thiophenes has been researched along with colchicine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| de Krester, DM | 1 |
| Hannig, M; Moll, F | 1 |
| Bastow, KF; Hamel, E; Kuo, SC; Lee, KH; Mauger, A; Narayanan, VL; Tachibana, Y; Zhang, SX | 1 |
| Flynn, BL; Hamel, E; Verdier-Pinard, P | 1 |
| Flynn, BL; Flynn, GP; Hamel, E; Jung, MK | 1 |
| Alloatti, D; Baruchello, R; Bucci, F; Carminati, P; Castorina, M; Giannini, G; Guglielmi, MB; Marcellini, M; Pavani, MG; Pisano, C; Riccioni, T; Rizzi, M; Romagnoli, R; Rondanin, R; Simoni, D | 1 |
| Baraldi, PG; Borgatti, M; Fruttarolo, F; Gambari, R; Hamel, E; Jung, MK; Pavani, MG; Piccagli, L; Preti, D; Romagnoli, R; Tabrizi, MA | 1 |
| Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E; Zuse, A | 2 |
| Balzarini, J; Baraldi, PG; Brancale, A; Carrion, MD; Di Cristina, A; Fruttarolo, F; Grimaudo, S; Hadfield, JA; Hamel, E; Lopez Cara, C; Pavani, MG; Preti, D; Romagnoli, R; Tabrizi, MA; Tolomeo, M | 1 |
| Balzarini, J; Baraldi, PG; Brancale, A; Cara, CL; Carrion, MD; Cruz-Lopez, O; Di Cristina, A; Grimaudo, S; Hamel, E; Preti, D; Romagnoli, R; Sarkar, T; Tolomeo, M; Zonta, N | 1 |
| Balzarini, J; Baraldi, PG; Brognara, E; Cruz-Lopez, O; Gambari, R; Hamel, E; Pavani, MG; Romagnoli, R; Zuccato, C | 1 |
| Bastow, KF; Goto, M; Hamel, E; Kozaka, T; Lai, CY; Lee, KH; Nakagawa-Goto, K; Ohkoshi, E; Wu, PC; Zhang, L; Zhu, H | 1 |
| Cao, R; Huang, N; Liu, M; Liu, Q; Wang, Y; Yin, M | 1 |
| Abdayem, R; Barret, R; Colomb, E; Dubois, J; Guillaume, J; Haftek, M; Lomberget, T; Nachtergaele, L; Nguyen, TT; Thoret, S; Tran, NC | 1 |
| Aghazadeh Tabrizi, M; Baraldi, PG; Bassetto, M; Basso, G; Bortolozzi, R; Brancale, A; Castagliuolo, I; Hamel, E; Kimatrai Salvador, M; Preti, D; Romagnoli, R; Viola, G | 1 |
| Gu, HW; Guo, J; Huang, SC; Kong, WY; Lin, HY; Qi, JL; Shi, J; Wang, XM; Yang, RW; Yang, YH | 1 |
| Aghazadeh Tabrizi, M; Balzarini, J; Baraldi, PG; Bassetto, M; Basso, G; Bortolozzi, R; Brancale, A; Fu, XH; Gao, Y; Hamel, E; Li, J; Lopez-Cara, C; Preti, D; Romagnoli, R; Viola, G; Zhang, SZ | 1 |
| Liu-Bryan, R; Terkeltaub, R; Viollet, B; Wang, Y | 1 |
| Crooks, PA; Penthala, NR; Thakkar, S | 1 |
| Forgione, P; Husser, MC; Jaunky, DB; Larocque, K; Liu, JT; Piekny, A | 1 |
1 review(s) available for thiophenes and colchicine
| Article | Year |
|---|---|
[Raney-nickel hydrogenolysis. Mechanism and pharmaceutical-chemical use].
Topics: Adenine; Benzene; Biotin; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Colchicine; Glycosides; Halogens; Hydantoins; Indicators and Reagents; Nickel; Nucleosides; Penicillin G; Pharmacopoeias as Topic; Steroids; Strychnine; Sulfonamides; Sulfones; Thiophenes | 1970 |
20 other study(ies) available for thiophenes and colchicine
| Article | Year |
|---|---|
The regulation of male fertility: the state of the art and future possibilities.
Topics: Acetamides; Alkylating Agents; Androgens; Antispermatogenic Agents; Cell Division; Chloramines; Colchicine; Estrogens; Fertility; Fluorine; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Hypothalamus; Male; Nitrofurans; Nitroimidazoles; Progestins; Spermatogenesis; Spermatozoa; Testis; Testosterone; Thiophenes; Vasectomy | 1974 |
Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
Topics: Antineoplastic Agents; Biopolymers; Colchicine; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Models, Molecular; Naphthyridines; Structure-Activity Relationship; Thiophenes; Tubulin; Tumor Cells, Cultured | 1999 |
A novel palladium-mediated coupling approach to 2,3-disubstituted benzo(b)thiophenes and its application to the synthesis of tubulin binding agents.
Topics: Antineoplastic Agents; Catalysis; Colchicine; Humans; Palladium; Protein Binding; Structure-Activity Relationship; Thiophenes; Tubulin; Tumor Cells, Cultured | 2001 |
The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4.
Topics: Antineoplastic Agents; Breast Neoplasms; Colchicine; Drug Screening Assays, Antitumor; Guaiacol; Humans; Stilbenes; Structure-Activity Relationship; Thiophenes; Tubulin; Tumor Cells, Cultured | 2001 |
Novel combretastatin analogues endowed with antitumor activity.
Topics: Animals; Antineoplastic Agents; Benzofurans; Bibenzyls; Binding, Competitive; Biopolymers; Cell Line, Tumor; Cell Nucleus; Colchicine; Endothelial Cells; Endothelium, Vascular; Female; Humans; Mice; Mice, Nude; Microtubules; Organophosphates; Prodrugs; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Thiophenes; Tubulin; Xenograft Model Antitumor Assays | 2006 |
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Humans; Mice; Models, Molecular; Protein Binding; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2006 |
9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cell Survival; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia P388; Mice; Molecular Structure; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 2006 |
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Topics: Animals; Antimitotic Agents; Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Humans; Mice; Protein Binding; Radioligand Assay; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2007 |
Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Anthracenes; Cell Cycle; Cell Line, Tumor; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthalenes; Nocodazole; Podophyllotoxin; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2007 |
Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Topics: Animals; Antineoplastic Agents; Binding Sites; Brain; Cattle; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Chalcones; Colchicine; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; G2 Phase; HeLa Cells; Humans; K562 Cells; Mice; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2008 |
Synthesis and cellular pharmacology studies of a series of 2-amino-3-aroyl-4-substituted thiophene derivatives.
Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; Humans; Mice; Models, Molecular; Rats; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2010 |
Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromones; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthalenes; Protein Binding; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2011 |
Discovery of novel tubulin inhibitors via structure-based hierarchical virtual screening.
Topics: Algorithms; Benzamides; Binding Sites; Colchicine; Crystallography, X-Ray; Drug Discovery; High-Throughput Screening Assays; Humans; Ligands; Molecular Docking Simulation; Polymerization; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship; Thermodynamics; Thiophenes; Tubulin; Tubulin Modulators; User-Computer Interface | 2012 |
Synthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4.
Topics: Antimitotic Agents; Benzofurans; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Heterocyclic Compounds; Humans; Indoles; Microscopy, Confocal; Microtubules; Stereoisomerism; Stilbenes; Thiophenes | 2012 |
Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lymphocytes; Mice; Mitochondria; Models, Molecular; Protein Multimerization; Protein Structure, Quaternary; Pyridines; Thiophenes; Tubulin; Xenograft Model Antitumor Assays | 2013 |
Synthesis and biological evaluation of heterocyclic carboxylic acyl shikonin derivatives.
Topics: Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Colchicine; HeLa Cells; Humans; Indoles; Molecular Docking Simulation; Naphthoquinones; Protein Structure, Tertiary; Thiophenes; Tubulin; Tubulin Modulators | 2014 |
Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.
Topics: Animals; Antimitotic Agents; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Colchicine; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mitochondria; Models, Molecular; Protein Multimerization; Protein Structure, Quaternary; Proto-Oncogene Proteins c-bcl-2; Thiophenes; Tubulin; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays | 2013 |
AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages.
Topics: AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cells, Cultured; Colchicine; Enzyme Activation; Gout; Gout Suppressants; Macrophages; Mice, Knockout; Phosphorylation; Pyrones; Thiophenes; Uric Acid | 2016 |
Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
Topics: Antineoplastic Agents; Benzofurans; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Resveratrol; Stilbenes; Thiophenes; Tubulin | 2015 |
Characterization of a recently synthesized microtubule-targeting compound that disrupts mitotic spindle poles in human cells.
Topics: Cell Line, Tumor; Cells, Cultured; Colchicine; Humans; Isoquinolines; Microtubules; Mitosis; Spindle Apparatus; Spindle Poles; Thiophenes | 2021 |