thioctic acid has been researched along with acetylcysteine in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.85) | 18.7374 |
| 1990's | 15 (13.89) | 18.2507 |
| 2000's | 45 (41.67) | 29.6817 |
| 2010's | 39 (36.11) | 24.3611 |
| 2020's | 7 (6.48) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| De Graaf-Hess, AC; De Kok, A; Grande, HJ; Scouten, WH; Veeger, C; Visser, AJ | 1 |
| Burkart, V; Kallmann, B; Kolb, H; Kolb-Bachofen, V; Kröncke, KD | 1 |
| Aggarwal, BB; Packer, L; Suzuki, YJ | 1 |
| Bast, A; Haenen, GR | 1 |
| Litovitz, TL | 1 |
| Davies, MJ; Puppo, A | 1 |
| Furuishi, K; Kino, M; Misumi, S; Miyazaki, T; Shoji, S; Yamataka, K | 1 |
| Bisby, RH; Johnson, SA; Parker, AW | 1 |
| Baba, M; Kira, T; Matsuyama, M; Merin, JP; Okamoto, T | 1 |
| Han, D; Packer, L; Roy, S; Sen, CK | 1 |
| Han, D; Kobayashi, MS; Packer, L; Roy, S; Sen, CK; Tritschler, HJ | 1 |
| Cillard, J; Iwasaki, K; Kitazawa, M; Lodge, JK; McLaughlin, L; Okamoto, T; Packer, L; Saliou, C; Tetsuka, T; Yang, JP | 1 |
| Anand, R; Fernando, B; Goodier, D; Harry, D; Holt, S; Marley, R; Moore, K | 1 |
| de Champlain, J; Wu, L | 1 |
| Killoran, PL; Walleczek, J | 1 |
| Floyd, RA; Graham, KL; Kotake, Y; Tabatabaie, T; Vasquez, AM | 1 |
| Macciò, A; Mantovani, G; Massa, E; Melis, G; Mudu, MC; Mura, L | 1 |
| Packer, L; Sen, CK | 1 |
| Patrick, L | 1 |
| Courteau, J; Kocsis-Bédard, S; Niyonsenga, T; Paquette, B; Thibodeau, PA | 1 |
| Lands, L | 1 |
| Buse, MG; Greene, EL; Nelson, BA; Robinson, KA | 1 |
| Gahlinger, M | 1 |
| Freudenthaler, SM; Gleiter, CH; Pilz, J; Schreeb, KH; Wiese, A | 1 |
| Andersson, A; Hultberg, B; Isaksson, A | 1 |
| Moison, RM; Podda, E; Rijnkels, JM; van Henegouwen, GM | 1 |
| Gasic-Milenkovic, J; Loske, C; Münch, G | 1 |
| Banks, WA; Butterfield, DA; Dogrukol-Ak, D; Drake, J; Eyerman, E; Farr, SA; Morley, JE; Poon, HF | 1 |
| Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A | 1 |
| Beebe, SJ; Hargrave, BY; Lattanzio, FA; Tiangco, DA | 1 |
| Ciofani, G; Cuccurullo, F; Giamberardino, MA; Lapenna, D; Pierdomenico, SD | 1 |
| Roth, E; Spittler, A; Strasser, EM; Wessner, B | 1 |
| Atmaca, G | 1 |
| Cataldi, TR; Nardiello, D | 1 |
| Beck, CN; Fitzgibbon, WR; Gelasco, AK; Morinelli, TA; Ullian, ME | 1 |
| Hultberg, B; Hultberg, M | 2 |
| Becker, K; Fechner, A; Funk, M; Gromer, S; Gross, HJ; Grünert, A; Pons-Kühnemann, J; Schirmer, RH | 1 |
| Aimo, L; Erlejman, AG; Keen, CL; Mackenzie, GG; Oteiza, PI; Zago, MP | 1 |
| Chang, CP; Huang, WT; Lin, MT | 1 |
| Donahue, JJ; Guan, J; Kennedy, AR; Wan, XS; Ware, JH; Zhou, Z | 1 |
| Bowden, GT; Chen, QM; Sun, H; Tu, VC | 1 |
| Columbano, A; Deidda, M; Diana, A; Ledda-Columbano, GM; Pibiri, M; Sanna, L; Simbula, G | 1 |
| Aerry, R; Coleman, MD; Khan, NB; Lambert, PA; Rathbone, DL; Wanogho, E | 1 |
| Agarwal, V; Diwakar, L; Iyengar, S; Karunakaran, S; Ramakrishnan, S; Ravindranath, V; Saeed, U | 1 |
| Aal, FA; Fattah, Lel-S; Hassan, NY; Taha, EA | 1 |
| Flora, G; Flora, SJ; Mishra, M; Saxena, G | 1 |
| Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC | 1 |
| Bellosta, S; Bogani, P; Canavesi, M; Hagen, TM; Visioli, F | 1 |
| Harris, PL; Moreira, PI; Oliveira, CR; Perry, G; Santos, MS; Smith, MA; Zhu, X | 1 |
| Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N | 1 |
| Szygula, Z; Szyszka, K; Zembron-Lacny, A | 1 |
| Aytekin, M; Caylak, E; Halifeoglu, I | 1 |
| Bagh, MB; Chakrabarti, S; Maiti, AK; Roy, A | 1 |
| Güven, A; Korkmaz, A; Kul, M; Ongürü, O; Oter, S; Sarici, U; Topal, T; Tunc, T | 1 |
| Gamaliĭ, IA; Kirpichnikova, KM; Smagina, LV; Voronkina, IV | 1 |
| Slowinska-Lisowska, M; Szygula, Z; Szyszka, K; Witkowski, K; Zembron-Lacny, A | 1 |
| Filatova, NA; Gamaleĭ, IA; Kirpichnikova, KM; Vakhromova, EA | 1 |
| Ostapiuk, J; Szyszka, K; Zembron-Lacny, A | 1 |
| Aksenov, ND; Gamaleĭ, IA; Kirpichnikova, KM; Polozov, IuS; Vakhromova, EA | 1 |
| Amato, L; Bernardini, G; Braconi, D; Cavallo, G; Laschi, M; Marcolongo, R; Millucci, L; Santucci, A; Spreafico, A | 1 |
| Green, KN; Hendrix, C; LaFerla, FM; Parachikova, A | 1 |
| Karayakar, F; Karaytug, S; Sevgiler, Y | 2 |
| Aksenov, ND; Filatova, NA; Gamaleĭ, IA; Kirpichnikova, KM; Vakhromova, EA | 1 |
| Firuzi, O; Miri, R; Saso, L; Tavakkoli, M | 1 |
| Abdalla, AM; Abdelwahab, SA; Mahmoud, AM; Mahmoud, ME; Morsy, MA | 1 |
| Beseler, C; Cavalieri, EL; Rogan, E; Saeed, M; Yang, L; Zahid, M | 1 |
| Gao, S; Kim, JS; Kim, SH; Park, WH; Shah, A; Yuan, K | 1 |
| Chung, TY; Hyon, JY; Koh, JW; Shin, YJ; Wee, WR; Yi, K | 1 |
| Al-Mulla, F; Bitar, MS; Feng, J; Park, S; Yeung, KC | 1 |
| Ding, Z; Li, C; Li, R; Liu, L; Ma, R; Ma, Y; Wang, X; Yao, Y; Zhang, X | 1 |
| Barbot, J; Carvalho, F; Fernandes, AP; Gonçalves, C; Ponte, F; Porto, B; Sousa, R | 1 |
| Chakrabarti, S; Chattopadhyay, M; Ghosh, A; Thakurta, IG | 1 |
| Jiang, R; Lu, H; Peng, X; Wan, J; Xie, J; Zhang, L | 1 |
| Bou-Moughlabey, Y; Echtay, K; El-Rifai, O; Griffiths, D; Hachem, Y; Makki, RF; Nakkash-Chmaisse, H; Usta, J | 1 |
| Andreu, AL; Bianchi, P; Ferrer, I; Fourcade, S; Galino, J; López-Erauskin, J; Muñoz-Pinedo, C; Pujol, A | 1 |
| El-Desoky, KI; El-Sisi, Ael-D; El-Syaad, ME; Moussa, EA | 1 |
| Airey, C; Colosimo, M; Linnane, AW; Masci, PP; Schloss, JM; Vitetta, L | 1 |
| Amato, L; Bernardini, G; Braconi, D; Chellini, F; Collodel, G; Frediani, B; Geminiani, M; Ghezzi, L; Millucci, L; Moretti, E; Santucci, A; Spreafico, A | 1 |
| Bagh, MB; Banerjee, P; Chakrabarti, S; Chattopadhyay, S; Ghosh, A; Sahoo, A; Thakurta, IG | 1 |
| Fu, J; Ji, K; Li, G; Luan, T; Zang, B; Zhao, Y | 1 |
| Bandyopadhyay, D; Chakraborty, P; Chakravarty, B; Chattopadhyay, R; Dutta, A; Firdaus, SB; Jana, K; Manna, I | 1 |
| Cao, K; Jiang, S; Li, C; Li, Y; Liu, L; Wu, J; Zhang, X; Zhu, W | 1 |
| Arroll, MA; Neil, J; Wilder, L | 1 |
| Gamaleĭ, IA; Kirpichnikova, KM; Liublinskaia, OG | 1 |
| Brandi, ML; Fontani, F; Iantomasi, T; Marcucci, G; Vincenzini, MT | 1 |
| Bayer, SB; Hampton, MB; Winterbourn, CC | 1 |
| Greene, AF; Herrick, JR; Krisher, RL; Schoolcraft, WB; Silva, E; Strauss, K | 1 |
| Agostinis, C; Bulla, R; De Leo, R; De Seta, F; Zauli, G; Zorzet, S | 1 |
| Arús, BA; Bellaver, B; Bellaver, G; Bobermin, LD; Gonçalves, CA; Quincozes-Santos, A; Santos, CL; Souza, DG; Souza, DO | 1 |
| Banerjee, A; Bhowmick, P; Bir, A; Chakrabarti, S; Sinha, M | 1 |
| Filatova, NA; Gamaley, IA; Kirpichnikova, KM; Petrov, YP | 1 |
| Gardner, DK; Soh, YM; Truong, TT | 1 |
| Barfett, J; Jaffer, H; Mikulis, D; Murphy, K; Velauthapillai, N | 1 |
| Ajith, TA; Antonawich, F; Janardhanan, KK; Veena, RK | 1 |
| Gardner, DK; Truong, T | 1 |
| Carmona, F; de la Viuda, E; Lete, I; Mendoza, N | 1 |
| Agnes, JP; Delgobo, M; Dos Santos, VW; Gonçalves, RM; Parisotto, EB; Zamoner, A; Zanotto-Filho, A | 1 |
| Ali, S; Liao, LS; Lim, J; Luderer, U; Nguyen, ES; Ortiz, L; Reshel, S | 1 |
| Gardner, DK; Kuramoto, T; Mitzumoto, S; Montag, M; Tanaka, M; Yoshida, A | 1 |
| Gryciuk, ME; Maciejczyk, M; Mil, KM; Pawlukianiec, C; Zalewska, A; Żendzian-Piotrowska, M; Ładny, JR | 1 |
| Chabowski, A; Kasacka, I; Wołosowicz, M; Łukaszuk, B | 1 |
| Chabowski, A; Dajnowicz-Brzezik, P; Kasacka, I; Maciejczyk, M; Wołosowicz, M; Zalewska, A; Żebrowska, E; Łukaszuk, B | 1 |
| Asa, E; Jannatifar, R; Piroozmanesh, H; Sahraei, SS; Verdi, A | 1 |
11 review(s) available for thioctic acid and acetylcysteine
| Article | Year |
|---|---|
The anecdotal antidotes.
Topics: Acetylcysteine; Adult; Aged; Animals; Antidotes; Child; Cimetidine; Female; Ferrocyanides; Folic Acid; Heart Diseases; Humans; Magnesium; Male; Middle Aged; Naloxone; Niacinamide; Physostigmine; Poisoning; Pyridoxine; Thioctic Acid | 1984 |
Thiol homeostasis and supplements in physical exercise.
Topics: Acetylcysteine; Adolescent; Adult; Age Factors; Aged; Animals; Dietary Supplements; Dogs; Exercise; Female; Gene Expression Regulation, Enzymologic; Glutathione; Homeostasis; Humans; Male; Mice; Middle Aged; Muscle, Skeletal; Oxidative Stress; Rats; Riboflavin; Selenium; Signal Transduction; Sulfhydryl Compounds; Thioctic Acid | 2000 |
Nutrients and HIV: part three - N-acetylcysteine, alpha-lipoic acid, L-glutamine, and L-carnitine.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Carnitine; Complementary Therapies; Glutamine; HIV Infections; Humans; Thioctic Acid; Ubiquinone | 2000 |
Antioxidant effects of sulfur-containing amino acids.
Topics: Acetylcysteine; Amino Acids, Sulfur; Antioxidants; Cysteine; Glutathione; Methionine; Structure-Activity Relationship; Taurine; Thioctic Acid; Tiopronin | 2004 |
Arsenic and lead induced free radical generation and their reversibility following chelation.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E | 2007 |
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.
Topics: Acetylcysteine; Alzheimer Disease; Fibroblasts; Humans; Immunohistochemistry; Mitochondria; Oxidative Stress; Thioctic Acid | 2007 |
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc | 2007 |
Antioxidant therapy: current status and future prospects.
Topics: Acetylcysteine; Animals; Antioxidants; Antipyrine; Ascorbic Acid; Edaravone; Humans; Polyphenols; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin E | 2011 |
Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): a systematic review.
Topics: Acetylcarnitine; Acetylcysteine; Antineoplastic Agents; Dietary Supplements; Fatty Acids, Omega-3; Glutamine; Glutathione; Humans; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Thioctic Acid; Trace Elements; Vitamins | 2013 |
Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review.
Topics: Acetylcysteine; Antipsychotic Agents; Ascorbic Acid; Databases, Factual; Diet, Gluten-Free; Dietary Supplements; Fatty Acids, Unsaturated; Folic Acid; Glutamates; Humans; Melatonin; Oxidative Stress; Randomized Controlled Trials as Topic; Schizophrenia; Thioctic Acid; Vitamin B Complex; Vitamin D; Vitamin E | 2014 |
Pleiotropic Properties of Valsartan: Do They Result from the Antiglycooxidant Activity? Literature Review and
Topics: Acetylcysteine; Animals; Antioxidants; Captopril; Chloramines; Chromans; Fructose; Glucose; Glycosylation; Humans; Metformin; Oxidation-Reduction; Pyruvaldehyde; Serum Albumin, Bovine; Thioctic Acid; Tosyl Compounds; Valsartan | 2021 |
9 trial(s) available for thioctic acid and acetylcysteine
| Article | Year |
|---|---|
Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans.
Topics: Acetylcysteine; Adult; Antioxidants; Area Under Curve; Erythropoietin; Free Radical Scavengers; Humans; Hypoxia; Male; Malondialdehyde; Thioctic Acid | 2002 |
Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
Topics: Acetylcysteine; Antioxidants; Child; Child, Preschool; Female; Glutathione; Humans; Infant; Kwashiorkor; Male; Oxidative Stress; Pilot Projects; Sulfhydryl Compounds; Thioctic Acid | 2005 |
Complications & side effects. Supplements and CD4+ counts: study finds surprising results.
Topics: Acetylcarnitine; Acetylcysteine; Antioxidants; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; HIV Infections; Humans; Peripheral Nervous System Diseases; Placebos; Thioctic Acid; Viral Load; Vitamins | 2004 |
Effect of cysteine derivatives administration in healthy men exposed to intense resistance exercise by evaluation of pro-antioxidant ratio.
Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Catalase; Exercise; Glutathione Peroxidase; Health; Humans; Male; Oxidative Stress; Superoxide Dismutase; Taurine; Thiobarbituric Acid Reactive Substances; Thioctic Acid; Time Factors | 2007 |
The comparison of antioxidant and hematological properties of N-acetylcysteine and alpha-lipoic acid in physically active males.
Topics: Acetylcysteine; Administration, Oral; Adolescent; Antioxidants; Biomarkers; Cross-Over Studies; Double-Blind Method; Erythrocyte Indices; Erythrocytes; Erythropoietin; Exercise; Glutathione; Hematocrit; Hemoglobins; Humans; Lipid Peroxidation; Male; Protein Carbonylation; Thiobarbituric Acid Reactive Substances; Thioctic Acid; Time Factors; Young Adult | 2009 |
Effects of sulphur-containing compounds on plasma redox status in muscle-damaging exercise.
Topics: Acetylcysteine; Antioxidants; Dose-Response Relationship, Drug; Exercise; Humans; Male; Oxidation-Reduction; Protein Carbonylation; Resistance Training; Sulfhydryl Compounds; Taurine; Thiobarbituric Acid Reactive Substances; Thioctic Acid; Uric Acid; Young Adult | 2009 |
Antioxidants Taken Orally prior to Diagnostic Radiation Exposure Can Prevent DNA Injury.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; beta Carotene; Biomarkers; Bone Neoplasms; DNA Breaks, Double-Stranded; Drug Combinations; Histones; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasm Staging; Ontario; Oxidative Stress; Predictive Value of Tests; Prospective Studies; Radiation Injuries; Radiopharmaceuticals; Technetium Tc 99m Medronate; Thioctic Acid; Time Factors; Treatment Outcome | 2017 |
Effectiveness of an antioxidant preparation with N-acetyl cysteine, alpha lipoic acid and bromelain in the treatment of endometriosis-associated pelvic pain: LEAP study.
Topics: Acetylcysteine; Adult; Antioxidants; Bromelains; Drug Combinations; Endometriosis; Female; Humans; Pelvic Pain; Pregnancy; Thioctic Acid | 2018 |
Prospective randomized multicentre comparison on sibling oocytes comparing G-Series media system with antioxidants versus standard G-Series media system.
Topics: Acetylcarnitine; Acetylcysteine; Adult; Antioxidants; Culture Media; Embryo Culture Techniques; Embryo Transfer; Embryonic Development; Female; Fertilization in Vitro; Humans; Oocytes; Pregnancy; Pregnancy Rate; Prospective Studies; Thioctic Acid | 2020 |
88 other study(ies) available for thioctic acid and acetylcysteine
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Fluorescence energy-transfer studies on the pyruvate dehydrogenase complex isolated from Azotobacter vinelandii.
Topics: Acetylcysteine; Azotobacter; Binding Sites; Energy Transfer; Flavin-Adenine Dinucleotide; Fluorescence; Hydroxylamines; Maleimides; Organophosphorus Compounds; Pyrimidines; Pyruvate Dehydrogenase Complex; Thiamine; Thioctic Acid | 1978 |
Toxicity of chemically generated nitric oxide towards pancreatic islet cells can be prevented by nicotinamide.
Topics: Acetylcysteine; Animals; Benzamides; Cell Survival; Cells, Cultured; Free Radical Scavengers; In Vitro Techniques; Islets of Langerhans; Kinetics; Niacinamide; Nitric Oxide; Nitroprusside; Penicillamine; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Sodium Cyanide; Thioctic Acid; Thiosulfate Sulfurtransferase; Vasodilator Agents | 1992 |
Alpha-lipoic acid is a potent inhibitor of NF-kappa B activation in human T cells.
Topics: Acetylcysteine; Antioxidants; Base Sequence; Binding Sites; DNA, Viral; HIV-1; Humans; Models, Biological; Molecular Sequence Data; NF-kappa B; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioctic Acid; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Scavenging of hypochlorous acid by lipoic acid.
Topics: Acetylcysteine; alpha 1-Antitrypsin; Enzyme Activation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypochlorous Acid; Kinetics; Oxidation-Reduction; Pancreatic Elastase; Thioctic Acid | 1991 |
The reactivity of thiol compounds with different redox states of leghaemoglobin: evidence for competing reduction and addition pathways.
Topics: 3-Mercaptopropionic Acid; Acetylcysteine; Cysteamine; Cysteine; Disulfides; Electron Spin Resonance Spectroscopy; Ferric Compounds; Glycine max; Hydrogen Peroxide; Leghemoglobin; Mercaptoethanol; Oxidation-Reduction; Sulfhydryl Compounds; Sulfides; Thioctic Acid | 1995 |
Thiamine disulfide as a potent inhibitor of human immunodeficiency virus (type-1) production.
Topics: Acetylcysteine; Antiviral Agents; Cell Division; Cell Line; Cytopathogenic Effect, Viral; Gene Products, tat; HIV-1; Humans; tat Gene Products, Human Immunodeficiency Virus; Thiamine; Thioctic Acid; Virus Replication | 1994 |
Quenching of reactive oxidative species by probucol and comparison with other antioxidants.
Topics: Acetylcysteine; Antimutagenic Agents; Antioxidants; Ascorbic Acid; Benzophenones; Benzoquinones; Free Radicals; Oxidation-Reduction; Photolysis; Probucol; Reactive Oxygen Species; Spectrophotometry; Spectrum Analysis, Raman; Thioctic Acid; Vitamin E | 1996 |
Alpha-lipoic acid blocks HIV-1 LTR-dependent expression of hygromycin resistance in THP-1 stable transformants.
Topics: Acetylcysteine; Antioxidants; Cell Line; Drug Resistance; Gene Expression Regulation, Viral; HIV Core Protein p24; HIV Long Terminal Repeat; HIV-1; Humans; Hygromycin B; Macrophages; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Promoter Regions, Genetic; Tetrazolium Salts; Thiazoles; Thioctic Acid; Transfection; Tumor Necrosis Factor-alpha | 1996 |
Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis.
Topics: Acetylcysteine; Caprylates; Cell Size; DNA; Flow Cytometry; Fluorescence; Fluorescent Dyes; Glutamic Acid; Glutamine; Glutathione; Humans; Jurkat Cells; Kinetics; Lymphocytes; Male; Sulfhydryl Compounds; T-Lymphocytes; Thioctic Acid | 1997 |
Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Buthionine Sulfoximine; Cell Survival; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Glutathione; Kinetics; Rats; Thioctic Acid; Tumor Cells, Cultured | 1997 |
Antioxidants modulate acute solar ultraviolet radiation-induced NF-kappa-B activation in a human keratinocyte cell line.
Topics: Acetylcysteine; Antioxidants; Cell Line; Free Radicals; Gene Expression; Humans; Keratinocytes; NF-kappa B; Radiation-Protective Agents; Silymarin; Skin; Skin Diseases; Thioctic Acid; Transcription Factor AP-1; Ultraviolet Rays | 1999 |
Acute cholestasis-induced renal failure: effects of antioxidants and ligands for the thromboxane A2 receptor.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Carbazoles; Cholestasis; Dinoprost; Glutathione; Ligands; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Sodium; Sulfonamides; Thioctic Acid; Thromboxane B2 | 1999 |
Superoxide anion-induced formation of inositol phosphates involves tyrosine kinase activation in smooth muscle cells from rat mesenteric artery.
Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genistein; Inositol Phosphates; Isoenzymes; Mesenteric Arteries; Muscle, Smooth, Vascular; Phospholipase C gamma; Protein Biosynthesis; Protein-Tyrosine Kinases; Rats; Signal Transduction; Superoxides; Thioctic Acid; Type C Phospholipases; Tyrphostins | 1999 |
Inhibition of store-operated calcium entry in human lymphocytes by radiation: protection by glutathione.
Topics: Acetylcysteine; Antioxidants; Biological Transport; Calcium; Cells, Cultured; Cesium Radioisotopes; Gamma Rays; Glutathione; Humans; Hydrogen Peroxide; Jurkat Cells; Lymphocytes; Manganese; Membrane Potentials; Spectrometry, Fluorescence; Superoxides; T-Lymphocytes; Thapsigargin; Thioctic Acid | 1999 |
Inhibition of the cytokine-mediated inducible nitric oxide synthase expression in rat insulinoma cells by phenyl N-tert-butylnitrone.
Topics: Acetylcysteine; Animals; Blotting, Northern; Cell Survival; Cyclic N-Oxides; Cytokines; Diabetes Mellitus, Type 1; Enzyme Induction; Enzyme Inhibitors; Free Radical Scavengers; Immunoblotting; Insulinoma; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrogen Oxides; Protective Agents; Rats; RNA, Messenger; Thioctic Acid; Tumor Cells, Cultured | 2000 |
Restoration of functional defects in peripheral blood mononuclear cells isolated from cancer patients by thiol antioxidants alpha-lipoic acid and N-acetyl cysteine.
Topics: Acetylcysteine; Adult; Aged; Antioxidants; Cell Cycle; Cytokines; fas Receptor; Flow Cytometry; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Middle Aged; Neoplasms; Nitric Oxide; Receptors, Interleukin-2; Thioctic Acid | 2000 |
Thiols can either enhance or suppress DNA damage induction by catecholestrogens.
Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; DNA Damage; Drug Resistance, Neoplasm; Estradiol; Estrogens, Catechol; Glutathione; Hydrogen Peroxide; Kinetics; Methotrexate; NAD; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thioctic Acid | 2001 |
NAC, glutamine, and alpha lipoic acid. Interview by John S. James.
Topics: Acetylcysteine; Complementary Therapies; Diet; Drug Therapy, Combination; Glutamine; HIV Infections; Humans; Thioctic Acid | 1997 |
The 8 most important supplements for people on HAART.
Topics: Acetylcysteine; Anti-HIV Agents; Antioxidants; Dietary Supplements; Drug Therapy, Combination; Glutamine; HIV Infections; Humans; Plants, Medicinal; Silybum marianum; Thioctic Acid; Vitamin B 12; Vitamins | 1999 |
alpha-Lipoic acid prevents the development of glucose-induced insulin resistance in 3T3-L1 adipocytes and accelerates the decline in immunoreactive insulin during cell incubation.
Topics: 3T3 Cells; Acetylcysteine; Adipocytes; Animals; Antioxidants; Biological Transport; Culture Media, Conditioned; Dose-Response Relationship, Drug; Drug Synergism; Glucose; Insulin; Insulin Resistance; Mice; Oxidative Stress; Thioctic Acid | 2001 |
Two ways to stimulate glutathione.
Topics: Acetylcysteine; Antioxidants; Glutathione; HIV Infections; Humans; Thioctic Acid | 2001 |
Lipoic acid increases glutathione production and enhances the effect of mercury in human cell lines.
Topics: Acetylcysteine; Antioxidants; Dithiothreitol; Drug Synergism; Glutathione; HeLa Cells; Hepatocytes; Homocysteine; Humans; Mercury; Thioctic Acid | 2002 |
Photoprotection by antioxidants against UVB-radiation-induced damage in pig skin organ culture.
Topics: Acetylcysteine; Administration, Topical; alpha-Tocopherol; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Biological Availability; Culture Techniques; Epidermis; Glutathione; Lipid Peroxidation; Skin; Skin Diseases; Swine; Thioctic Acid; Treatment Outcome; Ultraviolet Rays | 2003 |
Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y.
Topics: Acetylcysteine; Alzheimer Disease; Brain; Cells, Cultured; Estradiol; Free Radicals; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Neurons; Oxidative Stress; Signal Transduction; Thioctic Acid | 2003 |
The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice.
Topics: Acetylcysteine; Age Factors; Amyloid beta-Peptides; Animals; Antioxidants; Appetitive Behavior; Behavior, Animal; Blood-Brain Barrier; Brain; Cognition; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred Strains; Mice, Neurologic Mutants; Oxidative Stress; Specific Pathogen-Free Organisms; Thioctic Acid; Treatment Outcome | 2003 |
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates | 2003 |
Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-kappaB in transiently cotransfected heart cells.
Topics: Acetylcysteine; Animals; Cells, Cultured; Cocaine; Dose-Response Relationship, Drug; Free Radicals; Genes, Reporter; Glutathione; Morphine; Myocytes, Cardiac; Narcotics; NF-kappa B; Rats; Reactive Oxygen Species; Signal Transduction; Thioctic Acid; Transfection | 2003 |
Dihydrolipoic acid inhibits 15-lipoxygenase-dependent lipid peroxidation.
Topics: Acetylcysteine; Animals; Antioxidants; Arachidonate 15-Lipoxygenase; Dithionite; Free Radical Scavengers; Free Radicals; Glycine max; Humans; Linoleic Acid; Lipid Peroxidation; Lipoxygenase Inhibitors; Masoprocol; Rabbits; Reticulocytes; Thioctic Acid | 2003 |
Effect of single and combined supply of glutamine, glycine, N-acetylcysteine, and R,S-alpha-lipoic acid on glutathione content of myelomonocytic cells.
Topics: Acetylcysteine; Analysis of Variance; Antioxidants; Chromatography, High Pressure Liquid; Flow Cytometry; Free Radical Scavengers; Glutamine; Glutathione; Glycine; Humans; In Vitro Techniques; Models, Biological; Monocytes; Oxidative Stress; Thioctic Acid; U937 Cells | 2003 |
A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode.
Topics: Acetylcysteine; Biotin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Cystine; Electrochemistry; Electrodes; Glutathione; Gold; Homocysteine; Methionine; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Sulfur Compounds; Thioctic Acid | 2005 |
N-acetylcysteine decreases angiotensin II receptor binding in vascular smooth muscle cells.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Membrane; Disulfides; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Immunoblotting; Inositol Phosphates; Kinetics; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxygen; Phosphates; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Signal Transduction; Temperature; Thioctic Acid; Time Factors; Vitamin E | 2005 |
Glutathione turnover in human cell lines in the presence of agents with glutathione influencing potential with and without acivicin inhibition of gamma-glutamyltranspeptidase.
Topics: Acetylcysteine; Cell Line, Tumor; Copper; Ethylmaleimide; gamma-Glutamyltransferase; Glutathione; Humans; Hydrogen Peroxide; Hydroquinones; Isoxazoles; Mercury; Thioctic Acid | 2005 |
alpha-Lipoic acid and N-acetyl cysteine prevent zinc deficiency-induced activation of NF-kappaB and AP-1 transcription factors in human neuroblastoma IMR-32 cells.
Topics: Acetylcysteine; Cell Line, Tumor; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Neuroblastoma; NF-kappa B; Oxidants; Oxidative Stress; Phosphorylation; Thioctic Acid; Transcription Factor AP-1; Zinc | 2006 |
An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever.
Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Body Temperature; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fever; Hydroxybenzoates; Hydroxyl Radical; Isoquinolines; Lipopolysaccharides; Male; Rabbits; Receptors, N-Methyl-D-Aspartate; Thioctic Acid | 2006 |
Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cells, Cultured; Coenzymes; Epithelial Cells; Fluoresceins; Humans; Oxidative Stress; Radiation Protection; Selenomethionine; Thioctic Acid; Tocopherols; Ubiquinone; Vitamin E | 2006 |
The effect of different antioxidants on glutathione turnover in human cell lines and their interaction with hydrogen peroxide.
Topics: Acetylcysteine; Antioxidants; Drug Interactions; Glutathione; HeLa Cells; Humans; Hydrogen Peroxide; Isoxazoles; Phenanthrolines; Quercetin; Thioctic Acid | 2006 |
Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor.
Topics: Acetylcysteine; Angiotensin II; Animals; Animals, Newborn; Antioxidants; Catalase; Cell Enlargement; Cells, Cultured; Cyclic N-Oxides; Enzyme Activation; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NFATC Transcription Factors; Oxidants; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Signal Transduction; Thioctic Acid; Transcription Factor AP-1 | 2007 |
Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Fragmentation; Enzyme Activation; Humans; Liver Neoplasms; MAP Kinase Kinase 4; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Thioctic Acid; Tumor Suppressor Protein p53 | 2007 |
Effects of glutathione and N-acetyl cysteine on the antimycobacterial efficacy of isoniazid on Mycobacterium fortuitum in vitro.
Topics: Acetylcysteine; Antioxidants; Drug Interactions; Glutathione; Isoniazid; Microbial Sensitivity Tests; Mycobacterium fortuitum; Sulfhydryl Compounds; Thioctic Acid | 2006 |
Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcysteine; Alkynes; Animals; Antioxidants; Antiparkinson Agents; Biotransformation; Carrier Proteins; Cell Nucleus; Co-Repressor Proteins; Cystathionine gamma-Lyase; Cytosol; Dopamine; Drug Evaluation, Preclinical; Electron Transport Complex I; Enzyme Activation; Glutathione; Glycine; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Mesencephalon; Mice; Mice, Inbred C57BL; Molecular Chaperones; MPTP Poisoning; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nuclear Proteins; Oncogene Proteins; Parkinsonian Disorders; Peroxiredoxins; Phosphorylation; Protein Deglycase DJ-1; Protein Processing, Post-Translational; Protein Transport; Substantia Nigra; Thioctic Acid | 2007 |
Fluorimetric determination of some sulfur containing compounds through complex formation with terbium (Tb+3) and uranium (U+3).
Topics: Acetylcysteine; Carbocysteine; Fluorescent Dyes; Hydrogen-Ion Concentration; Molecular Structure; Organometallic Compounds; Pharmaceutical Preparations; Reproducibility of Results; Spectrometry, Fluorescence; Sulfur Compounds; Terbium; Thioctic Acid; Uranium | 2007 |
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Male; Mice; Mushroom Poisoning; Penicillin G; Random Allocation; Silybin; Silymarin; Thioctic Acid | 2007 |
Thiol supplementation inhibits metalloproteinase activity independent of glutathione status.
Topics: Acetylcysteine; Animals; Antioxidants; CHO Cells; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Glutathione; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloproteases; Sulfhydryl Compounds; Thioctic Acid | 2007 |
Antioxidant effects of methionine, alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Erythrocytes; Glutathione Peroxidase; Hemoglobins; Homocystine; Lead; Male; Malondialdehyde; Methionine; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Vitamin A; Vitamin E | 2008 |
Dietary supplementation with N-acetylcysteine, alpha-tocopherol and alpha-lipoic acid prevents age related decline in Na(+),K (+)-ATPase activity and associated peroxidative damage in rat brain synaptosomes.
Topics: Acetylcysteine; Aging; alpha-Tocopherol; Animals; Antioxidants; Brain; Dietary Supplements; Female; Free Radical Scavengers; Lipid Peroxidation; Male; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Thioctic Acid | 2008 |
Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.
Topics: Acetylcysteine; Animals; Antioxidants; Constriction; Disease Models, Animal; Glutathione Peroxidase; Ileum; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sexual Development; Sulfhydryl Compounds; Superoxide Dismutase; Thioctic Acid; Thioglycolates; Thiophenes | 2009 |
[Changes in matrix metalloproteinases activities in normal and transformed mouse fibroblasts under effect of antioxidants].
Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Cell Line, Transformed; Cell Transformation, Viral; Enzyme Inhibitors; Fibroblasts; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Thioctic Acid | 2008 |
[Effect of alpha-lipoic acid on the sensitivity of transformed fibroblasts to lysis by natural killer cells. Comparison with NAC action].
Topics: Acetylcysteine; Animals; Antioxidants; BALB 3T3 Cells; Cell Line, Transformed; Cell Transformation, Viral; Cytotoxicity, Immunologic; Fibroblasts; Free Radical Scavengers; Killer Cells, Natural; Mice; Thioctic Acid | 2009 |
[Effect of alpha-lipoic acid on fibroblasts 3T3 and 3T3-SV40. Comparison with N-acetylcysteine action].
Topics: 3T3 Cells; Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Cell Cycle; Cell Line, Transformed; Cell Transformation, Viral; Fibroblasts; Free Radical Scavengers; Glutathione; Mice; Microtubules; Simian virus 40; Thioctic Acid | 2009 |
Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis.
Topics: Acetylcysteine; Alkaptonuria; Antioxidants; Ascorbic Acid; Cells, Cultured; Coumaric Acids; Homogentisic Acid; Humans; Ochronosis; Oxidative Stress; Phytic Acid; Protein Carbonylation; Taurine; Thioctic Acid | 2010 |
Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.
Topics: Acetylcysteine; Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Ascorbic Acid; Benzodioxoles; Brain; Catechin; Cerebral Cortex; Cognition; Curcumin; Dietary Supplements; Folic Acid; Hippocampus; Humans; Immunoblotting; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Piperidines; Polyunsaturated Alkamides; Thioctic Acid; Vitamin B Complex; Vitamins | 2010 |
Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.
Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Curcumin; Enzyme Inhibitors; Free Radical Scavengers; Glutathione Disulfide; Glutathione Peroxidase; Lipid Peroxidation; Muscle, Skeletal; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid | 2011 |
[Decrease in tumorigenic activity of murine hepatoma cells after treatment with antioxidants and melatonin].
Topics: Acetylcysteine; Animals; Antioxidants; Carcinoma, Hepatocellular; Cell Cycle; Flow Cytometry; Humans; Injections, Subcutaneous; Liver Neoplasms; Melatonin; Mice; Mice, Inbred C3H; Thioctic Acid; Transplantation, Isogeneic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Curcumin; gamma-Glutamyltransferase; Glutathione; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 13; Rats; Rats, Wistar; Thioctic Acid; Transforming Growth Factor alpha | 2012 |
Comparison of the protective effects of antioxidant compounds in the liver and kidney of Cd- and Cr-exposed common carp.
Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Chromium; Curcumin; Glutathione; Kidney; Lipid Peroxidation; Liver; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid; Water Pollutants, Chemical | 2014 |
Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease.
Topics: Acetylcysteine; Antioxidants; Benzoquinones; DNA Adducts; Dopamine; Humans; Hydrogen-Ion Concentration; Kinetics; Melatonin; Monophenol Monooxygenase; Parkinson Disease; Resveratrol; Stilbenes; Thioctic Acid | 2011 |
Suppression of high pacing-induced ANP secretion by antioxidants in isolated rat atria.
Topics: Acetophenones; Acetylcysteine; Animals; Antioxidants; Atrial Function; Atrial Natriuretic Factor; Blood Pressure; Cardiac Pacing, Artificial; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Electric Stimulation; Enzyme Activation; Extracellular Fluid; Heart Atria; Hemodynamics; Hydrogen Peroxide; In Vitro Techniques; Male; Myocardial Contraction; NADPH Oxidase 4; NADPH Oxidases; Pyrogallol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Thioctic Acid | 2011 |
Combined treatment with antioxidants and immunosuppressants on cytokine release by human peripheral blood mononuclear cells - chemically injured keratocyte reaction.
Topics: Acetylcysteine; Antioxidants; Burns, Chemical; Cells, Cultured; Coculture Techniques; Cornea; Corneal Injuries; Corneal Keratocytes; Dexamethasone; Drug Combinations; Humans; Immunosuppressive Agents; Interleukin-6; Intramolecular Oxidoreductases; Leukocytes, Mononuclear; Macrophage Migration-Inhibitory Factors; Matrix Metalloproteinase 9; Mycophenolic Acid; Sirolimus; Sodium Hydroxide; Thioctic Acid; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2011 |
A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Antioxidants; Apoptosis; Blotting, Western; Cisplatin; Colorectal Neoplasms; Doxorubicin; Doxycycline; Drug Resistance, Neoplasm; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Microscopy, Confocal; Models, Biological; NF-E2-Related Factor 2; Phosphatidylethanolamine Binding Protein; Protein Binding; Proteolysis; RNA Interference; Thioctic Acid | 2012 |
α-Lipoic acid increases tolerance of cardiomyoblasts to glucose/glucose oxidase-induced injury via ROS-dependent ERK1/2 activation.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Cytoprotection; Enzyme Activation; Glucose; Glucose Oxidase; Hydrogen Peroxide; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Thioctic Acid | 2012 |
Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine.
Topics: Acetylcysteine; Adult; Antioxidants; Cells, Cultured; Chromosomal Instability; Fanconi Anemia; Female; Humans; Lymphocytes; Male; Oxidative Stress; Thioctic Acid; Young Adult | 2012 |
Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain.
Topics: Acetylcysteine; alpha-Tocopherol; Animals; Brain; Cell Nucleus; Cytokines; Dietary Supplements; Enzyme-Linked Immunosorbent Assay; Inflammation; Mitochondria; NF-kappa B; Oxidative Stress; Rats; Reactive Oxygen Species; Thioctic Acid | 2012 |
Sodium butyrate potentiates carbon tetrachloride-induced acute liver injury in mice.
Topics: Acetylcysteine; Animals; Butyrates; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Liver; Male; Mice; Oxidative Stress; Thioctic Acid | 2012 |
Fragrance chemicals lyral and lilial decrease viability of HaCat cells' by increasing free radical production and lowering intracellular ATP level: protection by antioxidants.
Topics: Acetylcysteine; Adenosine Triphosphate; Aldehydes; Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Chromans; Cyclohexenes; Electron Transport Chain Complex Proteins; Glutathione; Humans; L-Lactate Dehydrogenase; Mice; Mitochondrial Membranes; NIH 3T3 Cells; Perfume; Reactive Oxygen Species; Thioctic Acid | 2013 |
Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy.
Topics: Acetylcysteine; Adenosine Triphosphate; Adrenoleukodystrophy; Age Factors; Analysis of Variance; Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Brain; Buthionine Sulfoximine; Cell Death; Chromatin; Cyclophilins; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Galactose; Gene Expression Regulation; Glucose; Glutathione; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Neuroprotective Agents; Oligopeptides; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Permeability; Reactive Oxygen Species; Thioctic Acid; Time Factors; Tubulin; Vitamin E | 2012 |
Protective effects of alpha lipoic acid versus N-acetylcysteine on ifosfamide-induced nephrotoxicity.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Glutathione; Ifosfamide; Kidney; Lipid Peroxidation; Male; Nitric Oxide; Oxidative Stress; Rats; Thioctic Acid | 2015 |
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria.
Topics: Acetylcysteine; Alkaptonuria; Antioxidants; Ascorbic Acid; Cell Line; Chondrocytes; Cytokines; Humans; Inflammation; Lipid Peroxidation; Phytic Acid; Serum Amyloid A Protein; Taurine; Thioctic Acid | 2013 |
Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats.
Topics: Acetylcysteine; Aging; alpha-Tocopherol; Animals; Antioxidants; Brain; Calcium; Dietary Supplements; Drug Evaluation, Preclinical; Drug Therapy, Combination; Learning Disabilities; Maze Learning; Membrane Potentials; Memory Disorders; Oxidative Stress; Potassium; Rats; Sodium; Synaptosomes; Thioctic Acid | 2014 |
Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; I-kappa B Kinase; I-kappa B Proteins; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mesangial Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Rats; Sepsis; Signal Transduction; Thioctic Acid; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2015 |
Alpha-lipoic acid and N-acetylcysteine protects intensive swimming exercise-mediated germ-cell depletion, pro-oxidant generation, and alteration of steroidogenesis in rat testis.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Body Weight; Corticosterone; Eating; Exercise Test; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Organ Size; Oxidative Stress; Phosphoproteins; Rats; Rats, Wistar; Spermatozoa; Stress, Physiological; Swimming; Testis; Testosterone; Thioctic Acid | 2014 |
α-Lipoic acid protected cardiomyoblasts from the injury induced by sodium nitroprusside through ROS-mediated Akt/Gsk-3β activation.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cytoprotection; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Myoblasts, Cardiac; Nitroprusside; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Thioctic Acid | 2014 |
[Comparative antioxidant action on the level of reactive oxygen species in normal and transformed fibroblasts].
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Transformed; Fluoresceins; Fluorescent Dyes; Hydrogen Peroxide; Mice; NIH 3T3 Cells; Reactive Oxygen Species; Thioctic Acid | 2013 |
Glutathione, N-acetylcysteine and lipoic acid down-regulate starvation-induced apoptosis, RANKL/OPG ratio and sclerostin in osteocytes: involvement of JNK and ERK1/2 signalling.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Apoptosis; Bone Diseases; Bone Remodeling; Cell Line; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Glycoproteins; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; Mice; Necrosis; Osteocytes; Osteoprotegerin; Oxidation-Reduction; Phosphorylation; RANK Ligand; Thioctic Acid | 2015 |
Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention.
Topics: Acetylcysteine; Adenine; Adolescent; Adult; Aged; Antioxidants; Blood Preservation; Buffers; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Female; Glucose; Glutathione; Humans; Hydrogen Peroxide; Inosine; Male; Middle Aged; Oxidation-Reduction; Peroxiredoxins; Phosphates; Pyruvic Acid; Solutions; Sulfhydryl Compounds; Thioctic Acid; Young Adult | 2015 |
Antioxidant supplementation during in vitro culture improves mitochondrial function and development of embryos from aged female mice.
Topics: Acetylcysteine; Age Factors; alpha-Tocopherol; Animals; Antioxidants; Embryo Culture Techniques; Embryonic Development; Female; Gene Expression; Mice; Mitochondria; Oxidative Stress; Sirtuins; Taurine; Thioctic Acid | 2015 |
The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Apoptosis; Bromelains; Cells, Cultured; Disease Models, Animal; Endometriosis; Endothelial Cells; Female; Humans; Inflammation; Mice; Mice, SCID; Microscopy, Fluorescence; Thioctic Acid; Tumor Necrosis Factor-alpha; Uterus; Vascular Cell Adhesion Molecule-1 | 2015 |
Lipoic acid and N-acetylcysteine prevent ammonia-induced inflammatory response in C6 astroglial cells: The putative role of ERK and HO1 signaling pathways.
Topics: Acetylcysteine; Ammonia; Animals; Anti-Inflammatory Agents; Antioxidants; Astrocytes; Cell Line; Cytokines; Extracellular Signal-Regulated MAP Kinases; Glutathione; Heme Oxygenase (Decyclizing); Nitrites; Rats; S100 Calcium Binding Protein beta Subunit; Signal Transduction; Thioctic Acid | 2015 |
Multiple mechanisms of age-dependent accumulation of amyloid beta protein in rat brain: Prevention by dietary supplementation with N-acetylcysteine, α-lipoic acid and α-tocopherol.
Topics: Acetylcysteine; Aging; alpha-Tocopherol; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Dietary Supplements; Drug Therapy, Combination; Maze Learning; Peptide Fragments; Rats; Rats, Wistar; Thioctic Acid | 2016 |
[CELLS FORM AND THEIR SENSITIVITY TO LYTIC ACTIVITY OF NATURAL KILLER CELLS UNDER THE ANTIOXIDANT ACTION].
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Antioxidants; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Cell Shape; Coculture Techniques; Cytotoxicity, Immunologic; Enzyme Repression; Killer Cells, Natural; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methionine Sulfoximine; Mice; NIH 3T3 Cells; Pyrrolidonecarboxylic Acid; Thiazolidines; Thioctic Acid | 2015 |
Antioxidants improve mouse preimplantation embryo development and viability.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Blastocyst; Body Size; Crown-Rump Length; Embryo Culture Techniques; Embryonic Development; Glutathione; Mice; Thioctic Acid; Time-Lapse Imaging | 2016 |
Poly-MVA attenuates 7,12- dimethylbenz[a]anthracene initiated and croton oil promoted skin papilloma formation on mice skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Animals; Carcinogens; Croton Oil; Dietary Supplements; Female; Free Radical Scavengers; Inflammation; Lipid Peroxidation; Mice; Molybdenum; N-Formylmethionine; Palladium; Papilloma; Rhodium; Ruthenium; Skin Neoplasms; Thioctic Acid; Vitamin B Complex | 2017 |
Antioxidants improve IVF outcome and subsequent embryo development in the mouse.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Blastocyst; Culture Media; Disease Models, Animal; Embryo Culture Techniques; Embryonic Development; Female; Fertilization in Vitro; Hydrogen Peroxide; In Vitro Oocyte Maturation Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Oocyte Retrieval; Oocytes; Oxidative Stress; Oxygen; Spermatozoa; Thioctic Acid; Treatment Outcome | 2017 |
N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms.
Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Dietary Supplements; Estrogens; Female; Glutathione; Inflammation; Lipids; NF-E2-Related Factor 2; Ovariectomy; Oxidative Stress; Rats, Wistar; Thioctic Acid | 2019 |
Antioxidant supplementation partially rescues accelerated ovarian follicle loss, but not oocyte quality, of glutathione-deficient mice†.
Topics: Acetylcysteine; Animals; Antioxidants; Diet; Dietary Supplements; Estrous Cycle; Female; Genotype; Glutamate-Cysteine Ligase; Glutathione; Male; Mice; Mice, Knockout; Oocytes; Ovarian Follicle; Thioctic Acid | 2020 |
Diverse Impact of N-Acetylcysteine or Alpha-Lipoic Acid Supplementation during High-Fat Diet Regime on Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Visceral and Subcutaneous Adipose Tissue.
Topics: Acetylcysteine; Animals; Antioxidants; Diet, High-Fat; Dietary Supplements; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Obesity; Rats; Rats, Wistar; Subcutaneous Fat; Thioctic Acid | 2022 |
Diverse impact of N-acetylcysteine or alpha-lipoic acid supplementation during high-fat diet regime on fatty acid transporters in visceral and subcutaneous adipose tissue.
Topics: Acetylcysteine; Adipose Tissue; Animals; Antioxidants; Carrier Proteins; Diet, High-Fat; Dietary Supplements; Fatty Acids; Male; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Subcutaneous Fat; Thioctic Acid | 2022 |
N-acetyl-l-cysteine and alpha lipoic acid are protective supplement on human sperm parameters in cryopreservation of asthenoteratozoospermia patients.
Topics: Acetylcysteine; Antioxidants; Asthenozoospermia; Cryopreservation; Humans; Male; NF-E2-Related Factor 2; Semen Preservation; Sperm Motility; Spermatozoa; Thioctic Acid | 2022 |