thioctic acid and methotrexate

thioctic acid has been researched along with methotrexate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's12 (80.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Courteau, J; Kocsis-Bédard, S; Niyonsenga, T; Paquette, B; Thibodeau, PA1
Dadhania, VP; Jena, GB; Ramarao, P; Tripathi, DN; Vikram, A1
Banerjee, BD; Parvez, S; Pasha, ST; Raisuddin, S; Tabassum, H1
Abolhassani, M; Baronzio, G; Behzadi, M; Campion, F; Fiorentini, G; Guais, A; Mainini, C; Montagnani, F; Sanders, E; Schwartz, L1
Abad, GD; Ghabili, K; Hajipour, B; Hemmati, MR; Khodadadi, A; Somi, MH; Vatankhah, AM1
Armagan, HH; Armagan, I; Bayram, D; Candan, IA; Celik, E; Uğuz, AC; Yigit, A1
Aslaner, A; Baştürk, A; Çakır, T; Durgut, H; Gül, M; Gül, S; Öğünç, AV; Oruç, MT; Polat, C; Sabuncuoglu, MZ; Şehirli, AÖ1
Aslaner, A; Aykaç, A; Bahar, L; Baştürk, A; Çakır, T; Durgut, H; Gül, M; Polat, C; Sabuncuoglu, MZ; Şehirli, AÖ1
Ahmed, AA; El-Sayed, NM; Selim, MA1
Arpag, H; Atilla, N; Aydemir, Y; Cakir, T; Gül, M; Polat, C; Sayan, M; Yiğitcan, B; Þehirli, Ö1
Dolapçıoğlu, K; Özcan, O; Özgür, T; Pinar, N; Soylu Karapinar, O1
Çakırca, G; Kaplan, M; Özgür, T; Pınar, N1
Fayez, AM; Moustafa, D; Zakaria, S1
Chen, L; Fan, X; Fei, Z; Han, Q; Luo, Q; Wang, Y; Zhang, H1
Abd Hasan, RR; Aggad, SS; Al-Gareeb, AIA; Al-Kuraishy, HM; Aljohani, ASM; Batiha, GE; El-Ashmawy, IM; Elekhnawy, E; Mostafa, SA; Negm, WA1

Other Studies

15 other study(ies) available for thioctic acid and methotrexate

ArticleYear
Thiols can either enhance or suppress DNA damage induction by catecholestrogens.
    Free radical biology & medicine, 2001, Jan-01, Volume: 30, Issue:1

    Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; DNA Damage; Drug Resistance, Neoplasm; Estradiol; Estrogens, Catechol; Glutathione; Hydrogen Peroxide; Kinetics; Methotrexate; NAD; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thioctic Acid

2001
Intervention of alpha-lipoic acid ameliorates methotrexate-induced oxidative stress and genotoxicity: A study in rat intestine.
    Chemico-biological interactions, 2010, Jan-05, Volume: 183, Issue:1

    Topics: Alkaline Phosphatase; Animals; Antimetabolites, Antineoplastic; Comet Assay; DNA Damage; Glutathione; In Situ Nick-End Labeling; Intestines; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tumor Suppressor Protein p53

2010
Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondria.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:7

    Topics: Animals; Body Weight; DNA; Folic Acid Antagonists; Free Radicals; Glutathione; Glutathione Peroxidase; In Vitro Techniques; Lipid Metabolism; Methotrexate; Mice; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances; Thioctic Acid

2010
Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cisplatin; Citrates; Deoxycytidine; Energy Metabolism; Female; Gemcitabine; Humans; Methotrexate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pancreatic Neoplasms; Thioctic Acid; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Urinary Bladder Neoplasms

2012
Protective role of lipoic acid on methotrexate induced intestinal damage in rabbit model.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2011, Volume: 30, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Glutathione Peroxidase; Intestinal Mucosa; Intestine, Small; Male; Malondialdehyde; Methotrexate; Models, Animal; Oxidative Stress; Protective Agents; Rabbits; Random Allocation; Superoxide Dismutase; Thioctic Acid

2011
Effects of pentoxifylline and alpha lipoic acid on methotrexate-induced damage in liver and kidney of rats.
    Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:3

    Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Kidney Diseases; Male; Methotrexate; Pentoxifylline; Rats; Rats, Sprague-Dawley; Thioctic Acid

2015
Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats?
    Acta cirurgica brasileira, 2015, Volume: 30, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Methotrexate; Necrosis; Peroxidase; Random Allocation; Rats, Wistar; Reproducibility of Results; Thioctic Acid; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Female; Glutathione; Interleukin-1beta; Kidney; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Thioctic Acid; Tumor Necrosis Factor-alpha

2015
α-Lipoic acid ameliorates oral mucositis and oxidative stress induced by methotrexate in rats. Histological and immunohistochemical study.
    Life sciences, 2017, Feb-15, Volume: 171

    Topics: Animals; Biomarkers; Diarrhea; DNA; Immunohistochemistry; Male; Methotrexate; Mouth Mucosa; Oxidative Stress; Rats; Rats, Wistar; Stomatitis; Thioctic Acid

2017
Protective Effects of Alpha-Lipoic Acid on Methotrexate-Induced Oxidative Lung Injury in Rats.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2018, Volume: 31, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Glutathione; Humans; Interleukin-1beta; Lung; Lung Injury; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thioctic Acid; Tumor Necrosis Factor-alpha

2018
Protective effect of alpha-lipoic acid in methotrexate-induced ovarian oxidative injury and decreased ovarian reserve in rats.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017, Volume: 33, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Mullerian Hormone; Antimetabolites, Antineoplastic; Antioxidants; Biomarkers; Dietary Supplements; Female; Folic Acid Antagonists; Infertility, Female; Lipid Peroxidation; Methotrexate; Nucleic Acid Synthesis Inhibitors; Ovarian Reserve; Ovary; Oxidative Stress; Random Allocation; Rats, Wistar; Thioctic Acid; Tumor Necrosis Factor-alpha

2017
The protective effects of alpha lipoic acid on methotrexate induced testis injury in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Animals; Antioxidants; Catalase; Epithelial Cells; Glutathione Peroxidase; Male; Malondialdehyde; Methotrexate; Oxidants; Peroxidase; Protective Agents; Rats, Wistar; Seminiferous Tubules; Spermatogenesis; Superoxide Dismutase; Testis; Testosterone; Thioctic Acid

2018
Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Heme Oxygenase-1; Hepatic Stellate Cells; Inflammation; Liver; Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; Rats; Signal Transduction; Thioctic Acid

2018
Redox response, antibacterial and drug package capacities of chitosan-α-lipoic acid conjugates.
    International journal of biological macromolecules, 2020, Jul-01, Volume: 154

    Topics: Animals; Anti-Bacterial Agents; Cell Line, Tumor; Chitosan; Drug Carriers; Escherichia coli; Hydrogels; Methotrexate; Mice; Thioctic Acid

2020
Elucidation of the role of α-lipoic acid and vitamin C in methotrexate-induced hepatoxicity in mice.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Methotrexate; Mice; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Vitamins

2023