thioctic acid and glutathione disulfide

thioctic acid has been researched along with glutathione disulfide in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's8 (30.77)18.2507
2000's9 (34.62)29.6817
2010's8 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bast, A; Haenen, GR2
Bustamante, J; Orrenius, S; Slater, AF1
Assadnazari, H; Haramaki, N; Packer, L; Schepkin, V; Zimmer, G1
Maitra, I; Packer, L; Serbinova, E; Tritschler, HJ1
Handelman, G; Konishi, T; Mathur, VV; Matsugo, S; Packer, L; Tritschler, HJ1
Casley, WL; Moon, TW; Otto, DM; Sen, CK1
Akiba, S; Konishi, T; Matsugo, S; Packer, L1
Cooper, K; Ercal, N; Gurer, H; Kellogg, G; Neal, R1
Fathallah, L; Greene, DA; Obrosova, IG1
Cao, X; Greene, DA; Obrosova, I; Stevens, MJ; Van Huysen, C1
Arivazhagan, P; Panneerselvam, C; Ramanathan, K1
Husain, K; Rybak, LP; Somani, SM; Whitworth, C1
Ames, BN; Liu, J; Miller, SS; Suh, JH; Voloboueva, LA1
Jin, SM; Kim, SR; Lee, KS; Lee, KY; Lee, YC; Min, KH; Park, SJ; Yoo, WH1
Dai, A; Palaniappan, AR1
Ahmed, KM; Hai, CX; Li, JJ; Liu, R; Nantajit, D; Rosenthal, FS1
Golder, C; Hagen, TM; Joisher, N; Joshi, DK; Miller, EP; Zicker, SC1
Ishii, T; Mori, T; Nakayama, T; Wakabayashi, M1
Atalay, M; Khanna, S; Laaksonen, DE; Lappalainen, J; Lappalainen, Z; Oksala, KJ; Sen, CK1
Seybolt, SE1
Karayakar, F; Karaytug, S; Sevgiler, Y1
Connell, BJ; Khan, BV; Rajagopal, D; Saleh, MC; Saleh, TM1
Arambašić, J; Dinić, S; Grdović, N; Karadžić, B; Marković, J; Mihailović, M; Poznanović, G; Uskoković, A; Vidaković, M1
Jiang, F; Qin, L; Xing, ZG; Yu, GD; Zhao, WH1
Aragón, CG; Baliño, P; Muriach, M; Romero-Cano, R; Sánchez-Andrés, JV; Valls, V1

Trials

1 trial(s) available for thioctic acid and glutathione disulfide

ArticleYear
Safety of long-term feeding of dl-alpha-lipoic acid and its effect on reduced glutathione:oxidized glutathione ratios in beagles.
    Veterinary therapeutics : research in applied veterinary medicine, 2002,Summer, Volume: 3, Issue:2

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dogs; Female; Glutathione; Glutathione Disulfide; Male; Thioctic Acid

2002

Other Studies

25 other study(ies) available for thioctic acid and glutathione disulfide

ArticleYear
Scavenging of hypochlorous acid by lipoic acid.
    Biochemical pharmacology, 1991, Nov-06, Volume: 42, Issue:11

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Enzyme Activation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypochlorous Acid; Kinetics; Oxidation-Reduction; Pancreatic Elastase; Thioctic Acid

1991
Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation.
    Biochimica et biophysica acta, 1988, Dec-16, Volume: 963, Issue:3

    Topics: Animals; Free Radicals; Glutathione; Glutathione Disulfide; Lipid Peroxides; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Thioctic Acid; Vitamin E

1988
Antioxidant inhibition of thymocyte apoptosis by dihydrolipoic acid.
    Free radical biology & medicine, 1995, Volume: 19, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Chromatin; Etoposide; Glutathione; Glutathione Disulfide; Male; Methylprednisolone; Microscopy, Confocal; Rats; Rats, Sprague-Dawley; Thioctic Acid; Thymus Gland

1995
The influence of vitamin E and dihydrolipoic acid on cardiac energy and glutathione status under hypoxia-reoxygenation.
    Biochemistry and molecular biology international, 1995, Volume: 37, Issue:3

    Topics: Animals; Antioxidants; Energy Metabolism; Glutathione; Glutathione Disulfide; Heart; Hypoxia; Male; Myocardial Reperfusion; Myocardium; Oxidative Stress; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Thioctic Acid; Vitamin E

1995
Stereospecific effects of R-lipoic acid on buthionine sulfoximine-induced cataract formation in newborn rats.
    Biochemical and biophysical research communications, 1996, Apr-16, Volume: 221, Issue:2

    Topics: Animals; Animals, Newborn; Ascorbic Acid; Buthionine Sulfoximine; Cataract; Female; Glutathione; Glutathione Disulfide; Lens, Crystalline; Methionine Sulfoximine; Pregnancy; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thioctic Acid; Vitamin E

1996
Amplified determination of lipoyl groups by lipoamide dehydrogenase in the presence of oxidized glutathione.
    Biochemistry and molecular biology international, 1996, Volume: 38, Issue:6

    Topics: Dihydrolipoamide Dehydrogenase; Disulfides; Glutathione; Glutathione Disulfide; Kinetics; Lysine; NAD; Oxidation-Reduction; Substrate Specificity; Thioctic Acid

1996
Regulation of 3,3',4,4'-tetrachlorobiphenyl induced cytochrome P450 metabolism by thiols in tissues of rainbow trout.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 117, Issue:3

    Topics: Analysis of Variance; Animals; Blotting, Western; Buthionine Sulfoximine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Oncorhynchus mykiss; Oxidation-Reduction; Polychlorinated Biphenyls; RNA, Messenger; Thioctic Acid

1997
Assay of protein-bound lipoic acid in tissues by a new enzymatic method.
    Analytical biochemistry, 1998, May-01, Volume: 258, Issue:2

    Topics: Animals; Cattle; Dihydrolipoamide Dehydrogenase; Glutathione Disulfide; Lysine; NAD; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Rats; Thioctic Acid

1998
Effects of some sulfur-containing antioxidants on lead-exposed lenses.
    Free radical biology & medicine, 1999, Volume: 26, Issue:1-2

    Topics: Animals; Antioxidants; Captopril; Cysteine; Glutathione; Glutathione Disulfide; Lead; Lens, Crystalline; Lipid Peroxides; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species; Sulfur; Taurine; Thioctic Acid

1999
Early changes in lipid peroxidation and antioxidative defense in diabetic rat retina: effect of DL-alpha-lipoic acid.
    European journal of pharmacology, 2000, Jun-09, Volume: 398, Issue:1

    Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Male; Rats; Rats, Wistar; Retina; Superoxide Dismutase; Thioctic Acid

2000
Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.
    Diabetes, 2000, Volume: 49, Issue:6

    Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Energy Metabolism; Enzymes; Glutathione; Glutathione Disulfide; Male; Neural Conduction; Oxidative Stress; Peripheral Nerves; Rats; Rats, Wistar; Regional Blood Flow; Sodium-Potassium-Exchanging ATPase; Thioctic Acid

2000
Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats.
    Chemico-biological interactions, 2001, Nov-28, Volume: 138, Issue:2

    Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Injections, Intraperitoneal; Kidney; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Oxidoreductases; Rats; Rats, Wistar; Thioctic Acid; Vitamin E

2001
Partial protection by lipoic acid against carboplantin-induced ototoxicity in rats.
    Biomedical and environmental sciences : BES, 2005, Volume: 18, Issue:3

    Topics: Animals; Antioxidants; Auditory Threshold; Carboplatin; Catalase; Cochlea; Evoked Potentials, Auditory, Brain Stem; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hearing Loss, Sensorineural; Lipid Peroxidation; Male; Malondialdehyde; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid

2005
(R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:11

    Topics: Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cytoprotection; Fluorescent Dyes; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Humans; Oxidative Stress; Pigment Epithelium of Eye; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; tert-Butylhydroperoxide; Thioctic Acid; Up-Regulation

2005
Antioxidant down-regulates interleukin-18 expression in asthma.
    Molecular pharmacology, 2006, Volume: 70, Issue:4

    Topics: Animals; Antioxidants; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Down-Regulation; Female; Glutathione; Glutathione Disulfide; Immunoglobulin E; Interleukin-18; Interleukins; Lung; Mice; Mice, Inbred C57BL; Ovalbumin; Reactive Oxygen Species; RNA, Messenger; Thioctic Acid; Transcription Factor RelA

2006
Mitochondrial ageing and the beneficial role of alpha-lipoic acid.
    Neurochemical research, 2007, Volume: 32, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Triphosphate; Aging; Animals; Citric Acid Cycle; Deoxyguanosine; Electron Transport; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Male; Mitochondria; Rats; Rats, Wistar; Thioctic Acid

2007
Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats.
    International journal of molecular medicine, 2007, Volume: 19, Issue:6

    Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Gene Expression Profiling; Glutathione; Glutathione Disulfide; Hydroxyproline; Lung; Male; Matrix Metalloproteinase 1; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tissue Inhibitor of Metalloproteinase-1

2007
A new method for the detection and characterization of alpha-lipoic acid mixed disulphides.
    Free radical research, 2010, Volume: 44, Issue:4

    Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Glutathione; Glutathione Disulfide; Iodoacetamide; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds; Tandem Mass Spectrometry; Thioctic Acid

2010
Acute exercise and thioredoxin-1 in rat brain, and alpha-lipoic acid and thioredoxin-interacting protein response, in diabetes.
    International journal of sport nutrition and exercise metabolism, 2010, Volume: 20, Issue:3

    Topics: Animals; Antioxidants; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Male; Oxidation-Reduction; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Thioredoxins

2010
Is it time to reassess alpha lipoic acid and niacinamide therapy in schizophrenia?
    Medical hypotheses, 2010, Volume: 75, Issue:6

    Topics: Antioxidants; Dopamine; Glutathione; Glutathione Disulfide; Humans; Mitochondria; Mitochondrial Membranes; Niacinamide; Schizophrenia; Thioctic Acid

2010
Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.
    Arhiv za higijenu rada i toksikologiju, 2011, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Curcumin; Enzyme Inhibitors; Free Radical Scavengers; Glutathione Disulfide; Glutathione Peroxidase; Lipid Peroxidation; Muscle, Skeletal; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid

2011
UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Volume: 302, Issue:7

    Topics: Acetophenones; Animals; Biomarkers; Disease Models, Animal; Glutathione Disulfide; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Mitochondria; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Superoxide Dismutase; Thioctic Acid

2012
Decreased O-GlcNAcylation of the key proteins in kinase and redox signalling pathways is a novel mechanism of the beneficial effect of α-lipoic acid in diabetic liver.
    The British journal of nutrition, 2013, Aug-28, Volume: 110, Issue:3

    Topics: Aminoacylation; Animals; Antioxidants; Catalase; CCAAT-Binding Factor; Diabetes Mellitus, Experimental; DNA Damage; Glutathione; Glutathione Disulfide; Liver; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Thioctic Acid; Transaminases; Transcription, Genetic

2013
Effects and mechanism of lipoic acid on beta-amyloid-intoxicated C6 glioma cells.
    Genetics and molecular research : GMR, 2015, Oct-30, Volume: 14, Issue:4

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cell Line, Tumor; Cell Proliferation; Gene Expression; Glioma; Glutathione; Glutathione Disulfide; Mitochondria; Oxidation-Reduction; Rats; RNA, Messenger; Superoxide Dismutase; Thioctic Acid

2015
Effects of Acute Ethanol Administration on Brain Oxidative Status: The Role of Acetaldehyde.
    Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:8

    Topics: Acetaldehyde; Animals; Brain; Dipeptides; Ethanol; Glutamic Acid; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Male; Malondialdehyde; Mice; Oxidative Stress; Penicillamine; Protein Carbonylation; Thioctic Acid

2019