thioctic acid and pyruvic acid

thioctic acid has been researched along with pyruvic acid in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199020 (51.28)18.7374
1990's4 (10.26)18.2507
2000's10 (25.64)29.6817
2010's5 (12.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bassendine, MF; Fussey, SP; James, OF; Yeaman, SJ1
De Marcucci, OG; Hodgson, JA; Lindsay, JG1
Aitken, A; Bradford, AP; Howell, S; James, LA; Yeaman, SJ1
Danson, MJ; Hale, G; Perham, RN1
Frey, PA1
Butwell, NB; Malloy, CR; Sherry, AD; Sumegi, B1
Lindsay, JG; Miller, C; Sanderson, SJ1
Bashan, N; Gutman, A; Khamaisi, M; Potashnik, R; Rudich, A; Tritschler, HJ1
Morkunaite, S; Saris, NE; Teplova, VV1
Curic, M; de Richelieu, M; Henriksen, CM; Jochumsen, KV; Nilsson, D; Villadsen, J1
Leaver, CJ; Millar, AH1
Lang, HJ; Obrosova, IG; Stevens, MJ1
Andersson, LA; Baker, JC; Cole, AB; Gong, X; Li, L; Liu, S; Peng, T; Ravindran, S; Robben, PM; Roche, TE; Yan, X1
DEBUSK, BG; REED, LJ2
SEAMAN, GR1
FISCHER, GL1
HELLERMAN, L; REISS, OK1
EISFELD, G; JULICH, H; MAMPEL, E1
REISS, OK1
LECOQ, R1
BARKER, HA; KLINE, L; PINE, L1
LEACH, FR; WILSON, DD; WINTER, BA1
DEIBEL, RH; NIVEN, CF1
KONO, H1
DEITRICH, RA; HELLERMAN, L1
HAAF, AS; WITTENBERGER, CL1
BRAVO, M; ORREGO, H; WALSHE, JM1
Amani, Z; Buse, MG; Locher, M; McMillan, JM; Walgren, JL1
Korotchkina, LG; Patel, MS; Sidhu, S1
Kim, HJ; Kim, JM; Kim, M; Lee, KW; Park, JH; Sung, JJ1
Daniel, H; Nickel, A; Wenzel, U1
Chinnakannu, P; Sethumadhavan, S1
Barrera, D; Maldonado, PD; Medina-Campos, ON; Mendoza-PatiƱo, N; Pedraza-Chaverri, J; Rocha, D; Segoviano-Murillo, S1
Breslow, R; Zhao, H1
Cronan, JE; Hassan, BH1
Herzig, S; Kunji, ER; Martinou, JC; Montessuit, S; Raemy, E; Veuthey, JL; Westermann, B; Zamboni, N1
Hou, X; Huang, W; Li, Y; Luo, L; Miao, Z; Qi, Q; Shen, Y; Wang, F; Wang, H; Wang, L; Wang, Y; Wang, Z; Yang, S; Zhang, Y1
Bayer, SB; Hampton, MB; Winterbourn, CC1

Reviews

1 review(s) available for thioctic acid and pyruvic acid

ArticleYear
Mechanism of coupled electron and group transfer in Escherichia coli pyruvate dehydrogenase.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylation; Binding Sites; Chemical Phenomena; Chemistry; Coenzyme A; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Molecular Weight; NAD; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Spectrophotometry; Thiamine Pyrophosphate; Thioctic Acid

1982

Other Studies

38 other study(ies) available for thioctic acid and pyruvic acid

ArticleYear
Characterisation of the reactivity of autoantibodies in primary biliary cirrhosis.
    FEBS letters, 1989, Mar-27, Volume: 246, Issue:1-2

    Topics: Acetylation; Antigens; Autoantibodies; Blotting, Western; Epitopes; Escherichia coli; Ethylmaleimide; Humans; Liver Cirrhosis, Biliary; Molecular Weight; Peptide Fragments; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Thioctic Acid; Trypsin

1989
Lipoic acid is the site of substrate-dependent acetylation of component X in ox heart pyruvate dehydrogenase multienzyme complex.
    European journal of biochemistry, 1986, Aug-01, Volume: 158, Issue:3

    Topics: Acetylation; Animals; Carbon Radioisotopes; Cattle; Ethylmaleimide; Male; Myocardium; Peptides; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1986
Primary structure around the lipoate-attachment site on the E2 component of bovine heart pyruvate dehydrogenase complex.
    The Biochemical journal, 1987, Aug-01, Volume: 245, Issue:3

    Topics: Acetylation; Amino Acid Sequence; Animals; Cattle; Ethylmaleimide; Mass Spectrometry; Molecular Sequence Data; Myocardium; Peptide Fragments; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1987
The role of lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli.
    The Biochemical journal, 1981, Dec-01, Volume: 199, Issue:3

    Topics: Acetyl Coenzyme A; Acetylation; Escherichia coli; Ethylmaleimide; NAD; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1981
Lipoamide influences substrate selection in post-ischaemic perfused rat hearts.
    The Biochemical journal, 1994, Jan-01, Volume: 297 ( Pt 1)

    Topics: Acetates; Acetylation; Animals; Aspartic Acid; Binding, Competitive; Carbon Isotopes; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thioctic Acid

1994
Stoichiometry, organisation and catalytic function of protein X of the pyruvate dehydrogenase complex from bovine heart.
    European journal of biochemistry, 1996, Feb-15, Volume: 236, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Cattle; Collagenases; Cross-Linking Reagents; Myocardium; NAD; Peptides; Protein Conformation; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1996
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Fasting; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Hypoglycemia; Liver; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thioctic Acid

1999
Mechanism of dihydrolipoate stimulation of the mitochondrial permeability transition: effect of different respiratory substrates.
    IUBMB life, 2000, Volume: 49, Issue:3

    Topics: Animals; Antioxidants; Calcium; Dose-Response Relationship, Drug; Glutathione; Ketoglutaric Acids; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Pyridines; Pyruvic Acid; Rats; Reactive Oxygen Species; Spectrometry, Fluorescence; Thioctic Acid; Time Factors

2000
Glucose/citrate cometabolism in Lactococcus lactis subsp. lactis biovar diacetylactis with impaired alpha-acetolactate decarboxylase.
    Metabolic engineering, 1999, Volume: 1, Issue:4

    Topics: Biotechnology; Carboxy-Lyases; Citric Acid; Diacetyl; Fermentation; Glucose; Lactococcus lactis; Mutation; Oxidation-Reduction; Pyruvic Acid; Thioctic Acid

1999
The cytotoxic lipid peroxidation product, 4-hydroxy-2-nonenal, specifically inhibits decarboxylating dehydrogenases in the matrix of plant mitochondria.
    FEBS letters, 2000, Sep-15, Volume: 481, Issue:2

    Topics: Acyltransferases; Aldehydes; Amino Acid Oxidoreductases; Antibodies; Cell Respiration; Glycine Decarboxylase Complex H-Protein; Glycine Dehydrogenase (Decarboxylating); Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Kinetics; Lipid Peroxidation; Malate Dehydrogenase; Malates; Mitochondria; Molecular Weight; Oxidoreductases; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Solanum tuberosum; Succinic Acid; Thioctic Acid

2000
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
    Pharmacology, 2001, Volume: 62, Issue:3

    Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid

2001
Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.
    Archives of biochemistry and biophysics, 2001, Feb-15, Volume: 386, Issue:2

    Topics: Acetylation; Acetyltransferases; Animals; Cattle; Circular Dichroism; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Humans; Kinetics; Models, Molecular; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Thermodynamics; Thiamine Pyrophosphate; Thioctic Acid

2001
A conjugate of alpha-lipoic acid required for oxidation of pyruvate and alpha-ketoglutarate by an Escherichia coli mutant.
    The Journal of biological chemistry, 1952, Volume: 199, Issue:2

    Topics: Acids; Escherichia coli; Keto Acids; Ketoglutaric Acids; Ketones; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Thioctic Acid

1952
Chemical nature of an alpha-lipoic acid conjugate required for oxidation of pyruvate and alpha-ketoglutarate by an Escherichia coli mutant.
    The Journal of biological chemistry, 1952, Volume: 199, Issue:2

    Topics: Acids; Escherichia coli; Ketoglutaric Acids; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Thioctic Acid

1952
Effect of thioctic acid on the incorporation of carbon dioxide into pyruvate.
    Journal of bacteriology, 1953, Volume: 65, Issue:6

    Topics: Acids; Carbon Dioxide; Pyruvates; Pyruvic Acid; Thioctic Acid

1953
Thioctic acid content and pyruvate oxidation in ethionine-damaged rat livers.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1955, Volume: 90, Issue:1

    Topics: Acids; Body Fluids; Ethionine; Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Thioctic Acid; Urine

1955
Pyruvate utilization in heart sarcosomes; inhibition by an arsenoso compound and reactivation by lipoic acid.
    The Journal of biological chemistry, 1958, Volume: 231, Issue:1

    Topics: Heart; Mitochondria, Muscle; Myocardium; Pyruvates; Pyruvic Acid; Thioctic Acid; Vitamins

1958
[Change of pyruvic acid level in blood by alpha-lipoic acid].
    Arztliche Forschung, 1958, Oct-10, Volume: 12, Issue:10

    Topics: Pyruvates; Pyruvic Acid; Thioctic Acid; Vitamin A; Vitamin K; Vitamins

1958
Pyruvate metabolism. II. Restoration of pyruvate utilization in heart sarcosomes by alpha-(+)-lipoic acid.
    The Journal of biological chemistry, 1958, Volume: 233, Issue:4

    Topics: Arsenicals; Heart; Humans; Lyases; Mitochondria, Muscle; Myocardium; Pyruvates; Pyruvic Acid; Thioctic Acid; Vitamin A; Vitamins

1958
[Comparative action of thioctic acid (lipoic acid) and glutathione on the plasma alkaline reserve of rabbits and on experimental pyruvic acid poisoning].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1958, Oct-20, Volume: 247, Issue:16

    Topics: Acid-Base Equilibrium; Animals; Glutathione; Plasma; Pyruvates; Pyruvic Acid; Rabbits; Thioctic Acid; Vitamin A; Vitamin K; Vitamins

1958
METABOLIC ROLE OF THE BR FACTOR IN BUTYRIBACTERIUM RETTGERI.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Acetates; Carbohydrate Metabolism; Carbon Dioxide; Eubacterium; Fermentation; Glucose; Lactates; Lactic Acid; Manometry; Pyruvates; Pyruvic Acid; Research; Thioctic Acid

1963
ROLE OF LIPOIC ACID IN PYRUVATE TRANSPORT.
    Journal of bacteriology, 1964, Volume: 87

    Topics: Enterococcus faecalis; Ion Transport; Metabolism; Pyruvates; Pyruvic Acid; Research; Thioctic Acid

1964
PYRUVATE FERMENTATION BY STREPTOCOCCUS FAECALIS.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Acetates; Acetoin; Carbon Dioxide; Enterococcus faecalis; Fermentation; Formates; Lactates; Metabolism; Pharmacology; Pyruvates; Pyruvic Acid; Research; Thiamine; Thioctic Acid

1964
[CLINICAL RESEARCH ON PYRUVIC ACID METABOLISM IN LIVER DISEASES. II. EFFECTS OF DIFFERENT DRUGS ON THE PYRUVIC ACID BLOOD LEVEL IN LIVER DISEASES].
    Acta medicinae Okayama, 1964, Volume: 18

    Topics: Adrenal Cortex Hormones; Asparagine; Blood Chemical Analysis; Glucose; Hepatitis; Hepatitis A; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Magnesium; Pharmacology; Potassium; Pyruvates; Pyruvic Acid; Sorbitol; Thiamine; Thioctic Acid

1964
PYRUVATE METABOLISM. V. PYRUVATE UTILIZATION BY MITOCHONDRIA OF RAT BRAIN.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine Nucleotides; Antimetabolites; Brain; Butyrates; Citrates; Citric Acid Cycle; Cytochromes; Fumarates; Ketoglutaric Acids; Magnesium; Metabolism; Mitochondria; Phosphates; Pyruvates; Pyruvic Acid; Rats; Research; Succinates; Thioctic Acid

1964
LACTATE-DEGRADING SYSTEM IN BUTYRIBACTERIUM RETTGERI SUBJECT TO GLUCOSE REPRESSION.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Culture Media; Eubacterium; Fructose; Glucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Metabolism; NAD; Oxidation-Reduction; Oxidoreductases; Pyruvates; Pyruvic Acid; Research; Thioctic Acid; United States

1964
[Lactic and pyruvic acids in liver cirrhosis before and after the oral administration of glucose. Influence of thioctic acid on such acids].
    Revista medica de Chile, 1959, Volume: 87

    Topics: Administration, Oral; Glucose; Lactates; Liver Cirrhosis; Pyruvates; Pyruvic Acid; Thioctic Acid

1959
Effect of R(+)alpha-lipoic acid on pyruvate metabolism and fatty acid oxidation in rat hepatocytes.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:2

    Topics: Animals; Antioxidants; Carbon Dioxide; Cells, Cultured; Decarboxylation; Fatty Acids; Glucose; Hepatocytes; In Vitro Techniques; Male; Oxidation-Reduction; Palmitic Acid; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Long-Evans; Thioctic Acid

2004
R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase.
    Free radical research, 2004, Volume: 38, Issue:10

    Topics: Acetyltransferases; Binding Sites; Dihydrolipoyllysine-Residue Acetyltransferase; Glucose; Humans; Lactic Acid; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Thioctic Acid

2004
Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity.
    Neuroreport, 2005, Apr-25, Volume: 16, Issue:6

    Topics: Amyotrophic Lateral Sclerosis; Cell Death; Cell Line, Tumor; Copper; Energy Metabolism; Free Radical Scavengers; Humans; Hybrid Cells; Motor Neurons; Mutation; Neuroblastoma; Neuroprotective Agents; Pyruvic Acid; Superoxide Dismutase; Superoxide Dismutase-1; Thiamine; Thioctic Acid

2005
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:2

    Topics: Angiogenesis Inhibitors; Apoptosis; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytosol; DNA Fragmentation; Humans; Immunoblotting; Lactates; Lactic Acid; Mitochondria; Nitrobenzoates; Oxidative Stress; Oxygen; Pyruvic Acid; Reactive Oxygen Species; Superoxides; Thioctic Acid; Time Factors

2005
L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2006, Volume: 61, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Carnitine; Cell Respiration; Glutamic Acid; Hydroxybutyrates; Malates; Male; Mitochondria, Heart; Pyruvic Acid; Rats; Rats, Wistar; Succinic Acid; Thioctic Acid

2006
S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:10

    Topics: Animals; Cell Survival; Cysteine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; LLC-PK1 Cells; Potassium Dichromate; Pyruvic Acid; Reactive Oxygen Species; Superoxides; Swine; Thioctic Acid; Thiourea

2007
A mimic of the pyruvate dehydrogenase complex.
    Bioorganic & medicinal chemistry letters, 2010, Oct-15, Volume: 20, Issue:20

    Topics: Acetanilides; Aniline Compounds; Catalysis; Decarboxylation; Polyethyleneimine; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Sulfides; Thiazoles; Thioctic Acid

2010
Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism.
    The Journal of biological chemistry, 2011, Mar-11, Volume: 286, Issue:10

    Topics: Acyltransferases; Aerobiosis; Bacterial Proteins; Escherichia coli K12; Escherichia coli Proteins; Ketoglutaric Acids; Oxidoreductases; Pyruvic Acid; Thioctic Acid

2011
Identification and functional expression of the mitochondrial pyruvate carrier.
    Science (New York, N.Y.), 2012, Jul-06, Volume: 337, Issue:6090

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Biosynthetic Pathways; Culture Media; Lactococcus lactis; Leucine; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Molecular Sequence Data; Monocarboxylic Acid Transporters; Proprotein Convertase 1; Proprotein Convertase 2; Pyruvic Acid; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thioctic Acid; Valine

2012
Scavenging of blood glutamate for enhancing brain-to-blood glutamate efflux.
    Molecular medicine reports, 2014, Volume: 9, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Free Radical Scavengers; Glutamic Acid; Oxaloacetic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thioctic Acid

2014
Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention.
    Transfusion, 2015, Volume: 55, Issue:8

    Topics: Acetylcysteine; Adenine; Adolescent; Adult; Aged; Antioxidants; Blood Preservation; Buffers; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Female; Glucose; Glutathione; Humans; Hydrogen Peroxide; Inosine; Male; Middle Aged; Oxidation-Reduction; Peroxiredoxins; Phosphates; Pyruvic Acid; Solutions; Sulfhydryl Compounds; Thioctic Acid; Young Adult

2015