thioctic acid has been researched along with acetylcarnitine in 52 studies
*Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS. [MeSH]
*Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 24 (46.15) | 29.6817 |
| 2010's | 25 (48.08) | 24.3611 |
| 2020's | 3 (5.77) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, U; Khan, MJ; Quirk, WS; Seidman, MD; Shirwany, N | 1 |
| Ames, BN; Bartholomew, JC; Hagen, TM; Ingersoll, RT; Liu, J; Lykkesfeldt, J; Vinarsky, V; Wehr, CM | 1 |
| Ames, BN; Killilea, DW; Liu, J | 1 |
| Ames, BN; Cotman, CW; Gharib, AM; Hagen, TM; Head, E; Ingersoll, RT; Liu, J; Yuan, W | 1 |
| Ames, BN; Atamna, H; Kuratsune, H; Liu, J | 1 |
| Hagen, TM; Moreau, R; Suh, JH; Visioli, F | 1 |
| Beal, MF | 1 |
| Ames, BN | 1 |
| Bastianetto, S; Quirion, R | 1 |
| Abdul, HM; Butterfield, DA | 1 |
| Gokce, N; Hagen, TM; Hamburg, NM; Holbrook, M; Huang, AL; Keaney, JF; McMackin, CJ; Vita, JA; Weller, S; Widlansky, ME | 1 |
| Rosendorff, C | 1 |
| Ames, BN; Araujo, JA; Hagen, TM; Milgram, NW; Treadwell, BV | 1 |
| Cotman, CW; Li, X; Liu, J; Liu, K; Packer, L; Ren, J; Shen, W; Tian, C; Yang, L | 1 |
| Head, E; Li, X; Liu, J; Liu, K; Packer, L; Ren, J; Sharman, E; Shen, W; Tian, C; Yang, L | 1 |
| Ames, BN; Atamna, W; Killilea, DW; Lal, A; Suh, JH | 1 |
| Aliev, G; Ames, BN; Chen, SG; Fischbach, K; Gasimov, E; Liu, J; Obrenovich, ME; Pacheco, GJ; Perry, G; Richardson, AG; Shenk, JC; Smith, MA; Ward, WF | 1 |
| Chow, CS; Kennedy, SH; Konarski, JZ; McIntyre, RS; Soczynska, JK; Woldeyohannes, HO | 1 |
| Loiero, M; Memeo, A | 1 |
| Ames, BN; Cotman, CW; Gao, F; Liu, J; Long, J; Tong, L | 1 |
| Chan, A; Shea, TB; Suchy, J | 1 |
| Aliev, G; Alvarez, LM; Ames, BN; Fischbach, K; Gasimov, E; Lamanna, JC; Liu, J; Obrenovich, ME; Puchowicz, M; Shenk, JC; Xu, K | 1 |
| Araujo, JA; Christie, LA; Cotman, CW; de Rivera, C; Head, E; Milgram, NW; Opii, WO | 1 |
| Kumar, A; Nagesh Babu, G; Singh, RL | 1 |
| Ao, N; Jia, H; Li, X; Liu, J; Luo, C; Shen, W; Wang, X; Yan, B; Zhang, H | 1 |
| Kuritzky, L | 1 |
| Antinori, S; Caramma, I; Cesari, M; Cossarizza, A; Galli, M; Menzaghi, B; Milazzo, L; Nasi, M; Sangaletti, O; Zanone Poma, B | 1 |
| Abo-Elmatty, DM; El-Awady, el-SE; Moustafa, YM; Radwan, A | 1 |
| Carvalho, F; Ponte, F; Porto, B | 1 |
| Abo-Elmatty, DM; Shaalan, AA; Zaitone, SA | 1 |
| Airey, C; Colosimo, M; Linnane, AW; Masci, PP; Schloss, JM; Vitetta, L | 1 |
| Beaulieu, A; Brennan, BP; Cohen, BM; Coit, CE; Hudson, JI; Jensen, JE; Pope, HG; Renshaw, PF | 1 |
| French, SW; Kathirvel, E; Morgan, K; Morgan, TR | 1 |
| Phillipson, OT | 1 |
| Mehrotra, A; Sandhir, R | 1 |
| Feng, Z; Li, Y; Liu, J; Long, J; Peng, Y; Qu, L; Shi, W | 1 |
| Bao, YH; Gao, CQ; Ji, C; Jia, R; Ma, QG; Zhang, JY; Zhang, Y; Zhao, LH | 1 |
| Banerjee, SK; Kanwal, A; Mehrotra, A; Sandhir, R | 1 |
| Mehrotra, A; Sandhir, R; Sood, A | 1 |
| Cotman, CW; de Rivera, C; Milgram, NW; Snigdha, S | 1 |
| Erlandson, M; Legerski, P; Onysko, M; Potthoff, J | 1 |
| Gardner, DK; Soh, YM; Truong, TT | 1 |
| Huang, L; Liang, LF; Qi, ST; Sun, XF; Wang, WH; Xian, YX | 1 |
| Gardner, DK; Truong, T | 1 |
| Cross, AH; Evans, E; Piccio, L | 1 |
| Bizzarri, M; Cucina, A; Dinicola, S; Fuso, A; Monastra, G; Santiago-Reyes, M; Unfer, V; Verna, R | 1 |
| Rowin, J | 1 |
| Gamidov, SI; Ovchinnikov, RI; Popova, AY | 1 |
| Gardner, DK; Kuramoto, T; Mitzumoto, S; Montag, M; Tanaka, M; Yoshida, A | 1 |
| Augustyniak, J; Bhattacharya, M; Cheung, M; Dutta, A; Karanth, SS; Liput, M; Stachowiak, EK; Stachowiak, MK | 1 |
| D'Orio, M; De Vitis, R; Ferrari, F; Passiatore, M; Perna, A; Rocchi, L; Taccardo, G | 1 |
12 review(s) available for thioctic acid and acetylcarnitine
| Article | Year |
|---|---|
Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.
Topics: Acetylcarnitine; Animals; Antioxidants; Brain; Cell Line; Cellular Senescence; Cognition; Glutamic Acid; Humans; Hydroxylamines; Mitochondria; Neurons; Neuroprotective Agents; Oxidants; Thapsigargin; Thioctic Acid | 2002 |
Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.
Topics: Acetylcarnitine; Aging; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Dietary Supplements; Heart; Mitochondria; Myocardium; Oxidative Stress; Oxygen; Rats; Thioctic Acid | 2002 |
Bioenergetic approaches for neuroprotection in Parkinson's disease.
Topics: Acetylcarnitine; Coenzymes; Creatine; Energy Metabolism; Free Radicals; Ginkgo biloba; Humans; Mitochondria; Neuroprotective Agents; Niacinamide; Nootropic Agents; Parkinson Disease; Phytotherapy; Thioctic Acid; Ubiquinone | 2003 |
Delaying the mitochondrial decay of aging.
Topics: Acetylcarnitine; Aging; Animals; Biotin; Brain; Copper; Heme; Humans; Kinetics; Mitochondria; Pantothenic Acid; Protein Binding; Thioctic Acid; Vitamin B 6; Vitamin B Complex; Zinc | 2004 |
Natural antioxidants and neurodegenerative diseases.
Topics: Acetylcarnitine; Aging; Animals; Antioxidants; Brain; Food; Ginkgo biloba; Humans; Neurodegenerative Diseases; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Thioctic Acid | 2004 |
Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders?
Topics: Acetylcarnitine; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carnitine; Clinical Trials as Topic; Cognition Disorders; Drug Evaluation, Preclinical; Energy Metabolism; Female; Humans; Immunologic Factors; Male; Mice; Middle Aged; Mitochondria; Mood Disorders; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Psychotropic Drugs; Rats; Rats, Wistar; Thioctic Acid | 2008 |
Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): a systematic review.
Topics: Acetylcarnitine; Acetylcysteine; Antineoplastic Agents; Dietary Supplements; Fatty Acids, Omega-3; Glutamine; Glutathione; Humans; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Thioctic Acid; Trace Elements; Vitamins | 2013 |
Management of the aging risk factor for Parkinson's disease.
Topics: Acetylcarnitine; Adenosine Triphosphate; Aging; alpha-Synuclein; Antioxidant Response Elements; Carbohydrate Metabolism; Electron Transport; Energy Metabolism; Fatty Acids; Glial Cell Line-Derived Neurotrophic Factor; Humans; Inflammation; Melatonin; Mitochondria; Nitric Oxide; Oxidative Stress; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Proteostasis Deficiencies; Risk Factors; Thioctic Acid; Transcription Factors; Ubiquinone | 2014 |
Targeting neuropathic pain: consider these alternatives.
Topics: Acetylcarnitine; Capsaicin; Complementary Therapies; Family Practice; gamma-Linolenic Acid; Humans; Magnesium; Neuralgia; Peripheral Nervous System Diseases; Thioctic Acid; Vitamin B Complex | 2015 |
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Unsaturated; Folic Acid; Ginkgo biloba; Humans; Multiple Sclerosis; Niacin; Pantothenic Acid; Plant Preparations; Probiotics; Pyridoxine; Resveratrol; Riboflavin; Tea; Thiamine; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamins | 2018 |
Natural products - alpha-lipoic acid and acetyl-L-carnitine - in the treatment of chemotherapy-induced peripheral neuropathy.
Topics: Acetylcarnitine; Animals; Antineoplastic Agents; Biological Products; Humans; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Thioctic Acid | 2018 |
Integrative neuromuscular medicine: Neuropathy and neuropathic pain: Consider the alternatives.
Topics: Acetylcarnitine; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Diet; Diet Therapy; Dietary Supplements; Dysbiosis; Exercise; Exercise Therapy; Fatty Acids, Omega-3; Folic Acid; Gastrointestinal Microbiome; Humans; Integrative Medicine; Life Style; Metabolic Syndrome; Neuralgia; Peripheral Nervous System Diseases; Pyridoxal Phosphate; Thioctic Acid; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency; Vitamin D | 2019 |
8 trial(s) available for thioctic acid and acetylcarnitine
| Article | Year |
|---|---|
Complications & side effects. Supplements and CD4+ counts: study finds surprising results.
Topics: Acetylcarnitine; Acetylcysteine; Antioxidants; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; HIV Infections; Humans; Peripheral Nervous System Diseases; Placebos; Thioctic Acid; Viral Load; Vitamins | 2004 |
Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease.
Topics: Acetylcarnitine; Aged; Analysis of Variance; Biomarkers; Blood Flow Velocity; Blood Pressure; Boston; Brachial Artery; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Research Design; Thioctic Acid; Treatment Outcome; Vasodilation; Vitamin B Complex | 2007 |
Thioctic acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study.
Topics: Acetylcarnitine; Adult; Aged; Aged, 80 and over; Analgesics; Antioxidants; Double-Blind Method; Electromyography; Female; Humans; Inpatients; Intervertebral Disc Displacement; Male; Middle Aged; Pain; Pain Measurement; Sciatica; Surveys and Questionnaires; Thioctic Acid | 2008 |
Effect of antioxidants on mitochondrial function in HIV-1-related lipoatrophy: a pilot study.
Topics: Absorptiometry, Photon; Acetylcarnitine; Adult; Antioxidants; Body Composition; Breath Tests; Carbohydrate Metabolism; Carbon Isotopes; CD4-Positive T-Lymphocytes; Female; Glucose; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lipid Metabolism; Male; Methionine; Middle Aged; Mitochondria; Pilot Projects; Thioctic Acid | 2010 |
A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression.
Topics: Acetylcarnitine; Adult; Antidepressive Agents; Bipolar Disorder; Brain; Chi-Square Distribution; Drug Therapy, Combination; Energy Metabolism; Female; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Phosphocreatine; Psychiatric Status Rating Scales; Thioctic Acid; Time Factors; Treatment Outcome | 2013 |
[Double-blind, randomized placebo-controlled study of efficiency and safety of complex acetyl-L-carnitine, L-carnitine fumarate and alpha-lipoic acid (Spermactin Forte) for treatment of male infertility].
Topics: Acetylcarnitine; Adult; Carnitine; Double-Blind Method; Female; Fumarates; Humans; Infertility, Male; Male; Oxidative Stress; Pregnancy; Prospective Studies; Sperm Count; Sperm Motility; Spermatozoa; Thioctic Acid | 2019 |
Prospective randomized multicentre comparison on sibling oocytes comparing G-Series media system with antioxidants versus standard G-Series media system.
Topics: Acetylcarnitine; Acetylcysteine; Adult; Antioxidants; Culture Media; Embryo Culture Techniques; Embryo Transfer; Embryonic Development; Female; Fertilization in Vitro; Humans; Oocytes; Pregnancy; Pregnancy Rate; Prospective Studies; Thioctic Acid | 2020 |
Clinical usefulness of nutraceutics with acetyl-L-carnitine, α-lipoic acid, phosphatidylserine, curcumin, C, E and B-group vitamins in patients awaiting for carpal tunnel release during COVID-19 pandemic: a randomized controlled open label prospective stu
Topics: Acetylcarnitine; Carpal Tunnel Syndrome; COVID-19; Curcumin; Humans; Pain; Pandemics; Phosphatidylserines; Prospective Studies; Thioctic Acid; Treatment Outcome; Vitamin B Complex | 2023 |
32 other study(ies) available for thioctic acid and acetylcarnitine
| Article | Year |
|---|---|
Biologic activity of mitochondrial metabolites on aging and age-related hearing loss.
Topics: Acetylcarnitine; Aging; Animals; Auditory Threshold; Biological Transport; Cell Membrane; Cochlear Nerve; DNA Primers; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Evoked Potentials, Auditory, Brain Stem; Free Radicals; Gene Deletion; Mitochondria; Polymerase Chain Reaction; Presbycusis; Random Allocation; Rats; Rats, Inbred F344; Reactive Oxygen Species; Thioctic Acid | 2000 |
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.
Topics: Acetylcarnitine; Age Factors; Animals; Antioxidants; Ascorbic Acid; Fluoresceins; Hepatocytes; Lipid Peroxidation; Male; Malondialdehyde; Nootropic Agents; Oxidative Stress; Oxygen; Protein Binding; Rats; Rats, Inbred F344; Thioctic Acid; Time Factors | 2002 |
Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.
Topics: Acetylcarnitine; Aging; Aldehydes; Animals; Antioxidants; Brain; Breast; Carnitine O-Acetyltransferase; Columbidae; Cross-Linking Reagents; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Nootropic Agents; Oxygen; Protein Binding; Rats; Rats, Inbred F344; Spectrophotometry; Substrate Specificity; Thioctic Acid | 2002 |
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.
Topics: Acetylcarnitine; Age Factors; Animal Feed; Animals; Antioxidants; Brain; DNA; Hippocampus; Immunohistochemistry; Male; Maze Learning; Memory; Microscopy, Electron; Mitochondria; Nootropic Agents; Oxidative Stress; Oxygen; Rats; Rats, Inbred F344; RNA; Thioctic Acid; Time Factors | 2002 |
Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.
Topics: Acetylcarnitine; Aldehydes; Alzheimer Disease; Animals; Apoptosis; Cell Survival; Cerebral Cortex; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Lipid Peroxidation; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Thioctic Acid; Tyrosine | 2007 |
More light please.
Topics: Acetylcarnitine; Blood Flow Velocity; Blood Pressure; Brachial Artery; Coronary Artery Disease; Drug Therapy, Combination; Endothelium, Vascular; Humans; Thioctic Acid; Vasodilation; Vitamin B Complex | 2007 |
Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests.
Topics: Acetylcarnitine; Animals; Dogs; Learning; Placebos; Thioctic Acid | 2007 |
R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Acetylcarnitine; Adipocytes; Animals; Carnitine O-Palmitoyltransferase; DNA, Mitochondrial; Dose-Response Relationship, Drug; Fatty Acids; Insulin Resistance; Mice; Mitochondria; Models, Biological; Oxygen; PPAR alpha; PPAR gamma; Thioctic Acid | 2008 |
Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid.
Topics: Acetylcarnitine; Animals; Cell Line, Tumor; Insulinoma; Islets of Langerhans; Mitochondrial Diseases; Oleic Acid; Protective Agents; Rats; Thioctic Acid | 2008 |
Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts.
Topics: Acetylcarnitine; Antioxidants; Cell Line; Fibroblasts; Humans; Iron; Oxidative Stress; Thioctic Acid | 2008 |
Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.
Topics: Acetylcarnitine; Aging; Animals; Dietary Supplements; Hippocampus; Male; Mitochondria; Neurons; Random Allocation; Rats; Rats, Inbred F344; Thioctic Acid | 2009 |
Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.
Topics: Acetylcarnitine; Aging; Animals; Brain; Catalase; Electron Transport Chain Complex Proteins; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Oxidative Stress; Protein Carbonylation; Rats; Rats, Inbred F344; Stereoisomerism; Superoxide Dismutase; Thioctic Acid | 2009 |
Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance.
Topics: Acetylcarnitine; Alzheimer Disease; Animals; Antioxidants; Apolipoproteins E; Cognition Disorders; Dietary Supplements; Docosahexaenoic Acids; Drug Therapy, Combination; Folic Acid Deficiency; Glycerylphosphorylcholine; Iron; Maze Learning; Mice; Mice, Knockout; Nootropic Agents; Oxidative Stress; Phosphatidylserines; Reactive Oxygen Species; Thioctic Acid; Vitamin E Deficiency | 2009 |
The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease.
Topics: Acetylcarnitine; Aging; Alzheimer Disease; Animals; Antioxidants; Apolipoprotein E4; Brain; Cerebrovascular Circulation; Cognition; Dietary Supplements; Disease Models, Animal; Humans; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Thioctic Acid | 2009 |
Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.
Topics: Acetylcarnitine; Aging; Amides; Animals; Antioxidants; Cognition; Dietary Supplements; Dogs; Female; Male; Oxidation-Reduction; Thioctic Acid | 2009 |
Chronic pretreatment with acetyl-L-carnitine and ±DL-α-lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function.
Topics: Acetylcarnitine; Animals; Brain; Drug Therapy, Combination; Glutamic Acid; Male; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thioctic Acid; Treatment Outcome | 2011 |
Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.
Topics: Acetylcarnitine; alpha-Synuclein; Antioxidants; Drug Synergism; Humans; Mitochondria; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Rotenone; Thioctic Acid; Ubiquitin; Uncoupling Agents | 2010 |
Managing diabetic peripheral neuropathic pain in primary care.
Topics: Acetylcarnitine; Analgesics; Antidepressive Agents; Diabetic Neuropathies; Drug Therapy, Combination; Glycated Hemoglobin; Humans; Neurologic Examination; Patient Education as Topic; Primary Health Care; Thioctic Acid; Vitamin B Complex | 2010 |
Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies.
Topics: Acetylcarnitine; Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cardiotoxins; Cell Nucleus; Cisplatin; DNA Fragmentation; DNA, Mitochondrial; Glutathione; Heart; Lipid Peroxidation; Male; Oxidative Stress; Rats; Silymarin; Superoxide Dismutase; Thioctic Acid | 2011 |
Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes.
Topics: Acetylcarnitine; Adenosine Triphosphate; Adult; Cell Survival; Drug Interactions; Epoxy Compounds; Female; Glutathione; Humans; Lymphocytes; Male; Thioctic Acid; Young Adult | 2011 |
Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Antioxidants; Dietary Supplements; Dopamine; Dopaminergic Neurons; Hypokinesia; Lipid Peroxides; Male; Mitochondria; Neuroprotective Agents; Parkinson Disease; Protein Carbonylation; Psychomotor Disorders; Random Allocation; Rats; Rotenone; Substantia Nigra; Survival Analysis; Thioctic Acid; Vitamin B Complex | 2012 |
Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease.
Topics: Acetylcarnitine; Adipose Tissue; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Body Weight; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Insulin Resistance; Liver; Male; Mice; Mice, Inbred BALB C; Mitochondria; Non-alcoholic Fatty Liver Disease; Organ Size; Oxidative Stress; Thioctic Acid | 2013 |
Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation.
Topics: Acetylcarnitine; Animals; Antioxidants; Behavior, Animal; Brain; Chromatography, Thin Layer; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Glutathione; Huntington Disease; Lipid Peroxidation; Maze Learning; Motor Activity; Nitro Compounds; Propionates; Psychomotor Performance; Rats; Rats, Wistar; Rotarod Performance Test; Thioctic Acid | 2014 |
Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients.
Topics: Acetylcarnitine; Animals; Mitochondria; Mitochondrial Turnover; Muscular Atrophy; Muscular Disorders, Atrophic; Oxidative Stress; Phenylethyl Alcohol; Rats; Signal Transduction; Thioctic Acid; Ubiquinone | 2014 |
Effects of dietary α-lipoic acid, acetyl-l-carnitine, and sex on antioxidative ability, energy, and lipid metabolism in broilers.
Topics: Acetylcarnitine; Animal Feed; Animals; Antioxidants; Chickens; Diet; Dietary Supplements; Energy Metabolism; Female; Lipid Metabolism; Male; Random Allocation; Sex Factors; Thioctic Acid | 2014 |
Mitochondrial modulators in experimental Huntington's disease: reversal of mitochondrial dysfunctions and cognitive deficits.
Topics: Acetylcarnitine; Animals; Cognition Disorders; Drug Therapy, Combination; Female; Huntington Disease; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Mitochondrial Swelling; Nitro Compounds; Oxidative Stress; Propionates; Rats, Wistar; Thioctic Acid | 2015 |
Mitochondrial modulators improve lipid composition and attenuate memory deficits in experimental model of Huntington's disease.
Topics: Acetylcarnitine; Animals; Behavior, Animal; Brain; Cholesterol; Chromatography, Thin Layer; Cognition; Disease Models, Animal; Drug Therapy, Combination; Female; Huntington Disease; Lipid Metabolism; Membrane Fluidity; Memory; Mitochondria; Mitochondrial Membranes; Motor Activity; Nitro Compounds; Nootropic Agents; Phospholipids; Propionates; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Thioctic Acid | 2015 |
Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine.
Topics: Acetylcarnitine; Aging; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Coenzymes; Cognition; Cognition Disorders; Dietary Supplements; Disease Models, Animal; Dogs; Female; Male; Memory, Long-Term; Thioctic Acid | 2016 |
Antioxidants improve mouse preimplantation embryo development and viability.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Blastocyst; Body Size; Crown-Rump Length; Embryo Culture Techniques; Embryonic Development; Glutathione; Mice; Thioctic Acid; Time-Lapse Imaging | 2016 |
Protective effect of antioxidants on the pre-maturation aging of mouse oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcarnitine; Animals; Antioxidants; Cell Differentiation; Cell Nucleus; Cellular Senescence; Female; Mice; Mice, Inbred ICR; Mitochondria; Oocytes; Oxidative Stress; Primary Cell Culture; Sodium Citrate; Spindle Apparatus; Thioctic Acid | 2017 |
Antioxidants improve IVF outcome and subsequent embryo development in the mouse.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Blastocyst; Culture Media; Disease Models, Animal; Embryo Culture Techniques; Embryonic Development; Female; Fertilization in Vitro; Hydrogen Peroxide; In Vitro Oocyte Maturation Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Oocyte Retrieval; Oocytes; Oxidative Stress; Oxygen; Spermatozoa; Thioctic Acid; Treatment Outcome | 2017 |
A proof of concept 'phase zero' study of neurodevelopment using brain organoid models with Vis/near-infrared spectroscopy and electrophysiology.
Topics: Acetylcarnitine; Brain; Case-Control Studies; Cell Line; Choline; Electron Transport Complex IV; Electrophysiology; Female; Humans; Induced Pluripotent Stem Cells; Male; Mitochondria; Organoids; Proof of Concept Study; Schizophrenia; Spectroscopy, Near-Infrared; Thioctic Acid; Ubiquinone | 2020 |