Page last updated: 2024-08-18

thiophenes and bortezomib

thiophenes has been researched along with bortezomib in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's9 (75.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Bouley, DM; Denko, NC; Koong, AC; Lust, S; Niwa, M; Offner, F; Olson, M; Papandreou, I; Solow-Cordero, DE; Tam, A; Van Melckebeke, H1
Altun, M; Anderson, KC; Carrasco, R; Chauhan, D; Fulcinniti, M; Hideshima, T; Kessler, BM; Kingsbury, WD; Kodrasov, MP; Kumar, KG; Leach, CA; McDermott, JL; Minvielle, S; Munshi, N; Nicholson, B; Orlowski, R; Richardson, P; Shah, PK; Tian, Z; Weinstock, J; Zhou, B1
Cassidy, J; Hochster, H1
Jeong, J; Lee, KH; Yoo, CG1
Chien, W; Ding, LW; Garg, M; Gery, S; Kitajima, S; Koeffler, PH; Lee, KL; Leong, WZ; Lim, SL; Poellinger, L; Sun, H; Sun, QY; Takao, S; Tan, SZ; Tokatly, I; Torres-Fernandez, LA; Xiao, J1
Chu, SH; Cleeland, CS; Geng, Y; Lee, ES; Lee, YJ; Wang, XS1
Chirgwin, JM; Suvannasankha, A1
Babich, JW; Mairs, RJ; Nixon, C; Rae, C; Tesson, M1
Barbosa-Dantas, RSS; Colleoni, GWB; de Oliveira, MB; Eugenio, AIP; Sanson, LFG1
Arulananda, S; Behren, A; Cebon, J; Dobrovic, A; Evangelista, M; Fairlie, WD; Gunasingh, G; Haass, NK; Harris, TJ; Herold, MJ; Hobbs, C; John, T; Lee, EF; Mariadason, JM; Ramnac, C; Rohrbeck, L; Segal, D; Strasser, A; Tran, S; Zhu, H1
Chim, CS; Wong, KY1
Hanamura, I; Hosokawa, Y; Hyodo, T; Kanasugi, J; Karnan, S; Konishi, H; Lam, VQ; Mizuno, S; Ota, A; Rahman, ML; Takami, A; Tsuzuki, S; Wahiduzzaman, M1

Reviews

3 review(s) available for thiophenes and bortezomib

ArticleYear
New oxaliplatin-based combinations in the treatment of colorectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5 Suppl 3

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Boronic Acids; Bortezomib; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Gefitinib; Humans; Irinotecan; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Pyrazines; Quinazolines; Thiophenes

2003
Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:2

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Carbamazepine; Central Nervous System; Cyclohexanols; Duloxetine Hydrochloride; Epothilones; Humans; Neoplasms; Neuralgia; Oxcarbazepine; Peripheral Nervous System Diseases; Pyrazines; Taxoids; Thalidomide; Thiophenes; Venlafaxine Hydrochloride; Vinca Alkaloids

2015
Role of bone-anabolic agents in the treatment of breast cancer bone metastases.
    Breast cancer research : BCR, 2014, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Boronic Acids; Bortezomib; Breast Neoplasms; Everolimus; Female; Humans; Oligopeptides; Osteoblasts; Parathyroid Hormone; Proteasome Inhibitors; Pyrazines; Recombinant Fusion Proteins; Sirolimus; Thiophenes; Transforming Growth Factor beta

2014

Other Studies

9 other study(ies) available for thiophenes and bortezomib

ArticleYear
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma.
    Blood, 2011, Jan-27, Volume: 117, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cells, Cultured; Cytotoxins; Dose-Response Relationship, Drug; Endoribonucleases; Humans; Mice; Models, Biological; Multiple Myeloma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazines; Substrate Specificity; Sulfonamides; Thiophenes; Xenograft Model Antitumor Assays

2011
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.
    Cancer cell, 2012, Sep-11, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Dexamethasone; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Lenalidomide; Mice; Mice, SCID; Molecular Sequence Data; Multiple Myeloma; Neovascularization, Pathologic; Protease Inhibitors; Proto-Oncogene Proteins c-mdm2; Pyrazines; Random Allocation; Thalidomide; Thiophenes; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7; Xenograft Model Antitumor Assays

2012
Long-term incubation with proteasome inhibitors (PIs) induces IκBα degradation via the lysosomal pathway in an IκB kinase (IKK)-dependent and IKK-independent manner.
    The Journal of biological chemistry, 2013, Nov-08, Volume: 288, Issue:45

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Dipeptides; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-8; Ketones; Leupeptins; Lysosomes; Microtubule-Associated Proteins; Mutation, Missense; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Inhibitors; Proteolysis; Pyrazines; Thiophenes; Time Factors

2013
Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.
    Oncotarget, 2014, Jul-15, Volume: 5, Issue:13

    Topics: Animals; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; DNA-Binding Proteins; Drug Synergism; Endoribonucleases; Enzyme Inhibitors; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred NOD; Mice, SCID; Naphthalenes; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Pyrazines; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA Splicing; Sulfonamides; Thiophenes; Toyocamycin; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1; Xenograft Model Antitumor Assays

2014
Preliminary evaluation of prostate-targeted radiotherapy using (131) I-MIP-1095 in combination with radiosensitising chemotherapeutic drugs.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Cell Line, Tumor; Cell Proliferation; Disulfiram; Glutamates; Humans; Imidazoles; Iodine Radioisotopes; Male; Molecular Targeted Therapy; Phthalazines; Piperazines; Prostate; Spheroids, Cellular; Thiophenes; Topotecan; Tumor Cells, Cultured; Urea

2016
Stew in its Own Juice: Protein Homeostasis Machinery Inhibition Reduces Cell Viability in Multiple Myeloma Cell Lines.
    Current molecular medicine, 2019, Volume: 19, Issue:2

    Topics: Apoptosis; Autophagy; Benzamides; Bortezomib; Cell Survival; Drug Synergism; HSP70 Heat-Shock Proteins; Humans; Multiple Myeloma; Proteasome Inhibitors; Proteostasis; Pyrimidines; Sulfonamides; Thiophenes; Tumor Cells, Cultured; Unfolded Protein Response

2019
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.
    Cell death & disease, 2019, 04-24, Volume: 10, Issue:5

    Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; bcl-X Protein; Bortezomib; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Myeloid Cell Leukemia Sequence 1 Protein; Pyrimidines; Sulfonamides; Thiophenes

2019
Venetoclax, bortezomib and S63845, an MCL1 inhibitor, in multiple myeloma.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 14; Drug Resistance, Neoplasm; Drug Synergism; Humans; Inhibitory Concentration 50; Multiple Myeloma; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Sulfonamides; Thiophenes; Translocation, Genetic

2020
Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells.
    Cancer science, 2020, Volume: 111, Issue:5

    Topics: Animals; Antineoplastic Agents; Bortezomib; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Mice; Mice, SCID; Multiple Myeloma; Nucleotidyltransferases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; Signal Transduction; Thiophenes

2020