thiophenes has been researched along with bw 723c86 in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (17.02) | 18.2507 |
| 2000's | 22 (46.81) | 29.6817 |
| 2010's | 15 (31.91) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Baxter, GS; Byrne, C; Ellis, ES; Murphy, OE; Tilford, NS | 1 |
| Baxter, GS; Blackburn, TP; Bright, F; Kennett, GA; Trail, B | 1 |
| Ainsworth, K; Blackburn, TP; Kennett, GA; Trail, B | 1 |
| Lavielle, G; Millan, MJ; Peglion, JL; Perrin-Monneyron, S | 1 |
| Blackburn, T; Kennett, G; Middlemiss, D; Stean, T; Upton, N | 1 |
| Bright, F; Kennett, GA; Trail, B | 1 |
| Fink, GD; Watts, SW | 1 |
| Dekeyne, A; Girardon, S; Millan, MJ | 1 |
| Knowles, ID; Ramage, AG | 1 |
| Glusa, E; Pertz, HH | 1 |
| Jordan, D; Sévoz-Couche, C; Spyer, KM | 1 |
| Asmussen, M; de Vry, J; Hesse, D; Schreiber, R; Selbach, K | 1 |
| Martin, GR; Martin, RS | 1 |
| Fone, KC; Topham, IA | 1 |
| Watts, SW | 1 |
| Bourin, M; Hascoët, M; Nic Dhonnchadha, BA | 1 |
| Cunningham, KA; Filip, M; McCreary, AC | 1 |
| Banes, AK; Watts, SW | 1 |
| Goto, F; Obata, H; Saito, S; Sakurazawa, S; Sasaki, M; Usui, T | 1 |
| Calama, E; Martín, ML; Morán, A; Ortiz de Urbina, AV; San Román, L | 1 |
| Bubar, MJ; Cunningham, KA; Filip, M | 1 |
| Bourin, M; Hascoët, M; Ripoll, N | 1 |
| Günther, S; Maroteaux, L; Schwarzacher, SW | 1 |
| Bourin, M; Hascoët, M; Massé, F; Nic Dhonnchadha, BA | 1 |
| Bernard, JF; Comet, MA; Hamon, M; Laguzzi, R; Sévoz-Couche, C | 1 |
| Distad, M; Farrugia, G; Gibbons, SJ; Ou, Y; Roeder, JL; Strege, PR; Szurszewski, JH; Wouters, MM | 1 |
| Cheng, Q; Dergacheva, O; Gorini, C; Jameson, H; Kamendi, H; Mendelowitz, D; Pinol, RM; Wang, X | 1 |
| Asaka, M; Hattori, T; Katsurada, T; Nagai, K; Ohkawara, T; Sadakane, C; Takeda, H | 1 |
| Anwyl, R; Rowan, MJ; Ryan, BK | 1 |
| Bardsley, MR; Farrugia, G; Gibbons, SJ; Lei, S; Ordog, T; Roeder, JL; Stanich, JE; Strege, PR; Tharayil, VS; Wouters, MM | 1 |
| Baumann, MH; Blough, BE; Jacobson, AE; Partilla, JS; Rice, KC; Rothman, RB | 1 |
| MacFarlane, PM; Mitchell, GS; Vinit, S | 1 |
| Berson, N; Conrath, M; Doly, S; Maroteaux, L; Pohl, M; Truchetto, J; Urtikova, N; Van Steenwinckel, J | 1 |
| Aldegunde, M; Mancebo, MJ; Pérez-Maceira, JJ | 1 |
| Fang, X; Fung, ML; Huang, Y; Liu, Y; Mao, G; Shyy, JY; Tian, XY; Wang, N | 1 |
| Aira, Z; Azkue, JJ; Bilbao, J; Buesa, I; Doñate, F; García Del Caño, G; Zimmermann, M | 1 |
| Gwarek, M; Lübbert, H; Schmitz, B; Segelcke, D; Ullmer, C; Zhu, XR | 1 |
| Kimura, M; Mitsuhashi, M; Moteki, H; Naito, K; Natsume, H; Ogihara, M; Tanaka, C | 1 |
| Kimura, M; Moteki, H; Naito, K; Natsume, H; Ogihara, M | 1 |
| Avdonin, PV; Goncharov, NV; Kudryavtsev, IV; Nadeev, AD; Serebriakova, MK; Zinchenko, VP | 1 |
| Chang, SE; Hwang, JS; Kim, SY; Lee, JE; Myung, CH; Oh, EJ; Park, JI | 1 |
| Avdonin, PP; Avdonin, PV; Goncharov, NV; Jenkins, RO; Mironova, GY | 1 |
| Bravo Sagua, R; Busso, D; Cárdenas, C; Cataldo, LR; Cortés, VA; Galgani, JE; Jaña, F; Llanos, P; Mizgier, ML; Olmos, P; Santos, JL | 1 |
| Banas, SM; Belmer, A; Diaz, SL; Doly, S; Fernandez, SP; Guiard, BP; Mameli, M; Maroteaux, L; Moutkine, I; Muzerelle, A; Pitychoutis, PM; Quentin, E; Roumier, A; Tchenio, A | 1 |
| Avdonin, PP; Avdonin, PV; Goncharov, NV; Mironova, GY; Nadeev, AD; Zharkikh, IL | 1 |
| Clemmensen, B; Gould, TW; Ha, SE; Heredia, DJ; Jin, B; Ro, S; Sanders, KM; Singh, R; Wei, L; Zogg, H | 1 |
| Arnoux, A; Ayme-Dietrich, E; Dieterle, S; Dupuis, L; Frauli, M; Goy, MA; Monassier, L; Schann, S | 1 |
47 other study(ies) available for thiophenes and bw 723c86
| Article | Year |
|---|---|
Mediation by 5-hydroxytryptamine2B receptors of endothelium-dependent relaxation in rat jugular vein.
Topics: Animals; Carbachol; Endothelium, Vascular; In Vitro Techniques; Indoles; Jugular Veins; Male; Mianserin; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes; Urea; Yohimbine | 1995 |
Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Disease Models, Animal; Indoles; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Thiophenes; Urea | 1996 |
BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats.
Topics: Animals; Eating; Grooming; Humans; Hyperphagia; Indoles; Injections, Intraventricular; Injections, Subcutaneous; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1997 |
5-HT2C receptors mediate penile erections in rats: actions of novel and selective agonists and antagonists.
Topics: Animals; Dose-Response Relationship, Drug; Ethylamines; Indoles; Male; Penile Erection; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes; Urea | 1997 |
Studies on the role of 5-HT2C and 5-HT2B receptors in regulating generalised seizure threshold in rodents.
Topics: Animals; Drug Interactions; Electric Stimulation; Indoles; Male; Mice; Pentylenetetrazole; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Seizures; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1998 |
Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Conditioning, Operant; Conflict, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1998 |
5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Gastric Fundus; Gastrointestinal Motility; Hypertension; Indoles; Male; Mesenteric Arteries; Organic Chemicals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Chloride; Thiophenes; Time Factors; Vasoconstriction | 1999 |
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1999 |
Evidence that activation of central 5-HT(2B) receptors causes renal sympathoexcitation in anaesthetized rats.
Topics: Amidines; Anesthesia; Animals; Blood Pressure; Heart Rate; Indoles; Injections, Intraventricular; Ketanserin; Kidney; Male; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Stimulation, Chemical; Sulfonamides; Sympathetic Nervous System; Thiophenes | 2000 |
Further evidence that 5-HT-induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT(2B) receptors.
Topics: Animals; Endothelium, Vascular; In Vitro Techniques; Indoles; Muscle Relaxation; Muscle, Smooth, Vascular; Pulmonary Artery; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swine; Thiophenes | 2000 |
In vivo modulation of vagal-identified dorsal medullary neurones by activation of different 5-Hydroxytryptamine(2) receptors in rats.
Topics: Afferent Pathways; Amphetamines; Animals; Antihypertensive Agents; Electric Conductivity; Evoked Potentials; Heart; Indoles; Lung; Male; Medulla Oblongata; Nerve Fibers, Myelinated; Neurons; Organic Chemicals; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Spiro Compounds; Sulfonamides; Thiophenes; Vagus Nerve | 2000 |
Effects of serotonin(1/2) receptor agonists on dark-phase food and water intake in rats.
Topics: Amphetamines; Animals; Darkness; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Eating; Feeding Behavior; Female; Indoles; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiophenes; Time Factors | 2000 |
Investigations into migraine pathogenesis: time course for effects of m-CPP, BW723C86 or glyceryl trinitrate on appearance of Fos-like immunoreactivity in rat trigeminal nucleus caudalis (TNC).
Topics: Animals; Genes, fos; Indoles; Migraine Disorders; Nitric Oxide; Nitroglycerin; Piperazines; Rats; Serotonin Receptor Agonists; Thiophenes; Time Factors; Trigeminal Caudal Nucleus; Vasodilator Agents | 2001 |
Alteration in 5-hydroxytryptamine agonist-induced behaviour following a corticosterone implant in adult rats.
Topics: Amphetamines; Animals; Behavior, Animal; Blood Glucose; Body Temperature; Brain Chemistry; Corticosterone; Drug Implants; Eating; Indoles; Male; Motor Activity; Piperazines; Rats; Serotonin Receptor Agonists; Thiophenes | 2002 |
Serotonin-induced contraction in mesenteric resistance arteries: signaling and changes in deoxycorticosterone acetate-salt hypertension.
Topics: Animals; Carbazoles; Desoxycorticosterone; Dose-Response Relationship, Drug; Fluorobenzenes; Hypertension; In Vitro Techniques; Indoles; Ketanserin; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Sumatriptan; Thiophenes; Vascular Resistance; Vasoconstriction | 2002 |
Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety.
Topics: Amphetamines; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylamines; Indoles; Ketanserin; Male; Maze Learning; Mice; Motor Activity; Naphthyridines; Piperazine; Piperazines; Psychomotor Performance; Pyridines; Reaction Time; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Thiophenes | 2003 |
Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Fenfluramine; Fluorobenzenes; Indoles; Ketanserin; Male; Piperidines; Pyrazines; Pyridines; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Thiophenes | 2003 |
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension.
Topics: Animals; Arteries; Desoxycorticosterone; Female; Gene Expression; Hypertension; Indoles; Male; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Chloride; Thiophenes; Vasoconstriction | 2003 |
Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury.
Topics: Amphetamines; Animals; Indoles; Injections, Spinal; Ketanserin; Ligation; Lumbar Vertebrae; Male; Neuralgia; Nociceptors; Piperazines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Nerves; Spiro Compounds; Sulfonamides; Thiophenes | 2004 |
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Indoles; Injections, Intra-Arterial; Injections, Intravenous; Male; Perfusion; Piperazines; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spiperone; Thiophenes; Vasoconstriction | 2004 |
Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses.
Topics: Amphetamines; Animals; Cocaine; Drug Interactions; Fluorobenzenes; Hyperkinesis; Indoles; Male; Phenols; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 2004 |
Implication of 5-HT2A subtype receptors in DOI activity in the four-plates test-retest paradigm in mice.
Topics: Amphetamines; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Mice; Protein Subunits; Receptors, Serotonin; Reproducibility of Results; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Thiophenes | 2006 |
Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro.
Topics: Animals; Animals, Newborn; In Vitro Techniques; Indoles; Ketanserin; Kinetics; Mice; Microinjections; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Respiration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2006 |
Anxiolytic-like effect of 5-HT(2) ligands and benzodiazepines co-administration: comparison of two animal models of anxiety (the four-plate test and the elevated plus maze).
Topics: Amphetamines; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Indoles; Male; Maze Learning; Mice; Serotonin Receptor Agonists; Thiophenes | 2007 |
Activation of nucleus tractus solitarius 5-HT2A but not other 5-HT2 receptor subtypes inhibits the sympathetic activity in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine Derivatives; Baroreflex; Blood Pressure; Heart Rate; Indoles; Male; Microinjections; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Thiophenes | 2007 |
Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors.
Topics: Animals; Cell Proliferation; Cell Survival; Coculture Techniques; Indoles; Jejunum; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Myocytes, Smooth Muscle; Receptor, Serotonin, 5-HT2B; Ritanserin; RNA, Messenger; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Thiophenes; Urea | 2007 |
5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus.
Topics: Action Potentials; Animals; Animals, Newborn; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indoles; Neurons; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes; Vagus Nerve | 2008 |
Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.
Topics: Acylation; Aminopyridines; Animals; Anorexia; Antineoplastic Agents; Body Weight; Chalcones; Cisplatin; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Eating; Flavones; Gastric Mucosa; Gastrointestinal Agents; Ghrelin; Hesperidin; Indoles; Male; Oligopeptides; Piperazines; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Ghrelin; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Stomach; Thiophenes; Vagotomy | 2008 |
5-HT2 receptor-mediated reversal of the inhibition of hippocampal long-term potentiation by acute inescapable stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cinanserin; Disease Models, Animal; Dose-Response Relationship, Radiation; Drug Administration Routes; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Fenfluramine; Hippocampus; Indoles; Long-Term Potentiation; Male; Neural Inhibition; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Restraint, Physical; Serotonin Agents; Stress, Psychological; Thiophenes | 2008 |
Protein kinase C{gamma} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B.
Topics: Animals; Chromones; Coiled Bodies; Enzyme Inhibitors; Estrenes; Fibroblasts; Indoles; Macrocyclic Compounds; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Pyrrolidinones; Receptor, Serotonin, 5-HT2B; Thiophenes | 2009 |
Evidence for noncompetitive modulation of substrate-induced serotonin release.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Indoles; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Synaptosomes; Thiophenes; Time Factors; Tritium | 2010 |
Serotonin 2A and 2B receptor-induced phrenic motor facilitation: differential requirement for spinal NADPH oxidase activity.
Topics: Acetophenones; Action Potentials; Amphetamines; Animals; Indoles; Injections, Spinal; Ketanserin; Male; NADPH Oxidases; Onium Compounds; Phrenic Nerve; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2011 |
Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.
Topics: Animals; Disease Models, Animal; Ganglia, Spinal; Indoles; Male; Neuralgia; Nociceptors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Sciatic Nerve; Sciatic Neuropathy; Serotonin; Serotonin 5-HT2 Receptor Agonists; Thiophenes | 2012 |
Serotonin-induced brain glycogenolysis in rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Benzopyrans; Brain; Glycogen; Glycogen Phosphorylase, Brain Form; Glycogenolysis; Indoles; Injections, Intraperitoneal; Injections, Intraventricular; Morpholines; Oncorhynchus mykiss; Piperazines; Pyrazines; Pyridines; Quinoxalines; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Thiophenes; Time Factors | 2012 |
Peroxisome proliferator-activated receptor-γ ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor.
Topics: Animals; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypoxia; Indoles; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Pulmonary Artery; Receptor, Serotonin, 5-HT2B; Rosiglitazone; Serotonin 5-HT2 Receptor Agonists; Thiazolidinediones; Thiophenes; Transcription Factor AP-1; Up-Regulation | 2012 |
Transient, 5-HT2B receptor-mediated facilitation in neuropathic pain: Up-regulation of PKCγ and engagement of the NMDA receptor in dorsal horn neurons.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Hyperalgesia; Indoles; Male; Nerve Fibers, Unmyelinated; Neuralgia; Neurons; Physical Stimulation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists; Spinal Nerve Roots; Spinal Nerves; Subcellular Fractions; Thiophenes; Time Factors; Up-Regulation | 2013 |
BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs.
Topics: Animals; Blood Proteins; Brain; Cell Line; Guinea Pigs; Humans; Indoles; Male; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Substrate Specificity; Thiophenes; Thioxanthenes; Xanthenes | 2015 |
Signal Transduction Mechanism for Serotonin 5-HT2B Receptor-Mediated DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes.
Topics: Animals; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hepatocytes; Indoles; Phosphorylation; Rats; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Thiophenes | 2016 |
Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-α in Primary Cultures of Adult Rat Hepatocytes.
Topics: Animals; Cell Proliferation; Cells, Cultured; DNA; Estrenes; Hepatocytes; Indoles; Male; Organic Chemicals; Pyrrolidinones; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes; Transforming Growth Factor alpha; Type C Phospholipases | 2016 |
[DUAL PROAPOPTOTIC AND PRONECROTIC EFFECT OF HYDROGEN PEROXIDE ON HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS].
Topics: Anthracyclines; Antigens, CD; Apoptosis; Benzoxazoles; Biomarkers; Calcium; Calcium Channel Agonists; Cell Count; Cell Survival; Dose-Response Relationship, Drug; Factor VIII; Flow Cytometry; Fluorescent Dyes; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Necrosis; Peptidyl-Dipeptidase A; Receptors, Serotonin; Thiophenes | 2015 |
A Novel Role of Serotonin Receptor 2B Agonist as an Anti-Melanogenesis Agent.
Topics: Animals; Cell Line; Down-Regulation; Humans; Indoles; Melanins; Melanocytes; Mice; Protein-Tyrosine Kinases; Serotonin 5-HT2 Receptor Agonists; Signal Transduction; Thiophenes | 2016 |
Inhibition of protein tyrosine phosphatases unmasks vasoconstriction and potentiates calcium signaling in rat aorta smooth muscle cells in response to an agonist of 5-HT2B receptors BW723C86.
Topics: Animals; Aorta; Calcium Signaling; Cell Separation; Indoles; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oxidative Stress; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Vanadates; Vasoconstriction; Vasoconstrictor Agents | 2017 |
Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Gene Expression Regulation; Glucose; Humans; Indoles; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mitochondria; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Receptors, Serotonin; Serotonin; Thiophenes; Urea | 2017 |
Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Body Temperature; Central Nervous System Sensitization; Female; Fluoxetine; Indoles; Male; Mice; Mice, Knockout; Mice, Transgenic; Neurogenesis; Prepulse Inhibition; Raphe Nuclei; Receptor, Serotonin, 5-HT2B; Serotonergic Neurons; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Transcription Factors | 2018 |
Enhancement by Hydrogen Peroxide of Calcium Signals in Endothelial Cells Induced by 5-HT1B and 5-HT2B Receptor Agonists.
Topics: Acetylcysteine; Benzoxazoles; Calcium; Calcium Signaling; Fluorescence; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Triazoles; Vanadates | 2019 |
Colonic Motility Is Improved by the Activation of 5-HT
Topics: Animals; Calcium Signaling; Colon; Constipation; Diabetes Complications; Disease Models, Animal; Female; Gastrointestinal Motility; Genes, Reporter; Indoles; Interstitial Cells of Cajal; Male; Mice, Inbred C57BL; Mice, Transgenic; Myoelectric Complex, Migrating; Ovariectomy; Proto-Oncogene Proteins c-kit; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Tryptophan Hydroxylase | 2021 |
Evaluation of a 5-HT
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Female; Indoles; Male; Mice; Mice, Transgenic; Microglia; Motor Neurons; Nerve Degeneration; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Agonists; Superoxide Dismutase-1; Thiophenes | 2021 |