thioctic acid and nad

thioctic acid has been researched along with nad in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199060 (60.61)18.7374
1990's17 (17.17)18.2507
2000's15 (15.15)29.6817
2010's5 (5.05)24.3611
2020's2 (2.02)2.80

Authors

AuthorsStudies
Hall, FF; Linn, TC; Little, GH; Pelley, JW1
Strating, M; Visser, J1
Brown, JP; Perham, RN1
Bridges, BJ; Cooper, RH; Denton, RM; Randle, PJ; Walsh, DA1
Cate, RL; Roche, TE2
Shih, JC1
Kagan, VE; Khan, S; Packer, L; Powell, R; Serbinova, E; Shvedova, A; Swanson, C1
Blanchard, JS; Leichus, BN1
Buneeva, OA; Bunik, VI; Gomazkova, VS1
Andreesen, JR; Freudenberg, W1
Sahlman, L; Williams, CH1
Rahmatullah, M; Roche, TE1
Heine, HG; Richarme, G1
Richarme, G1
Huang, RR; Spector, A; Wang, RR; Yan, GZ1
Bourguignon, J; Douce, R; Neuburger, M1
Hummel, BC; Sawada, K; Walfish, PG1
Rajacic, Z; Thölen, H; Zimmerli, W1
Moormann, JG1
Williams, CH1
Colombi, A; Engelhart, G; Thölen, H1
Hamada, M; Hayakawa, T; Hirashima, M; Ide, S; Koike, M; Okabe, K1
Hayakawa, T; Ide, S; Koike, M; Okabe, K1
Marchant, KA; Pappas, BC; Pappas, SP1
Barbier, P; Caroli, J; Hecht, Y1
Bigler, F; Colombi, A; Duckert, F; Huber, F; Müller, HR; Thölen, H1
Benhamou, JP; Caroli, J; Debray, C; Gaultier, M; Leger, L1
Skrede, S1
Leach, FR; Oh, YK1
Fukuyoshi, Y; Hayakawa, T; Kanzaki, T; Kitamura, T; Koike, K; Koike, M; Sakurai, Y; Suematsu, T1
Colombi, A; Huber, F; Thölen, H1
Ostrowski, W; Steczko, J; Zak, Z1
Bani, G1
Poulsen, LL; Wedding, RT1
Rozanov, AIa1
Beychok, S; Brady, AH1
Ziegler, K1
Correa, W; Kinon, BJ; Kosower, EM; Kosower, NS1
Hamada, M; Koike, K; Koike, M; Otsuka, KI; Suematsu, T; Tanaka, N1
Elsas, LJ; Pask, BA; Perl, DP; Truster, S; Wheeler, FB1
Henning, U; Hoehn, B; Vogel, O1
Battelli, MG; Lorenzoni, E; Stripe, F1
Burgett, MW; Reed, LJ; Tsai, CS1
Mordhorst, R; Thölen, H1
McGarry, JD1
Leclerc, M1
Ragan, CI; Tottmar, SO1
Guha, SR; Mitra, C1
Goswami, A; Rosenberg, IN1
Cronshaw, AD; Jocelyn, PC1
Tsai, CS1
Danson, MJ; Hale, G; Perham, RN1
Frey, PA1
Becker, DM; Kark, RA; Knipprath, WG; Nissenson, C; Perlman, SL1
Liu, TC; Patel, MS; Vettakkorumakankav, NN1
Bisswanger, H; Borbe, HO; Bunik, V; Follmann, H; Loeffelhardt, S; Shoubnikova, A1
Guest, JR; Maeda-Yorita, K; Massey, V; Russell, GC; Williams, CH1
Lubbers, F; Neijssel, OM; Snoep, JL; Teixeira de Mattos, MJ; van Bommel, M1
Hol, WG; Kalk, KH; Mattevi, A; Obmolova, G; van Berkel, WJ1
Bast, A; Biewenga, GP; Dorstijn, MA; Haenen, GR; Verhagen, JV1
Lindsay, JG; Miller, C; Sanderson, SJ1
Handelman, G; Konishi, T; Mathur, VV; Matsugo, S; Packer, L; Tritschler, HJ1
Richter, C; Schweizer, M1
Han, D; Handelman, GJ; Haramaki, N; Packer, L; Tritschler, HJ1
Packer, L; Roy, S; Sen, CK; Tritschler, HJ1
Akiba, S; Konishi, T; Matsugo, S; Packer, L1
Cao, X; Greene, DA; Obrosova, I; Stevens, MJ1
Fischer, GM; Gallyas, F; Kispal, G; Sumegi, B; Szabados, E1
Balabolkin, MI; Kreminskaia, VM1
Courteau, J; Kocsis-Bédard, S; Niyonsenga, T; Paquette, B; Thibodeau, PA1
Lang, HJ; Obrosova, IG; Stevens, MJ1
Bryk, R; Erdjument-Bromage, H; Lima, CD; Nathan, C; Tempst, P1
Jones, W; Li, X; May, JM; Perriott, L; Qu, ZC; Whitesell, RR1
Bunik, VI; Sievers, C1
Argyrou, A; Blanchard, JS; Palfey, BA1
Argyrou, A; Blanchard, JS; Palfey, BA; Sun, G1
Bunik, VI1
MOR, F1
BIGLER, F; HEUSLER, A; STAUB, H; THOELEN, H1
WORTMAN, B1
DUNCAN, IW; EKSTRAND, V; SCOTT, EM1
BIGLER, F; THOELEN, H1
CHATTERJEE, SK; GAL, EM; MARSHALL, FD1
HAAF, AS; WITTENBERGER, CL1
BALDWIN, RL; MILLIGAN, LP1
Butterfield, DA; Pocernich, CB1
Bao, H; Hiromasa, Y; Kasten, SA; Roche, TE; Yan, X1
Brautigam, CA; Chuang, DT; Chuang, JL; Machius, M; Tomchick, DR1
Forster, MJ; Prokai, L; Shu, H; Yan, LJ; Yang, SH1
May, JM; Nelson, DJ; Qu, ZC1
Håkansson, AP; Smith, AW1
Arango, N; Bryk, R; Lima, CD; Nathan, C; Park, YH; Patel, MS; Venugopal, A; Warren, JD1
Nicolson, GL1
Fukamichi, T; Nishimoto, E1
Krishnan, C; Sarangi, A1
Lian, J; Zhao, H1
Chandra, P; Chiranjivi, AK; Dubey, VK; Prakash, J; Saha, G1
Hargreaves, IP; Mantle, D1

Reviews

3 review(s) available for thioctic acid and nad

ArticleYear
Mechanism of coupled electron and group transfer in Escherichia coli pyruvate dehydrogenase.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylation; Binding Sites; Chemical Phenomena; Chemistry; Coenzyme A; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Molecular Weight; NAD; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Spectrophotometry; Thiamine Pyrophosphate; Thioctic Acid

1982
2-Oxo acid dehydrogenase complexes in redox regulation.
    European journal of biochemistry, 2003, Volume: 270, Issue:6

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Disulfides; Ketone Oxidoreductases; Multienzyme Complexes; NAD; Oxidation-Reduction; Sulfhydryl Compounds; Superoxides; Thioctic Acid; Thioredoxins

2003
Mitochondrial Dysfunction and Neurodegenerative Disorders: Role of Nutritional Supplementation.
    International journal of molecular sciences, 2022, Oct-20, Volume: 23, Issue:20

    Topics: Adenosine Triphosphate; Carnitine; Dietary Supplements; Humans; Mitochondria; Multiple System Atrophy; NAD; Thioctic Acid; Vitamin D; Vitamins

2022

Trials

1 trial(s) available for thioctic acid and nad

ArticleYear
[Influence of coenzyme A, nicotinamide adenine dinucleotide (NAD), alpha-lipoic acid and cocarboxylase on acute hepatitis (double blind experiment)].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1969, Volume: 2, Issue:2

    Topics: Adenosine Triphosphate; Alanine Transaminase; Alkaline Phosphatase; Ammonia; Aspartate Aminotransferases; Bilirubin; Blood Coagulation Factors; Blood Proteins; Clinical Trials as Topic; Coenzyme A; Glucose; Glycols; Hepatitis A; Humans; Ketones; Lactates; NAD; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1969

Other Studies

95 other study(ies) available for thioctic acid and nad

ArticleYear
Lipoamide dehydrogenase in serum: a preliminary report.
    Clinical chemistry, 1976, Volume: 22, Issue:2

    Topics: Bilirubin; Buffers; Dihydrolipoamide Dehydrogenase; Evaluation Studies as Topic; Humans; Hydrogen-Ion Concentration; NAD; Thioctic Acid

1976
Separation of lipoamide dehydrogenase isoenzymes by affinity chromatography.
    Biochimica et biophysica acta, 1975, Mar-28, Volume: 384, Issue:1

    Topics: Alkanes; Animals; Chromatography, Affinity; Dihydrolipoamide Dehydrogenase; Isoenzymes; Ligands; Myocardium; NAD; Osmolar Concentration; Protein Binding; Sepharose; Structure-Activity Relationship; Swine; Temperature; Thioctic Acid

1975
Selective inactivation of the transacylase components of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli.
    The Biochemical journal, 1976, May-01, Volume: 155, Issue:2

    Topics: Disulfides; Escherichia coli; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Maleimides; Models, Chemical; NAD; Nitrobenzenes; Pyruvate Dehydrogenase Complex; Pyruvates; Thioctic Acid

1976
The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation.
    The Biochemical journal, 1976, Jul-01, Volume: 157, Issue:1

    Topics: Acetaldehyde; Adenylyl Imidodiphosphate; Animals; Arsenic; Coenzyme A; Diphosphates; Edetic Acid; Guanosine Triphosphate; Kinetics; Myocardium; NAD; Pyruvate Dehydrogenase Complex; Thiamine Pyrophosphate; Thioctic Acid

1976
Evidence for lipoic acid mediated NADH and acetyl-CoA stimulation of liver and kidney pyruvate dehydrogenase kinase.
    Biochemical and biophysical research communications, 1976, Oct-18, Volume: 72, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Cattle; Coenzyme A; Dithiothreitol; Kidney; Kinetics; Liver; NAD; Organ Specificity; Oxidation-Reduction; Phosphotransferases; Pyruvate Dehydrogenase Complex; Species Specificity; Swine; Thioctic Acid

1976
A unifying mechanism for stimulation of mammalian pyruvate dehydrogenase(a) kinase by reduced nicotinamide adenine dinucleotide, dihydrolipoamide, acetyl coenzyme A, or pyruvate.
    The Journal of biological chemistry, 1978, Jan-25, Volume: 253, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Cattle; Dithiothreitol; Kidney; Kinetics; Mitochondria; Mitochondria, Liver; NAD; Osmolar Concentration; Protein Kinases; Pyruvate Dehydrogenase Complex; Pyruvates; Thioctic Acid

1978
Radial diffusion assay of lipoamide dehydrogenase and its use to assess riboflavin deficiency.
    Analytical biochemistry, 1978, Aug-15, Volume: 89, Issue:1

    Topics: Animals; Chickens; Diffusion; Dihydrolipoamide Dehydrogenase; Liver; NAD; Polyethylene Glycols; Riboflavin Deficiency; Sepharose; Thioctic Acid

1978
Dihydrolipoic acid--a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals.
    Biochemical pharmacology, 1992, Oct-20, Volume: 44, Issue:8

    Topics: Animals; Antioxidants; Ascorbic Acid; Azo Compounds; Chromans; Female; Free Radicals; Intracellular Membranes; Lipid Peroxidation; Liposomes; Microsomes, Liver; NAD; NADP; Nitriles; Oxidation-Reduction; Peroxides; Rats; Rats, Sprague-Dawley; Thioctic Acid

1992
Pig heart lipoamide dehydrogenase: solvent equilibrium and kinetic isotope effects.
    Biochemistry, 1992, Mar-31, Volume: 31, Issue:12

    Topics: Animals; Catalysis; Dihydrolipoamide Dehydrogenase; Disulfides; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Myocardium; NAD; Solvents; Substrate Specificity; Swine; Thioctic Acid

1992
Change in alpha-ketoglutarate dehydrogenase cooperative properties due to dihydrolipoate and NADH.
    FEBS letters, 1990, Aug-20, Volume: 269, Issue:1

    Topics: Allosteric Regulation; Animals; Columbidae; Diethyl Pyrocarbonate; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Macromolecular Substances; Muscles; NAD; Oxidation-Reduction; Protein Conformation; Sulfhydryl Compounds; Thioctic Acid

1990
Purification and partial characterization of the glycine decarboxylase multienzyme complex from Eubacterium acidaminophilum.
    Journal of bacteriology, 1989, Volume: 171, Issue:4

    Topics: Amino Acid Oxidoreductases; Aminomethyltransferase; Cross Reactions; Eubacterium; Glycine Dehydrogenase (Decarboxylating); Hydroxymethyl and Formyl Transferases; Kinetics; Multienzyme Complexes; NAD; Spectrum Analysis; Thioctic Acid; Transferases

1989
Lipoamide dehydrogenase from Escherichia coli. Steady-state kinetics of the physiological reaction.
    The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14

    Topics: Animals; Dihydrolipoamide Dehydrogenase; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Myocardium; NAD; Oxidation-Reduction; Phosphorylation; Spectrophotometry; Swine; Thioctic Acid

1989
Component requirements for NADH inhibition and spermine stimulation of pyruvate dehydrogenaseb phosphatase activity.
    The Journal of biological chemistry, 1988, Jun-15, Volume: 263, Issue:17

    Topics: Alkylation; Animals; Calcium; Cattle; Enzyme Activation; Ethylmaleimide; NAD; Phosphoprotein Phosphatases; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase; Spermine; Thioctic Acid

1988
Galactose- and maltose-stimulated lipoamide dehydrogenase activities related to the binding-protein-dependent transport of galactose and maltose in toluenized cells of Escherichia coli.
    European journal of biochemistry, 1986, Apr-15, Volume: 156, Issue:2

    Topics: ATP-Binding Cassette Transporters; Biological Transport; Calcium-Binding Proteins; Carrier Proteins; Dihydrolipoamide Dehydrogenase; Edetic Acid; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Galactose; Genes, Bacterial; Maltose; Maltose-Binding Proteins; Monosaccharide Transport Proteins; Mutation; NAD; Operon; Periplasmic Binding Proteins; Thioctic Acid; Toluene

1986
[Reconstitution of high-affinity galactose transport of Salmonella typhimurium in proteoliposomes: energization by lipoamide and NAD or by the membrane potential; inhibition by ATP].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1987, Volume: 305, Issue:3

    Topics: Adenosine Triphosphate; Calcium-Binding Proteins; Carrier Proteins; Cell Membrane; Galactose; Kinetics; Liposomes; Membrane Potentials; Monosaccharide Transport Proteins; NAD; Periplasmic Binding Proteins; Proteolipids; Salmonella typhimurium; Thioctic Acid

1987
Thioredoxin fragment 31-36 is reduced by dihydrolipoamide and reduces oxidized protein.
    Biochemical and biophysical research communications, 1988, Jan-15, Volume: 150, Issue:1

    Topics: Bacterial Proteins; Crystallins; Dihydrolipoamide Dehydrogenase; Disulfides; Escherichia coli; Glyceraldehyde-3-Phosphate Dehydrogenases; Insulin; Kinetics; NAD; Oxidation-Reduction; Peptide Fragments; Proteins; Spectrophotometry; Thioctic Acid; Thioredoxin-Disulfide Reductase; Thioredoxins

1988
Resolution and characterization of the glycine-cleavage reaction in pea leaf mitochondria. Properties of the forward reaction catalysed by glycine decarboxylase and serine hydroxymethyltransferase.
    The Biochemical journal, 1988, Oct-01, Volume: 255, Issue:1

    Topics: Amino Acid Oxidoreductases; Aminomethyltransferase; Carrier Proteins; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Glycine; Glycine Decarboxylase Complex H-Protein; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Hydroxymethyl and Formyl Transferases; Mitochondria; Multienzyme Complexes; NAD; Oxidation-Reduction; Plant Proteins; Plants; Pyruvate Dehydrogenase Complex; Tetrahydrofolates; Thioctic Acid; Transferases

1988
Cytosolic cofactors and dihydrolipoamide stimulate hepatic microsomal 5'-deiodination.
    Endocrinology, 1985, Volume: 117, Issue:3

    Topics: Animals; Cytosol; Dihydrolipoamide Dehydrogenase; Dithiothreitol; Iodide Peroxidase; Male; Microsomes, Liver; NAD; Peroxidases; Rats; Rats, Inbred Strains; Thioctic Acid

1985
Effect of coenzyme-A, NAD, alpha lipoic-acid and cocarboxylase on survival of rats with galactosamine-induced severe hepatitis.
    Experientia, 1985, Aug-15, Volume: 41, Issue:8

    Topics: Animals; Coenzyme A; Disease Models, Animal; Female; Galactosamine; Hepatitis; Liver Function Tests; NAD; Rats; Rats, Inbred Strains; Thiamine Pyrophosphate; Thioctic Acid

1985
[Histochemical studies in malpositions of the testis following treatment with human chorionic gonadotropin (HCG) in animal experiment and clinical patient material].
    Annales Universitatis Saraviensis. Medizin, 1972, Volume: 19, Issue:2

    Topics: Adolescent; Animals; Child; Child, Preschool; Chorionic Gonadotropin; Cryptorchidism; Dihydrolipoamide Dehydrogenase; Glucosephosphate Dehydrogenase; Histocytochemistry; Humans; Infant; Infant, Newborn; L-Lactate Dehydrogenase; Male; NAD; Oxidoreductases; Rats; Testosterone; Thioctic Acid

1972
Studies on lipoyl dehydrogenase from Escherichia coli.
    The Journal of biological chemistry, 1965, Volume: 240, Issue:12

    Topics: Arsenicals; Catalysis; Escherichia coli; In Vitro Techniques; Molecular Biology; Mutation; NAD; Oxidoreductases; Thioctic Acid

1965
[Treatment of endogenic hepatic coma by coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase].
    Revue medico-chirurgicale des maladies du foie, 1966, Volume: 41, Issue:1

    Topics: Coenzyme A; Hepatic Encephalopathy; Humans; NAD; Thiamine Pyrophosphate; Thioctic Acid

1966
Mammalian alpha-keto acid dehydrogenase complexes. I. Isolation, purification, and properties of pyruvate dehydrogenase complex of pig heart muscle.
    The Journal of biological chemistry, 1966, Oct-25, Volume: 241, Issue:20

    Topics: Acyltransferases; Animals; Coenzyme A; Dihydrolipoamide Dehydrogenase; Electrophoresis; Flavin-Adenine Dinucleotide; In Vitro Techniques; Molecular Weight; Muscles; NAD; Oxidoreductases; Pyruvates; Swine; Thioctic Acid; Ultracentrifugation

1966
Lipoamide dehydrogenase from human liver.
    The Journal of biological chemistry, 1967, Jan-10, Volume: 242, Issue:1

    Topics: Dihydrolipoamide Dehydrogenase; Electrophoresis; Humans; In Vitro Techniques; Liver; Molecular Weight; NAD; Thioctic Acid; Ultracentrifugation

1967
Flavin-pyridinium biscoenzyme analogs. Synthesis and reactivity.
    Biochemistry, 1967, Volume: 6, Issue:10

    Topics: Catalysis; Coenzymes; Enzymes; Flavins; Kinetics; Models, Biological; NAD; Niacinamide; Oxidation-Reduction; Pyridinium Compounds; Spectrophotometry; Thioctic Acid

1967
[Coenzyme treatment of severe jaundice due to hepatitis (Thölen's method)].
    Rein et foie, maladies de la nutrition; actualites, 1967, Volume: 10

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Coenzyme A; Coenzymes; Female; Hepatic Encephalopathy; Hepatitis; Humans; Injections, Intravenous; Jaundice; Middle Aged; NAD; Thiamine Pyrophosphate; Thioctic Acid

1967
Effects of a treatment with coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase on endogenous hepatic coma.
    Helvetica medica acta, 1967, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Ammonia; Bilirubin; Biopsy; Blood Coagulation Factors; Blood Coagulation Tests; Blood Protein Electrophoresis; Coenzyme A; Electroencephalography; Enzymes; Female; Hepatic Encephalopathy; Humans; Iron; Lactates; Liver; Male; Middle Aged; NAD; Necrosis; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1967
[What is the current status of therapeutic possibilities in severe juandice?].
    La Presse medicale, 1968, Mar-23, Volume: 76, Issue:14

    Topics: Adolescent; Adult; Child; Coenzyme A; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Hyperbaric Oxygenation; Jaundice; Kidneys, Artificial; Liver; Liver Diseases; Middle Aged; NAD; Perfusion; Peritoneal Dialysis; Prednisolone; Thiamine Pyrophosphate; Thioctic Acid

1968
The mechanism of disulphide reduction by mitochondria.
    The Biochemical journal, 1968, Volume: 108, Issue:4

    Topics: Animals; Antimycin A; Arsenic; Cystamine; Depression, Chemical; Dihydrolipoamide Dehydrogenase; Keto Acids; Mitochondria, Liver; NAD; Osmosis; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Rats; Rotenone; Stimulation, Chemical; Sulfides; Sulfur Isotopes; Thioctic Acid; Ultrasonics

1968
Studies on lipoic acid uptake by bacteria. 3. Intracellular distribution of enzymes.
    Canadian journal of microbiology, 1969, Volume: 15, Issue:2

    Topics: Bacteriolysis; Biological Transport, Active; Cell Membrane; Detergents; Enterococcus faecalis; Escherichia coli; Glucosephosphate Dehydrogenase; Malate Dehydrogenase; NAD; Oxidoreductases; Protoplasts; Pyruvates; Thioctic Acid

1969
Mammalian alpha-keto acid dehydrogenase complexes. V. Resolution and reconstitution studies of the pig heart pyruvate dehydrogenase complex.
    The Journal of biological chemistry, 1969, Jul-10, Volume: 244, Issue:13

    Topics: Acyltransferases; Animals; Chemical Phenomena; Chemistry; Coenzyme A; Dihydrolipoamide Dehydrogenase; Flavins; Microscopy, Electron; Molecular Weight; Muscles; Myocardium; NAD; Oxidoreductases; Pyruvates; Swine; Thioctic Acid; Ultracentrifugation

1969
Reduced forms of the flavoprotein from egg-yolk.
    Bulletin de la Societe de chimie biologique, 1969, Oct-23, Volume: 51, Issue:6

    Topics: Animals; Chickens; Chromatography, Gel; Egg Yolk; Electrodes; Female; Flavins; Fluorometry; Mercury; NAD; Oxidation-Reduction; Proteins; Quinones; Riboflavin; Spectrophotometry; Sulfur; Thioctic Acid

1969
[Clinical trial of a new coenzyme complex in patients with liver disease].
    La Clinica terapeutica, 1970, Feb-15, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Aged; Coenzyme A; Female; Gallbladder Diseases; Humans; Liver Diseases; Male; Middle Aged; NAD; Thiamine Pyrophosphate; Thioctic Acid

1970
Purification and properties of the alpha-ketoglutarate dehydrogenase complex of cauliflower mitochondria.
    The Journal of biological chemistry, 1970, Nov-10, Volume: 245, Issue:21

    Topics: Acyltransferases; Animals; Calcium; Chemical Phenomena; Chemistry; Coenzyme A; Dihydrolipoamide Dehydrogenase; Edetic Acid; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Magnesium; Mitochondria; Myocardium; NAD; Oxidoreductases; Plants; Protein Binding; Succinates; Swine; Thiamine Pyrophosphate; Thioctic Acid

1970
[Importance of biological membranes in metabolism and effects of some functionally bound vitamins].
    Ukrains'kyi biokhimichnyi zhurnal, 1970, Volume: 42, Issue:3

    Topics: Animals; Cell Membrane Permeability; Coenzyme A; Coenzymes; Flavin-Adenine Dinucleotide; Mitochondria, Liver; NAD; Oxidoreductases; Rats; Thiamine Pyrophosphate; Thioctic Acid; Vitamins

1970
Circular dichroism of reduced and oxidized mammalian lipoamide dehydrogenase.
    The Journal of biological chemistry, 1971, Sep-10, Volume: 246, Issue:17

    Topics: Animals; Carbonates; Cattle; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Circular Dichroism; Cryptococcus; Dihydrolipoamide Dehydrogenase; Electrophoresis; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Guanidines; Hydrochloric Acid; Hydrogen-Ion Concentration; Myocardium; NAD; Oxidation-Reduction; Phosgene; Protein Binding; Protein Conformation; Riboflavin; Spectrophotometry; Swine; Temperature; Thioctic Acid; Ultraviolet Rays

1971
[Current views on the therapy of hepatic coma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Apr-15, Volume: 25, Issue:8

    Topics: Acute Kidney Injury; Adolescent; Amino Acids; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Acid; Coenzyme A; Diet Therapy; Exchange Transfusion, Whole Blood; Glutamates; Hepatic Encephalopathy; Humans; Malates; Male; NAD; Ornithine; Prednisone; Prognosis; Renal Dialysis; Thiamine Pyrophosphate; Thioctic Acid; Vasopressins

1970
Glutathione. VII. Differentiation among substrates by the thiol-oxidizing agent, diamide.
    Biochimica et biophysica acta, 1972, Mar-30, Volume: 264, Issue:1

    Topics: Azo Compounds; Cells; Chemical Phenomena; Chemistry; Coenzyme A; Disulfides; Erythrocytes; Formamides; Glutathione; Humans; Kinetics; Mathematics; NAD; Oxidation-Reduction; Spectrophotometry; Sulfhydryl Compounds; Thioctic Acid; Ultraviolet Rays

1972
Mammalian -keto acid dehydrogenase complexes. VII. Resolution and reconstitution of the pig heart 2-oxoglutarate dehydrogenase complex.
    The Journal of biological chemistry, 1972, Jun-25, Volume: 247, Issue:12

    Topics: Acyltransferases; Animals; Chemical Precipitation; Chromatography; Chromatography, Gel; Coenzymes; Dihydrolipoamide Dehydrogenase; Dithiothreitol; Guanidines; Ketoglutaric Acids; Macromolecular Substances; Microscopy, Electron; Mitochondria, Muscle; Myocardium; NAD; Oxidoreductases; Protamines; Protein Conformation; Solubility; Succinates; Surface-Active Agents; Swine; Thioctic Acid; Ultracentrifugation

1972
Classical maple syrup urine disease: cofactor resistance.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:10

    Topics: Amino Acids; Carbon Isotopes; Cells, Cultured; Coenzyme A; Coenzymes; Female; Fibroblasts; Flavin-Adenine Dinucleotide; Genetics, Medical; Humans; Infant, Newborn; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; NAD; Pyridoxal Phosphate; Pyruvates; Skin; Thiamine Pyrophosphate; Thioctic Acid; Valine

1972
The subunit structure of the pyruvate-dehydrogenase complex from Escherichia coli K-12. The core complex.
    European journal of biochemistry, 1972, Volume: 30, Issue:2

    Topics: Acetyltransferases; Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ketone Oxidoreductases; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; NAD; Protein Denaturation; Pyruvate Dehydrogenase Complex; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Thioctic Acid; Ultracentrifugation

1972
Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification, interconversion and some properties.
    The Biochemical journal, 1973, Volume: 131, Issue:2

    Topics: Animals; Cattle; Chymotrypsin; Dithiothreitol; Electrophoresis, Disc; Kinetics; Milk; Multienzyme Complexes; NAD; Papain; Spectrophotometry, Ultraviolet; Subtilisins; Thioctic Acid; Time Factors; Xanthine Oxidase

1973
Alpha-keto acid dehydrogenase complexes. XX. A kinetic study of the pyruvate dehydrogenase complex from bovine kidney.
    The Journal of biological chemistry, 1973, Dec-25, Volume: 248, Issue:24

    Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Cattle; Coenzyme A; Flavoproteins; Kidney; Kinetics; Macromolecular Substances; Mathematics; Mitochondria; NAD; Protein Binding; Pyruvate Dehydrogenase Complex; Pyruvates; Spectrophotometry, Ultraviolet; Thioctic Acid

1973
Permeation of nucleotidic coenzymes into liver cells.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 10, Issue:2

    Topics: Animals; Cell Membrane Permeability; Coenzyme A; Coenzymes; Female; In Vitro Techniques; Liver; NAD; Nucleotides; Oxygen Consumption; Rats; Thioctic Acid

1974
A comparative study of the reversibility of the reaction catalysed by bacterial lipoamide dehydrogenase.
    Biochimica et biophysica acta, 1968, Apr-24, Volume: 159, Issue:1

    Topics: Amides; Aniline Compounds; Bacteria; Cell-Free System; Dihydrolipoamide Dehydrogenase; Edetic Acid; Escherichia coli; Fermentation; Ferricyanides; Hydrogen-Ion Concentration; Indophenol; L-Lactate Dehydrogenase; NAD; NADP; Thioctic Acid

1968
[Coenzymes (vitamins)].
    L' Alimentation et la vie, 1970, Volume: 58, Issue:1

    Topics: Ascorbic Acid; Biotin; Chemical Phenomena; Chemistry; Coenzyme A; Coenzymes; Cytochromes; Flavin-Adenine Dinucleotide; Folic Acid; Glutathione; NAD; NADP; Nucleosides; Pyridoxine; Thiamine; Thioctic Acid; Ubiquinone; Vitamins

1970
The purification and properties of the respiratory-chain reduced nicotinamide--adenine dinucleotide dehydrogenase of Torulopsis utilis.
    The Biochemical journal, 1971, Volume: 124, Issue:5

    Topics: Cytochromes; Electron Spin Resonance Spectroscopy; Ferricyanides; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Imines; Iron; Kinetics; Mitochondria; Mitosporic Fungi; NAD; NADP; Oxidoreductases; Phenotype; Quinones; Spectrophotometry; Sulfides; Thioctic Acid; Ubiquinone; Vitamin K

1971
Intracellular localization and co-factor requirement of amphetamine-tetrazolium reductase of guinea-pig brain.
    Biochemical pharmacology, 1972, Jul-15, Volume: 21, Issue:14

    Topics: Amphetamine; Animals; Brain; Coenzymes; Cyanides; Dextroamphetamine; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Guinea Pigs; Hydrogen-Ion Concentration; Male; Mitochondria; NAD; NADP; Oxidoreductases; Subcellular Fractions; Tetrazolium Salts; Thioctic Acid

1972
Stimulation of iodothyronine outer ring monodeiodinase by dihydrolipoamide.
    Endocrinology, 1983, Volume: 112, Issue:4

    Topics: Animals; Dicumarol; Dithiothreitol; Enzyme Activation; Iodide Peroxidase; Kidney; Kinetics; Microsomes; NAD; Peroxidases; Propylthiouracil; Rats; Temperature; Thioctic Acid

1983
The reduction of disulphides by rat liver mitochondria.
    Biochimica et biophysica acta, 1984, Feb-14, Volume: 797, Issue:2

    Topics: Animals; Disulfides; Glutathione; Kinetics; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; Thioctic Acid

1984
Kinetic studies of multifunctional reactions catalysed by lipoamide dehydrogenase.
    The International journal of biochemistry, 1980, Volume: 11, Issue:5

    Topics: 2,6-Dichloroindophenol; Animals; Dihydrolipoamide Dehydrogenase; Ferricyanides; Kinetics; Mathematics; NAD; Swine; Thioctic Acid

1980
The role of lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli.
    The Biochemical journal, 1981, Dec-01, Volume: 199, Issue:3

    Topics: Acetyl Coenzyme A; Acetylation; Escherichia coli; Ethylmaleimide; NAD; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1981
Optimal conditions for the assay of lipoamide dehydrogenase in homogenized human platelets.
    Clinica chimica acta; international journal of clinical chemistry, 1982, May-06, Volume: 121, Issue:1

    Topics: Blood Platelets; Dihydrolipoamide Dehydrogenase; Humans; Hydrogen-Ion Concentration; Kinetics; Methods; NAD; Thioctic Acid

1982
Dihydrolipoamide dehydrogenase: activity assays.
    Methods in enzymology, 1995, Volume: 252

    Topics: Animals; Dihydrolipoamide Dehydrogenase; Eukaryotic Cells; Humans; NAD; Oxidation-Reduction; Prokaryotic Cells; Rats; Species Specificity; Swine; Thioctic Acid

1995
Using lipoate enantiomers and thioredoxin to study the mechanism of the 2-oxoacid-dependent dihydrolipoate production by the 2-oxoacid dehydrogenase complexes.
    FEBS letters, 1995, Sep-04, Volume: 371, Issue:2

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Biphenyl Compounds; Chemical Precipitation; Escherichia coli; Flavin-Adenine Dinucleotide; Insulin; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Multienzyme Complexes; NAD; Onium Compounds; Pyruvate Dehydrogenase Complex; Stereoisomerism; Thioctic Acid; Thioredoxins

1995
Modulation of the oxidation-reduction potential of the flavin in lipoamide dehydrogenase from Escherichia coli by alteration of a nearby charged residue, K53R.
    Biochemistry, 1994, May-24, Volume: 33, Issue:20

    Topics: Circular Dichroism; Dihydrolipoamide Dehydrogenase; Electrochemistry; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Lysine; NAD; Oxidation-Reduction; Photochemistry; Spectrometry, Fluorescence; Spectrophotometry; Thioctic Acid

1994
The role of lipoic acid in product formation by Enterococcus faecalis NCTC 775 and reconstitution in vivo and in vitro of the pyruvate dehydrogenase complex.
    Journal of general microbiology, 1993, Volume: 139 Pt 6

    Topics: Acetoin; Aerobiosis; Anaerobiosis; Enterococcus faecalis; Fermentation; Glucose; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; NAD; Pyruvate Dehydrogenase Complex; Thioctic Acid

1993
Three-dimensional structure of lipoamide dehydrogenase from Pseudomonas fluorescens at 2.8 A resolution. Analysis of redox and thermostability properties.
    Journal of molecular biology, 1993, Apr-20, Volume: 230, Issue:4

    Topics: Amino Acid Sequence; Azotobacter vinelandii; Binding Sites; Catalysis; Crystallization; Dihydrolipoamide Dehydrogenase; Electronic Data Processing; Flavin-Adenine Dinucleotide; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutation; NAD; Oxidation-Reduction; Protein Conformation; Protein Denaturation; Pseudomonas fluorescens; Recombinant Proteins; Sequence Homology, Amino Acid; Thioctic Acid; X-Ray Diffraction

1993
Reduction of lipoic acid by lipoamide dehydrogenase.
    Biochemical pharmacology, 1996, Feb-09, Volume: 51, Issue:3

    Topics: Animals; Antioxidants; Dihydrolipoamide Dehydrogenase; Mitochondria, Heart; NAD; Oxidation-Reduction; Stereoisomerism; Substrate Specificity; Swine; Thioctic Acid

1996
Stoichiometry, organisation and catalytic function of protein X of the pyruvate dehydrogenase complex from bovine heart.
    European journal of biochemistry, 1996, Feb-15, Volume: 236, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Cattle; Collagenases; Cross-Linking Reagents; Myocardium; NAD; Peptides; Protein Conformation; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1996
Amplified determination of lipoyl groups by lipoamide dehydrogenase in the presence of oxidized glutathione.
    Biochemistry and molecular biology international, 1996, Volume: 38, Issue:6

    Topics: Dihydrolipoamide Dehydrogenase; Disulfides; Glutathione; Glutathione Disulfide; Kinetics; Lysine; NAD; Oxidation-Reduction; Substrate Specificity; Thioctic Acid

1996
Stimulation of Ca2+ release from rat liver mitochondria by the dithiol reagent alpha-lipoic acid.
    Biochemical pharmacology, 1996, Dec-24, Volume: 52, Issue:12

    Topics: Animals; Biological Transport; Calcium; Glutathione; Membrane Potentials; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Rats; Sulfhydryl Compounds; Thioctic Acid

1996
Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of alpha-lipoic acid.
    Free radical biology & medicine, 1997, Volume: 22, Issue:3

    Topics: Animals; Brain; Cytosol; Dihydrolipoamide Dehydrogenase; Glutathione Reductase; Kidney; Liver; Male; Mitochondria; Myocardium; NAD; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substrate Specificity; Thioctic Acid

1997
Modulation of cellular reducing equivalent homeostasis by alpha-lipoic acid. Mechanisms and implications for diabetes and ischemic injury.
    Biochemical pharmacology, 1997, Feb-07, Volume: 53, Issue:3

    Topics: Cells, Cultured; Glucose; Homeostasis; Humans; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Thioctic Acid

1997
Assay of protein-bound lipoic acid in tissues by a new enzymatic method.
    Analytical biochemistry, 1998, May-01, Volume: 258, Issue:2

    Topics: Animals; Cattle; Dihydrolipoamide Dehydrogenase; Glutathione Disulfide; Lysine; NAD; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Rats; Thioctic Acid

1998
Diabetes-induced changes in lens antioxidant status, glucose utilization and energy metabolism: effect of DL-alpha-lipoic acid.
    Diabetologia, 1998, Volume: 41, Issue:12

    Topics: Adenine Nucleotides; Animals; Antioxidants; Diabetes Mellitus, Experimental; Energy Metabolism; Fructose; Glucose; Glutathione; Glycolysis; Lens, Crystalline; Male; NAD; NADP; Oxidative Stress; Rats; Rats, Wistar; Sorbitol; Thioctic Acid

1998
Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart.
    Free radical biology & medicine, 1999, Volume: 27, Issue:9-10

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antioxidants; DNA Damage; Enzyme Activation; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; NAD; Perfusion; Poly(ADP-ribose) Polymerases; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Thioctic Acid

1999
[Diabetic neuropathy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2000, Volume: 100, Issue:10

    Topics: Acupuncture Therapy; Adjuvants, Immunologic; Antioxidants; Combined Modality Therapy; Diabetic Neuropathies; Humans; Lipid Peroxidation; NAD; NADP; Nitric Oxide Synthase; Paresthesia; Severity of Illness Index; Thiamine; Thioctic Acid; Treatment Outcome

2000
Thiols can either enhance or suppress DNA damage induction by catecholestrogens.
    Free radical biology & medicine, 2001, Jan-01, Volume: 30, Issue:1

    Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; DNA Damage; Drug Resistance, Neoplasm; Estradiol; Estrogens, Catechol; Glutathione; Hydrogen Peroxide; Kinetics; Methotrexate; NAD; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thioctic Acid

2001
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
    Pharmacology, 2001, Volume: 62, Issue:3

    Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid

2001
Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.
    Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557

    Topics: Acyltransferases; Amino Acid Sequence; Antioxidants; Binding Sites; Catalysis; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Dihydrolipoamide Dehydrogenase; Hydrogen Bonding; Hydrogen Peroxide; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Oxidoreductases; Peroxidases; Peroxiredoxins; Peroxynitrous Acid; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Thioctic Acid; Thioredoxins

2002
Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.
    Free radical biology & medicine, 2002, Jul-01, Volume: 33, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Dehydroascorbic Acid; Endothelium, Vascular; Ferricyanides; Fluoresceins; Glucose; Glutathione; Humans; NAD; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidation-Reduction; Reactive Oxygen Species; Thioctic Acid; Umbilical Veins

2002
Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species.
    European journal of biochemistry, 2002, Volume: 269, Issue:20

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Catalysis; Coenzyme A; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Enzyme Activation; Flavin-Adenine Dinucleotide; Free Radicals; Ketone Oxidoreductases; Multienzyme Complexes; NAD; Nitrogen Oxides; Spin Labels; Superoxides; Thioctic Acid; Thioredoxins

2002
The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis.
    Biochemistry, 2002, Dec-10, Volume: 41, Issue:49

    Topics: Bacterial Proteins; Catalysis; Dihydrolipoamide Dehydrogenase; Electron Transport; Flavin-Adenine Dinucleotide; Models, Chemical; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Spectrophotometry; Spectrophotometry, Ultraviolet; Thermodynamics; Thioctic Acid

2002
Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level.
    Biochemistry, 2003, Feb-25, Volume: 42, Issue:7

    Topics: Bacterial Proteins; Benzoquinones; Catalysis; Dihydrolipoamide Dehydrogenase; Flavin-Adenine Dinucleotide; Kinetics; Mycobacterium tuberculosis; NAD; Oxidants; Oxidation-Reduction; Oxygen; Pentanoic Acids; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Thioctic Acid

2003
[Efficacy of a mixture of cocarboxylase, DPN, coenzyme A and lipoic acid on hyperpyruvicemia].
    Minerva chirurgica, 1961, Apr-30, Volume: 16

    Topics: Coenzyme A; Coenzymes; Humans; NAD; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1961
[Therapy of hepatic coma with coenzyme A, alpha-lipoic acid and diphosphopyridine nucleotide].
    Deutsche medizinische Wochenschrift (1946), 1962, Nov-30, Volume: 87

    Topics: Coenzyme A; Hepatic Encephalopathy; Humans; NAD; Thioctic Acid

1962
PYRIDINE NUCLEOTIDE-STIMULATED PRODUCTION OF 3'-PHOSPHOADENOSINE 5'-PHOSPHATE BY BEEF-CORNEA-EPITHELIAL EXTRACT.
    Biochimica et biophysica acta, 1963, Sep-03, Volume: 77

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cattle; Cornea; Electrophoresis; Epithelium; Metabolism; NAD; NADP; Nitrophenols; Nucleotides; Pyridines; Research; Sulfur Isotopes; Thioctic Acid; Tissue Extracts

1963
PURIFICATION AND PROPERTIES OF GLUTATHIONE REDUCTASE OF HUMAN ERYTHROCYTES.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Chromatography; Erythrocytes; Glutathione; Glutathione Reductase; NAD; NADP; Oxidoreductases; Research; Thioctic Acid

1963
[ON THE PATHOGENESIS AND THERAPY OF THE ENDOGENOUS HEPATIC COMA].
    Schweizerische medizinische Wochenschrift, 1963, Dec-28, Volume: 93

    Topics: Blood Chemical Analysis; Coenzyme A; Glycols; Hepatic Encephalopathy; Humans; Ketones; NAD; Pyruvates; Thioctic Acid

1963
DIVERGENT RESPONSE TO INHIBITION BY PHENYLALANINE AND TRYPTOPHAN HYDROXYLATING SYSTEMS IN VITRO.
    Biochimica et biophysica acta, 1964, Jun-01, Volume: 85

    Topics: Amino Acids; Ascorbic Acid; Benzoates; Borates; Dimercaprol; Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Liver; Mixed Function Oxygenases; NAD; Pharmacology; Phenylalanine; Pterins; Rats; Research; Thioctic Acid; Tryptophan

1964
LACTATE-DEGRADING SYSTEM IN BUTYRIBACTERIUM RETTGERI SUBJECT TO GLUCOSE REPRESSION.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Culture Media; Eubacterium; Fructose; Glucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Metabolism; NAD; Oxidation-Reduction; Oxidoreductases; Pyruvates; Pyruvic Acid; Research; Thioctic Acid; United States

1964
ELECTRON TRANSPORT IN PEPTOSTREPTOCOCCUS ELSDENII.
    Biochimica et biophysica acta, 1964, Dec-23, Volume: 92

    Topics: Arsenicals; Butyrates; Coenzyme A; Edetic Acid; Electron Transport; Ferredoxins; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Indophenol; Iodoacetates; L-Lactate Dehydrogenase; Metabolism; NAD; Oxidoreductases; Peptostreptococcus; Pharmacology; Propionates; Protamines; Pyruvates; Research; Spectrophotometry; Sulfhydryl Compounds; Thioctic Acid

1964
Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease.
    Neurotoxicity research, 2003, Volume: 5, Issue:7

    Topics: Acrolein; Alzheimer Disease; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Ketoglutarate Dehydrogenase Complex; Mitochondria; NAD; Pyruvate Dehydrogenase Complex; Thioctic Acid

2003
Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
    Biochemistry, 2004, Oct-26, Volume: 43, Issue:42

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Buffers; Dihydrolipoyllysine-Residue Acetyltransferase; Dithionitrobenzoic Acid; Enzyme Activation; Isoenzymes; Kinetics; NAD; Oxidation-Reduction; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Subunits; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Sequence Deletion; Substrate Specificity; Thioctic Acid

2004
Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations.
    Journal of molecular biology, 2005, Jul-15, Volume: 350, Issue:3

    Topics: Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Databases, Protein; Dihydrolipoamide Dehydrogenase; Dimerization; Disulfides; Glycine; Humans; Maple Syrup Urine Disease; Models, Molecular; Mutation; NAD; Niacinamide; Oxygen; Potyvirus; Protein Binding; Pseudomonas putida; Saccharomyces cerevisiae; Thioctic Acid

2005
Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE.
    Electrophoresis, 2007, Volume: 28, Issue:7

    Topics: Animals; Chromatography, Liquid; Dihydrolipoamide Dehydrogenase; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ethylmaleimide; Mitochondrial Proteins; NAD; Nitroblue Tetrazolium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Staining and Labeling; Tandem Mass Spectrometry; Thioctic Acid

2007
Uptake and reduction of alpha-lipoic acid by human erythrocytes.
    Clinical biochemistry, 2007, Volume: 40, Issue:15

    Topics: Ascorbic Acid; Dinitrobenzenes; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Humans; In Vitro Techniques; NAD; Oxidation-Reduction; Thioctic Acid

2007
Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate.
    The Journal of biological chemistry, 2007, Oct-05, Volume: 282, Issue:40

    Topics: Dihydrolipoamide Dehydrogenase; Flavins; Kinetics; Models, Chemical; NAD; Protein Binding; Protein Structure, Tertiary; Pyruvate Dehydrogenase Complex; Recombinant Proteins; Sequence Analysis, DNA; Streptococcus pneumoniae; Substrate Specificity; Sulfhydryl Compounds; Thioctic Acid

2007
Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase .
    Biochemistry, 2010, Mar-02, Volume: 49, Issue:8

    Topics: Animals; Antitubercular Agents; Binding Sites; Cell Survival; Cells, Cultured; Crystallography, X-Ray; Dihydrolipoamide Dehydrogenase; Enzyme Inhibitors; Macrophages; Mice; Models, Biological; Molecular Structure; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; NAD; Structure-Activity Relationship; Thioctic Acid

2010
Mitochondrial dysfunction and chronic disease: treatment with natural supplements.
    Alternative therapies in health and medicine, 2014,Winter, Volume: 20 Suppl 1

    Topics: Carnitine; Dietary Supplements; Fatigue Syndrome, Chronic; Humans; Mitochondrial Diseases; NAD; Thioctic Acid; Ubiquinone

2014
Conformational Change Near the Redox Center of Dihydrolipoamide Dehydrogenase Induced by NAD(+) to Regulate the Enzyme Activity.
    Journal of fluorescence, 2015, Volume: 25, Issue:3

    Topics: Catalysis; Catalytic Domain; Dihydrolipoamide Dehydrogenase; Electron Transport; Flavin-Adenine Dinucleotide; NAD; Oxidation-Reduction; Protein Conformation; Thioctic Acid

2015
Detoxification of hexavalent chromium by Leucobacter sp. uses a reductase with specificity for dihydrolipoamide.
    Journal of basic microbiology, 2016, Volume: 56, Issue:2

    Topics: Actinobacteria; Biotransformation; Chromatography, Liquid; Chromium; Coenzymes; Dihydrolipoamide Dehydrogenase; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrogen-Ion Concentration; Mass Spectrometry; Molecular Weight; NAD; NADP; Oxidoreductases; Spectrophotometry; Temperature; Thioctic Acid

2016
Functional Reconstitution of a Pyruvate Dehydrogenase in the Cytosol of Saccharomyces cerevisiae through Lipoylation Machinery Engineering.
    ACS synthetic biology, 2016, 07-15, Volume: 5, Issue:7

    Topics: Acetyl Coenzyme A; Caprylates; Cytosol; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Genetic Engineering; Lipoylation; Metabolic Networks and Pathways; Mutation; NAD; Pyruvate Dehydrogenase Complex; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thioctic Acid

2016
Mutational studies on Leishmania donovani dihydrolipoamide dehydrogenase (LdBPK291950.1) indicates that the enzyme may not be classical class-I pyridine nucleotide-disulfide oxidoreductase.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: Amino Acid Sequence; Amino Acid Substitution; Catalysis; Catalytic Domain; Dihydrolipoamide Dehydrogenase; Disulfides; Leishmania donovani; Mutation; NAD; Nucleotides; Oxidoreductases; Pyridines; Sequence Alignment; Thioctic Acid

2020