Page last updated: 2024-08-18

thiophenes and alpha-chymotrypsin

thiophenes has been researched along with alpha-chymotrypsin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's9 (81.82)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carey, PR; Tonge, PJ1
Ascenzi, P; Bolognesi, M; Casale, E; Coda, A; La Rosa, C; Luisetti, M; Rizzi, M1
Graham, SL; Hudcosky, RJ; Michelson, SR; Scholz, TH; Schwam, H; Shepard, KL; Smith, AM; Smith, RL; Sondey, JM; Strohmaier, KM1
Baldwin, JJ; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF1
Baici, A; Hörler, D; Pelloso, R1
Baldwin, JJ; Christy, ME; Gautheron, P; Grove, J; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF; Viader, MP1
Donnini, M; Grassi, C; Luisetti, M; Peona, V; Piccioni, PD; Pozzi, E1
Bridges, AJ; Lee, A; Littlefield, BA; Maduakor, EC; Schwartz, CE; Towle, MJ1
Ascenzi, P; Bolognesi, M; Djinovic Carugo, K; Fasano, M; La Rosa, C; Luisetti, M; Rizzi, M1
Debon, C; Hariton, C; Percicot, CL; Schnell, CR1
Brooks, W; Daniel, KG; Ge, Y; Guida, WC; Jain, S; Kazi, A; Lawrence, HR; Luo, Y; Marsilio, F; Sebti, SM1

Other Studies

11 other study(ies) available for thiophenes and alpha-chymotrypsin

ArticleYear
Forces, bond lengths, and reactivity: fundamental insight into the mechanism of enzyme catalysis.
    Biochemistry, 1992, Sep-29, Volume: 31, Issue:38

    Topics: Acylation; Catalysis; Chymotrypsin; Enzymes; Hydrogen Bonding; Indicators and Reagents; Kinetics; Subtilisins; Thermodynamics; Thiophenes

1992
Serine proteinase inhibition by the cyclic thiolic compound YS3025: a crystallographic study.
    Biochemistry international, 1992, Volume: 28, Issue:3

    Topics: Binding Sites; Chymotrypsin; Fourier Analysis; Thiazolidines; Thiophenes; X-Ray Diffraction

1992
Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:10

    Topics: Administration, Topical; Animals; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Chymotrypsin; Glutathione; Intraocular Pressure; Ocular Hypertension; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiophenes

1991
A comparison of L-671,152 and MK-927, two topically effective ocular hypotensive carbonic anhydrase inhibitors, in experimental animals.
    Current eye research, 1990, Volume: 9, Issue:6

    Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chymotrypsin; Ciliary Body; Erythrocytes; Female; In Vitro Techniques; Iris; Light Coagulation; Macaca fascicularis; Male; Ocular Hypertension; Ocular Hypotension; Rabbits; Sulfonamides; Thiophenes; Trabeculectomy

1990
The kinetic mechanism of inhibition of human leukocyte elastase by MR889, a new cyclic thiolic compound.
    Biochemical pharmacology, 1990, Mar-01, Volume: 39, Issue:5

    Topics: Cathepsin B; Cathepsin G; Cathepsins; Chymotrypsin; Humans; In Vitro Techniques; Kinetics; Leukocyte Elastase; Pancreatic Elastase; Protease Inhibitors; Serine Endopeptidases; Substrate Specificity; Thiophenes

1990
MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor.
    Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chymotrypsin; Ciliary Body; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Iris; Kinetics; Macaca fascicularis; Male; Ocular Hypertension; Rabbits; Sulfonamides; Thiophenes

1990
Studies of MR 889, a new synthetic proteinase inhibitor.
    Biochemical and biophysical research communications, 1989, Dec-15, Volume: 165, Issue:2

    Topics: Chymotrypsin; Humans; Kinetics; Pancreatic Elastase; Protease Inhibitors; Sputum; Thiophenes

1989
Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitor.
    Cancer research, 1993, Jun-01, Volume: 53, Issue:11

    Topics: Amidines; Amiloride; Cell Movement; Chymotrypsin; Fibrinolysin; Humans; Kallikreins; Pancreatic Elastase; Thiophenes; Thrombin; Tissue Plasminogen Activator; Trypsin Inhibitors; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1993
Inhibition of serine proteinases belonging to the chymotrypsin superfamily by the cyclic thiolic compound YS3025: a comparative crystallographic study.
    Biochemical and biophysical research communications, 1993, May-28, Volume: 193, Issue:1

    Topics: Animals; Cattle; Chymotrypsin; Pancreas; Pancreatic Elastase; Serine Proteinase Inhibitors; Substrate Specificity; Swine; Thiazolidines; Thiophenes; Trypsin; Trypsin Inhibitors; X-Ray Diffraction

1993
Continuous intraocular pressure measurement by telemetry in alpha-chymotrypsin-induced glaucoma model in the rabbit: effects of timolol, dorzolamide, and epinephrine.
    Journal of pharmacological and toxicological methods, 1996, Volume: 36, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chymotrypsin; Circadian Rhythm; Disease Models, Animal; Epinephrine; Female; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol

1996
Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chymotrypsin; Drug Stability; Humans; Naphthoquinones; Proteasome Inhibitors; Rabbits; Small Molecule Libraries; Structure-Activity Relationship; Sulfonamides; Tetrazoles; Thioglycolates; Thiophenes; Triazoles

2012