thiophenes has been researched along with arachidonic acid in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (26.92) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowling, N; Hayes, SJ; Ho, PP; Panetta, JA; Pollock, D; Towner, RD; Wang, LY; Wyss, V | 1 |
| Asai, F; Ikeda, T; Ito, T; Matsuda, K; Nakagawa, A; Oshima, T; Terada, A; Ushiyama, S; Yamazaki, M | 1 |
| Hsueh, W; Needleman, P; Spaethe, SM | 1 |
| Cannizzaro, S; Davì, G; Giubilato, A; Strano, A | 1 |
| Aurousseau, M; Benveniste, J; Chignard, M; Greiss, M; Lalau Keraly, C; Maamer, M | 1 |
| Bruno, JJ; Chang, LF; McSpadden, MM; Yang, D | 1 |
| Bonta, IL; vd Veerdonk, MA; Vincent, JE; Zijlstra, FJ | 1 |
| Chevolet, C; Dresse, A; Grosdent, JC; Reiters, GM | 1 |
| Conroy, MC; Finkel, M; Grabow, D; Lesch, M; Low, J; Metz, A; Schrier, D; Sommers, C; Wallace, J | 1 |
| Creely, DP; Gierse, JK; Hauser, SD; Isakson, PC; Koboldt, C; Rangwala, SH; Seibert, K | 1 |
| Conroy, MC; Devall, LJ; Ferin, MA; Hoffman, MD; Kennedy, JA; Kuipers, PJ; Stewart, SF; Thueson, DO; Wright, CD | 1 |
| Fisher, A; Fraser, CM; Gurwitz, D; Haring, R; Heldman, E; Manor, D | 1 |
| Hisamoto, M; Ikeda, T; Itoh, K; Matsuda, K; Mukaiyama, O; Satoh, Y; Yamaguchi, T; Yamamura, N | 1 |
| Asai, F; Matsuda, K; Nakagawa, A; Oshima, T; Sugidachi, A; Takasaki, W; Tanaka, Y; Ushiyama, S | 1 |
| Forghani, F; Keen, S; Ouellet, M; Percival, MD; Tagari, P | 1 |
| Dannhardt, G; Fiebich, B; Kiefer, W; Krämer, G; Maehrlein, S; Nowe, U | 1 |
| Danon, A; Rimon, G; Rosenstock, M; Rubin, M | 1 |
| Bournelis, E; Buerke, M; Fink, L; Grandel, U; Grimminger, F; Heep, M; Kiss, L; Reutemann, M; Seeger, W; Sibelius, U | 1 |
| Levine, L | 1 |
| Cho, N; Endo, S; Furuya, S; Harada, M; Hayase, Y; Imada, T; Imaeda, T; Kasai, S; Matsumoto, H; Sasaki, S; Suzuki, N | 1 |
| Kim, SG; Shin, SM | 1 |
| Cho, IJ; Kim, SG; Kwon, YN; Shin, SM | 1 |
| Barreiro, EJ; Brito, FC; Fraga, CA; Kummerle, AE; Lugnier, C; Miranda, AL | 1 |
| Kim, SG; Koo, JH; Lee, CG; Lee, WH | 1 |
| Gu, Y; Han, Y; Ma, G; Shi, H; Tang, C; Wang, Q; Yan, G | 1 |
| Arrigoni, C; Bryant, C; Clark, KA; Lolicato, M; Minor, DL; Mori, T; Sekioka, Y | 1 |
1 review(s) available for thiophenes and arachidonic acid
| Article | Year |
|---|---|
[Platelet function inhibitors in peripheral arteriopathies].
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis Obliterans; Aspirin; Blood Platelets; Calcium Channel Blockers; Clinical Trials as Topic; Cyclic AMP; Dipyridamole; Extremities; Heparin; Humans; Imidazoles; Prostaglandins; Prostanoic Acids; Pyrazoles; Pyrazolones; Quinacrine; Thiophenes; Thromboembolism; Thrombosis; Ticlopidine; Vascular Diseases | 1986 |
1 trial(s) available for thiophenes and arachidonic acid
| Article | Year |
|---|---|
[Platelet function inhibitors in peripheral arteriopathies].
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis Obliterans; Aspirin; Blood Platelets; Calcium Channel Blockers; Clinical Trials as Topic; Cyclic AMP; Dipyridamole; Extremities; Heparin; Humans; Imidazoles; Prostaglandins; Prostanoic Acids; Pyrazoles; Pyrazolones; Quinacrine; Thiophenes; Thromboembolism; Thrombosis; Ticlopidine; Vascular Diseases | 1986 |
25 other study(ies) available for thiophenes and arachidonic acid
| Article | Year |
|---|---|
Cardiovascular effect and stimulus-dependent inhibition of superoxide generation from human neutrophils by tibenelast, 5,6-diethoxybenzo(b)thiophene-2-carboxylic acid, sodium salt (LY186655).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bronchodilator Agents; Cats; Dogs; Guinea Pigs; Heart Rate; Humans; In Vitro Techniques; Myocardial Contraction; Neutrophils; Phosphodiesterase Inhibitors; Stimulation, Chemical; Superoxides; Thiophenes | 1990 |
RS-5186, a novel, long-acting thromboxane synthetase inhibitor.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Death, Sudden; Dogs; Humans; In Vitro Techniques; Kinetics; Microsomes; Rabbits; Reference Values; Thiophenes; Thromboxane-A Synthase | 1989 |
Pharmacological manipulation of inflammation in rabbit hydronephrosis: effects of a combined cyclooxygenase/lipoxygenase inhibitor ethoxyquin, a thromboxane synthase inhibitor RS-5186 and a PAF antagonist L-659,989.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Ethoxyquin; Fatty Acids, Nonesterified; Furans; Hydronephrosis; Inflammation; Kidney; Leukotriene B4; Lipoxygenase Inhibitors; Male; Perfusion; Platelet Activating Factor; Quinolines; Rabbits; Thiophenes; Thromboxane-A Synthase | 1989 |
Inhibitory effects of three new synthetic compounds on human platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Structure-Activity Relationship; Thiophenes; Thrombin | 1986 |
The effect of oral ticlopidine on arachidonic acid products in human platelets.
Topics: Administration, Oral; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Humans; Malondialdehyde; Platelet Aggregation; Thiophenes; Thromboxane B2; Ticlopidine | 1984 |
The effect of ticlopidine on the aggregation of rat blood platelets and on the formation of metabolites from arachidonic acid and 8,11,14-eicosatrienoic acid in rat platelets during aggregation, and in the rat kidney.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Biotransformation; Blood Platelets; Collagen; Fatty Acids, Unsaturated; Kidney; Male; Platelet Aggregation; Rats; Rats, Inbred Strains; Thiophenes; Ticlopidine | 1982 |
Platelet aggregation measured in rabbit whole blood: in vitro study of 3 aggregating agents and ex vivo inhibition by aspirin and ticlopidine.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; In Vitro Techniques; Platelet Aggregation; Platelet Count; Rabbits; Thiophenes; Ticlopidine | 1982 |
Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cell Adhesion; Dinoprostone; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Indomethacin; Leukocytes; Leukotriene C4; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfhydryl Compounds; Tetrazoles; Thiophenes | 1995 |
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase.
Topics: Animals; Arachidonic Acid; Baculoviridae; Cloning, Molecular; Cyclooxygenase Inhibitors; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Indomethacin; Nitrobenzenes; Oxygen Consumption; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Spodoptera; Sulfonamides; Thiophenes; Time Factors | 1995 |
Selective regulation of human neutrophil functions by the cell activation inhibitor CI-959.
Topics: Arachidonic Acid; Calcium; Calmodulin; Humans; Lysosomes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pentose Phosphate Pathway; Phospholipases; Protein Kinase C; Respiratory Burst; Superoxides; Tetrazoles; Thiophenes | 1994 |
Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Calcium; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Hydrolysis; Phosphatidylinositols; Pilocarpine; Protein Binding; Quinuclidines; Receptors, Cholinergic; Signal Transduction; Thiophenes; Transfection | 1994 |
Alteration of eicosanoid production in the sensitized guinea pig lung by CS-518.
Topics: Administration, Oral; Animals; Arachidonic Acid; Eicosanoids; Guinea Pigs; Histamine; Indomethacin; Lung; Male; Ovalbumin; Prostaglandins; Radioimmunoassay; SRS-A; Thiophenes; Thromboxane A2; Thromboxane-A Synthase; Vaccination | 1993 |
Superiority of plasma 11-dehydro-TXB2 to TXB2 as an index of in vivo TX formation in rabbits after dosing of CS-518, a TX synthase inhibitor.
Topics: Animals; Arachidonic Acid; Eicosanoids; Immunoenzyme Techniques; Infusions, Intravenous; Male; Rabbits; Radioimmunoassay; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1993 |
Analysis of prostaglandin G/H synthase-2 inhibition using peroxidase-induced luminol luminescence.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Binding, Competitive; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indicators and Reagents; Inhibitory Concentration 50; Isoenzymes; Kinetics; Luminol; Membrane Proteins; Peroxidases; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sensitivity and Specificity; Thiophenes; Time Factors | 1998 |
The pyrrole moiety as a template for COX-1/COX-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Isoenzymes; Leukocytes, Mononuclear; Membrane Proteins; Molecular Structure; Monocytes; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrroles; Sulfones; Thiophenes | 2000 |
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes | 2001 |
Staphylococcal alpha-toxin provokes neutrophil-dependent cardiac dysfunction: role of ICAM-1 and cys-leukotrienes.
Topics: Animals; Arachidonic Acid; Bacterial Toxins; Exotoxins; Heart; Hemolysin Proteins; Humans; Hydrazones; In Vitro Techniques; Intercellular Adhesion Molecule-1; Leukotrienes; Myocardium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligonucleotide Probes; Perfusion; Rats; Thiophenes | 2002 |
Tamoxifen and the Rafoxifene analog LY117018: their effects on arachidonic acid release from cells in culture and on prostaglandin I2 production by rat liver cells.
Topics: Animals; Antineoplastic Agents, Hormonal; Arachidonic Acid; Breast Neoplasms; Colonic Neoplasms; Cyclooxygenase 2; Epoprostenol; Estrogen Antagonists; Humans; Isoenzymes; Liver; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 2004 |
Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists.
Topics: Administration, Oral; Animals; Arachidonic Acid; CHO Cells; Cricetinae; Cricetulus; Humans; Macaca fascicularis; Male; Models, Molecular; Molecular Conformation; Pyridines; Pyridones; Radioligand Assay; Rats; Receptors, LHRH; Species Specificity; Structure-Activity Relationship; Thiophenes | 2006 |
Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners.
Topics: Apoptosis; Arachidonic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Formazans; Humans; In Situ Nick-End Labeling; Iron; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Pyrazines; Reactive Oxygen Species; Tetrazolium Salts; Thiones; Thiophenes; Time Factors | 2009 |
Oxidized metabolites of oltipraz exert cytoprotective effects against arachidonic acid through AMP-activated protein kinase-dependent cellular antioxidant effect and mitochondrial protection.
Topics: AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Arachidonic Acid; Cytoprotection; Drug Antagonism; Membrane Potential, Mitochondrial; Mitochondria; Pyrazines; Reactive Oxygen Species; Thiones; Thiophenes; Tumor Cells, Cultured | 2009 |
Novel thienylacylhydrazone derivatives inhibit platelet aggregation through cyclic nucleotides modulation and thromboxane A2 synthesis inhibition.
Topics: Animals; Arachidonic Acid; Bleeding Time; Blood Platelets; Collagen; Female; Humans; Hydrazones; Male; Mice; Molecular Structure; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Thiophenes; Thrombin; Thromboxane A2 | 2010 |
Fyn inhibition by cycloalkane-fused 1,2-dithiole-3-thiones enhances antioxidant capacity and protects mitochondria from oxidative injury.
Topics: AMP-Activated Protein Kinases; Antioxidants; Arachidonic Acid; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cycloparaffins; Hep G2 Cells; Humans; Hydrogen Peroxide; Iron; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-fyn; Superoxides; Thiones; Thiophenes | 2012 |
Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia.
Topics: Animals; Arachidonic Acid; Calcium; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Hypoxia; Male; Muscle Tonus; Oxytocics; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Prostaglandin E; Thiophenes; Triazoles; Vasoconstriction; Xanthones | 2013 |
K
Topics: Animals; Arachidonic Acid; Benzamides; Binding Sites; HEK293 Cells; Humans; Ion Channel Gating; Lipids; Mice; Models, Molecular; Pichia; Potassium Channels, Tandem Pore Domain; Protein Conformation; Sulfonamides; Thiophenes; Xenopus laevis | 2017 |