thioctic acid and ubiquinone

thioctic acid has been researched along with ubiquinone in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19907 (10.14)18.7374
1990's3 (4.35)18.2507
2000's25 (36.23)29.6817
2010's29 (42.03)24.3611
2020's5 (7.25)2.80

Authors

AuthorsStudies
Guest, JR; Watts, DJ1
Kirk, JE1
Leclerc, M1
Ragan, CI; Tottmar, SO1
McCarty, MF2
McCarty, MF; Rubin, EJ1
Burger, R; Chan, WW; Chen, SC; Dirr, A; Götz, ME; Janetzky, B; Rausch, WD; Reichmann, H; Riederer, P; Weinmüller, M1
Gille, L; Nohl, H; Staniek, K1
Gille, L; Kozlov, AV; Nohl, H; Staniek, K1
Patrick, L1
Grundmann-Kollmann, M; Kaufmann, R; Packer, L; Podda, M; Thiele, JJ; Zollner, TM1
Elstner, EF; Schneider, D1
Bondy, SC; Gie, YW; Lahiri, DK; Walsh, TJ; Yang, YE1
Piotrowski, P; Smiałek, M; Wierzbicka, K1
Chang, CM; Chen, HJ; Chen, YM1
Beal, MF1
Bates, GP; Hockly, E1
Ernst, A; Grune, T; Sandig, G; Stolzing, A1
Allison, DB; Edwards, J; Klopp, RG; Lee, CK; Prolla, TA; Pugh, TD; Weindruch, R1
Baker, TR; Hoffmann-Benning, S; Husain, RD; MacDonald, MJ1
Hadj, A; Marasco, S; Miller, F; Nagley, P; Pepe, S; Quick, D; Rosenfeldt, F; Sheeran, F; Wowk, M1
Bonnefont-Rousselot, D1
Belloto, RJ; Hudson, RA; McInerney, MF; Schroeder, MM1
Park, SK; Prolla, TA1
Donahue, JJ; Guan, J; Kennedy, AR; Wan, XS; Ware, JH; Zhou, Z1
Feher, J; Lengyel, G; Nagy, V; Németh, E1
Beal, MF; MacDonald, JR; Mahoney, DJ; Parise, G; Rodriguez, MC; Tarnopolsky, MA1
Hadj, A; Pepe, S; Rosenfeldt, F1
Levin, RM; Lin, WY; Rehfuss, A; Schuler, C1
Chuang, SM; Huang, CH; Hydery, T; Juan, YS; Kogan, B; Levin, RM; Li, S; Mannikarottu, A; Schuler, C1
Ayaz, M; Gokbel, H; Okudan, N; Tuncer, S1
Filosto, M; Mancuso, M; Orsucci, D; Siciliano, G1
Bentov, Y; Burstein, E; Casper, RF; Esfandiari, N1
Andrisano, V; Bartolini, M; Bergamini, C; Bolognesi, ML; Cavalli, A; Fato, R; Lenaz, G; Melchiorre, C; Rosini, M1
Golbidi, S; Laher, I1
Graf, J1
Brenner, SR1
Leggett, RE; Levin, RM; Li, HT; Schuler, C1
de Freitas, RM; Feng, D; Jordán, J1
de Freitas, RM; Gomes, KN; Saldanha, GB1
Ebadi, SA; Golbidi, S; Laher, I1
Leggett, RE; Levin, RM; Radu, F; Schuler, C1
Firuzi, O; Miri, R; Saso, L; Tavakkoli, M1
Jazbec-Križman, P; Kotnik, D; Križman, M; Prošek, M; Smidovnik, A1
Aisen, P; Clark, CM; Cotman, C; Cottrell, B; Galasko, DR; Jicha, GA; Montine, TJ; Peskind, E; Quinn, JF; Ringman, JM; Thomas, RG1
Chinnery, PF; Majamaa, K; Pfeffer, G; Thorburn, D; Turnbull, DM1
Barella, L; Birringer, M; Ernst, IM; Rimbach, G; Sancak, O; Wagner, AE1
Abadi, A; Akhtar, M; Crane, JD; Hettinga, B; Macneil, L; Ogborn, D; Safdar, A; Stokl, A; Tarnopolsky, M1
Chubb, HA; Fisher, G; Orringer, J; Rittié, L; Sachs, DL; Voorhees, JJ1
Phillipson, OT1
Feng, Z; Li, Y; Liu, J; Long, J; Peng, Y; Qu, L; Shi, W1
Balduzzi, V; Bernardini, N; La Viola, G; Mancini, MT; Nicolucci, F; Pampena, R; Potenza, C; Proietti, I; Skroza, N; Soccodato, V; Tolino, E; Zuber, S1
Nicolson, GL1
Bhadri, N; Madakasira Guggilla, H; Razdan, R; Sanji, T1
Ni, SL; Sun, R; Xia, Q; Zhao, GD1
Bolar, NA; Bruhn, H; Freyer, C; Govaert, P; Jespers, A; Kishita, Y; Kohda, M; Lesko, N; Loeys, BL; Maffezzini, C; Marobbio, CM; Miniero, DV; Monné, M; Mourier, A; Murayama, K; Naess, K; Nennesmo, I; Ohtake, A; Okazaki, Y; Pajak, A; Palmieri, F; Stranneheim, H; Van Laer, L; Wedell, A; Wibom, R; Wredenberg, A1
Al-Doghather, HA; Al-Ghamdi, MA; Choudhry, H; Huwait, EH; Kumosani, TA; Moselhy, SS1
Crascì, L; Modica, MN; Montenegro, L; Panico, AM; Puglisi, G; Romeo, G; Salerno, L1
Hu, C; Xue, Y; Zhao, G1
Cross, AH; Evans, E; Piccio, L1
Cintoni, M; Mele, MC; Pizzoferrato, M; Rinninella, E; Servidei, S1
Abdollahi, M; Baeeri, M; Davoodzadeh Gholami, M; Falak, R; Hassani, S; Hassanzadeh, G; Hosseini, A; Jamshidzade, A; Mokhtari, T; Najafi, R; Rahimifard, M; Sadeghiyan Galeshkalami, N1
Comhaire, F; Deslypere, JP1
Fittipaldi, MR; Lyakhovich, A; Pagano, G; Pallardó, FV; Tiano, L; Toscanesi, M; Trifuoggi, M1
Augustyniak, J; Bhattacharya, M; Cheung, M; Dutta, A; Karanth, SS; Liput, M; Stachowiak, EK; Stachowiak, MK1
Lyakhovich, A; Manfredi, C; Pagano, G; Pallardó, FV; Tiano, L; Trifuoggi, M1
Li, M; Ning, B; Wang, T1

Reviews

20 review(s) available for thioctic acid and ubiquinone

ArticleYear
Nutrients and HIV: part three - N-acetylcysteine, alpha-lipoic acid, L-glutamine, and L-carnitine.
    Alternative medicine review : a journal of clinical therapeutic, 2000, Volume: 5, Issue:4

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Carnitine; Complementary Therapies; Glutamine; HIV Infections; Humans; Thioctic Acid; Ubiquinone

2000
Anti-aging products, Part I. Can supplements rewind our body clocks?
    Harvard women's health watch, 2001, Volume: 9, Issue:4

    Topics: Advertising; Aging; Antioxidants; Coenzymes; Dietary Supplements; Evidence-Based Medicine; Humans; Patient Education as Topic; S-Adenosylmethionine; Superoxide Dismutase; Thioctic Acid; Ubiquinone

2001
Bioenergetic approaches for neuroprotection in Parkinson's disease.
    Annals of neurology, 2003, Volume: 53 Suppl 3

    Topics: Acetylcarnitine; Coenzymes; Creatine; Energy Metabolism; Free Radicals; Ginkgo biloba; Humans; Mitochondria; Neuroprotective Agents; Niacinamide; Nootropic Agents; Parkinson Disease; Phytotherapy; Thioctic Acid; Ubiquinone

2003
Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials?
    Current opinion in neurology, 2003, Volume: 16, Issue:4

    Topics: Acetamides; Animals; Antioxidants; Creatine; Disease Models, Animal; Evaluation Studies as Topic; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Peptides; Point Mutation; Riluzole; Thioctic Acid; Trinucleotide Repeats; Ubiquinone

2003
The role of antioxidant micronutrients in the prevention of diabetic complications.
    Treatments in endocrinology, 2004, Volume: 3, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Diabetes Complications; Diet; Flavonoids; Humans; Metals; Micronutrients; Niacinamide; Riboflavin; Thioctic Acid; Tocopherols; Ubiquinone; Vitamins

2004
Gene expression profiling studies of aging in cardiac and skeletal muscles.
    Cardiovascular research, 2005, May-01, Volume: 66, Issue:2

    Topics: Aging; Animals; Caloric Restriction; Coenzymes; Gene Expression Profiling; Humans; Mice; Muscle, Skeletal; Myocardium; Myocytes, Cardiac; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Thioctic Acid; Ubiquinone

2005
[The role of antioxidants in prevention].
    Orvosi hetilap, 2006, Apr-02, Volume: 147, Issue:13

    Topics: Antioxidants; Coenzymes; Dietary Supplements; Fatty Acids, Omega-3; Free Radical Scavengers; Free Radicals; Humans; Oxidative Stress; Primary Prevention; Selenium; Thioctic Acid; Ubiquinone; Vitamin E

2006
The clinical application of metabolic therapy for cardiovascular disease.
    Heart, lung & circulation, 2007, Volume: 16 Suppl 3

    Topics: Adaptation, Physiological; Cardiovascular Diseases; Coenzymes; Exercise; Glucose; Heart Failure; Humans; Hypertension; Insulin; Meditation; Orotic Acid; Physical Therapy Modalities; Potassium; Thioctic Acid; Ubiquinone

2007
Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction.
    Nutrition reviews, 2009, Volume: 67, Issue:8

    Topics: Acidosis, Lactic; Animals; Antioxidants; Carnitine; Creatine; Dietary Supplements; Electron Transport; Humans; Mitochondrial Diseases; Succinic Acid; Thioctic Acid; Ubiquinone; Vitamin B Complex; Vitamins

2009
Antioxidant therapy in human endocrine disorders.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Diabetes Mellitus; Female; Humans; Infertility; Male; Oxidative Stress; Reactive Oxygen Species; Thioctic Acid; Thyroid Diseases; Ubiquinone; Vitamin E

2010
Antioxidants and skin care: the essentials.
    Plastic and reconstructive surgery, 2010, Volume: 125, Issue:1

    Topics: Aging; Antioxidants; Ascorbic Acid; Electron Transport Chain Complex Proteins; Flavonoids; Humans; Phenols; Polyphenols; Skin Care; Thioctic Acid; Ubiquinone

2010
Antioxidants in the treatment of diabetes.
    Current diabetes reviews, 2011, Volume: 7, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Carnitine; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Indoles; Male; Maleimides; Oxidative Stress; Thioctic Acid; Treatment Outcome; Ubiquinone; Vitamins

2011
Antioxidant therapy: current status and future prospects.
    Current medicinal chemistry, 2011, Volume: 18, Issue:25

    Topics: Acetylcysteine; Animals; Antioxidants; Antipyrine; Ascorbic Acid; Edaravone; Humans; Polyphenols; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin E

2011
Treatment for mitochondrial disorders.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: Creatine; Dichloroacetic Acid; Humans; Mitochondrial Diseases; Randomized Controlled Trials as Topic; Sarcosine; Thioctic Acid; Ubiquinone

2012
Hypo-collagenesis in photoaged skin predicts response to anti-aging cosmeceuticals.
    Journal of cosmetic dermatology, 2013, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Cell Extracts; Cosmetics; Female; Humans; Male; Middle Aged; Procollagen; Protein Biosynthesis; Skin; Skin Aging; Thioctic Acid; Ubiquinone; Yeasts

2013
Management of the aging risk factor for Parkinson's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:4

    Topics: Acetylcarnitine; Adenosine Triphosphate; Aging; alpha-Synuclein; Antioxidant Response Elements; Carbohydrate Metabolism; Electron Transport; Energy Metabolism; Fatty Acids; Glial Cell Line-Derived Neurotrophic Factor; Humans; Inflammation; Melatonin; Mitochondria; Nitric Oxide; Oxidative Stress; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Proteostasis Deficiencies; Risk Factors; Thioctic Acid; Transcription Factors; Ubiquinone

2014
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
    JAMA neurology, 2018, 08-01, Volume: 75, Issue:8

    Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Unsaturated; Folic Acid; Ginkgo biloba; Humans; Multiple Sclerosis; Niacin; Pantothenic Acid; Plant Preparations; Probiotics; Pyridoxine; Resveratrol; Riboflavin; Tea; Thiamine; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamins

2018
Aging-Related Disorders and Mitochondrial Dysfunction: A Critical Review for Prospect Mitoprotective Strategies Based on Mitochondrial Nutrient Mixtures.
    International journal of molecular sciences, 2020, Sep-25, Volume: 21, Issue:19

    Topics: Aging; Animals; Antioxidants; Cardiovascular Diseases; Carnitine; Cell Line; Diabetes Mellitus, Type 2; Humans; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Thioctic Acid; Ubiquinone

2020
Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2021, Volume: 70, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Carnitine; Chemotherapy, Adjuvant; COVID-19 Drug Treatment; Humans; Mitochondria; SARS-CoV-2; Sepsis; Thioctic Acid; Ubiquinone

2021
The mechanism and prevention of mitochondrial injury after exercise.
    Journal of physiology and biochemistry, 2021, Volume: 77, Issue:2

    Topics: Apoptosis; Athletic Injuries; Calcium; Dietary Supplements; DNA Damage; Exercise; Fatigue; Free Radicals; Humans; Lipid Peroxidation; Mitochondria; Nitric Oxide; Phenylethyl Alcohol; Resveratrol; Thioctic Acid; Ubiquinone

2021

Trials

4 trial(s) available for thioctic acid and ubiquinone

ArticleYear
Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders.
    Muscle & nerve, 2007, Volume: 35, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Analysis of Variance; Antioxidants; Body Composition; Child; Coenzymes; Creatine; Creatinine; Cross-Over Studies; Deoxyguanosine; Dinoprost; Double-Blind Method; Female; Humans; Male; Middle Aged; Mitochondrial Diseases; Thioctic Acid; Ubiquinone

2007
Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures.
    Archives of neurology, 2012, Volume: 69, Issue:7

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; alpha-Tocopherol; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Ascorbic Acid; Biomarkers; Cholinesterase Inhibitors; Dietary Supplements; Double-Blind Method; F2-Isoprostanes; Female; Follow-Up Studies; Humans; Male; Memantine; Mental Status Schedule; Middle Aged; Peptide Fragments; Retrospective Studies; tau Proteins; Thioctic Acid; Ubiquinone

2012
Efficacy of food supplement to improve metabolic syndrome parameters in patients affected by moderate to severe psoriasis during anti-TNFα treatment.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2013, Volume: 148, Issue:6

    Topics: Adult; Animals; Antioxidants; Biomarkers; Body Mass Index; Cholesterol, HDL; Dietary Fats, Unsaturated; Dietary Supplements; Etanercept; Euphausiacea; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Metabolic Syndrome; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Resveratrol; Seeds; Selenium; Severity of Illness Index; Stilbenes; Thioctic Acid; Treatment Outcome; Triglycerides; Tumor Necrosis Factor-alpha; Ubiquinone; Vitamin E; Vitis

2013
News and views in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): The role of co-morbidity and novel treatments.
    Medical hypotheses, 2020, Volume: 134

    Topics: Adult; Animals; Antiviral Agents; Autoimmune Diseases; Comorbidity; Dichloroacetic Acid; Dietary Supplements; Drug Evaluation, Preclinical; Drug Therapy, Combination; Endocrine System Diseases; Fatigue Syndrome, Chronic; Female; Humans; Infections; Insulin Resistance; Male; Mental Disorders; Methylhydrazines; Middle Aged; Mitochondria; Neuroimaging; Pyruvate Dehydrogenase Complex; Severity of Illness Index; Thiamine; Thioctic Acid; Tomography, Emission-Computed, Single-Photon; Ubiquinone

2020

Other Studies

45 other study(ies) available for thioctic acid and ubiquinone

ArticleYear
Studies on the vitamin nutrition of the cellular slime mould Dictyostelium discoideum.
    Journal of general microbiology, 1975, Volume: 86, Issue:2

    Topics: Aminobenzoates; Bacillus megaterium; Biotin; Culture Media; Enterococcus faecalis; Escherichia coli; Folic Acid; Mutation; Myxomycetes; Nicotinic Acids; Pantothenic Acid; Thiamine; Thioctic Acid; Ubiquinone; Vitamin B 12; Vitamin B Complex; Vitamins

1975
Coenzyme contents of arterial tissue.
    Monographs on atherosclerosis, 1974, Volume: 4, Issue:0

    Topics: Age Factors; Animals; Aorta; Arteries; Arteriosclerosis; Carnitine; Chromatography, Paper; Coenzyme A; Coenzymes; Creatine; Cytochrome c Group; Dipeptides; DNA; Glutathione; Guinea Pigs; Humans; Nucleotides; Oxidation-Reduction; Pulmonary Artery; RNA; Spectrophotometry; Thioctic Acid; Ubiquinone

1974
[Coenzymes (vitamins)].
    L' Alimentation et la vie, 1970, Volume: 58, Issue:1

    Topics: Ascorbic Acid; Biotin; Chemical Phenomena; Chemistry; Coenzyme A; Coenzymes; Cytochromes; Flavin-Adenine Dinucleotide; Folic Acid; Glutathione; NAD; NADP; Nucleosides; Pyridoxine; Thiamine; Thioctic Acid; Ubiquinone; Vitamins

1970
The purification and properties of the respiratory-chain reduced nicotinamide--adenine dinucleotide dehydrogenase of Torulopsis utilis.
    The Biochemical journal, 1971, Volume: 124, Issue:5

    Topics: Cytochromes; Electron Spin Resonance Spectroscopy; Ferricyanides; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Imines; Iron; Kinetics; Mitochondria; Mitosporic Fungi; NAD; NADP; Oxidoreductases; Phenotype; Quinones; Spectrophotometry; Sulfides; Thioctic Acid; Ubiquinone; Vitamin K

1971
Maturity-onset diabetes mellitus--toward a physiological appropriate management.
    Medical hypotheses, 1981, Volume: 7, Issue:10

    Topics: Amino Acids; Aspirin; Carnitine; Chromium; Diabetes Mellitus; Dietary Fats; Dietary Fiber; Fasting; Humans; Nicotinic Acids; Organometallic Compounds; Pyridoxine; Thioctic Acid; Ubiquinone

1981
Rationales for micronutrient supplementation in diabetes.
    Medical hypotheses, 1984, Volume: 13, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Carnitine; Chromium; Diabetes Mellitus; gamma-Linolenic Acid; Humans; Linolenic Acids; Magnesium; Pyridoxine; Selenium; Thioctic Acid; Ubiquinone; Vitamin E; Zinc

1984
Toward a "bio-energy supplement" -- a prototype for functional orthomolecular supplementation.
    Medical hypotheses, 1981, Volume: 7, Issue:4

    Topics: Animals; Antioxidants; Carnitine; Citric Acid Cycle; Creatine; Electron Transport; Energy Metabolism; Glycolysis; Humans; Mitochondria; Nucleosides; Orthomolecular Therapy; Rabbits; Rats; Thioctic Acid; Ubiquinone

1981
Effect of lipoic acid on redox state of coenzyme Q in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate.
    European journal of pharmacology, 1994, Feb-15, Volume: 266, Issue:3

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Ditiocarb; Dopamine; Frontal Lobe; Hippocampus; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; NADH Dehydrogenase; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Thioctic Acid; Ubiquinone; Vitamin E

1994
Endogenous and exogenous regulation of redox-properties of coenzyme Q.
    Molecular aspects of medicine, 1997, Volume: 18 Suppl

    Topics: Antioxidants; Electron Spin Resonance Spectroscopy; Lipid Peroxidation; Lipoproteins, LDL; Liposomes; Oxidation-Reduction; Oxidative Stress; Peroxides; Photolysis; Thioctic Acid; Ubiquinone

1997
Dihydrolipoic acid maintains ubiquinone in the antioxidant active form by two-electron reduction of ubiquinone and one-electron reduction of ubisemiquinone.
    Archives of biochemistry and biophysics, 1999, Mar-01, Volume: 363, Issue:1

    Topics: Animals; Antioxidants; Coenzymes; Cold Temperature; Cytoprotection; Electron Spin Resonance Spectroscopy; Electrons; Hydrogen-Ion Concentration; Mitochondria, Liver; Oxidation-Reduction; Rats; Spectrophotometry, Ultraviolet; Spectrum Analysis; Thioctic Acid; Ubiquinone

1999
Activity of alpha-lipoic acid in the protection against oxidative stress in skin.
    Current problems in dermatology, 2001, Volume: 29

    Topics: Antioxidants; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Humans; Keratinocytes; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Solubility; Thioctic Acid; Ubiquinone; Ultraviolet Rays; Vitamin E

2001
Coenzyme Q10, vitamin E, and dihydrothioctic acid cooperatively prevent diene conjugation in isolated low-density lipoprotein.
    Antioxidants & redox signaling, 2000,Summer, Volume: 2, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Coenzymes; Copper; Humans; Ions; Lipoproteins, LDL; Male; Middle Aged; Models, Biological; Molsidomine; Nitric Oxide Donors; Oxygen; Protein Binding; Thioctic Acid; Time Factors; Ubiquinone; Vitamin E

2000
Dietary modulation of age-related changes in cerebral pro-oxidant status.
    Neurochemistry international, 2002, Volume: 40, Issue:2

    Topics: Aging; alpha-Tocopherol; Analysis of Variance; Animals; Antioxidants; Cerebral Cortex; Diet; Glutathione; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mitochondria; Motor Activity; Nitric Oxide Synthase; Reactive Oxygen Species; Synaptosomes; Thioctic Acid; Ubiquinone

2002
Neuronal death in the rat hippocampus in experimental diabetes and cerebral ischaemia treated with antioxidants.
    Folia neuropathologica, 2001, Volume: 39, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Brain Ischemia; Caspase 3; Caspases; Cell Count; Coenzymes; Dentate Gyrus; Diabetes Mellitus, Experimental; Free Radicals; Hippocampus; Male; Rats; Rats, Wistar; Thioctic Acid; Ubiquinone

2001
Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.
    Chemico-biological interactions, 2002, Aug-15, Volume: 140, Issue:3

    Topics: Dihydrolipoamide Dehydrogenase; Guanine; NADP; Nitrogen Oxides; Oxidation-Reduction; Reactive Nitrogen Species; Thioctic Acid; Tyrosine; Ubiquinone; Xanthines

2002
Antioxidants effectively prevent oxidation-induced protein damage in OLN 93 cells.
    Archives of biochemistry and biophysics, 2004, Jan-01, Volume: 421, Issue:1

    Topics: Animals; Antioxidants; Brain; Cell Line; Cell Survival; Coenzymes; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Hydrogen Peroxide; Immunoblotting; Mitochondria; Mitochondrial Proteins; Oligodendroglia; Oxidative Stress; Paraquat; Rats; Superoxide Dismutase; Thioctic Acid; Trichloroacetic Acid; Ubiquinone

2004
The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice.
    Free radical biology & medicine, 2004, Apr-15, Volume: 36, Issue:8

    Topics: Algorithms; Animals; Antioxidants; Body Weight; Caloric Restriction; Coenzymes; Complement System Proteins; Cytosol; Dietary Supplements; Extracellular Matrix; Free Radicals; Gene Expression Regulation; Longevity; Major Histocompatibility Complex; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Myocardium; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Oxidative Stress; Oxygen; Phosphorylation; RNA; Thioctic Acid; Time Factors; Transcription, Genetic; Ubiquinone

2004
Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Acetyltransferases; Animals; Benzoquinones; Binding, Competitive; Cattle; Cells, Cultured; Dihydrolipoyllysine-Residue Acetyltransferase; Humans; Immunoblotting; Islets of Langerhans; Ketoglutarate Dehydrogenase Complex; Mitochondria; Precipitin Tests; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Sulfhydryl Compounds; Swine; Thioctic Acid; Ubiquinone

2004
Response of the senescent heart to stress: clinical therapeutic strategies and quest for mitochondrial predictors of biological age.
    Annals of the New York Academy of Sciences, 2004, Volume: 1019

    Topics: Aging; Clinical Trials as Topic; Coenzymes; DNA, Mitochondrial; Exercise; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Heart; Humans; Mitochondria; Models, Biological; Multivariate Analysis; Myocardium; Orotic Acid; Surveys and Questionnaires; Thioctic Acid; Thoracic Surgery; Time Factors; Ubiquinone

2004
Effects of antioxidants coenzyme Q10 and lipoic acid on interleukin-1 beta-mediated inhibition of glucose-stimulated insulin release from cultured mouse pancreatic islets.
    Immunopharmacology and immunotoxicology, 2005, Volume: 27, Issue:1

    Topics: Animals; Antioxidants; Cells, Cultured; Coenzymes; Female; Glucose; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Thioctic Acid; Ubiquinone

2005
Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents.
    International journal of radiation oncology, biology, physics, 2006, Apr-01, Volume: 64, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cells, Cultured; Coenzymes; Epithelial Cells; Fluoresceins; Humans; Oxidative Stress; Radiation Protection; Selenomethionine; Thioctic Acid; Tocopherols; Ubiquinone; Vitamin E

2006
Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia.
    Urology, 2008, Volume: 72, Issue:1

    Topics: Animals; Antioxidants; Carbachol; Electric Stimulation; Electron Transport Chain Complex Proteins; In Vitro Techniques; Ischemia; Male; Muscle Contraction; Potassium Chloride; Rabbits; Thioctic Acid; Ubiquinone; Urinary Bladder

2008
The beneficial effect of coenzyme Q10 and lipoic acid on obstructive bladder dysfunction in the rabbit.
    The Journal of urology, 2008, Volume: 180, Issue:5

    Topics: Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Immunohistochemistry; Male; Muscle Contraction; Muscle, Smooth; Probability; Rabbits; Random Allocation; Sensitivity and Specificity; Thioctic Acid; Ubiquinone; Urinary Bladder Neck Obstruction

2008
Coenzyme Q(10) and alpha-lipoic acid supplementation in diabetic rats: conduction velocity distributions.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:5

    Topics: Action Potentials; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Injections, Intraperitoneal; Kinetics; Male; Neural Conduction; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thioctic Acid; Ubiquinone

2008
The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients.
    Fertility and sterility, 2010, Volume: 93, Issue:1

    Topics: Age Factors; Aging; Animals; Dietary Supplements; DNA, Mitochondrial; Energy Metabolism; Female; Humans; Infertility, Female; Mice; Mice, Inbred ICR; Mitochondria; Oocytes; Pregnancy; Resveratrol; Stilbenes; Thioctic Acid; Ubiquinone

2010
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Alkanes; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Drug Design; Electron Transport; Ethylamines; Humans; Ligands; Protein Binding; Reactive Oxygen Species; Submitochondrial Particles; Thioctic Acid; Ubiquinone

2009
Mitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineurs.
    Neurology, 2010, Jan-12, Volume: 74, Issue:2

    Topics: Brain Diseases, Metabolic; Chronic Disease; Disease Progression; DNA, Mitochondrial; Genetic Predisposition to Disease; Haplotypes; Humans; Migraine Disorders; Mitochondrial Diseases; Riboflavin; Thioctic Acid; Ubiquinone; Vitamin B Complex

2010
Differential effects of coenzyme Q10 and α-lipoic acid on two models of in vitro oxidative damage to the rabbit urinary bladder.
    International urology and nephrology, 2011, Volume: 43, Issue:1

    Topics: Animals; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Follow-Up Studies; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Oxidative Stress; Rabbits; Reperfusion Injury; Thioctic Acid; Ubiquinone; Urinary Bladder Neck Obstruction; Vitamins

2011
Neuropharmacological effects of lipoic acid and ubiquinone on δ-aminolevulinic dehydratase, Na(+) , K(+) -ATPase, and Mg(2+) -ATPase activities in rat hippocampus after pilocarpine-induced seizures.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:2

    Topics: Animals; Antioxidants; Ca(2+) Mg(2+)-ATPase; Disease Models, Animal; Hippocampus; Male; Oxidative Stress; Pilocarpine; Porphobilinogen Synthase; Rats; Rats, Wistar; Seizures; Sodium-Potassium-Exchanging ATPase; Thioctic Acid; Ubiquinone

2011
Neuropharmacological effects of lipoic acid and ubiquinone on the mRNA level of interleukin-1β and acetylcholinesterase activity in rat hippocampus after seizures.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:3

    Topics: Acetylcholinesterase; Animals; Hippocampus; Interleukin-1beta; Male; Pilocarpine; Rats; Rats, Wistar; RNA, Messenger; Seizures; Thioctic Acid; Ubiquinone

2011
The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion.
    Molecular and cellular biochemistry, 2011, Volume: 355, Issue:1-2

    Topics: Animals; Antioxidants; Fatty Acids, Nonesterified; Ischemia; Lipid Peroxidation; Male; Malondialdehyde; Mucous Membrane; Muscle, Smooth; Organ Size; Phospholipases A2; Phospholipids; Rabbits; Reperfusion Injury; Thioctic Acid; Ubiquinone; Urinary Bladder

2011
Direct analysis of carbohydrates in animal plasma by ion chromatography coupled with mass spectrometry and pulsed amperometric detection for use as a non-invasive diagnostic tool.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Dec-01, Volume: 879, Issue:31

    Topics: Animals; Blood Glucose; Chickens; Chromatography, Ion Exchange; Diagnostic Techniques and Procedures; Dogs; Glucose; Intestinal Absorption; Lactulose; Mannitol; Meloxicam; Oxidation-Reduction; Reproducibility of Results; Tandem Mass Spectrometry; Thiazines; Thiazoles; Thioctic Acid; Ubiquinone

2011
A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Cell Differentiation; Cell Survival; Cells, Cultured; DNA-Binding Proteins; Energy Metabolism; Gene Expression Regulation; Glutathione; High Mobility Group Proteins; Mice; Models, Biological; Muscle Cells; Muscle, Skeletal; NF-E2-Related Factor 2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; RNA, Messenger; Stress, Physiological; Thioctic Acid; Trans-Activators; Transcription Factors; Ubiquinone

2012
Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Antioxidants; Dietary Supplements; Female; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Skeletal; Physical Exertion; Thioctic Acid; Ubiquinone; Vitamin E

2013
Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients.
    Free radical biology & medicine, 2014, Volume: 69

    Topics: Acetylcarnitine; Animals; Mitochondria; Mitochondrial Turnover; Muscular Atrophy; Muscular Disorders, Atrophic; Oxidative Stress; Phenylethyl Alcohol; Rats; Signal Transduction; Thioctic Acid; Ubiquinone

2014
Mitochondrial dysfunction and chronic disease: treatment with natural supplements.
    Alternative therapies in health and medicine, 2014,Winter, Volume: 20 Suppl 1

    Topics: Carnitine; Dietary Supplements; Fatigue Syndrome, Chronic; Humans; Mitochondrial Diseases; NAD; Thioctic Acid; Ubiquinone

2014
Amelioration of behavioural, biochemical, and neurophysiological deficits by combination of monosodium glutamate with resveratrol/alpha-lipoic acid/coenzyme Q10 in rat model of cisplatin-induced peripheral neuropathy.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Animals; Behavior, Animal; Catalase; Disease Models, Animal; Drug Therapy, Combination; Glutathione; Lipid Peroxidation; Neural Conduction; Neuroprotective Agents; Peripheral Nervous System Diseases; Psychomotor Performance; Rats; Resveratrol; Sciatic Neuropathy; Sodium Glutamate; Stilbenes; Thioctic Acid; Ubiquinone

2013
Development and characterisation of a novel chitosan-coated antioxidant liposome containing both coenzyme Q10 and alpha-lipoic acid.
    Journal of microencapsulation, 2015, Volume: 32, Issue:2

    Topics: Administration, Cutaneous; Animals; Chitosan; Coated Materials, Biocompatible; Free Radical Scavengers; Liposomes; Rabbits; Skin Absorption; Thioctic Acid; Ubiquinone

2015
Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.
    American journal of human genetics, 2015, Nov-05, Volume: 97, Issue:5

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Calcium-Binding Proteins; Child, Preschool; DNA Methylation; Female; Humans; Male; Mitochondrial Diseases; Molecular Sequence Data; Muscle Weakness; Mutation; Pedigree; Prognosis; RNA Stability; S-Adenosylmethionine; Sequence Homology, Amino Acid; Thioctic Acid; Ubiquinone

2015
POTENTIAL ADMINISTRATION OF LIPOIC ACID AND COENZYME Q AGAINST ADIPOGENSIS: TARGET FOR WEIGHT REDUCTION.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017, Volume: 14, Issue:1

    Topics: Adipogenesis; Animals; Anti-Obesity Agents; Humans; Lipoprotein Lipase; Male; Obesity; Rats; Thioctic Acid; Triglycerides; Ubiquinone; Weight Loss

2017
In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles.
    Molecules (Basel, Switzerland), 2017, May-27, Volume: 22, Issue:6

    Topics: Antioxidants; Lipids; Nanoparticles; Particle Size; Thioctic Acid; Ubiquinone

2017
In vitro evaluation of chitosan-coated liposome containing both coenzyme Q10 and alpha-lipoic acid: Cytotoxicity, antioxidant activity, and antimicrobial activity.
    Journal of cosmetic dermatology, 2018, Volume: 17, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cell Survival; Cells, Cultured; Chitosan; Escherichia coli; Fibroblasts; Hydrogen Peroxide; Liposomes; Mice; Phenols; Plant Extracts; Staphylococcus aureus; Thioctic Acid; Ubiquinone

2018
Nutritional support in mitochondrial diseases: the state of the art.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:13

    Topics: Arginine; Deglutition Disorders; Diet, High-Fat; Energy Metabolism; Humans; Mitochondria; Mitochondrial Diseases; Nutritional Support; Thioctic Acid; Ubiquinone

2018
Alpha-lipoic acid and coenzyme Q10 combination ameliorates experimental diabetic neuropathy by modulating oxidative stress and apoptosis.
    Life sciences, 2019, Jan-01, Volume: 216

    Topics: Administration, Oral; Animals; Apoptosis; Biomarkers; Blotting, Western; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Thioctic Acid; Ubiquinone; Uncoupling Protein 2

2019
A proof of concept 'phase zero' study of neurodevelopment using brain organoid models with Vis/near-infrared spectroscopy and electrophysiology.
    Scientific reports, 2020, 12-02, Volume: 10, Issue:1

    Topics: Acetylcarnitine; Brain; Case-Control Studies; Cell Line; Choline; Electron Transport Complex IV; Electrophysiology; Female; Humans; Induced Pluripotent Stem Cells; Male; Mitochondria; Organoids; Proof of Concept Study; Schizophrenia; Spectroscopy, Near-Infrared; Thioctic Acid; Ubiquinone

2020