thioctic acid has been researched along with lysine in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (16.00) | 18.7374 |
| 1990's | 18 (36.00) | 18.2507 |
| 2000's | 6 (12.00) | 29.6817 |
| 2010's | 12 (24.00) | 24.3611 |
| 2020's | 6 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Hayakawa, K; Oizumi, J | 2 |
| Rodriguez-Pombo, P; Ugarte, M | 1 |
| Baltes, W; Mattulat, A | 1 |
| Coppel, RL; Gershwin, ME; Iwayama, T; Leung, PS | 1 |
| Fujiwara, K; Motokawa, Y; Okamura-Ikeda, K | 2 |
| Ali, ST; Guest, JR | 1 |
| Backman-Gullers, B; Hannestad, U; Nilsson, L; Sörbo, B | 1 |
| Creaghan, IT; Guest, JR | 1 |
| Parker, GS; Whittaker, PA | 1 |
| Guest, JR; Herbert, AA | 1 |
| Carrillo-Castañeda, G; Ortega, MV | 1 |
| Christen, U; Clarke, JB; Gandolfi, AJ; Gut, J; Kenna, JG; Quinn, J; Yeaman, SJ | 1 |
| Guest, JR; Maeda-Yorita, K; Massey, V; Russell, GC; Williams, CH | 1 |
| Handelman, G; Konishi, T; Mathur, VV; Matsugo, S; Packer, L; Tritschler, HJ | 1 |
| Garganta, CL; Wolf, B | 1 |
| Nerlich, AG; Schleicher, ED; Wagner, E | 1 |
| Bisswanger, H; Raddatz, G | 1 |
| Akiba, S; Konishi, T; Matsugo, S; Packer, L | 1 |
| Atalay, M; Hanninen, O; Khanna, S; Laaksonen, DE; Lodge, JK; Packer, L; Roy, S; Sen, CK | 1 |
| Bassendine, MF; Diamond, AG; Jones, DE; Palmer, JM; Yeaman, SJ | 1 |
| Perham, RN; Reche, P | 1 |
| Howard, MJ; Jones, DD; Perham, RN; Stott, KM | 1 |
| Baumgartner, ER; Baur, B; Suormala, T | 1 |
| Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A | 1 |
| HATAKEYAMA, T | 1 |
| REED, LJ; SUZUKI, K | 1 |
| KATO, H; KONISHI, S; KUSUNOKI, T; MIBU, A; NAKAMURA, T | 1 |
| Allina, J; Bronk, SF; Fiel, MI; Gershwin, ME; Gores, GJ; Hu, B; Huebert, RC; LaRusso, NF; Odin, JA; Sullivan, DM; Thung, SN; van de Water, J | 1 |
| Fukushima, T; Inagaki, S; Min, JZ; Satoh, S; Shindoh, M; Toyo'oka, T | 1 |
| Cottin, Y; Ghibu, S; Richard, C; Rochette, L; Vergely, C; Zeller, M | 1 |
| Dobner, B; Drescher, S; Graf, G; Hause, G; Meister, A | 1 |
| Casteel, J; Miernyk, JA; Thelen, JJ | 1 |
| Konishi, T; Matsugo, S; Motafakkerazad, R; Wada, N; Wang, MY | 1 |
| Cheng, R; Deng, C; Meng, F; Wu, L; Zhong, Z; Zou, Y | 1 |
| Coelho, JG; Dalazen, GR; Dutra-Filho, CS; Freitas, R; Jacques, CE; Mazzola, PN; Terra, M | 1 |
| Hedayati, M; Hosseinpanah, F; Nafar, M; Noori, N; Tabibi, H | 1 |
| Cheng, R; Deng, C; Meng, F; Xie, F; Zhang, J; Zhong, Y; Zhong, Z | 1 |
| Chang, CR; Chen, MH; Kao, SH; Lee, HM; Lee, WS; Lo, MC; Lu, CI | 1 |
| Ling, Y; Meng, G; Yang, Y; Zhang, S; Zhang, W; Zhu, H | 1 |
| Amenta, F; Ben, DD; Buccioni, M; Lambertucci, C; Marucci, G; Navia, AM; Ngouadjeu Ngnintedem, MA; Ricciutelli, M; Spinaci, A; Volpini, R | 1 |
| Chen, MH; Hsueh, YT; Kuo, YT; Lee, HM; Lo, MC | 1 |
| Chwatko, G; Głowacka, IE; Głowacki, R; Kamińska, A; Pasternak, B | 1 |
| Ding, Y; Ni, C; Wen, Q; Zhang, L | 1 |
| Chwatko, G; Kamińska, A | 1 |
| Berndtsson, J; Nolte, H; Ott, M; Škerlová, J; Stenmark, P | 1 |
| Boutin, JA; Ferry, G; Fould, B; Jeantet, E; Marcheteau, E; Rouch, A; Schirer, A; Stojko, J | 1 |
| Bouleau, A; Chevaleyre, C; Dubois, S; Evans, MJ; Kereselidze, D; Kuhnast, B; Nozach, H; Richard, M; Specklin, S; Tran, VL; Truillet, C | 1 |
1 review(s) available for thioctic acid and lysine
| Article | Year |
|---|---|
Antioxidant properties of an endogenous thiol: Alpha-lipoic acid, useful in the prevention of cardiovascular diseases.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Diabetic Neuropathies; Dietary Supplements; Endothelium, Vascular; Humans; Lysine; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Structure; Reactive Oxygen Species; Thioctic Acid | 2009 |
2 trial(s) available for thioctic acid and lysine
| Article | Year |
|---|---|
Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Arginine; Blood Pressure; Creatinine; Diabetic Nephropathies; Double-Blind Method; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyridoxine; Thioctic Acid | 2013 |
The first method for determination of lipoyllysine in human urine after oral lipoic acid supplementation.
Topics: Administration, Oral; Adult; Analytic Sample Preparation Methods; Dietary Supplements; Female; Healthy Volunteers; Humans; Lysine; Male; Middle Aged; Reference Standards; Thioctic Acid; Urinalysis | 2019 |
47 other study(ies) available for thioctic acid and lysine
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Release of anchored membrane enzymes by lipoamidase.
Topics: Amides; Amidohydrolases; Animals; Cell Membrane; Esters; Hydrolysis; Lysine; Membrane Proteins; Myristic Acid; Myristic Acids; Palmitic Acid; Palmitic Acids; Swine; Thioctic Acid | 1992 |
Biotin transport in primary culture of astrocytes: effect of biotin deficiency.
Topics: Animals; Astrocytes; Biological Transport; Biotin; Cells, Cultured; Lysine; Membrane Potentials; Thioctic Acid; Valinomycin | 1992 |
Determination of lipoic acid in meat of commercial quality.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Food Analysis; Gas Chromatography-Mass Spectrometry; Hydrolysis; Lysine; Meat; Sheep; Swine; Thioctic Acid | 1992 |
Site-directed mutagenesis of lysine within the immunodominant autoepitope of PDC-E2.
Topics: Autoantigens; Base Sequence; Binding Sites; DNA; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Immunoblotting; Liver Cirrhosis, Biliary; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyruvate Dehydrogenase Complex; Thioctic Acid | 1990 |
Lipoylation of H-protein of the glycine cleavage system. The effect of site-directed mutagenesis of amino acid residues around the lipoyllysine residue on the lipoate attachment.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cattle; Chickens; Glycine; Glycine Decarboxylase Complex H-Protein; Glycine Dehydrogenase (Decarboxylating); Humans; Hydrolysis; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Biosynthesis; Thioctic Acid; Transcription, Genetic | 1991 |
Isolation and characterization of lipoylated and unlipoylated domains of the E2p subunit of the pyruvate dehydrogenase complex of Escherichia coli.
Topics: Acetylation; Acetyltransferases; Amino Acid Sequence; Ammonium Sulfate; Dihydrolipoyllysine-Residue Acetyltransferase; Escherichia coli; Gene Expression; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Point; Lysine; Molecular Sequence Data; Mutation; Plasmids; Protein Conformation; Pyruvate Dehydrogenase Complex; Thioctic Acid; Transformation, Bacterial; Trypsin | 1990 |
Studies on lipoamidase: characterization of the enzyme in human serum and breast milk.
Topics: 4-Aminobenzoic Acid; Amidohydrolases; Edetic Acid; Enzyme Activation; Female; Humans; Hydrogen-Ion Concentration; Lysine; Male; Milk, Human; para-Aminobenzoates; Protease Inhibitors; Reference Values; Substrate Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents; Thioctic Acid | 1990 |
Determination of lipoyllysine derived from enzymes by liquid chromatography.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Hydrolysis; Lysine; Myocardium; Pyruvate Dehydrogenase Complex; Thioctic Acid | 1989 |
Gene-protein relationships of the alpha-keto acid dehydrogenase complexes of Escherichia coli K12: isolation and characterization of lipoamide dehydrogenase mutants.
Topics: Acetates; Cell-Free System; Dihydrolipoamide Dehydrogenase; Escherichia coli; Genes; Genetic Complementation Test; Glucose; Ketoglutaric Acids; Ligases; Lysine; Methionine; Multienzyme Complexes; Mutation; Oxidoreductases; Pyruvate Dehydrogenase Complex; Spectrophotometry; Succinate Dehydrogenase; Succinates; Thioctic Acid; Transduction, Genetic | 1973 |
A mutant strain of Escherichia coli requiring lipoic acid for normal growth.
Topics: Amino Acids; Escherichia coli; Glutamates; Glutarates; Isoleucine; Lysine; Methionine; Mutation; Proline; Succinates; Thioctic Acid; Ultraviolet Rays | 1968 |
Biochemical and genetic studies with lysine+methionine mutants of Escherichia coli: lipoic acid and alpha-ketoglutarate dehydrogenase-less mutants.
Topics: Acetates; Bacteriophage Typing; Chromosomes, Bacterial; Conjugation, Genetic; Escherichia coli; Genetics, Microbial; Lysine; Methionine; Mutation; Oxidoreductases; Succinates; Thioctic Acid; Transduction, Genetic | 1968 |
Mutants of Salmonella typhimurium lacking phosphoenolpyruvate carboxykinase and alpha-ketoglutarate dehydrogenase activities.
Topics: Alcohol Oxidoreductases; Benzoates; Carbon Isotopes; Cell-Free System; Chromosome Mapping; Chromosomes, Bacterial; Colorimetry; Conjugation, Genetic; Culture Media; Lysine; Methionine; Mutation; Nicotinic Acids; Oxygen; Pyruvate Kinase; Salmonella Phages; Salmonella typhimurium; Spectrophotometry; Succinates; Thioctic Acid; Transduction, Genetic | 1970 |
Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid.
Topics: Acetyltransferases; Amino Acid Sequence; Autoantigens; Autoimmune Diseases; Binding, Competitive; Chemical and Drug Induced Liver Injury; Dihydrolipoyllysine-Residue Acetyltransferase; Epitopes; Halothane; Humans; Immunoblotting; Liver; Lysine; Models, Molecular; Molecular Sequence Data; Oligopeptides; Pyruvate Dehydrogenase Complex; Thioctic Acid | 1994 |
Modulation of the oxidation-reduction potential of the flavin in lipoamide dehydrogenase from Escherichia coli by alteration of a nearby charged residue, K53R.
Topics: Circular Dichroism; Dihydrolipoamide Dehydrogenase; Electrochemistry; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Lysine; NAD; Oxidation-Reduction; Photochemistry; Spectrometry, Fluorescence; Spectrophotometry; Thioctic Acid | 1994 |
Lipoylation of acyltransferase components of alpha-ketoacid dehydrogenase complexes.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acyltransferases; Animals; Base Sequence; Cattle; Cloning, Molecular; Conserved Sequence; DNA, Complementary; Glutamic Acid; Glycine; Ketone Oxidoreductases; Lysine; Mitochondria, Liver; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Thioctic Acid | 1996 |
Amplified determination of lipoyl groups by lipoamide dehydrogenase in the presence of oxidized glutathione.
Topics: Dihydrolipoamide Dehydrogenase; Disulfides; Glutathione; Glutathione Disulfide; Kinetics; Lysine; NAD; Oxidation-Reduction; Substrate Specificity; Thioctic Acid | 1996 |
A colorimetric assay of lipoyl-N-epsilon-lysine hydrolysis activity using 2,6-dibromoquinone-4-chlorimide.
Topics: 4-Aminobenzoic Acid; Amidohydrolases; Animals; Biotinidase; Colorimetry; Humans; Hydrolysis; In Vitro Techniques; Indicators and Reagents; Liver; Lymphocytes; Lysine; Quinones; Rats; Thioctic Acid | 1996 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E | 1997 |
Receptor site and stereospecifity of dihydrolipoamide dehydrogenase for R- and S-lipoamide: a molecular modeling study.
Topics: Amino Acid Sequence; Animals; Azotobacter vinelandii; Binding Sites; Biotechnology; Dihydrolipoamide Dehydrogenase; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Species Specificity; Stereoisomerism; Substrate Specificity; Thermodynamics; Thioctic Acid | 1997 |
Assay of protein-bound lipoic acid in tissues by a new enzymatic method.
Topics: Animals; Cattle; Dihydrolipoamide Dehydrogenase; Glutathione Disulfide; Lysine; NAD; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Rats; Thioctic Acid | 1998 |
Skeletal muscle and liver lipoyllysine content in response to exercise, training and dietary alpha-lipoic acid supplementation.
Topics: Animals; Dietary Supplements; Liver; Lysine; Male; Muscle, Skeletal; Physical Conditioning, Animal; Rats; Rats, Wistar; Thioctic Acid | 1998 |
T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC).
Topics: Autoantigens; Autoimmunity; Dihydrolipoyllysine-Residue Acetyltransferase; Epitopes; Humans; Immunodominant Epitopes; Liver Cirrhosis, Biliary; Lysine; Peptide Fragments; Pyruvate Dehydrogenase Complex; Recombinant Proteins; T-Lymphocytes; Thioctic Acid | 1999 |
Structure and selectivity in post-translational modification: attaching the biotinyl-lysine and lipoyl-lysine swinging arms in multifunctional enzymes.
Topics: Acetyl-CoA Carboxylase; Amino Acid Sequence; Base Sequence; Biotinylation; Escherichia coli; Ligases; Lysine; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Insertional; Mutation; Protein Processing, Post-Translational; Protein Structure, Secondary; Sequence Alignment; Substrate Specificity; Thioctic Acid | 1999 |
Restricted motion of the lipoyl-lysine swinging arm in the pyruvate dehydrogenase complex of Escherichia coli.
Topics: Acylation; Escherichia coli; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Protein Structure, Tertiary; Pyruvate Dehydrogenase Complex; Thermodynamics; Thioctic Acid | 2000 |
Biocytin and biotin uptake into NB2a neuroblastoma and C6 astrocytoma cells.
Topics: Animals; Astrocytoma; Binding, Competitive; Biological Transport; Biotin; Carbon-Carbon Ligases; Cell Line, Transformed; Choline; Dose-Response Relationship, Drug; Enzyme Activation; Lysine; Mice; Neuroblastoma; Neuroglia; Neurons; Potassium; Rats; Sodium; Thioctic Acid | 2002 |
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates | 2003 |
[Studies on nutrition and hepatic injury. 4. Studies on experimental fatty liver; effects of addition of lipoic acid, orotic acid, lvsine, threonine, and fermented sovbeans].
Topics: Fatty Liver; Glycine max; Liver Diseases; Lysine; Nutritional Status; Orotic Acid; Thioctic Acid; Threonine | 1961 |
LIPOAMIDASE.
Topics: Amidohydrolases; Chromatography; Enterococcus faecalis; Escherichia coli; Lysine; Pyruvates; Research; Thioctic Acid | 1963 |
STUDIES ON THE METABOLISM OF ALPHA-LIPOIC ACID IN CHILDHOOD. 3. EFFECT OF DIETARY COMPOSITION AND ANBOLIC STEROID.
Topics: Amino Acids; Anabolic Agents; Biological Assay; Child; Deficiency Diseases; Diet; Dietary Proteins; Enterococcus faecalis; Fluids and Secretions; Kidney; Liver; Lysine; Metabolism; Rats; Steroids; Thioctic Acid; Tryptophan; Urine | 1965 |
T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis.
Topics: Animals; Apoptosis; Autoantigens; Cathepsin B; Dihydrolipoyllysine-Residue Acetyltransferase; Epithelial Cells; Female; Glutathione; HeLa Cells; Humans; Liver Cirrhosis, Biliary; Lysine; Mice; Oxidation-Reduction; Peptide Hydrolases; Phagocytosis; Rats; T-Lymphocytes; Thioctic Acid | 2006 |
Selective and sensitive determination of lipoyllysine (protein-bound alpha-lipoic acid) in biological specimens by high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorescence; Fluorescent Dyes; Lysine; Male; Mass Spectrometry; Mice; Proteins; Rats; Sensitivity and Specificity; Staining and Labeling; Thioctic Acid; Time Factors | 2008 |
Amino-functionalized single-chain bolalipids: synthesis and aggregation behavior of new basic building blocks.
Topics: Amines; Calorimetry, Differential Scanning; Carboxylic Acids; Hydrogels; Lipids; Lysine; Micelles; Microscopy, Electron, Transmission; Molecular Structure; Nanofibers; Phase Transition; Sorbic Acid; Thioctic Acid | 2010 |
Mapping the lipoylation site of Arabidopsis thaliana plastidial dihydrolipoamide S-acetyltransferase using mass spectrometry and site-directed mutagenesis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Catalytic Domain; Chloroplast Proteins; Cloning, Molecular; Computational Biology; Dihydrolipoyllysine-Residue Acetyltransferase; Escherichia coli; Lipoylation; Lysine; Metagenomics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Phylogeny; Protein Structure, Secondary; Pyruvate Dehydrogenase Complex; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioctic Acid | 2011 |
Simple HPLC evaluation of lipoamidase activity in tissue using a newly synthesized fluorescent substrate, dansyl-α-lipoyllysine.
Topics: Amidohydrolases; Animals; Chromatography, High Pressure Liquid; Dansyl Compounds; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Limit of Detection; Lysine; Male; Organ Specificity; Rats; Rats, Wistar; Spectrometry, Fluorescence; Spleen; Stereoisomerism; Substrate Specificity; Thioctic Acid | 2011 |
Intracellular release of doxorubicin from core-crosslinked polypeptide micelles triggered by both pH and reduction conditions.
Topics: Antineoplastic Agents; Colloids; Cross-Linking Reagents; Cyclohexanecarboxylic Acids; Dicarboxylic Acids; Doxorubicin; HeLa Cells; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Hydrolysis; Intracellular Space; Lysine; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Electron, Transmission; Oxidation-Reduction; Particle Size; Peptides; Polyethylene Glycols; Thioctic Acid | 2013 |
Pipecolic acid induces oxidative stress in vitro in cerebral cortex of young rats and the protective role of lipoic acid.
Topics: Animals; Antioxidants; Catalase; Cerebral Cortex; Female; Glutathione; In Vitro Techniques; Lipid Peroxidation; Lysine; Male; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; Pipecolic Acids; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2014 |
Reversibly crosslinked hyaluronic acid nanoparticles for active targeting and intelligent delivery of doxorubicin to drug resistant CD44+ human breast tumor xenografts.
Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Chemistry, Pharmaceutical; Cross-Linking Reagents; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Hyaluronan Receptors; Hyaluronic Acid; Injections, Intravenous; Lysine; MCF-7 Cells; Mice, Nude; Molecular Targeted Therapy; Nanomedicine; Nanoparticles; Solubility; Technology, Pharmaceutical; Thioctic Acid; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells.
Topics: Animals; Antioxidants; Biomarkers; Cell Line, Tumor; Diabetes Mellitus; Dietary Supplements; Down-Regulation; Glycation End Products, Advanced; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lysine; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondrial Dynamics; Mitophagy; Oxidants; Phagosomes; Rats; Receptor for Advanced Glycation End Products; Serum Albumin, Bovine; Thioctic Acid | 2015 |
pH-responsive hybrid quantum dots for targeting hypoxic tumor siRNA delivery.
Topics: Animals; Cadmium Compounds; Cell Hypoxia; Cell Survival; Deoxyglucose; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Glucose Transporter Type 1; Hep G2 Cells; Humans; Hydrazones; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Lysine; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Oxygen; Peptides; Polyethylene Glycols; Quantum Dots; RNA, Small Interfering; RNAi Therapeutics; Tellurium; Thioctic Acid; Time Factors; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2015 |
Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA.
Topics: Animals; In Vitro Techniques; Intestinal Absorption; Lysine; Male; Permeability; Rats, Wistar; Thioctic Acid | 2018 |
Alpha-lipoic acid suppresses N
Topics: Cells, Cultured; Epithelial-Mesenchymal Transition; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Tubules, Proximal; Lysine; Reactive Oxygen Species; Thioctic Acid | 2018 |
Synthesis of core-crosslinked zwitterionic polymer nano aggregates and pH/Redox responsiveness in drug controlled release.
Topics: Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Carriers; Drug Liberation; HeLa Cells; Humans; Hydrogen-Ion Concentration; Ions; Lysine; Nanostructures; Oxidation-Reduction; Particle Size; Polyethylene Glycols; Polymers; Thioctic Acid | 2020 |
Estimation of Lipoyllysine Content in Meat and Its Antioxidative Capacity.
Topics: Animals; Antioxidants; Cattle; Chickens; Chromatography, High Pressure Liquid; Hydrolysis; Lysine; Meat; Mice; Rats; Thioctic Acid | 2020 |
Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion.
Topics: Catalytic Domain; Cryoelectron Microscopy; Dihydrolipoyllysine-Residue Acetyltransferase; Escherichia coli Proteins; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Protein Domains; Pyruvate Dehydrogenase Complex; Thioctic Acid | 2021 |
Further assessments of ligase LplA-mediated modifications of proteins in vitro and in cellulo.
Topics: Click Chemistry; Escherichia coli; Escherichia coli Proteins; HEK293 Cells; Humans; Ligases; Lysine; Protein Engineering; Protein Processing, Post-Translational; Thioctic Acid; Thioredoxins | 2022 |
Impact of Radiolabeling Strategies on the Pharmacokinetics and Distribution of an Anti-PD-L1 PET Ligand.
Topics: Amides; Animals; B7-H1 Antigen; Cell Line, Tumor; Fluorine Radioisotopes; Immunoglobulin Fragments; Ligands; Ligases; Lysine; Mice; Neoplasms; Peptides; Positron-Emission Tomography; Radiopharmaceuticals; Thioctic Acid; Tissue Distribution | 2022 |