thiophenes has been researched along with b 428 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davidson, DJ; Harakidas, P; Henkin, J; Mazar, AP; Rabbani, SA | 1 |
| Alonso, DF; Bal de Kier Joffé, E; Davel, L; Farías, EF; Ladeda, V; Puricelli, L | 1 |
| Henkin, J; Mazar, A; Rabbani, SA; Xing, RH | 1 |
| Chan, H; Katz, BA; Luong, C; Mackman, R; Martelli, A; Radika, K; Sprengeler, PA; Wang, J; Wong, L | 1 |
| Evans, DM; Sloan-Stakleff, K | 1 |
| Arroyo de Prada, N; Graeff, H; Luther, T; Magdolen, U; Magdolen, V; Muehlenweg, B; Reuning, U; Schmitt, M; Sperl, S; Wilhelm, OG | 1 |
| Butler, C; Dorwin, S; Giranda, VL; Hulkower, KI; Klinghofer, V; McGonigal, T; Nienaber, V; Richardson, P; Rockway, T; Sarthy, A; Smith, R; Stewart, K; Weitzberg, M; Wendt, M; Zhao, X | 1 |
| Carter, KJ; Fingleton, B; Hachey, DL; Matrisian, LM; McIntyre, JO; Menon, R; Overstreet, PD | 1 |
| Bahi, A; Dreyer, JL; Kusnecov, AW | 1 |
| Cheng, CY; Hsieh, HL; Ma, DH; Pang, JH; Sun, CC; Yang, CM; Yu, WH | 1 |
| Al Ameri, M; Al Maamari, E; Al Mansouri, S; Bahi, A | 1 |
1 review(s) available for thiophenes and b 428
| Article | Year |
|---|---|
Natural and synthetic inhibitors of the tumor-associated serine protease urokinase-type plasminogen activator.
Topics: Amidines; Amiloride; Animals; Benzamidines; Guanidines; Mice; Mice, Knockout; Models, Biological; Molecular Structure; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Serine Proteinase Inhibitors; Serpins; Structure-Activity Relationship; Thiophenes; Urokinase-Type Plasminogen Activator | 2000 |
10 other study(ies) available for thiophenes and b 428
| Article | Year |
|---|---|
Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA).
Topics: Amidines; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms; Rats; Thiophenes; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1995 |
Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model.
Topics: Amidines; Amiloride; Animals; Antineoplastic Agents; Cell Division; Diuretics; Enzyme Inhibitors; Female; Fibrinolysis; Fibronectins; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Thiophenes; Triamterene; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1996 |
Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428.
Topics: Amidines; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Drug Screening Assays, Antitumor; Estrogen Antagonists; Female; Neoplasm Invasiveness; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tamoxifen; Thiophenes; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1997 |
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.
Topics: Amidines; Binding Sites; Drug Design; Factor Xa; Glycosylation; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Recombinant Proteins; Serine Proteinase Inhibitors; Substrate Specificity; Thiophenes; Thrombin; Tissue Plasminogen Activator; Trypsin; Urokinase-Type Plasminogen Activator | 2000 |
Suppression of the invasive capacity of human breast cancer cells by inhibition of urokinase plasminogen activator via amiloride and B428.
Topics: Amidines; Amiloride; Breast Neoplasms; Cell Division; Humans; Neoplasm Invasiveness; Serine Proteinase Inhibitors; Thiophenes; Tumor Cells, Cultured | 2000 |
Species specificity of amidine-based urokinase inhibitors.
Topics: Amidines; Amiloride; Amino Acid Sequence; Animals; Antineoplastic Agents; Binding Sites; Blood Proteins; Carcinoma, Lewis Lung; Crystallography, X-Ray; Humans; Mice; Molecular Sequence Data; Naphthalenes; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Species Specificity; Thiophenes; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2001 |
Proteinase activity in human and murine saliva as a biomarker for proteinase inhibitor efficacy.
Topics: Amidines; Amylases; Animals; Biomarkers; Blood Proteins; Chromatography, Liquid; Endopeptidases; Female; Humans; Imidazoles; Male; Mass Spectrometry; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Organic Chemicals; Phenylalanine; Protease Inhibitors; Saliva; Thiophenes; Urokinase-Type Plasminogen Activator | 2004 |
Effects of urokinase-type plasminogen activator in the acquisition, expression and reinstatement of cocaine-induced conditioned-place preference.
Topics: Amidines; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Gene Expression Regulation; Green Fluorescent Proteins; Lentivirus; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reinforcement, Psychology; Thiophenes; Urokinase-Type Plasminogen Activator | 2008 |
Novel laminin 5 gamma 2-chain fragments potentiating the limbal epithelial cell outgrowth on amniotic membrane.
Topics: Amidines; Amnion; Blotting, Western; Cell Movement; Cell Proliferation; Coculture Techniques; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Fibrinolysin; Fluorescent Antibody Technique, Indirect; Humans; Laminin; Limbus Corneae; Matrix Metalloproteinase 9; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiophenes; Up-Regulation; Urokinase-Type Plasminogen Activator | 2009 |
Inhibition of urokinase plasminogen activator "uPA" activity alters ethanol consumption and conditioned place preference in mice.
Topics: Alcohol Drinking; Amidines; Animals; Conditioning, Classical; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Structure-Activity Relationship; Thiophenes; Urokinase-Type Plasminogen Activator | 2014 |