Page last updated: 2024-08-22

thiocholchicine and 2-demethylthiocolchicine

thiocholchicine has been researched along with 2-demethylthiocolchicine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brossi, A; Chignell, CF; Dumont, R; Quinn, FR; Suffness, M1
Brossi, A; Chignell, CF; Kerekes, P; Quinn, FR; Sharma, PN1
Bastow, KF; Brossi, A; Guan, J; Hamel, E; Lee, KH; Tachibana, Y; Zhu, XK1
Brossi, A; Feng, J; Hamel, E; Kuo, SC; Lee, KH; Tropsha, A; Zhang, SX1

Other Studies

4 other study(ies) available for thiocholchicine and 2-demethylthiocolchicine

ArticleYear
A novel synthesis of colchicide and analogues from thiocolchicine and congeners: reevaluation of colchicide as a potential antitumor agent.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Antineoplastic Agents; Colchicine; Mice; Neoplasms, Experimental; Structure-Activity Relationship; Tubulin

1987
Synthesis and biological effects of novel thiocolchicines. 3. Evaluation of N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl) deacetylthiocolchicines, and O-ethyldemethylthiocolchicines. New synthesis of thiodemecolcine and antileukemic effects of 2-demet
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Colchicine; Demecolcine; Drug Evaluation; Lethal Dose 50; Leukemia P388; Leukemia, Experimental; Mice; Structure-Activity Relationship; Tubulin

1985
Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Division; Colchicine; DNA; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; KB Cells; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

1998
Antitumor agents. 199. Three-dimensional quantitative structure-activity relationship study of the colchicine binding site ligands using comparative molecular field analysis.
    Journal of medicinal chemistry, 2000, Jan-27, Volume: 43, Issue:2

    Topics: Antineoplastic Agents; Colchicine; Molecular Structure; Static Electricity; Structure-Activity Relationship

2000