Page last updated: 2024-08-18

thiophenes and busulfan

thiophenes has been researched along with busulfan in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Edwards, K; Jones, AR1
Burns, RB; Embree, L; Heggie, JR1
Chien, JY; Dev, R; Gibbs, JP; Murray, G; Risler, L; Slattery, JT1
Gibbs, JP; Slattery, JT; Yang, JS1
Bohnenstengel, F; Hofmann, U; Kroemer, HK; Ritter, CA; Sperker, B1
Dressel, D; Grube, M; Kroemer, HK; Kunert-Keil, C; Ritter, CA; Sperker, B1
ROBERTS, JJ; WARWICK, GP1
Inagaki, K; Iwamura, H; Komatsu, N; Naka, Y; Oda, T; Shinkai, H1
Ansari, M; Gumy-Pause, F; Krajinovic, M; Mangin, P; Staub, C; Théorêt, Y; Uppugunduri, CR; Versace, F1
El-Serafi, I; Hagbjörk, AL; Hassan, M; Hassan, Z; Terelius, Y; Twelkmeyer, B1
Ansari, M; Bittencourt, H; Daali, Y; Diaz, PH; Duval, M; Krajinovic, M; Rezgui, MA; Rousseau, J; Tyagi, AK; Uppugunduri, CR1
Abedi-Valugerdi, M; El-Serafi, I; Hassan, M; Mattsson, J; Moshfegh, A; Naughton, S; Potácová, Z; Saghafian, M; Terelius, Y1

Other Studies

12 other study(ies) available for thiophenes and busulfan

ArticleYear
Studies with alkylating esters. IV. The metabolism of propane-1,3-dimethanesulphonate and its relevance to the mode of action of Myleran.
    Biochemical pharmacology, 1971, Volume: 20, Issue:8

    Topics: 1-Propanol; Acetylcysteine; Animals; Biotransformation; Busulfan; Carbon Isotopes; Chemosterilants; Chromatography, Paper; Esters; In Vitro Techniques; Male; Methane; Mice; Propylene Glycols; Rabbits; Rats; Spermatozoa; Sulfonic Acids; Sulfur; Sulfur Isotopes; Thiophenes

1971
A gas-chromatographic assay method for busulfan with sensitivity for test dose therapeutic monitoring.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Busulfan; Calibration; Chromatography, Gas; Drug Monitoring; Humans; Phenols; Regression Analysis; Reproducibility of Results; Sulfhydryl Compounds; Thiophenes

1995
Age-dependent tetrahydrothiophenium ion formation in young children and adults receiving high-dose busulfan.
    Cancer research, 1997, Dec-15, Volume: 57, Issue:24

    Topics: Absorption; Administration, Oral; Adolescent; Adult; Aging; Antineoplastic Agents, Alkylating; Area Under Curve; Busulfan; Child; Child, Preschool; Computer Simulation; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Transferase; Half-Life; Humans; Infant; Liver; Male; Middle Aged; Thiophenes

1997
Comparison of human liver and small intestinal glutathione S-transferase-catalyzed busulfan conjugation in vitro.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:1

    Topics: Busulfan; Catalysis; Cytosol; Dinitrobenzenes; Glutathione Transferase; Humans; Intestine, Small; Kinetics; Liver; Proteins; Thiophenes

1998
Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Jun-25, Volume: 730, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Busulfan; Calibration; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Kinetics; Liver; Reproducibility of Results; Sensitivity and Specificity; Thiophenes

1999
Overexpression of glutathione S-transferase A1-1 in ECV 304 cells protects against busulfan mediated G2-arrest and induces tissue factor expression.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: Blotting, Western; Busulfan; Cell Cycle; Cell Division; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; G2 Phase; Glutathione Transferase; Humans; Isoenzymes; Plasmids; Thiophenes; Thromboplastin; Time Factors; Transfection

2002
Metabolic and chemical studies of 'myleran': formation of 3-hydroxytetrahydrothiophene-1, 1-dioxide in vivo, and reactions with thiols in vitro.
    Nature, 1959, Oct-24, Volume: 184

    Topics: Busulfan; In Vitro Techniques; Sulfhydryl Compounds; Thiophenes

1959
Induction of megakaryocytopoiesis and thrombocytopoiesis by JTZ-132, a novel small molecule with thrombopoietin mimetic activities.
    Blood, 2004, Jul-01, Volume: 104, Issue:1

    Topics: Animals; Biomimetic Materials; Blood Cell Count; Busulfan; Cell Differentiation; Cell Division; Cell Line, Tumor; Colony-Forming Units Assay; DNA-Binding Proteins; Erythropoietin; Humans; Interleukin-11; Janus Kinase 2; Male; Mice; Mice, Inbred BALB C; Milk Proteins; Oxadiazoles; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Thiophenes; Thrombopoiesis; Thrombopoietin; Trans-Activators; Tyrosine

2004
A novel method for quantification of sulfolane (a metabolite of busulfan) in plasma by gas chromatography-tandem mass spectrometry.
    Analytical and bioanalytical chemistry, 2012, Volume: 404, Issue:6-7

    Topics: Busulfan; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Humans; Immunosuppressive Agents; Male; Tandem Mass Spectrometry; Thiophenes

2012
Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jan-15, Volume: 913-914

    Topics: Busulfan; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Reproducibility of Results; Thiophenes

2013
The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation.
    The pharmacogenomics journal, 2014, Volume: 14, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Busulfan; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infant, Newborn; Male; Polymorphism, Genetic; Thiophenes; Transplantation Conditioning

2014
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Adolescent; Adult; Animals; Busulfan; Child; Child, Preschool; Gene Expression Regulation; Glutathione Transferase; Hematopoietic Stem Cell Transplantation; Humans; Kinetics; Male; Metabolic Networks and Pathways; Metabolome; Mice, Inbred C57BL; Microsomes; Middle Aged; Oxygenases; RNA, Messenger; Substrate Specificity; Thiophenes; Time Factors; Transplantation Conditioning; Voriconazole

2017