Page last updated: 2024-08-18

thiophenes and 3-methylcholanthrene

thiophenes has been researched along with 3-methylcholanthrene in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beaune, P; Becquemont, L; Coles, B; Guengerich, FP; Guillouzo, A; Ketterer, B; Langouët, S; Morel, F1
Fardel, O; Gilmore, KS; Guillouzo, A; Kensler, TW; Ketterer, B; Langouet, S; Meunier, B; Meyer, DJ; Morel, F; Tu, CP1
Bammler, TK; Buetler, TM; Eaton, DL; Hayes, JD1
Ellis, EM; Hayes, JD; Judah, DJ; Neal, GE; O'Connor, T1
Corcos, L; Fardel, O; Guillouzo, A; Ketterer, B; Langouët, S; Meyer, DJ; Morel, F1
Coles, B; Guillouzo, A; Ketterer, B; Langouet, S; Maheo, K; Morel, F1
Auyeung, DJ; Kessler, FK; Ritter, JK1
Cho, IJ; Kim, SG1
Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ1
Boyer, JL; Cai, SY; Soroka, CJ; Weerachayaphorn, J; Xu, S1

Other Studies

10 other study(ies) available for thiophenes and 3-methylcholanthrene

ArticleYear
Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23

    Topics: Aflatoxin B1; Aged; Anticarcinogenic Agents; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Glutathione Transferase; Humans; Infant; Liver; Male; Methylcholanthrene; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Pyrazines; Rifampin; Thiones; Thiophenes; Time Factors

1995
Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene, and dithiolethiones.
    Cancer research, 1993, Jan-15, Volume: 53, Issue:2

    Topics: Cells, Cultured; Enzyme Induction; Gene Expression; Glutathione Transferase; Humans; Liver; Methylcholanthrene; Phenobarbital; Pyrazines; RNA, Messenger; Thiones; Thiophenes

1993
Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Aflatoxin B1; Aflatoxins; Animals; Anticarcinogenic Agents; Base Sequence; Biotransformation; Carcinogens; Clofibric Acid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Glutathione Transferase; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Pregnenolone Carbonitrile; Pyrazines; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Species Specificity; Steroid Hydroxylases; Thiones; Thiophenes

1996
Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors.
    Cancer research, 1996, Jun-15, Volume: 56, Issue:12

    Topics: Aldehyde Reductase; Animals; Antioxidants; Barbiturates; Butylated Hydroxyanisole; Carcinogens; Enzyme Induction; Ethoxyquin; Liver; Methylcholanthrene; Oxidation-Reduction; Phenobarbital; Pyrazines; Rats; Thiones; Thiophenes

1996
A comparison of the effect of inducers on the expression of glutathione-S-transferases in the liver of the intact rat and in hepatocytes in primary culture.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:4

    Topics: Animals; Cells, Cultured; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Liver; Male; Methylcholanthrene; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiones; Thiophenes

1996
Metabolism of aflatoxin B1 by human hepatocytes in primary culture.
    Advances in experimental medicine and biology, 1996, Volume: 387

    Topics: Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; Cells, Cultured; Enzyme Induction; Glutathione; Glutathione Transferase; Humans; Liver; Methylcholanthrene; Pyrazines; Thiones; Thiophenes

1996
An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.
    Toxicology and applied pharmacology, 2001, Jul-01, Volume: 174, Issue:1

    Topics: 5' Untranslated Regions; Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Digestive System; DNA, Complementary; Exons; Gene Expression; Glucuronosyltransferase; Humans; Kidney; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Promoter Regions, Genetic; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Thiones; Thiophenes

2001
Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Animals; Anticarcinogenic Agents; Binding Sites; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cell Line; Cytochrome P-450 CYP1A1; DNA; Gene Expression; Genes, Reporter; Hepatocytes; Luciferases; Methylcholanthrene; Mutation; Promoter Regions, Genetic; Pyrazines; Rats; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Thiones; Thiophenes; Transcriptional Activation; Transfection

2003
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes

2005
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 299, Issue:1

    Topics: 5' Flanking Region; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Butylamines; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Genes, Reporter; Hep G2 Cells; Hepatocytes; Humans; Methylcholanthrene; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutation; NF-E2-Related Factor 2; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Pyrazines; Receptors, Aryl Hydrocarbon; Response Elements; RNA Interference; RNA, Messenger; Thiones; Thiophenes; Time Factors; Transfection

2010