Page last updated: 2024-08-18

thiophenes and aflatoxin b1

thiophenes has been researched along with aflatoxin b1 in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (10.00)	18.7374
1990's	21 (70.00)	18.2507
2000's	5 (16.67)	29.6817
2010's	1 (3.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Curphey, TJ; Eaton, DL; Groopman, JD; Kensler, TW; Roebuck, BD	1
Bunyapraphatsara, N; Chulasiri, M; Moongkarndi, P	1
Groopman, JD; Kensler, TW; Liu, YL; Roebuck, BD; Rogers, AE	1
DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A	1
Dolan, PM; Egner, PA; Groopman, JD; Kensler, TW; Roebuck, BD	1
Groopman, JD; Kensler, TW; Liu, YL; Roebuck, BD; Yager, JD	1
Bueding, E; Egner, PA; Groopman, JD; Kensler, TW; Trush, MA	1
Beaune, P; Becquemont, L; Coles, B; Guengerich, FP; Guillouzo, A; Ketterer, B; Langouët, S; Morel, F	1
Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A	1
Egner, PA; Kelloff, GJ; Kensler, TW; Primiano, T; Roebuck, BD; Sutter, TR	1
Kensler, TW; MacMillan, DL; Maxuitenko, YY; Roebuck, BD	1
Coles, B; Gilmore, KS; Guengerich, FP; Harris, J; Harris, TM; Kensler, TW; Ketterer, B; Meyer, DJ; Raney, K	1
Bolton, MG; Groopman, JD; Jacobson, LP; Kensler, TW; Maxuitenko, YY; Muñoz, A; Roebuck, BD	1
Bammler, TK; Buetler, TM; Eaton, DL; Hayes, JD	1
Casto, BC; Chen, J; Li, D; Milo, GE; Noyes, I; Shuler, C; Theil, K	1
Groopman, JD; Kensler, TW; Musser, SM; Scholl, P	1
Coles, B; Guillouzo, A; Ketterer, B; Langouet, S; Maheo, K; Morel, F	1
Groopman, JD; Kensler, TW	1
Kensler, TW; Roebuck, BD; Rogers, AE	1
Berthou, F; Coles, B; Glaise, D; Guillouzo, A; Ketterer, B; Lagadic-Gossman, D; Langouët, S; Mahéo, K; Morel, F	1
Kensler, TW	1
Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A; Roebuck, BD; Rogers, AE	1
Curphey, TJ; Joyner, HH; Kensler, TW; Libby, AH; MacMillan, DL; Maxuitenko, YY; Roebuck, BD	1
Egner, PA; Groopman, JD; He, X; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Muñoz, A; Qian, GS; Shen, X; Wang, JB; Wang, JS; Zarba, A; Zhang, BC; Zhu, YR	1
Bammler, TK; Eaton, DL; Slone, DH	1
Egner, PA; Groopman, JD; Kensler, TW; Li, Y; Qin, L; Roebuck, BD; Su, J; Wang, J	1
Dolan, PM; Egner, PA; Groopman, JD; Itoh, K; Kensler, TW; Kwak, MK; Ramos-Gomez, M; Yamamoto, M	1
Fautrel, A; Guillouzo, A; Langouët, S; Salles, B; Sparfel, L	1
Baumgartner, KJ; Bodreddigari, S; Curphey, TJ; Gange, SJ; Kensler, TW; Li, Y; Roebuck, BD; Sutter, TR; Yan, J	1
Longford, NT	1

Reviews

3 review(s) available for thiophenes and aflatoxin b1

Article	Year
Carcinogen-DNA and protein adducts: biomarkers for cohort selection and modifiable endpoints in chemoprevention trials. Journal of cellular biochemistry. Supplement, 1996, Volume: 25 Topics: Aflatoxin B1; Aflatoxins; Aged; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Clinical Trials as Topic; Cohort Studies; DNA Adducts; Guanine; Hepatitis B; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Proteins; Pyrazines; Risk Factors; Thiones; Thiophenes	1996
Chemoprevention by inducers of carcinogen detoxication enzymes. Environmental health perspectives, 1997, Volume: 105 Suppl 4 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Enzyme Induction; Humans; Liver Neoplasms; Pyrazines; Rats; Thiones; Thiophenes	1997
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones. Mutation research, 2001, Sep-01, Volume: 480-481 Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Carcinogens; Chemoprevention; China; Controlled Clinical Trials as Topic; Enzyme Induction; Gene Expression; Glucuronosyltransferase; Glutathione Transferase; Humans; Inactivation, Metabolic; Liver Neoplasms; Pyrazines; Quinone Reductases; Thiones; Thiophenes	2001

Trials

1 trial(s) available for thiophenes and aflatoxin b1

Article	Year
Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China. Journal of the National Cancer Institute, 1999, Feb-17, Volume: 91, Issue:4 Topics: Acetylcysteine; Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; China; Cytochrome P-450 CYP1A2; Double-Blind Method; Drug Administration Schedule; Feasibility Studies; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Liver Neoplasms; Pyrazines; Reproducibility of Results; Thiones; Thiophenes; Treatment Outcome	1999

Article

Year

Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China.

Journal of the National Cancer Institute, 1999, Feb-17, Volume: 91, Issue:4

Topics: Acetylcysteine; Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; China; Cytochrome P-450 CYP1A2; Double-Blind Method; Drug Administration Schedule; Feasibility Studies; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Liver Neoplasms; Pyrazines; Reproducibility of Results; Thiones; Thiophenes; Treatment Outcome

1999

Other Studies

26 other study(ies) available for thiophenes and aflatoxin b1

Article	Year
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione. Carcinogenesis, 1992, Volume: 13, Issue:1 Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1992
Mutagenicity and antimutagenicity of hispidulin and hortensin, the flavonoids from Millingtonia hortensis L. Environmental and molecular mutagenesis, 1992, Volume: 20, Issue:4 Topics: Aflatoxin B1; Anthracenes; Antimutagenic Agents; Azides; Cell Survival; Dimethylnitrosamine; Flavones; Flavonoids; Microsomes, Liver; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Sodium Azide; Suppression, Genetic; Thiophenes	1992
Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry. Cancer research, 1991, Oct-15, Volume: 51, Issue:20 Topics: Adenoma; Aflatoxin B1; Animals; DNA; gamma-Glutamyltransferase; Growth; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Survival Analysis; Thiones; Thiophenes	1991
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats. Carcinogenesis, 1992, Volume: 13, Issue:1 Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes	1992
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones. Cancer research, 1987, Aug-15, Volume: 47, Issue:16 Topics: Aflatoxin B1; Aflatoxins; Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Heterocyclic Compounds; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiones; Thiophenes	1987
Protection by 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) against the hepatotoxicity of aflatoxin B1 in the rat. Toxicology and applied pharmacology, 1988, Volume: 93, Issue:3 Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Butylated Hydroxytoluene; DNA; Enzyme Induction; Glutathione Transferase; Liver; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1988
Modification of aflatoxin B1 binding to DNA in vivo in rats fed phenolic antioxidants, ethoxyquin and a dithiothione. Carcinogenesis, 1985, Volume: 6, Issue:5 Topics: Aflatoxin B1; Aflatoxins; Animals; Anisoles; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Ethoxyquin; Glutathione Transferase; Kidney; Liver; Male; Pyrazines; Quinolines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1985
Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture. Cancer research, 1995, Dec-01, Volume: 55, Issue:23 Topics: Aflatoxin B1; Aged; Anticarcinogenic Agents; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Glutathione Transferase; Humans; Infant; Liver; Male; Methylcholanthrene; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Pyrazines; Rifampin; Thiones; Thiophenes; Time Factors	1995
Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz. Carcinogenesis, 1995, Volume: 16, Issue:8 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers; Male; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes	1995
Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases. Cancer research, 1995, Oct-01, Volume: 55, Issue:19 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Enzyme Induction; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1995
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis. Carcinogenesis, 1993, Volume: 14, Issue:11 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Body Weight; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes; Time Factors	1993
Induction of rat liver GSH transferases by 1,2-dithiole-3-thione illustrates both anticarcinogenic and tumor-promoting properties. Basic life sciences, 1993, Volume: 61 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cytosol; Enzyme Induction; Glutathione Transferase; Inactivation, Metabolic; Liver; Macromolecular Substances; Phenobarbital; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes	1993
Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis. Cancer research, 1993, Aug-01, Volume: 53, Issue:15 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; DNA Adducts; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1993
Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention. Cancer research, 1996, May-15, Volume: 56, Issue:10 Topics: Aflatoxin B1; Aflatoxins; Animals; Anticarcinogenic Agents; Base Sequence; Biotransformation; Carcinogens; Clofibric Acid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Glutathione Transferase; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Pregnenolone Carbonitrile; Pyrazines; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Species Specificity; Steroid Hydroxylases; Thiones; Thiophenes	1996
Malignant conversion of chemically transformed normal human cells. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11 Topics: Aflatoxin B1; Animals; Avian Sarcoma Viruses; Base Sequence; Blotting, Southern; Carcinogens; Carcinoma; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 7; DNA Primers; Epithelium; Gene Conversion; Humans; Infant, Newborn; Male; Methyl Methanesulfonate; Mice; Mice, Nude; Molecular Sequence Data; Polymerase Chain Reaction; Skin; Thiophenes; Transcription, Genetic; Transfection; Transplantation, Heterologous	1996
Inhibition of aflatoxin Ml excretion in rat urine during dietary intervention with oltipraz. Carcinogenesis, 1996, Volume: 17, Issue:6 Topics: Aflatoxin B1; Aflatoxin M1; Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1996
Metabolism of aflatoxin B1 by human hepatocytes in primary culture. Advances in experimental medicine and biology, 1996, Volume: 387 Topics: Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; Cells, Cultured; Enzyme Induction; Glutathione; Glutathione Transferase; Humans; Liver; Methylcholanthrene; Pyrazines; Thiones; Thiophenes	1996
Correspondence re: C.V. Rao, et al., Inhibition of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced lymphoma formation by oltipraz. Cancer Res., 56: 3395-3398, 1996. Cancer research, 1997, Jul-01, Volume: 57, Issue:13 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Hematologic Neoplasms; Imidazoles; Lymphoma; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1997
Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture. Carcinogenesis, 1997, Volume: 18, Issue:7 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Caffeine; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Liver; Male; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiones; Thiophenes	1997
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:8 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1997
Identification of dithiolethiones with better chemopreventive properties than oltipraz. Carcinogenesis, 1998, Volume: 19, Issue:9 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Enzyme Induction; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes	1998
Effects of dietary oltipraz and ethoxyquin on aflatoxin B1 biotransformation in non-human primates. Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 54, Issue:1 Topics: Aflatoxin B1; Albumins; Animals; Anticarcinogenic Agents; Biotransformation; Callithrix; Carcinogens; Cytosol; Diet; DNA Adducts; Ethoxyquin; Glutathione Transferase; Humans; In Vitro Techniques; Macaca nemestrina; Male; Microsomes, Liver; Oxidation-Reduction; Pyrazines; Species Specificity; Teratogens; Thiones; Thiophenes	2000
Reduction of aflatoxin B(1) adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis). Cancer letters, 2000, Jun-01, Volume: 154, Issue:1 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antiviral Agents; Biomarkers; Chromatography, High Pressure Liquid; DNA Adducts; Female; Hepatitis B virus; Humans; Liver Neoplasms; Male; Pyrazines; Radioimmunoassay; Thiones; Thiophenes; Time Factors; Tupaiidae	2000
Investigations on the effects of oltipraz on the nucleotide excision repair in the liver. Biochemical pharmacology, 2002, Feb-15, Volume: 63, Issue:4 Topics: Aflatoxin B1; Animals; DNA; DNA Adducts; DNA Repair; Hepatocytes; Humans; Liver; Male; Pyrazines; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Thiones; Thiophenes	2002
Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz. Carcinogenesis, 2003, Volume: 24, Issue:12 Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Blotting, Western; Carcinogens; DNA; DNA Adducts; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Immunoblotting; Liver; Male; Models, Chemical; Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Pyrazines; Rats; Rats, Inbred F344; RNA; RNA, Messenger; Temperature; Thiones; Thiophenes; Time Factors	2003
Handling the limit of detection by extrapolation. Statistics in medicine, 2012, Nov-20, Volume: 31, Issue:26 Topics: Aflatoxin B1; Analysis of Variance; Biostatistics; Chemoprevention; Data Interpretation, Statistical; Humans; Limit of Detection; Linear Models; Models, Statistical; Pyrazines; Randomized Controlled Trials as Topic; Regression Analysis; Thiones; Thiophenes	2012