thiophenes has been researched along with ci 972 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conroy, MC; Dong, MK; Gilbertsen, RB; Josyula, U; Sircar, JC; Wilburn, DJ; Wu, WS | 1 |
| Bennett, MK; Cetenko, WJ; Dong, MK; Gilbertsen, RB; Kostlan, CR; Sircar, JC | 1 |
| Conroy, MC; Dong, MK; Gilbertsen, RB; Kossarek, LM; Kostlan, CR; Sircar, JC; Wilburn, DJ | 1 |
| Cetenko, WA; Dong, MK; Gilbertsen, RB; Kostlan, CR; Sircar, JC | 1 |
| Conroy, MC; Dong, MK; Gilbertsen, RB; Kossarek, LM; Kostlan, CR; Sircar, JC | 1 |
| Boehncke, WH; Gilbertsen, RB; Hemmer, J; Sterry, W | 1 |
| Dong, MK; Gilbertsen, RB; Wilburn, DJ | 1 |
| Dong, MK; Gilbertsen, RB | 1 |
| Conroy, MC; Dong, MK; Gilbertsen, RB; Josyula, U; Sircar, JC; Wilburn, DJ | 1 |
9 other study(ies) available for thiophenes and ci 972
| Article | Year |
|---|---|
Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955.
Topics: Animals; Cell Line; Deoxyguanine Nucleotides; Dose-Response Relationship, Drug; Guanine; Guanosine; Humans; Inosine; Male; Purine-Nucleoside Phosphorylase; Pyrimidines; Rats; Rats, Inbred Strains; T-Lymphocytes; Thiophenes | 1992 |
Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th
Topics: B-Lymphocytes; Erythrocytes; Humans; Immunosuppressive Agents; Kinetics; Purine-Nucleoside Phosphorylase; Pyrimidines; T-Lymphocytes; Thiophenes | 1992 |
Biochemical and pharmacological properties of CI-972, a novel 9-deazaguanine analog purine nucleoside phosphorylase (PNP) inhibitor.
Topics: Animals; Cell Line; Cells, Cultured; Deoxyguanine Nucleotides; Guanosine Triphosphate; Humans; Lymphocytes; Male; Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidines; Rats; Rats, Inbred Strains; Thiophenes; Thymidine | 1991 |
Pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase (PNP) inhibitors as potential T-cell selective immunosuppressive agents.
Topics: Cell Line; Erythrocytes; Guanine; Humans; Immunosuppressive Agents; Kinetics; Purine-Nucleoside Phosphorylase; Pyrimidines; Structure-Activity Relationship; T-Lymphocytes; Thiophenes | 1991 |
Selective in vitro inhibition of human MOLT-4 T lymphoblasts by the novel purine nucleoside phosphorylase inhibitor, CI-972.
Topics: Adenine; Cell Division; Deoxycytidine; Deoxyguanine Nucleotides; DNA Replication; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine-Nucleoside Phosphorylase; Pyrimidines; T-Lymphocytes; Thiophenes | 1991 |
Evidence for a pathway independent from 2'-deoxyguanosine and reversible by IL-2 by which purine nucleoside phosphorylase inhibitors block T-cell proliferation.
Topics: Cell Cycle; Cell Line; Deoxyguanosine; Flow Cytometry; Guanine; Humans; Interleukin-2; Interleukin-7; Lymphocyte Activation; Mycosis Fungoides; Purine-Nucleoside Phosphorylase; Pyrimidines; S Phase; Sezary Syndrome; T-Lymphocytes; Thiophenes; Time Factors | 1994 |
PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. I. Suppression of the human mixed lymphocyte reaction (MLR).
Topics: Cells, Cultured; Guanine; Humans; Immunosuppressive Agents; Lymphocyte Culture Test, Mixed; Purine-Nucleoside Phosphorylase; Pyrimidines; T-Lymphocytes; Thiophenes | 1993 |
PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. II. Effects on nucleoside catabolism in human and rat blood in vitro.
Topics: Animals; Chromatography, High Pressure Liquid; Deoxyguanosine; Guanine; Half-Life; Humans; Immunosuppressive Agents; Purine-Nucleoside Phosphorylase; Pyrimidines; Rats; Thiophenes | 1993 |
Activities of two 9-deazaguanine analogue inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955, in vitro and in vivo.
Topics: Animals; Cell Division; Deoxyguanine Nucleotides; Dose-Response Relationship, Drug; Guanine; Humans; Immunosuppressive Agents; Purine-Nucleoside Phosphorylase; Pyrimidines; Rats; Thiophenes; Tumor Cells, Cultured | 1993 |