thiohydantoins and 2-phenylglycine

thiohydantoins has been researched along with 2-phenylglycine* in 1 studies

Other Studies

1 other study(ies) available for thiohydantoins and 2-phenylglycine

Article	Year
Synthesis of new imidazolidin-2,4-dione and 2-thioxoimidazolidin-4-ones via C-phenylglycine derivatives. Molecules (Basel, Switzerland), 2009, Dec-30, Volume: 15, Issue:1 Hydantoins and their derivatives constitute a group of pharmaceutical compounds with anticonvulsant and antiarrhythmic properties, and are also used against diabetes. N-3 and C-5 substituted imidazolidines are examples of such products. As such, we have developed a synthesis of 2,4-dione and 2-thioxo-4-one imidazolidinic derivatives by reaction of amino acids with C-phenylglycine, phenyl isocyanate and phenyl isothiocyanate. Four amino-derivatives IG(1-4) and eight imidazolidinic derivatives, IM(1-8), were obtained in yields of 70-74%. The mass, infrared, (1)H and (13)C-NMR spectra of representative products are discussed. Topics: Glycine; Imidazolidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thiohydantoins	2009

Article

Year

Synthesis of new imidazolidin-2,4-dione and 2-thioxoimidazolidin-4-ones via C-phenylglycine derivatives.

Molecules (Basel, Switzerland), 2009, Dec-30, Volume: 15, Issue:1

Hydantoins and their derivatives constitute a group of pharmaceutical compounds with anticonvulsant and antiarrhythmic properties, and are also used against diabetes. N-3 and C-5 substituted imidazolidines are examples of such products. As such, we have developed a synthesis of 2,4-dione and 2-thioxo-4-one imidazolidinic derivatives by reaction of amino acids with C-phenylglycine, phenyl isocyanate and phenyl isothiocyanate. Four amino-derivatives IG(1-4) and eight imidazolidinic derivatives, IM(1-8), were obtained in yields of 70-74%. The mass, infrared, (1)H and (13)C-NMR spectra of representative products are discussed.

Topics: Glycine; Imidazolidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thiohydantoins

2009