thioctic acid has been researched along with malondialdehyde in 144 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (4.86) | 18.2507 |
| 2000's | 40 (27.78) | 29.6817 |
| 2010's | 88 (61.11) | 24.3611 |
| 2020's | 9 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Augustin, W; Trümper, L; von Zglinicki, T; Wiswedel, I | 1 |
| Buhl, R; Freisleben, HJ; Fuchs, J; Grune, T; Milbradt, R; Schöfer, H; Siems, W | 1 |
| Scheer, B; Zimmer, G | 1 |
| Kähler, W; Kuklinski, B; Plötz, C; Rühlmann, C | 1 |
| Cooper, K; Ercal, N; Gurer, H; Kellogg, G; Neal, R | 1 |
| Ercal, N; Gurer, H; Ozgunes, H; Oztezcan, S | 1 |
| Bludovská, M; Eybl, V; Kotyzová, D; Koutenský, J | 1 |
| Husain, K; Malafa, M; Rybak, LP; Somani, SM; Trammell, GL; Whitworth, C | 1 |
| Fathallah, L; Frank, RN; Kennedy, A; Marinescu, V; Minchenko, AG; Obrosova, IG; Stevens, MJ; Stockert, CM | 1 |
| Craven, PA; DeRubertis, FR; Liachenko, J; Melhem, MF | 1 |
| Ames, BN; Bartholomew, JC; Hagen, TM; Ingersoll, RT; Liu, J; Lykkesfeldt, J; Vinarsky, V; Wehr, CM | 1 |
| Ames, BN; Killilea, DW; Liu, J | 1 |
| Freudenthaler, SM; Gleiter, CH; Pilz, J; Schreeb, KH; Wiese, A | 1 |
| Erşan, Y; Ozkan, Y; Oztürk, AI; Yildirim, M; Yilmaz, O | 1 |
| Fathallah, L; Liu, E; Nourooz-Zadeh, J; Obrosova, IG | 1 |
| Malarkodi, KP; Sandhya, S; Varalakshmi, P | 1 |
| Gupta, YK; Sharma, M | 1 |
| Cai, F; Gouty, S; Helke, CJ; Regalia, J | 1 |
| Asghar, M; Lokhandwala, MF | 1 |
| Prahalathan, C; Selvakumar, E; Varalakshmi, P | 1 |
| Bärtsch, P; Bierhaus, A; Nawroth, PP; Weiss, C | 1 |
| Husain, K; Rybak, LP; Somani, SM; Whitworth, C | 1 |
| Akbulut, HH; Akpolat, N; Celik, I; Cihangiroglu, M; Ilhan, N | 1 |
| Bobby, Z; Sathiyapriya, V; Selvaraj, N | 1 |
| Brown, L; Coombes, JS; Fassett, RG; Fenning, A; Lexis, LA | 1 |
| Cui, X; Hu, Y; Li, X; Liu, J; Long, J; Packer, L; Zhang, Q; Zuo, P | 1 |
| Coombes, JS; Marsh, SA | 1 |
| Anzai, K; Manda, K; Moritake, T; Ueno, M | 1 |
| Dulundu, E; Ercan, F; Gedik, N; Ozel, Y; Sehirli, O; Sener, G; Topaloglu, U | 1 |
| Aydogdu, N; Birtane, M; Dokmeci, D; Erbas, H; Tastekin, N; Ture, M; Usta, U | 1 |
| Alican, I; Ercan, F; Jahovic, N; Kolgazi, M; Yüksel, M | 1 |
| Basarali, K; Büyükbas, S; Cosar, E; Köken, G; Sahin, FK; Toy, H | 1 |
| May, JM; Sabharwal, AK | 1 |
| Aytekin, M; Caylak, E; Halifeoglu, I | 1 |
| Gong, DX; Jiang, YJ; Kong, CZ; Liu, HB; Sun, ZX; Yang, CM | 1 |
| Chen, XT; Liu, J; Ruan, DY; Tang, ML; Wang, HL; Wu, CY; Yin, ST | 1 |
| Aseĭchev, AV; Azizova, OA; Baranova, OA; Bekman, EM; Fedin, AI; Mironova, OP; Solov'eva, EIu | 1 |
| Arnal, E; Bosch-Morell, F; Diaz-Llopis, M; Garcia-Delpech, S; Garcia-Pous, M; Johnsen-Soriano, S; Miranda, M; Navea, A; Romero, FJ; Sancho-Tello, M | 1 |
| Cighetti, G; Pinelli, A; Trivulzio, S | 2 |
| Ames, BN; Cotman, CW; Gao, F; Liu, J; Long, J; Tong, L | 1 |
| Güven, A; Korkmaz, A; Kul, M; Ongürü, O; Oter, S; Sarici, U; Topal, T; Tunc, T | 1 |
| Chae, CH; Kim, HT; Shin, CH | 1 |
| Benfato, MS; Manfredini, V; Martins, VD; Peralba, MC | 1 |
| Choi, MG; Ihm, SH; Kang, JG; Kim, CS; Kim, DS; Kim, TW; Lee, SJ; Ryu, OH; Yoo, HJ | 1 |
| Atalay, M; Hyyppä, S; Jakus, J; Kinnunen, S; Laaksonen, DE; Oksala, N; Radak, Z; Sen, CK; Szabó, B | 1 |
| Berkman, MZ; Cetinel, S; Erşahin, M; Erzik, C; Sener, G; Toklu, HZ; Yeğen, BC; Yüksel, M | 1 |
| Dadhania, VP; Jena, GB; Ramarao, P; Tripathi, DN; Vikram, A | 1 |
| Li, CJ; Li, MZ; Yu, DM; Yu, P; Zhang, JY; Zhang, QM | 1 |
| Birkner, E; Kasperczyk, A; Kasperczyk, S; Wielkoszyński, T; Zalejska-Fiolka, J | 1 |
| Ciğremiş, Y; Karaman, M; Onder, F; Ozcan, K; Ozen, H; Tuzcu, M | 1 |
| Abdin, AA; Balaha, MF; El-Hamid, MA; El-Seoud, SH | 1 |
| Banerjee, S; Baxi, D; Joshi, N; Mukherjee, R; Ramachandran, AV; Singh, PK | 1 |
| Akakin, D; Biber, N; Celik, H; Cetinel, S; Cikler, E; Ersahin, M; Erzik, C; Hakan, T; Ogunc, AV; Sener, G; Toklu, HZ | 1 |
| Coombes, JS; Marsh, SA; Matsumoto, A; Peake, JM; Strobel, NA; Wadley, GD | 1 |
| Bilska, A; Iciek, M; Lorenc-Koci, E; Sokołowska, MM; Wlodek, LB | 1 |
| Ebied, S; Hussein, N; Mohasseb, M; Yehia, MA | 1 |
| Goto, K; Hagiwara, S; Kai, S; Koga, H; Kusaka, J; Noguchi, T; Shingu, C; Uchino, T | 1 |
| Abad, GD; Ghabili, K; Hajipour, B; Hemmati, MR; Khodadadi, A; Somi, MH; Vatankhah, AM | 1 |
| Li, KH; Lu, BB | 1 |
| Leggett, RE; Levin, RM; Radu, F; Schuler, C | 1 |
| Han, P; He, B; Li, S; Li, Y; Liu, L; Liu, Y; Lu, Y; Wu, N; Zhang, Y; Zhao, S | 1 |
| Ersöz, N; Korkmaz, A; Öter, Ş; Özerhan, İH; Özler, M; Topal, T | 1 |
| Khabbazi, T; Mahdavi, R; Pour-Abdollahi, P; Safa, J | 1 |
| Abdalla, AM; Abdelwahab, SA; Mahmoud, AM; Mahmoud, ME; Morsy, MA | 1 |
| Hagiwara, S; Inomata, M; Iwashita, Y; Kitano, S; Masuda, T; Noguchi, T; Ohta, M | 1 |
| Aleksandra, U; Goran, P; Jelena, A; Jelena, M; Melita, V; Mirjana, M; Nevena, G; Svetlana, D | 1 |
| Erdi, MF; Esen, H; Guney, O; Kiyici, A | 1 |
| Dai, Z; He, L; Liu, B; Luo, XJ; Ma, QL; Peng, J; Zhang, HF; Zhang, YS | 1 |
| Chen, P; Ji, C; Jie, YZ; Ma, QG; Zhang, JY; Zhang, Y; Zhao, LH | 1 |
| Cui, J; Le, GW; Shi, YH; Wang, B; Xiao, Y | 1 |
| Chen, SC; Liu, N; Song, GY; Zhang, DM | 1 |
| Bai, YL; Dong, YD; Fan, R; Jia, LH; Sun, YD; Zhai, LL | 1 |
| Banks, WA; Ercal, N; Farr, SA; Morley, JE; Price, TO | 1 |
| Carvalho, AF; Cordeiro, RC; Hyphantis, TN; Macêdo, DS; McIntyre, RS; Medeiros, CD; Morais, TA; Quevedo, J; Santos, JV; Sousa, FC | 1 |
| Fjeldstad, AS; Ives, SJ; McDaniel, J; Nativi, JN; Richardson, RS; Stehlik, J; Witman, MA; Wray, DW; Zhao, J | 1 |
| Al Abdan, M | 1 |
| Cassano, R; Ferrarelli, T; Leta, S; Picci, N; Puoci, F; Trombino, S | 1 |
| Bagrıyanık, A; Cavdar, Z; Erbil, G; Ergur, BU; Ozbal, S; Tekmen, I | 1 |
| Eguchi, H; Inomata, M; Iwashita, Y; Kawano, Y; Kitano, S; Ohta, M | 1 |
| Jalali-Nadoushan, M; Roghani, M | 1 |
| Abdel-Hady, RH; Abdel-Zaher, AO; Farghaly, HS; Hamdy, MM; Mostafa, MG | 1 |
| Azimi, A; Eghtesadi, S; Eskandari, G; Khalili, M; Mirshafiey, A; Moftakhar, S; Motevalian, A; Norouzi, A; Sahraian, MA; Sanoobar, M | 1 |
| Feng, B; Wang, H; Xu, L; Xue, JL; Yan, XF | 1 |
| Al-Ajmi, H; Al-Amin, M; Al-Rasheed, NM; Attia, HA; Hasan, IH; Mohamad, RA | 1 |
| Chen, YT; He, CT; Hsieh, PS; Tian, YF | 1 |
| Jia, SB; Li, Y; Liu, YZ; Shi, JM | 1 |
| Albayrak, A; Bilen, S; Fadillioglu, E; Ginis, Z; Kurt, SN; Ozturk, G | 1 |
| Chen, A; Deng, W; Fang, D; Huang, Z; Li, H; Li, Y; Liu, J; Liu, L; Wan, X; Wei, G | 1 |
| Inomata, M; Iwashita, Y; Kawano, Y; Kitano, S; Komori, Y; Ohta, M | 1 |
| Ahmadi, A; Hasanzade, J; Mazloom, Z; Mazooji, N; Roozbeh, J | 1 |
| Leelarungrayub, D; Thamprasert, K; Wongmekiat, O | 1 |
| Andrade, AS; Behling, CS; Benfato, MS; Hackenhaar, FS; Mahl, CD; Putti, J; Salomon, TB | 1 |
| Barakat, W; El-Moselhy, MA; Elshazly, SM | 1 |
| Akhtar, S; Anjum, FM; Arshad, MS; Khan, MI; Shahid, M; Sohaib, M | 1 |
| Duan, GX; Ji, C; Li, Y; Ma, QG; Wei, H; Zhang, JY; Zhao, LH | 1 |
| Ide, T | 1 |
| Abdel-Daim, MM; Abdou, RH | 1 |
| de Luka, S; Jorgacevic, B; Mladenovic, D; Radosavljevic, T; Stevanovic, I; Veskovic, M | 1 |
| Chen, W; Cheng, L; Li, Q; Tang, H; Wu, Y; Zhong, S | 1 |
| Asci, H; Bayram, D; Candan, IA; Cankara, FN; Ilhan, I; Saygin, M; Yesilot, S | 1 |
| Erdal, S; Gorcek, Z | 1 |
| Deng, Y; Feng, S; Li, YH; Liu, W; Xu, B; Xu, ZF; Yang, TY | 1 |
| Deng, H; Ji, A; Liu, L; Liu, X; Wu, Z; Xu, Q; Zhang, J; Zuo, X | 1 |
| Ascı, H; Dıncoglu, D; Gunes, A; Ozmen, O; Saygın, M; Tok, L; Tok, O | 1 |
| Allahverdi, E; Deprem, T; Diken Allahverdi, T; Günerhan, Y; Köksal, N; Merhan, O; Sülü, B; Vural, S; Yayla, S | 1 |
| Akçalı, N; Terzi, H; Yıldız, M | 1 |
| Aslaner, A; Baştürk, A; Çakır, T; Durgut, H; Gül, M; Gül, S; Öğünç, AV; Oruç, MT; Polat, C; Sabuncuoglu, MZ; Şehirli, AÖ | 1 |
| de Lucena, DF; de Sousa, CN; Gama, CS; Lima, LL; Macêdo, D; Oliveira, Tde Q; Vasconcelos, GS; Vasconcelos, SM; Ximenes, NC | 1 |
| Aslaner, A; Aykaç, A; Bahar, L; Baştürk, A; Çakır, T; Durgut, H; Gül, M; Polat, C; Sabuncuoglu, MZ; Şehirli, AÖ | 1 |
| Abdel-Galil, AG; El-Gowelli, HM; Ibrahim, ER; Saad, EI | 1 |
| Ding, Y; Le, G; Li, Z; Shi, Y; Zhao, Q | 1 |
| Armağan, I; Arslan, B; Bayram, D; Çiçek, E; Yeşilot, Ş; Yıldırım Baş, F; Yorgancıgil, E | 1 |
| Hu, H; Jin, Y; Liu, K; Liu, Q; Meng, Q; Sun, H; Wang, C | 1 |
| Gozeler, MS; Halici, Z; Korkmaz, H; Korkmaz, M; Mutlu, V; Selli, J; Tatar, A; Uslu, H; Yayla, M | 1 |
| Andreazza, AC; Fletcher, PJ; Lister, J; Navaid, B; Nesarajah, Y; Nobrega, JN; Remington, G; Teo, C; Wilson, AA; Wilson, VS | 1 |
| Bai, J; Li, J; Li, S; Lu, M; Sun, Q; Tang, X; Wang, G; Wei, F; Xu, B; Yin, Q; Zhang, H | 1 |
| Almansa Frias, MI; Benlloch-Navarro, MS; Broccoli, V; Garcia-Esparza, MA; Miranda, M; Paradells-Navarro, S; Soria, JM | 1 |
| Gunes, M; Ozkaya, A; Sahin, Z; Yilmaz, O; Yuce, A | 1 |
| Arpag, H; Atilla, N; Aydemir, Y; Cakir, T; Gül, M; Polat, C; Sayan, M; Yiğitcan, B; Þehirli, Ö | 1 |
| Błaszczyk, U; Cichoń, M; Zalejska-Fiolka, J | 1 |
| Al-Omair, MA; Al-Otaibi, L; Elsawy, H; Sedky, A | 1 |
| Ide, T; Tanaka, A | 1 |
| Gadjeva, V; Hristakieva, E; Karamalakova, Y; Lavcheva, R; Nikolova, G; Zheleva, A | 1 |
| Benfato, MS; Engers, VK; Hackenhaar, FS; Heemann, FM; Mena Canata, DA; Putti, JS; Salomon, TB; Schüller, ÁK | 1 |
| Hussein, RM; Mehany, ABM; Mohamed, WR | 1 |
| Chen, S; Cui, H; Liu, G; Long, M; Zou, H | 1 |
| Ambali, SF; Ayo, JO; Esievo, KAN; Uchendu, C | 1 |
| Çakırca, G; Kaplan, M; Özgür, T; Pınar, N | 1 |
| Aslfalah, H; Jamilian, M; Khosrowbeygi, A | 1 |
| Asghari-Jafarabadi, M; Hajalilou, M; Khabbazi, A; Kolahi, S; Mesgari Abbasi, M; Mirtaheri, E; Pourghasem Gargari, B | 1 |
| Aragón, CG; Baliño, P; Muriach, M; Romero-Cano, R; Sánchez-Andrés, JV; Valls, V | 1 |
| Atalay, E; Erdogdu, HI; Ozdemir, MT; Sisman, P; Tur, BK | 1 |
| Cheng, S; Ma, L; Wang, L; Xiang, W; Zhou, Y | 1 |
| Abdel-Hamed, EMW; Abdo, AIE; Desoky, EM; Elrys, AS | 1 |
| Aniss, NN; Motelp, BAAE; Zaazaa, AM | 1 |
| Bai, J; Gu, L; Han, Z; Li, S; Zhang, Q | 1 |
| Abdelhalim, MAK; Al-Mohy, YH; Ghannam, MM; Qaid, HA | 1 |
| Ibrahim Fouad, G; R Mousa, M | 1 |
| Ali, M; Baazeem, A; Brestic, M; El Sabagh, A; Faheem, M; Iqbal, MM; Javeed, HMR; Mubeen, M; Nawaz, F; Qamar, R; Rahman, MHU; Rehman, AU; Skalicky, M; Vachova, P | 1 |
| Alavi Naeini, A; Askari, G; Heidari, Z; Khorvash, F; Rezaei Kelishadi, M | 1 |
| Abdulla, MS; Hosny, EN; Khadrawy, YA; Khoder, NM; Sawie, HG; Sharada, HM | 1 |
| Cheng, X; Feng, J; Gao, W; Gong, Y; Lang, Y; Li, T; Liu, Y; Ning, M; Qi, B; Qi, Z; Wang, Y; Zheng, Y | 1 |
| Bayraktar, HS; Dirican, E; Dogan Ozcil, M; Hakverdi, S; Kacmaz, F; Ozcan, O | 1 |
15 trial(s) available for thioctic acid and malondialdehyde
| Article | Year |
|---|---|
Studies on lipoate effects on blood redox state in human immunodeficiency virus infected patients.
Topics: Adult; Antioxidants; HIV Infections; HIV Seropositivity; Humans; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Pilot Projects; Thioctic Acid | 1993 |
[Diabetes mellitus--a free radical-associated disease. Results of adjuvant antioxidant supplementation].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Female; Glycated Hemoglobin; Humans; Lipids; Male; Malondialdehyde; Middle Aged; Neurologic Examination; Oxygen; Selenium; Sodium Selenite; Thioctic Acid; Vitamin E | 1993 |
Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans.
Topics: Acetylcysteine; Adult; Antioxidants; Area Under Curve; Erythropoietin; Free Radical Scavengers; Humans; Hypoxia; Male; Malondialdehyde; Thioctic Acid | 2002 |
[The free-radical processes and antioxidant therapy in brain ischemia].
Topics: Aged; Antioxidants; Brain Ischemia; Drug Administration Schedule; Female; Free Radicals; Humans; Male; Malondialdehyde; Middle Aged; Thioctic Acid | 2008 |
Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients.
Topics: Adult; Anemia, Sickle Cell; Antioxidants; Biomarkers; Catalase; Dietary Supplements; Female; Follow-Up Studies; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Oxidative Stress; Proteins; Sickle Cell Trait; Superoxide Dismutase; Thioctic Acid; Young Adult | 2009 |
Amelioration of lipid abnormalities by α-lipoic acid through antioxidative and anti-inflammatory effects.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Glucose Intolerance; Humans; Insulin Resistance; Interleukin-6; Lipids; Malondialdehyde; Middle Aged; Obesity; Oxidative Stress; Prostaglandins; Thioctic Acid; Tumor Necrosis Factor-alpha | 2011 |
Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis.
Topics: Adult; Aged; Antioxidants; C-Reactive Protein; Cholesterol; Dietary Supplements; Double-Blind Method; Female; Humans; Inflammation; Iran; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Renal Dialysis; Thioctic Acid; Triglycerides; Young Adult | 2012 |
Effect of (R)-α-lipoic acid supplementation on serum lipids and antioxidative ability in patients with age-related macular degeneration.
Topics: Administration, Oral; Aged; Antioxidants; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; Female; Humans; Lipid Peroxidation; Lipoproteins, LDL; Macular Degeneration; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Risk Factors; Superoxide Dismutase; Thioctic Acid; Triglycerides | 2012 |
A differing role of oxidative stress in the regulation of central and peripheral hemodynamics during exercise in heart failure.
Topics: Administration, Oral; Antioxidants; Arterial Pressure; Ascorbic Acid; Biomarkers; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Exercise; Hand Strength; Heart Failure; Hemodynamics; Humans; Male; Malondialdehyde; Middle Aged; Muscle Contraction; Muscle, Skeletal; Oxidative Stress; Regional Blood Flow; Single-Blind Method; Superoxide Dismutase; Thioctic Acid; Time Factors; Ultrasonography, Doppler; Utah; Vascular Resistance; Vitamin E | 2012 |
Effect of lipoic acid consumption on oxidative stress among multiple sclerosis patients: a randomized controlled clinical trial.
Topics: Adolescent; Adult; Antioxidants; Biomarkers; Double-Blind Method; Female; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Middle Aged; Multiple Sclerosis; Oxidative Stress; Superoxide Dismutase; Thioctic Acid; Young Adult | 2014 |
Short-term continuous subcutaneous insulin infusion combined with insulin sensitizers rosiglitazone, metformin, or antioxidant α-lipoic acid in patients with newly diagnosed type 2 diabetes mellitus.
Topics: Adult; Aged; Antioxidants; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Insulin-Secreting Cells; Lipids; Male; Malondialdehyde; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones; Thioctic Acid; Time Factors | 2013 |
Effect of alpha-lipoic acid and vitamin E supplementation on oxidative stress, inflammation, and malnutrition in hemodialysis patients.
Topics: Adult; Antioxidants; C-Reactive Protein; Dietary Supplements; Female; Humans; Inflammation; Interleukin-6; Male; Malnutrition; Malondialdehyde; Middle Aged; Oxidative Stress; Renal Dialysis; Thioctic Acid; Treatment Outcome; Vitamin E | 2013 |
Elevation of the adiponectin/leptin ratio in women with gestational diabetes mellitus after supplementation with alpha-lipoic acid.
Topics: Adiponectin; Adult; Antioxidants; Blood Glucose; Diabetes, Gestational; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin Resistance; Leptin; Malondialdehyde; Oxidative Stress; Pregnancy; Thioctic Acid; Treatment Outcome | 2019 |
Oral administration of alpha-lipoic acid did not affect lipid peroxidation and antioxidant biomarkers in rheumatoid arthritis patients.
Topics: Administration, Oral; Antioxidants; Arthritis, Rheumatoid; Biomarkers; Glutathione Peroxidase; Humans; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Superoxide Dismutase; Thioctic Acid | 2019 |
The efficacy of alpha-lipoic acid in improving oxidative, inflammatory, and mood status in women with episodic migraine in a randomised, double-blind, placebo-controlled clinical trial.
Topics: Antioxidants; Biomarkers; C-Reactive Protein; Dietary Supplements; Double-Blind Method; Female; Humans; Malondialdehyde; Migraine Disorders; Oxidative Stress; Thioctic Acid | 2021 |
129 other study(ies) available for thioctic acid and malondialdehyde
| Article | Year |
|---|---|
Morphological changes of isolated rat liver mitochondria during Fe2+/ascorbate-induced peroxidation and the effect of thioctacid.
Topics: Animals; Ascorbic Acid; Ferrous Compounds; In Vitro Techniques; Lipid Peroxidation; Malondialdehyde; Mitochondria, Liver; Rats; Thioctic Acid | 1991 |
Dihydrolipoic acid prevents hypoxic/reoxygenation and peroxidative damage in rat heart mitochondria.
Topics: Animals; Cyclic N-Oxides; Diphenylhexatriene; Disulfides; Dithiothreitol; Electron Spin Resonance Spectroscopy; Fluorescence Polarization; Hydrogen Peroxide; Intracellular Membranes; Lipid Peroxidation; Male; Malondialdehyde; Membrane Fluidity; Mitochondria, Heart; Oxygen; Pyrrolidines; Rats; Rats, Inbred Strains; Rats, Wistar; Spin Labels; Thioctic Acid; Tiopronin | 1993 |
Effects of some sulfur-containing antioxidants on lead-exposed lenses.
Topics: Animals; Antioxidants; Captopril; Cysteine; Glutathione; Glutathione Disulfide; Lead; Lens, Crystalline; Lipid Peroxides; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species; Sulfur; Taurine; Thioctic Acid | 1999 |
Antioxidant role of alpha-lipoic acid in lead toxicity.
Topics: Animals; Antioxidants; Catalase; CHO Cells; Cricetinae; Glucosephosphate Dehydrogenase; Glutathione; Lead; Lead Poisoning; Malondialdehyde; Rats; Rats, Inbred F344; Thioctic Acid | 1999 |
The influence of alpha-lipoic acid on the toxicity of cadmium.
Topics: Animals; Antioxidants; Brain; Cadmium; Glutathione; Glutathione Peroxidase; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Testis; Thiobarbituric Acid Reactive Substances; Thioctic Acid; Tissue Distribution | 1999 |
Dose-dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system.
Topics: Animals; Antineoplastic Agents; Antioxidants; Catalase; Cisplatin; Creatinine; Dose-Response Relationship, Drug; Glutathione Peroxidase; Glutathione Reductase; Injections, Intraperitoneal; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Malondialdehyde; Platinum; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2000 |
Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats.
Topics: Alternative Splicing; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Dehydroascorbic Acid; Diabetes Mellitus, Experimental; Endothelial Growth Factors; Fructose; Gene Expression Regulation; Glucose; Glutathione; Lipid Peroxidation; Lymphokines; Malondialdehyde; Rats; Retina; RNA, Messenger; Sorbitol; Taurine; Thioctic Acid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Mesangium; Glutathione; Hyperglycemia; Hypoglycemic Agents; Kidney Cortex; Malondialdehyde; Rats; Renal Insufficiency; Thioctic Acid; Transforming Growth Factor beta | 2002 |
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.
Topics: Acetylcarnitine; Age Factors; Animals; Antioxidants; Ascorbic Acid; Fluoresceins; Hepatocytes; Lipid Peroxidation; Male; Malondialdehyde; Nootropic Agents; Oxidative Stress; Oxygen; Protein Binding; Rats; Rats, Inbred F344; Thioctic Acid; Time Factors | 2002 |
Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.
Topics: Acetylcarnitine; Aging; Aldehydes; Animals; Antioxidants; Brain; Breast; Carnitine O-Acetyltransferase; Columbidae; Cross-Linking Reagents; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Nootropic Agents; Oxygen; Protein Binding; Rats; Rats, Inbred F344; Spectrophotometry; Substrate Specificity; Thioctic Acid | 2002 |
Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Cholesterol; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Fish Oils; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Thioctic Acid; Triglycerides | 2002 |
Early oxidative stress in the diabetic kidney: effect of DL-alpha-lipoic acid.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus; F2-Isoprostanes; Kidney Cortex; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Thioctic Acid | 2003 |
Evaluation of the effect of lipoic acid administered along with gentamicin in rats rendered bacteremic.
Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Antioxidants; Bacteremia; Catalase; Escherichia coli; Gentamicins; Glutathione Peroxidase; Kidney; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2003 |
Effect of alpha lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Avoidance Learning; Behavior, Animal; Brain; Brain Chemistry; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Injections, Intraventricular; Male; Malondialdehyde; Maze Learning; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Reaction Time; Streptozocin; Thioctic Acid | 2003 |
Alpha-lipoic acid treatment prevents the diabetes-induced attenuation of the afferent limb of the baroreceptor reflex in rats.
Topics: Afferent Pathways; Animals; Baroreflex; Diabetes Mellitus, Experimental; Genes, fos; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Thioctic Acid | 2003 |
Antioxidant supplementation normalizes elevated protein kinase C activity in the proximal tubules of old rats.
Topics: Aging; Animals; Antioxidants; Cyclic N-Oxides; Dietary Supplements; Kidney Tubules, Proximal; Male; Malondialdehyde; Oxidative Stress; Protein Kinase C; Rats; Rats, Inbred F344; Sodium-Potassium-Exchanging ATPase; Spin Labels; Thioctic Acid | 2004 |
Remedial effect of DL-alpha-lipoic acid against adriamycin induced testicular lipid peroxidation.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Catalase; Doxorubicin; Enzymes; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Injections, Intravenous; Lipid Peroxidation; Male; Malondialdehyde; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Testis; Thioctic Acid | 2004 |
Effects of supplementation with alpha-lipoic acid on exercise-induced activation of coagulation.
Topics: Adult; Blood Coagulation; Dietary Supplements; Exercise; Fibrinolysis; Homeostasis; Humans; Male; Malondialdehyde; Thioctic Acid | 2005 |
Partial protection by lipoic acid against carboplantin-induced ototoxicity in rats.
Topics: Animals; Antioxidants; Auditory Threshold; Carboplatin; Catalase; Cochlea; Evoked Potentials, Auditory, Brain Stem; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hearing Loss, Sensorineural; Lipid Peroxidation; Male; Malondialdehyde; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2005 |
Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity.
Topics: Amrinone; Animals; Anti-Bacterial Agents; Antioxidants; Female; Free Radicals; Ginkgo biloba; Glutathione Peroxidase; Kidney Cortex; Kidney Diseases; Kidney Function Tests; Malondialdehyde; Melatonin; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioctic Acid; Vancomycin | 2005 |
Effect of lipid peroxides and antioxidants on glycation of hemoglobin: an in vitro study on human erythrocytes.
Topics: Antioxidants; Dose-Response Relationship, Drug; Erythrocytes; Glucose; Glycated Hemoglobin; Humans; Lipid Peroxides; Malondialdehyde; Taurine; Thioctic Acid | 2006 |
Antioxidant supplementation enhances erythrocyte antioxidant status and attenuates cyclosporine-induced vascular dysfunction.
Topics: alpha-Tocopherol; Animals; Antioxidants; Aorta, Thoracic; Creatinine; Cyclosporine; Dietary Supplements; Erythrocytes; Glutathione; Immunosuppressive Agents; Male; Malondialdehyde; Methemoglobin; Rats; Rats, Sprague-Dawley; Superoxides; Thioctic Acid; Vascular Diseases | 2006 |
Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Caspases; Dementia; Disease Models, Animal; Galactose; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Superoxide Dismutase; Thioctic Acid | 2006 |
Vitamin E and alpha-lipoic acid supplementation increase bleeding tendency via an intrinsic coagulation pathway.
Topics: Animals; Antioxidants; Blood Coagulation; Dietary Supplements; Drug Therapy, Combination; Hemorrhage; Lipid Peroxidation; Male; Malondialdehyde; Partial Thromboplastin Time; Prothrombin Time; Rats; Thioctic Acid; Vitamin E | 2006 |
alpha-Lipoic acid attenuates x-irradiation-induced oxidative stress in mice.
Topics: Animals; Antioxidants; Free Radical Scavengers; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Oxidative Stress; Radiation-Protective Agents; Sulfhydryl Compounds; Thioctic Acid | 2007 |
Alpha-lipoic acid protects against hepatic ischemia-reperfusion injury in rats.
Topics: Acridines; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Glutathione; Hepatocytes; Interleukin-1beta; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Luminol; Male; Malondialdehyde; Microscopy, Polarization; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Thioctic Acid; Tumor Necrosis Factor-alpha | 2007 |
Protective effects of L-carnitine and alpha-lipoic acid in rats with adjuvant arthritis.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Experimental; Carnitine; Diclofenac; Freund's Adjuvant; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioctic Acid; Tumor Necrosis Factor-alpha | 2007 |
Alpha-lipoic acid modulates gut inflammation induced by trinitrobenzene sulfonic acid in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Disease Models, Animal; Gastrointestinal Agents; Glutathione; Ileitis; Ileum; Lipid Peroxidation; Malondialdehyde; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thioctic Acid; Trinitrobenzenesulfonic Acid | 2007 |
The protective effect of alpha-lipoic acid in experimental ovarian ischaemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; Female; Malondialdehyde; Nitric Oxide; Ovary; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Thioctic Acid; Xanthine Oxidase | 2007 |
alpha-Lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells.
Topics: alpha-Tocopherol; Ascorbic Acid; Cells, Cultured; Cholesterol, LDL; Copper; Endothelial Cells; Extracellular Space; Glutathione; Humans; Intracellular Space; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Thioctic Acid; Time Factors; Vitamin K 3 | 2008 |
Antioxidant effects of methionine, alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Erythrocytes; Glutathione Peroxidase; Hemoglobins; Homocystine; Lead; Male; Malondialdehyde; Methionine; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Vitamin A; Vitamin E | 2008 |
Ability of alpha-lipoic acid to reverse the diabetic cystopathy in a rat model.
Topics: Animals; Antioxidants; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Nerve Growth Factor; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioctic Acid; Urinary Bladder; Urinary Bladder Diseases | 2008 |
Opposite effects of alpha-lipoic acid on antioxidation and long-term potentiation in control and chronically lead-exposed rats.
Topics: Animals; Antioxidants; Electrophysiology; Glutathione; Hippocampus; Injections, Intraperitoneal; Lead; Lead Poisoning, Nervous System; Long-Term Potentiation; Malondialdehyde; Membrane Potentials; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2008 |
Early lipoic acid intake protects retina of diabetic mice.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drug Administration Schedule; Electroretinography; Glutathione; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Mice; Oxidative Stress; Retina; Thioctic Acid | 2008 |
Plasma malondialdehyde levels and opiate withdrawal signs observed in rats treated with morphine plus naloxone: effects of alpha-lipoic acid administration.
Topics: Animals; Antioxidants; Behavior, Animal; Defecation; Dose-Response Relationship, Drug; Drug Interactions; Gas Chromatography-Mass Spectrometry; Male; Malondialdehyde; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Oxidative Stress; Pain Threshold; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Thioctic Acid | 2008 |
Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.
Topics: Acetylcarnitine; Aging; Animals; Brain; Catalase; Electron Transport Chain Complex Proteins; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Oxidative Stress; Protein Carbonylation; Rats; Rats, Inbred F344; Stereoisomerism; Superoxide Dismutase; Thioctic Acid | 2009 |
Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.
Topics: Acetylcysteine; Animals; Antioxidants; Constriction; Disease Models, Animal; Glutathione Peroxidase; Ileum; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sexual Development; Sulfhydryl Compounds; Superoxide Dismutase; Thioctic Acid; Thioglycolates; Thiophenes | 2009 |
The combination of alpha-lipoic acid supplementation and aerobic exercise inhibits lipid peroxidation in rat skeletal muscles.
Topics: Animals; Antioxidants; Dietary Supplements; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Muscle, Skeletal; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioctic Acid; Vitamin E | 2008 |
Effects of alpha-lipoic acid administration on plasma glucose levels, total malondialdehyde values and withdrawal signs in rats treated with morphine or morphine plus naloxone.
Topics: Analgesics, Opioid; Animals; Antioxidants; Behavior, Animal; Blood Glucose; Defecation; Male; Malondialdehyde; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Thioctic Acid | 2009 |
Effects of alpha-lipoic acid on transforming growth factor beta1-p38 mitogen-activated protein kinase-fibronectin pathway in diabetic nephropathy.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Blood Glucose; Blotting, Western; Cholesterol; Diabetic Nephropathies; Fatty Acids, Nonesterified; Fibronectins; Glycated Hemoglobin; Insulin; Male; Malondialdehyde; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proteinuria; Random Allocation; Rats; Rats, Inbred OLETF; Signal Transduction; Specific Pathogen-Free Organisms; Thioctic Acid; Transforming Growth Factor beta1 | 2009 |
alpha-Lipoic acid modulates thiol antioxidant defenses and attenuates exercise-induced oxidative stress in standardbred trotters.
Topics: Animals; Dietary Supplements; Drug Evaluation, Preclinical; Electron Spin Resonance Spectroscopy; Exercise Test; Female; Glutathione; Horses; Lipid Peroxidation; Male; Malondialdehyde; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Physical Conditioning, Animal; Protein Carbonylation; Reactive Oxygen Species; Thioctic Acid; Thioredoxins | 2009 |
Alpha lipoic acid alleviates oxidative stress and preserves blood brain permeability in rats with subarachnoid hemorrhage.
Topics: Animals; Antioxidants; Basilar Artery; Behavior, Animal; Blood-Brain Barrier; Brain Edema; DNA Fragmentation; Evans Blue; Glutathione; Luminescence; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Permeability; Peroxidase; Rats; Rats, Wistar; Subarachnoid Hemorrhage; Thioctic Acid; Vasospasm, Intracranial | 2010 |
Intervention of alpha-lipoic acid ameliorates methotrexate-induced oxidative stress and genotoxicity: A study in rat intestine.
Topics: Alkaline Phosphatase; Animals; Antimetabolites, Antineoplastic; Comet Assay; DNA Damage; Glutathione; In Situ Nick-End Labeling; Intestines; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tumor Suppressor Protein p53 | 2010 |
Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy.
Topics: Animals; Apoptosis; Cardiomyopathies; Caspase 3; Caspase 9; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Male; Malondialdehyde; Mitochondria, Heart; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2009 |
Effects of oxidized cooking oil and α-lipoic acid on liver antioxidants: enzyme activities and lipid peroxidation in rats fed a high fat diet.
Topics: Animals; Antioxidants; Diet; Dietary Fats; Fatty Acids; Glutathione Reductase; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2010 |
Pathological, biochemical and haematological investigations on the protective effect of alpha-lipoic acid in experimental aflatoxin toxicosis in chicks.
Topics: Aflatoxins; Animals; Antioxidants; Apoptosis; Blood Cell Count; Chickens; Female; Hematocrit; Hemoglobins; Immunohistochemistry; In Situ Nick-End Labeling; Liver; Malondialdehyde; Nitric Oxide Synthase Type II; Poultry Diseases; Random Allocation; Thioctic Acid; Tyrosine | 2010 |
Effect of pentoxifylline and/or alpha lipoic acid on experimentally induced acute pancreatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Biomarkers; C-Reactive Protein; Drug Therapy, Combination; Free Radical Scavengers; Interleukin-6; Male; Malondialdehyde; Oxidative Stress; Pancreas; Pancreatitis, Acute Necrotizing; Pentoxifylline; Rats; Thioctic Acid; Time Factors | 2010 |
A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Cadmium Chloride; Drug Synergism; Drug Therapy, Combination; Enzymes; Female; Glutathione; Heart Diseases; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Malondialdehyde; Melatonin; Metallothionein; Myocardium; Oxidative Stress; Rats; Thioctic Acid; Vitamin E | 2011 |
Neuroprotective effects of alpha-lipoic acid in experimental spinal cord injury in rats.
Topics: Analysis of Variance; Animals; Disease Models, Animal; DNA Fragmentation; Glutathione; Luminescent Measurements; Male; Malondialdehyde; Neurologic Examination; Neuroprotective Agents; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Spinal Cord Injuries; Thioctic Acid | 2010 |
Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis.
Topics: Animals; Antioxidants; Biomarkers; Citrate (si)-Synthase; Cytochromes c; Electron Transport Complex IV; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria, Muscle; Muscle, Skeletal; NF-E2-Related Factor 2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA-Binding Proteins; RNA, Messenger; Superoxide Dismutase; Thioctic Acid; Transcription Factors; Vitamin E | 2011 |
The effect of uremic toxin cyanate (OCN–) on anaerobic sulfur metabolism and prooxidative processes in the rat kidney: a protective role of lipoate.
Topics: Animals; Antioxidants; Cyanates; Cysteine; Glutathione; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfur; Sulfurtransferases; Thioctic Acid; Thiosulfate Sulfurtransferase | 2011 |
Testicular oxidative damage and role of combined antioxidant supplementation in experimental diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Caspase 3; Diabetes Mellitus, Experimental; Dietary Supplements; Glutathione Peroxidase; Male; Malondialdehyde; Rats; Superoxide Dismutase; Testis; Thioctic Acid; Vitamin E | 2011 |
New α-lipoic acid derivative, DHL-HisZn, ameliorates renal ischemia-reperfusion injury in rats.
Topics: Acute Kidney Injury; Animals; Cell Line; Histidine; Kidney; Kidney Function Tests; Male; Malondialdehyde; Mice; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Thioctic Acid | 2012 |
Protective role of lipoic acid on methotrexate induced intestinal damage in rabbit model.
Topics: Animals; Antimetabolites, Antineoplastic; Glutathione Peroxidase; Intestinal Mucosa; Intestine, Small; Male; Malondialdehyde; Methotrexate; Models, Animal; Oxidative Stress; Protective Agents; Rabbits; Random Allocation; Superoxide Dismutase; Thioctic Acid | 2011 |
Lipoic acid prevents steroid-induced osteonecrosis in rabbits.
Topics: Animals; Biomarkers; Cholesterol; Cytoprotection; Disease Models, Animal; Endothelins; Femur; Glutathione; Lipoproteins, HDL; Lipoproteins, LDL; Male; Malondialdehyde; Methylprednisolone; Methylprednisolone Acetate; Osteonecrosis; Oxidative Stress; Protective Agents; Rabbits; Thioctic Acid; Time Factors | 2012 |
The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion.
Topics: Animals; Antioxidants; Fatty Acids, Nonesterified; Ischemia; Lipid Peroxidation; Male; Malondialdehyde; Mucous Membrane; Muscle, Smooth; Organ Size; Phospholipases A2; Phospholipids; Rabbits; Reperfusion Injury; Thioctic Acid; Ubiquinone; Urinary Bladder | 2011 |
The effect of alpha-lipoic acid in the prevention of peritoneal adhesions.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydroxyproline; Male; Malondialdehyde; Oxidative Stress; Peritoneum; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tissue Adhesions | 2011 |
Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Curcumin; gamma-Glutamyltransferase; Glutathione; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 13; Rats; Rats, Wistar; Thioctic Acid; Transforming Growth Factor alpha | 2012 |
Dihydrolipoyl histidinate zinc complex, a new antioxidant, attenuates hepatic ischemia-reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Antimycin A; Antioxidants; Aspartate Aminotransferases; Biomarkers; Biphenyl Compounds; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Histidine; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Oxidative Stress; Picrates; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Thioctic Acid; Time Factors | 2011 |
Alpha-lipoic acid preserves the structural and functional integrity of red blood cells by adjusting the redox disturbance and decreasing O-GlcNAc modifications of antioxidant enzymes and heat shock proteins in diabetic rats.
Topics: Acetylglucosamine; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutathione; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Iron; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Thioctic Acid | 2012 |
The effects of alpha lipoic acid on cerebral vasospasm following experimental subarachnoid hemorrhage in the rabbit.
Topics: Animals; Antioxidants; Apoptosis; Basilar Artery; Cerebrovascular Circulation; Disease Models, Animal; Endothelial Cells; Free Radicals; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hydrogen Peroxide; Male; Malondialdehyde; Muscle, Smooth, Vascular; Oxidative Stress; Rabbits; Subarachnoid Hemorrhage; Superoxide Dismutase; Thioctic Acid; Treatment Outcome; Vasodilation; Vasospasm, Intracranial | 2011 |
Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Apoptosis; Caspase 3; Cells, Cultured; Creatine Kinase; Disease Models, Animal; Heart; In Vitro Techniques; Male; Malondialdehyde; Mitochondrial Proteins; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thioctic Acid | 2012 |
Dietary lipoic acid influences antioxidant capability and oxidative status of broilers.
Topics: Animals; Antioxidants; Chickens; Dietary Supplements; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Muscle, Skeletal; Oxidative Stress; Superoxide Dismutase; Thioctic Acid | 2011 |
Lipoic acid attenuates high-fat-diet-induced oxidative stress and B-cell-related immune depression.
Topics: Animals; Antioxidants; Apoptosis; B-Lymphocytes; Catalase; Diet, High-Fat; Dietary Supplements; Gene Expression Profiling; Glutathione Peroxidase; Immune Tolerance; Immunoglobulin kappa-Chains; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neuropeptides; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Peroxiredoxins; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Reactive Oxygen Species; Receptors, Fc; Signal Transduction; Superoxide Dismutase; Thioctic Acid; Up-Regulation | 2012 |
[Alpha lipoic acid affect the function of EPCs incubated by high-glucose].
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation, Enzymologic; Glucose; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Stem Cells; Thioctic Acid | 2012 |
Effect of alpha-lipoic acid on memory, oxidation, and lifespan in SAMP8 mice.
Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Disease Models, Animal; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Longevity; Malondialdehyde; Maze Learning; Memory; Mice; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Thioctic Acid | 2012 |
Effects of alpha-lipoic acid in an animal model of mania induced by D-amphetamine.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Glutathione; Lipid Peroxidation; Lithium Chloride; Male; Malondialdehyde; Mice; Motor Activity; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2012 |
Alfa-lipoic acid controls tumor growth and modulates hepatic redox state in Ehrlich-ascites-carcinoma-bearing mice.
Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Ehrlich Tumor; Catalase; Cell Line, Tumor; Cell Survival; Female; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Neoplasm Transplantation; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Thioctic Acid | 2012 |
Preparation, characterization and efficacy evaluation of synthetic biocompatible polymers linking natural antioxidants.
Topics: Acrylamides; Acrylic Resins; Animals; Biocompatible Materials; Biphenyl Compounds; Caco-2 Cells; Cell Survival; Coumaric Acids; Free Radical Scavengers; Free Radicals; Humans; Inhibitory Concentration 50; Lipid Peroxidation; Malondialdehyde; Methacrylates; Microsomes, Liver; Picrates; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Thioctic Acid | 2012 |
The effects of α-lipoic acid against testicular ischemia-reperfusion injury in Rats.
Topics: Animals; Antioxidants; Caspase 3; In Situ Nick-End Labeling; Male; Malondialdehyde; Oxidative Stress; Rats; Reperfusion Injury; Spermatic Cord Torsion; Testicular Diseases; Thioctic Acid | 2012 |
Increased oxidative stress may lead to impaired adaptive cytoprotection in the gastric mucosa of portal hypertensive rat.
Topics: Adaptation, Physiological; Animals; Cytoprotection; Ethanol; Gastric Mucosa; Glutathione; Histidine; Hypertension, Portal; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tyrosine | 2013 |
Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism.
Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rotation; Substantia Nigra; Thioctic Acid | 2013 |
Role of oxidative stress and inducible nitric oxide synthase in morphine-induced tolerance and dependence in mice. Effect of alpha-lipoic acid.
Topics: Animals; Arginine; Brain; Drug Tolerance; Enzyme Inhibitors; Glutamic Acid; Glutathione; Indazoles; Male; Malondialdehyde; Mice; Morphine; Morphine Dependence; Nitric Oxide Synthase Type II; Oxidative Stress; Thioctic Acid | 2013 |
The protective effects of α-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Kidney; Male; Malondialdehyde; NADPH Oxidases; NF-kappa B; Organ Size; Oxidative Stress; Protective Agents; Proteinuria; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2013 |
Adverse cardiac responses to alpha-lipoic acid in a rat-diabetic model: possible mechanisms?
Topics: Animals; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Heart Failure; Male; Malondialdehyde; Myocardium; NADPH Oxidases; Oxidants; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Thioctic Acid; Triglycerides; Troponin I; Vascular Endothelial Growth Factor A | 2013 |
Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cytokines; Disease Models, Animal; Endotoxemia; Fatty Liver; Fructose; Glutathione; Inflammation Mediators; Insulin; Lipopolysaccharides; Liver; Male; Malondialdehyde; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Superoxides; Thioctic Acid; Toll-Like Receptor 4; Triglycerides | 2013 |
Alpha lipoic acid protects lens from H(2)O(2)-induced cataract by inhibiting apoptosis of lens epithelial cells and inducing activation of anti-oxidative enzymes.
Topics: Animals; Antioxidants; Apoptosis; Cataract; Epithelial Cells; Glutathione; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lens, Crystalline; Malondialdehyde; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioctic Acid | 2013 |
Effect of alpha lipoic acid on ifosfamide-induced central neurotoxicity in rats.
Topics: Animals; Antioxidants; Brain; Caspase 3; Catalase; Ifosfamide; Male; Malondialdehyde; Neurons; Neurotoxicity Syndromes; Protein Carbonylation; Rats; Thioctic Acid | 2014 |
Effects of the dihydrolipoyl histidinate zinc complex against carbon tetrachloride-induced hepatic fibrosis in rats.
Topics: Animals; Antimycin A; Antioxidants; Carbon Tetrachloride; Cells, Cultured; Glutathione; Hepatic Stellate Cells; Histidine; Humans; Liver; Liver Cirrhosis; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Thioctic Acid; Zinc Compounds | 2014 |
Alpha-lipoic acid attenuates renal injury in rats with obstructive nephropathy.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Creatinine; Glutathione; Kidney; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; Nitric Oxide; Organ Size; Rats; Rats, Sprague-Dawley; Thioctic Acid; Transforming Growth Factor beta1; Ureteral Obstruction | 2013 |
Alpha-lipoic acid restores tear production in an animal model of dry eye.
Topics: Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Conjunctiva; Cornea; Dietary Supplements; Disease Models, Animal; Dry Eye Syndromes; Epithelium, Corneal; Estradiol; Fatty Acids, Omega-3; Female; Glutathione; Lacrimal Apparatus; Malondialdehyde; Microscopy, Electron, Scanning; Nitrates; Nitrites; Ovariectomy; Oxidative Stress; Progesterone; Radioimmunoassay; Rats; Rats, Wistar; Tears; Thioctic Acid | 2014 |
Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytoprotection; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Thioctic Acid | 2014 |
Wheat germ oil enrichment in broiler feed with α-lipoic acid to enhance the antioxidant potential and lipid stability of meat.
Topics: alpha-Tocopherol; Animal Feed; Animals; Antioxidants; Biphenyl Compounds; Body Weight; Chickens; Dietary Supplements; Eating; Food Preservation; Gallic Acid; Humans; Male; Malondialdehyde; Meat; Muscle, Skeletal; Picrates; Plant Oils; Thioctic Acid | 2013 |
Effects of lipoic acid on immune function, the antioxidant defense system, and inflammation-related genes expression of broiler chickens fed aflatoxin contaminated diets.
Topics: Aflatoxin B1; Animal Feed; Animals; Antioxidants; Chickens; Diet; Dietary Supplements; Glutathione Peroxidase; Heme Oxygenase-1; Inflammation; Interferon-gamma; Interleukin-6; Male; Malondialdehyde; Oxidative Stress; Random Allocation; RNA, Messenger; Superoxide Dismutase; Thioctic Acid; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Effect of dietary α-lipoic acid on the mRNA expression of genes involved in drug metabolism and antioxidation system in rat liver.
Topics: Animals; Antioxidants; Diet; Gene Expression; Glutathione; Glutathione Reductase; Glutathione Transferase; Inactivation, Metabolic; Liver; Male; Malondialdehyde; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thioctic Acid | 2014 |
Alpha-lipoic acid improves acute deltamethrin-induced toxicity in rats.
Topics: Animals; Antioxidants; Biomarkers; Catalase; Free Radical Scavengers; Glutathione; Insecticides; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nitriles; Oxidative Stress; Pyrethrins; Rats; Superoxide Dismutase; Thioctic Acid | 2014 |
Alpha-lipoic acid affects the oxidative stress in various brain structures in mice with methionine and choline deficiency.
Topics: Animals; Brain; Catalase; Cerebral Cortex; Choline Deficiency; Corpus Striatum; Disease Models, Animal; Glutathione; Hippocampus; Hypothalamus; Lipid Peroxidation; Male; Malondialdehyde; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Thioctic Acid | 2015 |
Anti-neurotoxicity effects of oxoisoaporphine-lipoic acid hybrids.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Aporphines; Cell Line; Cholinesterase Inhibitors; Drosophila melanogaster; Humans; Malondialdehyde; Neuroprotective Agents; Peptide Fragments; Protein Aggregation, Pathological; Recombinant Proteins; Structure-Activity Relationship; Superoxide Dismutase; Thioctic Acid | 2014 |
The impact of alpha-lipoic acid on amikacin-induced nephrotoxicity.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Antioxidants; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Female; Kidney; Kidney Function Tests; Malondialdehyde; Rats; Rats, Wistar; Renal Insufficiency; Thioctic Acid; Treatment Outcome | 2015 |
Lipoic acid mitigates oxidative stress and recovers metabolic distortions in salt-stressed wheat seedlings by modulating ion homeostasis, the osmo-regulator level and antioxidant system.
Topics: Antioxidants; Calcium; Carbohydrate Metabolism; Chlorophyll; Homeostasis; Ions; Malondialdehyde; Osmoregulation; Oxidative Stress; Potassium; Proline; Ribulose-Bisphosphate Carboxylase; Salinity; Salt Tolerance; Seedlings; Sodium; Sodium Chloride; Stress, Physiological; Thioctic Acid; Triticum | 2015 |
Alpha-lipoic acid protects against methylmercury-induced neurotoxic effects via inhibition of oxidative stress in rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Environmental Pollutants; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Male; Malondialdehyde; Methylmercury Compounds; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Thioctic Acid | 2015 |
Α‑lipoic acid protects against cerebral ischemia/reperfusion-induced injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Brain Edema; Brain Ischemia; Brain-Derived Neurotrophic Factor; Caspases; Cerebral Infarction; Disease Models, Animal; Male; Malondialdehyde; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reperfusion Injury; Superoxide Dismutase; Thioctic Acid | 2015 |
Lens and cornea lesions of rats fed corn syrup and the protective effects of alpha lipoic acid.
Topics: Animals; Catalase; Cornea; Female; High Fructose Corn Syrup; Lens, Crystalline; Malondialdehyde; Protective Agents; Rats, Wistar; Thioctic Acid | 2016 |
Effects of alpha lipoic acid on intra-abdominal adhesion: an experimental study in a rat model.
Topics: Animals; Antioxidants; Cecum; Disease Models, Animal; Female; Glutathione; Infusions, Parenteral; Laparotomy; Malondialdehyde; Peritoneal Diseases; Rats; Rats, Wistar; Thioctic Acid; Tissue Adhesions | 2015 |
Proteomic and biochemical responses of canola (Brassica napus L.) exposed to salinity stress and exogenous lipoic acid.
Topics: Antioxidants; Ascorbate Peroxidases; Brassica napus; Catalase; Cysteine; Electrophoresis, Gel, Two-Dimensional; Glutathione; Malondialdehyde; Models, Biological; Peroxidase; Plant Leaves; Proline; Proteome; Proteomics; Salinity; Seedlings; Sodium Chloride; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stress, Physiological; Superoxide Dismutase; Thioctic Acid | 2015 |
Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats?
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Methotrexate; Necrosis; Peroxidase; Random Allocation; Rats, Wistar; Reproducibility of Results; Thioctic Acid; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and neurotrophic mechanisms.
Topics: Analysis of Variance; Animals; Antioxidants; Antipsychotic Agents; Brain; Brain-Derived Neurotrophic Factor; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutathione; Interpersonal Relations; Ketamine; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Mice; Nitrites; Random Allocation; Reflex, Startle; Schizophrenia; Thioctic Acid | 2015 |
The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Female; Glutathione; Interleukin-1beta; Kidney; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Thioctic Acid; Tumor Necrosis Factor-alpha | 2015 |
Co-administration of α-lipoic acid and cyclosporine aggravates colon ulceration of acetic acid-induced ulcerative colitis via facilitation of NO/COX-2/miR-210 cascade.
Topics: Acetic Acid; Animals; C-Reactive Protein; Catalase; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Cyclosporine; Dose-Response Relationship, Drug; Glutathione; Male; Malondialdehyde; MicroRNAs; Nitric Oxide; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2015 |
[Effects of tyrosine oxidation products on redox state in myocardium of rats].
Topics: Animals; Antioxidants; Catalase; Glutathione; Glutathione Peroxidase; Heart; Male; Malondialdehyde; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Thioctic Acid; Transcription Factor AP-1; Tyrosine | 2015 |
Effect of alpha lipoic acid on smoking-induced skin damage.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Female; Malondialdehyde; Protein Carbonylation; Rats, Sprague-Dawley; Reactive Oxygen Species; Skin; Smoking; Thioctic Acid; Tobacco Smoke Pollution; Tumor Necrosis Factor-alpha | 2017 |
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Topics: Aorta; Apoptosis; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endothelial Cells; Glutathione; Homocysteine; Humans; Intercellular Adhesion Molecule-1; L-Lactate Dehydrogenase; Malondialdehyde; Matrix Metalloproteinase 9; Models, Biological; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Thioctic Acid; Transcriptional Activation; Vascular Cell Adhesion Molecule-1 | 2016 |
Anti-inflammatory and anti-oxidative effects of alpha-lipoic acid in experimentally induced acute otitis media.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Antioxidants; Glutathione; Guinea Pigs; Malondialdehyde; Mucous Membrane; Otitis Media; Penicillin G; Pneumococcal Infections; Streptococcus pneumoniae; Superoxide Dismutase; Thioctic Acid; Tympanic Membrane | 2016 |
Lipoic acid and haloperidol-induced vacuous chewing movements: Implications for prophylactic antioxidant use in tardive dyskinesia.
Topics: Aldehydes; Analysis of Variance; Animals; Antioxidants; Antipsychotic Agents; Haloperidol; Male; Malondialdehyde; Mastication; Rats; Rats, Sprague-Dawley; Tardive Dyskinesia; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2017 |
Effects of alpha-lipoic acid supplementation on growth performance, antioxidant capacity and biochemical parameters for ammonia-exposed broilers.
Topics: Alanine Transaminase; Ammonia; Animals; Chickens; Creatine Kinase; Diet; Dietary Supplements; Environmental Exposure; Glutathione; Glutathione Peroxidase; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Serum Albumin; Stress, Physiological; Superoxide Dismutase; Thioctic Acid; Time Factors | 2017 |
Neuroprotection of Brain Cells by Lipoic Acid Treatment after Cellular Stress.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Buthionine Sulfoximine; Cerebral Cortex; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Glutathione; Lipopolysaccharides; Malondialdehyde; Mice; Mice, Inbred C57BL; Neurons; Oxidation-Reduction; Oxidative Stress; Thioctic Acid | 2017 |
Investigation of the role of α-lipoic acid on fatty acids profile, some minerals (zinc, copper, iron) and antioxidant activity against aluminum-induced oxidative stress in the liver of male rats.
Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Catalase; Chlorides; Copper; Fatty Acids; Glutathione; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Minerals; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Zinc | 2017 |
Protective Effects of Alpha-Lipoic Acid on Methotrexate-Induced Oxidative Lung Injury in Rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Glutathione; Humans; Interleukin-1beta; Lung; Lung Injury; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thioctic Acid; Tumor Necrosis Factor-alpha | 2018 |
[Effect of α-lipoic acid on free radical processes in serum of rats on high fat diet].
Topics: Animals; Antioxidants; Creatinine; Diet, High-Fat; Free Radicals; Lipid Peroxidation; Lipid Peroxides; Male; Malondialdehyde; Rats; Rats, Wistar; Thioctic Acid | 2017 |
Protective effect of α-lipoic acid against α-cypermethrin-induced changes in rat cerebellum.
Topics: Acetylcholinesterase; Animals; Antioxidants; Cerebellum; gamma-Aminobutyric Acid; Insecticides; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Pyrethrins; Rats; Rats, Wistar; Thioctic Acid | 2017 |
α-Lipoic acid ameliorated oxidative stress induced by perilla oil, but the combination of these dietary factors was ineffective to cause marked deceases in serum lipid levels in rats.
Topics: alpha-Linolenic Acid; Animals; Antioxidants; Cholesterol; Corn Oil; Dietary Fats; Lipid Metabolism; Liver; Male; Malondialdehyde; Oxidative Stress; Palm Oil; Plant Oils; Rats; Rats, Sprague-Dawley; Thioctic Acid; Triglycerides | 2017 |
Comparative study on some oxidative stress parameters in blood of vitiligo patients before and after combined therapy.
Topics: Antioxidants; Ascorbic Acid; Biomarkers; Catalase; Cysteine; Dietary Fats, Unsaturated; Female; Humans; Male; Malondialdehyde; Oxidative Stress; Phototherapy; Reactive Oxygen Species; Thiamine; Thioctic Acid; Vitamin E; Vitamins; Vitiligo | 2018 |
Effects of lipoic acid and n-3 long-chain polyunsaturated fatty acid on the liver ovariectomized rat model of menopause.
Topics: Animals; Antioxidants; Diet; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Glutathione Peroxidase; Lipid Peroxidation; Liver; Malondialdehyde; Menopause; Ovariectomy; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2018 |
Alpha lipoic acid protects against chlorpyrifos-induced toxicity in Wistar rats via modulating the apoptotic pathway.
Topics: Acetylcholinesterase; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catalase; Chlorpyrifos; Cholinesterase Inhibitors; Glutathione Peroxidase; Insecticides; Liver; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2018 |
Alpha lipoic acid attenuates cadmium-induced nephrotoxicity via the mitochondrial apoptotic pathways in rat.
Topics: Antioxidants; Apoptosis; Apoptosis Inducing Factor; Cadmium; Catalase; Cytochromes c; Endodeoxyribonucleases; Glutathione; Glutathione Peroxidase; Kidney; Malondialdehyde; Mitochondria; Oxidative Stress; Superoxide Dismutase; Thioctic Acid | 2018 |
Chronic co-exposure to chlorpyrifos and deltamethrin pesticides induces alterations in serum lipids and oxidative stress in Wistar rats: mitigating role of alpha-lipoic acid.
Topics: Animals; Antioxidants; Atherosclerosis; Chlorpyrifos; Cholesterol, LDL; Lipids; Male; Malondialdehyde; Nitriles; Oxidation-Reduction; Oxidative Stress; Pesticides; Pyrethrins; Rats; Rats, Wistar; Thioctic Acid; Toxicity Tests; Triglycerides | 2018 |
The protective effects of alpha lipoic acid on methotrexate induced testis injury in rats.
Topics: Animals; Antioxidants; Catalase; Epithelial Cells; Glutathione Peroxidase; Male; Malondialdehyde; Methotrexate; Oxidants; Peroxidase; Protective Agents; Rats, Wistar; Seminiferous Tubules; Spermatogenesis; Superoxide Dismutase; Testis; Testosterone; Thioctic Acid | 2018 |
Effects of Acute Ethanol Administration on Brain Oxidative Status: The Role of Acetaldehyde.
Topics: Acetaldehyde; Animals; Brain; Dipeptides; Ethanol; Glutamic Acid; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Male; Malondialdehyde; Mice; Oxidative Stress; Penicillamine; Protein Carbonylation; Thioctic Acid | 2019 |
The effect of alpha‑lipoic acid on oxidative parameters and liver injury in rats with obstructive jaundice.
Topics: Animals; Antioxidants; Bile Ducts; Glutathione; Humans; Jaundice, Obstructive; Ligation; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2019 |
Protective Effects of α-Lipoic Acid on Vascular Oxidative Stress in Rats with Hyperuricemia.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Peroxidase; Hyperuricemia; Male; Malondialdehyde; Oxidative Stress; Rats; Superoxide Dismutase; Thioctic Acid; Vascular System Injuries | 2019 |
Integrative application of licorice root extract or lipoic acid with fulvic acid improves wheat production and defenses under salt stress conditions.
Topics: Antioxidants; Benzopyrans; Glycyrrhiza; Hydrogen Peroxide; Malondialdehyde; Photosynthesis; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Salinity; Salt Stress; Soil; Thioctic Acid; Triticum | 2020 |
Potential Protective Role of Rutin and Alpha-lipoic Acid Against Cisplatin-induced Nephrotoxicity in Rats.
Topics: Albumins; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cisplatin; Creatinine; Erythrocyte Count; Hemoglobins; Inflammation; Injections, Intraperitoneal; Kidney; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Rutin; Thioctic Acid; Urea | 2019 |
α-Lipoic acid protects against microcystin-LR induced hepatotoxicity through regeneration of glutathione via activation of Nrf2.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Reductase; Hep G2 Cells; Humans; Malondialdehyde; Marine Toxins; Mice; Mice, Inbred BALB C; Microcystins; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Thioctic Acid | 2020 |
The Protective Roles of Vitamin E and α-Lipoic Acid Against Nephrotoxicity, Lipid Peroxidation, and Inflammatory Damage Induced by Gold Nanoparticles.
Topics: Animals; Biomarkers; Creatinine; Glutathione; Gold; Inflammation; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Metal Nanoparticles; Oxidative Stress; Rats, Inbred WKY; Thioctic Acid; Uric Acid; Vitamin E | 2020 |
The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats.
Topics: Alanine Transaminase; Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytokines; Glutathione; Inflammation Mediators; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Pulmonary Fibrosis; Rats; Rats, Wistar; Thioctic Acid; Vasodilator Agents | 2021 |
Lipoic Acid Combined with Melatonin Mitigates Oxidative Stress and Promotes Root Formation and Growth in Salt-Stressed Canola Seedlings (
Topics: Antioxidants; Biomass; Brassica napus; Crops, Agricultural; Homeostasis; Malondialdehyde; Melatonin; Minerals; Oxidative Stress; Phenols; Photosynthesis; Pigments, Biological; Plant Leaves; Plant Roots; Salt Stress; Thioctic Acid | 2021 |
The Neuroprotective Effect of α-Lipoic Acid and/or Metformin against the Behavioral and Neurochemical Changes Induced by Hypothyroidism in Rat.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Brain-Derived Neurotrophic Factor; Dopamine; Glutathione; Hypothyroidism; Malondialdehyde; Metformin; Neuroprotective Agents; Nitric Oxide; Norepinephrine; Propylthiouracil; Rats; Serotonin; Thioctic Acid; Tumor Necrosis Factor-alpha | 2022 |
Alpha-lipoic acid impedes myocardial ischemia-reperfusion injury, myocardial apoptosis, and oxidative stress by regulating HMGB1 expression.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cytokines; HMGB1 Protein; Inflammation; Interleukin-6; Malondialdehyde; Myocardial Reperfusion Injury; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Thioctic Acid; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Impact of Enoxaparin +α Lipoic acid combination on oxidative stress, follicle development and apoptotic damage in ovarian ischemia reperfusion model.
Topics: Animals; Antioxidants; Biomarkers; Catalase; Enoxaparin; Female; Follicle Stimulating Hormone; Glutathione Peroxidase; Ischemia; Malondialdehyde; Oxidative Stress; Progesterone; Rats; Reperfusion; Reperfusion Injury; Thioctic Acid | 2022 |