Page last updated: 2024-08-22

thiocholchicine and podophyllotoxin

thiocholchicine has been researched along with podophyllotoxin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D1
Bastow, KF; Brossi, A; Guan, J; Hamel, E; Lee, KH; Tachibana, Y; Zhu, XK1
Cushman, M; Hamel, E; Lee, DJ; Mu, F; Pryor, DE1
Borlak, J; Cappelletti, G; Cartelli, D; Danieli, B; Fontana, G; Giardini, A; Passarella, D; Peretto, B; Ronchi, C; Sacchetti, A; Silvani, A1
Blasco y Yepes, R; Borlak, J; Cappelletti, G; Cartelli, D; Danieli, B; Fontana, G; Passarella, D; Peretto, B; Ronchi, C; Snaith, J1
Lee, KH1
Danieli, B; Giardini, A; Lesma, G; Passarella, D; Peretto, B; Pratesi, G; Sacchetti, A; Silvani, A; Zunino, F1

Reviews

1 review(s) available for thiocholchicine and podophyllotoxin

ArticleYear
Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
    Journal of natural products, 2010, Mar-26, Volume: 73, Issue:3

    Topics: Anti-HIV Agents; Biological Factors; Drug Design; Molecular Structure; Pharmaceutical Preparations; Plants, Medicinal

2010

Other Studies

6 other study(ies) available for thiocholchicine and podophyllotoxin

ArticleYear
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

1991
Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Division; Colchicine; DNA; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; KB Cells; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

1998
Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A.
    Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9

    Topics: Antineoplastic Agents; Biopolymers; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Phenols; Salicylamides; Stilbenes; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured

2003
Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Alkaloids; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colchicine; Combinatorial Chemistry Techniques; Dimerization; Drug Design; Humans; Podophyllotoxin; Radiation-Sensitizing Agents; Swine; Taxoids; Tubulin; Tubulin Modulators; Vinblastine; Vinorelbine

2008
Synthesis and biological evaluation of novel thiocolchicine-podophyllotoxin conjugates.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Animals; Cattle; Cell Line, Tumor; Colchicine; Fluorescent Antibody Technique; Glutathione; Humans; Inhibitory Concentration 50; Mice; Podophyllotoxin; Protein Multimerization; Protein Structure, Quaternary; Tubulin

2010
Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction.
    The Journal of organic chemistry, 2006, Mar-31, Volume: 71, Issue:7

    Topics: Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Colchicine; Combinatorial Chemistry Techniques; Disulfides; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Molecular Conformation; Podophyllotoxin; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2006