Page last updated: 2024-08-18

thiophenes and ci 959

thiophenes has been researched along with ci 959 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's13 (92.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boucher, DM; Burke, SE; Dodd, GD; Kaplan, HR; Potoczak, RE; Taylor, DG; Wright, CD1
Aker, KA; Conroy, MC; Devall, LJ; Thueson, DO; Wright, CD1
Adolphson, RL; Cetenko, WA; Connor, DT; Kennedy, JA; Mullican, MD; Sorenson, RJ; Thueson, DO; Unangst, PC; Weikert, RJ; Wright, CD1
Adolphson, RL; Conroy, MC; Schellenberg, RR; Thueson, DO1
Conroy, MC; Dong, MK; Gilbertsen, RB; Wilburn, DJ1
Aker, DO; Conroy, MC; Devall, LJ; Thueson, DO; Wright, CD1
Hedstrom, OR; Kerkvliet, NI; Koller, LD; Steppan, LG; Thueson, DO; Voller, BE1
Conroy, MC; Finkel, M; Grabow, D; Lesch, M; Low, J; Metz, A; Schrier, D; Sommers, C; Wallace, J1
Henry, SP; Knowlton, P; Loewen, G; Low, JE; Mertz, TE; Metz, AL; Olszewski, BJ; Robertson, DG; Schroeder, RL; Sommers, CS1
Bleavins, MR; de la Iglesia, FA; McCay, JA; Munson, AE; White, KL1
Conroy, MC; Devall, LJ; Ferin, MA; Hoffman, MD; Kennedy, JA; Kuipers, PJ; Stewart, SF; Thueson, DO; Wright, CD1
Boschelli, DH; Connor, DT; Ferin, MA; Kramer, JB; Lesch, ME; Schrier, DJ; Wright, CD1
Keller, H; Porzig, H; von Tscharner Biino, N1
Azuma, M; Baba, M; Izumo, S; Makino, M; Suruga, Y; Wakamatsu, SI; Yokoyama, MM1

Other Studies

14 other study(ies) available for thiophenes and ci 959

ArticleYear
Reduction of canine myocardial infarct size by CI-959, an inhibitor of inflammatory cell activation.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coronary Circulation; Dogs; Free Radicals; Hemodynamics; In Vitro Techniques; Inflammation; Male; Myocardial Infarction; Myocardium; Neutrophils; Phagocytosis; Tetrazoles; Thiophenes; Ventricular Fibrillation

1992
Differential regulation of human eosinophil, macrophage, and neutrophil functions by the allergic mediator release inhibitor CI-959.
    Agents and actions, 1992, Volume: 36, Issue:1-2

    Topics: Down-Regulation; Enzyme Inhibitors; Eosinophils; Free Radicals; Humans; In Vitro Techniques; Lysosomes; Macrophages; Neutrophils; Oxygen Consumption; Respiratory Burst; Superoxides; Tetrazoles; Thiophenes

1992
Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.
    Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5

    Topics: Antibodies, Anti-Idiotypic; Basophils; Benzofurans; Eosinophils; Histamine Antagonists; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; Lung; Molecular Structure; Naphthalenes; Neutrophils; Respiratory Burst; Structure-Activity Relationship; Tetrazoles; Thiophenes

1992
CI-959, a new, potential antiallergic drug, inhibits mediator release from lung and contractions of human airways in vitro.
    International archives of allergy and applied immunology, 1990, Volume: 93, Issue:2-3

    Topics: Animals; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; Histamine Release; Humans; Immunoglobulin E; Leukotrienes; Lung; Tetrazoles; Thiophenes; Thromboxanes

1990
Inhibition of interleukin-2 production and lymphocyte responsiveness by the cell activation inhibitor, CI-959.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Concanavalin A; Depression, Chemical; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Mitogens; Phytohemagglutinins; Rats; Tetrazoles; Thiophenes

1991
Differential regulation of the activation of human eosinophils, macrophages, and neutrophils: effect of the allergic mediator release inhibitor CI-949.
    Agents and actions, 1990, Volume: 31, Issue:1-2

    Topics: Acetylglucosaminidase; Enzyme Inhibitors; Eosinophils; Humans; In Vitro Techniques; Lysosomes; Macrophage Activation; Macrophages; Neutrophils; Oxygen Consumption; Peroxidase; Superoxides; Tetrazoles; Thiophenes; Zymosan

1990
Effect of CI-949 and CI-959 on immune function and lymphoid organs in rats.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:5

    Topics: Animals; Antibody Formation; Azoles; Body Weight; Cytotoxicity Tests, Immunologic; Enzyme-Linked Immunosorbent Assay; Hypersensitivity; Hypersensitivity, Delayed; Immunity; Immunity, Cellular; Indoles; Killer Cells, Natural; Lymphocytes; Male; Rats; Rats, Inbred Strains; Spleen; Tetrazoles; Thiophenes; Thymus Gland

1989
Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cell Adhesion; Dinoprostone; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Indomethacin; Leukocytes; Leukotriene C4; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfhydryl Compounds; Tetrazoles; Thiophenes

1995
Cardiac hypertrophy in rats after intravenous administration of CI-959, a novel antiinflammatory compound: morphologic features and pharmacokinetic and pharmacodynamic mechanisms.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiomegaly; Catecholamines; Cells, Cultured; Creatine Kinase; Disease Models, Animal; Glycogen; Heart; Heart Rate; Infusion Pumps, Implantable; Infusions, Intravenous; L-Lactate Dehydrogenase; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tetrazoles; Thiophenes

1995
Immunotoxicologic studies with CI-959, a novel benzothiophene cell activation inhibitor.
    Toxicology, 1995, Apr-12, Volume: 98, Issue:1-3

    Topics: Animals; Antibody Formation; B-Lymphocytes; Female; Immunity; Killer Cells, Natural; Listeria monocytogenes; Lymphocyte Activation; Male; Melanoma, Experimental; Mice; Mononuclear Phagocyte System; Rats; Rats, Inbred F344; Streptococcus pneumoniae; T-Lymphocytes; Tetrazoles; Thiophenes

1995
Selective regulation of human neutrophil functions by the cell activation inhibitor CI-959.
    Journal of leukocyte biology, 1994, Volume: 55, Issue:4

    Topics: Arachidonic Acid; Calcium; Calmodulin; Humans; Lysosomes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pentose Phosphate Pathway; Phospholipases; Protein Kinase C; Respiratory Burst; Superoxides; Tetrazoles; Thiophenes

1994
3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion.
    Journal of medicinal chemistry, 1994, Mar-18, Volume: 37, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Endothelium, Vascular; Humans; Neutrophils; Rats; Structure-Activity Relationship; Tetrazoles; Thiophenes

1994
Suppression of polarity, locomotion and F-actin levels of Walker carcinosarcoma cells by the inhibitor CI-959.
    Life sciences, 1997, Volume: 61, Issue:2

    Topics: Actins; Animals; Calcium; Carcinoma 256, Walker; Cell Movement; Cell Polarity; Dose-Response Relationship, Drug; Tetrazoles; Thiophenes; Tumor Cells, Cultured

1997
Marked suppression of T cells by a benzothiophene derivative in patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
    Clinical and diagnostic laboratory immunology, 1999, Volume: 6, Issue:3

    Topics: Adult; Aged; Antigen-Presenting Cells; Antigens, CD; B7-2 Antigen; Cell Differentiation; Cell Survival; Cells, Cultured; Dendritic Cells; Female; Human T-lymphotropic virus 1; Humans; Intercellular Adhesion Molecule-1; Lymphocyte Activation; Male; Membrane Glycoproteins; Middle Aged; Paraparesis, Tropical Spastic; T-Lymphocytes; Tetrazoles; Thiophenes; Tumor Cells, Cultured

1999