertension in a western screech owl (Megascops kennicottii).
Topics: Acute Disease; Animals; Bird Diseases; Carbonic Anhydrase Inhibitors; Diclofenac; Mannitol; Meloxicam; Ocular Hypertension; Strigiformes; Sulfonamides; Thiazines; Thiazoles; Thiophenes | 2014 |
Dorzolamide-loaded PLGA/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Ocular Hypertension; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Radionuclide Imaging; Sulfonamides; Thiophenes; Vitamin A; Vitamin E | 2014 |
Simultaneous determination of dorzolomide and timolol in aqueous humor: a novel salting out liquid-liquid microextraction combined with HPLC.
Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Limit of Detection; Liquid Phase Microextraction; Male; Rabbits; Solvents; Sulfonamides; Thiophenes; Timolol; Tissue Distribution | 2014 |
Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells.
Topics: Acidosis; Animals; Arterioles; Benzopyrans; Bradykinin; Carbonic Anhydrase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Lactates; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasodilation | 2014 |
Efficacy of topical dorzolamide therapy for cystoid macular edema in a patient with MFRP-related nanophthalmos-retinitis pigmentosa-foveoschisis-optic disk drusen syndrome.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Female; Frameshift Mutation; Humans; Macular Edema; Membrane Proteins; Microphthalmos; Middle Aged; Optic Disk Drusen; Retinitis Pigmentosa; Sulfonamides; Syndrome; Thiophenes; Treatment Outcome | 2015 |
Mechanisms of human erythrocytic bioactivation of nitrite.
Topics: Blood Platelets; Carbonic Anhydrases; Electron Spin Resonance Spectroscopy; Erythrocytes; Hemoglobins; Humans; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidation-Reduction; Signal Transduction; Sulfonamides; Thiophenes | 2015 |
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol | 2015 |
Detection of protein-small molecule binding using a self-referencing external cavity laser biosensor.
Topics: Biosensing Techniques; Carbonic Anhydrase II; Enzymes, Immobilized; Humans; Indoles; Lasers; Protein Binding; Serum Albumin; Small Molecule Libraries; Sulfonamides; Thiophenes; Warfarin | 2014 |
Totally one-sided: painless unilateral proptosis.
Topics: Aged, 80 and over; Antihypertensive Agents; Arteriovenous Fistula; Brimonidine Tartrate; Carotid Artery, Internal; Cavernous Sinus; Cerebral Angiography; Diagnosis, Differential; Exophthalmos; Female; Humans; Intraocular Pressure; Levobunolol; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Tomography, X-Ray Computed; Treatment Outcome; Vision Disorders | 2015 |
Efficacy and prognostic factors of response to carbonic anhydrase inhibitors in management of cystoid macular edema in retinitis pigmentosa.
Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Cohort Studies; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome | 2015 |
Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure.
Topics: Animals; Carbonic Anhydrase Inhibitors; Drug Design; Glaucoma; Intraocular Pressure; Male; Nitric Oxide Donors; Rabbits; Sulfonamides; Thiazines; Thiophenes | 2015 |
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Molecular Sequence Data; Nostoc commune; Sequence Alignment; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines; Thiophenes | 2015 |
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.
Topics: Animals; Antihypertensive Agents; Carbon Disulfide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Male; Molecular Docking Simulation; Morpholines; Piperazines; Piperidines; Quinuclidines; Rabbits; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Thiocarbamates; Thiophenes | 2015 |
Retinal vein-to-vein anastomoses in Sturge-Weber syndrome documented by ultra-widefield fluorescein angiography.
Topics: Carbonic Anhydrase Inhibitors; Child; Fluorescein Angiography; Glaucoma; Humans; Intraocular Pressure; Male; Retinal Vein; Sturge-Weber Syndrome; Sulfonamides; Thiophenes; Vascular Fistula; Visual Acuity | 2015 |
Dual drug delivery from vitamin E loaded contact lenses for glaucoma therapy.
Topics: Animals; Antihypertensive Agents; Biological Availability; Contact Lenses; Delayed-Action Preparations; Dogs; Drug Liberation; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Vitamin E | 2015 |
Spectroscopic and molecular modeling studies on binding of dorzolamide to bovine and human carbonic anhydrase II.
Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Catalytic Domain; Cattle; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Spectrum Analysis; Substrate Specificity; Sulfonamides; Thermodynamics; Thiophenes | 2015 |
Dorzolamide synergizes the antitumor activity of mitomycin C against Ehrlich's carcinoma grown in mice: role of thioredoxin-interacting protein.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Carrier Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Mitomycin; Sulfonamides; Thiophenes; Thioredoxins | 2015 |
CRB1-Related Maculopathy With Cystoid Macular Edema.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Diseases in Twins; DNA Mutational Analysis; Electroretinography; Eye Proteins; Female; Fluorescein Angiography; Humans; Macular Edema; Membrane Proteins; Mutation; Nerve Tissue Proteins; Ophthalmic Solutions; Retinal Dystrophies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Twins, Monozygotic; Visual Acuity | 2015 |
The effect of prophylactic topical carbonic anhydrase inhibitors in canine primary closed-angle glaucoma.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2015 |
Rapid and selective removal of preservative from ophthalmic formulations during eyedrops instillation.
Topics: Antihypertensive Agents; Benzalkonium Compounds; Drug Packaging; Hydrogels; Hydrophobic and Hydrophilic Interactions; Ophthalmic Solutions; Permeability; Polyhydroxyethyl Methacrylate; Preservatives, Pharmaceutical; Sterilization; Sulfonamides; Thiophenes; Timolol | 2015 |
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Topics: Acid-Base Imbalance; Acidosis, Renal Tubular; Aged; Air Pollution, Indoor; Amino Acid Substitution; Animals; Animals, Newborn; Anti-Bacterial Agents; Antibodies, Neutralizing; Apoptosis; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Bone Marrow Transplantation; Carbonic Anhydrase Inhibitors; Castleman Disease; Cat Diseases; Cats; Cell Proliferation; Cell- and Tissue-Based Therapy; Chemical and Drug Induced Liver Injury; Chemotaxis, Leukocyte; Clinical Trials as Topic; Coated Materials, Biocompatible; Diagnosis, Differential; Disease Models, Animal; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Genotype; Granuloma, Foreign-Body; Heart Failure; Hepacivirus; Hepatitis C; Horse Diseases; Horses; Housing; Humans; Hypercalcemia; Hypokalemia; Immunophenotyping; In Vitro Techniques; Liver; Liver Function Tests; Lymphocytes; Macrophages; Male; Medicine, Chinese Traditional; Metabolomics; Mice; Mice, Inbred C57BL; Middle Aged; Models, Animal; Mutation; Myocardial Ischemia; Neovascularization, Physiologic; Neutrophil Infiltration; Ocular Hypertension; Ophthalmic Solutions; Parathyroid Hormone; Particulate Matter; Polyethylene Terephthalates; Prednisolone; Prospective Studies; Prosthesis Design; Prosthesis-Related Infections; Rats; Rats, Wistar; Reactive Oxygen Species; Rifampin; Saponins; Sepsis; Skin; Stem Cells; Stroke Volume; Sulfonamides; Texas; Thiophenes; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Viral Hepatitis Vaccines; Viral Nonstructural Proteins; Viral Proteins; Vitamin D; Wound Healing | 2015 |
Keratitis in six dogs after topical treatment with carbonic anhydrase inhibitors for glaucoma.
Topics: Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma; Keratitis; Male; Sulfonamides; Thiazines; Thiophenes | 2015 |
Dorzolamide-induced relaxation of isolated rabbit ciliary arteries mediated by inhibition of extracellular calcium influx.
Topics: Animals; Calcium; Calcium Channels; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Space; Fluorophotometry; Isometric Contraction; Muscle, Smooth, Vascular; Optic Nerve; Potassium; Rabbits; Sulfonamides; Thiophenes; Vasodilation; Vasodilator Agents | 2016 |
Fundus Autofluorescence and SD-OCT Document Rapid Progression in Autosomal Dominant Vitreoretinochoroidopathy (ADVIRC) Associated with a c.256G > A Mutation in BEST1.
Topics: Adult; Bestrophins; Carbonic Anhydrase Inhibitors; Child; Chloride Channels; Choroid Diseases; Disease Progression; Electroretinography; Eye Diseases, Hereditary; Eye Proteins; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Genes, Dominant; Humans; Macular Edema; Male; Middle Aged; Mutation, Missense; Optical Imaging; Pedigree; Polymerase Chain Reaction; Retinal Degeneration; Sequence Analysis, DNA; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2016 |
Secondary pigmentary glaucoma associated with 1-piece foldable intraocular lens in the ciliary sulcus.
Topics: Aged, 80 and over; Antihypertensive Agents; Ciliary Body; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Phacoemulsification; Prosthesis Design; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Tonometry, Ocular; Visual Acuity | 2015 |
Cystoid macular lesions are resistant to topical dorzolamide treatment in enhanced S-cone syndrome child.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Electroretinography; Eye Diseases, Hereditary; Fluorescein Angiography; Humans; Macular Edema; Male; Ophthalmic Solutions; Retina; Retinal Degeneration; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Visual Acuity | 2016 |
Effects of dorzolamide/timolol fixed combination on retrobulbar hemodynamics in pseudoexfoliative glaucoma.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Exfoliation Syndrome; Eye; Female; Hemodynamics; Humans; Male; Middle Aged; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2016 |
Topical carbonic anhydrase inhibitors in macular edema associated with Alström syndrome.
Topics: Administration, Topical; Alstrom Syndrome; Carbonic Anhydrase Inhibitors; Cell Cycle Proteins; Female; Humans; Infant; Macular Edema; Ophthalmic Solutions; Proteins; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2016 |
Macular cystoid spaces in patients with retinal dystrophy.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Child; DNA Mutational Analysis; Eye Proteins; Female; Humans; Macular Edema; Male; Middle Aged; Retinal Dystrophies; Retrospective Studies; Sulfonamides; Thiophenes; Visual Acuity | 2016 |
Effects of Dorzolamide on Retinal and Choroidal Blood Flow in the DBA/2J Mouse Model of Glaucoma.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Choroid; Disease Models, Animal; Glaucoma; Intraocular Pressure; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Treatment Outcome | 2016 |
Single-eye trial of a topical carbonic anhydrase inhibitor versus intravitreal bevacizumab for the treatment of taxane drug-induced cystoid macula oedema.
Topics: Administration, Topical; Aged; Angiogenesis Inhibitors; Bevacizumab; Bridged-Ring Compounds; Carbonic Anhydrase Inhibitors; Humans; Intravitreal Injections; Macular Edema; Male; Sulfonamides; Taxoids; Thiophenes | 2016 |
Efficacy of Bimatoprost Plus Timolol Fixed Combination in Open Angle Glaucoma Patients Previously Treated with Dorzolamide Plus Timolol Fixed Combination.
Topics: Aged; Antihypertensive Agents; Bimatoprost; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2016 |
In vitro and in vivo corneal effects of latanoprost combined with brimonidine, timolol, dorzolamide, or brinzolamide.
Topics: Animals; Brimonidine Tartrate; Cell Survival; Electric Impedance; Epithelium, Corneal; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol | 2016 |
Dramatic regression of macular and peripheral retinoschisis with dorzolamide 2 % in X-linked retinoschisis: a case report.
Topics: Carbonic Anhydrase Inhibitors; Humans; Infant; Male; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome | 2016 |
Subconjunctival Delivery of Dorzolamide-Loaded Poly(ether-anhydride) Microparticles Produces Sustained Lowering of Intraocular Pressure in Rabbits.
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Ethylamines; Female; Glaucoma; Intraocular Pressure; Lactic Acid; Male; Oleic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Sodium Dodecyl Sulfate; Sulfonamides; Thiophenes | 2016 |
Aqueous Flow Measured by Fluorophotometry in the Mouse.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Anesthetics, Dissociative; Animals; Anterior Chamber; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cornea; Ethanol; Female; Fluorescein; Fluorescent Dyes; Fluorophotometry; Hypnotics and Sedatives; Ketamine; Male; Mice; Organ Size; Sulfonamides; Thiophenes; Timolol; Xylazine | 2016 |
New Electrochemically-Modified Carbon Paste Inclusion β-Cyclodextrin and Carbon Nanotubes Sensors for Quantification of Dorzolamide Hydrochloride.
Topics: beta-Cyclodextrins; Biosensing Techniques; Calibration; Carbon; Electrochemistry; Hydrogen-Ion Concentration; Limit of Detection; Nanotubes, Carbon; Ophthalmic Solutions; Plasticizers; Reproducibility of Results; Sulfonamides; Temperature; Thiophenes; Time Factors | 2016 |
Maximizing cost-effectiveness by adjusting treatment strategy according to glaucoma severity.
Topics: Age Factors; Antihypertensive Agents; Brazil; Cost-Benefit Analysis; Glaucoma, Open-Angle; Health Care Costs; Humans; Lasers, Gas; Markov Chains; Prostaglandins; Quality of Life; Quality-Adjusted Life Years; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Watchful Waiting | 2016 |
Effect of prophylactic topical hypotensive medications in reducing the incidence of postoperative ocular hypertension after phacoemulsification in dogs.
Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Female; Incidence; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Pre-Exposure Prophylaxis; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2017 |
Enhanced ocular efficacy of topically-delivered dorzolamide with nanostructured mucoadhesive microparticles.
Topics: Adhesives; Administration, Ophthalmic; Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Drug Compounding; Intraocular Pressure; Lactic Acid; Male; Mucous Membrane; Nanofibers; Ophthalmic Solutions; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propylene Glycol; Rabbits; Solubility; Sulfonamides; Thiophenes | 2017 |
STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS: RESPONSE TO TOPICAL DORZOLAMIDE THERAPY.
Topics: Adult; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Fluorescein Angiography; Fovea Centralis; Fundus Oculi; Humans; Macula Lutea; Male; Ophthalmic Solutions; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity | 2019 |
Carbonic Anhydrase Inhibitors Induce Developmental Toxicity During Zebrafish Embryogenesis, Especially in the Inner Ear.
Topics: Acetazolamide; Animal Fins; Animals; Apoptosis; Calcium; Carbonic Anhydrase Inhibitors; Cardiomegaly; Ear, Inner; Embryo, Nonmammalian; Embryonic Development; Ethoxzolamide; Hair Cells, Auditory; Otolithic Membrane; Sulfonamides; Swimming; Thiophenes; Zebrafish | 2017 |
Validated HPLC-DAD Method for the Simultaneous Determination of Six Selected Drugs Used in the Treatment of Glaucoma.
Topics: Acetazolamide; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Glaucoma; Humans; Levobunolol; Sulfonamides; Thiophenes; Timolol | 2018 |
Isotretinoin-induced Angle Closure and Myopic Shift.
Topics: Acne Vulgaris; Adult; Antihypertensive Agents; Dermatologic Agents; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Isotretinoin; Microscopy, Acoustic; Myopia; Sulfonamides; Thiophenes; Timolol | 2017 |
The application of artificial neural networks and support vector regression for simultaneous spectrophotometric determination of commercial eye drop contents.
Topics: Humans; Neural Networks, Computer; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Sulfonamides; Support Vector Machine; Thiophenes; Timolol | 2018 |
Metabolic acidosis and anaemia associated with dorzolamide in a patient with impaired renal function.
Topics: Acidosis; Administration, Ophthalmic; Anemia; Carbonic Anhydrase Inhibitors; Fatigue; Glaucoma; Humans; Male; Middle Aged; Renal Insufficiency; Sulfonamides; Thiophenes | 2018 |
Treatment of cystoid macular edema in homozygous twins with glutathione synthetase deficiency and retinal dystrophy.
Topics: Acetazolamide; Administration, Oral; Amino Acid Metabolism, Inborn Errors; Child; Combined Modality Therapy; Diseases in Twins; Drug Therapy, Combination; Glutathione Synthase; Humans; Macular Edema; Male; Ophthalmic Solutions; Retinal Dystrophies; Sulfonamides; Thiophenes | 2018 |
Enhancement of pharmacokinetic and pharmacological behavior of ocular dorzolamide after factorial optimization of self-assembled nanostructures.
Topics: Animals; Aqueous Humor; Biological Availability; Delayed-Action Preparations; Drug Compounding; Glaucoma; Half-Life; Intraocular Pressure; Male; Nanostructures; Ophthalmic Solutions; Particle Size; Permeability; Phosphatidylcholines; Rabbits; Sulfonamides; Thiophenes | 2018 |
Paradoxical Anatomic Response to Topical Carbonic Anhydrase Inhibitor in X-linked Retinoschisis.
Topics: Carbonic Anhydrase Inhibitors; Child; Humans; Macula Lutea; Male; Retinoschisis; Sulfonamides; Thiophenes | 2018 |
Retrospective cohort study exploring whether an association exists between spatial distribution of cystoid spaces in cystoid macular oedema secondary to retinitis pigmentosa and response to treatment with carbonic anhydrase inhibitors.
Topics: Acetazolamide; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Middle Aged; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Tomography, Optical Coherence; Visual Acuity; Visual Field Tests; Young Adult | 2019 |
Effect of topical dorzolamide therapy on cystoid macular edema in hydroxychloroquine retinopathy.
Topics: Administration, Topical; Adult; Aged; Antirheumatic Agents; Carbonic Anhydrase Inhibitors; Female; Fluorescein Angiography; Fundus Oculi; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Macular Edema; Retinal Diseases; Sulfonamides; Thiophenes; Visual Acuity | 2018 |
Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic evaluation in rabbits.
Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Cholesterol; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Eye; Gels; Glaucoma; Intraocular Pressure; Liposomes; Male; Ophthalmic Solutions; Particle Size; Rabbits; Sulfonamides; Surface-Active Agents; Thiophenes | 2018 |
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjunctivitis, Allergic; Cyclopentolate; Drug Therapy, Combination; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Granuloma; Humans; Latanoprost; Lubricant Eye Drops; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Sulfonamides; Thiophenes; Timolol; Uveitis, Anterior | 2018 |
TOPICAL DORZOLAMIDE FOR CYSTOID MACULAR EDEMA IN BIETTI CRYSTALLINE RETINAL DYSTROPHY.
Topics: Administration, Ophthalmic; Adult; Carbonic Anhydrase Inhibitors; Corneal Dystrophies, Hereditary; Female; Humans; Macular Edema; Multimodal Imaging; Ophthalmic Solutions; Retinal Diseases; Sulfonamides; Thiophenes; Visual Acuity | 2021 |
Metabolic acidosis during general anaesthesia: presumed systemic toxicity caused by topical dorzolamide in a dog.
Topics: Acidosis; Administration, Topical; Anesthesia, General; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma; Sulfonamides; Thiophenes | 2018 |
A Novel Method to Eliminate Preservatives in Eye Drops.
Topics: Anti-Bacterial Agents; Bacteria; Humans; Microbial Sensitivity Tests; Moxifloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Sulfonamides; Thiophenes; Timolol | 2018 |
Generalised nevus flammeus, episcleral capillary malformation and glaucoma.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Adult; Capillaries; Carbonic Anhydrase Inhibitors; Cryosurgery; Diagnosis, Differential; Female; Glaucoma; Humans; Port-Wine Stain; Sulfonamides; Thiophenes; Timolol; Vascular Malformations | 2018 |
Double trouble: exudative hypertensive retinopathy in a patient with retinitis pigmentosa.
Topics: Adult; Anti-Inflammatory Agents; Antihypertensive Agents; Diagnosis, Differential; Female; Fluorescein Angiography; Humans; Hypertensive Retinopathy; Retina; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Triamcinolone Acetonide; Young Adult | 2018 |
Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal Arteries.
Topics: Acetazolamide; Animals; Benzolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Muscle, Smooth, Vascular; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasodilation | 2019 |
Topical Aqueous Suppression and Closure of Idiopathic Full-Thickness Macular Holes.
Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Humans; Male; Middle Aged; Retinal Perforations; Sulfonamides; Thiophenes; Treatment Outcome | 2019 |
A versatile HPLC method with an isocratic single mobile phase system for simultaneous determination of anti-glaucoma formulations containing timolol.
Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Chromatography, High Pressure Liquid; Drug Combinations; Drug Compounding; Glaucoma; Limit of Detection; Ophthalmic Solutions; Reference Standards; Reproducibility of Results; Sulfonamides; Thiazines; Thiophenes; Timolol | 2019 |
Corneal sterile infiltration induced by topical use of ocular hypotensive agent.
Topics: Aged; Antihypertensive Agents; Bimatoprost; Blepharitis; Brimonidine Tartrate; Conjunctivitis; Corneal Neovascularization; Corneal Opacity; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Low Tension Glaucoma; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Thiophenes | 2020 |
Designing of a pH-Triggered Carbopol®/HPMC In Situ Gel for Ocular Delivery of Dorzolamide HCl: In Vitro, In Vivo, and Ex Vivo Evaluation.
Topics: Acrylic Resins; Administration, Ophthalmic; Animals; Antihypertensive Agents; Cornea; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Gels; Glaucoma; Hydrogen-Ion Concentration; Hypromellose Derivatives; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Sulfonamides; Swine; Thiophenes | 2019 |
Effect of topical glaucoma medication on tear lipid layer thickness in patients with unilateral glaucoma.
Topics: Administration, Ophthalmic; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Sectional Studies; Drug Combinations; Dry Eye Syndromes; Female; Gonioscopy; Humans; Interferometry; Intraocular Pressure; Lipid Metabolism; Low Tension Glaucoma; Male; Meibomian Gland Dysfunction; Middle Aged; Ophthalmic Solutions; Sulfonamides; Tears; Thiophenes; Timolol; Tonometry, Ocular | 2019 |
Pigmented paravenous retinochoroidal atrophy associated with unilateral cystoid macular oedema.
Topics: Aged; Angiogenesis Inhibitors; Bevacizumab; Carbonic Anhydrase Inhibitors; Eye Diseases, Hereditary; Fluorescein Angiography; Humans; Injections, Intraocular; Macular Edema; Male; Retinal Degeneration; Sulfonamides; Thiophenes; Tomography, Optical Coherence | 2019 |
Leucaena leucocephala (Lam.) galactomannan nanoparticles: Optimization and characterization for ocular delivery in glaucoma treatment.
Topics: Adhesiveness; Animals; Drug Carriers; Drug Liberation; Eye; Fabaceae; Galactose; Glaucoma; Goats; Mannans; Nanoparticles; Permeability; Sulfonamides; Thiophenes | 2019 |
Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide for glaucoma treatment: In vitro and in vivo evaluation.
Topics: Animals; Cellulose; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Eye; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Polymers; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Tissue Distribution | 2019 |
Bilateral giant macular schisis in a case of Goldmann-Favre syndrome.
Topics: Antihypertensive Agents; Diagnosis, Differential; Electroretinography; Eye Diseases, Hereditary; Humans; Macula Lutea; Male; Night Blindness; Retinal Degeneration; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Young Adult | 2019 |
Effect of Formulation Variables and Gamma Sterilization on Transcorneal Permeation and Stability of Proniosomal Gels as Ocular Platforms for Antiglaucomal Drug.
Topics: Animals; Cornea; Drug Compounding; Drug Stability; Gamma Rays; Gels; Glaucoma; Liposomes; Male; Permeability; Rabbits; Sterilization; Sulfonamides; Thiophenes | 2020 |
Reversible Corneal Endothelial Abnormalities With Netarsudil.
Topics: Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Remission Induction; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Withholding Treatment | 2020 |
Are P Values Enough?
Topics: Humans; Macular Degeneration; Sulfonamides; Thiophenes; Timolol | 2020 |
The Carbonic Anhydrase Inhibitor Dorzolamide Stimulates the Differentiation of Human Meibomian Gland Epithelial Cells.
Topics: Biomarkers; Carbonic Anhydrase Inhibitors; Cell Differentiation; Cell Proliferation; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Humans; Immunoblotting; Lipid Metabolism; Lysosomes; Meibomian Glands; Phospholipids; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides; Thiophenes | 2020 |
Effect of Topical Dorzolamide on Cystoid Macular Edema in Retinitis Pigmentosa.
Topics: Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Macula Lutea; Macular Edema; Male; Ophthalmic Solutions; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity | 2020 |
Dramatic response to topical dorzolamide in X-linked retinoschisis.
Topics: Humans; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence | 2020 |
Allergic contact dermatitis due to dorzolamide eyedrops.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dermatitis, Allergic Contact; Eyelids; Facial Dermatoses; Female; Humans; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2021 |
Prophylactic anti-glaucoma therapy in dogs with primary glaucoma: A practitioner survey of current medical protocols.
Topics: Animals; Dog Diseases; Dogs; Female; Glaucoma; Health Care Surveys; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2021 |
Optimization to development of chitosan decorated polycaprolactone nanoparticles for improved ocular delivery of dorzolamide: In vitro, ex vivo and toxicity assessments.
Topics: Administration, Ophthalmic; Animals; Chitosan; Drug Compounding; Drug Delivery Systems; Nanoparticles; Particle Size; Polyesters; Sulfonamides; Thiophenes | 2020 |
Animal model of assessing cerebrovascular functional reserve by imaging photoplethysmography.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Cerebrovascular Disorders; Heart Rate; Male; Models, Animal; Photoplethysmography; Rats, Wistar; Sulfonamides; Thiophenes | 2020 |
Necrotising fungal scleritis with full-thickness scleral melt and circumferential progression: a novel debridement approach.
Topics: Adrenal Cortex Hormones; Adult; Agaricales; Antifungal Agents; Diagnosis, Differential; Disease Progression; Eye Infections, Fungal; Eye Pain; Female; Humans; Scleritis; Sulfonamides; Thiophenes; Timolol | 2020 |
Resolution of bilateral foveal cysts in dome-shaped macula after treatment with topical dorzolamide.
Topics: Administration, Ophthalmic; Carbonic Anhydrase Inhibitors; Child, Preschool; Cysts; Fluorescein Angiography; Fovea Centralis; Humans; Male; Retinal Diseases; Subretinal Fluid; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity | 2021 |
Simultaneous determination of dorzolamide and timolol by first-order derivative UV spectroscopy in simulated biological fluid for in vitro drug release testing.
Topics: Antihypertensive Agents; Drug Combinations; Drug Liberation; Ophthalmic Solutions; Reproducibility of Results; Sulfonamides; Thiophenes; Timolol | 2021 |
Optical Coherence Tomography Angiography Vessel Density Changes in Normal-tension Glaucoma Treated With Carteolol, Brimonidine, or Dorzolamide.
Topics: Angiography; Brimonidine Tartrate; Carteolol; Female; Fluorescein Angiography; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Nerve Fibers; Retinal Ganglion Cells; Retinal Vessels; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Fields | 2021 |
Spectrally Resolved Estimation of Water Entropy in the Active Site of Human Carbonic Anhydrase II.
Topics: Carbonic Anhydrase II; Catalytic Domain; Entropy; Humans; Hydrogen Bonding; Lipid Bilayers; Protein Binding; Sulfonamides; Thiophenes; Water | 2021 |
Regression of taxane-related cystoid macular edema after topical dorzolamide treatment: two case reports.
Topics: Aged; Female; Humans; Macular Edema; Male; Quality of Life; Sulfonamides; Taxoids; Thiophenes; Tomography, Optical Coherence | 2021 |
RECURRENCE RATE OF CYSTOID MACULAR EDEMA WITH TOPICAL DORZOLAMIDE TREATMENT AND ITS RISK FACTORS IN RETINITIS PIGMENTOSA.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Female; Follow-Up Studies; Humans; Incidence; Japan; Macula Lutea; Macular Edema; Male; Middle Aged; Prospective Studies; Recurrence; Retinitis Pigmentosa; Risk Assessment; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Tomography, Optical Coherence; Visual Acuity | 2022 |
Cases reports: Unintended anti-doping rule violation after dorzolamide use several months prior to a doping control.
Topics: Administration, Ophthalmic; Adult; Carbonic Anhydrase Inhibitors; Doping in Sports; Female; Half-Life; Humans; Sulfonamides; Thiophenes; Time Factors | 2021 |
Impact of dorzolamide, benzalkonium-preserved dorzolamide and benzalkonium-preserved brinzolamide on selected biomarkers of oxidative stress in the tear film.
Topics: Benzalkonium Compounds; Biomarkers; Carbonic Anhydrase Inhibitors; Humans; Ophthalmic Solutions; Oxidative Stress; Sulfonamides; Thiazines; Thiophenes | 2021 |
Clinical and Genetic Study of X-Linked Juvenile Retinoschisis in the Czech Population.
Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Czech Republic; Eye Proteins; Gene Frequency; Humans; Infant; Mutation; Pedigree; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence | 2021 |
Case Series: Small Full-thickness Macular Hole Treated with Topical Dorzolamide and Bevacizumab Intravitreal Injections.
Topics: Aged; Angiogenesis Inhibitors; Bevacizumab; Female; Humans; Intravitreal Injections; Retinal Perforations; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome | 2021 |
Adverse analytical finding due to red blood cells transfusion: A rare case involving the diuretic dorzolamide.
Topics: Chromatography, Liquid; Diuretics; Erythrocytes; Humans; Male; Sulfonamides; Tandem Mass Spectrometry; Thiophenes | 2022 |
Reversible Corneal Decompensation Caused by a Topical Dorzolamide/Timolol Fixed Combination After Descemet Stripping Automated Endothelial Keratoplasty.
Topics: Aged; Corneal Diseases; Corneal Edema; Descemet Stripping Endothelial Keratoplasty; Endothelium, Corneal; Female; Humans; Sulfonamides; Thiophenes; Timolol | 2022 |