thiophenes has been researched along with amyloid beta-peptides in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cunningham, AM; Hipkiss, AR; Mayer, S; Michaelis, J; Müller, R; Münch, G; Neumann, A; Riederer, P; Schinzel, R | 1 |
| Beach, TG; Fisher, A; Potter, PE; Sue, LI; Walker, DG | 1 |
| Ho, SA; Kimura, T; Nguyen, PT; Nishijo, H; Ono, T; Tran, AH | 1 |
| Ho, SA; Hong Nguyen, PT; Kimura, T; Nishijo, H; Ono, T; Tran, AH | 1 |
| Hammarström, P; Lindgren, M; Nilsson, KP | 1 |
| Buevich, A; Caldwell, JP; Chen, X; Cox, K; Cumming, JN; Favreau, L; Greenlee, W; Grzelak, M; Hyde, L; Kazakevich, I; Kennedy, ME; Kuvelkar, R; Leach, P; Liu, X; Mandal, M; Mazzola, RD; McKittrick, BA; Orth, P; Parker, EM; Stamford, AW; Strickland, C; Terracina, G; Voigt, J; Wang, H; Zhang, L; Zhang, Q; Zhu, Z | 1 |
| Blazquez-Llorca, L; Brandt Elvang, A; Filser, S; Herms, J; Jung, CK; Masana, M; Müller, MB; Ovsepian, SV; Volbracht, C | 1 |
| Ellis, CR; Hou, X; Shen, J; Tsai, CC | 1 |
| Afzal, CM; Hu, J; Li, G; Ma, R; Shen, W; Wang, L; Wang, M; Wang, X; Yao, Y | 1 |
| da Rocha, DR; Fernandes, L; Kelley, M; Moreira, CS; Palhano, FL; Pereira-Neves, A; Wreden, AB | 1 |
| Burris, TP; Farr, SA; Kermath, BA; Morley, JE; Musiek, ES; Niehoff, M; Roby, DA; Ruiz, F; Voorhees, JR; Zhang, J | 1 |
11 other study(ies) available for thiophenes and amyloid beta-peptides
| Article | Year |
|---|---|
Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Carnosine; Cognition; Cross-Linking Reagents; Fructose; Glycation End Products, Advanced; Guanidines; Humans; Memory; Neuropeptide Y; Particle Size; Peptide Fragments; Piperazines; Protein Structure, Secondary; Solubility; Temperature; Thiazoles; Thiophenes | 1997 |
Reduction of cerebrospinal fluid amyloid beta after systemic administration of M1 muscarinic agonists.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cerebrospinal Fluid; Female; Muscarinic Agonists; Neurons; Peptide Fragments; Piperidines; Quinuclidines; Rabbits; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiazoles; Thiophenes | 2001 |
Ameliorative effects of a neuroprotective agent, T-817MA, on place learning deficits induced by continuous infusion of amyloid-beta peptide (1-40) in rats.
Topics: Amyloid beta-Peptides; Animals; Beclomethasone; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Learning Disabilities; Male; Maleates; Movement; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar; Self Administration; Thiophenes; Time Factors | 2007 |
T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide.
Topics: Amyloid beta-Peptides; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Hippocampus; Injections, Intraventricular; Male; Maleates; Memory; Neural Cell Adhesion Molecule L1; Neurogenesis; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar; Sialic Acids; Spatial Behavior; Thiophenes | 2009 |
A pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections.
Topics: Acetates; Amyloid; Amyloid beta-Peptides; Animals; Brain; Cattle; Drosophila melanogaster; Formaldehyde; Humans; Insulin; Kinetics; Luminescent Agents; Mice; Molecular Imaging; Optical Phenomena; Paraffin Embedding; Peptide Fragments; Polymers; Protein Multimerization; Protein Structure, Secondary; Recombinant Proteins; Thiophenes; Tissue Fixation | 2012 |
Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation.
Topics: Administration, Oral; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Crystallography, X-Ray; HEK293 Cells; Humans; Macaca fascicularis; Models, Molecular; Molecular Conformation; Nitriles; Peptide Fragments; Permeability; Pyrimidines; Pyrimidinones; Quantum Theory; Rats; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Thiophenes | 2012 |
Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Cognition; Cognitive Dysfunction; Dendritic Spines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Pyramidal Cells; Pyrimidines; Pyrimidinones; Synaptic Potentials; Thiazines; Thiophenes; Time Factors | 2015 |
Constant pH Molecular Dynamics Reveals pH-Modulated Binding of Two Small-Molecule BACE1 Inhibitors.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Caco-2 Cells; Hepatocytes; Humans; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Peptide Fragments; Protease Inhibitors; Pyrimidinones; Rats; Thiophenes | 2016 |
Protective effect of 3H-1, 2-dithiole-3-thione on cellular model of Alzheimer's disease involves Nrf2/ARE signaling pathway.
Topics: Active Transport, Cell Nucleus; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoprotection; Down-Regulation; Gene Expression Regulation; Glutathione; Heme Oxygenase-1; Intracellular Space; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; Mice; Mitochondria; Molecular Targeted Therapy; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Response Elements; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Thiones; Thiophenes | 2017 |
Selective and Sensitive Pull Down of Amyloid Fibrils Produced in Vitro and in Vivo by the Use of Pentameric-Thiophene-Coupled Resins.
Topics: Acetates; alpha-Synuclein; Amyloid; Amyloid beta-Peptides; Amyloidosis; Animals; Corneal Dystrophies, Hereditary; Gelsolin; Humans; Mice; Peptide Fragments; Protein Aggregates; Sepharose; Thiophenes | 2018 |
Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Disks Large Homolog 4 Protein; Hippocampus; Male; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Peptide Fragments; Pyrrolidines; Thiophenes | 2019 |