Page last updated: 2024-08-18

thiophenes and dorzolamide

thiophenes has been researched along with dorzolamide in 644 studies

Research

Studies (644)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.16)18.7374
1990's138 (21.43)18.2507
2000's296 (45.96)29.6817
2010's174 (27.02)24.3611
2020's35 (5.43)2.80

Authors

AuthorsStudies
Constanzer, ML; Matuszewski, BK1
Carlson, LE; Ehinger, B; Eriksson, LO; Finnström, K; Holmin, C; Lippa, EA; Nilsson, SE; Nyman, K; Raitta, C; Ringvold, A1
Brunner-Ferber, E; Feicht, B; Hofmann, HM; Lippa, E; von Denffer, H1
Podos, SM; Serle, JB; Sugrue, MF; Wang, RF2
Podos, SM; Serle, JB1
Deasy, DA; Epstein, DL; Higginbotham, EJ; Holder, DJ; Kass, MA; Lippa, EA; Schuman, JS; Shaw, B; Skuta, GL; Weinreb, RN1
Baldwin, JJ; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF2
Miyamoto, S; Nakagami, T; Sawa, M; Yamazaki, Y1
Strahlman, E; Tipping, R; Vogel, R2
Palmberg, P1
Biollaz, J; Brunner-Ferber, F; Buclin, T; Gervasoni, JP; Jaquet, F; Magnin, JL; Munafo, A1
Serle, JB1
Miyamoto, S; Sawa, M; Yamazaki, Y2
Constanzer, ML; Kiganda, M; Matuszewski, BK1
Au, T; Constanzer, ML; Haddix, H; Matuszewski, BK; Woolf, EJ1
Cyrlin, M; Deasy, D; Esposito, D; Fazio, R; Lippa, EA; Panebianco, D; Shields, MB; Wilkerson, M; Yablonski, M1
Bosc, JM; Bron, AM; George, JL; Greve, EL; Gunning, FP; Lesure, P; Royer, JG; Sirbat, D1
Barber, BL; Santanello, NC1
Fineman, MS; Katz, LJ; Wilson, RP1
Ballantyne, C; Gray, TB; Simpson, AJ1
Hussar, DA1
Bayer, A; Erb, C; Ferrari, F; Maren, TH1
Clineschmidt, CM; Strahlman, ER; Tipping, R; Vogel, R1
Prell, R1
Barrish, A; Bruhin, PJ; Lin, JH; Wong, BK1
Geyer, O; Michaeli-Cohen, A1
Donohue, EK; Wilensky, JT1
Pfeiffer, N1
Sugrue, MF2
Kato, K; Sugai, N; Suzuki, K; Terashima, H1
Drake, MV1
Brubaker, RF; Larsson, LI; Maus, TL; McLaren, JW1
Arend, O; Arend, S; Harris, A; Martin, B1
Brinchman-Hansen, O; Heijl, A; Puustjärvi, T; Strahlman, E; Sverrisson, T; Tipping, R1
Conroy, CW; Levy, NS; Maren, TH; Wynns, GC1
Debon, C; Hariton, C; Percicot, CL; Schnell, CR1
Armegioiu, M; Gafencu, O; Ionita, M1
Balfour, JA; Wilde, MI1
Chavez, CM; Constanzer, ML; Matuszewski, BK1
Adelman, AE; Fiscella, RG; Fishman, GA; Grover, S1
Brooks, AM; Gillies, WE2
DuPont, J; Grunwald, JE; Mathur, S1
Allingham, RR; Choudhri, SA; Cox, T; Damji, KF; Herndon, LW; Shields, MB1
Bucci, MG; Centofanti, M; Manni, GL; Napoli, D1
Kohlhaas, M; Mammen, A; Richard, G1
Denk, PO; Knorr, M; Kriegerowski, M; Thiel, HJ1
Baltatzis, S; Kokolakis, SN; Ladas, ID; Panagiotidis, D; Theodossiadis, GP; Zafirakis, P1
Rocchi, A; Tingey, D1
Alm, A; Brubaker, R; Larsson, LI; Maus, T; Wayman, L1
Spencer, AF; Vernon, SA; Zambarakji, HJ1
Dick, B; Pillunat, LE; Schmidt, KG; von Rückmann, A1
Bourne, WM; Egan, CA; Hodge, DO; McLaren, JW1
Hong, PH; Krupin, T; Rosenberg, LF; Ruderman, JM; Tang, LQ1
Alm, A; Larsson, LI1
Izdebska, J1
Garrison, PM; Stewart, WC1
Ciocci, G; Landolfi, C; Marchetti, M; Milanese, C1
Elliott, WR; Harris, A; Harrison, J; Kavanagh, J; Sponsel, WE; Trigo, Y1
Barisani, T; Baumgartner, I; Biowski, R; Hommer, A; Kaminski, S; Koyuncu, D1
Bucci, MG; Centofanti, M; Manni, GL; Napoli, D; Parisi, V1
Longo, A; Ott, JP; Reibaldi, A; Russo, V; Uva, MG1
Rehůrek, J; Vancurová, J1
Lee, MS; Pasha, M; Weitzman, M1
Le Guilloux, JC1
Burnstein, Y; Higginbotham, EJ; Shelton, K1
Adamsons, I; Snyder, E; Strohmaier, K1
Brubaker, RF; Maus, TL; Vanlandingham, BD1
Adamsons, I; Clineschmidt, C; Laibovitz, R; Polis, A; Shedden, A; Taylor, J1
Adamsons, I; Ghosh, K; Horwitz, B; Khosrof, SA; Lass, JH; Laurence, JK1
Harris, A; Ugi, IA; Wegner, A1
Brubaker, RF; Vanlandigham, BD1
Gould, LF1
Gramer, E1
Silver, LH2
De Hoste, F; Detry-Morel, M1
Hustead, JD1
Brown, SV; Dennis, RF; Epstein, R; Konowal-Allen, A1
Durand-Cavagna, G; Plazonnet, B; Ponticello, GS; Sugrue, MF1
Adamsons, I; DuBiner, H; Snyder, E; Strohmaier, K2
Adamsons, IA; Boyle, JE; Ghosh, K; Gieser, DK2
Adamsons, IA; Clineschmidt, CM; Snyder, E; Williams, RD2
Briganti, F; Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT2
Lukaris, A; Roberts-Harry, TJ; Rogers, ZA; Sells, M; Zohdy, GA1
Brubaker, R; Dinslage, S; McLaren, J1
Aalto-Korte, K1
Brubaker, RF; Larsson, LI; Maus, TL; Wayman, LL1
Gerdtham, U; Jönsson, L; Kobelt, G; Krieglstein, GK1
Hoyng, PF; Rasker, MT1
Mermoud, A1
Adamsons, IA; Boyle, JE; Ostrov, CS; Polis, A1
Adamsons, IA; Hutzelmann, JE; Michael, AJ; Polis, AB1
Adamsons, I; Hutzelmann, J; Owens, S; Shedden, A; Vargas, E1
Pillunat, LE; Schmidt, KG; von Rückmann, A1
D'Andrea, A; D'Andrea, D; Ferreri, G1
Jörg, KM; Lachmann, C; Trinkmann, R1
Challa, P; Fanous, MM; Maren, TH1
Gebhardt, DO1
Güler, C; Kimal Arici, M; Topalkara, A1
Krupin, T; Talluto, DM; Wyse, TB1
Brucculeri, M; Hammel, T; Harris, A; Malinovsky, V; Martin, B1
Brown, SV; Cooke, DL; Dennis, RF; Epstein, RJ; Fraunfelder, FT; Konowal, A; Maguire, LJ; Morrison, JC; Verdier, DV1
Bauer, NJ; Hendrikse, F; March, WF; Motamedi, M; Webers, CA; Wicksted, JP1
Capeans, C; Gonzalez, F; Martinez, A; Perez, R; Sanchez-Salorio, M1
thoe Schwartzenberg, GW; Trope, GE1
Bron, A; Chapard, J; Creuzot-Garcher, C; D'Athis, P; Guerzider, V1
Banditt, P; Behrens-Baumann, W; Meyer, FP; Motschmann, M; Schmitz, K1
Bourne, WM1
Odberg, T1
Böhm, AG; Klemm, M; Köller, AU; Pillunat, LE; Richard, G; Schmidt, KG1
Arend, O; Chung, HS; Garrett, M; Harris, A; Kagemann, L; Martin, B1
Carlsen, J; Crandall, A; Durcan, J; Swartz, M; Zabriskie, N1
Chang, MR; Cheng, Q; Hartenbaum, D; Le, HH; Lee, DA1
Hartenbaum, D; Maloney, S; Orillac, R; Sharpe, E; Vacarelli, L; Wilson, H1
Carstens, E; Carstens, MI; Dessirier, JM; O'Mahony, M; Simons, CT1
Nass, JU; Nuskovski, M; Thieme, H; Wiederholt, M1
Bang, K; Dollerup, J; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Scherfig, E; Stefánsson, E1
Gormley, GJ; Hartenbaum, D; Liss, C; Maloney, S; Vaccarelli, L; Wilson, H1
Brubaker, RF; Ingram, CJ1
Adamsons, I; Gross, R; Pearson, J; Rusk, C; Sverrisson, T1
Hudgins, AC; Pruitt, CA; Sine, C; Stewart, WC1
Buckley, EG; Freedman, SF; Portellos, M1
Herbort, CP; Mermoud, A; Schnyder, CC; Tran, VT1
Findl, O; Georgopoulos, M; Menapace, R; Rainer, G; Schmetterer, K; Vass, C1
Adamsons, I1
Chakraborty, P; Tinu, AT; Villada, JR1
Karger, BL; Kautz, RA; Tim, RC1
Becker, R; Pillunat, LE; Schmidt, KG; von Rückmann, A1
Apatachioae, I; Chiselita, D; Poiata, I1
Damji, KF; Daneshvar, H; Gilberg, SM; Goela, A1
Emmerich, KH1
Barnes, GE; Chandler, ML; Dean, T; Li, B1
Sall, K1
Haddad, P1
Amyot, M; Boisjoly, HM; Charest, M; Giasson, CJ; Lesk, MR; Nguyen, TQ1
Brubaker, RF; Ingram, CJ; Nau, CB; Schoff, EO1
Arend, O; Cantor, L; Chung, HS; Harris, A; Kagemann, L; Martin, B1
Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS1
Bufidis, T; Hudgins, AG; Konstas, AG; Maltezos, A; Stewart, WC1
Nicolela, MT; Oga, E; Susanna, R1
Samuelson, TW; Simmons, ST1
Castiglioni, S; Chrambach, A; Eberini, I; Gianazza, E; Rondanini, A; Sirtori, CR; Vecchio, G1
O'Donoghue, EP1
Bucci, MG; Centofanti, M; Cocco, F; Gregori, D; Lorenzano, D; Manni, G1
Chopra, H; Day, DG; Holmes, KT; Kolker, AE; Konstas, AG; Lee, WH; Rieser, JC; Sharpe, ED; Stewart, WC1
Day, DG; Harbin, TS; Holmes, KT; Pastor, SA; Sharpe, ED; Stewart, JA; Stewart, WC1
Autelitano, A; Bottoli, A; Invernizzi, T; Orzalesi, N; Rossetti, L1
Brenner, S; Orion, E; Spivak, D1
Kobayashi, M; Naito, K1
Bang, K; Dollerup, J; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Stefánsson, E; Wiencke, AK1
Khan, MA; Sanders, R; Taguri, AH1
Bjarnadóttir, G; Gudmundsdóttir, E; Gudmundsdóttir, G; Loftsson, T; Masson, M; Sigurjónsdóttir, JF; Stefánsson, E1
Bergua, A; Horn, FK; Jünemann, A; Korth, M; Velten, IM1
Barnebey, H; Kwok, SY1
Findl, O; Georgopoulos, M; Heinze, G; Kiss, B; Menapace, R; Rainer, G1
Choudhri, S; Shields, MB; Wand, M1
Pek, H; Wilhelm, H1
Gagliuso, DJ; Podos, SM; Serle, JB; Wang, RF1
Gomez, ML; Honrubia, FM; Larrosa, JM; Pablo, L; Polo, V1
McClellan, K; Ormrod, D1
Herkel, U; Pfeiffer, N2
Rehůrek, J; Spicarová, R; Vancurová, J1
Aurilia, P; Boles Carenini, B; Durante, A; Guarnaccia, G1
Brogliatti, B; Cipullo, D; Rolle, T; Vizzeri, GM1
Danese, M; Martin, XD1
Hoshaw-Woodard, S; Robbin, TE; Schmall, ML; Wilkie, DA; Willis, AM1
Casini, A; Ilies, MA; Menabuoni, L; Mincione, F; Scozzafava, A; Supuran, CT1
Simmons, ST1
Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G1
Anielska, E; Czechowicz-Janicka, K; Dyczkowska, A; Orlewska, E; Tobota, Z1
Gelatt, KN; MacKay, EO1
Cawrse, MA; Hendrix, DV; Ward, DA1
Bernd, AS; Böhm, AG; Pillunat, LE; Richard, G; Schmidt, KG1
Higaki, Y; Kawashima, M; Shimada, M1
Asensio Sánchez, VM1
Friren, B; Michaud, JE1
Krueger, RR; Nagy, ZZ; Süveges, I; Szabó, A1
Potocký, M1
Andreanos, D; Dimitrakoulias, N; Kandarakis, A; Mylopoulos, N; Petounis, A1
Chang, B; James, T; Mitra, M1
Cole, C; Garzozi, H; Harris, A; Jonescu-Cuypers, CP; Kagemann, L; Martin, B; Nowacki, EA1
Jurkowska-Dudzińska, J; Kawa, P; Zagórski, Z; Zarnowski, T1
Berdondini, RM; Mancuso, G1
Dick, HB; Krummenauer, F; Schwenn, O; Xia, N1
Flammer, J; Gherghel, D; Gugleta, K; Orgül, S1
Holdiness, MR1
Gressnerová, S; Oláh, Z; Veselá, A; Veselovský, J4
Chang, HW; Tsai, JC1
Bebawy, LI1
Beehne, K; Delaney, YM; Gee, B; Mossa, F; Powell, S; Salmon, JF1
Banditt, P; Martens-Lobenhoffer, J1
Erk, N3
Bucolo, C; Maltese, A1
Diehl, KA; Robbin, TE; Willis, AM1
Bergstrand, IC; Harris, A; Heijl, A1
Balado Vázquez, P; Conejero Arroyo, J; Domingo Gordo, B; Rodríguez Ausín, P; Urcelay Segura, JL1
Azuara-Blanco, A; Bain, M; Bateman, DN; Clark, R; Forrest, J1
Cabarga Del Nozal, C; García Campos, JM; Luque Aranda, R; Silva Silva, G; Vázquez Salvi, A1
El Sherbini, M; Flammer, J; Gekkieva, M; Haefliger, IO1
Easthope, SE; Perry, CM1
Martone, JF; Mead, A; O'Connor, DJ1
Avila, MY; Civan, MM; Seidler, RW; Stone, RA1
Dios Castro, E; Maquet Dusart, JA1
Halper, LK; Hartenbaum, D; Johnson-Pratt, L; Polis, A; Stewart, WC1
Larsson, LI; Mishima, HK; Orzalesi, N; Rossetti, L; Takamatsu, M1
Bron, AM; Emmerich, KH1
Adamsons, I; Cunha-Vaz, J; Miglior, S; Pfeiffer, N; Torri, V; Zeyen, T4
Bron, A1
Bonanno, JA; Ong, A; Srinivas, SP; Zhai, CB1
Phelan, P1
Bottoli, A; Fogagnolo, P; Fumagalli, E; Invernizzi, T; Orzalesi, N; Rossetti, I1
Bucci, MG; Centofanti, M; Gregori, D; Manni, G; Migliardj, R; Oddone, F; Scipioni, M1
Davani, S; Delbosc, B; Kantelip, JP; Royer, B1
Bernays, ME; Hampson, EC; Smith, RI1
Cantor, LB1
Ermis, SS; Inan, UU; Ozturk, F2
Honrubia, FM; Larsson, LI; Spiegel, D1
Lanzl, I; Nagel, E; Vilser, W2
Berdeaux, G; Berto, P; Gouveia Pinto, C; Le Pen, C; Rouland, JF1
Day, DG; Leech, J; Schacknow, PN; Sharpe, ED; Stewart, JA; Stewart, WC; Wand, M1
Konstas, AG; Kozobolis, VP; Leech, J; Stewart, WC; Tersis, I1
Funk, RW; Gersch, U; Reber, F1
Boyle, DR; Cassel, DA; DeLucca, PT; Fletcher, CA; Greff, LJ; Johnson-Pratt, LR; Kolodny, AH; Polis, AB; Sall, KN; Skobieranda, F1
Recker, K1
Amaral, M; Arieta, C; Crosta, C; de Carvalho Moreira Filho, D; José, N; Matuda, E1
Leech, JN; Stewart, JA; Stewart, WC1
Bottoli, A; Fogagnolo, P; Fumagalli, E; Orzalesi, N; Rossetti, L1
Brignoli, R; Mermoud, A; Ravinet, E1
Hommer, A; Kapik, B; Shams, N1
Pajic, B1
Drexler, W; Findl, O; Heinzl, H; Kiss, B; Petternel, V; Wirtitsch, MG1
Dziezyc, J; Rainbow, ME1
Ciulla, TA; Garzozi, HJ; Harris, A; Kagemann, L; Piper, HC; Pratt, LM; Rechtman, E1
Cantor, LB; Hoop, J; Katz, LJ; Lin, JC; Samuel, F; Spaeth, GL1
Bacharach, J; Delgado, MF; Iwach, AG1
Fong, JC; Hong, SJ; Wang, HZ; Wu, KY1
Flammer, J; Gugleta, K; Orgül, S1
Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzalkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska, A1
Houliara, D; Konstas, AG; Papapanos, P; Stewart, WC; Tersis, I1
Ahmed, MA; Geh, V; Morris, S; Nischal, KK; Sahi, S1
Cimino, L; Gandolfi, SA; Mora, P; Orzalesi, N; Rossetti, L; Tardini, M1
Mozaffari, E; Reardon, G; Schwartz, GF1
Nesher, R; Ticho, U1
Arend, O; Harris, A; Remky, A; Wolter, P1
Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G; Sacu, S; Schmid, K1
Akaishi, T; Hara, H; Kuwayama, Y; Matsugi, T; Miyawaki, N; Shimazaki, A1
Chen, YF; Hung, PT; Yang, CH1
Bauer, P; Eichler, H; Findl, O; Groke, I; Schmetterer, L; Sycha, T; Vass, C1
Casini, A; Menabuoni, L; Mincione, F; Scozzafava, A; Starnotti, M; Supuran, CT1
Assalian, A; Castilloux, AM; Houde, M; LeLorier, J; Tingey, D1
Amano, S; Inoue, K; Inoue, Y; Kato, S; Okugawa, K; Oshika, T; Tomita, G1
Pandey, RM; Ratan, SK; Sodhi, PK1
Bang, K; Eysteinsson, T; Josefsson, A; Sigurdsson, SB1
Araie, M; Azuma, I; Hamanaka, T; Kitazawa, Y; Origasa, H; Shirato, S; Tomita, G1
Bang, K; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Pedersen, DB; Stefánsson, E2
Larsson, LI; Tsukamoto, H1
Amoako-Mensah, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Georgopoulos, M; Kircher, K; Rainer, G; Schmetterer, L; Vass, C; Wally, B1
Day, DG; Holmes, KT; Jenkins, JN; Stewart, JA; Stewart, WC1
Aoyama, Y; Hada, N; Inoue, J; Kobayashi, S; Oka, M; Takeda, T; Takehana, M; Ueno, S1
Feldman, RM; Sheu, WP; Shin, DH1
Aoyama, Y; Hashimoto, M; Motoki, M1
Dutta, B; Lones, R; Mullins, RJ1
Cassel, DA; DeLucca, PT; Hustad, CM; Kolodny, AH; Skobieranda, F; Solish, AM1
Fechtner, RD; Henry, C; Hughes, B; Lee, DA; Terry, S; Whitson, JT1
Gabelt, BT; Kaufman, PL; Kiland, JA1
Camras, CB; Toris, CB; Yablonski, ME; Zhan, GL1
Strutton, DR; Walt, JG1
Arias Puente, A; Carrasco Font, C; García Sáenz, MC; Villarejo Díaz-Maroto, I1
Benz, MS; Eifrig, CW; Escalona-Benz, EM; Moore, JK; Murray, TG; Schiffman, JC; Yoder, DM1
Akman, A; Akova, YA; Cetinkaya, A; Ertan, A1
Attanasio, A; Baglio, S; Bartorelli, L; Quatrana, M1
Beischel, CJ; Day, DG; Rhodes, JS; Sharpe, ED; Stewart, JA; Stewart, WC1
Christodoulakis, E; Konstas, AG; Kozobolis, VP; Lallos, N; Stewart, JA; Stewart, WC1
Sheu, WP; Susanna, R; Sussana, R1
Brown, SV; Epstein, RJ; Konowal, A1
McKay, IC; Montgomery, DM; Morris, D; Osborne, SA1
Berke, S; Du, LT; Ehrenhaus, M; Francis, BA; Minckler, DS1
Călugăru, D; Călugăru, M2
Ardelean, C; Nenciu, A; Stefan, C1
Gupta, R; Vernon, SA1
Bishara, S; Blumenthal, EZ; Gallily, R; Goldberg, S1
Ignat, F1
Alver, A; Keha, EE; Ovali, E; Uçar, F1
Langenbucher, A; Mardin, CY; Martus, P; Schlötzer-Schrehardt, U; Viestenz, A1
Buys, YM; Faingold, D; Flanagan, J; Guan, K; Hudson, C; Rawji, M; Trope, GE1
Kazakevich, YV; LoBrutto, R; Pan, L; Thompson, R1
Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzałkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska-Zmijewska, A1
Harris, A; Janulevicienë, I; Kagemann, L; McCranor, L; Siesky, B1
Eysteinsson, T; Gudmundsdóttir, E; Loftsson, T; Sigurdsson, HH; Stefánsson, E; Thorsteinsdóttir, M1
Bayer, A; Oeverhaus, U; Skrotzki, FE; Stewart, WC; Weiler, W1
Aşagidag, A; Ermiş, SS; Inan, UU; Oztürk, F; Yaman, S1
de la Cuadra Oyanguren, J; Linares Mata, T; Pardo Sánchez, J1
Bang, K; Eysteinsson, T; Kiilgaard, JF; Koch Jensen, P; la Cour, M; Pedersen, DB; Stefánsson, E; Wiencke, AK1
Abe, H; Fukuchi, T; Hashimoto, K; Matsuda, H; Seki, M; Tanaka, T; Togano, T; Ueda, J1
Arend, O; Remky, A; Sponsel, WE; Weber, A1
Georgiadis, N; Karabatsas, CH; Konstas, AG; Kotsimpou, A; Lallos, N; Stewart, JA; Stewart, WC1
Galambos, P; Klemm, M; Matthiessen, ET; Reuss, J; Richard, G; Wagenfeld, L; Wiermann, A; Zeitz, O1
Ikeda, H; Matsuyama, S; Mishima, HK; Noma, H; Tsukamoto, H1
Klemm, M; Matthiessen, ET; Richard, G; Vilchez, SE; Zeitz, O1
Adamsons, IA; Fechtner, RD; Lines, CR; McCarroll, KA1
Quigley, HA1
Adamsons, IA; Arango, S; Assaid, CA; Getson, AJ; Mills, MD; Ott, EZ1
Aggermann, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Kolodjaschna, J; Polska, E; Rainer, G; Schmetterer, L; Vass, C; Wally, B; Weigert, G1
Conde, A; Cruces, M; de la Torre, C; Flórez, A; García-Doval, I; González, B; Rosón, E1
Ikeda, H; Mishima, HK; Mukai, S; Noma, H; Tsukamoto, H1
Doğan, S1
McEwan, GC; Patil, KA; Sarup, V; Sharma, SC; Thompson, C1
Ishikawa, S; Nakamura, Y; Sakai, H; Sawaguchi, S; Shinjyo, S1
Martínez, A; Sánchez, M3
Antohi, I; Chiseliţă, D; Danielescu, C; Medvichi, R1
Almeida, GC; Faria e Souza, SJ1
Funk, RH; Knels, L; Kniep, EM; Ozkucur, N; Reber, F; Roehlecke, C; Steinberg, A1
Apushkin, MA; Fishman, GA; Grover, S1
Hong, SJ; Wang, HZ; Wu, KY1
Conkbayir, I; Simsek, T; Yanik, B; Zilelioglu, O1
Longo, A; Reibaldi, A; Reibaldi, M; Uva, MG1
Kalavala, M; Statham, BN1
Gandolfo, E; Gandolfo, F; Musig, A; Pizzolante, T; Quaranta, L; Rovida, F; Turano, R1
Hong, S; Hong, YJ; Lee, CS; Seo, KY; Seong, GJ1
Jurisić, D; Lacmnovic-Loncar, V; Mandić, Z; Petric, I; Sesar, A; Sesar, I; Tomić, Z1
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Baker, MM; Belal, TS1
Andishmand, L; Bavarsad, N; Kouchak, M; Malekahmadi, M; Saki Malehi, A1
Biagioli, E; Galli, F; Katsanos, A; Longo, A; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN1
Chen, R; Huang, Q; Lin, X; Xiang, Z1
Lee, TE; Park, YM1
Sohrabi, MR; Valizadeh, M1
Hoffmanová, I; Sánchez, D1
Conrath, J; Donnadieu, B; Fakhoury, O; Matonti, F; Warrak, R1
Afify, AEMR; Afify, EAMR; Elsayed, I; Gad, MK; Mohamed, MI1
Menke, B; Payne, JF; Walters, A1
Hirji, N; Kalitzeos, A; Michaelides, M; Quartilho, A; Strong, SA1
Kim, DG; Kim, HW; Lee, SJ; Yoon, CK1
Abdelrehim, RT; Fouda, NH; Habib, BA; Hegazy, DA1
Arciniegas-Perasso, CA; Clemente-Tomás, R; Duch-Samper, AM; García-Ibor, F; Hervás-Hernandis, JM; Ruiz-Del Río, N1
Ghasempour, M; Khojasteh, H; Riazi-Esfahani, H; Roohipoor, R1
Biagioli, E; Galli, F; Katsanos, A; Longo, A; Oddone, F; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN1
Donaldson, D; McFadzean, WJ; Murrell, J1
Batich, C; Bechtle, A; Eiferman, R; Gibson, D; Guidi, C; Schultz, G; Stanton, D; Yang, Q1
Rathi, A; Saxena, H; Sharma, B; Takkar, B1
Kumar, V; Kumawat, D1
Hwang, CK; Kim, BJ; Kolomeyer, AM1
Berrino, E; Carta, F; Eysteinsson, T; Gudmundsdottir, H; Hardarson, AO; Selleri, S; Supuran, CT1
Hsu, J; Obeid, A; Su, D1
El Abass, SA; Elmansi, HM; Ibrahim, FA1
Manabe, Y; Mochizuki, K; Sawada, A1
Boevé, MH; de Gee, R; Djajadiningrat-Laanen, SC; Elders, DJ; Koele, LE; Slenter, IJM; Vermeer, LW1
Farrahi, F; Kouchak, M; Mahmoodzadeh, M1
Jung, JH; Kim, SI; Lee, JE; Lee, SM; Shin, J1
Figueiredo, R; Garrido, J; Morais Sarmento, T; Ramalho, A1
Kaur, G; Mittal, N1
Cardoso, VN; Castilho, RO; Cronemberger, S; Faraco, AAG; Fernandes, SOA; Ferreira, AJ; Foureaux, G; Franca, JR; Fuscaldi, LL; Nogueira, JC; Ribeiro, TG; Yoshida, MI1
Banerjee, M; Chawla, R1
Bek, T; Tilma, KK1
Fazel, F; Nikpour, H; Pourazizi, M1
Abdelmoteleb, M; Amin, MM; Khowessah, OM; Sayed, S1
Huang, S; Xing, Y; Zhang, K; Zhu, L1
Biagioli, E; Galli, F; Longo, A; Michelessi, M; Oddone, F; Quaranta, L; Riva, I; Rulli, E; Uva, MG; Weinreb, RN1
Esfandiari, H; Tanna, AP; Teramoto, K1
Glassman, AR1
Han, X; Kam, WR; Liu, Y; Sullivan, DA; Yang, S1
Fujiwara, K; Funatsu, J; Ikeda, Y; Murakami, Y; Nakatake, S; Shimokawa, S; Sonoda, KH; Yoshida, N1
Azad, S; Kumar, V; Surve, A; Thangavel, R1
Abe, F; Higuchi, T; Mitsuyama, S1
Bras, D; Grozdanic, S; Komáromy, AM; McLellan, G; Miller, P; Plummer, CE; Sapienza, JS; Teixeira, L; Webb, T1
Alshehri, S; Imam, SS; Rizwanullah, M; Shahab, MS1
Czepiel, TM; Wasserman, NT1
Holló, G; Hutnik, CML; Katsanos, A; Katz, LJ; Konstas, AG; Pfeiffer, N; Quaranta, L; Schmetterer, L; Teus, MA; Uusitalo, H1
Jaswal, S; Kumar, S; Monga, V; Rulhania, S1
Kamshilin, AA; Mamontov, OV; Osipchuk, AV; Romashko, RV; Sokolov, AY; Volynsky, MA; Zaytsev, VV1
Karkhur, S; Sharma, B; Soni, D1
Azad, SV; Gowdar Kuberappa, R; Kumar, V; Vukkadala, T1
Akaray, İ; Çınar, AC; Çınar, AK; Güçlü, H; Gürlü, V; Sakallıoğlu, AK; Şambel Aykutlu, M1
Amin, P; Jain, D; Tambe, S1
Chen, LC; Chuang, LH; Huang, SM; Lin, YH; Su, WW1
Das, CK; Päslack, C; Schäfer, LV; Schlitter, J1
Kamiya, T; Kinouchi, R; Otsubo, M; Yoshida, A1
Akiyama, M; Fujiwara, K; Funatsu, J; Ikeda, Y; Koyanagi, Y; Murakami, Y; Nakatake, S; Shimokawa, S; Sonoda, KH; Takeda, A; Yoshida, N1
Faiss, R; Krzywański, J; Pokrywka, A; Rynkowski, M; Saugy, M; Skrzypiec-Spring, M1
Borymska, W; Sedlak, L; Świerczyńska, M; Wyględowska-Promieńska, D; Zych, M1
Çakmak, K; Erbil, H; Korkmaz, Ş; Mesci, C1
Brichova, M; Dubska, Z; Dudakova, L; Dvorakova, L; Hlavata, L; Kousal, B; Langrova, H; Liskova, P; Vincent, AL; Vlaskova, H1
Berrocal, AM; El Hamichi, S; Feria Anzaldo, E; Gold, A; Latiff, A; Murray, T1
Gheddar, L; Kintz, P; Raul, JS1
Jun, JH; Kwak, J1

Reviews

54 review(s) available for thiophenes and dorzolamide

ArticleYear
A topical carbonic anhydrase inhibitor finally arrives.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:8

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes

1995
Pharmacological advances in the treatment of glaucoma.
    Drugs & aging, 1994, Volume: 5, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Ethacrynic Acid; Glaucoma; Humans; Latanoprost; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes

1994
[Topical carbonic anhydrase inhibitors in the treatment of glaucoma].
    Journal francais d'ophtalmologie, 1996, Volume: 19, Issue:5

    Topics: Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ophthalmic Solutions; Sulfonamides; Thiophenes

1996
[Topical carbonic anhydrase inhibitors for glaucoma].
    Harefuah, 1996, May-15, Volume: 130, Issue:10

    Topics: Acetazolamide; Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Methazolamide; Sulfonamides; Thiophenes

1996
Trusopt, a topical carbonic anhydrase inhibitor.
    Journal of glaucoma, 1996, Volume: 5, Issue:1

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes

1996
[Local carbonic anhydrase inhibitor dorzolamide: development and properties].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1996, Volume: 93, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Structure-Activity Relationship; Sulfonamides; Thiophenes

1996
The preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1996,Fall, Volume: 12, Issue:3

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dogs; Drug Combinations; Drug Evaluation, Preclinical; Glaucoma; Intraocular Pressure; Macaca; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Timolol

1996
New medical therapies for glaucoma.
    International ophthalmology clinics, 1996,Spring, Volume: 36, Issue:2

    Topics: Adrenergic alpha-Agonists; Carbonic Anhydrase Inhibitors; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome

1996
Dorzolamide. A review of its pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension.
    Drugs & aging, 1997, Volume: 10, Issue:5

    Topics: Absorption; Aging; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Controlled Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quality of Life; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Tissue Distribution

1997
[Trusopt--a new form of drug for treating glaucoma].
    Klinika oczna, 1997, Volume: 99, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Therapy, Combination; Glaucoma; Intraocular Pressure; Pilocarpine; Sulfonamides; Thiophenes

1997
Beta-blocker-induced complications and the patient with glaucoma. Newer treatments to help reduce systemic adverse events.
    Archives of internal medicine, 1998, Feb-09, Volume: 158, Issue:3

    Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Cardiovascular System; Central Nervous System; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Neurosecretory Systems; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Respiratory System; Sulfonamides; Thiophenes

1998
Dorzolamide, a 40-year wait. From an oral to a topical carbonic anhydrase inhibitor for the treatment of glaucoma.
    Pharmaceutical biotechnology, 1998, Volume: 11

    Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sulfonamides; Thiophenes

1998
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
    Nederlands tijdschrift voor geneeskunde, 1998, Sep-26, Volume: 142, Issue:39

    Topics: Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Combination; Female; Glaucoma; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes

1998
Topical carbonic anhydrase inhibitors.
    Current opinion in ophthalmology, 1997, Volume: 8, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Treatment Outcome

1997
Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors.
    Progress in retinal and eye research, 2000, Volume: 19, Issue:1

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Forecasting; Glaucoma; Humans; In Vitro Techniques; Sulfonamides; Thiazines; Thiophenes

2000
[Pharmacological profiles of the potent carbonic anhydrase inhibitor dorzolamide hydrochloride, a topical antiglaucoma agent].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2000, Volume: 115, Issue:6

    Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes

2000
Topical dorzolamide 2%/timolol 0.5%: a review of its use in the treatment of open-angle glaucoma.
    Drugs & aging, 2000, Volume: 17, Issue:6

    Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Timolol; Vision, Ocular

2000
Update on topical carbonic anhydrase inhibitors.
    Current opinion in ophthalmology, 2001, Volume: 12, Issue:2

    Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Eye; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes

2001
Dorzolamide-induced immune thrombocytopenia: a case report and literature review.
    Journal of glaucoma, 2001, Volume: 10, Issue:2

    Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Male; Platelet Count; Sulfonamides; Thiophenes; Thrombocytopenia

2001
Contact dermatitis to topical drugs for glaucoma.
    American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 2001, Volume: 12, Issue:4

    Topics: Dermatitis, Allergic Contact; Epinephrine; Glaucoma; Humans; Ophthalmic Solutions; Pilocarpine; Sulfonamides; Thiophenes; Timolol

2001
Clinical pharmacokinetics of dorzolamide.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:3

    Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ciliary Body; Cornea; Erythrocytes; Glaucoma; Humans; Intraocular Pressure; Isoenzymes; Ophthalmic Solutions; Sulfonamides; Thiophenes

2002
Advances in topical glaucoma therapy.
    Veterinary ophthalmology, 2002, Volume: 5, Issue:1

    Topics: Administration, Topical; Animals; Cat Diseases; Cats; Clonidine; Dog Diseases; Dogs; Glaucoma; Humans; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes

2002
Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension.
    Drugs & aging, 2002, Volume: 19, Issue:3

    Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctival Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2002
The effect of latanoprost on circadian intraocular pressure.
    Survey of ophthalmology, 2002, Volume: 47 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol

2002
Latanoprost versus combined timolol and dorzolamide.
    Survey of ophthalmology, 2002, Volume: 47 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2002
[Comparison of latanoprost monotherapy with timolol-dorzolamide combination in patients with open-angle glaucoma or ocular hypertension].
    Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:6

    Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2002
Reappraising first-line treatment in glaucoma management.
    Hospital medicine (London, England : 1998), 2002, Volume: 63, Issue:9

    Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Dinoprost; Drug Therapy, Combination; Glaucoma; Humans; Latanoprost; Lipids; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Travoprost

2002
An update on bimatoprost in glaucoma therapy.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amides; Antihypertensive Agents; Benzimidazoles; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Omeprazole; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes

2002
Four years later: a clinical update on latanoprost.
    European journal of ophthalmology, 2003, Volume: 13, Issue:2

    Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol

2003
Interventions for normal tension glaucoma.
    The Cochrane database of systematic reviews, 2003, Issue:4

    Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Vincamine

2003
[Timolol topical ophthalmic combination].
    Oftalmologia (Bucharest, Romania : 1990), 2004, Volume: 48, Issue:1

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2004
Intraocular pressure-lowering effect of adding dorzolamide or latanoprost to timolol: a meta-analysis of randomized clinical trials.
    Ophthalmology, 2007, Volume: 114, Issue:1

    Topics: Antihypertensive Agents; Databases, Factual; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol

2007
X-linked retinoschisis: an update.
    Journal of medical genetics, 2007, Volume: 44, Issue:4

    Topics: Adult; Age of Onset; Animals; Biopolymers; Cell Adhesion; Child; Child, Preschool; Chromosomes, Human, X; Diagnosis, Differential; Diagnostic Techniques, Ophthalmological; Disease Models, Animal; Disease Progression; Eye Proteins; Female; Genes, X-Linked; Genetic Carrier Screening; Genetic Counseling; Genetic Therapy; Humans; Infant; Macular Degeneration; Male; Mice; Phenotype; Prevalence; Protein Structure, Tertiary; Retinoschisis; Sulfonamides; Thiophenes

2007
Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension.
    Current medical research and opinion, 2007, Volume: 23, Issue:12

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome

2007
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.
    Ophthalmology, 2008, Volume: 115, Issue:7

    Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome

2008
The efficacy and harm of prostaglandin analogues for IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: a systematic review.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Female; Glaucoma; Humans; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Treatment Outcome

2008
[Fixed combinations of glaucoma medications].
    Oftalmologia (Bucharest, Romania : 1990), 2008, Volume: 52, Issue:3

    Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome

2008
Efficacy and tolerability of latanoprost compared to dorzolamide combined with timolol in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized, controlled trials.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:1

    Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol

2009
[Neuroprotection in glaucoma].
    Annales Academiae Medicae Stetinensis, 2007, Volume: 53 Suppl 1

    Topics: Betaxolol; Brimonidine Tartrate; Disease Progression; Glaucoma; Guanidines; Humans; Memantine; Neuroprotective Agents; Quinoxalines; Sulfonamides; Thiophenes

2007
Meta-analysis of medical intervention for normal tension glaucoma.
    Ophthalmology, 2009, Volume: 116, Issue:7

    Topics: Aged; Amides; Antihypertensive Agents; Betaxolol; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Travoprost

2009
Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost.
    Ophthalmic research, 2009, Volume: 42, Issue:2

    Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Databases, Factual; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Optic Nerve Diseases; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol

2009
Topical carbonic anhydrase inhibitors and visual function in glaucoma and ocular hypertension.
    Current medical research and opinion, 2010, Volume: 26, Issue:6

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ocular Hypertension; Sulfonamides; Thiazines; Thiophenes; Visual Fields

2010
Topical drug delivery to the eye: dorzolamide.
    Acta ophthalmologica, 2012, Volume: 90, Issue:7

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Aqueous Humor; Biological Availability; Carbonic Anhydrase Inhibitors; Drug Delivery Systems; Glaucoma; Humans; Ophthalmic Solutions; Sulfonamides; Thiophenes

2012
Meta-analysis of α2-adrenergic agonists versus carbonic anhydrase inhibitors as adjunctive therapy.
    Current medical research and opinion, 2012, Volume: 28, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Carbonic Anhydrase Inhibitors; Databases, Factual; Female; Humans; Intraocular Pressure; Male; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes

2012
[Mode of action, clinical profile and relevance of carbonic anhydrase inhibitors in glaucoma therapy].
    Klinische Monatsblatter fur Augenheilkunde, 2013, Volume: 230, Issue:2

    Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Ciliary Body; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes

2013
Oxidative stress and potential applications of free radical scavengers in glaucoma.
    Redox report : communications in free radical research, 2013, Volume: 18, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; DNA; Free Radical Scavengers; Ginkgo biloba; Glaucoma; Humans; Lipid Peroxidation; Oxidative Stress; Protein Carbonylation; Resveratrol; Stilbenes; Sulfonamides; Thiophenes

2013
Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Antihypertensive Agents; Drug Tolerance; Female; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol

2013
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.
    Expert opinion on drug metabolism & toxicology, 2016, Volume: 12, Issue:4

    Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal; Anticonvulsants; Antineoplastic Agents; Benzodiazepines; Carbonic Anhydrase Inhibitors; Celecoxib; Clinical Trials as Topic; Contraindications; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fructose; Humans; Isoxazoles; Methazolamide; Phenobarbital; Sulfanilamide; Sulfanilamides; Sulfonamides; Sulfonic Acids; Thiazines; Thiophenes; Topiramate; Zonisamide

2016
Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye.
    International journal of pharmaceutics, 2017, Oct-15, Volume: 531, Issue:2

    Topics: Administration, Ophthalmic; Administration, Topical; Animals; Cyclodextrins; Dexamethasone; Drug Delivery Systems; Excipients; Humans; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes

2017
Efficacy of carbonic anhydrase inhibitors in management of cystoid macular edema in retinitis pigmentosa: A meta-analysis.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Female; Humans; Macular Edema; Male; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Treatment Outcome; Visual Acuity

2017
Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature.
    Journal of medical case reports, 2018, Nov-16, Volume: 12, Issue:1

    Topics: Adenine; Administration, Topical; Aged; Anterior Chamber; Antihypertensive Agents; Antineoplastic Agents; Brimonidine Tartrate; Cataract Extraction; Humans; Intraocular Pressure; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Phacoemulsification; Piperidines; Prednisolone; Pyrazoles; Pyrimidines; Sulfonamides; Syndrome; Thiophenes; Timolol; Treatment Outcome; Visual Acuity

2018
The efficacy of the fixed combination of latanoprost and timolol versus other fixed combinations for primary open-angle glaucoma and ocular hypertension: A systematic review and meta-analysis.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome

2020
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future.
    Advances in therapy, 2021, Volume: 38, Issue:1

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2021
Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetazolamide; Animals; Antineoplastic Agents; Antioxidants; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Indoles; Isatin; Molecular Docking Simulation; Organoselenium Compounds; Oxadiazoles; Protein Binding; Protein Isoforms; Pyrimidines; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes; Urea

2021

Trials

237 trial(s) available for thiophenes and dorzolamide

ArticleYear
Dose response and duration of action of dorzolamide, a topical carbonic anhydrase inhibitor.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:4

    Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes

1992
[MK-507 (L-671 152): local tolerance and effectiveness of a new local carbonic anhydrase inhibitor in healthy probands].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:5

    Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cellulose; Double-Blind Method; Humans; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes

1991
MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors.
    Ophthalmology, 1991, Volume: 98, Issue:3

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes

1991
A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International Dorzolamide Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

1995
Whole-blood pharmacokinetics and metabolic effects of the topical carbonic anhydrase inhibitor dorzolamide.
    European journal of clinical pharmacology, 1995, Volume: 47, Issue:5

    Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Half-Life; Humans; Male; Prospective Studies; Sulfonamides; Thiophenes

1995
Four-week safety and efficacy study of dorzolamide, a novel, active topical carbonic anhydrase inhibitor.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:10

    Topics: Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Count; Cornea; Double-Blind Method; Drug Tolerance; Endothelium, Corneal; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes

1993
Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1993, Volume: 231, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Delivery Systems; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Polysaccharides, Bacterial; Sulfonamides; Thiophenes

1993
Relating spontaneous adverse experience reports to scores on a questionnaire querying tolerability.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:11

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol

1995
A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group.
    American journal of ophthalmology, 1996, Volume: 122, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol

1996
A controlled clinical trial of dorzolamide: a single-centre subset of a multicentre study.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

1996
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
    Ophthalmology, 1996, Volume: 103, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol

1996
Comparison of dorzolamide and acetazolamide as suppressors of aqueous humor flow in humans.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:1

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Fluorescein; Fluoresceins; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes

1997
Effects of topical dorzolamide on retinal and retrobulbar hemodynamics.
    Acta ophthalmologica Scandinavica, 1996, Volume: 74, Issue:6

    Topics: Administration, Topical; Antihypertensive Agents; Blood Flow Velocity; Double-Blind Method; Fluorescein Angiography; Fundus Oculi; Humans; Image Processing, Computer-Assisted; Intraocular Pressure; Lasers; Ophthalmic Solutions; Ophthalmoscopes; Orbit; Reference Values; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color

1996
A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension.
    Ophthalmology, 1997, Volume: 104, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

1997
Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosa.
    Retina (Philadelphia, Pa.), 1997, Volume: 17, Issue:3

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Visual Acuity

1997
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

1996
Effects of dorzolamide hydrochloride 2% on the retinal circulation.
    Acta ophthalmologica Scandinavica, 1997, Volume: 75, Issue:3

    Topics: Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fundus Oculi; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes

1997
Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:9

    Topics: Aged; Carbonic Anhydrase Inhibitors; Cornea; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular

1997
Comparative effects of intraocular pressure between systemic and topical carbonic anhydrase inhibitors: a clinical masked, cross-over study.
    Pharmacological research, 1997, Volume: 35, Issue:5

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Aging; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Eye Color; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes

1997
[Change in corneal sensitivity after topical dorzolamide administration. A comparative study].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1997, Volume: 94, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Antihypertensive Agents; Cornea; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Pain Threshold; Procaine; Sulfonamides; Thiophenes

1997
Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:10

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Safety; Sulfonamides; Thiophenes; Treatment Outcome

1997
Economic evaluation of dorzolamide vs. pilocarpine for primary open-angle glaucoma.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1997, Volume: 32, Issue:6

    Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Costs and Cost Analysis; Glaucoma, Open-Angle; Humans; Models, Economic; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Sulfonamides; Thiophenes

1997
Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

1997
Effect of dorzolamide on corneal endothelial function in normal human eyes.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:1

    Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Fluorescein; Fluorophotometry; Humans; Hypoxia; Intraocular Pressure; Microscopy; Middle Aged; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes

1998
Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation.
    Ophthalmology, 1998, Volume: 105, Issue:1

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular

1998
Aqueous humor flow in human eyes treated with dorzolamide and different doses of acetazolamide.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:1

    Topics: Acetazolamide; Administration, Oral; Adult; Aqueous Humor; Bicarbonates; Carbonic Anhydrase Inhibitors; Contrast Media; Double-Blind Method; Drug Therapy, Combination; Eye; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiophenes

1998
Dorzolamide hydrochloride and visual function in normal eyes.
    American journal of ophthalmology, 1997, Volume: 123, Issue:6

    Topics: Adult; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercapnia; Hypocapnia; Intraocular Pressure; Male; Ophthalmic Solutions; Pilot Projects; Sulfonamides; Thiophenes; Visual Field Tests; Visual Fields

1997
Hypotensive effects of dorzolamide eyewash in maximal therapy glaucoma patients: a comparative study with oral acetazolamide.
    Acta ophthalmologica Scandinavica. Supplement, 1997, Issue:224

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Treatment Outcome

1997
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
    Journal of the American Optometric Association, 1998, Volume: 69, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields

1998
The effect of dorzolamide on aqueous humor dynamics in normal human subjects during sleep.
    Ophthalmology, 1998, Volume: 105, Issue:8

    Topics: Administration, Topical; Adult; Anterior Eye Segment; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sleep; Sulfonamides; Thiophenes

1998
The efficacy and safety of dorzolamide as adjunctive therapy to timolol maleate gellan solution in patients with elevated intraocular pressure. Additivity Study Group.
    Journal of glaucoma, 1998, Volume: 7, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gels; Humans; Male; Middle Aged; Ocular Hypertension; Solutions; Sulfonamides; Thiophenes; Timolol

1998
A double-masked, randomized, 1-year study comparing the corneal effects of dorzolamide, timolol, and betaxolol. Dorzolamide Corneal Effects Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Cell Count; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

1998
Combined effect of dorzolamide and latanoprost on the rate of aqueous humor flow.
    American journal of ophthalmology, 1998, Volume: 126, Issue:2

    Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Uvea

1998
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
    American journal of ophthalmology, 1998, Volume: 126, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome

1998
Central corneal thickness.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:9

    Topics: Carbonic Anhydrase Inhibitors; Cornea; Glaucoma; Humans; Ocular Hypertension; Sulfonamides; Thiophenes

1998
A trial of dorzolamide for glaucoma.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:9

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Administration Routes; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Sulfonamides; Thiophenes; Treatment Outcome

1998
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group.
    Ophthalmology, 1998, Volume: 105, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol

1998
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group.
    Ophthalmology, 1998, Volume: 105, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol

1998
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group.
    Ophthalmology, 1998, Volume: 105, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol

1998
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery.
    Journal of the Royal College of Surgeons of Edinburgh, 1998, Volume: 43, Issue:5

    Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Care; Prospective Studies; Sulfonamides; Thiophenes

1998
Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Synergism; Female; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

1998
Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:11

    Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol

1998
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
    Journal of glaucoma, 1998, Volume: 7, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol

1998
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:6

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

1998
Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

1998
Topical carbonic anhydrase inhibition increases ocular pulse amplitude in high tension primary open angle glaucoma.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:7

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Cataract; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Placebos; Prospective Studies; Pulsatile Flow; Sulfonamides; Thiophenes

1998
Clinical use of a topical carbonic anhydrase inhibitor in patients affected by chronic simple glaucoma.
    Acta ophthalmologica Scandinavica. Supplement, 1998, Issue:227

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

1998
[Postoperative behavior of intraocular pressure after posterior Nd:YAG laser capsulotomy--critical evaluation in preventive administration of local carbonic anhydrase II inhibitor dorzolamide hydrochloride (Trusopt)].
    Klinische Monatsblatter fur Augenheilkunde, 1998, Volume: 213, Issue:6

    Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Premedication; Sulfonamides; Thiophenes; Treatment Outcome

1998
Additive effect of latanoprost and dorzolamide in patients with elevated intraocular pressure.
    International ophthalmology, 1998, Volume: 22, Issue:1

    Topics: Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Treatment Outcome

1998
Dorzolamide effect on ocular blood flow.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:6

    Topics: Aged; Carbonic Anhydrase Inhibitors; Eye; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Reference Values; Regional Blood Flow; Sulfonamides; Thiophenes; Ultrasonography

1999
Effect of topical dorzolamide on optic nerve head blood flow.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1999, Volume: 237, Issue:6

    Topics: Administration, Topical; Adult; Capillaries; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors

1999
Dorzolamide, visual function and ocular hemodynamics in normal-tension glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:3

    Topics: Blood Pressure; Carbonic Anhydrase Inhibitors; Double-Blind Method; Glaucoma; Heart Rate; Humans; Ocular Physiological Phenomena; Regional Blood Flow; Sulfonamides; Thiophenes; Visual Acuity

1999
A randomized study of dorzolamide in the prevention of elevated intraocular pressure after anterior segment laser surgery. Dorzolamide Laser Study Group.
    Journal of glaucoma, 1999, Volume: 8, Issue:4

    Topics: Anterior Eye Segment; Carbonic Anhydrase Inhibitors; Double-Blind Method; Humans; Intraocular Pressure; Laser Therapy; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Sulfonamides; Thiophenes

1999
Comparison of dorzolamide and pilocarpine as adjunctive therapy in patients with open-angle glaucoma and ocular hypertension.
    Clinical therapeutics, 1999, Volume: 21, Issue:9

    Topics: Adjuvants, Pharmaceutic; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Parasympathomimetics; Patient Dropouts; Pilocarpine; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome

1999
Effect of brinzolamide and dorzolamide on aqueous humor flow in human eyes.
    American journal of ophthalmology, 1999, Volume: 128, Issue:3

    Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Thiophenes

1999
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
    Journal of glaucoma, 1999, Volume: 8, Issue:5

    Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol

1999
Daily cost of newer glaucoma agents.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:5

    Topics: Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Gels; Glaucoma; Humans; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Solutions; Sulfonamides; Thiophenes; Timolol

1999
Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 1998, Volume: 2, Issue:1

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Cross-Over Studies; Female; Glaucoma; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes

1998
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components.
    Ophthalmology, 1999, Volume: 106, Issue:12 Suppl

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields

1999
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide.
    Ophthalmology, 1999, Volume: 106, Issue:12 Suppl

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol

1999
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide.
    Ophthalmology, 1999, Volume: 106, Issue:12 Suppl

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol

1999
Effect of dorzolamide and latanoprost on intraocular pressure after small incision cataract surgery.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:12

    Topics: Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome

1999
[Ocular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 1999, Volume: 215, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol

1999
[The ocular hypotensive effect of the combination of latanoprost with dorzolamide].
    Oftalmologia (Bucharest, Romania : 1990), 1999, Volume: 46, Issue:1

    Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes

1999
Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension.A 3-month randomised study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2000, Volume: 238, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2000
Ocular comfort of brinzolamide 1.0% ophthalmic suspension compared with dorzolamide 2.0% ophthalmic solution: results from two multicenter comfort studies. Brinzolamide Comfort Study Group.
    Survey of ophthalmology, 2000, Volume: 44 Suppl 2

    Topics: Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome

2000
The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open-angle glaucoma or ocular hypertension. Brinzolamide Primary Therapy Study Group.
    Survey of ophthalmology, 2000, Volume: 44 Suppl 2

    Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome

2000
Dorzolamide and corneal recovery from edema in patients with glaucoma or ocular hypertension.
    American journal of ophthalmology, 2000, Volume: 129, Issue:2

    Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cell Count; Contact Lenses; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Tonometry, Ocular

2000
Comparison of the efficacy of betaxolol-brinzolamide and timolol-dorzolamide as suppressors of aqueous humor flow in human subjects.
    Ophthalmology, 2000, Volume: 107, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aqueous Humor; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular

2000
A comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patients.
    Ophthalmology, 2000, Volume: 107, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color

2000
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
    Ophthalmology, 2000, Volume: 107, Issue:3

    Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy

2000
Twenty-four hour control of intraocular pressure with dorzolamide and timolol maleate in exfoliation and primary open-angle glaucoma.
    Eye (London, England), 2000, Volume: 14 ( Pt 1)

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes; Timolol

2000
Additive effect of latanoprost to the combination of timolol and dorzolamide.
    Journal of glaucoma, 2000, Volume: 9, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2000
Comparison of brimonidine with latanoprost in the adjunctive treatment of glaucoma. ALPHAGAN/XALATAN Study Group.
    Clinical therapeutics, 2000, Volume: 22, Issue:4

    Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome

2000
A comparison of latanoprost and dorzolamide in patients with glaucoma and ocular hypertension: a 3 month, randomised study. Ireland Latanoprost Study Group.
    The British journal of ophthalmology, 2000, Volume: 84, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Circadian Rhythm; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes

2000
Comparative acute effects of brimonidine 0.2% versus dorzolamide 2% combined with beta-blockers in glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2000, Volume: 238, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome

2000
Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocular pressure.
    American journal of ophthalmology, 2000, Volume: 129, Issue:6

    Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome

2000
Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:9

    Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2000
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:11

    Topics: Carbonic Anhydrase Inhibitors; Cyclodextrins; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Methazolamide; Ocular Hypertension; Ophthalmic Solutions; Pharmaceutical Vehicles; Sulfonamides; Thiophenes

2000
Patients' acceptance of a switch from dorzolamide to brinzolamide for the treatment of glaucoma in a clinical practice setting.
    Clinical therapeutics, 2000, Volume: 22, Issue:10

    Topics: Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Patient Satisfaction; Prospective Studies; Sulfonamides; Thiazines; Thiophenes

2000
Randomised fellow eye comparison of the effectiveness of dorzolamide and apraclonidine on intraocular pressure following phacoemulsification cataract surgery.
    Eye (London, England), 2000, Volume: 14 Pt 5

    Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Female; Humans; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Prospective Studies; Sulfonamides; Thiophenes

2000
A comparison of dorzolamide-timolol combination versus the concomitant drugs.
    American journal of ophthalmology, 2000, Volume: 130, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol

2000
[Effect of dorzolamide on accommodation and pupillary reaction?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2000, Volume: 97, Issue:11

    Topics: Accommodation, Ocular; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Male; Ophthalmic Solutions; Reflex, Pupillary; Sulfonamides; Thiophenes

2000
Latanoprost versus combined therapy with timolol plus dorzolamide: IOP-lowering effect in open-angle glaucoma.
    Acta ophthalmologica Scandinavica, 2001, Volume: 79, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2001
The hypotensive efficacy of dorzolamide HCL-timolol maleate 0.50% vs concomitant use of the two drugs.
    Acta ophthalmologica Scandinavica. Supplement, 2000, Issue:232

    Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Therapeutic Equivalency; Thiophenes; Timolol

2000
Comparison of the efficacy on intraocular pressure and retinal blood flow of a beta-blocker (timolol maleate) against the fixed association of a topical carbonic anhydrase (dorzolamide) and a beta-blocker (timolol maleate).
    Acta ophthalmologica Scandinavica. Supplement, 2000, Issue:232

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes; Timolol

2000
Hypotensive efficacy in primary open-angle glaucoma and ocular hypertension: latanoprost in monotherapy vs timolol and dorzolamide in association.
    Acta ophthalmologica Scandinavica. Supplement, 2000, Issue:232

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2000
Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension.
    Clinical therapeutics, 2001, Volume: 23, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Down-Regulation; Female; Glaucoma; Humans; Immunologic Factors; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes

2001
Intraindividual comparison of the effects of a fixed dorzolamide-timolol combination and latanoprost on intraocular pressure after small incision cataract surgery.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:5

    Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2001
[Ocular hemodynamics and visual field in glaucoma treated with dorzolamide].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:5

    Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Eye; Female; Follow-Up Studies; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Visual Fields

2001
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
    American journal of ophthalmology, 2001, Volume: 132, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome

2001
Treatment of intraocular pressure elevation after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:7

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorometholone; Glucocorticoids; Humans; Intraocular Pressure; Lasers, Excimer; Male; Ocular Hypertension; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2001
Comparison of the additive intraocular pressure-lowering effect of latanoprost and dorzolamide when added to timolol in patients with open-angle glaucoma or ocular hypertension: a randomized, open-label, multicenter study in Greece.
    Journal of glaucoma, 2001, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2001
Effect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucoma.
    American journal of ophthalmology, 2001, Volume: 132, Issue:4

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Indocyanine Green; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography; Visual Acuity

2001
[Clinical evaluation of isopropyl unoprostone (Rescula), in the adjunctive treatment of primary open angle glaucoma].
    Klinika oczna, 2001, Volume: 103, Issue:1

    Topics: Administration, Topical; Antihypertensive Agents; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol

2001
[Prevention of early postoperative increase in intraocular pressure after phacoemulsification. Comparison of different antiglaucoma drugs].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Polysaccharides, Bacterial; Postoperative Care; Postoperative Complications; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol

2001
Retrobulbar blood flow in glaucoma patients with nocturnal over-dipping in systemic blood pressure.
    American journal of ophthalmology, 2001, Volume: 132, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Sectional Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Artery; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color

2001
Dorzolamide and ocular blood flow in previously untreated glaucoma patients: a controlled double-masked study.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:2

    Topics: Administration, Topical; Aged; Aged, 80 and over; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Double-Blind Method; Eye; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color

2002
[Study on hypotensive effect of latanoprost vs timolol-dorzolamide association].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:4

    Topics: Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2002
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:3

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol

2002
The European glaucoma prevention study design and baseline description of the participants.
    Ophthalmology, 2002, Volume: 109, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Research Design; Safety; Sulfonamides; Thiophenes; Visual Acuity; Visual Field Tests; Visual Fields

2002
Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
    Acta ophthalmologica Scandinavica. Supplement, 2002, Volume: 236

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2002
The short-term IOP-lowering effect of brimonidine 0.2% and dorzolomide 2% combination in primary open-angle glaucoma.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes

2002
A comparison of the effects on intraocular pressure of latanoprost 0.005% and the fixed combination of dorzolamide 2% and timolol 0.5% in patients with open-angle glaucoma.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome

2002
Cost-minimisation study of dorzolamide versus brinzolamide in the treatment of ocular hypertension and primary open-angle glaucoma: in four European countries.
    PharmacoEconomics, 2003, Volume: 21, Issue:3

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Economics, Pharmaceutical; Europe; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes

2003
Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
    American journal of ophthalmology, 2003, Volume: 135, Issue:2

    Topics: Antihypertensive Agents; Cross-Over Studies; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity

2003
The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma.
    Eye (London, England), 2003, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Patient Satisfaction; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol

2003
Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.
    Ophthalmology, 2003, Volume: 110, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields

2003
Dorzolamide X apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy.
    Current eye research, 2002, Volume: 25, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clonidine; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Time Factors

2002
Acute and chronic ocular symptoms of dorzolamide 2% compared with placebo.
    Journal of glaucoma, 2003, Volume: 12, Issue:2

    Topics: Acute Disease; Adult; Carbonic Anhydrase Inhibitors; Chronic Disease; Double-Blind Method; Eye Diseases; Female; Humans; Male; Ophthalmic Solutions; Pain; Pain Measurement; Sulfonamides; Thiophenes; Time Factors

2003
The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:4

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2003
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol

2003
Short-term effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Corneal Diseases; Cross-Over Studies; Double-Blind Method; Endothelium, Corneal; Female; Humans; Hypertrophy; Interferometry; Light; Male; Middle Aged; Sulfonamides; Thiophenes

2003
The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:6

    Topics: Aged; Antihypertensive Agents; Choroid; Coloring Agents; Double-Blind Method; Female; Fluorescein Angiography; Humans; Indocyanine Green; Macular Degeneration; Male; Middle Aged; Retinal Vessels; Sulfonamides; Thiophenes

2003
The effect of topical glaucoma medications evaluated by perimetry.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:6

    Topics: Administration, Topical; Antihypertensive Agents; Betaxolol; Clonidine; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Levobunolol; Prospective Studies; Sulfonamides; Thiophenes; Visual Field Tests

2003
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
    Acta ophthalmologica Scandinavica, 2003, Volume: 81, Issue:4

    Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2003
Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination.
    Ophthalmology, 2003, Volume: 110, Issue:7

    Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2003
Replacing maximum-tolerated medications with latanoprost versus adding latanoprost to maximum-tolerated medications: a two-center randomized prospective trial.
    Journal of glaucoma, 2003, Volume: 12, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Retreatment; Single-Blind Method; Sulfonamides; Thiophenes

2003
Evaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patients.
    Acta ophthalmologica Scandinavica, 2003, Volume: 81, Issue:5

    Topics: Adrenergic beta-Antagonists; Arteries; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ophthalmoscopy; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Veins

2003
Effect of a fixed dorzolamide-timolol combination on intraocular pressure after small-incision cataract surgery with Viscoat.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Cataract Extraction; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Time Factors; Timolol

2003
A six-week, parallel, randomized, double-blind study comparing the efficacy and safety of the 0.5% timolol/2.0% MK-507 combination b.i.d. to the concomitant administration of 0.5% timolol b.i.d. and 2.0% MK-507 b.i.d.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:5

    Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Sulfonamides; Thiophenes; Timolol

2003
Efficacy and safety of brimonidine, dorzolamide and latanoprost as adjunctive therapy in primary open angle glaucoma.
    International journal of clinical practice, 2003, Volume: 57, Issue:10

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Child; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome

2003
The efficacy and safety of dose escalation of dorzolamide used in combination with other topical antiglaucoma agents.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Irritants; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins; Sulfonamides; Thiophenes; Time Factors

2003
Aqueous humor flow in normal human eyes treated with brimonidine and dorzolamide, alone and in combination.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:2

    Topics: Administration, Topical; Adult; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Cornea; Double-Blind Method; Drug Therapy, Combination; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes

2004
Short-term ocular tolerability of dorzolamide 2% and brinzolamide 1% vs placebo in primary open-angle glaucoma and ocular hypertension subjects.
    Eye (London, England), 2004, Volume: 18, Issue:9

    Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Sulfonamides; Thiazines; Thiophenes

2004
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure.
    Ophthalmology, 2004, Volume: 111, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2004
Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.
    Journal of glaucoma, 2004, Volume: 13, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2004
Comparison of the safety and efficacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension.
    Journal of glaucoma, 2004, Volume: 13, Issue:2

    Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome

2004
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
    Journal of glaucoma, 2004, Volume: 13, Issue:3

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

2004
[Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers].
    Archivos de la Sociedad Espanola de Oftalmologia, 2004, Volume: 79, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome

2004
Immediate postoperative use of a topical agent to prevent intraocular pressure elevation after pars plana vitrectomy with gas tamponade.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:5

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Fluorocarbons; Humans; Intraocular Pressure; Male; Middle Aged; Postoperative Complications; Postoperative Period; Prospective Studies; Retinal Detachment; Retinal Perforations; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy

2004
Comparison of additional intraocular pressure-lowering effects of latanoprost vs brimonidine in primary open-angle glaucoma patients with intraocular pressure uncontrolled by timolol-dorzolamide combination.
    Eye (London, England), 2005, Volume: 19, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2005
Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension.
    The British journal of ophthalmology, 2004, Volume: 88, Issue:7

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes

2004
Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%.
    Eye (London, England), 2004, Volume: 18, Issue:12

    Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2004
Comparison of latanoprost with fixed-combination dorzolamide and timolol in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label, parallel-group, multicenter study in Latin America.
    Clinical therapeutics, 2004, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2004
Comparing the fixed combination dorzolamide-timolol (Cosopt) to concomitant administration of 2% dorzolamide (Trusopt) and 0.5% timolol -- a randomized controlled trial and a replacement study.
    Journal of clinical pharmacy and therapeutics, 2004, Volume: 29, Issue:4

    Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Prospective Studies; Sulfonamides; Thiophenes; Timolol

2004
[Structural and immunohistochemical changes of conjunctiva induced by topical glaucoma medication].
    Oftalmologia (Bucharest, Romania : 1990), 2004, Volume: 48, Issue:1

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzalkonium Compounds; Betaxolol; Carbonic Anhydrase Inhibitors; Cloprostenol; Conjunctiva; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Immunohistochemistry; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Travoprost

2004
[Impact of prostaglandin-F(2alpha)-analogues and carbonic anhydrase inhibitors on central corneal thickness -- a cross-sectional study on 403 eyes].
    Klinische Monatsblatter fur Augenheilkunde, 2004, Volume: 221, Issue:9

    Topics: Acetazolamide; Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Collagen; Cornea; Corneal Topography; Cross-Sectional Studies; Dinoprost; Drug Therapy, Combination; Extracellular Matrix; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Travoprost; Ultrasonography

2004
Assessment of retinal hemodynamics with the Canon laser blood flowmeter after a single dose of 2% dorzolamide hydrochloride eyedrops.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2004, Volume: 39, Issue:5

    Topics: Administration, Topical; Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes

2004
[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients].
    Klinika oczna, 2004, Volume: 106, Issue:1-2 Suppl

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2004
A comparison of the effects of dorzolamide/timolol fixed combination versus latanoprost on intraocular pressure and pulsatile ocular blood flow in primary open-angle glaucoma patients.
    Acta ophthalmologica Scandinavica, 2004, Volume: 82, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Cross-Over Studies; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler

2004
Two-year follow-up of latanoprost 0.005% monotherapy after changing from previous glaucoma therapies.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2004, Volume: 20, Issue:6

    Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome

2004
Comparison of the efficacy and safety of dorzolamide 2% when added to brimonidine 0.2% or timolol maleate 0.5% in patients with primary open-angle glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2005
Results of the European Glaucoma Prevention Study.
    Ophthalmology, 2005, Volume: 112, Issue:3

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality Assurance, Health Care; Safety; Sulfonamides; Thiophenes; Treatment Outcome

2005
Topical dorzolamide increases pericentral visual function in age-related maculopathy: pilot study findings with short-wavelength automated perimetry.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:2

    Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Macular Degeneration; Male; Pilot Projects; Prospective Studies; Sulfonamides; Thiophenes; Visual Acuity; Visual Field Tests; Visual Fields

2005
24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects.
    Ophthalmology, 2005, Volume: 112, Issue:4

    Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Safety; Sulfonamides; Thiophenes; Visual Acuity

2005
Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428].
    BMC ophthalmology, 2005, Apr-05, Volume: 5

    Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Ciliary Arteries; Cloprostenol; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Latanoprost; Lipids; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Artery; Single-Blind Method; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color

2005
Dorzolamide influences the autoregulation of major retinal vessels caused by artificial intraocular pressure elevation in patients with POAG: a clinical study.
    Current eye research, 2005, Volume: 30, Issue:2

    Topics: Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Muscle, Smooth, Vascular; Ocular Hypertension; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation

2005
The efficacy and safety of topical brinzolamide and dorzolamide when added to the combination therapy of latanoprost and a beta-blocker in patients with glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Instillation, Drug; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Treatment Outcome

2005
Efficacy of the dorzolamide/timolol fixed combination versus latanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:3

    Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2005
A randomized trial assessing dorzolamide in patients with glaucoma who are younger than 6 years.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:9

    Topics: Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2005
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
    The British journal of ophthalmology, 2005, Volume: 89, Issue:10

    Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol

2005
The efficacy and ocular discomfort of substituting brinzolamide for dorzolamide in combination therapy with latanoprost, timolol, and dorzolamide.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:5

    Topics: Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision, Ocular

2005
Comparison of latanoprost monotherapy and combined therapy of 0.5% timolol and 1% dorzolamide in chronic primary angle-closure glaucoma (CACG) in Japanese patients.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:6

    Topics: Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Female; Glaucoma, Angle-Closure; Humans; Instillation, Drug; Intraocular Pressure; Japan; Latanoprost; Male; Ophthalmic Solutions; Patient Compliance; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2005
A comparison of the effects of 0.005% latanoprost and fixed combination dorzolamide/timolol on retrobulbar haemodynamics in previously untreated glaucoma patients.
    Current medical research and opinion, 2006, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2006
Comparative analysis of the efficacy and safety of latanoprost, travoprost and the fixed combination timolol-dorzolamide; a prospective, randomized, masked, cross-over design study.
    Oftalmologia (Bucharest, Romania : 1990), 2005, Volume: 49, Issue:3

    Topics: Aged; Antihypertensive Agents; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome

2005
Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa.
    American journal of ophthalmology, 2006, Volume: 141, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Diagnostic Techniques, Ophthalmological; Female; Humans; Macular Edema; Male; Middle Aged; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2006
Comparative analysis of the effects of brimonidine and dorzolamide on ocular blood flow velocity in patients with newly diagnosed primary open-angle glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:2

    Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Brimonidine Tartrate; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome; Ultrasonography, Doppler, Color

2006
The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma.
    American journal of ophthalmology, 2006, Volume: 141, Issue:6

    Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Ciliary Arteries; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Artery; Pilocarpine; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color

2006
Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:7

    Topics: Administration, Topical; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Circadian Rhythm; Diastole; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Perfusion; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2006
Additive effect of dorzolamide or carteolol to latanoprost in primary open-angle glaucoma: a prospective randomized crossover trial.
    Journal of glaucoma, 2006, Volume: 15, Issue:4

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carteolol; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome

2006
Comparison of the efficacy and safety of travoprost with a fixed-combination of dorzolamide and timolol in patients with open-angle glaucoma or ocular hypertension.
    Current medical research and opinion, 2006, Volume: 22, Issue:9

    Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Travoprost

2006
Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study.
    Ophthalmology, 2007, Volume: 114, Issue:1

    Topics: Antihypertensive Agents; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prognosis; Proportional Hazards Models; Risk Factors; Sulfonamides; Thiophenes; Visual Acuity

2007
A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Visual Acuity

2006
Central corneal thickness in the European Glaucoma Prevention Study.
    Ophthalmology, 2007, Volume: 114, Issue:3

    Topics: Adult; Age Factors; Aged; Cornea; Diabetes Complications; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sex Factors; Sulfonamides; Thiophenes; Ultrasonography

2007
Circadian intraocular pressure control with dorzolamide versus timolol maleate add-on treatments in primary open-angle glaucoma patients using latanoprost.
    Ophthalmic research, 2007, Volume: 39, Issue:1

    Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2007
Continued use of dorzolamide for the treatment of cystoid macular oedema in patients with retinitis pigmentosa.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:6

    Topics: Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Follow-Up Studies; Fovea Centralis; Humans; Macular Edema; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity

2007
Comparison of the ocular hypotensive effects of bimatoprost and timolol-dorzolamide combination in patients with elevated intraocular pressure: a 6-month study.
    Acta ophthalmologica Scandinavica, 2007, Volume: 85, Issue:1

    Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Timolol

2007
Retrobulbar haemodynamic effects of the latanoprost/timolol and the dorzolamide/timolol fixed combinations in newly diagnosed glaucoma patients.
    International journal of clinical practice, 2007, Volume: 61, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2007
Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.
    Current medical research and opinion, 2007, Volume: 23, Issue:4

    Topics: Aged; Brimonidine Tartrate; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol

2007
A comparison of latanoprost monotherapy with a combination therapy of timolol/dorzolamide in patients with primary open-angle glaucoma.
    Annals of ophthalmology (Skokie, Ill.), 2006,Summer, Volume: 38, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Eye Color; Eyelashes; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Prostaglandins F, Synthetic; Pruritus; Sulfonamides; Thiophenes; Timolol

2006
Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study.
    American journal of ophthalmology, 2007, Volume: 144, Issue:2

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Confidence Intervals; Cornea; Diuretics; Double-Blind Method; Europe; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Prevalence; Proportional Hazards Models; Retinal Hemorrhage; Retrospective Studies; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Treatment Outcome

2007
Ocular comfort of combination glaucoma therapies: brimonidine 0.2%/timolol 0.5% compared with dorzolamide 2%/timolol 0.5%.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:4

    Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Patient Compliance; Patient Satisfaction; Quinoxalines; Sulfonamides; Thiophenes; Timolol

2007
Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:10

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Capsulorhexis; Cataract; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Prosthesis Design; Sulfonamides; Thiophenes; Timolol

2007
Effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2007, Volume: 125, Issue:10

    Topics: Aged; Aged, 80 and over; Body Weights and Measures; Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Corneal Diseases; Corneal Edema; Cross-Over Studies; Double-Blind Method; Endothelium, Corneal; Female; Humans; Interferometry; Intraocular Pressure; Light; Male; Middle Aged; Sulfonamides; Thiophenes; Tonometry, Ocular

2007
Success rates for switching to dorzolamide/timolol fixed combination in timolol responders who are insufficiently controlled by latanoprost monotherapy.
    Acta ophthalmologica, 2008, Volume: 86, Issue:4

    Topics: Aged; Antihypertensive Agents; Cohort Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Satisfaction; Prospective Studies; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Treatment Outcome

2008
[Additive therapy with carboanhydrase inhibitors for open angle glaucoma previously treated with timolol 0.5% drops].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2007, Volume: 61, Issue:4

    Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Thiophenes; Timolol

2007
Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.
    Eye & contact lens, 2008, Volume: 34, Issue:1

    Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Postoperative Care; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2008
The effects of dorzolamide 2% and dorzolamide/timolol fixed combination on retinal and optic nerve head blood flow in primary open-angle glaucoma patients.
    Eye (London, England), 2008, Volume: 22, Issue:9

    Topics: Aged; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol

2008
Efficacy of the latanoprost versus timolol/dorzolamide combination therapy in patients with primary open angle glaucoma.
    Saudi medical journal, 2008, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2008
Effectiveness and safety of dorzolamide-timolol alone or combined with latanoprost in open-angle glaucoma or ocular hypertension.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Canada; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2008
A comparative study of the effects of brinzolamide and dorzolamide on retinal oxygen saturation and ocular microcirculation in patients with primary open-angle glaucoma.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Oxygen; Pilot Projects; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes; Visual Acuity

2008
Comparison of twice-daily and three-times-daily dosing of dorzolamide in ocular hypertension and primary open-angle glaucoma patients treated with latanoprost.
    Advances in therapy, 2008, Volume: 25, Issue:3

    Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes

2008
Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:10

    Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diastole; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2008
A comparison of dorzolamide/timolol-fixed combination versus bimatoprost in patients with open-angle glaucoma who are poorly controlled on latanoprost.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Amides; Bimatoprost; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2008
24-hour control of intraocular pressure with 2% dorzolamide/0.5% timolol fixed-combination ophthalmic solution in open-angle glaucoma.
    Current medical research and opinion, 2008, Volume: 24, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

2008
Effects of dorzolamide 2% added to timolol maleate 0.5% on intraocular pressure, retrobulbar blood flow, and the progression of visual field damage in patients with primary open-angle glaucoma: a single-center, 4-year, open-label study.
    Clinical therapeutics, 2008, Volume: 30, Issue:6

    Topics: Aged; Antihypertensive Agents; Disease Progression; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Fields

2008
Prolongation of activity of single intravitreal bevacizumab by adjuvant topical aqueous depressant (Timolol-Dorzolamide).
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009, Volume: 247, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aqueous Humor; Bevacizumab; Diabetic Retinopathy; Drug Synergism; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Macular Edema; Male; Middle Aged; Retinal Vein Occlusion; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity; Vitreous Body

2009
Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:11

    Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2008
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:6

    Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol

2008
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/
    Journal of glaucoma, 2008, Volume: 17, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult

2008
Efficacy and safety of latanoprost in eyes with uveitic glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009, Volume: 247, Issue:6

    Topics: Adult; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Uveitis, Anterior; Uveitis, Intermediate; Visual Acuity

2009
A comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patients.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:3

    Topics: Administration, Topical; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Ultrasonography, Doppler, Color

2009
Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.
    Current medical research and opinion, 2009, Volume: 25, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol

2009
Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs.
    Ophthalmology, 2009, Volume: 116, Issue:9

    Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Single-Blind Method; Sulfonamides; Thiazines; Thiophenes; Tonometry, Ocular; Travoprost; Treatment Outcome

2009
Comparison of effects of topical levobunolol to a combination of timolol-dorzolamide on intraocular pressure and pulse rate of healthy dogs.
    Veterinary research communications, 2009, Volume: 33 Suppl 1

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dogs; Drug Combinations; Female; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol

2009
Ocular blood flow and oxygen delivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy.
    Acta ophthalmologica, 2010, Volume: 88, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Oximetry; Oxygen; Regional Blood Flow; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color

2010
Predictors for visual field progression and the effects of treatment with dorzolamide 2% or brinzolamide 1% each added to timolol 0.5% in primary open-angle glaucoma.
    Acta ophthalmologica, 2010, Volume: 88, Issue:5

    Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Disease Progression; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Proportional Hazards Models; Prospective Studies; Retinal Artery; Risk Factors; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler, Color; Vision Disorders; Visual Fields

2010
Effect of dorzolamide and timolol on ocular pressure: blood flow relationship in patients with primary open-angle glaucoma and ocular hypertension.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:3

    Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Interferometry; Intraocular Pressure; Laser-Doppler Flowmetry; Lasers; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol

2010
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
    Eye (London, England), 2010, Volume: 24, Issue:7

    Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields

2010
Fixed-combination brimonidine/timolol as adjunctive therapy to a prostaglandin analog: a 3-month, open-label, replacement study in glaucoma patients.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:6

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Hypersensitivity; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol

2009
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.
    Current medical research and opinion, 2010, Volume: 26, Issue:7

    Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol

2010
The additive effect of dorzolamide hydrochloride (Trusopt) and a morning dose of bimatoprost (Lumigan) on intraocular pressure and retrobulbar blood flow in patients with primary open-angle glaucoma.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Cloprostenol; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Orbit; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes

2010
Comparison of the effects of dorzolamide/timolol and latanoprost/timolol fixed combinations upon intraocular pressure and progression of visual field damage in primary open-angle glaucoma.
    Current medical research and opinion, 2010, Volume: 26, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Disease Progression; Dosage Forms; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Fields

2010
Effects of topical 0.5% levobunolol alone or in association with 2% dorzolamide compared with a fixed combination of 0.5% timolol and 2% dorzolamide on intraocular pressure and heart rate in dogs without glaucoma.
    Veterinary therapeutics : research in applied veterinary medicine, 2010,Fall, Volume: 11, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Dogs; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol

2010
Intraocular pressure and ocular hemodynamics in patients with primary open-angle glaucoma treated with the combination of morning dosing of bimatoprost and dorzolamide hydrochloride.
    Acta ophthalmologica, 2011, Volume: 89, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Blood Pressure; Circadian Rhythm; Cloprostenol; Drug Administration Schedule; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Retinal Artery; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Ultrasonography, Doppler, Color

2011
[Comparative study of the pressure lowering efficacy and variations in the ocular pulse amplitude between fixed combinations of dorzolamide/timolol and brinzolamide/timolol].
    Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:5

    Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Pulse; Sulfonamides; Thiazines; Thiophenes; Timolol; Young Adult

2011
From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:16

    Topics: Aged; Antihypertensive Agents; Diagnostic Techniques, Ophthalmological; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiazines; Thiophenes; Timolol

2011
[Double-masked, phase III comparative study of the combination ophthalmic solution of the 1% dorzolamide hydrochloride/0.5% timolol maleate (MK-0507A) in patients with glaucoma and ocular hypertension].
    Nippon Ganka Gakkai zasshi, 2011, Volume: 115, Issue:6

    Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

2011
Pharmacodynamic equivalence study of two preparations of eye drops containing dorzolamide and timolol in healthy volunteers.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:5

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Eye Movements; Female; Fundus Oculi; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pupil; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Visual Acuity; Young Adult

2011
Diurnal intraocular pressure efficacy of the timolol-brimonidine fixed combination and the timolol-dorzolamide fixed combination as a first choice therapy in patients with pseudoexfoliation glaucoma.
    Current eye research, 2011, Volume: 36, Issue:9

    Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Single-Blind Method; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Acuity

2011
Comparison of dorzolamide/timolol and latanoprost/timolol fixed combinations on diurnal intraocular pressure control in primary open-angle glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Optic Disk; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2012
Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:6

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cornea; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sphygmomanometers; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography

2012
Fixed topical combinations in glaucomatous patients and ocular discomfort.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:13

    Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Benzalkonium Compounds; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Preservatives, Pharmaceutical; Prospective Studies; Single-Blind Method; Sulfonamides; Suspensions; Thiazines; Thiophenes; Time Factors; Timolol

2012
Three-month evaluation of dorzolamide hydrochloride/timolol maleate fixed-combination eye drops versus the separate use of both drugs.
    Japanese journal of ophthalmology, 2012, Volume: 56, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular

2012
The Heidelberg retina tomograph ancillary study to the European glaucoma prevention study: study design and baseline factors.
    Acta ophthalmologica, 2013, Volume: 91, Issue:8

    Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmoscopy; Optic Disk; Optic Nerve Diseases; Research Design; Sulfonamides; Thiophenes; Tomography; Tonometry, Ocular; Visual Acuity; Visual Fields

2013
Comparison of dorzolamide/timolol versus brimonidine/timolol fixed combination therapy in the management of steroid-induced ocular hypertension.
    Journal of glaucoma, 2015, Volume: 24, Issue:2

    Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Diabetic Retinopathy; Drug Combinations; Female; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Triamcinolone Acetonide

2015
γ-Cyclodextrin nanoparticle eye drops with dorzolamide: effect on intraocular pressure in man.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Delivery Systems; Female; gamma-Cyclodextrins; Humans; Intraocular Pressure; Male; Nanoparticles; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Visual Acuity

2014
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluid.
    Acta ophthalmologica, 2014, Volume: 92, Issue:6

    Topics: Biological Availability; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Dexamethasone; Double-Blind Method; Female; gamma-Cyclodextrins; Glucocorticoids; Humans; Male; Nanoparticles; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Suspensions; Tandem Mass Spectrometry; Tears; Thiophenes; Tissue Distribution

2014
Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes.
    Ophthalmology, 2014, Volume: 121, Issue:9

    Topics: Adult; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Logistic Models; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Acuity

2014
Effect of topical aqueous suppression on intraocular gas duration after pure perfluoropropane injection in nonvitrectomized eyes with retinal detachment.
    Retina (Philadelphia, Pa.), 2014, Volume: 34, Issue:12

    Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cryotherapy; Drug Combinations; Endotamponade; Fluorocarbons; Humans; Injections, Intraocular; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinal Detachment; Scleral Buckling; Sulfonamides; Thiophenes; Time Factors; Timolol; Vitrectomy

2014
Comparison of topical dorzolamide and ketorolac treatment for cystoid macular edema in retinitis pigmentosa and Usher's syndrome.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2015, Volume: 233, Issue:1

    Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Female; Fovea Centralis; Humans; Ketorolac Tromethamine; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Usher Syndromes; Visual Acuity; Visual Field Tests; Visual Fields; Young Adult

2015
Effect of topical ophthalmic dorzolamide(2%)-timolol(0.5%) solution and ointment on intraocular pressure in normal horses.
    Veterinary ophthalmology, 2015, Volume: 18, Issue:6

    Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Ointments; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2015
Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study.
    BMC ophthalmology, 2014, Dec-19, Volume: 14

    Topics: Administration, Topical; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome

2014
Latanoprost and Dorzolamide for the Treatment of Pediatric Glaucoma: The Glaucoma Italian Pediatric Study (Gipsy), Design and Baseline Characteristics.
    Advances in therapy, 2016, Volume: 33, Issue:8

    Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome

2016
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
    European journal of ophthalmology, 2017, Mar-10, Volume: 27, Issue:2

    Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome

2017
Effects of perioperative topical dorzolamide hydrochloride-timolol maleate administration on incidence and severity of postoperative ocular hypertension in dogs undergoing cataract extraction by phacoemulsification.
    Journal of the American Veterinary Medical Association, 2016, Nov-01, Volume: 249, Issue:9

    Topics: Animals; Antihypertensive Agents; Cataract Extraction; Dog Diseases; Dogs; Drug Combinations; Ocular Hypertension; Perioperative Care; Postoperative Complications; Sulfonamides; Thiophenes; Timolol

2016
Dorzolamide nanoliposome as a long action ophthalmic delivery system in open angle glaucoma and ocular hypertension patients.
    Drug development and industrial pharmacy, 2018, Volume: 44, Issue:8

    Topics: Antihypertensive Agents; Cornea; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Liposomes; Nanoparticles; Ocular Hypertension; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes; Time Factors

2018
The Glaucoma Italian Pediatric Study (GIPSy): 1-Year Results.
    Journal of glaucoma, 2017, Volume: 26, Issue:11

    Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prognosis; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome

2017
The Glaucoma Italian Pediatric Study (GIPSy): 3-Year Results.
    Journal of glaucoma, 2018, Volume: 27, Issue:10

    Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome

2018
The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
    Veterinary ophthalmology, 2020, Volume: 23, Issue:1

    Topics: Animals; Cats; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Sulfonamides; Thiazines; Thiophenes; Timolol

2020
Dilatation of Retinal Arterioles Induced by Topical Dorzolamide for One Week Is Impaired in Patients with Type 1 Diabetes and Mild Retinopathy.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2020, Volume: 243, Issue:3

    Topics: Administration, Ophthalmic; Adult; Arterioles; Blood Pressure; Carbonic Anhydrase Inhibitors; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Homeostasis; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation

2020
Combination of Intravitreal Bevacizumab and Topical Dorzolamide versus Intravitreal Bevacizumab Alone for Diabetic Macular Edema: A Randomized Contralateral Clinical Trial.
    BioMed research international, 2020, Volume: 2020

    Topics: Administration, Topical; Aged; Bevacizumab; Diabetic Retinopathy; Female; Humans; Intravitreal Injections; Iran; Macular Edema; Male; Middle Aged; Sulfonamides; Thiophenes

2020
The Glaucoma Italian Pediatric Study (GIPSy): The Long-term Effect of Topical Latanoprost on Central Corneal Thickness.
    Journal of glaucoma, 2020, Volume: 29, Issue:6

    Topics: Administration, Topical; Adolescent; Age of Onset; Antihypertensive Agents; Child; Child, Preschool; Cornea; Corneal Pachymetry; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Long-Term Care; Male; Organ Size; Sulfonamides; Thiophenes; Time Factors; Tonometry, Ocular

2020
Hypokalemia associated with topical administration of dorzolamide 2% ophthalmic solution in cats.
    Veterinary ophthalmology, 2021, Volume: 24, Issue:1

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cat Diseases; Cats; Double-Blind Method; Female; Hypokalemia; Male; Ophthalmic Solutions; Potassium; Proof of Concept Study; Prospective Studies; Retrospective Studies; Sulfonamides; Thiophenes

2021
Corneal epithelium and limbal region alterations due to glaucoma medications evaluated by anterior segment optic coherence tomography: a case-control study.
    Cutaneous and ocular toxicology, 2021, Volume: 40, Issue:2

    Topics: Aged; Antihypertensive Agents; Benzalkonium Compounds; Brimonidine Tartrate; Case-Control Studies; Epithelium, Corneal; Female; Glaucoma; Humans; Latanoprost; Limbus Corneae; Male; Middle Aged; Ophthalmic Solutions; Preservatives, Pharmaceutical; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence

2021
Comparing the effects and safety of dorzolamide hydrochloride + timolol maleate versus brimonidine after neodymium-doped yttrium aluminium garnet laser capsulotomy posterior capsule opacification.
    European journal of ophthalmology, 2022, Volume: 32, Issue:5

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lasers, Solid-State; Neodymium; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Yttrium

2022

Other Studies

353 other study(ies) available for thiophenes and dorzolamide

ArticleYear
Indirect chiral separation and analyses in human biological fluids of the stereoisomers of a thienothiopyran-2-sulfonamide (TRUSOPT), a novel carbonic anhydrase inhibitor with two chiral centers in the molecule.
    Chirality, 1992, Volume: 4, Issue:8

    Topics: Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Ophthalmic Solutions; Stereoisomerism; Sulfonamides; Thiophenes

1992
MK-507 (L-671,152), a topically active carbonic anhydrase inhibitor, reduces aqueous humor production in monkeys.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:9

    Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Female; Fluorophotometry; Intraocular Pressure; Macaca fascicularis; Sulfonamides; Thiophenes; Tonometry, Ocular

1991
Topically active carbonic anhydrase inhibitors for glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:1

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sulfonamides; Thiophenes

1991
A comparison of L-671,152 and MK-927, two topically effective ocular hypotensive carbonic anhydrase inhibitors, in experimental animals.
    Current eye research, 1990, Volume: 9, Issue:6

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chymotrypsin; Ciliary Body; Erythrocytes; Female; In Vitro Techniques; Iris; Light Coagulation; Macaca fascicularis; Male; Ocular Hypertension; Ocular Hypotension; Rabbits; Sulfonamides; Thiophenes; Trabeculectomy

1990
The ocular hypotensive effect of the topical carbonic anhydrase inhibitor L-671,152 in glaucomatous monkeys.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:4

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Female; Glaucoma; Intraocular Pressure; Laser Therapy; Macaca fascicularis; Molecular Structure; Sulfonamides; Thiophenes

1990
Preclinical studies on L-671,152, a topically effective ocular hypotensive carbonic anhydrase inhibitor.
    British journal of pharmacology, 1989, Volume: 98 Suppl

    Topics: Animals; Carbonic Anhydrase Inhibitors; Intraocular Pressure; Macaca fascicularis; Ophthalmic Solutions; Sulfonamides; Thiophenes

1989
[The time required topical carbonic anhydrase inhibitor (MK-507) to take effect on intraocular pressure of normal human eyes].
    Nippon Ganka Gakkai zasshi, 1995, Volume: 99, Issue:9

    Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Depression, Chemical; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Time Factors

1995
Effect of MK-507 on aqueous humor dynamics in normal human eyes.
    Japanese journal of ophthalmology, 1994, Volume: 38, Issue:1

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Eye Proteins; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes

1994
Analytical chiral separation of the stereoisomers of a novel carbonic anhydrase inhibitor and its deethylated metabolite, and the assignment of absolute configuration of the human metabolite and chiral degradation products.
    Pharmaceutical research, 1994, Volume: 11, Issue:3

    Topics: Biotransformation; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Humans; Molecular Conformation; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfonamides; Thiophenes

1994
Determination of MK-507, a novel topically effective carbonic anhydrase inhibitor, and its de-ethylated metabolite in human whole blood, plasma, and urine by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1994, Feb-18, Volume: 653, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Dealkylation; Humans; Indicators and Reagents; Ophthalmic Solutions; Reference Standards; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes

1994
[Effect of topical carbonic anhydrase inhibitor (MK-507) on intraocular pressure of normal human eyes].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:3

    Topics: Acetazolamide; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Depression, Chemical; Eye Proteins; Humans; Intraocular Pressure; Sulfonamides; Thiophenes

1994
Topical dorzolamide-induced hypotony and ciliochoroidal detachment in patients with previous filtration surgery.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:8

    Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Choroid Diseases; Ciliary Body; Female; Filtering Surgery; Glaucoma; Humans; Intraocular Pressure; Ocular Hypotension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Ultrasonography; Uveal Diseases

1996
New therapeutic agents marketed in 1995.
    Pennsylvania medicine, 1996, Volume: 99, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acarbose; Alendronate; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carbonic Anhydrase Inhibitors; Drug Approval; Enzyme Inhibitors; Hypoglycemic Agents; Lansoprazole; Metformin; Omeprazole; Pregnadienes; Sulfonamides; Thiophenes; Trisaccharides; United States; United States Food and Drug Administration

1996
[Successful pressure decrease and improved patient quality of life by Trusopt].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 208, Issue:4

    Topics: Adult; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes

1996
Nonlinear dorzolamide pharmacokinetics in rats: concentration-dependent erythrocyte distribution and drug-metabolite displacement interaction.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:6

    Topics: Administration, Oral; Analysis of Variance; Animals; Carbonic Anhydrase Inhibitors; Erythrocytes; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes

1996
Membrane-bound carbonic anhydrase activity in the rat corneal endothelium and retina.
    Japanese journal of ophthalmology, 1996, Volume: 40, Issue:2

    Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane; Cobalt; Endothelium, Corneal; Histocytochemistry; Male; Membrane Proteins; Rats; Rats, Wistar; Retina; Sulfonamides; Thiophenes

1996
[Glaucoma. Current problems. Continuing education courses at the Ophthalmologic Clinic of the Eppendorf University Hospital, 9 December 1995].
    Klinische Monatsblatter fur Augenheilkunde, 1996, Volume: 208, Issue:2 Suppl

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sulfonamides; Thiophenes

1996
Ocular absorption, blood levels, and excretion of dorzolamide, a topically active carbonic anhydrase inhibitor.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:1

    Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes

1997
Continuous intraocular pressure measurement by telemetry in alpha-chymotrypsin-induced glaucoma model in the rabbit: effects of timolol, dorzolamide, and epinephrine.
    Journal of pharmacological and toxicological methods, 1996, Volume: 36, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chymotrypsin; Circadian Rhythm; Disease Models, Animal; Epinephrine; Female; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol

1996
[Carbonic anhydrase inhibitors with topical action in the treatment of glaucomatous diseases. A preliminary note].
    Oftalmologia (Bucharest, Romania : 1990), 1997, Volume: 41, Issue:1

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Combined Modality Therapy; Corneal Edema; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Time Factors

1997
Low level determination of dorzolamide and its de-ethylated metabolite in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:7

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes

1997
[Effectiveness of dorzolamide as added therapy in glaucoma patients with maximum tolerated drug therapy. A pilot study].
    Klinische Monatsblatter fur Augenheilkunde, 1997, Volume: 210, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes; Treatment Outcome

1997
An unusual side effect of Dorzolamide.
    Eye (London, England), 1997, Volume: 11 ( Pt 3)

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chemical Precipitation; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Sulfonamides; Thiophenes

1997
[Ocular pulse amplitude and local carbonic anhydrase inhibition].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1997, Volume: 94, Issue:9

    Topics: Adult; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes

1997
Development and pharmacological characterization of a modified procedure for the measurement of carbonic anhydrase activity.
    Journal of pharmacological and toxicological methods, 1997, Volume: 38, Issue:3

    Topics: Acetazolamide; Animals; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cattle; Hydrogen-Ion Concentration; Isoenzymes; Kidney; Sulfonamides; Thiophenes

1997
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:1

    Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol

1998
2% dorzolamide and cornea: an ultrabiomicroscopic study.
    Acta ophthalmologica Scandinavica. Supplement, 1997, Issue:224

    Topics: Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Endothelium, Corneal; Glaucoma, Open-Angle; Humans; Image Processing, Computer-Assisted; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Ultrasonography; Visual Acuity

1997
[Trusopt, a local carboanhydrase inhibitor, in the treatment of glaucoma in children (preliminary report)].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 1998, Volume: 54, Issue:2

    Topics: Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Female; Glaucoma; Humans; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes

1998
The effect of aqueous humor suppressants on intravitreal gas bubble duration in rabbits.
    American journal of ophthalmology, 1998, Volume: 125, Issue:5

    Topics: Absorption; Administration, Topical; Animals; Aqueous Humor; Clonidine; Fluorocarbons; Injections; Intraocular Pressure; Rabbits; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Time Factors; Timolol; Vitreous Body

1998
[Glaucoma in the elderly].
    Soins. Gerontologie, 1998, Issue:12

    Topics: Aged; Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Trabeculectomy

1998
Glaucomatocyclitic crisis in a child.
    American journal of ophthalmology, 1998, Volume: 126, Issue:1

    Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Male; Pain; Prednisolone; Sulfonamides; Syndrome; Thiophenes; Timolol; Uveitis, Intermediate; Vision Disorders; Visual Acuity

1998
Dorzolamide and timolol as suppressors of aqueous humor flow.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:8

    Topics: Adrenergic beta-Antagonists; Aqueous Humor; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Sleep; Sulfonamides; Thiophenes; Timolol

1998
Update in glaucoma: the new pharmacotherapies. Dorzolamide hydrochloride.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1998, Volume: 33, Issue:5

    Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes

1998
[New drugs in glaucoma therapy].
    Klinische Monatsblatter fur Augenheilkunde, 1998, Volume: 213, Issue:1

    Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome

1998
[Treatment of glaucoma with carbonic anhydrase inhibitors in eyewash: medium term retrospective experience with dorzolamide].
    Bulletin de la Societe belge d'ophtalmologie, 1997, Volume: 267

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Female; Glaucoma; Humans; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes

1997
Combination of systemic acetazolamide and topical dorzolamide.
    Ophthalmology, 1998, Volume: 105, Issue:9

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiophenes

1998
Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV with N-hydroxysulfonamides--a novel class of intraocular pressure lowering agents.
    Journal of enzyme inhibition, 1998, Volume: 13, Issue:4

    Topics: Acetamides; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Glaucoma; Humans; Hydroxylamines; Intraocular Pressure; Isoenzymes; Male; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids; Thiophenes; Tosyl Compounds

1998
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:12

    Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular

1998
Contact allergy to dorzolamide eyedrops.
    Contact dermatitis, 1998, Volume: 39, Issue:4

    Topics: Antihypertensive Agents; Dermatitis, Allergic Contact; Female; Glaucoma; Humans; Middle Aged; Ophthalmic Solutions; Patch Tests; Skin; Sulfonamides; Thiophenes

1998
[Modern anti-glaucoma drugs and their secondary effects].
    Revue medicale de la Suisse romande, 1998, Volume: 118, Issue:11

    Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Dinoprost; Glaucoma; Humans; Quinoxalines; Sulfonamides; Thiophenes

1998
Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:1

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Hydrogen-Ion Concentration; Injections, Intravenous; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Tonometry, Ocular

1999
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
    Nederlands tijdschrift voor geneeskunde, 1999, Jan-30, Volume: 143, Issue:5

    Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Approval; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Netherlands; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes

1999
Regulation of intraocular pressure after water drinking.
    Journal of glaucoma, 1999, Volume: 8, Issue:2

    Topics: Aqueous Humor; Blood-Aqueous Barrier; Carbonic Anhydrase Inhibitors; Drinking; Follow-Up Studies; Humans; Intraocular Pressure; Ophthalmic Solutions; Osmosis; Reference Values; Sulfonamides; Thiophenes

1999
Irreversible corneal decompensation in patients treated with topical dorzolamide.
    American journal of ophthalmology, 1999, Volume: 127, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Corneal Edema; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Male; Middle Aged; Ophthalmic Solutions; Refractive Errors; Retrospective Studies; Sulfonamides; Thiophenes; Visual Acuity

1999
Non-invasive assessment of ocular pharmacokinetics using Confocal Raman Spectroscopy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:2

    Topics: Animals; Eye; Female; Rabbits; Spectrum Analysis, Raman; Sulfonamides; Thiophenes

1999
Anorexia, depression and dementia induced by dorzolamide eyedrops (Trusopt).
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1999, Volume: 34, Issue:2

    Topics: Aged; Anorexia; Carbonic Anhydrase Inhibitors; Dementia; Depression; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Visual Acuity

1999
[Is corneal thickness measurement reliable and useful?].
    Journal francais d'ophtalmologie, 1999, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Cornea; Corneal Transplantation; Diabetes Mellitus; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Observer Variation; Ocular Hypertension; Reproducibility of Results; Sulfonamides; Thiophenes; Ultrasonography

1999
Population pharmacokinetics of 2% topical dorzolamide in the aqueous humor of humans.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:7

    Topics: Absorption; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cataract Extraction; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes

1999
Clinical estimation of corneal endothelial pump function.
    Transactions of the American Ophthalmological Society, 1998, Volume: 96

    Topics: Administration, Topical; Adolescent; Adult; Body Water; Contact Lenses; Corneal Edema; Corneal Transplantation; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endothelium, Corneal; Humans; Permeability; Reference Values; Sulfonamides; Thiophenes

1998
Dorzolamide-timolol combination versus concomitant administration of its components.
    Ophthalmology, 1999, Volume: 106, Issue:6

    Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Timolol

1999
Carbonic anhydrase inhibitors. Part 71. Synthesis and ocular pharmacology of a new class of water-soluble, topically effective intraocular pressure lowering sulfonamides incorporating picolinoyl moieties.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 8, Issue:4

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbodiimides; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Humans; Intraocular Pressure; Male; Picolinic Acids; Rabbits; Solubility; Sulfonamides; Thiophenes; Water

1999
Nephrolithiasis with dorzolamide.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Kidney; Kidney Calculi; Male; Sulfonamides; Thiophenes

1999
The effectiveness and safety of dorzolamide 2% in addition to multiple topical antiglaucoma medications.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes

1999
Neurobiological and psychophysical mechanisms underlying the oral sensation produced by carbonated water.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Sep-15, Volume: 19, Issue:18

    Topics: Action Potentials; Adult; Animals; Brain Stem; Carbonated Beverages; Carbonic Anhydrase Inhibitors; Electrophysiology; Female; Functional Laterality; Humans; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sensation; Sulfonamides; Thiophenes; Tongue; Trigeminal Nuclei

1999
The effects of the carbonic anhydrase inhibitors methazolamide, diclofenamide and dorzolamide on trabecular meshwork and ciliary muscle contractility.
    Experimental eye research, 1999, Volume: 69, Issue:4

    Topics: Animals; Carbonic Anhydrase Inhibitors; Cattle; Ciliary Body; Dichlorphenamide; Methazolamide; Muscle Contraction; Sulfonamides; Thiophenes; Trabecular Meshwork

1999
Optic nerve oxygen tension in pigs and the effect of carbonic anhydrase inhibitors.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:11

    Topics: Acetazolamide; Animals; Blood Gas Analysis; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Injections, Intravenous; Ion-Selective Electrodes; Optic Disk; Optic Nerve; Oxygen; Oxygen Consumption; Polarography; Sulfonamides; Swine; Thiophenes

1999
Sterile mucopurulent conjunctivitis associated with the use of dorzolamide eyedrops.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:10

    Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Conjunctiva; Conjunctivitis; Female; Glaucoma, Angle-Closure; Humans; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes

1999
Irreversible corneal decompensation in patients treated with topical dorzolamide.
    American journal of ophthalmology, 1999, Volume: 128, Issue:6

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Corneal Edema; Glaucoma; Humans; Sulfonamides; Thiophenes

1999
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification. 1999; 43 (5): 344-6.
    Journal of the Royal College of Surgeons of Edinburgh, 1999, Volume: 44, Issue:6

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Humans; Intraocular Pressure; Phacoemulsification; Postoperative Complications; Sulfonamides; Thiophenes

1999
Ultratrace analysis of drugs in biological fluids using affinity probe capillary electrophoresis: analysis of dorzolamide with fluorescently labeled carbonic anhydrase.
    Electrophoresis, 2000, Volume: 21, Issue:1

    Topics: Animals; Body Fluids; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Electrophoresis, Capillary; Humans; Sensitivity and Specificity; Sulfonamides; Thiophenes

2000
Delayed, recurrent hypotonous maculopathy following aqueous suppressant therapy in pseudophakia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1999, Volume: 34, Issue:7

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Macula Lutea; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prednisolone; Prodrugs; Pseudophakia; Recurrence; Retinal Diseases; Sulfonamides; Thiophenes; Ultrasonography

1999
Increased optic nerve head blood flow after 1 week of twice daily topical brinzolamide treatment in Dutch-belted rabbits.
    Survey of ophthalmology, 2000, Volume: 44 Suppl 2

    Topics: Animals; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Hemodynamics; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Ophthalmic Solutions; Optic Disk; Rabbits; Sulfonamides; Thiazines; Thiophenes

2000
PHARMAC complicates treatment of glaucoma.
    The New Zealand medical journal, 1999, Nov-12, Volume: 112, Issue:1099

    Topics: Antihypertensive Agents; Glaucoma; Government Agencies; Humans; Latanoprost; New Zealand; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes

1999
Interactions between carbonic anhydrase and its inhibitors revealed by gel electrophoresis and circular dichroism.
    Electrophoresis, 2000, Volume: 21, Issue:8

    Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Methazolamide; Sodium Dodecyl Sulfate; Sulfonamides; Thiophenes; Titrimetry; Urea

2000
Comparison of the efficacy and safety of latanoprost 0.005% compared to brimonidine 0.2% or dorzolamide 2% when added to a topical beta-adrenergic blocker in patients with primary open-angle glaucoma or ocular hypertension.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Tonometry, Ocular

2000
Bullous pemphigoid possibly triggered and exacerbated by ophthalmic preparations.
    International journal of dermatology, 2000, Volume: 39, Issue:7

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diabetes Mellitus, Type 2; Glaucoma; Humans; Levobunolol; Male; Middle Aged; Mouth Mucosa; Ophthalmic Solutions; Pemphigoid, Bullous; Sulfonamides; Thiophenes; Timolol

2000
Optic nerve oxygen tension: effects of intraocular pressure and dorzolamide.
    The British journal of ophthalmology, 2000, Volume: 84, Issue:9

    Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Infusions, Intravenous; Intraocular Pressure; Optic Nerve; Oxygen; Sulfonamides; Swine; Thiophenes

2000
Marginal keratitis: an uncommon form of topical dorzolamide allergy.
    American journal of ophthalmology, 2000, Volume: 130, Issue:1

    Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Keratitis; Ophthalmic Solutions; Sulfonamides; Thiophenes

2000
[Central corneal thickness in normal eyes, patients with ocular hypertension, normal-pressure and open-angle glaucomas--a clinical study].
    Klinische Monatsblatter fur Augenheilkunde, 2000, Volume: 217, Issue:4

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cornea; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Reference Values; Sex Distribution; Sulfonamides; Thiophenes

2000
Comparison of the ocular hypotensive effect of brimonidine, dorzolamide, latanoprost, or artificial tears added to timolol in glaucomatous monkey eyes.
    Journal of glaucoma, 2000, Volume: 9, Issue:6

    Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Intraocular Pressure; Latanoprost; Macaca fascicularis; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Random Allocation; Sulfonamides; Thiophenes; Timolol

2000
[Dorzolamide: hypotensive efficacy in combination with beta-blockers. Long-term results].
    Archivos de la Sociedad Espanola de Oftalmologia, 2000, Volume: 75, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma; Humans; Male; Retrospective Studies; Sulfonamides; Thiophenes; Time Factors

2000
[Effect of Trusopt on normal intraocular pressure values in children].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2000, Volume: 56, Issue:6

    Topics: Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Humans; Intraocular Pressure; Sulfonamides; Thiophenes

2000
Effect of topical administration of 2% dorzlamide hydrochloride or 2% dorzlamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses.
    American journal of veterinary research, 2001, Volume: 62, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chemistry, Pharmaceutical; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Random Allocation; Regression Analysis; Sulfonamides; Thiophenes; Timolol

2001
Carbonic anhydrase inhibitors: synthesis and inhibition against isozymes I, II and IV of topically acting antiglaucoma sulfonamides incorporating cis-5-norbornene-endo-3-carboxy-2-carboxamido moieties.
    Journal of enzyme inhibition, 2001, Volume: 16, Issue:2

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Escherichia coli; Glaucoma; Humans; Indicators and Reagents; Isoenzymes; Kinetics; Norbornanes; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes

2001
[Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District].
    Klinika oczna, 2000, Volume: 102, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Disease Progression; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Office Visits; Pilocarpine; Poland; Sulfonamides; Thiophenes; Timolol

2000
Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs.
    Veterinary ophthalmology, 2001, Volume: 4, Issue:1

    Topics: Administration, Oral; Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Administration Schedule; Female; Glaucoma; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Sulfonamides; Thiophenes; Treatment Outcome

2001
Effects of topical application of a 2% solution of dorzolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs.
    American journal of veterinary research, 2001, Volume: 62, Issue:6

    Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Dogs; Female; Fluorophotometry; Glaucoma; Intraocular Pressure; Male; Random Allocation; Sulfonamides; Thiophenes

2001
Allergic contact dermatitis due to dorzolamide eyedrops.
    Contact dermatitis, 2001, Volume: 45, Issue:1

    Topics: Antihypertensive Agents; Conjunctivitis, Allergic; Dermatitis, Allergic Contact; Diagnosis, Differential; Glaucoma; Humans; Male; Middle Aged; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes

2001
[Severe hyperglycemia caused by dorzolamide].
    Archivos de la Sociedad Espanola de Oftalmologia, 2001, Volume: 76, Issue:6

    Topics: Antihypertensive Agents; Female; Humans; Hyperglycemia; Middle Aged; Severity of Illness Index; Sulfonamides; Thiophenes

2001
[Additive effects of topical carbonic anhydrase inhibitors].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2001, Volume: 57, Issue:4

    Topics: Aged; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2001
Drug points. Exacerbation of angina associated with latanoprost.
    BMJ (Clinical research ed.), 2001, Oct-06, Volume: 323, Issue:7316

    Topics: Acute Disease; Aged; Angina Pectoris; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Vasoconstrictor Agents

2001
Allergic contact blepharoconjunctivitis from dorzolamide.
    Contact dermatitis, 2001, Volume: 45, Issue:4

    Topics: Aged; Blepharitis; Carbonic Anhydrase Inhibitors; Conjunctivitis, Allergic; Dermatitis, Allergic Contact; Glaucoma; Humans; Male; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes

2001
[Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:10

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Rabbits; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol

2001
[The pH reaction in aqueous humor to antiglaucoma agents of various concentrations and pH levels].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2001, Volume: 57, Issue:5

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aqueous Humor; Female; Glaucoma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Male; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2001
Refractive change after dorzolamide use in patients with primary open-angle glaucoma and ocular hypertension.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2001, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Refractive Errors; Sulfonamides; Thiophenes

2001
Application of TLC-densitometry, first-derivative UV-spectrophotometry and ratio derivative spectrophotometry for the determination of dorzolamide hydrochloride and timolol maleate.
    Journal of pharmaceutical and biomedical analysis, 2002, Feb-01, Volume: 27, Issue:5

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chromatography, Thin Layer; Densitometry; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes; Timolol

2002
Periorbital dermatitis as a side effect of topical dorzolamide.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Eruptions; Facial Dermatoses; Female; Glaucoma; Humans; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes

2002
Simultaneous determination of dorzolamide HCL and timolol maleate in eye drops by two different spectroscopic methods.
    Journal of pharmaceutical and biomedical analysis, 2002, Apr-15, Volume: 28, Issue:2

    Topics: Adrenergic beta-Antagonists; Algorithms; Antihypertensive Agents; Calibration; Drug Combinations; Ophthalmic Solutions; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes; Timolol

2002
Rapid high-performance liquid chromatographic assay of dorzolamide in rabbit aqueous humor.
    Biomedical chromatography : BMC, 2002, Volume: 16, Issue:4

    Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Male; Rabbits; Sulfonamides; Thiophenes

2002
[Corneal descompensation in patients with endothelial compromise treated with topical dorzolamide].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cornea; Endothelium, Corneal; Filtering Surgery; Glaucoma; Humans; Keratoplasty, Penetrating; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes; Vitrectomy

2002
The effects of new topical treatments on management of glaucoma in Scotland: an examination of ophthalmological health care.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:5

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Costs; Drug Prescriptions; Glaucoma; Humans; Latanoprost; Middle Aged; Miotics; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Quinoxalines; Retrospective Studies; Scotland; Sulfonamides; Sympathomimetics; Thiophenes; Trabeculectomy

2002
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2002, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Capecitabine; Carbamates; Ceftriaxone; Clonidine; Deoxycytidine; Diagnosis, Differential; Drug Eruptions; Ethacridine; Female; Fluorouracil; Humans; Immunosuppressive Agents; Indapamide; Isotretinoin; Isoxazoles; Leflunomide; Male; Middle Aged; Nelfinavir; Phenylcarbamates; Rivastigmine; Salicylates; Severity of Illness Index; Sulfonamides; Thiophenes

2002
Effect of Xalatan(R) and Cosopt(R) on the vascular tone of quiescent isolated pig ciliary arteries.
    Klinische Monatsblatter fur Augenheilkunde, 2002, Volume: 219, Issue:4

    Topics: Animals; Antihypertensive Agents; Ciliary Arteries; Culture Techniques; Dose-Response Relationship, Drug; Drug Combinations; Intraocular Pressure; Latanoprost; Potassium Chloride; Prostaglandins F, Synthetic; Sulfonamides; Swine; Thiophenes; Timolol; Vasoconstriction

2002
Additive intraocular pressure lowering effect of various medications with latanoprost.
    American journal of ophthalmology, 2002, Volume: 133, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Synergism; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes

2002
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:6

    Topics: Administration, Topical; Amiloride; Animals; Antihypertensive Agents; Aqueous Humor; Bumetanide; Diuretics; Electrophysiology; Female; Intraocular Pressure; Male; Mice; Sodium-Hydrogen Exchangers; Sulfonamides; Thiophenes

2002
[Weill-Marchesani syndrome. Late athalamia following antiglaucomatous surgery].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:7

    Topics: Abnormalities, Multiple; Adult; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Dwarfism; Female; Fingers; Glaucoma, Angle-Closure; Hand Deformities, Congenital; Humans; Intraocular Pressure; Iridectomy; Lens Implantation, Intraocular; Lens, Crystalline; Mitomycins; Phacoemulsification; Postoperative Complications; Sulfonamides; Syndrome; Thiophenes; Trabeculectomy; Vitrectomy

2002
Inhibition of carbonic anhydrase activity in cultured bovine corneal endothelial cells by dorzolamide.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:10

    Topics: Animals; Bicarbonates; Carbonates; Carbonic Anhydrase Inhibitors; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Corneal; Female; Hydrogen-Ion Concentration; Isotonic Solutions; Osmolar Concentration; Ringer's Solution; Sulfonamides; Thiophenes

2002
The pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary study.
    Acta ophthalmologica Scandinavica. Supplement, 2002, Volume: 236

    Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol

2002
Choroidal detachment induced by dorzolamide 20 years after cataract surgery.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:12

    Topics: Aged; Antihypertensive Agents; Cataract Extraction; Choroid Diseases; Drug Therapy, Combination; Female; Humans; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol

2002
Primary glaucoma in Burmese cats.
    Australian veterinary journal, 2002, Volume: 80, Issue:11

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Breeding; Cat Diseases; Cats; Female; Glaucoma; Latanoprost; Ophthalmic Solutions; Prednisolone; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol

2002
Functional analysis of retinal vessel diameter reaction to artificially raised intraocular pressure in glaucoma patients with and without dorzolamide therapy.
    VASA. Zeitschrift fur Gefasskrankheiten, 2002, Volume: 31, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Retinal Vessels; Sulfonamides; Thiophenes; Vascular Resistance

2002
Blockers of carbonic anhydrase can cause increase of retinal capillary diameter, decrease of extracellular and increase of intracellular pH in rat retinal organ culture.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2003, Volume: 241, Issue:2

    Topics: Acetazolamide; Actins; Animals; Capillaries; Carbonic Anhydrase Inhibitors; Extracellular Space; Female; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Male; Muscle, Smooth, Vascular; Organ Culture Techniques; Pericytes; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Vasodilation

2003
[Glaucoma: an ocular blood flow disorder?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2003, Volume: 100, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Rheology; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Timolol

2003
Experience with COSOPT, the fixed combination of timolol and dorzolamide, gained in Swiss ophthalmologists' offices.
    Current medical research and opinion, 2003, Volume: 19, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Physicians' Offices; Practice Patterns, Physicians'; Prostaglandins F, Synthetic; Sulfonamides; Switzerland; Thiophenes; Timolol; Treatment Outcome

2003
Effects of twice daily application of 2% dorzolamide on intraocular pressure in normal cats.
    Veterinary ophthalmology, 2003, Volume: 6, Issue:2

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cats; Female; Intraocular Pressure; Male; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiophenes; Tonometry, Ocular

2003
Comparison of the efficacy of the fixed-combination timolol/dorzolamide versus concomitant administration of timolol and dorzolamide.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2003
Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:3

    Topics: Animals; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Calcium; Carteolol; Cell Death; Dose-Response Relationship, Drug; Epinephrine; Glaucoma; Glutamic Acid; Latanoprost; Mice; Neuroblastoma; Neurons; Neuroprotective Agents; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol; Tumor Cells, Cultured

2003
The free amino acids and the aqueous humor pH after antiglaucomatics in vitro.
    Bratislavske lekarske listy, 2003, Volume: 104, Issue:1

    Topics: Aged; Aged, 80 and over; Amino Acids; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Male; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol

2003
Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzolamide, in Swiss ophthalmologists' offices.
    Current medical research and opinion, 2003, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cluster Analysis; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Ophthalmology; Sulfonamides; Switzerland; Thiophenes; Timolol

2003
Topical dorzolamide and metabolic acidosis in a neonate.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:8

    Topics: Acidosis; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Humans; Infant, Newborn; Male; Sulfonamides; Thiophenes

2003
Rapid and sensitive HPLC method for the simultaneous determination of dorzolamide hydrochloride and timolol maleate in eye drops with diode-array and UV detection.
    Die Pharmazie, 2003, Volume: 58, Issue:7

    Topics: Adrenergic beta-Antagonists; Calibration; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Indicators and Reagents; Ophthalmic Solutions; Reproducibility of Results; Spectrophotometry, Ultraviolet; Sulfonamides; Thiophenes; Timolol

2003
Patient persistency with pharmacotherapy in the management of glaucoma.
    European journal of ophthalmology, 2003, Volume: 13 Suppl 4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cohort Studies; Drug Utilization; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Patient Compliance; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes

2003
Switching from systemic to the topical carbonic anhydrase inhibitor dorzolamide: effect on the quality of life of glaucoma patients with drug-related side effects.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:4

    Topics: Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Glaucoma, Open-Angle; Health Status Indicators; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quality of Life; Sulfonamides; Thiophenes

2003
[Effects of ocular hypotensive agents on the circadian rhythm in intraocular pressure in rabbits as measured by telemetry].
    Nippon Ganka Gakkai zasshi, 2003, Volume: 107, Issue:9

    Topics: Animals; Circadian Rhythm; Intraocular Pressure; Male; Quinazolines; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol

2003
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.
    Bioorganic & medicinal chemistry letters, 2003, Sep-01, Volume: 13, Issue:17

    Topics: Administration, Topical; Animals; Benzolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Esters; Glaucoma; Humans; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes

2003
Prescription of topical antiglaucoma agents for patients with contraindications to beta-blockers.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2003, Volume: 38, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Contraindications; Databases, Factual; Drug Prescriptions; Female; Glaucoma; Humans; Latanoprost; Male; Middle Aged; National Health Programs; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quebec; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes; Timolol

2003
Ocular factors relevant to anti-glaucomatous eyedrop-related keratoepitheliopathy.
    Journal of glaucoma, 2003, Volume: 12, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carteolol; Dinoprost; Drug Therapy, Combination; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Keratitis; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Risk Factors; Sulfonamides; Tears; Thiophenes; Timolol

2003
Voltammetric and HPLC determination of dorzolamide hydrochloride in eye drops.
    Die Pharmazie, 2003, Volume: 58, Issue:12

    Topics: Buffers; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Indicators and Reagents; Ophthalmic Solutions; Potentiometry; Reproducibility of Results; Sulfonamides; Thiophenes

2003
Dorzolamide induces vasodilatation in isolated pre-contracted bovine retinal arteries.
    Experimental eye research, 2004, Volume: 78, Issue:2

    Topics: Animals; Carbonic Anhydrase Inhibitors; Cattle; Culture Techniques; Dose-Response Relationship, Drug; Retina; Retinal Artery; Sulfonamides; Thiophenes; Vasoconstriction; Vasodilation; Vasodilator Agents

2004
Optic nerve oxygen tension: the effects of timolol and dorzolamide.
    The British journal of ophthalmology, 2004, Volume: 88, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Drug Interactions; Heart Rate; Intraocular Pressure; Optic Disk; Oxygen; Partial Pressure; Sulfonamides; Swine; Thiophenes; Timolol

2004
Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:3

    Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Pulsatile Flow; Regional Blood Flow; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Fields

2004
Effects of dorzolamide hydrochloride on ocular tissues.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2004, Volume: 20, Issue:1

    Topics: Animals; Blotting, Western; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chromatography, High Pressure Liquid; Eye; Female; Immunohistochemistry; Instillation, Drug; Ophthalmic Solutions; Rabbits; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Tissue Distribution

2004
[Effect of various anti-glaucoma eyedrops on human corneal epithelial cells].
    Nippon Ganka Gakkai zasshi, 2004, Volume: 108, Issue:2

    Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cell Division; Dinoprost; Epithelium, Corneal; Glaucoma; Growth Inhibitors; Humans; Ophthalmic Solutions; Sulfonamides; Thiophenes

2004
Lichenoid drug eruption secondary to topical timolol and dorzolamide eye-drops.
    The Australasian journal of dermatology, 2004, Volume: 45, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Drug Eruptions; Glaucoma; Humans; Leg Dermatoses; Lichenoid Eruptions; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

2004
Studies on the mechanism of action of timolol and on the effects of suppression and redirection of aqueous flow on outflow facility.
    Experimental eye research, 2004, Volume: 78, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aqueous Humor; Ascorbic Acid; Carbonic Anhydrase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibronectins; Macaca fascicularis; Macaca mulatta; Sulfonamides; Thiophenes; Timolol

2004
Trends in glaucoma surgery before and after the introduction of new topical glaucoma pharmacotherapies.
    Journal of glaucoma, 2004, Volume: 13, Issue:3

    Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy; Drug Utilization; Filtering Surgery; Glaucoma, Open-Angle; Humans; Inpatients; Latanoprost; Medicare; Ophthalmic Solutions; Outpatients; Prevalence; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; United States

2004
[Intraocular pressure in rabbits after administration of 10% L-arginine HCl in 2% Trusopt].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2004, Volume: 60, Issue:2

    Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Pupil; Rabbits; Sulfonamides; Thiophenes

2004
Accelerated idioventricular rhythm associated to ophthalmic timolol/dorzolamide solution.
    International journal of cardiology, 2004, Volume: 95, Issue:2-3

    Topics: Accelerated Idioventricular Rhythm; Antihypertensive Agents; Drug Combinations; Electrocardiography; Female; Glaucoma, Open-Angle; Humans; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

2004
Endothelial changes associated with topical dorzolamide do appear to be significant.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:7

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Corneal Diseases; Endothelium, Corneal; Humans; Sulfonamides; Thiophenes

2004
Alphagan allergy may increase the propensity for multiple eye-drop allergy.
    Eye (London, England), 2005, Volume: 19, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cross Reactions; Drug Administration Schedule; Drug Hypersensitivity; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Longitudinal Studies; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes; Timolol

2005
An unusual appearance of limbal conjunctival follicles in a patient on brimonidine and dorzolamide.
    Eye (London, England), 2005, Volume: 19, Issue:3

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Conjunctival Diseases; Glaucoma, Open-Angle; Humans; Male; Quinoxalines; Sulfonamides; Thiophenes

2005
Dorzolamide-induced choroidal detachment in a surgically untreated eye.
    American journal of ophthalmology, 2004, Volume: 138, Issue:2

    Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Choroid Diseases; Female; Glaucoma, Open-Angle; Humans; Sulfonamides; Thiophenes; Ultrasonography

2004
[Comparison of the effectiveness of a mixture of 10% L-arginine and HCl combined with 0.5% Timoptol and with 2% Trusopt: and the individual components on intraocular pressure in an experiment on rabbits].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2004, Volume: 60, Issue:3

    Topics: Animals; Antihypertensive Agents; Arginine; Carbonic Anhydrase Inhibitors; Drug Combinations; Intraocular Pressure; Male; Rabbits; Sulfonamides; Thiophenes; Timolol

2004
[Neuroprotection and vasoprotection in glaucoma].
    Oftalmologia (Bucharest, Romania : 1990), 2004, Volume: 48, Issue:2

    Topics: Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Carteolol; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Neuroprotective Agents; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome

2004
The effect of carbonic anhydrase inhibition on leptin secretion by rat adipose tissue.
    Journal of enzyme inhibition and medicinal chemistry, 2004, Volume: 19, Issue:2

    Topics: Adipose Tissue; Animals; Carbonic Anhydrase III; Dexamethasone; Enzyme Inhibitors; Epididymis; Insulin; Leptin; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes

2004
Influence of inorganic mobile phase additives on the retention, efficiency and peak symmetry of protonated basic compounds in reversed-phase liquid chromatography.
    Journal of chromatography. A, 2004, Sep-17, Volume: 1049, Issue:1-2

    Topics: Algorithms; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Indicators and Reagents; Inorganic Chemicals; Labetalol; Ophthalmic Solutions; Sulfonamides; Thiophenes

2004
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Jan-20, Volume: 102, Issue:1

    Topics: Administration, Topical; Animals; Chemistry, Pharmaceutical; Cyclodextrins; Eye; Rabbits; Sulfonamides; Thiophenes

2005
Contact dermatitis caused by allergy to dorzolamide.
    Contact dermatitis, 2005, Volume: 52, Issue:2

    Topics: Aged; Dermatitis, Allergic Contact; Diagnosis, Differential; Glaucoma, Open-Angle; Humans; Male; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes

2005
Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2005, Volume: 243, Issue:2

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Injections, Intravenous; Ion-Selective Electrodes; Optic Nerve; Oxygen; Partial Pressure; Polarography; Retina; Retinal Vessels; Sulfonamides; Swine; Thiophenes; Vasodilation

2005
Topically administered timolol and dorzolamide reduce intraocular pressure and protect retinal ganglion cells in a rat experimental glaucoma model.
    The British journal of ophthalmology, 2005, Volume: 89, Issue:4

    Topics: Animals; Antihypertensive Agents; Cell Count; Cell Survival; Cytoprotection; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Timolol

2005
Volumetric colour Doppler imaging: a useful tool for the determination of ocular blood flow in glaucoma patients?
    Eye (London, England), 2006, Volume: 20, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Flow Velocity; Glaucoma; Humans; Middle Aged; Observer Variation; Ophthalmic Artery; Regional Blood Flow; Reproducibility of Results; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color

2006
European Glaucoma Prevention Study.
    Ophthalmology, 2005, Volume: 112, Issue:9

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes

2005
Toxic epidermal necrolysis secondary to timolol, dorzolamide, and latanoprost eyedrops.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:5

    Topics: Antihypertensive Agents; Female; Glaucoma; Humans; Latanoprost; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Stevens-Johnson Syndrome; Sulfonamides; Thiophenes; Timolol

2005
The in vitro effects of some pesticides on carbonic anhydrase activity of Oncorhynchus mykiss and Cyprinus carpio carpio fish.
    Journal of hazardous materials, 2006, May-20, Volume: 132, Issue:2-3

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Carps; Diazinon; In Vitro Techniques; Insecticides; Nitriles; Oncorhynchus mykiss; Pyrethrins; Sulfonamides; Thiazines; Thiophenes; Water Pollutants, Chemical

2006
Dorzolamide and timolol saves retinal ganglion cells in glaucomatous adult rats.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:6

    Topics: Animals; Antihypertensive Agents; Cell Count; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Pilot Projects; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Time Factors; Timolol

2005
Effect of topical dorzolamide on rabbit central corneal thickness.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2006, Volume: 39, Issue:2

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cornea; Male; Rabbits; Random Allocation; Sulfonamides; Thiophenes; Ultrasonography

2006
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:3

    Topics: Animals; Annexin A5; Apoptosis; Carbonic Anhydrase Inhibitors; Caspase 3; Caspases; Cell Culture Techniques; Cell Survival; Flow Cytometry; Glyoxal; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Situ Nick-End Labeling; Lysine; Neurons; Neuroprotective Agents; Pyruvaldehyde; Rats; Reactive Oxygen Species; Retina; Sulfonamides; Thiophenes

2006
Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells.
    The Kaohsiung journal of medical sciences, 2006, Volume: 22, Issue:2

    Topics: Animals; Antihypertensive Agents; Betaxolol; Calcium; Endothelium, Corneal; Glaucoma; Levobunolol; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Timolol

2006
Allergic contact dermatitis from timolol and dorzolamide eye drops.
    Contact dermatitis, 2006, Volume: 54, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dermatitis, Allergic Contact; Epinephrine; Female; Glaucoma; Humans; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes; Timolol

2006
Effects of topical antiglaucoma application on conjunctival impression cytology specimens.
    American journal of ophthalmology, 2006, Volume: 142, Issue:1

    Topics: Administration, Topical; Antihypertensive Agents; Conjunctiva; Cross-Sectional Studies; Drug Therapy, Combination; Epithelium; Glaucoma, Open-Angle; Humans; Latanoprost; Metaplasia; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2006
[Intraocular pressure after ND: YAG laser capsulotomy in pseudophakic patients with glaucoma].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2006, Volume: 60, Issue:2

    Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cataract Extraction; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Preoperative Care; Pseudophakia; Quinoxalines; Sulfonamides; Thiophenes

2006
Optic nerve pH and PO2: the effects of carbonic anhydrase inhibition, and metabolic and respiratory acidosis.
    Acta ophthalmologica Scandinavica, 2006, Volume: 84, Issue:4

    Topics: Acidosis, Respiratory; Ammonium Chloride; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Optic Disk; Optic Nerve; Oxygen; Oxygen Consumption; Partial Pressure; Polarography; Sulfonamides; Swine; Thiophenes

2006
Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:1

    Topics: Administration, Topical; Aged; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Carteolol; Case-Control Studies; Chemokines; Cloprostenol; Cytokines; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Tears; Thiophenes; Timolol

2007
Use of dorzolamide for patients with X-linked retinoschisis.
    Retina (Philadelphia, Pa.), 2006, Volume: 26, Issue:7

    Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Cysts; Fovea Centralis; Humans; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2006
Effect of 2% dorzolamide on retinal blood flow: a study on juvenile primary open-angle glaucoma patients already receiving 0.5% timolol.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol

2007
Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa.
    American journal of ophthalmology, 2006, Volume: 142, Issue:4

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Humans; Macular Edema; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2006
Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.
    Drugs & aging, 2006, Volume: 23, Issue:9

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2006
[Blurred vision after instillation of topical carbonic anhydrase inhibitor].
    Nippon Ganka Gakkai zasshi, 2006, Volume: 110, Issue:9

    Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Male; Middle Aged; Sulfonamides; Tears; Thiazines; Thiophenes; Time Factors; Visual Acuity

2006
The additive effect of topical dorzolamide and systemic acetazolamide in pediatric glaucoma.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2006, Volume: 10, Issue:5

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular

2006
Drug-induced ectropion: what is best practice?
    Ophthalmology, 2007, Volume: 114, Issue:2

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Ectropion; Eyelids; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes

2007
Dorzolamide hydrochloride: an antiglaucoma agent.
    Acta crystallographica. Section C, Crystal structure communications, 2007, Volume: 63, Issue:Pt 2

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Crystallization; Crystallography, X-Ray; Glaucoma; Humans; Molecular Conformation; Sulfonamides; Thiophenes

2007
Anosmia as an adverse effect of dorzolamid.
    Acta ophthalmologica Scandinavica, 2007, Volume: 85, Issue:2

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Olfaction Disorders; Sulfonamides; Thiophenes

2007
[Case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy].
    Nippon Ganka Gakkai zasshi, 2007, Volume: 111, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Argon; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Ophthalmic Solutions; Quinazolines; Sulfonamides; Thiophenes; Trabeculectomy; Treatment Outcome

2007
Acute visual loss due to serous retinal detachment from acquired optic pit may be a rare presentation of primary open-angle glaucoma.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Acute Disease; Antihypertensive Agents; Diclofenac; Drug Therapy, Combination; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Middle Aged; Optic Disk; Optic Nerve Diseases; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Vision Disorders; Visual Acuity

2007
Hypotony and choroidal detachment as a complication of topical combined timolol and dorzolamide.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract Extraction; Choroid Diseases; Chronic Disease; Drug Interactions; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Trabeculectomy

2007
[Toxic epidermal necrolysis following eyedrop treatment for glaucoma].
    Annales de dermatologie et de venereologie, 2007, Volume: 134, Issue:4 Pt 1

    Topics: Conjunctivitis; Female; Genital Diseases, Female; Glaucoma; Humans; Middle Aged; Ophthalmic Solutions; Stevens-Johnson Syndrome; Sulfonamides; Thiophenes

2007
Hypotensive effect of profilin on rabbit intraocular pressure.
    European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2

    Topics: Animals; Antihypertensive Agents; Intraocular Pressure; Latanoprost; Pilocarpine; Profilins; Prostaglandins F, Synthetic; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; Sulfonamides; Thiophenes

2007
Diuretics, placebos, and the European glaucoma prevention study.
    American journal of ophthalmology, 2007, Volume: 144, Issue:2

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Diuretics; Europe; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Prevalence; Randomized Controlled Trials as Topic; Retinal Hemorrhage; Risk Factors; Sulfonamides; Thiophenes

2007
Variable involvement of the perivascular retinal tissue in carbonic anhydrase inhibitor induced relaxation of porcine retinal arterioles in vitro.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:10

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetazolamide; Animals; Arterioles; Carbonic Anhydrase Inhibitors; Muscle, Smooth, Vascular; Myography; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasoconstrictor Agents; Vasodilation

2007
Costs and effectiveness of travoprost versus a dorzolamide + timolol fixed combination in first-line treatment of glaucoma: analysis conducted on the United Kingdom General Practitioner Research Database.
    Current medical research and opinion, 2007, Volume: 23, Issue:12

    Topics: Aged; Antihypertensive Agents; Cloprostenol; Cost-Benefit Analysis; Databases, Factual; Drug Combinations; Drug Costs; Female; Glaucoma; Humans; Male; Physicians, Family; Sulfonamides; Thiophenes; Timolol; Travoprost; United Kingdom

2007
Carbonic anhydrases IV and IX: subcellular localization and functional role in mouse skeletal muscle.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:2

    Topics: Animals; Carbonic Anhydrase IV; Carbonic Anhydrase IX; Carbonic Anhydrases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Mice; Mice, Knockout; Microscopy, Confocal; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Sarcolemma; Sarcoplasmic Reticulum; Sulfonamides; Thiophenes; Time Factors; Transport Vesicles

2008
[Acute closed-angle glaucoma after gynecological surgery under general anesthesia].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:9

    Topics: Acetazolamide; Acute Disease; Anesthesia, General; Atropine; Combined Modality Therapy; Corneal Edema; Dexamethasone; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Humans; Laser Therapy; Mannitol; Middle Aged; Mydriasis; Pilocarpine; Postoperative Complications; Sulfonamides; Thiophenes; Timolol; Vomiting

2007
Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study.
    American journal of ophthalmology, 2008, Volume: 145, Issue:1

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Prevalence; Risk Factors; Sulfonamides; Thiophenes; Treatment Outcome

2008
Adoption of new antiglaucoma drugs in Finland: impact of changes in copayment.
    Clinical therapeutics, 2007, Volume: 29, Issue:11

    Topics: Carbonic Anhydrase Inhibitors; Data Collection; Data Interpretation, Statistical; Drug Utilization; Finland; Glaucoma; Humans; Insurance, Health, Reimbursement; Latanoprost; Models, Statistical; Prostaglandins; Prostaglandins F, Synthetic; Regression Analysis; Sulfonamides; Thiophenes

2007
Drug modification of angiogenesis in a rat cornea model.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:1

    Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Corneal Neovascularization; Corneal Stroma; Disease Models, Animal; Drug Implants; Fibroblast Growth Factor 2; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Timolol

2008
Systemic contact dermatitis to dorzolamide eye drops.
    Contact dermatitis, 2008, Volume: 58, Issue:3

    Topics: Aged; Aged, 80 and over; Allergens; Dermatitis, Allergic Contact; Dermatitis, Perioral; Diagnosis, Differential; Female; Humans; Ophthalmic Solutions; Patch Tests; Sulfonamides; Thiophenes

2008
Chronic kidney disease--a disease domain complex.
    Geriatrics, 2008, Volume: 63, Issue:3

    Topics: Aged; Alendronate; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Bone Density Conservation Agents; Calcium; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy; Female; Glomerular Filtration Rate; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; Kidney Failure, Chronic; Metoprolol; Nitroglycerin; Sulfonamides; Thiophenes

2008
Dorzolamide increases retinal oxygen tension after branch retinal vein occlusion.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:3

    Topics: Animals; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Fluorescein Angiography; Hypoxia; Injections, Intravenous; Ion-Selective Electrodes; Ischemia; Oxygen; Oxygen Consumption; Partial Pressure; Retina; Retinal Vein Occlusion; Sulfonamides; Swine; Thiophenes

2008
Erythema multiforme after use of topical dorzolamide.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:1

    Topics: Administration, Topical; Aged, 80 and over; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Cataract Extraction; Drug Eruptions; Erythema Multiforme; Female; Glaucoma; Humans; Hydrocortisone; Sulfonamides; Thiophenes; Visual Acuity

2008
[Comparative study of the effects of two anti-glaucomatous drugs on the corneal thickness in rabbits with corneal autografts].
    Archivos de la Sociedad Espanola de Oftalmologia, 2008, Volume: 83, Issue:4

    Topics: Animals; Antihypertensive Agents; Cornea; Corneal Transplantation; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes

2008
Estimation of ocular rigidity based on measurement of pulse amplitude using pneumotonometry and fundus pulse using laser interferometry in glaucoma.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:9

    Topics: Aged; Blood Pressure; Drug Therapy, Combination; Female; Fundus Oculi; Glaucoma, Open-Angle; Humans; Interferometry; Intraocular Pressure; Lasers; Latanoprost; Light; Male; Middle Aged; Prostaglandins F, Synthetic; Pulse; Reference Values; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2008
Additive effect of dorzolamide hydrochloride to patients taking travoprost: a retrospective study.
    Optometry (St. Louis, Mo.), 2008, Volume: 79, Issue:9

    Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Retrospective Studies; Sulfonamides; Thiophenes; Travoprost; Treatment Outcome; Visual Fields

2008
[Toxic epidermal necrolysis following dorzolamide eyedrops].
    Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1

    Topics: Aged; Critical Care; Drug Therapy, Combination; Eye Diseases; Female; Glaucoma, Open-Angle; Humans; Metronidazole; Ophthalmic Solutions; Pheniramine; Prednisolone; Stevens-Johnson Syndrome; Sulfonamides; Thiophenes

2008
The vasodilating effect of acetazolamide and dorzolamide involves mechanisms other than carbonic anhydrase inhibition.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetazolamide; Acidosis; Animals; Arterioles; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hypercapnia; Muscle, Smooth, Vascular; Myography; Nifedipine; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2009
[Intraocular pressure after instillation of amino acid arginine and combination of two antiglaucomatics (Trusopt + Xalatane mixture) in rabbits].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2008, Volume: 64, Issue:4

    Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes

2008
Relation of response to treatment with dorzolamide in X-linked retinoschisis to the mechanism of functional loss in retinoschisin.
    American journal of ophthalmology, 2009, Volume: 147, Issue:1

    Topics: Adult; Blotting, Western; Carbonic Anhydrase Inhibitors; Cysts; DNA Mutational Analysis; Eye Proteins; Gene Expression Regulation; Humans; Male; Mutagenesis, Site-Directed; Mutation, Missense; Ophthalmic Solutions; Polymerase Chain Reaction; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Young Adult

2009
Intraocular pressure lowering, change of antiapoptotic molecule expression, and neuroretinal changes by dorzolamide 2%/timolol 0.5% combination in a chronic ocular hypertension rat model.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:6

    Topics: Animals; bcl-X Protein; Cell Survival; Disease Models, Animal; Drug Combinations; Glial Fibrillary Acidic Protein; Intraocular Pressure; Male; Ocular Hypertension; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; RNA, Messenger; Sulfonamides; Thiophenes; Timolol

2008
Short-term effect of topical dorzolamide hydrochloride on intrastromal corneal pressure in rabbit corneas in vivo.
    Cornea, 2009, Volume: 28, Issue:2

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Corneal Stroma; Drug Administration Schedule; Male; Pressure; Rabbits; Sulfonamides; Thiophenes; Time Factors

2009
Effects of dorzolamide on choroidal blood flow, ciliary blood flow, and aqueous production in rabbits.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:5

    Topics: Administration, Topical; Animals; Aqueous Humor; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Choroid; Ciliary Body; Female; Fluorophotometry; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Rabbits; Regional Blood Flow; Sulfonamides; Thiophenes; Vasodilation

2009
Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Visual Fields

2009
Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:1

    Topics: Acrylates; Adhesives; Animals; Antihypertensive Agents; Biological Transport; Cornea; Dose-Response Relationship, Drug; Drug Compounding; Gels; In Vitro Techniques; Intraocular Pressure; Male; Mucous Membrane; Ophthalmic Solutions; Permeability; Rabbits; Sulfonamides; Terpenes; Thiophenes

2010
Nanoemulsion as a potential ophthalmic delivery system for dorzolamide hydrochloride.
    AAPS PharmSciTech, 2009, Volume: 10, Issue:3

    Topics: Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cornea; Drug Delivery Systems; Drug Stability; Emulsions; Eye Diseases; Glaucoma; Hydrogen-Ion Concentration; Irritants; Male; Nanoparticles; Ophthalmic Solutions; Osmolar Concentration; Particle Size; Rabbits; Rheology; Solubility; Sulfonamides; Surface Tension; Thiophenes; Viscosity

2009
Corneal thickness and glaucoma medications.
    Ophthalmology, 2009, Volume: 116, Issue:7

    Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cornea; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome

2009
Relative efficacy of prostaglandins.
    Ophthalmology, 2009, Volume: 116, Issue:7

    Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome

2009
Choroidal detachment in association with topical dorzolamide: is hypotony always the cause?
    Clinical & experimental ophthalmology, 2009, Volume: 37, Issue:7

    Topics: Aged; Antihypertensive Agents; Choroid Diseases; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Visual Acuity

2009
Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:6

    Topics: Acetazolamide; Animals; Aorta, Thoracic; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Sodium Nitrite; Sulfonamides; Thiophenes; Vasodilation

2009
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma.
    Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23

    Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Drug Discovery; Glaucoma, Open-Angle; Models, Molecular; Molecular Structure; Nitric Oxide; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiophenes

2009
Retinal arteriolar vascular reactivity in untreated and progressive primary open-angle glaucoma.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:4

    Topics: Administration, Topical; Aged; Arterioles; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Disease Progression; Glaucoma, Open-Angle; Humans; Hypercapnia; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Optic Disk; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes

2010
The effects of combination glaucoma medications on ocular surface epithelial cells.
    Advances in therapy, 2009, Volume: 26, Issue:10

    Topics: Antihypertensive Agents; Brimonidine Tartrate; Conjunctiva; Cornea; Drug Combinations; Epithelial Cells; Humans; In Vitro Techniques; Ophthalmic Solutions; Quinoxalines; Sodium Chloride; Sulfonamides; Thiophenes; Timolol

2009
Hyaluronic acid modified chitosan nanoparticles for effective management of glaucoma: development, characterization, and evaluation.
    Journal of drug targeting, 2010, Volume: 18, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Biological Availability; Carbonic Anhydrase Inhibitors; Chitosan; Drug Carriers; Glaucoma; Hyaluronic Acid; Nanoparticles; Rabbits; Sulfonamides; Thiophenes; Timolol

2010
Efficacy of sustained topical dorzolamide therapy for cystic macular lesions in patients with X-linked retinoschisis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Eye Proteins; Follow-Up Studies; Humans; Intraocular Pressure; Macular Edema; Middle Aged; Ophthalmic Solutions; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Young Adult

2010
Simultaneous quantification of carteolol and dorzolamide in rabbit aqueous humor and ciliary body by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Mar-15, Volume: 878, Issue:9-10

    Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carteolol; Chromatography, High Pressure Liquid; Ciliary Body; Disease Models, Animal; Humans; Male; Ocular Hypertension; Rabbits; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Thiophenes

2010
Use of rituximab for periocular and intraocular mucosa-associated lymphoid tissue lymphoma.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:2

    Topics: Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Brimonidine Tartrate; Drug Therapy, Combination; Eye Neoplasms; Female; Glaucoma; Humans; Latanoprost; Loteprednol Etabonate; Lymphoma, B-Cell, Marginal Zone; Middle Aged; Parotid Neoplasms; Prostaglandins F, Synthetic; Quinoxalines; Rituximab; Sulfonamides; Thiophenes; Timolol

2010
Diagnostic and therapeutic challenges.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:1

    Topics: Acetazolamide; Adult; Electroretinography; Fluorescein Angiography; Fundus Oculi; Humans; Macular Edema; Male; Ophthalmic Solutions; Sulfonamides; Tablets; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Visual Acuity; Visual Fields

2011
Development of dorzolamide hydrochloride in situ gel nanoemulsion for ocular delivery.
    Drug development and industrial pharmacy, 2010, Volume: 36, Issue:11

    Topics: Animals; Antihypertensive Agents; Biological Availability; Delayed-Action Preparations; Emulsions; Excipients; Eye; Gels; Male; Nanoparticles; Poloxamer; Rabbits; Sulfonamides; Surface-Active Agents; Thiophenes; Time Factors

2010
Chiral separation and quantitation of dorzolamide hydrochloride enantiomers by high-performance liquid chromatography.
    Journal of separation science, 2010, Volume: 33, Issue:15

    Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Molecular Conformation; Stereoisomerism; Sulfonamides; Temperature; Thiophenes

2010
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugs: formulation of dorzolamide eye drop microparticle suspension.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:2

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Delayed-Action Preparations; Drug Stability; Excipients; gamma-Cyclodextrins; Hydrogen-Ion Concentration; Hypromellose Derivatives; Methazolamide; Methylcellulose; Polymers; Rabbits; Solubility; Sulfonamides; Suspensions; Thiazines; Thiophenes; Time Factors; Tissue Distribution

2010
Predictors for visual field progression.
    Acta ophthalmologica, 2010, Volume: 88, Issue:5

    Topics: Antihypertensive Agents; Blood Flow Velocity; Disease Progression; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Optic Disk; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision Disorders; Visual Fields

2010
Efficacy of sustained topical dorzolamide therapy for cystic macular lesions in patients with retinitis pigmentosa and usher syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:9

    Topics: Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Follow-Up Studies; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Retina; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Usher Syndromes; Visual Acuity; Young Adult

2010
Efficacy of topical dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome.
    Documenta ophthalmologica. Advances in ophthalmology, 2010, Volume: 121, Issue:3

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Humans; Macular Edema; Male; Retinal Cone Photoreceptor Cells; Retinal Diseases; Sulfonamides; Syndrome; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Visual Field Tests; Young Adult

2010
Skin eruption and thrombocytopaenia in a woman with glaucoma: a case report.
    The West Indian medical journal, 2010, Volume: 59, Issue:1

    Topics: Anti-Infective Agents; Antihypertensive Agents; Biopsy; Dapsone; Drug Eruptions; Female; Glaucoma; Humans; Liver Function Tests; Middle Aged; Ophthalmic Solutions; Platelet Count; Sulfonamides; Thiophenes; Thrombocytopenia; Timolol

2010
The use of carbonic anhydrase inhibitors in the retreatment of cystic macular lesions in retinitis pigmentosa and X-linked retinoschisis.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:2

    Topics: Acetazolamide; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Retinitis Pigmentosa; Retinoschisis; Retreatment; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Usher Syndromes; Visual Acuity

2011
Electrophysiological consequences of experimental branch retinal vein occlusion in pigs and the effect of dorzolamide.
    Investigative ophthalmology & visual science, 2011, Feb-16, Volume: 52, Issue:2

    Topics: Animals; Carbonic Anhydrase Inhibitors; Electroretinography; Female; Fluorescein Angiography; Ophthalmoscopy; Photography; Reperfusion Injury; Retina; Retinal Vein Occlusion; Retinal Vessels; Sulfonamides; Swine; Thiophenes

2011
The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.
    Journal of glaucoma, 2011, Volume: 20, Issue:1

    Topics: Adult; Antihypertensive Agents; Blindness; Brimonidine Tartrate; Decision Trees; Disease Progression; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Biological; Monte Carlo Method; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol

2011
Ability of dorzolamide hydrochloride and timolol maleate to target mitochondria in glaucoma therapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2011, Volume: 129, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Autoradiography; Cell Line; Chromatography, Thin Layer; Deoxyguanosine; DNA Fragmentation; Glaucoma, Open-Angle; Humans; Hydrogen Peroxide; Mitochondria; Oxidative Stress; Sulfonamides; Thiophenes; Timolol; Tissue Donors; Trabecular Meshwork

2011
A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug.
    Biomedical materials (Bristol, England), 2011, Volume: 6, Issue:2

    Topics: Animals; Antihypertensive Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Cornea; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Glaucoma; Polyesters; Polymers; Porosity; Rabbits; Regression Analysis; Sulfonamides; Tetrazolium Salts; Thiazoles; Thiophenes; X-Ray Diffraction

2011
[Comparison of primary medicament therapy effects and primary argon laser trabeculoplasty on regulation of intraocular pressure and stability of perimetry findings in open angle glaucoma].
    Vojnosanitetski pregled, 2011, Volume: 68, Issue:3

    Topics: Aged; Antihypertensive Agents; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Lasers, Gas; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Visual Field Tests

2011
X-linked retinoschisis maculopathy treated with topical dorzolamide, and relationship to genotype.
    Eye (London, England), 2011, Volume: 25, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Child; Eye Proteins; Female; Genetic Diseases, X-Linked; Genotype; Humans; Macula Lutea; Male; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity; Young Adult

2011
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.
    Bioorganic & medicinal chemistry letters, 2011, Jun-01, Volume: 21, Issue:11

    Topics: Animals; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Disease Models, Animal; Glaucoma; Humans; Models, Molecular; Molecular Structure; Nitric Oxide; Ocular Hypertension; Protein Isoforms; Rabbits; Sulfonamides; Thiophenes

2011
In vitro and in vivo evaluation of an intraocular implant for glaucoma treatment.
    International journal of pharmaceutics, 2011, Aug-30, Volume: 415, Issue:1-2

    Topics: Animals; Antihypertensive Agents; Calorimetry, Differential Scanning; Drug Carriers; Drug Implants; Eye; Glaucoma; Intraocular Pressure; Kinetics; Microscopy, Electron, Scanning; Polyesters; Polyethylene Glycols; Propylene Glycols; Rabbits; Solubility; Sulfonamides; Surface Properties; Thiophenes

2011
Ocular pharmacokinetics of dorzolamide and brinzolamide after single and multiple topical dosing: implications for effects on ocular blood flow.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:9

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Chromatography, Liquid; Drug Administration Schedule; Eye; Male; Optic Nerve; Rabbits; Regional Blood Flow; Sulfonamides; Tandem Mass Spectrometry; Thiazines; Thiophenes

2011
A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology.
    Journal of enzyme inhibition and medicinal chemistry, 2012, Volume: 27, Issue:1

    Topics: Acrylic Resins; Animals; Carbonic Anhydrases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glaucoma; Isosorbide Dinitrate; Male; Molecular Structure; Nitrates; Nitric Oxide; Rabbits; Sulfonamides; Thiophenes; Time Factors

2012
Topical dorzolamide for treatment of cystoid macular edema in patients with choroideremia.
    Retina (Philadelphia, Pa.), 2012, Volume: 32, Issue:4

    Topics: Carbonic Anhydrase Inhibitors; Choroideremia; Contrast Sensitivity; Humans; Macular Edema; Male; Middle Aged; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Visual Field Tests

2012
The effect of dorzolamide 2% on circadian intraocular pressure in cats with primary congenital glaucoma.
    Veterinary ophthalmology, 2011, Volume: 14 Suppl 1

    Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Cat Diseases; Cats; Circadian Rhythm; Female; Glaucoma; Intraocular Pressure; Male; Sulfonamides; Thiophenes

2011
The clinical efficacy of a topical dorzolamide in the management of cystoid macular edema in patients with retinitis pigmentosa.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2012, Volume: 250, Issue:6

    Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Retina; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Visual Field Tests; Visual Fields; Young Adult

2012
The long-term outcomes of four alternative treatment strategies for primary open-angle glaucoma.
    Acta ophthalmologica, 2012, Volume: 90, Issue:1

    Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cost-Benefit Analysis; Decision Support Techniques; Disease Progression; Drug Costs; Economics, Pharmaceutical; Follow-Up Studies; Glaucoma, Open-Angle; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quality-Adjusted Life Years; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2012
The effects of a fixed combination of 0.5% timolol and 1% dorzolamide on optic nerve head blood circulation.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Synergism; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Optic Disk; Perfusion; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Young Adult

2012
A novel and rapid validated stability-indicating UPLC method of related substances for dorzolamide hydrochloride and timolol maleate in ophthalmic dosage form.
    Journal of chromatographic science, 2012, Volume: 50, Issue:9

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Contamination; Drug Stability; Hydrogen-Ion Concentration; Linear Models; Models, Molecular; Ophthalmic Solutions; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Thiophenes; Timolol

2012
Retrobulbar hemodynamics before and after oculopression with and without dorzolamide.
    Current eye research, 2012, Volume: 37, Issue:8

    Topics: Administration, Topical; Aged; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Tonometry, Ocular; Ultrasonography, Doppler, Color

2012
In vivo imaging reveals novel aspects of retinal disease progression in Rs1h(-/Y) mice but no therapeutic effect of carbonic anhydrase inhibition.
    Veterinary ophthalmology, 2012, Volume: 15 Suppl 2

    Topics: Animals; Carbonic Anhydrase Inhibitors; Cell Adhesion Molecules; Eye Proteins; Gene Deletion; Gene Expression Regulation; Male; Mice; Ophthalmic Solutions; Retina; Retinoschisis; Sulfonamides; Thiophenes

2012
Effects of ocular administration of ophthalmic 2% dorzolamide hydrochloride solution on aqueous humor flow rate and intraocular pressure in clinically normal cats.
    American journal of veterinary research, 2012, Volume: 73, Issue:7

    Topics: Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cats; Female; Fluorophotometry; Intraocular Pressure; Linear Models; Male; Ophthalmic Solutions; Random Allocation; Sulfonamides; Thiophenes; Tonometry, Ocular

2012
Regulation of retinal proteome by topical antiglaucomatous eye drops in an inherited glaucoma rat model.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Calmodulin; Carbonic Anhydrase II; Cloprostenol; Disease Models, Animal; Glaucoma; HMGB1 Protein; HSP70 Heat-Shock Proteins; Intraocular Pressure; Ophthalmic Solutions; Peptide Mapping; Proteome; Proteomics; Rats; Retina; Sulfonamides; Thiophenes; Travoprost

2012
Dorzolamide-induced relaxation of intraocular porcine ciliary arteries in vitro depends on nitric oxide and the vascular endothelium.
    Current eye research, 2012, Volume: 37, Issue:12

    Topics: Acetazolamide; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isometric Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxadiazoles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Sulfonamides; Swine; Thiazines; Thiophenes; Vasodilation; Vasodilator Agents

2012
[The rabbit's IOP values after instillation of the L-arginine HCL with selected antiglaucomatic drugs mixtures prepared in vitro. (comparative study of results of the experimental works)].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2012, Volume: 68, Issue:2

    Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol

2012
Topical dorzolamide therapy for taxane-related macular oedema.
    Eye (London, England), 2013, Volume: 27, Issue:1

    Topics: Administration, Topical; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Female; Humans; Macular Edema; Middle Aged; Paclitaxel; Sulfonamides; Thiophenes; Treatment Outcome

2013
Topical dorzolamide treatment of macular cysts in the enhanced S-cone syndrome patient.
    Documenta ophthalmologica. Advances in ophthalmology, 2013, Volume: 126, Issue:3

    Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Cysts; Electroretinography; Eye Diseases, Hereditary; Follow-Up Studies; Humans; Macular Edema; Male; Ophthalmic Solutions; Retinal Degeneration; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Visual Acuity

2013
Preparation of a molecularly imprinted soft contact lens as a new ocular drug delivery system for dorzolamide.
    Current drug delivery, 2013, Volume: 10, Issue:3

    Topics: Administration, Ophthalmic; Adsorption; Carbonic Anhydrase Inhibitors; Contact Lenses, Hydrophilic; Drug Delivery Systems; Hydrogels; Methacrylates; Molecular Imprinting; Sulfonamides; Thiophenes

2013
Congenital glaucoma with acquired peripheral circumferential iris degeneration.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2013, Volume: 17, Issue:1

    Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Drug Therapy, Combination; Eye Abnormalities; Female; Forkhead Transcription Factors; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Iris; Point Mutation; Sequence Deletion; Sulfonamides; Thiophenes; Timolol

2013
Evaluation of adverse events in self-reported sulfa-allergic patients using topical carbonic anhydrase inhibitors.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:5

    Topics: Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cohort Studies; Drug Hypersensitivity; Female; Glaucoma; Humans; Male; Middle Aged; Prostaglandins; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes

2013
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
    Seminars in ophthalmology, 2013, Volume: 28, Issue:2

    Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A

2013
Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide.
    Ophthalmic genetics, 2014, Volume: 35, Issue:2

    Topics: Adult; Carbonic Anhydrase Inhibitors; Cysts; Electroretinography; Eye Proteins; Humans; Male; Mutation, Missense; Polymerase Chain Reaction; Retinal Diseases; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence

2014
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
    Investigative ophthalmology & visual science, 2013, Jun-21, Volume: 54, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular

2013
Therapeutic effect of prolonged treatment with topical dorzolamide for cystoid macular oedema in patients with retinitis pigmentosa.
    The British journal of ophthalmology, 2013, Volume: 97, Issue:9

    Topics: Administration, Topical; Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Middle Aged; Prospective Studies; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Time Factors; Tomography, Optical Coherence; Young Adult

2013
[Contribution focused to clarify correlation between mixtures of the free amino acids with antiglaucomatics in influencing the IOP in rabbits after application into the conjunctival sac].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2013, Volume: 69, Issue:1

    Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol

2013
A decrease of the rabbit's physiologic IOP after the application of specific amino acids and double combination of antiglaucomatics mixture.
    Bratislavske lekarske listy, 2013, Volume: 114, Issue:7

    Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Taurine; Thiophenes; Timolol

2013
Efficacy of prophylactic antiglaucoma and anti-inflammatory medications in canine primary angle-closure glaucoma: a multicenter retrospective study (2004-2012).
    Veterinary ophthalmology, 2014, Volume: 17, Issue:3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Quaternary Ammonium Compounds; Retrospective Studies; Sulfonamides; Thiophenes

2014
Sarcoidosis patient: an unexpected reaction to carbonic anhydrase enzyme inhibitor.
    BMJ case reports, 2013, Jul-26, Volume: 2013

    Topics: Carbonic Anhydrase Inhibitors; Eye Diseases; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Sarcoidosis; Sulfonamides; Thiophenes

2013
Design and in vitro characterization of small unilamellar niosomes as ophthalmic carrier of dorzolamide hydrochloride.
    Pharmaceutical development and technology, 2014, Volume: 19, Issue:6

    Topics: Chemistry, Pharmaceutical; Cholesterol; Drug Carriers; Drug Delivery Systems; Hexoses; Liposomes; Ophthalmic Solutions; Organophosphates; Particle Size; Polyethylene Glycols; Sulfonamides; Surface-Active Agents; Thiophenes

2014
Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
    Bioorganic & medicinal chemistry, 2013, Nov-15, Volume: 21, Issue:22

    Topics: Antigens, Neoplasm; Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Crystallography, X-Ray; Humans; Kinetics; Molecular Docking Simulation; Mutagenesis, Site-Directed; Protein Binding; Structure-Activity Relationship; Sulfonamides; Thermodynamics; Thiazines; Thiophenes

2013
Serous retinal detachment and cystoid macular edema in a patient with Wyburn-Mason syndrome.
    Seminars in ophthalmology, 2015, Volume: 30, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arteriovenous Fistula; Drug Therapy, Combination; Fluorescein Angiography; Glucocorticoids; Humans; Ketorolac Tromethamine; Macular Edema; Magnetic Resonance Imaging; Male; Neurocutaneous Syndromes; Prednisolone; Retinal Detachment; Subretinal Fluid; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Triamcinolone Acetonide

2015
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
    La Clinica terapeutica, 2013, Volume: 164, Issue:5

    Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Drug Therapy, Combination; Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Hypertension; Miotics; Mydriasis; Ocular Hypertension; Pilocarpine; Prostaglandins F; Quinoxalines; Sulfonamides; Syndrome; Thiophenes; Timolol

2013
[Signs and symptoms of ocular surface disease in patients on topical intraocular pressure-lowering therapy].
    Arquivos brasileiros de oftalmologia, 2013, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blepharitis; Cornea; Cross-Sectional Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Lacrimal Apparatus Diseases; Male; Microscopy, Acoustic; Middle Aged; Ocular Hypertension; Severity of Illness Index; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Young Adult

2013
A combination of topical and systemic carbonic anhydrase in the treatment of chromosome X-linked retinoschisis.
    Archivos de la Sociedad Espanola de Oftalmologia, 2014, Volume: 89, Issue:8

    Topics: Acetazolamide; Administration, Topical; Adolescent; Carbonic Anhydrase Inhibitors; Humans; Male; Retinoschisis; Sulfonamides; Thiophenes

2014
Removal of dorzolamide from biomedical wastewaters with adsorption onto graphite oxide/poly(acrylic acid) grafted chitosan nanocomposite.
    Bioresource technology, 2014, Volume: 152

    Topics: Acrylic Resins; Adsorption; Chitosan; Graphite; Hydrogen-Ion Concentration; Medical Waste; Nanocomposites; Oxides; Solutions; Spectroscopy, Fourier Transform Infrared; Sulfonamides; Thiophenes; Wastewater; Water Pollutants, Chemical

2014
Development and characterization of nano-fiber patch for the treatment of glaucoma.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Mar-12, Volume: 53

    Topics: Animals; Antihypertensive Agents; Drug Delivery Systems; Glaucoma; Nanofibers; Rabbits; Sulfonamides; Thiophenes; Timolol

2014
[Current trend of glaucoma medication with various eye drops].
    Nippon Ganka Gakkai zasshi, 2013, Volume: 117, Issue:10

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Glaucoma; Humans; Latanoprost; Neuroprotective Agents; Ophthalmic Solutions; Ophthalmology; Prostaglandins; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes

2013
In situ gelling dorzolamide loaded chitosan nanoparticles for the treatment of glaucoma.
    Carbohydrate polymers, 2014, Feb-15, Volume: 102

    Topics: Animals; Calorimetry, Differential Scanning; Carbonic Anhydrase Inhibitors; Chitosan; Glaucoma; Goats; Humans; In Vitro Techniques; Nanoparticles; Radionuclide Imaging; Sulfonamides; Thiophenes; X-Ray Diffraction

2014
Retinal Dystrophy with Intraretinal Cystoid Spaces Associated with Mutations in the Crumbs Homologue (CRB1) Gene.
    Ophthalmic genetics, 2015, Volume: 36, Issue:3

    Topics: Acetazolamide; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Eye Proteins; Female; Humans; Macular Edema; Male; Membrane Proteins; Mutation; Nerve Tissue Proteins; Pedigree; Polymerase Chain Reaction; Retinal Dystrophies; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2015
Novel spectrophotometric methods for simultaneous determination of timolol and dorzolamide in their binary mixture.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, May-21, Volume: 126

    Topics: Antihypertensive Agents; Drug Combinations; Spectrophotometry; Sulfonamides; Thiophenes; Timolol

2014
Dorzolamide cyclodextrin nanoparticle suspension eye drops and Trusopt in rabbit.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:6

    Topics: Animals; Carbonic Anhydrase Inhibitors; Delayed-Action Preparations; Drug Delivery Systems; gamma-Cyclodextrins; Harderian Gland; Inflammation; Nanoparticles; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes

2014
A prospective research study of anti-glaucoma drugs prescribing, utilization pattern and adverse drug reaction recording in a university hospital.
    Drug research, 2015, Volume: 65, Issue:3

    Topics: Acetazolamide; Adult; Adverse Drug Reaction Reporting Systems; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; Glaucoma; Hospitals, University; Humans; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol

2015
Medical management of acute ocular hypertension in a western screech owl (Megascops kennicottii).
    Journal of avian medicine and surgery, 2014, Volume: 28, Issue:1

    Topics: Acute Disease; Animals; Bird Diseases; Carbonic Anhydrase Inhibitors; Diclofenac; Mannitol; Meloxicam; Ocular Hypertension; Strigiformes; Sulfonamides; Thiazines; Thiazoles; Thiophenes

2014
Dorzolamide-loaded PLGA/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits.
    Colloids and surfaces. B, Biointerfaces, 2014, Oct-01, Volume: 122

    Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Ocular Hypertension; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Radionuclide Imaging; Sulfonamides; Thiophenes; Vitamin A; Vitamin E

2014
Simultaneous determination of dorzolomide and timolol in aqueous humor: a novel salting out liquid-liquid microextraction combined with HPLC.
    Talanta, 2014, Volume: 130

    Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Limit of Detection; Liquid Phase Microextraction; Male; Rabbits; Solvents; Sulfonamides; Thiophenes; Timolol; Tissue Distribution

2014
Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells.
    Experimental eye research, 2014, Volume: 128

    Topics: Acidosis; Animals; Arterioles; Benzopyrans; Bradykinin; Carbonic Anhydrase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Lactates; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Quinoxalines; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasodilation

2014
Efficacy of topical dorzolamide therapy for cystoid macular edema in a patient with MFRP-related nanophthalmos-retinitis pigmentosa-foveoschisis-optic disk drusen syndrome.
    Retinal cases & brief reports, 2015,Winter, Volume: 9, Issue:1

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Female; Frameshift Mutation; Humans; Macular Edema; Membrane Proteins; Microphthalmos; Middle Aged; Optic Disk Drusen; Retinitis Pigmentosa; Sulfonamides; Syndrome; Thiophenes; Treatment Outcome

2015
Mechanisms of human erythrocytic bioactivation of nitrite.
    The Journal of biological chemistry, 2015, Jan-09, Volume: 290, Issue:2

    Topics: Blood Platelets; Carbonic Anhydrases; Electron Spin Resonance Spectroscopy; Erythrocytes; Hemoglobins; Humans; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidation-Reduction; Signal Transduction; Sulfonamides; Thiophenes

2015
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
    European journal of pharmacology, 2015, Feb-15, Volume: 749

    Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol

2015
Detection of protein-small molecule binding using a self-referencing external cavity laser biosensor.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2014, Volume: 2014

    Topics: Biosensing Techniques; Carbonic Anhydrase II; Enzymes, Immobilized; Humans; Indoles; Lasers; Protein Binding; Serum Albumin; Small Molecule Libraries; Sulfonamides; Thiophenes; Warfarin

2014
Totally one-sided: painless unilateral proptosis.
    The American journal of medicine, 2015, Volume: 128, Issue:4

    Topics: Aged, 80 and over; Antihypertensive Agents; Arteriovenous Fistula; Brimonidine Tartrate; Carotid Artery, Internal; Cavernous Sinus; Cerebral Angiography; Diagnosis, Differential; Exophthalmos; Female; Humans; Intraocular Pressure; Levobunolol; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Tomography, X-Ray Computed; Treatment Outcome; Vision Disorders

2015
Efficacy and prognostic factors of response to carbonic anhydrase inhibitors in management of cystoid macular edema in retinitis pigmentosa.
    Investigative ophthalmology & visual science, 2015, Feb-10, Volume: 56, Issue:3

    Topics: Acetazolamide; Administration, Oral; Adult; Carbonic Anhydrase Inhibitors; Cohort Studies; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome

2015
Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure.
    Journal of medicinal chemistry, 2015, Mar-26, Volume: 58, Issue:6

    Topics: Animals; Carbonic Anhydrase Inhibitors; Drug Design; Glaucoma; Intraocular Pressure; Male; Nitric Oxide Donors; Rabbits; Sulfonamides; Thiazines; Thiophenes

2015
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
    Bioorganic & medicinal chemistry, 2015, Apr-15, Volume: 23, Issue:8

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Molecular Sequence Data; Nostoc commune; Sequence Alignment; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines; Thiophenes

2015
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Animals; Antihypertensive Agents; Carbon Disulfide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Male; Molecular Docking Simulation; Morpholines; Piperazines; Piperidines; Quinuclidines; Rabbits; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Thiocarbamates; Thiophenes

2015
Retinal vein-to-vein anastomoses in Sturge-Weber syndrome documented by ultra-widefield fluorescein angiography.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2015, Volume: 19, Issue:3

    Topics: Carbonic Anhydrase Inhibitors; Child; Fluorescein Angiography; Glaucoma; Humans; Intraocular Pressure; Male; Retinal Vein; Sturge-Weber Syndrome; Sulfonamides; Thiophenes; Vascular Fistula; Visual Acuity

2015
Dual drug delivery from vitamin E loaded contact lenses for glaucoma therapy.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 94

    Topics: Animals; Antihypertensive Agents; Biological Availability; Contact Lenses; Delayed-Action Preparations; Dogs; Drug Liberation; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Vitamin E

2015
Spectroscopic and molecular modeling studies on binding of dorzolamide to bovine and human carbonic anhydrase II.
    International journal of biological macromolecules, 2015, Volume: 80

    Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Catalytic Domain; Cattle; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Spectrum Analysis; Substrate Specificity; Sulfonamides; Thermodynamics; Thiophenes

2015
Dorzolamide synergizes the antitumor activity of mitomycin C against Ehrlich's carcinoma grown in mice: role of thioredoxin-interacting protein.
    Naunyn-Schmiedeberg's archives of pharmacology, 2015, Volume: 388, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Carrier Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Mitomycin; Sulfonamides; Thiophenes; Thioredoxins

2015
CRB1-Related Maculopathy With Cystoid Macular Edema.
    JAMA ophthalmology, 2015, Volume: 133, Issue:11

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Diseases in Twins; DNA Mutational Analysis; Electroretinography; Eye Proteins; Female; Fluorescein Angiography; Humans; Macular Edema; Membrane Proteins; Mutation; Nerve Tissue Proteins; Ophthalmic Solutions; Retinal Dystrophies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Twins, Monozygotic; Visual Acuity

2015
The effect of prophylactic topical carbonic anhydrase inhibitors in canine primary closed-angle glaucoma.
    The Journal of small animal practice, 2015, Volume: 56, Issue:11

    Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol

2015
Rapid and selective removal of preservative from ophthalmic formulations during eyedrops instillation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 97, Issue:Pt A

    Topics: Antihypertensive Agents; Benzalkonium Compounds; Drug Packaging; Hydrogels; Hydrophobic and Hydrophilic Interactions; Ophthalmic Solutions; Permeability; Polyhydroxyethyl Methacrylate; Preservatives, Pharmaceutical; Sterilization; Sulfonamides; Thiophenes; Timolol

2015
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
    BioMed research international, 2015, Volume: 2015

    Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2015
    Journal of social and clinical psychology, 2015, Volume: 34, Issue:9

    Topics: Acid-Base Imbalance; Acidosis, Renal Tubular; Aged; Air Pollution, Indoor; Amino Acid Substitution; Animals; Animals, Newborn; Anti-Bacterial Agents; Antibodies, Neutralizing; Apoptosis; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Bone Marrow Transplantation; Carbonic Anhydrase Inhibitors; Castleman Disease; Cat Diseases; Cats; Cell Proliferation; Cell- and Tissue-Based Therapy; Chemical and Drug Induced Liver Injury; Chemotaxis, Leukocyte; Clinical Trials as Topic; Coated Materials, Biocompatible; Diagnosis, Differential; Disease Models, Animal; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Genotype; Granuloma, Foreign-Body; Heart Failure; Hepacivirus; Hepatitis C; Horse Diseases; Horses; Housing; Humans; Hypercalcemia; Hypokalemia; Immunophenotyping; In Vitro Techniques; Liver; Liver Function Tests; Lymphocytes; Macrophages; Male; Medicine, Chinese Traditional; Metabolomics; Mice; Mice, Inbred C57BL; Middle Aged; Models, Animal; Mutation; Myocardial Ischemia; Neovascularization, Physiologic; Neutrophil Infiltration; Ocular Hypertension; Ophthalmic Solutions; Parathyroid Hormone; Particulate Matter; Polyethylene Terephthalates; Prednisolone; Prospective Studies; Prosthesis Design; Prosthesis-Related Infections; Rats; Rats, Wistar; Reactive Oxygen Species; Rifampin; Saponins; Sepsis; Skin; Stem Cells; Stroke Volume; Sulfonamides; Texas; Thiophenes; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Viral Hepatitis Vaccines; Viral Nonstructural Proteins; Viral Proteins; Vitamin D; Wound Healing

2015
Keratitis in six dogs after topical treatment with carbonic anhydrase inhibitors for glaucoma.
    Journal of the American Veterinary Medical Association, 2015, Dec-15, Volume: 247, Issue:12

    Topics: Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma; Keratitis; Male; Sulfonamides; Thiazines; Thiophenes

2015
Dorzolamide-induced relaxation of isolated rabbit ciliary arteries mediated by inhibition of extracellular calcium influx.
    Japanese journal of ophthalmology, 2016, Volume: 60, Issue:2

    Topics: Animals; Calcium; Calcium Channels; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Space; Fluorophotometry; Isometric Contraction; Muscle, Smooth, Vascular; Optic Nerve; Potassium; Rabbits; Sulfonamides; Thiophenes; Vasodilation; Vasodilator Agents

2016
Fundus Autofluorescence and SD-OCT Document Rapid Progression in Autosomal Dominant Vitreoretinochoroidopathy (ADVIRC) Associated with a c.256G > A Mutation in BEST1.
    Ophthalmic genetics, 2016, Volume: 37, Issue:2

    Topics: Adult; Bestrophins; Carbonic Anhydrase Inhibitors; Child; Chloride Channels; Choroid Diseases; Disease Progression; Electroretinography; Eye Diseases, Hereditary; Eye Proteins; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Genes, Dominant; Humans; Macular Edema; Male; Middle Aged; Mutation, Missense; Optical Imaging; Pedigree; Polymerase Chain Reaction; Retinal Degeneration; Sequence Analysis, DNA; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2016
Secondary pigmentary glaucoma associated with 1-piece foldable intraocular lens in the ciliary sulcus.
    Journal of cataract and refractive surgery, 2015, Volume: 41, Issue:12

    Topics: Aged, 80 and over; Antihypertensive Agents; Ciliary Body; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Phacoemulsification; Prosthesis Design; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Tonometry, Ocular; Visual Acuity

2015
Cystoid macular lesions are resistant to topical dorzolamide treatment in enhanced S-cone syndrome child.
    Documenta ophthalmologica. Advances in ophthalmology, 2016, Volume: 132, Issue:1

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Electroretinography; Eye Diseases, Hereditary; Fluorescein Angiography; Humans; Macular Edema; Male; Ophthalmic Solutions; Retina; Retinal Degeneration; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Visual Acuity

2016
Effects of dorzolamide/timolol fixed combination on retrobulbar hemodynamics in pseudoexfoliative glaucoma.
    The Kaohsiung journal of medical sciences, 2016, Volume: 32, Issue:1

    Topics: Aged; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Exfoliation Syndrome; Eye; Female; Hemodynamics; Humans; Male; Middle Aged; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2016
Topical carbonic anhydrase inhibitors in macular edema associated with Alström syndrome.
    Ophthalmic genetics, 2016, Volume: 37, Issue:4

    Topics: Administration, Topical; Alstrom Syndrome; Carbonic Anhydrase Inhibitors; Cell Cycle Proteins; Female; Humans; Infant; Macular Edema; Ophthalmic Solutions; Proteins; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2016
Macular cystoid spaces in patients with retinal dystrophy.
    Ophthalmic genetics, 2016, Volume: 37, Issue:4

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Child; DNA Mutational Analysis; Eye Proteins; Female; Humans; Macular Edema; Male; Middle Aged; Retinal Dystrophies; Retrospective Studies; Sulfonamides; Thiophenes; Visual Acuity

2016
Effects of Dorzolamide on Retinal and Choroidal Blood Flow in the DBA/2J Mouse Model of Glaucoma.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Choroid; Disease Models, Animal; Glaucoma; Intraocular Pressure; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Treatment Outcome

2016
Single-eye trial of a topical carbonic anhydrase inhibitor versus intravitreal bevacizumab for the treatment of taxane drug-induced cystoid macula oedema.
    BMJ case reports, 2016, Apr-19, Volume: 2016

    Topics: Administration, Topical; Aged; Angiogenesis Inhibitors; Bevacizumab; Bridged-Ring Compounds; Carbonic Anhydrase Inhibitors; Humans; Intravitreal Injections; Macular Edema; Male; Sulfonamides; Taxoids; Thiophenes

2016
Efficacy of Bimatoprost Plus Timolol Fixed Combination in Open Angle Glaucoma Patients Previously Treated with Dorzolamide Plus Timolol Fixed Combination.
    Current eye research, 2016, Volume: 41, Issue:11

    Topics: Aged; Antihypertensive Agents; Bimatoprost; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome

2016
In vitro and in vivo corneal effects of latanoprost combined with brimonidine, timolol, dorzolamide, or brinzolamide.
    European journal of pharmacology, 2016, Sep-15, Volume: 787

    Topics: Animals; Brimonidine Tartrate; Cell Survival; Electric Impedance; Epithelium, Corneal; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol

2016
Dramatic regression of macular and peripheral retinoschisis with dorzolamide 2 % in X-linked retinoschisis: a case report.
    Journal of medical case reports, 2016, Jun-01, Volume: 10, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Humans; Infant; Male; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome

2016
Subconjunctival Delivery of Dorzolamide-Loaded Poly(ether-anhydride) Microparticles Produces Sustained Lowering of Intraocular Pressure in Rabbits.
    Molecular pharmaceutics, 2016, 09-06, Volume: 13, Issue:9

    Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Ethylamines; Female; Glaucoma; Intraocular Pressure; Lactic Acid; Male; Oleic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Sodium Dodecyl Sulfate; Sulfonamides; Thiophenes

2016
Aqueous Flow Measured by Fluorophotometry in the Mouse.
    Investigative ophthalmology & visual science, 2016, Jul-01, Volume: 57, Issue:8

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Anesthetics, Dissociative; Animals; Anterior Chamber; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cornea; Ethanol; Female; Fluorescein; Fluorescent Dyes; Fluorophotometry; Hypnotics and Sedatives; Ketamine; Male; Mice; Organ Size; Sulfonamides; Thiophenes; Timolol; Xylazine

2016
New Electrochemically-Modified Carbon Paste Inclusion β-Cyclodextrin and Carbon Nanotubes Sensors for Quantification of Dorzolamide Hydrochloride.
    International journal of molecular sciences, 2016, Dec-02, Volume: 17, Issue:12

    Topics: beta-Cyclodextrins; Biosensing Techniques; Calibration; Carbon; Electrochemistry; Hydrogen-Ion Concentration; Limit of Detection; Nanotubes, Carbon; Ophthalmic Solutions; Plasticizers; Reproducibility of Results; Sulfonamides; Temperature; Thiophenes; Time Factors

2016
Maximizing cost-effectiveness by adjusting treatment strategy according to glaucoma severity.
    Medicine, 2016, Volume: 95, Issue:52

    Topics: Age Factors; Antihypertensive Agents; Brazil; Cost-Benefit Analysis; Glaucoma, Open-Angle; Health Care Costs; Humans; Lasers, Gas; Markov Chains; Prostaglandins; Quality of Life; Quality-Adjusted Life Years; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Watchful Waiting

2016
Effect of prophylactic topical hypotensive medications in reducing the incidence of postoperative ocular hypertension after phacoemulsification in dogs.
    Veterinary ophthalmology, 2017, Volume: 20, Issue:6

    Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Female; Incidence; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Pre-Exposure Prophylaxis; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol

2017
Enhanced ocular efficacy of topically-delivered dorzolamide with nanostructured mucoadhesive microparticles.
    International journal of pharmaceutics, 2017, Apr-30, Volume: 522, Issue:1-2

    Topics: Adhesives; Administration, Ophthalmic; Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Drug Compounding; Intraocular Pressure; Lactic Acid; Male; Mucous Membrane; Nanofibers; Ophthalmic Solutions; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propylene Glycol; Rabbits; Solubility; Sulfonamides; Thiophenes

2017
STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS: RESPONSE TO TOPICAL DORZOLAMIDE THERAPY.
    Retinal cases & brief reports, 2019,Fall, Volume: 13, Issue:4

    Topics: Adult; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Fluorescein Angiography; Fovea Centralis; Fundus Oculi; Humans; Macula Lutea; Male; Ophthalmic Solutions; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Acuity

2019
Carbonic Anhydrase Inhibitors Induce Developmental Toxicity During Zebrafish Embryogenesis, Especially in the Inner Ear.
    Marine biotechnology (New York, N.Y.), 2017, Volume: 19, Issue:5

    Topics: Acetazolamide; Animal Fins; Animals; Apoptosis; Calcium; Carbonic Anhydrase Inhibitors; Cardiomegaly; Ear, Inner; Embryo, Nonmammalian; Embryonic Development; Ethoxzolamide; Hair Cells, Auditory; Otolithic Membrane; Sulfonamides; Swimming; Thiophenes; Zebrafish

2017
Validated HPLC-DAD Method for the Simultaneous Determination of Six Selected Drugs Used in the Treatment of Glaucoma.
    Journal of AOAC International, 2018, Jul-01, Volume: 101, Issue:4

    Topics: Acetazolamide; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Glaucoma; Humans; Levobunolol; Sulfonamides; Thiophenes; Timolol

2018
Isotretinoin-induced Angle Closure and Myopic Shift.
    Journal of glaucoma, 2017, Volume: 26, Issue:11

    Topics: Acne Vulgaris; Adult; Antihypertensive Agents; Dermatologic Agents; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Isotretinoin; Microscopy, Acoustic; Myopia; Sulfonamides; Thiophenes; Timolol

2017
The application of artificial neural networks and support vector regression for simultaneous spectrophotometric determination of commercial eye drop contents.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2018, Mar-15, Volume: 193

    Topics: Humans; Neural Networks, Computer; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Sulfonamides; Support Vector Machine; Thiophenes; Timolol

2018
Metabolic acidosis and anaemia associated with dorzolamide in a patient with impaired renal function.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:4

    Topics: Acidosis; Administration, Ophthalmic; Anemia; Carbonic Anhydrase Inhibitors; Fatigue; Glaucoma; Humans; Male; Middle Aged; Renal Insufficiency; Sulfonamides; Thiophenes

2018
Treatment of cystoid macular edema in homozygous twins with glutathione synthetase deficiency and retinal dystrophy.
    Journal francais d'ophtalmologie, 2018, Volume: 41, Issue:2

    Topics: Acetazolamide; Administration, Oral; Amino Acid Metabolism, Inborn Errors; Child; Combined Modality Therapy; Diseases in Twins; Drug Therapy, Combination; Glutathione Synthase; Humans; Macular Edema; Male; Ophthalmic Solutions; Retinal Dystrophies; Sulfonamides; Thiophenes

2018
Enhancement of pharmacokinetic and pharmacological behavior of ocular dorzolamide after factorial optimization of self-assembled nanostructures.
    PloS one, 2018, Volume: 13, Issue:2

    Topics: Animals; Aqueous Humor; Biological Availability; Delayed-Action Preparations; Drug Compounding; Glaucoma; Half-Life; Intraocular Pressure; Male; Nanostructures; Ophthalmic Solutions; Particle Size; Permeability; Phosphatidylcholines; Rabbits; Sulfonamides; Thiophenes

2018
Paradoxical Anatomic Response to Topical Carbonic Anhydrase Inhibitor in X-linked Retinoschisis.
    Ophthalmic surgery, lasers & imaging retina, 2018, 02-01, Volume: 49, Issue:2

    Topics: Carbonic Anhydrase Inhibitors; Child; Humans; Macula Lutea; Male; Retinoschisis; Sulfonamides; Thiophenes

2018
Retrospective cohort study exploring whether an association exists between spatial distribution of cystoid spaces in cystoid macular oedema secondary to retinitis pigmentosa and response to treatment with carbonic anhydrase inhibitors.
    The British journal of ophthalmology, 2019, Volume: 103, Issue:2

    Topics: Acetazolamide; Adolescent; Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Humans; Macular Edema; Male; Middle Aged; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Tomography, Optical Coherence; Visual Acuity; Visual Field Tests; Young Adult

2019
Effect of topical dorzolamide therapy on cystoid macular edema in hydroxychloroquine retinopathy.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2018, Volume: 53, Issue:3

    Topics: Administration, Topical; Adult; Aged; Antirheumatic Agents; Carbonic Anhydrase Inhibitors; Female; Fluorescein Angiography; Fundus Oculi; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Macular Edema; Retinal Diseases; Sulfonamides; Thiophenes; Visual Acuity

2018
Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic evaluation in rabbits.
    Drug delivery, 2018, Volume: 25, Issue:1

    Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Cholesterol; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Eye; Gels; Glaucoma; Intraocular Pressure; Liposomes; Male; Ophthalmic Solutions; Particle Size; Rabbits; Sulfonamides; Surface-Active Agents; Thiophenes

2018
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
    Archivos de la Sociedad Espanola de Oftalmologia, 2018, Volume: 93, Issue:10

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjunctivitis, Allergic; Cyclopentolate; Drug Therapy, Combination; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Granuloma; Humans; Latanoprost; Lubricant Eye Drops; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Sulfonamides; Thiophenes; Timolol; Uveitis, Anterior

2018
TOPICAL DORZOLAMIDE FOR CYSTOID MACULAR EDEMA IN BIETTI CRYSTALLINE RETINAL DYSTROPHY.
    Retinal cases & brief reports, 2021, May-01, Volume: 15, Issue:3

    Topics: Administration, Ophthalmic; Adult; Carbonic Anhydrase Inhibitors; Corneal Dystrophies, Hereditary; Female; Humans; Macular Edema; Multimodal Imaging; Ophthalmic Solutions; Retinal Diseases; Sulfonamides; Thiophenes; Visual Acuity

2021
Metabolic acidosis during general anaesthesia: presumed systemic toxicity caused by topical dorzolamide in a dog.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:6

    Topics: Acidosis; Administration, Topical; Anesthesia, General; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma; Sulfonamides; Thiophenes

2018
A Novel Method to Eliminate Preservatives in Eye Drops.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2018, Volume: 34, Issue:8

    Topics: Anti-Bacterial Agents; Bacteria; Humans; Microbial Sensitivity Tests; Moxifloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Sulfonamides; Thiophenes; Timolol

2018
Generalised nevus flammeus, episcleral capillary malformation and glaucoma.
    BMJ case reports, 2018, Oct-21, Volume: 2018

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Adult; Capillaries; Carbonic Anhydrase Inhibitors; Cryosurgery; Diagnosis, Differential; Female; Glaucoma; Humans; Port-Wine Stain; Sulfonamides; Thiophenes; Timolol; Vascular Malformations

2018
Double trouble: exudative hypertensive retinopathy in a patient with retinitis pigmentosa.
    BMJ case reports, 2018, Nov-08, Volume: 2018

    Topics: Adult; Anti-Inflammatory Agents; Antihypertensive Agents; Diagnosis, Differential; Female; Fluorescein Angiography; Humans; Hypertensive Retinopathy; Retina; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Triamcinolone Acetonide; Young Adult

2018
Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal Arteries.
    International journal of molecular sciences, 2019, Jan-22, Volume: 20, Issue:3

    Topics: Acetazolamide; Animals; Benzolamide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Muscle, Smooth, Vascular; Retinal Artery; Sulfonamides; Swine; Thiophenes; Vasodilation

2019
Topical Aqueous Suppression and Closure of Idiopathic Full-Thickness Macular Holes.
    Ophthalmic surgery, lasers & imaging retina, 2019, 02-01, Volume: 50, Issue:2

    Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Humans; Male; Middle Aged; Retinal Perforations; Sulfonamides; Thiophenes; Treatment Outcome

2019
A versatile HPLC method with an isocratic single mobile phase system for simultaneous determination of anti-glaucoma formulations containing timolol.
    Annales pharmaceutiques francaises, 2019, Volume: 77, Issue:4

    Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Chromatography, High Pressure Liquid; Drug Combinations; Drug Compounding; Glaucoma; Limit of Detection; Ophthalmic Solutions; Reference Standards; Reproducibility of Results; Sulfonamides; Thiazines; Thiophenes; Timolol

2019
Corneal sterile infiltration induced by topical use of ocular hypotensive agent.
    European journal of ophthalmology, 2020, Volume: 30, Issue:5

    Topics: Aged; Antihypertensive Agents; Bimatoprost; Blepharitis; Brimonidine Tartrate; Conjunctivitis; Corneal Neovascularization; Corneal Opacity; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Low Tension Glaucoma; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Thiophenes

2020
Designing of a pH-Triggered Carbopol®/HPMC In Situ Gel for Ocular Delivery of Dorzolamide HCl: In Vitro, In Vivo, and Ex Vivo Evaluation.
    AAPS PharmSciTech, 2019, Jun-03, Volume: 20, Issue:5

    Topics: Acrylic Resins; Administration, Ophthalmic; Animals; Antihypertensive Agents; Cornea; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Gels; Glaucoma; Hydrogen-Ion Concentration; Hypromellose Derivatives; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Sulfonamides; Swine; Thiophenes

2019
Effect of topical glaucoma medication on tear lipid layer thickness in patients with unilateral glaucoma.
    Indian journal of ophthalmology, 2019, Volume: 67, Issue:8

    Topics: Administration, Ophthalmic; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Sectional Studies; Drug Combinations; Dry Eye Syndromes; Female; Gonioscopy; Humans; Interferometry; Intraocular Pressure; Lipid Metabolism; Low Tension Glaucoma; Male; Meibomian Gland Dysfunction; Middle Aged; Ophthalmic Solutions; Sulfonamides; Tears; Thiophenes; Timolol; Tonometry, Ocular

2019
Pigmented paravenous retinochoroidal atrophy associated with unilateral cystoid macular oedema.
    BMJ case reports, 2019, Aug-10, Volume: 12, Issue:8

    Topics: Aged; Angiogenesis Inhibitors; Bevacizumab; Carbonic Anhydrase Inhibitors; Eye Diseases, Hereditary; Fluorescein Angiography; Humans; Injections, Intraocular; Macular Edema; Male; Retinal Degeneration; Sulfonamides; Thiophenes; Tomography, Optical Coherence

2019
Leucaena leucocephala (Lam.) galactomannan nanoparticles: Optimization and characterization for ocular delivery in glaucoma treatment.
    International journal of biological macromolecules, 2019, Oct-15, Volume: 139

    Topics: Adhesiveness; Animals; Drug Carriers; Drug Liberation; Eye; Fabaceae; Galactose; Glaucoma; Goats; Mannans; Nanoparticles; Permeability; Sulfonamides; Thiophenes

2019
Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide for glaucoma treatment: In vitro and in vivo evaluation.
    International journal of pharmaceutics, 2019, Oct-30, Volume: 570

    Topics: Animals; Cellulose; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Eye; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Polymers; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Tissue Distribution

2019
Bilateral giant macular schisis in a case of Goldmann-Favre syndrome.
    BMJ case reports, 2019, Sep-26, Volume: 12, Issue:9

    Topics: Antihypertensive Agents; Diagnosis, Differential; Electroretinography; Eye Diseases, Hereditary; Humans; Macula Lutea; Male; Night Blindness; Retinal Degeneration; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Vision Disorders; Young Adult

2019
Effect of Formulation Variables and Gamma Sterilization on Transcorneal Permeation and Stability of Proniosomal Gels as Ocular Platforms for Antiglaucomal Drug.
    AAPS PharmSciTech, 2020, Feb-03, Volume: 21, Issue:3

    Topics: Animals; Cornea; Drug Compounding; Drug Stability; Gamma Rays; Gels; Glaucoma; Liposomes; Male; Permeability; Rabbits; Sterilization; Sulfonamides; Thiophenes

2020
Reversible Corneal Endothelial Abnormalities With Netarsudil.
    Journal of glaucoma, 2020, Volume: 29, Issue:6

    Topics: Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Remission Induction; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Withholding Treatment

2020
Are P Values Enough?
    JAMA ophthalmology, 2020, 05-01, Volume: 138, Issue:5

    Topics: Humans; Macular Degeneration; Sulfonamides; Thiophenes; Timolol

2020
The Carbonic Anhydrase Inhibitor Dorzolamide Stimulates the Differentiation of Human Meibomian Gland Epithelial Cells.
    Current eye research, 2020, Volume: 45, Issue:12

    Topics: Biomarkers; Carbonic Anhydrase Inhibitors; Cell Differentiation; Cell Proliferation; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Humans; Immunoblotting; Lipid Metabolism; Lysosomes; Meibomian Glands; Phospholipids; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides; Thiophenes

2020
Effect of Topical Dorzolamide on Cystoid Macular Edema in Retinitis Pigmentosa.
    Ophthalmology. Retina, 2020, Volume: 4, Issue:10

    Topics: Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Macula Lutea; Macular Edema; Male; Ophthalmic Solutions; Retinitis Pigmentosa; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity

2020
Dramatic response to topical dorzolamide in X-linked retinoschisis.
    Indian journal of ophthalmology, 2020, Volume: 68, Issue:7

    Topics: Humans; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence

2020
Allergic contact dermatitis due to dorzolamide eyedrops.
    Contact dermatitis, 2021, Volume: 84, Issue:1

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dermatitis, Allergic Contact; Eyelids; Facial Dermatoses; Female; Humans; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes

2021
Prophylactic anti-glaucoma therapy in dogs with primary glaucoma: A practitioner survey of current medical protocols.
    Veterinary ophthalmology, 2021, Volume: 24 Suppl 1

    Topics: Animals; Dog Diseases; Dogs; Female; Glaucoma; Health Care Surveys; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol

2021
Optimization to development of chitosan decorated polycaprolactone nanoparticles for improved ocular delivery of dorzolamide: In vitro, ex vivo and toxicity assessments.
    International journal of biological macromolecules, 2020, Nov-15, Volume: 163

    Topics: Administration, Ophthalmic; Animals; Chitosan; Drug Compounding; Drug Delivery Systems; Nanoparticles; Particle Size; Polyesters; Sulfonamides; Thiophenes

2020
Animal model of assessing cerebrovascular functional reserve by imaging photoplethysmography.
    Scientific reports, 2020, 11-04, Volume: 10, Issue:1

    Topics: Animals; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Cerebrovascular Disorders; Heart Rate; Male; Models, Animal; Photoplethysmography; Rats, Wistar; Sulfonamides; Thiophenes

2020
Necrotising fungal scleritis with full-thickness scleral melt and circumferential progression: a novel debridement approach.
    BMJ case reports, 2020, Dec-28, Volume: 13, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Agaricales; Antifungal Agents; Diagnosis, Differential; Disease Progression; Eye Infections, Fungal; Eye Pain; Female; Humans; Scleritis; Sulfonamides; Thiophenes; Timolol

2020
Resolution of bilateral foveal cysts in dome-shaped macula after treatment with topical dorzolamide.
    BMJ case reports, 2021, Jan-06, Volume: 14, Issue:1

    Topics: Administration, Ophthalmic; Carbonic Anhydrase Inhibitors; Child, Preschool; Cysts; Fluorescein Angiography; Fovea Centralis; Humans; Male; Retinal Diseases; Subretinal Fluid; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity

2021
Simultaneous determination of dorzolamide and timolol by first-order derivative UV spectroscopy in simulated biological fluid for in vitro drug release testing.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021, Jul-05, Volume: 255

    Topics: Antihypertensive Agents; Drug Combinations; Drug Liberation; Ophthalmic Solutions; Reproducibility of Results; Sulfonamides; Thiophenes; Timolol

2021
Optical Coherence Tomography Angiography Vessel Density Changes in Normal-tension Glaucoma Treated With Carteolol, Brimonidine, or Dorzolamide.
    Journal of glaucoma, 2021, 08-01, Volume: 30, Issue:8

    Topics: Angiography; Brimonidine Tartrate; Carteolol; Female; Fluorescein Angiography; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Nerve Fibers; Retinal Ganglion Cells; Retinal Vessels; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Fields

2021
Spectrally Resolved Estimation of Water Entropy in the Active Site of Human Carbonic Anhydrase II.
    Journal of chemical theory and computation, 2021, Aug-10, Volume: 17, Issue:8

    Topics: Carbonic Anhydrase II; Catalytic Domain; Entropy; Humans; Hydrogen Bonding; Lipid Bilayers; Protein Binding; Sulfonamides; Thiophenes; Water

2021
Regression of taxane-related cystoid macular edema after topical dorzolamide treatment: two case reports.
    Journal of medical case reports, 2021, Jul-21, Volume: 15, Issue:1

    Topics: Aged; Female; Humans; Macular Edema; Male; Quality of Life; Sulfonamides; Taxoids; Thiophenes; Tomography, Optical Coherence

2021
RECURRENCE RATE OF CYSTOID MACULAR EDEMA WITH TOPICAL DORZOLAMIDE TREATMENT AND ITS RISK FACTORS IN RETINITIS PIGMENTOSA.
    Retina (Philadelphia, Pa.), 2022, 01-01, Volume: 42, Issue:1

    Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Female; Follow-Up Studies; Humans; Incidence; Japan; Macula Lutea; Macular Edema; Male; Middle Aged; Prospective Studies; Recurrence; Retinitis Pigmentosa; Risk Assessment; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Tomography, Optical Coherence; Visual Acuity

2022
Cases reports: Unintended anti-doping rule violation after dorzolamide use several months prior to a doping control.
    Drug testing and analysis, 2021, Volume: 13, Issue:10

    Topics: Administration, Ophthalmic; Adult; Carbonic Anhydrase Inhibitors; Doping in Sports; Female; Half-Life; Humans; Sulfonamides; Thiophenes; Time Factors

2021
Impact of dorzolamide, benzalkonium-preserved dorzolamide and benzalkonium-preserved brinzolamide on selected biomarkers of oxidative stress in the tear film.
    BMC ophthalmology, 2021, Sep-01, Volume: 21, Issue:1

    Topics: Benzalkonium Compounds; Biomarkers; Carbonic Anhydrase Inhibitors; Humans; Ophthalmic Solutions; Oxidative Stress; Sulfonamides; Thiazines; Thiophenes

2021
Clinical and Genetic Study of X-Linked Juvenile Retinoschisis in the Czech Population.
    Genes, 2021, 11-18, Volume: 12, Issue:11

    Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Czech Republic; Eye Proteins; Gene Frequency; Humans; Infant; Mutation; Pedigree; Retinoschisis; Sulfonamides; Thiophenes; Tomography, Optical Coherence

2021
Case Series: Small Full-thickness Macular Hole Treated with Topical Dorzolamide and Bevacizumab Intravitreal Injections.
    Optometry and vision science : official publication of the American Academy of Optometry, 2021, 12-01, Volume: 98, Issue:12

    Topics: Aged; Angiogenesis Inhibitors; Bevacizumab; Female; Humans; Intravitreal Injections; Retinal Perforations; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome

2021
Adverse analytical finding due to red blood cells transfusion: A rare case involving the diuretic dorzolamide.
    Drug testing and analysis, 2022, Volume: 14, Issue:10

    Topics: Chromatography, Liquid; Diuretics; Erythrocytes; Humans; Male; Sulfonamides; Tandem Mass Spectrometry; Thiophenes

2022
Reversible Corneal Decompensation Caused by a Topical Dorzolamide/Timolol Fixed Combination After Descemet Stripping Automated Endothelial Keratoplasty.
    Cornea, 2022, Sep-01, Volume: 41, Issue:9

    Topics: Aged; Corneal Diseases; Corneal Edema; Descemet Stripping Endothelial Keratoplasty; Endothelium, Corneal; Female; Humans; Sulfonamides; Thiophenes; Timolol

2022