Compounds > thioacetamide-s-oxide
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thioacetamide-s-oxide and thioacetamide

thioacetamide-s-oxide has been researched along with thioacetamide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Neal, RA; Vadi, HV1
Breau, AP; Field, L; Karkhanis, DW; Mitchell, WM1
Dyroff, MC; Neal, RA1
Fukuda, T; Kuroiwa, Y; Matsuura, Y; Takizawa, Y; Yoshida, T1
Chieli, E; Malvaldi, G1
Chung, MC; Leow, CK; Low, TY; Salto-Tellez, M1
Chilakapati, J; Hill, RA; Korrapati, MC; Latendresse, JR; Mehendale, HM; Warbritton, A1
Bohr, S; Iracheta-Velle, A; Iracheta-Vellve, A; Jindal, R; King, KR; Li, M; Milwid, JM; Parekkadan, B; Patel, SJ; Vitalo, A; Yarmush, ML1
Galeva, NA; Hajovsky, H; Hanzlik, RP; Koen, YM; Sarma, D; Staudinger, JL; Williams, TD2
Cui, W; Hajovsky, H; Hanzlik, RP; Hu, G; Koen, Y; Moore, DS; Sarma, D; Staudinger, JL1

Other Studies

11 other study(ies) available for thioacetamide-s-oxide and thioacetamide

ArticleYear
Microsomal activation of thioacetamide-S-oxide to a metabolite(s) that covalently binds to calf thymus DNA and other polynucleotides.
    Chemico-biological interactions, 1981, Volume: 35, Issue:1

    Topics: Acetamides; Animals; Biotransformation; Cattle; DNA; In Vitro Techniques; Male; Microsomes, Liver; NADP; Poly A; Poly G; Polynucleotides; Rats; RNA; Thioacetamide; Thymus Gland

1981
Thiono compounds. 3. Chemical oxidation of thioacetamide to a mutagenic S-oxide.
    Mutation research, 1984, Volume: 139, Issue:1

    Topics: Acetamides; Animals; Biotransformation; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Oxidation-Reduction; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity; Thioacetamide

1984
Studies of the mechanism of metabolism of thioacetamide s-oxide by rat liver microsomes.
    Molecular pharmacology, 1983, Volume: 23, Issue:1

    Topics: Acetamides; Animals; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Lysine; Male; Microsomes, Liver; Models, Chemical; Oxygenases; Rats; Serum Albumin, Bovine; Thioacetamide

1983
Induction of heme oxygenase and inhibition of delta-aminolevulinic acid synthetase of rat liver by thioacetamide and thioacetamide-S-oxide.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:5

    Topics: 5-Aminolevulinate Synthetase; Acetamides; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme Oxygenase (Decyclizing); Liver; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors

1983
Role of the microsomal FAD-containing monooxygenase in the liver toxicity of thioacetamide S-oxide.
    Toxicology, 1984, May-01, Volume: 31, Issue:1

    Topics: Acetamides; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Liver; Male; Microsomes, Liver; Necrosis; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Thioacetamide

1984
A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers.
    Proteomics, 2004, Volume: 4, Issue:12

    Topics: Animals; Down-Regulation; Fatty Acids; Ferritins; Fibrosis; Glutathione; Heme; Humans; Image Processing, Computer-Assisted; Iron; Lipid Peroxidation; Liver; Liver Cirrhosis; Methionine; Oxidative Stress; Oxygenases; Proteomics; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioacetamide; Time Factors; Trypsin; Up-Regulation

2004
Toxicokinetics and toxicity of thioacetamide sulfoxide: a metabolite of thioacetamide.
    Toxicology, 2007, Feb-12, Volume: 230, Issue:2-3

    Topics: Alanine Transaminase; Animals; Area Under Curve; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; DNA Replication; Dose-Response Relationship, Drug; Histocytochemistry; Liver; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Thioacetamide; Thymidine

2007
Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.
    Nature biotechnology, 2012, Jan-15, Volume: 30, Issue:2

    Topics: Acetaminophen; Animals; Boron Compounds; Chemical and Drug Induced Liver Injury; Connexins; Gap Junction beta-1 Protein; Gap Junctions; HeLa Cells; Humans; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Protective Agents; Thioacetamide

2012
Covalent modification of lipids and proteins in rat hepatocytes and in vitro by thioacetamide metabolites.
    Chemical research in toxicology, 2012, Sep-17, Volume: 25, Issue:9

    Topics: Animals; Cells, Cultured; Chromatography, Thin Layer; Hepatocytes; Male; Mass Spectrometry; Muramidase; Oxidation-Reduction; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; Thioacetamide

2012
Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes.
    Chemical research in toxicology, 2012, Sep-17, Volume: 25, Issue:9

    Topics: Animals; Cells, Cultured; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Hepatocytes; L-Lactate Dehydrogenase; Male; Rats; Rats, Sprague-Dawley; Thioacetamide

2012
Protein targets of thioacetamide metabolites in rat hepatocytes.
    Chemical research in toxicology, 2013, Apr-15, Volume: 26, Issue:4

    Topics: Animals; Cells, Cultured; Cytosol; Hepatocytes; Male; Microsomes, Liver; Mitochondria, Liver; Proteins; Proteomics; Rats; Rats, Sprague-Dawley; Thioacetamide

2013