thiophenes has been researched along with deoxyuridine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Claes, P; De Clercq, E; Herdewijn, P; Pannecouque, C; Snoeck, R; Wigerinck, P | 1 |
| Erlichman, C; Mandelbaum, S; Mitrovski, B; Pressacco, J | 1 |
| Creuven, I; Dory, M; Durant, F; Evrard, C; Evrard, G; Herdewijn, P; Olivier, A; van Aerschot, A; Wigerinck, P | 1 |
| Claes, P; De Clercq, E; Herdewijn, P; Kerremans, L; Maudgal, P; Snoeck, R; Wigerinck, P | 1 |
| Creuven, I; Durant, F; Evrard, C; Evrard, G; Herdewijn, P; Olivier, A; Van Aerschot, A; Wigerinck, P | 1 |
| Aherne, GW; Benstead, J; Clarke, SJ; Farrugia, DC; Jackman, AL; Pritchard, DM | 1 |
| Calvert, AH; Cunningham, D; Farrugia, DC; Ford, HE; Hill, ME; Jackman, AL; Judson, IR; Mitchell, F; Rees, C | 1 |
| Alesi, S; Barbarella, G; Capobianco, ML; Cazzato, A | 1 |
| Cho, HY; Hwang, GT; Lee, J | 1 |
| Fisher, RS; Hopkins, PA; Jones, AC; Magennis, SW; Nobis, D; Simmermacher, M; Tor, Y | 1 |
| Betz, K; Diederichs, K; Ghosh, P; Kropp, HM; Ludmann, S; Marx, A; Srivatsan, SG | 1 |
1 trial(s) available for thiophenes and deoxyuridine
| Article | Year |
|---|---|
Patterns of elevation of plasma 2'-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331.
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Colorectal Neoplasms; Deoxyuridine; Enzyme Inhibitors; Fluorouracil; Humans; Infusions, Intravenous; Quinazolines; Thiophenes; Thymidylate Synthase | 2002 |
10 other study(ies) available for thiophenes and deoxyuridine
| Article | Year |
|---|---|
5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Deoxyuridine; Herpesvirus 3, Human; Molecular Structure; Simplexvirus; Structure-Activity Relationship; Thiophenes; Virus Replication | 1991 |
Biochemical effects of folate-based inhibitors of thymidylate synthase in MGH-U1 cells.
Topics: Cell Survival; Deoxyuracil Nucleotides; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Glutamates; Humans; In Vitro Techniques; Indoles; Isoindoles; Quinazolines; Structure-Activity Relationship; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1994 |
Stereoelectronic properties of five anti-HSV-1 2'-deoxynucleosides analogues with heterocyclic substituents in the 5-position: a comparison with BVDU.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry, Physical; Deoxyuridine; Herpesvirus 1, Human; Molecular Structure; Stereoisomerism; Thermodynamics; Thiophenes; Thymidine Kinase; Viral Proteins; X-Ray Diffraction | 1994 |
Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogues.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxyuridine; Herpes Simplex; Herpesvirus 3, Human; Humans; Keratitis, Herpetic; Mice; Organotin Compounds; Palladium; Rabbits; Simplexvirus; Structure-Activity Relationship; Thiophenes; Virus Replication | 1993 |
Relationship between structural properties and affinity for herpes simplex virus type 1 thymidine kinase of bromine substituted 5-heteroaromatic 2'-deoxyuridines.
Topics: Antiviral Agents; Bromine; Deoxyuridine; Herpesvirus 1, Human; Humans; Structure-Activity Relationship; Thiophenes; Thymidine Kinase; X-Ray Diffraction | 1996 |
Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicity.
Topics: Animals; Antimetabolites, Antineoplastic; Deoxyuridine; Diarrhea; Digestive System; Dose-Response Relationship, Drug; Folic Acid; Intestinal Mucosa; Intestine, Large; Intestine, Small; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Weight Loss | 2000 |
Oligothiophene-5-labeled deoxyuridines for the detection of single nucleotide polymorphisms.
Topics: Base Pair Mismatch; Base Sequence; Deoxyuridine; Fluorescence; Fluorescent Dyes; Genetic Testing; Humans; Oligonucleotides; Organophosphorus Compounds; Polymorphism, Single Nucleotide; Spectrometry, Fluorescence; Thiophenes; Transition Temperature; Ultraviolet Rays | 2008 |
Highly efficient quencher-free molecular beacon systems containing 2-ethynyldibenzofuran- and 2-ethynyldibenzothiophene-labeled 2'-deoxyuridine units.
Topics: Base Pair Mismatch; Benzofurans; Circular Dichroism; Deoxyuridine; DNA Probes; Electron Transport; Fluorescent Dyes; Oligodeoxyribonucleotides; Polymorphism, Single Nucleotide; Spectrometry, Fluorescence; Thiophenes; Transition Temperature | 2013 |
Single-Molecule Detection of a Fluorescent Nucleobase Analogue via Multiphoton Excitation.
Topics: Deoxyuridine; Lasers; Nucleosides; Photons; Spectrometry, Fluorescence; Thiophenes | 2019 |
Microenvironment-Sensitive Fluorescent Nucleotide Probes from Benzofuran, Benzothiophene, and Selenophene as Substrates for DNA Polymerases.
Topics: Benzofurans; Deoxyuridine; DNA; DNA-Directed DNA Polymerase; Nucleotides; Oligonucleotides; Thiophenes | 2022 |